BindingDB PrimarySearch

Found 351 hits with Last Name = 'engel' and Initial = 'c'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cruzipain (Trypanosoma cruzi)	BDBM50306596 (3-(4-((S)-4-methyl-2-(quinolin-6-ylmethylamino)pen...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi cruzain				J Med Chem 53: 1763-73 (2010) Article DOI: 10.1021/jm901633v BindingDB Entry DOI: 10.7270/Q21N8172
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM50306600 (3-(4-((S)-1-cyclopentyl-1-(quinolin-6-ylmethylamin...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi cruzain				J Med Chem 53: 1763-73 (2010) Article DOI: 10.1021/jm901633v BindingDB Entry DOI: 10.7270/Q21N8172
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM50306598 (3-(4-((S)-1-cyclobutyl-1-(quinolin-6-ylmethylamino...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi cruzain				J Med Chem 53: 1763-73 (2010) Article DOI: 10.1021/jm901633v BindingDB Entry DOI: 10.7270/Q21N8172
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM50306597 (3-(4-((S)-4-methyl-2-(quinolin-6-ylmethylamino)pen...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi cruzain				J Med Chem 53: 1763-73 (2010) Article DOI: 10.1021/jm901633v BindingDB Entry DOI: 10.7270/Q21N8172
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM50306599 (3-(4-((S)-1-cyclobutyl-1-(quinolin-6-ylmethylamino...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi cruzain				J Med Chem 53: 1763-73 (2010) Article DOI: 10.1021/jm901633v BindingDB Entry DOI: 10.7270/Q21N8172
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM50306592 (3-(4-((S)-3-methyl-2-(quinolin-6-ylmethylamino)but...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi cruzain				J Med Chem 53: 1763-73 (2010) Article DOI: 10.1021/jm901633v BindingDB Entry DOI: 10.7270/Q21N8172
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50128869 (2,2-Dichloro-N-chrysen-6-yl-acetamide \| CHEMBL8805...) Show SMILES ClC(Cl)C(=O)Nc1cc2c3ccccc3ccc2c2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Connecticut Curated by ChEMBL					Assay Description Kinetic inhibition constant of compound with Trypanosoma cruzi Hypoxanthine Phosphoribosyltransferase (HPRT)				J Med Chem 46: 2548-50 (2003) Article DOI: 10.1021/jm030061i BindingDB Entry DOI: 10.7270/Q2CF9PGG
University of Connecticut Curated by ChEMBL					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50128871 (CHEMBL313154 \| Chrysen-6-ylamine) Show SMILES Nc1cc2c3ccccc3ccc2c2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Connecticut Curated by ChEMBL					Assay Description Kinetic inhibition constant of compound with Trypanosoma cruzi Hypoxanthine Phosphoribosyltransferase (HPRT)				J Med Chem 46: 2548-50 (2003) Article DOI: 10.1021/jm030061i BindingDB Entry DOI: 10.7270/Q2CF9PGG
University of Connecticut Curated by ChEMBL					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM50306595 (3-(4-((S)-1-cyclopropyl-1-(quinolin-6-ylmethylamin...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	940	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi cruzain				J Med Chem 53: 1763-73 (2010) Article DOI: 10.1021/jm901633v BindingDB Entry DOI: 10.7270/Q21N8172
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM50306593 (3-(4-((S)-3-methyl-2-(quinolin-6-ylmethylamino)but...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.04E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi cruzain				J Med Chem 53: 1763-73 (2010) Article DOI: 10.1021/jm901633v BindingDB Entry DOI: 10.7270/Q21N8172
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM50306601 (3-(4-((S)-1-cyclohexyl-1-(quinolin-6-ylmethylamino...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.22E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi cruzain				J Med Chem 53: 1763-73 (2010) Article DOI: 10.1021/jm901633v BindingDB Entry DOI: 10.7270/Q21N8172
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50128867 (3,5-diphenyl-4'-methyl-2-nitrobiphenyl \| CHEMBL875...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Connecticut Curated by ChEMBL					Assay Description Kinetic inhibition constant of compound with Trypanosoma cruzi Hypoxanthine Phosphoribosyltransferase (HPRT)				J Med Chem 46: 2548-50 (2003) Article DOI: 10.1021/jm030061i BindingDB Entry DOI: 10.7270/Q2CF9PGG
University of Connecticut Curated by ChEMBL					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50128866 (2-(2,4,7-Trinitro-fluoren-9-ylidene)-malononitrile...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Connecticut Curated by ChEMBL					Assay Description Kinetic inhibition constant of compound with Trypanosoma cruzi Hypoxanthine Phosphoribosyltransferase (HPRT)				J Med Chem 46: 2548-50 (2003) Article DOI: 10.1021/jm030061i BindingDB Entry DOI: 10.7270/Q2CF9PGG
University of Connecticut Curated by ChEMBL					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50128872 (6-Fluoro-chrysene \| CHEMBL83242) Show SMILES Fc1cc2c3ccccc3ccc2c2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Connecticut Curated by ChEMBL					Assay Description Kinetic inhibition constant of compound with Trypanosoma cruzi Hypoxanthine Phosphoribosyltransferase (HPRT)				J Med Chem 46: 2548-50 (2003) Article DOI: 10.1021/jm030061i BindingDB Entry DOI: 10.7270/Q2CF9PGG
University of Connecticut Curated by ChEMBL					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50128866 (2-(2,4,7-Trinitro-fluoren-9-ylidene)-malononitrile...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Connecticut Curated by ChEMBL					Assay Description Kinetic inhibition constant of compound with human Hypoxanthine Phosphoribosyltransferase (HPRT)				J Med Chem 46: 2548-50 (2003) Article DOI: 10.1021/jm030061i BindingDB Entry DOI: 10.7270/Q2CF9PGG
University of Connecticut Curated by ChEMBL					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50128865 (6-Nitro-chrysene \| CHEMBL82858) Show SMILES [O-][N+](=O)c1cc2c3ccccc3ccc2c2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Connecticut Curated by ChEMBL					Assay Description Kinetic inhibition constant of compound with Trypanosoma cruzi Hypoxanthine Phosphoribosyltransferase (HPRT)				J Med Chem 46: 2548-50 (2003) Article DOI: 10.1021/jm030061i BindingDB Entry DOI: 10.7270/Q2CF9PGG
University of Connecticut Curated by ChEMBL					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM50306594 (3-(4-((S)-3-methyl-2-(quinolin-6-ylmethylamino)but...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.76E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi cruzain				J Med Chem 53: 1763-73 (2010) Article DOI: 10.1021/jm901633v BindingDB Entry DOI: 10.7270/Q21N8172
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50128870 (CHEMBL85685 \| chrysene) Show SMILES c1ccc2c(c1)ccc1c3ccccc3ccc21 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	8.98E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Connecticut Curated by ChEMBL					Assay Description Kinetic inhibition constant of compound with Trypanosoma cruzi Hypoxanthine Phosphoribosyltransferase (HPRT)				J Med Chem 46: 2548-50 (2003) Article DOI: 10.1021/jm030061i BindingDB Entry DOI: 10.7270/Q2CF9PGG
University of Connecticut Curated by ChEMBL					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50128867 (3,5-diphenyl-4'-methyl-2-nitrobiphenyl \| CHEMBL875...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.09E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Connecticut Curated by ChEMBL					Assay Description Kinetic inhibition constant of compound with human Hypoxanthine Phosphoribosyltransferase (HPRT)				J Med Chem 46: 2548-50 (2003) Article DOI: 10.1021/jm030061i BindingDB Entry DOI: 10.7270/Q2CF9PGG
University of Connecticut Curated by ChEMBL					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50128868 (5-(2,4-Dichloro-phenoxy)-3-(2-fluoro-phenyl)-[1,2,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	1.18E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Connecticut Curated by ChEMBL					Assay Description Kinetic inhibition constant of compound with Trypanosoma cruzi Hypoxanthine Phosphoribosyltransferase (HPRT)				J Med Chem 46: 2548-50 (2003) Article DOI: 10.1021/jm030061i BindingDB Entry DOI: 10.7270/Q2CF9PGG
University of Connecticut Curated by ChEMBL					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50128867 (3,5-diphenyl-4'-methyl-2-nitrobiphenyl \| CHEMBL875...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.39E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Connecticut Curated by ChEMBL					Assay Description Kinetic inhibition constant of compound with bacterial Hypoxanthine Phosphoribosyltransferase (HPRT)				J Med Chem 46: 2548-50 (2003) Article DOI: 10.1021/jm030061i BindingDB Entry DOI: 10.7270/Q2CF9PGG
University of Connecticut Curated by ChEMBL					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50128869 (2,2-Dichloro-N-chrysen-6-yl-acetamide \| CHEMBL8805...) Show SMILES ClC(Cl)C(=O)Nc1cc2c3ccccc3ccc2c2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Connecticut Curated by ChEMBL					Assay Description Kinetic inhibition constant of compound with human Hypoxanthine Phosphoribosyltransferase (HPRT)				J Med Chem 46: 2548-50 (2003) Article DOI: 10.1021/jm030061i BindingDB Entry DOI: 10.7270/Q2CF9PGG
University of Connecticut Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-aminolevulinic acid dehydratase (Escherichia coli)	BDBM82204 (Substrate analogue, 28) Show SMILES COC(=O)CCC(=O)NCC(=O)CCN(=O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	2.00E+4	-27.9	n/a	n/a	n/a	n/a	n/a	8.1	37
University of Neuchâtel					Assay Description The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent).				Chembiochem 2: 343-54 (2001) Article DOI: 10.1002/1439-7633(20010504)2 BindingDB Entry DOI: 10.7270/Q29Z93CN
University of Neuchâtel					More data for this Ligand-Target Pair
Delta-aminolevulinic acid dehydratase (Escherichia coli)	BDBM82199 (Substrate analogue, 18) Show SMILES FCC(=O)CCN(=O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	2.10E+4	-27.8	n/a	n/a	n/a	n/a	n/a	8.1	37
University of Neuchâtel					Assay Description The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent).				Chembiochem 2: 343-54 (2001) Article DOI: 10.1002/1439-7633(20010504)2 BindingDB Entry DOI: 10.7270/Q29Z93CN
University of Neuchâtel					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50128869 (2,2-Dichloro-N-chrysen-6-yl-acetamide \| CHEMBL8805...) Show SMILES ClC(Cl)C(=O)Nc1cc2c3ccccc3ccc2c2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Connecticut Curated by ChEMBL					Assay Description Kinetic inhibition constant of compound with bacterial Hypoxanthine Phosphoribosyltransferase (HPRT)				J Med Chem 46: 2548-50 (2003) Article DOI: 10.1021/jm030061i BindingDB Entry DOI: 10.7270/Q2CF9PGG
University of Connecticut Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-aminolevulinic acid dehydratase (Escherichia coli)	BDBM82198 (Substrate analogue, 17) Show SMILES CC(=O)CCN(=O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Patents	Article PubMed	2.80E+4	-27.0	n/a	n/a	n/a	n/a	n/a	8.1	37
University of Neuchâtel					Assay Description The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent).				Chembiochem 2: 343-54 (2001) Article DOI: 10.1002/1439-7633(20010504)2 BindingDB Entry DOI: 10.7270/Q29Z93CN
University of Neuchâtel					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50128868 (5-(2,4-Dichloro-phenoxy)-3-(2-fluoro-phenyl)-[1,2,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	2.88E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Connecticut Curated by ChEMBL					Assay Description Kinetic inhibition constant of compound with human Hypoxanthine Phosphoribosyltransferase (HPRT)				J Med Chem 46: 2548-50 (2003) Article DOI: 10.1021/jm030061i BindingDB Entry DOI: 10.7270/Q2CF9PGG
University of Connecticut Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-aminolevulinic acid dehydratase (Escherichia coli)	BDBM82205 (Substrate analogue, 29) Show SMILES O=C(CCN(=O)=O)CNC(=O)CCN(=O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	3.00E+4	-26.9	n/a	n/a	n/a	n/a	n/a	8.1	37
University of Neuchâtel					Assay Description The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent).				Chembiochem 2: 343-54 (2001) Article DOI: 10.1002/1439-7633(20010504)2 BindingDB Entry DOI: 10.7270/Q29Z93CN
University of Neuchâtel					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50128868 (5-(2,4-Dichloro-phenoxy)-3-(2-fluoro-phenyl)-[1,2,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	4.81E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Connecticut Curated by ChEMBL					Assay Description Kinetic inhibition constant of compound with bacterial Hypoxanthine Phosphoribosyltransferase (HPRT)				J Med Chem 46: 2548-50 (2003) Article DOI: 10.1021/jm030061i BindingDB Entry DOI: 10.7270/Q2CF9PGG
University of Connecticut Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-aminolevulinic acid dehydratase (Escherichia coli)	BDBM82192 (Substrate analogue, 9) Show SMILES OC(=O)CCC(=O)CF Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	DrugBank MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	8.50E+4	-24.2	n/a	n/a	n/a	n/a	n/a	8.1	37
University of Neuchâtel					Assay Description The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent).				Chembiochem 2: 343-54 (2001) Article DOI: 10.1002/1439-7633(20010504)2 BindingDB Entry DOI: 10.7270/Q29Z93CN
University of Neuchâtel					More data for this Ligand-Target Pair
Delta-aminolevulinic acid dehydratase (Escherichia coli)	BDBM82203 (Substrate analogue, 24) Show SMILES COC(=O)CCC(=O)NCC(=O)CCC(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.43E+5	-21.5	n/a	n/a	n/a	n/a	n/a	8.1	37
University of Neuchâtel					Assay Description The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent).				Chembiochem 2: 343-54 (2001) Article DOI: 10.1002/1439-7633(20010504)2 BindingDB Entry DOI: 10.7270/Q29Z93CN
University of Neuchâtel					More data for this Ligand-Target Pair
Delta-aminolevulinic acid dehydratase (Escherichia coli)	BDBM82200 (Substrate analogue, 19) Show SMILES COC(=O)CCN(=O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Patents	Article PubMed	1.88E+6	-16.2	n/a	n/a	n/a	n/a	n/a	8.1	37
University of Neuchâtel					Assay Description The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent).				Chembiochem 2: 343-54 (2001) Article DOI: 10.1002/1439-7633(20010504)2 BindingDB Entry DOI: 10.7270/Q29Z93CN
University of Neuchâtel					More data for this Ligand-Target Pair
Delta-aminolevulinic acid dehydratase (Escherichia coli)	BDBM82191 (Substrate analogue, 8) Show SMILES CC(=O)CCC(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	2.20E+6	-15.8	n/a	n/a	n/a	n/a	n/a	8.1	37
University of Neuchâtel					Assay Description The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent).				Chembiochem 2: 343-54 (2001) Article DOI: 10.1002/1439-7633(20010504)2 BindingDB Entry DOI: 10.7270/Q29Z93CN
University of Neuchâtel					More data for this Ligand-Target Pair
Delta-aminolevulinic acid dehydratase (Escherichia coli)	BDBM82206 (Substrate analogue, 31) Show SMILES OC(=O)CCC(=O)CCCCCN(=O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	4.90E+6	-13.7	n/a	n/a	n/a	n/a	n/a	8.1	37
University of Neuchâtel					Assay Description The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent).				Chembiochem 2: 343-54 (2001) Article DOI: 10.1002/1439-7633(20010504)2 BindingDB Entry DOI: 10.7270/Q29Z93CN
University of Neuchâtel					More data for this Ligand-Target Pair
Delta-aminolevulinic acid dehydratase (Escherichia coli)	BDBM26121 (SUCCINIC ACID \| Substrate analogue, 11 \| Succinate...) Show SMILES OC(=O)CCC(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.25E+7	-11.3	n/a	n/a	n/a	n/a	n/a	8.1	37
University of Neuchâtel					Assay Description The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent).				Chembiochem 2: 343-54 (2001) Article DOI: 10.1002/1439-7633(20010504)2 BindingDB Entry DOI: 10.7270/Q29Z93CN
University of Neuchâtel					More data for this Ligand-Target Pair
Delta-aminolevulinic acid dehydratase (Escherichia coli)	BDBM82208 (Substrate analogue, 33) Show SMILES OC(=O)CCCCNC(=O)CCN(=O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	1.82E+7	-10.3	n/a	n/a	n/a	n/a	n/a	8.1	37
University of Neuchâtel					Assay Description The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent).				Chembiochem 2: 343-54 (2001) Article DOI: 10.1002/1439-7633(20010504)2 BindingDB Entry DOI: 10.7270/Q29Z93CN
University of Neuchâtel					More data for this Ligand-Target Pair
Delta-aminolevulinic acid dehydratase (Escherichia coli)	BDBM82196 (Substrate analogue, 14) Show SMILES NCC(=O)OCC(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	1.82E+7	-10.3	n/a	n/a	n/a	n/a	n/a	8.1	37
University of Neuchâtel					Assay Description The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent).				Chembiochem 2: 343-54 (2001) Article DOI: 10.1002/1439-7633(20010504)2 BindingDB Entry DOI: 10.7270/Q29Z93CN
University of Neuchâtel					More data for this Ligand-Target Pair
Delta-aminolevulinic acid dehydratase (Escherichia coli)	BDBM82197 (Substrate analogue, 15) Show SMILES CC(=O)NCC(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.88E+7	-10.2	n/a	n/a	n/a	n/a	n/a	8.1	37
University of Neuchâtel					Assay Description The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent).				Chembiochem 2: 343-54 (2001) Article DOI: 10.1002/1439-7633(20010504)2 BindingDB Entry DOI: 10.7270/Q29Z93CN
University of Neuchâtel					More data for this Ligand-Target Pair
Delta-aminolevulinic acid dehydratase (Escherichia coli)	BDBM82207 (Substrate analogue, 32) Show SMILES OC(=O)CCCCNC(=O)CCC(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.29E+7	-9.74	n/a	n/a	n/a	n/a	n/a	8.1	37
University of Neuchâtel					Assay Description The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent).				Chembiochem 2: 343-54 (2001) Article DOI: 10.1002/1439-7633(20010504)2 BindingDB Entry DOI: 10.7270/Q29Z93CN
University of Neuchâtel					More data for this Ligand-Target Pair
Delta-aminolevulinic acid dehydratase (Escherichia coli)	BDBM82195 (Substrate analogue, 13) Show SMILES CC(=O)OCC(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents	Article PubMed	2.45E+7	-9.56	n/a	n/a	n/a	n/a	n/a	8.1	37
University of Neuchâtel					Assay Description The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent).				Chembiochem 2: 343-54 (2001) Article DOI: 10.1002/1439-7633(20010504)2 BindingDB Entry DOI: 10.7270/Q29Z93CN
University of Neuchâtel					More data for this Ligand-Target Pair
Delta-aminolevulinic acid dehydratase (Escherichia coli)	BDBM82194 (Substrate analogue, 12) Show SMILES CNC(=O)CCC(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents	Article PubMed	3.64E+7	-8.54	n/a	n/a	n/a	n/a	n/a	8.1	37
University of Neuchâtel					Assay Description The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent).				Chembiochem 2: 343-54 (2001) Article DOI: 10.1002/1439-7633(20010504)2 BindingDB Entry DOI: 10.7270/Q29Z93CN
University of Neuchâtel					More data for this Ligand-Target Pair
Delta-aminolevulinic acid dehydratase (Escherichia coli)	BDBM82193 (Substrate analogue, 10) Show SMILES COC(=O)CCC(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents	Article PubMed	3.84E+7	-8.41	n/a	n/a	n/a	n/a	n/a	8.1	37
University of Neuchâtel					Assay Description The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent).				Chembiochem 2: 343-54 (2001) Article DOI: 10.1002/1439-7633(20010504)2 BindingDB Entry DOI: 10.7270/Q29Z93CN
University of Neuchâtel					More data for this Ligand-Target Pair
Delta-aminolevulinic acid dehydratase (Escherichia coli)	BDBM82201 (Substrate analogue, 20) Show SMILES OC(=O)CCN(=O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase KEGG MMDB PC cid PC sid UniChem Patents	Article PubMed	4.49E+7	-8.00	n/a	n/a	n/a	n/a	n/a	8.1	37
University of Neuchâtel					Assay Description The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent).				Chembiochem 2: 343-54 (2001) Article DOI: 10.1002/1439-7633(20010504)2 BindingDB Entry DOI: 10.7270/Q29Z93CN
University of Neuchâtel					More data for this Ligand-Target Pair
Delta-aminolevulinic acid dehydratase (Escherichia coli)	BDBM50137044 (Substrate analogue, 16 \| [(ammonioacetyl)amino]ace...) Show SMILES [NH3+]CC(=O)NCC([O-])=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	>1.50E+8	>-4.89	n/a	n/a	n/a	n/a	n/a	8.1	37
University of Neuchâtel					Assay Description The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent).				Chembiochem 2: 343-54 (2001) Article DOI: 10.1002/1439-7633(20010504)2 BindingDB Entry DOI: 10.7270/Q29Z93CN
University of Neuchâtel					More data for this Ligand-Target Pair
Delta-aminolevulinic acid dehydratase (Escherichia coli)	BDBM82202 (Substrate analogue, 22) Show SMILES CNC(=O)CCN(=O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents	Article PubMed	2.23E+8	-3.87	n/a	n/a	n/a	n/a	n/a	8.1	37
University of Neuchâtel					Assay Description The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent).				Chembiochem 2: 343-54 (2001) Article DOI: 10.1002/1439-7633(20010504)2 BindingDB Entry DOI: 10.7270/Q29Z93CN
University of Neuchâtel					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50433404 (CHEMBL2380641) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi R&D Curated by ChEMBL					Assay Description Inhibition of mouse recombinant 11beta-HSD1 by scintillation proximity assay				Bioorg Med Chem Lett 23: 2414-21 (2013) Article DOI: 10.1016/j.bmcl.2013.02.018 BindingDB Entry DOI: 10.7270/Q2NV9KMN
Sanofi R&D Curated by ChEMBL					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50433406 (CHEMBL2380643) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi R&D Curated by ChEMBL					Assay Description Inhibition of mouse recombinant 11beta-HSD1 by scintillation proximity assay				Bioorg Med Chem Lett 23: 2414-21 (2013) Article DOI: 10.1016/j.bmcl.2013.02.018 BindingDB Entry DOI: 10.7270/Q2NV9KMN
Sanofi R&D Curated by ChEMBL					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50433405 (CHEMBL2380642) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi R&D Curated by ChEMBL					Assay Description Inhibition of mouse recombinant 11beta-HSD1 by scintillation proximity assay				Bioorg Med Chem Lett 23: 2414-21 (2013) Article DOI: 10.1016/j.bmcl.2013.02.018 BindingDB Entry DOI: 10.7270/Q2NV9KMN
Sanofi R&D Curated by ChEMBL					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50438080 (CHEMBL2409607) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1				Bioorg Med Chem Lett 23: 4685-91 (2013) Article DOI: 10.1016/j.bmcl.2013.05.102 BindingDB Entry DOI: 10.7270/Q2BV7J2H
Sanofi Deutschland GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50438083 (CHEMBL2409755) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1				Bioorg Med Chem Lett 23: 4685-91 (2013) Article DOI: 10.1016/j.bmcl.2013.05.102 BindingDB Entry DOI: 10.7270/Q2BV7J2H
Sanofi Deutschland GmbH Curated by ChEMBL					More data for this Ligand-Target Pair

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