Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human)) | BDBM20461 ((6E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL | Assay Description Binding affinity to human recombinant TRPV1 | Bioorg Med Chem Lett 20: 7137-41 (2010) Article DOI: 10.1016/j.bmcl.2010.09.023 BindingDB Entry DOI: 10.7270/Q29W0FQ5 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human)) | BDBM50052442 ((4-Hydroxy-3-methoxy-phenyl)-acetic acid (2R,3S,3a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL | Assay Description Binding affinity to human recombinant TRPV1 | Bioorg Med Chem Lett 20: 7137-41 (2010) Article DOI: 10.1016/j.bmcl.2010.09.023 BindingDB Entry DOI: 10.7270/Q29W0FQ5 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat)) | BDBM50254419 (CHEMBL511391 | N2-(2,6-dichlorophenyl)-N7-(4-(pyrr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL | Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux | Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat)) | BDBM50254080 ((3,5-dichloro-4-(7-(4-(trifluoromethyl)phenylamino...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL | Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux | Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50174990 (CHEMBL3809293) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutical Companies of Johnson& Johnson, L.L.C. Curated by ChEMBL | Assay Description Apparent inhibition of recombinant human FAAH expressed in SK-N-MC cells assessed as [3H]-anandamide hydrolysis after 1 hr by liquid scintillation an... | Bioorg Med Chem Lett 26: 3109-14 (2016) Article DOI: 10.1016/j.bmcl.2016.05.001 BindingDB Entry DOI: 10.7270/Q25B04F3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat)) | BDBM50254077 (CHEMBL517566 | N2-(2,6-dichlorophenyl)-N5-isobutyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL | Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux | Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat)) | BDBM50254325 (CHEMBL469302 | N7-(4-tert-butylphenyl)-N2-(2,6-dic...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL | Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux | Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50174997 (CHEMBL3809683) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutical Companies of Johnson& Johnson, L.L.C. Curated by ChEMBL | Assay Description Apparent inhibition of recombinant human FAAH expressed in SK-N-MC cells assessed as [3H]-anandamide hydrolysis after 1 hr by liquid scintillation an... | Bioorg Med Chem Lett 26: 3109-14 (2016) Article DOI: 10.1016/j.bmcl.2016.05.001 BindingDB Entry DOI: 10.7270/Q25B04F3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human)) | BDBM50254419 (CHEMBL511391 | N2-(2,6-dichlorophenyl)-N7-(4-(pyrr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL | Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux | Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human)) | BDBM50254080 ((3,5-dichloro-4-(7-(4-(trifluoromethyl)phenylamino...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL | Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux | Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50448310 (CHEMBL3121143) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutical Companies of Johnson& Johnson Curated by ChEMBL | Assay Description Inhibition of human FAAH | Bioorg Med Chem Lett 24: 1280-4 (2014) Article DOI: 10.1016/j.bmcl.2014.01.064 BindingDB Entry DOI: 10.7270/Q2TH8P67 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50174984 (CHEMBL3809841) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutical Companies of Johnson& Johnson, L.L.C. Curated by ChEMBL | Assay Description Apparent inhibition of recombinant human FAAH expressed in SK-N-MC cells assessed as [3H]-anandamide hydrolysis after 1 hr by liquid scintillation an... | Bioorg Med Chem Lett 26: 3109-14 (2016) Article DOI: 10.1016/j.bmcl.2016.05.001 BindingDB Entry DOI: 10.7270/Q25B04F3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50394620 (CHEMBL2164602) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutical Companies of Johnson& Johnson, L.L.C. Curated by ChEMBL | Assay Description Apparent inhibition of recombinant human FAAH expressed in SK-N-MC cells assessed as [3H]-anandamide hydrolysis after 1 hr by liquid scintillation an... | Bioorg Med Chem Lett 26: 3109-14 (2016) Article DOI: 10.1016/j.bmcl.2016.05.001 BindingDB Entry DOI: 10.7270/Q25B04F3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50350557 (CHEMBL1812715) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutical Companies of Johnson& Johnson Curated by ChEMBL | Assay Description Inhibition of human FAAH | Bioorg Med Chem Lett 24: 1280-4 (2014) Article DOI: 10.1016/j.bmcl.2014.01.064 BindingDB Entry DOI: 10.7270/Q2TH8P67 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat)) | BDBM50254154 (CHEMBL468470 | N2-(2-chloro-6-methylphenyl)-N7-(4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL | Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux | Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat)) | BDBM50254326 (2-(4-(2-(2,6-dichlorophenylamino)thiazolo[5,4-d]py...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL | Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux | Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human)) | BDBM50254077 (CHEMBL517566 | N2-(2,6-dichlorophenyl)-N5-isobutyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL | Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux | Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat)) | BDBM50254421 (CHEMBL465990 | N7-(3-chloro-4-(trifluoromethyl)phe...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL | Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux | Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat)) | BDBM50560624 (CHEMBL4747373) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of rat FAAH1 incubated for 60 mins | Citation and Details Article DOI: 10.1016/j.bmcl.2020.127463 BindingDB Entry DOI: 10.7270/Q2R78JXM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50174988 (CHEMBL3808688) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutical Companies of Johnson& Johnson, L.L.C. Curated by ChEMBL | Assay Description Apparent inhibition of recombinant human FAAH expressed in SK-N-MC cells assessed as [3H]-anandamide hydrolysis after 1 hr by liquid scintillation an... | Bioorg Med Chem Lett 26: 3109-14 (2016) Article DOI: 10.1016/j.bmcl.2016.05.001 BindingDB Entry DOI: 10.7270/Q25B04F3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50560624 (CHEMBL4747373) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human FAAH1 incubated for 60 mins | Citation and Details Article DOI: 10.1016/j.bmcl.2020.127463 BindingDB Entry DOI: 10.7270/Q2R78JXM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50402695 (CHEMBL2207356) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutical Companies of Johnson& Johnson, L.L.C. Curated by ChEMBL | Assay Description Apparent inhibition of recombinant human FAAH expressed in SK-N-MC cells assessed as [3H]-anandamide hydrolysis after 1 hr by liquid scintillation an... | Bioorg Med Chem Lett 26: 3109-14 (2016) Article DOI: 10.1016/j.bmcl.2016.05.001 BindingDB Entry DOI: 10.7270/Q25B04F3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human)) | BDBM50254078 (CHEMBL460373 | N5-(cyclopropylmethyl)-N2-(2,6-dich...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL | Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux | Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat)) | BDBM50254136 (CHEMBL469297 | N2-(2,6-dichlorophenyl)-N7-(4-(trif...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL | Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux | Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human)) | BDBM50254421 (CHEMBL465990 | N7-(3-chloro-4-(trifluoromethyl)phe...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL | Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux | Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat)) | BDBM50254078 (CHEMBL460373 | N5-(cyclopropylmethyl)-N2-(2,6-dich...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL | Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux | Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat)) | BDBM50254376 (CHEMBL467851 | N2-(2,6-dichlorophenyl)-N7-(4-(meth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL | Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux | Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat)) | BDBM50254324 (CHEMBL512298 | N2-(2,6-dichlorophenyl)-N7-(4-isopr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL | Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux | Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat)) | BDBM50350557 (CHEMBL1812715) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutical Companies of Johnson& Johnson Curated by ChEMBL | Assay Description Inhibition of rat FAAH | Bioorg Med Chem Lett 24: 1280-4 (2014) Article DOI: 10.1016/j.bmcl.2014.01.064 BindingDB Entry DOI: 10.7270/Q2TH8P67 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50448297 (CHEMBL3121113) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutical Companies of Johnson& Johnson Curated by ChEMBL | Assay Description Inhibition of human FAAH | Bioorg Med Chem Lett 24: 1280-4 (2014) Article DOI: 10.1016/j.bmcl.2014.01.064 BindingDB Entry DOI: 10.7270/Q2TH8P67 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50448337 (CHEMBL3121116) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutical Companies of Johnson& Johnson Curated by ChEMBL | Assay Description Inhibition of human FAAH | Bioorg Med Chem Lett 24: 1280-4 (2014) Article DOI: 10.1016/j.bmcl.2014.01.064 BindingDB Entry DOI: 10.7270/Q2TH8P67 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50174991 (CHEMBL3809071) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutical Companies of Johnson& Johnson, L.L.C. Curated by ChEMBL | Assay Description Apparent inhibition of recombinant human FAAH expressed in SK-N-MC cells assessed as [3H]-anandamide hydrolysis after 1 hr by liquid scintillation an... | Bioorg Med Chem Lett 26: 3109-14 (2016) Article DOI: 10.1016/j.bmcl.2016.05.001 BindingDB Entry DOI: 10.7270/Q25B04F3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat)) | BDBM50560652 (CHEMBL4777574) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of rat FAAH1 incubated for 60 mins | Citation and Details Article DOI: 10.1016/j.bmcl.2020.127463 BindingDB Entry DOI: 10.7270/Q2R78JXM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat)) | BDBM50254136 (CHEMBL469297 | N2-(2,6-dichlorophenyl)-N7-(4-(trif...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL | Assay Description Displacement of [3H]RTX from rat TRPV1 expressed in HEK293 cells | Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat)) | BDBM50254322 (CHEMBL467007 | N2-(2,6-dichlorophenyl)-N7-(6-(trif...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL | Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux | Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat)) | BDBM50560616 (CHEMBL4755710) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of rat FAAH1 incubated for 60 mins | Citation and Details Article DOI: 10.1016/j.bmcl.2020.127463 BindingDB Entry DOI: 10.7270/Q2R78JXM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50174994 (CHEMBL3809332) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutical Companies of Johnson& Johnson, L.L.C. Curated by ChEMBL | Assay Description Apparent inhibition of recombinant human FAAH expressed in SK-N-MC cells assessed as [3H]-anandamide hydrolysis after 1 hr by liquid scintillation an... | Bioorg Med Chem Lett 26: 3109-14 (2016) Article DOI: 10.1016/j.bmcl.2016.05.001 BindingDB Entry DOI: 10.7270/Q25B04F3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50448317 (CHEMBL3121136) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutical Companies of Johnson& Johnson Curated by ChEMBL | Assay Description Inhibition of human FAAH | Bioorg Med Chem Lett 24: 1280-4 (2014) Article DOI: 10.1016/j.bmcl.2014.01.064 BindingDB Entry DOI: 10.7270/Q2TH8P67 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human)) | BDBM50254376 (CHEMBL467851 | N2-(2,6-dichlorophenyl)-N7-(4-(meth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL | Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux | Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat)) | BDBM50560621 (CHEMBL4758524) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of rat FAAH1 incubated for 60 mins | Citation and Details Article DOI: 10.1016/j.bmcl.2020.127463 BindingDB Entry DOI: 10.7270/Q2R78JXM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat)) | BDBM50447674 (CHEMBL3112940) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, L.L.C. Curated by ChEMBL | Assay Description Inhibition of rat FAAH after 60 mins | Bioorg Med Chem Lett 24: 737-41 (2014) Article DOI: 10.1016/j.bmcl.2013.12.113 BindingDB Entry DOI: 10.7270/Q2CN75DP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50448334 (CHEMBL3121119) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutical Companies of Johnson& Johnson Curated by ChEMBL | Assay Description Inhibition of human FAAH | Bioorg Med Chem Lett 24: 1280-4 (2014) Article DOI: 10.1016/j.bmcl.2014.01.064 BindingDB Entry DOI: 10.7270/Q2TH8P67 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat)) | BDBM50448337 (CHEMBL3121116) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutical Companies of Johnson& Johnson Curated by ChEMBL | Assay Description Inhibition of rat FAAH | Bioorg Med Chem Lett 24: 1280-4 (2014) Article DOI: 10.1016/j.bmcl.2014.01.064 BindingDB Entry DOI: 10.7270/Q2TH8P67 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat)) | BDBM50402695 (CHEMBL2207356) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutical Companies of Johnson& Johnson, L.L.C. Curated by ChEMBL | Assay Description Apparent inhibition of recombinant rat FAAH expressed in SK-N-MC cells assessed as [3H]-anandamide hydrolysis after 1 hr by liquid scintillation anal... | Bioorg Med Chem Lett 26: 3109-14 (2016) Article DOI: 10.1016/j.bmcl.2016.05.001 BindingDB Entry DOI: 10.7270/Q25B04F3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat)) | BDBM50254153 (CHEMBL511589 | N2-(2,6-dimethylphenyl)-N7-(4-(trif...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL | Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux | Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human)) | BDBM50331116 (2-morpholino-N-(4-(trifluoromethyl)phenyl)-7-(3-(t...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL | Assay Description Antagonist activity at human recombinant TRPV1 assessed as inhibition of capsaicin-induced in intracellular calcium levels by cell-based FLIPR assay | Bioorg Med Chem Lett 20: 7137-41 (2010) Article DOI: 10.1016/j.bmcl.2010.09.023 BindingDB Entry DOI: 10.7270/Q29W0FQ5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human)) | BDBM50331116 (2-morpholino-N-(4-(trifluoromethyl)phenyl)-7-(3-(t...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL | Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced intracellular Ca2+ level by FLIPR assay | Bioorg Med Chem Lett 20: 7142-6 (2010) Article DOI: 10.1016/j.bmcl.2010.09.006 BindingDB Entry DOI: 10.7270/Q26Q1XH0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat)) | BDBM50254136 (CHEMBL469297 | N2-(2,6-dichlorophenyl)-N7-(4-(trif...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL | Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of low pH-induced calcium influx | Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50394629 (CHEMBL2164596 | US9169224, 60) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutical Companies of Johnson& Johnson, L.L.C. Curated by ChEMBL | Assay Description Apparent inhibition of recombinant human FAAH expressed in SK-N-MC cells assessed as [3H]-anandamide hydrolysis after 1 hr by liquid scintillation an... | Bioorg Med Chem Lett 26: 3109-14 (2016) Article DOI: 10.1016/j.bmcl.2016.05.001 BindingDB Entry DOI: 10.7270/Q25B04F3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat)) | BDBM50448334 (CHEMBL3121119) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutical Companies of Johnson& Johnson Curated by ChEMBL | Assay Description Inhibition of rat FAAH | Bioorg Med Chem Lett 24: 1280-4 (2014) Article DOI: 10.1016/j.bmcl.2014.01.064 BindingDB Entry DOI: 10.7270/Q2TH8P67 | |||||||||||
More data for this Ligand-Target Pair |
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