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USPatent US8497368

Compile data set for download or QSAR
Found 81 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99280
PNG
(US8497368, 72)
Show SMILES CC(=NNC(N)=O)c1cnc2nnn(Cc3cc4cccnc4cc3F)c2n1 |w:2.2|
Show InChI InChI=1S/C17H14FN9O/c1-9(23-25-17(19)28)14-7-21-15-16(22-14)27(26-24-15)8-11-5-10-3-2-4-20-13(10)6-12(11)18/h2-7H,8H2,1H3,(H3,19,25,28)
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US Patent
n/an/a 0.200n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99273
PNG
(US8497368, 65)
Show SMILES NC(=O)NNC(=N)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1
Show InChI InChI=1S/C16H14N10O/c17-13(22-24-16(18)27)12-7-20-14-15(21-12)26(25-23-14)8-9-3-4-11-10(6-9)2-1-5-19-11/h1-7H,8H2,(H2,17,22)(H3,18,24,27)
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US Patent
n/an/a 0.200n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99254
PNG
(US8497368, 46)
Show SMILES C[C@H](c1nnc2ccc(nn12)C(C)=NNC(N)=O)c1ccc2ncccc2c1 |r,w:13.15|
Show InChI InChI=1S/C19H18N8O/c1-11(13-5-6-16-14(10-13)4-3-9-21-16)18-24-23-17-8-7-15(26-27(17)18)12(2)22-25-19(20)28/h3-11H,1-2H3,(H3,20,25,28)/t11-/m0/s1
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n/an/a 0.200n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99248
PNG
(US8497368, 40)
Show SMILES CC(=NNC(N)=O)c1ccc2nnc(Cc3c(F)cc4ncccc4c3F)n2n1 |w:2.2|
Show InChI InChI=1S/C18H14F2N8O/c1-9(23-26-18(21)29)13-4-5-15-24-25-16(28(15)27-13)7-11-12(19)8-14-10(17(11)20)3-2-6-22-14/h2-6,8H,7H2,1H3,(H3,21,26,29)
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n/an/a 0.300n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99274
PNG
(US8497368, 66)
Show SMILES NC(=O)NN=Cc1cnc2nnn(Cc3ccc4ncccc4c3)c2n1 |w:5.5|
Show InChI InChI=1S/C16H13N9O/c17-16(26)23-20-8-12-7-19-14-15(21-12)25(24-22-14)9-10-3-4-13-11(6-10)2-1-5-18-13/h1-8H,9H2,(H3,17,23,26)
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US Patent
n/an/a 0.300n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99281
PNG
(US8497368, 73)
Show SMILES CC(=O)NN=C(C)c1cnc2nnn(Cc3cc4cccnc4cc3F)c2n1 |w:4.3|
Show InChI InChI=1S/C18H15FN8O/c1-10(23-24-11(2)28)16-8-21-17-18(22-16)27(26-25-17)9-13-6-12-4-3-5-20-15(12)7-14(13)19/h3-8H,9H2,1-2H3,(H,24,28)
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n/an/a 0.400n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99228
PNG
(US8497368, 20)
Show SMILES CC(=NNC(N)=O)c1ccc2ncc(Cc3c(F)cc4ncccc4c3F)n2n1 |w:2.2|
Show InChI InChI=1S/C19H15F2N7O/c1-10(25-26-19(22)29)15-4-5-17-24-9-11(28(17)27-15)7-13-14(20)8-16-12(18(13)21)3-2-6-23-16/h2-6,8-9H,7H2,1H3,(H3,22,26,29)
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n/an/a 0.400n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99238
PNG
(US8497368, 30)
Show SMILES C[C@H](c1cnc2ccc(nn12)C(C)=NNC(N)=O)c1ccc2ncccc2c1 |r,w:13.15|
Show InChI InChI=1S/C20H19N7O/c1-12(14-5-6-17-15(10-14)4-3-9-22-17)18-11-23-19-8-7-16(26-27(18)19)13(2)24-25-20(21)28/h3-12H,1-2H3,(H3,21,25,28)/t12-/m0/s1
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n/an/a 0.400n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99283
PNG
(US8497368, 75)
Show SMILES CC(=NNC(=O)c1ccncc1)c1cnc2nnn(Cc3cc4cccnc4cc3F)c2n1 |w:2.2|
Show InChI InChI=1S/C22H16FN9O/c1-13(28-30-22(33)14-4-7-24-8-5-14)19-11-26-20-21(27-19)32(31-29-20)12-16-9-15-3-2-6-25-18(15)10-17(16)23/h2-11H,12H2,1H3,(H,30,33)
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n/an/a 0.5n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99257
PNG
(US8497368, 49)
Show SMILES CC(c1nnc2ccc(nn12)C(C)=NNC(N)=O)c1c(F)cc2ncccc2c1F |w:13.15|
Show InChI InChI=1S/C19H16F2N8O/c1-9(16-12(20)8-14-11(17(16)21)4-3-7-23-14)18-26-25-15-6-5-13(28-29(15)18)10(2)24-27-19(22)30/h3-9H,1-2H3,(H3,22,27,30)
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n/an/a 0.5n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99241
PNG
(US8497368, 33)
Show SMILES CC(=NNC(N)=O)c1ccc2nnc(n2n1)C(F)(F)c1ccc2ncccc2c1 |w:2.2|
Show InChI InChI=1S/C18H14F2N8O/c1-10(23-26-17(21)29)13-6-7-15-24-25-16(28(15)27-13)18(19,20)12-4-5-14-11(9-12)3-2-8-22-14/h2-9H,1H3,(H3,21,26,29)
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n/an/a 0.700n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99268
PNG
(US8497368, 60)
Show SMILES CN(N=C(C)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1)C(N)=O |w:2.1|
Show InChI InChI=1S/C18H17N9O/c1-11(24-26(2)18(19)28)15-9-21-16-17(22-15)27(25-23-16)10-12-5-6-14-13(8-12)4-3-7-20-14/h3-9H,10H2,1-2H3,(H2,19,28)
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n/an/a 0.800n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99284
PNG
(US8497368, 76)
Show SMILES CC(=Nn1cc(O)[nH]c1=O)c1cnc2nnn(Cc3cc4cccnc4cc3F)c2n1 |w:2.2|
Show InChI InChI=1S/C19H14FN9O2/c1-10(26-29-9-16(30)24-19(29)31)15-7-22-17-18(23-15)28(27-25-17)8-12-5-11-3-2-4-21-14(11)6-13(12)20/h2-7,9,30H,8H2,1H3,(H,24,31)/b26-10+
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n/an/a 0.900n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99211
PNG
(US8497368, 1 | US8497368, 17 | US8497368, 18)
Show SMILES CC(=NNC(N)=O)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1 |w:2.2|
Show InChI InChI=1S/C19H16FN7O/c1-11(24-25-19(21)28)16-4-5-18-23-10-14(27(18)26-16)8-13-7-12-3-2-6-22-17(12)9-15(13)20/h2-7,9-10H,8H2,1H3,(H3,21,25,28)
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n/an/a 1n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99245
PNG
(US8497368, 37)
Show SMILES CC(=NNC(N)=O)c1ccc2nnc(Cc3ccc4ncccc4c3)n2n1 |w:2.2|
Show InChI InChI=1S/C18H16N8O/c1-11(21-24-18(19)27)14-6-7-16-22-23-17(26(16)25-14)10-12-4-5-15-13(9-12)3-2-8-20-15/h2-9H,10H2,1H3,(H3,19,24,27)
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n/an/a 1n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99218
PNG
(US8497368, 8)
Show SMILES CN(N=C(C)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1)C(N)=O |w:2.1|
Show InChI InChI=1S/C20H18FN7O/c1-12(25-27(2)20(22)29)17-5-6-19-24-11-15(28(19)26-17)9-14-8-13-4-3-7-23-18(13)10-16(14)21/h3-8,10-11H,9H2,1-2H3,(H2,22,29)
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n/an/a 1n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99252
PNG
(US8497368, 44)
Show SMILES CC(=NN1CCOC1=O)c1ccc2nnc(Cc3c(F)cc4ncccc4c3F)n2n1 |w:2.2|
Show InChI InChI=1S/C20H15F2N7O2/c1-11(26-28-7-8-31-20(28)30)15-4-5-17-24-25-18(29(17)27-15)9-13-14(21)10-16-12(19(13)22)3-2-6-23-16/h2-6,10H,7-9H2,1H3
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n/an/a 1n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99221
PNG
(US8497368, 11)
Show SMILES C\C(=N/N1CC(=O)NC1=O)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1
Show InChI InChI=1S/C21H16FN7O2/c1-12(26-28-11-20(30)25-21(28)31)17-4-5-19-24-10-15(29(19)27-17)8-14-7-13-3-2-6-23-18(13)9-16(14)22/h2-7,9-11,30H,8H2,1H3,(H,25,31)/b26-12+
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n/an/a 1n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99211
PNG
(US8497368, 1 | US8497368, 17 | US8497368, 18)
Show SMILES CC(=NNC(N)=O)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1 |w:2.2|
Show InChI InChI=1S/C19H16FN7O/c1-11(24-25-19(21)28)16-4-5-18-23-10-14(27(18)26-16)8-13-7-12-3-2-6-22-17(12)9-15(13)20/h2-7,9-10H,8H2,1H3,(H3,21,25,28)
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n/an/a 1n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99286
PNG
(US8497368, 78)
Show SMILES CC(=NNC(=O)c1cccnc1)c1cnc2nnn(Cc3cc4cccnc4cc3F)c2n1 |w:2.2|
Show InChI InChI=1S/C22H16FN9O/c1-13(28-30-22(33)15-5-2-6-24-10-15)19-11-26-20-21(27-19)32(31-29-20)12-16-8-14-4-3-7-25-18(14)9-17(16)23/h2-11H,12H2,1H3,(H,30,33)
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n/an/a 1n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99282
PNG
(US8497368, 74)
Show SMILES COC(=O)NN=C(C)c1cnc2nnn(Cc3cc4cccnc4cc3F)c2n1 |w:5.4|
Show InChI InChI=1S/C18H15FN8O2/c1-10(23-25-18(28)29-2)15-8-21-16-17(22-15)27(26-24-16)9-12-6-11-4-3-5-20-14(11)7-13(12)19/h3-8H,9H2,1-2H3,(H,25,28)
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n/an/a 1n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99233
PNG
(US8497368, 25)
Show SMILES CC(=NNC(N)=O)c1ccc2ncc(C(O)c3c(F)cc4ncccc4c3F)n2n1 |w:2.2|
Show InChI InChI=1S/C19H15F2N7O2/c1-9(25-26-19(22)30)12-4-5-15-24-8-14(28(15)27-12)18(29)16-11(20)7-13-10(17(16)21)3-2-6-23-13/h2-8,18,29H,1H3,(H3,22,26,30)
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n/an/a 2n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99227
PNG
(US8497368, 19)
Show SMILES CC(=NNC(N)=O)c1ccc2ncc(Cc3ccc4ncccc4c3)n2n1 |w:2.2|
Show InChI InChI=1S/C19H17N7O/c1-12(23-24-19(20)27)16-6-7-18-22-11-15(26(18)25-16)10-13-4-5-17-14(9-13)3-2-8-21-17/h2-9,11H,10H2,1H3,(H3,20,24,27)
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n/an/a 2n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99240
PNG
(US8497368, 32)
Show SMILES CC(=NNC(N)=O)c1ccc2ncc(Cc3c(F)cc4n(C)ncc4c3F)n2n1 |w:2.2|
Show InChI InChI=1S/C18H16F2N8O/c1-9(24-25-18(21)29)14-3-4-16-22-7-10(28(16)26-14)5-11-13(19)6-15-12(17(11)20)8-23-27(15)2/h3-4,6-8H,5H2,1-2H3,(H3,21,25,29)
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n/an/a 3n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99213
PNG
(US8497368, 3)
Show SMILES CC(=O)NN=C(C)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1 |w:4.3|
Show InChI InChI=1S/C20H17FN6O/c1-12(24-25-13(2)28)18-5-6-20-23-11-16(27(20)26-18)9-15-8-14-4-3-7-22-19(14)10-17(15)21/h3-8,10-11H,9H2,1-2H3,(H,25,28)
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99229
PNG
(US8497368, 21)
Show SMILES CN(N=C(C)c1ccc2ncc(Cc3c(F)cc4ncccc4c3F)n2n1)C(N)=O |w:2.1|
Show InChI InChI=1S/C20H17F2N7O/c1-11(26-28(2)20(23)30)16-5-6-18-25-10-12(29(18)27-16)8-14-15(21)9-17-13(19(14)22)4-3-7-24-17/h3-7,9-10H,8H2,1-2H3,(H2,23,30)
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n/an/a 3n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99260
PNG
(US8497368, 52)
Show SMILES CC(=NNC(N)=O)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1 |w:2.2|
Show InChI InChI=1S/C17H15N9O/c1-10(22-24-17(18)27)14-8-20-15-16(21-14)26(25-23-15)9-11-4-5-13-12(7-11)3-2-6-19-13/h2-8H,9H2,1H3,(H3,18,24,27)
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99220
PNG
(US8497368, 10)
Show SMILES CC(=NN1CCOC1=O)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1 |w:2.2|
Show InChI InChI=1S/C21H17FN6O2/c1-13(25-27-7-8-30-21(27)29)18-4-5-20-24-12-16(28(20)26-18)10-15-9-14-3-2-6-23-19(14)11-17(15)22/h2-6,9,11-12H,7-8,10H2,1H3
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99275
PNG
(US8497368, 67)
Show SMILES CC(c1cc2cccnc2cc1F)n1nnc2ncc(nc12)C(C)=NNC(N)=O |w:24.28|
Show InChI InChI=1S/C18H16FN9O/c1-9(24-26-18(20)29)15-8-22-16-17(23-15)28(27-25-16)10(2)12-6-11-4-3-5-21-14(11)7-13(12)19/h3-8,10H,1-2H3,(H3,20,26,29)
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99250
PNG
(US8497368, 42)
Show SMILES CN(N=C(C)c1ccc2nnc(Cc3c(F)cc4ncccc4c3F)n2n1)C(N)=O |w:2.1|
Show InChI InChI=1S/C19H16F2N8O/c1-10(26-28(2)19(22)30)14-5-6-16-24-25-17(29(16)27-14)8-12-13(20)9-15-11(18(12)21)4-3-7-23-15/h3-7,9H,8H2,1-2H3,(H2,22,30)
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99246
PNG
(US8497368, 38)
Show SMILES CC(=Nn1cc(O)[nH]c1=O)c1ccc2nnc(Cc3ccc4ncccc4c3)n2n1 |w:2.2|
Show InChI InChI=1S/C20H16N8O2/c1-12(25-27-11-19(29)22-20(27)30)15-6-7-17-23-24-18(28(17)26-15)10-13-4-5-16-14(9-13)3-2-8-21-16/h2-9,11,29H,10H2,1H3,(H,22,30)/b25-12+
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99253
PNG
(US8497368, 45)
Show SMILES CC(=NNC(N)=O)c1ccc2nnc(Cc3cc4cccnc4cc3F)n2n1 |w:2.2|
Show InChI InChI=1S/C18H15FN8O/c1-10(22-25-18(20)28)14-4-5-16-23-24-17(27(16)26-14)8-12-7-11-3-2-6-21-15(11)9-13(12)19/h2-7,9H,8H2,1H3,(H3,20,25,28)
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99288
PNG
(US8497368, 80)
Show SMILES CCC(=NNC(N)=O)c1ccc2ncc(Cc3cc4cnn(C)c4cc3F)n2n1 |w:3.3|
Show InChI InChI=1S/C19H19FN8O/c1-3-15(24-25-19(21)29)16-4-5-18-22-10-13(28(18)26-16)7-11-6-12-9-23-27(2)17(12)8-14(11)20/h4-6,8-10H,3,7H2,1-2H3,(H3,21,25,29)
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99263
PNG
(US8497368, 55)
Show SMILES CC(=NN1CCOC1=O)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1 |w:2.2|
Show InChI InChI=1S/C19H16N8O2/c1-12(24-26-7-8-29-19(26)28)16-10-21-17-18(22-16)27(25-23-17)11-13-4-5-15-14(9-13)3-2-6-20-15/h2-6,9-10H,7-8,11H2,1H3
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM302354
PNG
(US8497368, 81)
Show SMILES C\C(=N/NC(N)=O)c1ccc2ncc(Cc3ccc4ncccc4c3)n2n1
Show InChI InChI=1S/C19H17N7O/c1-12(23-24-19(20)27)16-6-7-18-22-11-15(26(18)25-16)10-13-4-5-17-14(9-13)3-2-8-21-17/h2-9,11H,10H2,1H3,(H3,20,24,27)/b23-12+
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n/an/a 4n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99267
PNG
(US8497368, 59)
Show SMILES CC(N=N)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1
Show InChI InChI=1S/C16H14N8/c1-10(21-17)14-8-19-15-16(20-14)24(23-22-15)9-11-4-5-13-12(7-11)3-2-6-18-13/h2-8,10,17H,9H2,1H3
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99277
PNG
(US8497368, 69)
Show SMILES CC(=NNC(N)=O)c1ccc2ncc(Cc3cc4cnn(C)c4cc3F)n2n1 |w:2.2|
Show InChI InChI=1S/C18H17FN8O/c1-10(23-24-18(20)28)15-3-4-17-21-9-13(27(17)25-15)6-11-5-12-8-22-26(2)16(12)7-14(11)19/h3-5,7-9H,6H2,1-2H3,(H3,20,24,28)
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99237
PNG
(US8497368, 29)
Show SMILES CC(c1cnc2ccc(nn12)C(C)=NNC(N)=O)c1cc2cccnc2cc1F |w:13.15|
Show InChI InChI=1S/C20H18FN7O/c1-11(14-8-13-4-3-7-23-17(13)9-15(14)21)18-10-24-19-6-5-16(27-28(18)19)12(2)25-26-20(22)29/h3-11H,1-2H3,(H3,22,26,29)
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99226
PNG
(US8497368, 16)
Show SMILES CC(=NNC(N)=S)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1 |w:2.2|
Show InChI InChI=1S/C19H16FN7S/c1-11(24-25-19(21)28)16-4-5-18-23-10-14(27(18)26-16)8-13-7-12-3-2-6-22-17(12)9-15(13)20/h2-7,9-10H,8H2,1H3,(H3,21,25,28)
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99264
PNG
(US8497368, 56)
Show SMILES CC(=Nn1cc(O)[nH]c1=O)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1 |w:2.2|
Show InChI InChI=1S/C19H15N9O2/c1-11(25-28-10-16(29)23-19(28)30)15-8-21-17-18(22-15)27(26-24-17)9-12-4-5-14-13(7-12)3-2-6-20-14/h2-8,10,29H,9H2,1H3,(H,23,30)/b25-11+
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99239
PNG
(US8497368, 31)
Show SMILES CC(c1cnc2ccc(nn12)C(C)=NNC(N)=O)c1c(F)cc2n(C)ncc2c1F |w:13.15|
Show InChI InChI=1S/C19H18F2N8O/c1-9(17-12(20)6-14-11(18(17)21)7-24-28(14)3)15-8-23-16-5-4-13(27-29(15)16)10(2)25-26-19(22)30/h4-9H,1-3H3,(H3,22,26,30)
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99230
PNG
(US8497368, 22)
Show SMILES CC(=NNC(N)=O)c1ccc2ncc(C(O)c3cc4cccnc4cc3F)n2n1 |w:2.2|
Show InChI InChI=1S/C19H16FN7O2/c1-10(24-25-19(21)29)14-4-5-17-23-9-16(27(17)26-14)18(28)12-7-11-3-2-6-22-15(11)8-13(12)20/h2-9,18,28H,1H3,(H3,21,25,29)
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99231
PNG
(US8497368, 23)
Show SMILES CC(=NNC(N)=O)c1ccc2ncc(C(O)c3ccc4ncccc4c3)n2n1 |w:2.2|
Show InChI InChI=1S/C19H17N7O2/c1-11(23-24-19(20)28)14-6-7-17-22-10-16(26(17)25-14)18(27)13-4-5-15-12(9-13)3-2-8-21-15/h2-10,18,27H,1H3,(H3,20,24,28)
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99285
PNG
(US8497368, 77)
Show SMILES CCC(=O)NN=C(C)c1cnc2nnn(Cc3cc4cccnc4cc3F)c2n1 |w:5.4|
Show InChI InChI=1S/C19H17FN8O/c1-3-17(29)25-24-11(2)16-9-22-18-19(23-16)28(27-26-18)10-13-7-12-5-4-6-21-15(12)8-14(13)20/h4-9H,3,10H2,1-2H3,(H,25,29)
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99287
PNG
(US8497368, 79)
Show SMILES CC(=NN1CCNC1=O)c1cnc2nnn(Cc3cc4cccnc4cc3F)c2n1 |w:2.2|
Show InChI InChI=1S/C19H16FN9O/c1-11(26-28-6-5-22-19(28)30)16-9-23-17-18(24-16)29(27-25-17)10-13-7-12-3-2-4-21-15(12)8-14(13)20/h2-4,7-9H,5-6,10H2,1H3,(H,22,30)
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99242
PNG
(US8497368, 34)
Show SMILES CC(=Nn1cc(O)[nH]c1=O)c1ccc2nnc(n2n1)C(F)(F)c1ccc2ncccc2c1 |w:2.2|
Show InChI InChI=1S/C20H14F2N8O2/c1-11(27-29-10-17(31)24-19(29)32)14-6-7-16-25-26-18(30(16)28-14)20(21,22)13-4-5-15-12(9-13)3-2-8-23-15/h2-10,31H,1H3,(H,24,32)/b27-11+
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99247
PNG
(US8497368, 39)
Show SMILES CN(N=C(C)c1ccc2nnc(Cc3ccc4ncccc4c3)n2n1)C(N)=O |w:2.1|
Show InChI InChI=1S/C19H18N8O/c1-12(24-26(2)19(20)28)15-7-8-17-22-23-18(27(17)25-15)11-13-5-6-16-14(10-13)4-3-9-21-16/h3-10H,11H2,1-2H3,(H2,20,28)
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99276
PNG
(US8497368, 68)
Show SMILES CC(c1cnc2ccc(nn12)C(C)=NNC(N)=O)c1cc2cnn(C)c2cc1F |w:13.15|
Show InChI InChI=1S/C19H19FN8O/c1-10(13-6-12-8-23-27(3)16(12)7-14(13)20)17-9-22-18-5-4-15(26-28(17)18)11(2)24-25-19(21)29/h4-10H,1-3H3,(H3,21,25,29)
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99235
PNG
(US8497368, 27)
Show SMILES CC(=NNC(N)=O)c1ccc2ncc(n2n1)C(C)(O)c1cc2cccnc2cc1F |w:2.2|
Show InChI InChI=1S/C20H18FN7O2/c1-11(25-26-19(22)29)15-5-6-18-24-10-17(28(18)27-15)20(2,30)13-8-12-4-3-7-23-16(12)9-14(13)21/h3-10,30H,1-2H3,(H3,22,26,29)
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99266
PNG
(US8497368, 58)
Show SMILES CC(=NNS(C)(=O)=O)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1 |w:2.2|
Show InChI InChI=1S/C17H16N8O2S/c1-11(21-24-28(2,26)27)15-9-19-16-17(20-15)25(23-22-16)10-12-5-6-14-13(8-12)4-3-7-18-14/h3-9,24H,10H2,1-2H3
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99278
PNG
(US8497368, 70)
Show SMILES CC(=NNC(N)=O)c1ccc2ncc(Cc3ccc4n(C)ncc4c3)n2n1 |w:2.2|
Show InChI InChI=1S/C18H18N8O/c1-11(22-23-18(19)27)15-4-6-17-20-10-14(26(17)24-15)8-12-3-5-16-13(7-12)9-21-25(16)2/h3-7,9-10H,8H2,1-2H3,(H3,19,23,27)
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99279
PNG
(US8497368, 71)
Show SMILES CC(c1cnc2ccc(nn12)C(C)=NNC(N)=O)c1ccc2n(C)ncc2c1 |w:13.15|
Show InChI InChI=1S/C19H20N8O/c1-11(13-4-6-16-14(8-13)9-22-26(16)3)17-10-21-18-7-5-15(25-27(17)18)12(2)23-24-19(20)28/h4-11H,1-3H3,(H3,20,24,28)
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99212
PNG
(US8497368, 2)
Show SMILES CCN\N=C(/C)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1
Show InChI InChI=1S/C20H19FN6/c1-3-24-25-13(2)18-6-7-20-23-12-16(27(20)26-18)10-15-9-14-5-4-8-22-19(14)11-17(15)21/h4-9,11-13H,3,10H2,1-2H3
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99215
PNG
(US8497368, 5)
Show SMILES C\C(=N/Nc1ccccn1)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1
Show InChI InChI=1S/C23H18FN7/c1-15(28-29-22-6-2-3-9-26-22)20-7-8-23-27-14-18(31(23)30-20)12-17-11-16-5-4-10-25-21(16)13-19(17)24/h2-11,13-15H,12H2,1H3
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99261
PNG
(US8497368, 53)
Show SMILES CC(=NNC(=O)CN1CCOCC1)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1 |w:2.2|
Show InChI InChI=1S/C22H23N9O2/c1-15(26-27-20(32)14-30-7-9-33-10-8-30)19-12-24-21-22(25-19)31(29-28-21)13-16-4-5-18-17(11-16)3-2-6-23-18/h2-6,11-12H,7-10,13-14H2,1H3,(H,27,32)
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99251
PNG
(US8497368, 43)
Show SMILES CCN(N=C(C)c1ccc2nnc(Cc3c(F)cc4ncccc4c3F)n2n1)C(N)=O |w:3.2|
Show InChI InChI=1S/C20H18F2N8O/c1-3-29(20(23)31)27-11(2)15-6-7-17-25-26-18(30(17)28-15)9-13-14(21)10-16-12(19(13)22)5-4-8-24-16/h4-8,10H,3,9H2,1-2H3,(H2,23,31)
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99243
PNG
(US8497368, 35)
Show SMILES CC(=NN1CCNC1=O)c1ccc2nnc(n2n1)C(F)(F)c1ccc2ncccc2c1 |w:2.2|
Show InChI InChI=1S/C20H16F2N8O/c1-12(27-29-10-9-24-19(29)31)15-6-7-17-25-26-18(30(17)28-15)20(21,22)14-4-5-16-13(11-14)3-2-8-23-16/h2-8,11H,9-10H2,1H3,(H,24,31)
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99234
PNG
(US8497368, 26)
Show SMILES CN(N=C(C)c1ccc2ncc(C(O)c3c(F)cc4ncccc4c3F)n2n1)C(N)=O |w:2.1|
Show InChI InChI=1S/C20H17F2N7O2/c1-10(26-28(2)20(23)31)13-5-6-16-25-9-15(29(16)27-13)19(30)17-12(21)8-14-11(18(17)22)4-3-7-24-14/h3-9,19,30H,1-2H3,(H2,23,31)
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99272
PNG
(US8497368, 64)
Show SMILES CC(=O)NN=C(N)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1 |w:4.3|
Show InChI InChI=1S/C17H15N9O/c1-10(27)22-23-15(18)14-8-20-16-17(21-14)26(25-24-16)9-11-4-5-13-12(7-11)3-2-6-19-13/h2-8H,9H2,1H3,(H2,18,23)(H,22,27)
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99224
PNG
(US8497368, 14)
Show SMILES CCNC(=S)NN=C(C)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1 |w:6.5|
Show InChI InChI=1S/C21H20FN7S/c1-3-23-21(30)27-26-13(2)18-6-7-20-25-12-16(29(20)28-18)10-15-9-14-5-4-8-24-19(14)11-17(15)22/h4-9,11-12H,3,10H2,1-2H3,(H2,23,27,30)
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99289
PNG
(US8497368, 129)
Show SMILES CC(=NNC(N)=O)c1cnc2ncc(Cc3ccc4ncccc4c3)n2n1 |w:2.2|
Show InChI InChI=1S/C18H16N8O/c1-11(23-24-17(19)27)16-10-22-18-21-9-14(26(18)25-16)8-12-4-5-15-13(7-12)3-2-6-20-15/h2-7,9-10H,8H2,1H3,(H3,19,24,27)
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n/an/a 42n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99219
PNG
(US8497368, 9)
Show SMILES CNC(=O)N(C)N=C(C)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1 |w:6.5|
Show InChI InChI=1S/C21H20FN7O/c1-13(26-28(3)21(30)23-2)18-6-7-20-25-12-16(29(20)27-18)10-15-9-14-5-4-8-24-19(14)11-17(15)22/h4-9,11-12H,10H2,1-3H3,(H,23,30)
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Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99236
PNG
(US8497368, 28)
Show SMILES CC(=NNC(N)=O)c1ccc2ncc(n2n1)C(C)(O)c1ccc2ncccc2c1 |w:2.2|
Show InChI InChI=1S/C20H19N7O2/c1-12(24-25-19(21)28)15-7-8-18-23-11-17(27(18)26-15)20(2,29)14-5-6-16-13(10-14)4-3-9-22-16/h3-11,29H,1-2H3,(H3,21,25,28)
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n/an/a 66n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99271
PNG
(US8497368, 63)
Show SMILES CCN(N=C(C)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1)C(N)=O |w:3.2|
Show InChI InChI=1S/C19H19N9O/c1-3-27(19(20)29)25-12(2)16-10-22-17-18(23-16)28(26-24-17)11-13-6-7-15-14(9-13)5-4-8-21-15/h4-10H,3,11H2,1-2H3,(H2,20,29)
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n/an/a 66n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99265
PNG
(US8497368, 57)
Show SMILES CC(=NN1CCNC1=O)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1 |w:2.2|
Show InChI InChI=1S/C19H17N9O/c1-12(25-27-8-7-21-19(27)29)16-10-22-17-18(23-16)28(26-24-17)11-13-4-5-15-14(9-13)3-2-6-20-15/h2-6,9-10H,7-8,11H2,1H3,(H,21,29)
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n/an/a 73n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99258
PNG
(US8497368, 50)
Show SMILES CN(N=C(C)c1ccc2nnc(n2n1)C1(CC1)c1ccc2ncccc2c1)C(N)=O |w:2.1|
Show InChI InChI=1S/C21H20N8O/c1-13(26-28(2)20(22)30)16-7-8-18-24-25-19(29(18)27-16)21(9-10-21)15-5-6-17-14(12-15)4-3-11-23-17/h3-8,11-12H,9-10H2,1-2H3,(H2,22,30)
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n/an/a 77n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99216
PNG
(US8497368, 6)
Show SMILES CC(=NNC(=O)Nc1ccccc1)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1 |w:2.2|
Show InChI InChI=1S/C25H20FN7O/c1-16(30-31-25(34)29-19-7-3-2-4-8-19)22-9-10-24-28-15-20(33(24)32-22)13-18-12-17-6-5-11-27-23(17)14-21(18)26/h2-12,14-15H,13H2,1H3,(H2,29,31,34)
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n/an/a 83n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99262
PNG
(US8497368, 54)
Show SMILES CN1CCN(CC(=O)NN=C(C)c2cnc3nnn(Cc4ccc5ncccc5c4)c3n2)CC1 |w:9.8|
Show InChI InChI=1S/C23H26N10O/c1-16(27-28-21(34)15-32-10-8-31(2)9-11-32)20-13-25-22-23(26-20)33(30-29-22)14-17-5-6-19-18(12-17)4-3-7-24-19/h3-7,12-13H,8-11,14-15H2,1-2H3,(H,28,34)
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n/an/a 119n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99259
PNG
(US8497368, 51)
Show SMILES CC(=NNC(N)=O)c1cnc2ncc(Cc3ccc4ncccc4c3)n2c1 |w:2.2|
Show InChI InChI=1S/C19H17N7O/c1-12(24-25-18(20)27)15-9-22-19-23-10-16(26(19)11-15)8-13-4-5-17-14(7-13)3-2-6-21-17/h2-7,9-11H,8H2,1H3,(H3,20,25,27)
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n/an/a 131n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99232
PNG
(US8497368, 24)
Show SMILES CN(N=C(C)c1ccc2ncc(C(O)c3cc4cccnc4cc3F)n2n1)C(N)=O |w:2.1|
Show InChI InChI=1S/C20H18FN7O2/c1-11(25-27(2)20(22)30)15-5-6-18-24-10-17(28(18)26-15)19(29)13-8-12-4-3-7-23-16(12)9-14(13)21/h3-10,19,29H,1-2H3,(H2,22,30)
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n/an/a 159n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99249
PNG
(US8497368, 41)
Show SMILES CNC(=O)N(C)N=C(C)c1ccc2nnc(Cc3c(F)cc4ncccc4c3F)n2n1 |w:6.5|
Show InChI InChI=1S/C20H18F2N8O/c1-11(27-29(3)20(31)23-2)15-6-7-17-25-26-18(30(17)28-15)9-13-14(21)10-16-12(19(13)22)5-4-8-24-16/h4-8,10H,9H2,1-3H3,(H,23,31)
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n/an/a 185n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99269
PNG
(US8497368, 61)
Show SMILES CNC(=O)NN=C(C)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1 |w:5.4|
Show InChI InChI=1S/C18H17N9O/c1-11(23-25-18(28)19-2)15-9-21-16-17(22-15)27(26-24-16)10-12-5-6-14-13(8-12)4-3-7-20-14/h3-9H,10H2,1-2H3,(H2,19,25,28)
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n/an/a 191n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99244
PNG
(US8497368, 36)
Show SMILES CC(=NNC(=O)CN1CCOCC1)c1ccc2nnc(n2n1)C(F)(F)c1ccc2ncccc2c1 |w:2.2|
Show InChI InChI=1S/C23H22F2N8O2/c1-15(27-29-21(34)14-32-9-11-35-12-10-32)18-6-7-20-28-30-22(33(20)31-18)23(24,25)17-4-5-19-16(13-17)3-2-8-26-19/h2-8,13H,9-12,14H2,1H3,(H,29,34)
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n/an/a 224n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99223
PNG
(US8497368, 13)
Show SMILES CC(=NNS(C)(=O)=O)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1 |w:2.2|
Show InChI InChI=1S/C19H17FN6O2S/c1-12(23-25-29(2,27)28)17-5-6-19-22-11-15(26(19)24-17)9-14-8-13-4-3-7-21-18(13)10-16(14)20/h3-8,10-11,25H,9H2,1-2H3
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n/an/a 250n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99255
PNG
(US8497368, 47)
Show SMILES CC(=NNC(N)=O)c1ccc2nnc(n2n1)C(C)(C)c1ccc2ncccc2c1 |w:2.2|
Show InChI InChI=1S/C20H20N8O/c1-12(23-26-19(21)29)15-8-9-17-24-25-18(28(17)27-15)20(2,3)14-6-7-16-13(11-14)5-4-10-22-16/h4-11H,1-3H3,(H3,21,26,29)
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n/an/a 260n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99214
PNG
(US8497368, 4)
Show SMILES C\C(=N/Nc1ccccc1)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1
Show InChI InChI=1S/C24H19FN6/c1-16(28-29-19-7-3-2-4-8-19)22-9-10-24-27-15-20(31(24)30-22)13-18-12-17-6-5-11-26-23(17)14-21(18)25/h2-12,14-16H,13H2,1H3
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n/an/a 267n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99222
PNG
(US8497368, 12)
Show SMILES C\C(=N/Nc1nc2ccccc2o1)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1
Show InChI InChI=1S/C25H18FN7O/c1-15(30-31-25-29-21-6-2-3-7-23(21)34-25)20-8-9-24-28-14-18(33(24)32-20)12-17-11-16-5-4-10-27-22(16)13-19(17)26/h2-11,13-15H,12H2,1H3
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n/an/a 590n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99270
PNG
(US8497368, 62)
Show SMILES CNC(=O)N(C)N=C(C)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1 |w:6.5|
Show InChI InChI=1S/C19H19N9O/c1-12(25-27(3)19(29)20-2)16-10-22-17-18(23-16)28(26-24-17)11-13-6-7-15-14(9-13)5-4-8-21-15/h4-10H,11H2,1-3H3,(H,20,29)
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n/an/a 685n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99225
PNG
(US8497368, 15)
Show SMILES CC(=NNC(=S)NCc1ccccc1)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1 |w:2.2|
Show InChI InChI=1S/C26H22FN7S/c1-17(31-32-26(35)30-15-18-6-3-2-4-7-18)23-9-10-25-29-16-21(34(25)33-23)13-20-12-19-8-5-11-28-24(19)14-22(20)27/h2-12,14,16H,13,15H2,1H3,(H2,30,32,35)
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n/an/a 932n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99217
PNG
(US8497368, 7)
Show SMILES CC(=NNC(=O)Nc1ccc(Cl)cc1)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1 |w:2.2|
Show InChI InChI=1S/C25H19ClFN7O/c1-15(31-32-25(35)30-19-6-4-18(26)5-7-19)22-8-9-24-29-14-20(34(24)33-22)12-17-11-16-3-2-10-28-23(16)13-21(17)27/h2-11,13-14H,12H2,1H3,(H2,30,32,35)
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n/an/a 2.45E+3n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM99256
PNG
(US8497368, 48)
Show SMILES CN(N=C(C)c1ccc2nnc(n2n1)C(C)(C)c1ccc2ncccc2c1)C(N)=O |w:2.1|
Show InChI InChI=1S/C21H22N8O/c1-13(26-28(4)20(22)30)16-9-10-18-24-25-19(29(18)27-16)21(2,3)15-7-8-17-14(12-15)6-5-11-23-17/h5-12H,1-4H3,(H2,22,30)
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n/an/a 2.98E+3n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...

US Patent US8497368 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DN7
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%