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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Complement factor B (Homo sapiens (Human)) | BDBM181732 (US9676728, 5 b (±)-2-(2,2,2-Trifluoro-1-(2-methoxy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet  | PC cid PC sid UniChem | US Patent | n/a | n/a | 23 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi... | US Patent US9676728 (2017) BindingDB Entry DOI: 10.7270/Q2QN64W8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Complement factor B (Homo sapiens (Human)) | BDBM182861 (US9676728, 11-B b (±)-2-(2,2,2-Trifluoro-1-methoxy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 55 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description Recombinant human factor B (expressed in drosophila cells and purified using standard methods) labeled with biotin (10 nM), europium-labeled streptav... | US Patent US9676728 (2017) BindingDB Entry DOI: 10.7270/Q2QN64W8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Complement factor B (Homo sapiens (Human)) | BDBM181734 (US9676728, 6-A (±)-2-(2,2,2-Trifluoro-1-(2-methoxy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 380 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi... | US Patent US9676728 (2017) BindingDB Entry DOI: 10.7270/Q2QN64W8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Complement factor B (Homo sapiens (Human)) | BDBM181724 (US9676728, 3-B (±)-2-(2,2,2-Trifluoro-1-hydroxy-1-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 390 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi... | US Patent US9676728 (2017) BindingDB Entry DOI: 10.7270/Q2QN64W8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Complement factor B (Homo sapiens (Human)) | BDBM182859 (US9676728, 10-C (±)-2-(1-(5-Cyano-1H-benzo[d]imida...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 470 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description Recombinant human factor B (expressed in drosophila cells and purified using standard methods) labeled with biotin (10 nM), europium-labeled streptav... | US Patent US9676728 (2017) BindingDB Entry DOI: 10.7270/Q2QN64W8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Complement factor B (Homo sapiens (Human)) | BDBM181709 (US9676728, 2-C (±)-2-(1-Hydroxy-1-(2-methoxy-4,6-d...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.45E+3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi... | US Patent US9676728 (2017) BindingDB Entry DOI: 10.7270/Q2QN64W8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Complement factor B (Homo sapiens (Human)) | BDBM182856 (US9676728, 9-C (±)-2-(Amino(cyclopropyl)(2-methoxy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi... | US Patent US9676728 (2017) BindingDB Entry DOI: 10.7270/Q2QN64W8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Complement factor B (Homo sapiens (Human)) | BDBM181740 (US9676728, 6-D (±)-2-(1-Amino-2,2,2-trifluoro-1-(2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.57E+3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi... | US Patent US9676728 (2017) BindingDB Entry DOI: 10.7270/Q2QN64W8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Complement factor B (Homo sapiens (Human)) | BDBM181732 (US9676728, 5 b (±)-2-(2,2,2-Trifluoro-1-(2-methoxy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi... | US Patent US9676728 (2017) BindingDB Entry DOI: 10.7270/Q2QN64W8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Complement factor B (Homo sapiens (Human)) | BDBM181736 (US9676728, 6-B (±)-2-(1-(3-Chloro-6-methoxy-2,4-di...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.98E+3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi... | US Patent US9676728 (2017) BindingDB Entry DOI: 10.7270/Q2QN64W8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Complement factor B (Homo sapiens (Human)) | BDBM181738 (US9676728, 6-C (±)-2-(2,2,2-Trifluoro-1-(2-methoxy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.13E+3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi... | US Patent US9676728 (2017) BindingDB Entry DOI: 10.7270/Q2QN64W8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Complement factor B (Homo sapiens (Human)) | BDBM181675 (US9676728, 1-C (±)-2-(Hydroxy(2-methoxy-4,6-dimeth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.75E+3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi... | US Patent US9676728 (2017) BindingDB Entry DOI: 10.7270/Q2QN64W8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Complement factor B (Homo sapiens (Human)) | BDBM182228 (US9676728, 8-B (±)-2-(1-Amino-1-(2-methoxy-4,6-dim...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.90E+3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi... | US Patent US9676728 (2017) BindingDB Entry DOI: 10.7270/Q2QN64W8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Complement factor B (Homo sapiens (Human)) | BDBM181742 (US9676728, 6-E (±)-2-(1-(3-Bromo-6-methoxy-2,4-dim...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description Recombinant human factor B (expressed in drosophila cells and purified using standard methods) labeled with biotin (10 nM), europium-labeled streptav... | US Patent US9676728 (2017) BindingDB Entry DOI: 10.7270/Q2QN64W8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Complement factor B (Homo sapiens (Human)) | BDBM182103 (US9676728, 7-D (±)-2-(Amino(2-methoxy-4,6-dimethyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.70E+3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi... | US Patent US9676728 (2017) BindingDB Entry DOI: 10.7270/Q2QN64W8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Complement factor B (Homo sapiens (Human)) | BDBM182866 (US9676728, 12-D (B) (±)-2-(1-(2,6-dimethoxy-4-meth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.11E+4 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi... | US Patent US9676728 (2017) BindingDB Entry DOI: 10.7270/Q2QN64W8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Complement factor B (Homo sapiens (Human)) | BDBM182865 (US9676728, 12-D (A) (±)-2-((2,6-Dimethoxy-4-methyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.39E+4 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi... | US Patent US9676728 (2017) BindingDB Entry DOI: 10.7270/Q2QN64W8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Complement factor B (Homo sapiens (Human)) | BDBM182861 (US9676728, 11-B b (±)-2-(2,2,2-Trifluoro-1-methoxy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.11E+4 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description Recombinant human factor B (expressed in drosophila cells and purified using standard methods) labeled with biotin (10 nM), europium-labeled streptav... | US Patent US9676728 (2017) BindingDB Entry DOI: 10.7270/Q2QN64W8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Complement factor B (Homo sapiens (Human)) | BDBM181729 (US9676728, 4 (±)-2-(1-(3-bromo-6-methoxy-2,4-dimet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 9.89E+4 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description Recombinant human factor B (expressed in drosophila cells and purified using standard methods) labeled with biotin (10 nM), europium-labeled streptav... | US Patent US9676728 (2017) BindingDB Entry DOI: 10.7270/Q2QN64W8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
