| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein phosphatase PP1-gamma catalytic subunit |
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| Ligand | BDBM50177317 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_331861 (CHEMBL865879) |
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| IC50 | 35200±n/a nM |
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| Citation |  Cho, SY; Baek, JY; Han, SS; Kang, SK; Ha, JD; Ahn, JH; Lee, JD; Kim, KR; Cheon, HG; Rhee, SD; Yang, SD; Yon, GH; Pak, CS; Choi, JK PTP-1B inhibitors: cyclopenta[d][1,2]-oxazine derivatives. Bioorg Med Chem Lett16:499-502 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein phosphatase PP1-gamma catalytic subunit |
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| Name: | Serine/threonine-protein phosphatase PP1-gamma catalytic subunit |
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| Synonyms: | PP1G_HUMAN | PPP1CC | Serine/threonine protein phosphatase PP1-gamma catalytic subunit |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36983.39 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_473188 |
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| Residue: | 323 |
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| Sequence: | MADLDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLK
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHD
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAE
KKKPNATRPVTPPRGMITKQAKK
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| BDBM50177317 |
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| n/a |
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| Name | BDBM50177317 |
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| Synonyms: | 2-(4-(7-(4-methoxybenzoyl)cyclopenta[d][1,2]oxazin-4-yl)phenoxy)acetic acid | CHEMBL201662 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H17NO6 |
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| Mol. Mass. | 403.3842 |
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| SMILES | COc1ccc(cc1)C(=O)c1ccc2c(nocc12)-c1ccc(OCC(O)=O)cc1 |
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| Structure | 
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