Found 40 hits with Last Name = 'suphakun' and Initial = 'p' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
cGMP-specific 3',5'-cyclic phosphodiesterase
(Rattus norvegicus) | BDBM14390
(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)Show SMILES CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(C)CC1 Show InChI InChI=1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| MMDB PDB Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting method |
Bioorg Med Chem Lett 29: 267-270 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.043 BindingDB Entry DOI: 10.7270/Q2RJ4NT3 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human)) | BDBM50518237
(CHEMBL4552529)Show SMILES [Na;v0+].[#8-]-[#6](=O)-[#6]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-c1ncc2c(-[#7]-[#6]-c3ccc4-[#8]-[#6]-[#8]-c4c3)c(Cl)ccc2n1 Show InChI InChI=1S/C22H21ClN4O4/c23-16-2-3-17-15(11-25-22(26-17)27-7-5-14(6-8-27)21(28)29)20(16)24-10-13-1-4-18-19(9-13)31-12-30-18/h1-4,9,11,14,24H,5-8,10,12H2,(H,28,29)/p-1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of PDE5 (unknown origin) |
Bioorg Med Chem Lett 29: 267-270 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.043 BindingDB Entry DOI: 10.7270/Q2RJ4NT3 |
More data for this Ligand-Target Pair | |
Aurora kinase A
(Homo sapiens (Human)) | BDBM50334594
(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)p...)Show SMILES CNC(=O)c1ccccc1Nc1nc(Nc2ccc(cc2OC)N2CCOCC2)ncc1Cl Show InChI InChI=1S/C23H25ClN6O3/c1-25-22(31)16-5-3-4-6-18(16)27-21-17(24)14-26-23(29-21)28-19-8-7-15(13-20(19)32-2)30-9-11-33-12-10-30/h3-8,13-14H,9-12H2,1-2H3,(H,25,31)(H2,26,27,28,29) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of human AURKA |
Eur J Med Chem 124: 896-905 (2016)
Article DOI: 10.1016/j.ejmech.2016.08.055 BindingDB Entry DOI: 10.7270/Q2DF6T6Q |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM192755
(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)Show SMILES CN1CCN(CC1)c1ccc(Nc2ncc(C)c(Nc3cccc(c3)S(=O)(=O)NC(C)(C)C)n2)cc1 Show InChI InChI=1S/C26H35N7O2S/c1-19-18-27-25(29-20-9-11-22(12-10-20)33-15-13-32(5)14-16-33)30-24(19)28-21-7-6-8-23(17-21)36(34,35)31-26(2,3)4/h6-12,17-18,31H,13-16H2,1-5H3,(H2,27,28,29,30) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of human JAK2 |
Eur J Med Chem 124: 896-905 (2016)
Article DOI: 10.1016/j.ejmech.2016.08.055 BindingDB Entry DOI: 10.7270/Q2DF6T6Q |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM50208589
(CHEMBL3884848)Show SMILES CN1CCN(CC1)c1ccc(Nc2nccc(Nc3cccc(C)c3)n2)cc1C Show InChI InChI=1S/C23H28N6/c1-17-5-4-6-19(15-17)25-22-9-10-24-23(27-22)26-20-7-8-21(18(2)16-20)29-13-11-28(3)12-14-29/h4-10,15-16H,11-14H2,1-3H3,(H2,24,25,26,27) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of human JAK2 using poly (Glu:Tyr) as substrate |
Eur J Med Chem 124: 896-905 (2016)
Article DOI: 10.1016/j.ejmech.2016.08.055 BindingDB Entry DOI: 10.7270/Q2DF6T6Q |
More data for this Ligand-Target Pair | |
cGMP-specific 3',5'-cyclic phosphodiesterase
(Rattus norvegicus) | BDBM50518228
(CHEMBL4445920)Show SMILES NS(=O)(=O)c1cccc(Nc2nc(NCc3ccccc3)c3ccccc3n2)c1 Show InChI InChI=1S/C21H19N5O2S/c22-29(27,28)17-10-6-9-16(13-17)24-21-25-19-12-5-4-11-18(19)20(26-21)23-14-15-7-2-1-3-8-15/h1-13H,14H2,(H2,22,27,28)(H2,23,24,25,26) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 72 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting method |
Bioorg Med Chem Lett 29: 267-270 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.043 BindingDB Entry DOI: 10.7270/Q2RJ4NT3 |
More data for this Ligand-Target Pair | |
cGMP-specific 3',5'-cyclic phosphodiesterase
(Rattus norvegicus) | BDBM50518224
(CHEMBL4570769)Show SMILES NS(=O)(=O)c1cccc(Nc2nc(NCc3cccs3)c3ccccc3n2)c1 Show InChI InChI=1S/C19H17N5O2S2/c20-28(25,26)15-7-3-5-13(11-15)22-19-23-17-9-2-1-8-16(17)18(24-19)21-12-14-6-4-10-27-14/h1-11H,12H2,(H2,20,25,26)(H2,21,22,23,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 89 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting method |
Bioorg Med Chem Lett 29: 267-270 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.043 BindingDB Entry DOI: 10.7270/Q2RJ4NT3 |
More data for this Ligand-Target Pair | |
cGMP-specific 3',5'-cyclic phosphodiesterase
(Rattus norvegicus) | BDBM50518223
(CHEMBL4529354)Show SMILES NS(=O)(=O)c1cccc(Nc2nc(NCc3ccco3)c3ccccc3n2)c1 Show InChI InChI=1S/C19H17N5O3S/c20-28(25,26)15-7-3-5-13(11-15)22-19-23-17-9-2-1-8-16(17)18(24-19)21-12-14-6-4-10-27-14/h1-11H,12H2,(H2,20,25,26)(H2,21,22,23,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 116 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting method |
Bioorg Med Chem Lett 29: 267-270 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.043 BindingDB Entry DOI: 10.7270/Q2RJ4NT3 |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM50208590
(CHEMBL3884104)Show SMILES CN1CCN(CC1)c1ccc(Nc2nccc(Nc3cccc(c3)S(N)(=O)=O)n2)cc1C Show InChI InChI=1S/C22H27N7O2S/c1-16-14-18(6-7-20(16)29-12-10-28(2)11-13-29)26-22-24-9-8-21(27-22)25-17-4-3-5-19(15-17)32(23,30)31/h3-9,14-15H,10-13H2,1-2H3,(H2,23,30,31)(H2,24,25,26,27) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 126 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of human JAK2 using poly (Glu:Tyr) as substrate |
Eur J Med Chem 124: 896-905 (2016)
Article DOI: 10.1016/j.ejmech.2016.08.055 BindingDB Entry DOI: 10.7270/Q2DF6T6Q |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM50208588
(CHEMBL3884240)Show SMILES NS(=O)(=O)c1cccc(Nc2ccnc(Nc3ccc(cc3)N3CCOCC3)n2)c1 Show InChI InChI=1S/C20H22N6O3S/c21-30(27,28)18-3-1-2-16(14-18)23-19-8-9-22-20(25-19)24-15-4-6-17(7-5-15)26-10-12-29-13-11-26/h1-9,14H,10-13H2,(H2,21,27,28)(H2,22,23,24,25) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 129 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of human JAK2 using poly (Glu:Tyr) as substrate |
Eur J Med Chem 124: 896-905 (2016)
Article DOI: 10.1016/j.ejmech.2016.08.055 BindingDB Entry DOI: 10.7270/Q2DF6T6Q |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM50208592
(CHEMBL3883652)Show SMILES CN1CCN(CC1)c1ccc(Nc2nccc(Nc3cccc(C)c3)n2)cc1 Show InChI InChI=1S/C22H26N6/c1-17-4-3-5-19(16-17)24-21-10-11-23-22(26-21)25-18-6-8-20(9-7-18)28-14-12-27(2)13-15-28/h3-11,16H,12-15H2,1-2H3,(H2,23,24,25,26) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of human JAK2 using poly (Glu:Tyr) as substrate |
Eur J Med Chem 124: 896-905 (2016)
Article DOI: 10.1016/j.ejmech.2016.08.055 BindingDB Entry DOI: 10.7270/Q2DF6T6Q |
More data for this Ligand-Target Pair | |
cGMP-specific 3',5'-cyclic phosphodiesterase
(Rattus norvegicus) | BDBM50518225
(CHEMBL4434898)Show InChI InChI=1S/C20H17N5OS/c21-18(26)13-7-9-14(10-8-13)23-20-24-17-6-2-1-5-16(17)19(25-20)22-12-15-4-3-11-27-15/h1-11H,12H2,(H2,21,26)(H2,22,23,24,25) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 177 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting method |
Bioorg Med Chem Lett 29: 267-270 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.043 BindingDB Entry DOI: 10.7270/Q2RJ4NT3 |
More data for this Ligand-Target Pair | |
cGMP-specific 3',5'-cyclic phosphodiesterase
(Rattus norvegicus) | BDBM50518217
(CHEMBL4544782)Show SMILES COc1cc2nc(Nc3cccc(c3)S(N)(=O)=O)nc(NCc3ccccc3)c2cc1OC Show InChI InChI=1S/C23H23N5O4S/c1-31-20-12-18-19(13-21(20)32-2)27-23(26-16-9-6-10-17(11-16)33(24,29)30)28-22(18)25-14-15-7-4-3-5-8-15/h3-13H,14H2,1-2H3,(H2,24,29,30)(H2,25,26,27,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 218 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting method |
Bioorg Med Chem Lett 29: 267-270 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.043 BindingDB Entry DOI: 10.7270/Q2RJ4NT3 |
More data for this Ligand-Target Pair | |
cGMP-specific 3',5'-cyclic phosphodiesterase
(Rattus norvegicus) | BDBM50518232
(CHEMBL4460740)Show SMILES NS(=O)(=O)c1ccc(Nc2nc(NCc3cccs3)c3ccccc3n2)cc1 Show InChI InChI=1S/C19H17N5O2S2/c20-28(25,26)15-9-7-13(8-10-15)22-19-23-17-6-2-1-5-16(17)18(24-19)21-12-14-4-3-11-27-14/h1-11H,12H2,(H2,20,25,26)(H2,21,22,23,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 224 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting method |
Bioorg Med Chem Lett 29: 267-270 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.043 BindingDB Entry DOI: 10.7270/Q2RJ4NT3 |
More data for this Ligand-Target Pair | |
cGMP-specific 3',5'-cyclic phosphodiesterase
(Rattus norvegicus) | BDBM50518220
(CHEMBL4540726)Show SMILES COc1cc2nc(Nc3cccc(c3)S(N)(=O)=O)nc(NCc3ccco3)c2cc1OC Show InChI InChI=1S/C21H21N5O5S/c1-29-18-10-16-17(11-19(18)30-2)25-21(26-20(16)23-12-14-6-4-8-31-14)24-13-5-3-7-15(9-13)32(22,27)28/h3-11H,12H2,1-2H3,(H2,22,27,28)(H2,23,24,25,26) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 284 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting method |
Bioorg Med Chem Lett 29: 267-270 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.043 BindingDB Entry DOI: 10.7270/Q2RJ4NT3 |
More data for this Ligand-Target Pair | |
cGMP-specific 3',5'-cyclic phosphodiesterase
(Rattus norvegicus) | BDBM50518234
(CHEMBL4516390)Show InChI InChI=1S/C20H17N5OS/c21-18(26)13-5-3-6-14(11-13)23-20-24-17-9-2-1-8-16(17)19(25-20)22-12-15-7-4-10-27-15/h1-11H,12H2,(H2,21,26)(H2,22,23,24,25) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 290 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting method |
Bioorg Med Chem Lett 29: 267-270 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.043 BindingDB Entry DOI: 10.7270/Q2RJ4NT3 |
More data for this Ligand-Target Pair | |
cGMP-specific 3',5'-cyclic phosphodiesterase
(Rattus norvegicus) | BDBM50518227
(CHEMBL4452377)Show SMILES COc1cccc(CNc2nc(Nc3cccc(c3)S(N)(=O)=O)nc3ccccc23)c1 Show InChI InChI=1S/C22H21N5O3S/c1-30-17-8-4-6-15(12-17)14-24-21-19-10-2-3-11-20(19)26-22(27-21)25-16-7-5-9-18(13-16)31(23,28)29/h2-13H,14H2,1H3,(H2,23,28,29)(H2,24,25,26,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting method |
Bioorg Med Chem Lett 29: 267-270 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.043 BindingDB Entry DOI: 10.7270/Q2RJ4NT3 |
More data for this Ligand-Target Pair | |
cGMP-specific 3',5'-cyclic phosphodiesterase
(Rattus norvegicus) | BDBM50518233
(CHEMBL4526365)Show SMILES COc1cccc(CNc2nc(Nc3cccc(c3)S(N)(=O)=O)nc3cc(OC)c(OC)cc23)c1 Show InChI InChI=1S/C24H25N5O5S/c1-32-17-8-4-6-15(10-17)14-26-23-19-12-21(33-2)22(34-3)13-20(19)28-24(29-23)27-16-7-5-9-18(11-16)35(25,30)31/h4-13H,14H2,1-3H3,(H2,25,30,31)(H2,26,27,28,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 443 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting method |
Bioorg Med Chem Lett 29: 267-270 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.043 BindingDB Entry DOI: 10.7270/Q2RJ4NT3 |
More data for this Ligand-Target Pair | |
cGMP-specific 3',5'-cyclic phosphodiesterase
(Rattus norvegicus) | BDBM50518226
(CHEMBL4534674)Show SMILES C(Nc1nc(Nc2ccc(cc2)N2CCOCC2)nc2ccccc12)c1cccs1 Show InChI InChI=1S/C23H23N5OS/c1-2-6-21-20(5-1)22(24-16-19-4-3-15-30-19)27-23(26-21)25-17-7-9-18(10-8-17)28-11-13-29-14-12-28/h1-10,15H,11-14,16H2,(H2,24,25,26,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 514 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting method |
Bioorg Med Chem Lett 29: 267-270 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.043 BindingDB Entry DOI: 10.7270/Q2RJ4NT3 |
More data for this Ligand-Target Pair | |
cGMP-specific 3',5'-cyclic phosphodiesterase
(Rattus norvegicus) | BDBM50518230
(CHEMBL4453311)Show SMILES C(Nc1nc(Nc2ccc(cc2)N2CCOCC2)nc2ccccc12)c1ccccc1 Show InChI InChI=1S/C25H25N5O/c1-2-6-19(7-3-1)18-26-24-22-8-4-5-9-23(22)28-25(29-24)27-20-10-12-21(13-11-20)30-14-16-31-17-15-30/h1-13H,14-18H2,(H2,26,27,28,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 525 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting method |
Bioorg Med Chem Lett 29: 267-270 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.043 BindingDB Entry DOI: 10.7270/Q2RJ4NT3 |
More data for this Ligand-Target Pair | |
cGMP-specific 3',5'-cyclic phosphodiesterase
(Rattus norvegicus) | BDBM50518221
(CHEMBL4450878)Show SMILES COc1cc2nc(Nc3cccc(c3)S(N)(=O)=O)nc(NCc3cccs3)c2cc1OC Show InChI InChI=1S/C21H21N5O4S2/c1-29-18-10-16-17(11-19(18)30-2)25-21(26-20(16)23-12-14-6-4-8-31-14)24-13-5-3-7-15(9-13)32(22,27)28/h3-11H,12H2,1-2H3,(H2,22,27,28)(H2,23,24,25,26) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 555 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting method |
Bioorg Med Chem Lett 29: 267-270 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.043 BindingDB Entry DOI: 10.7270/Q2RJ4NT3 |
More data for this Ligand-Target Pair | |
cGMP-specific 3',5'-cyclic phosphodiesterase
(Rattus norvegicus) | BDBM50518218
(CHEMBL4567109)Show SMILES O=C(Nc1ccccc1)Nc1ccc(Nc2nc(NCc3cccs3)c3ccccc3n2)cc1 Show InChI InChI=1S/C26H22N6OS/c33-26(29-18-7-2-1-3-8-18)30-20-14-12-19(13-15-20)28-25-31-23-11-5-4-10-22(23)24(32-25)27-17-21-9-6-16-34-21/h1-16H,17H2,(H2,29,30,33)(H2,27,28,31,32) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 775 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting method |
Bioorg Med Chem Lett 29: 267-270 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.043 BindingDB Entry DOI: 10.7270/Q2RJ4NT3 |
More data for this Ligand-Target Pair | |
cGMP-specific 3',5'-cyclic phosphodiesterase
(Rattus norvegicus) | BDBM50518229
(CHEMBL4558761)Show SMILES NS(=O)(=O)c1ccc(Nc2nc(NCc3ccccc3)c3ccccc3n2)cc1 Show InChI InChI=1S/C21H19N5O2S/c22-29(27,28)17-12-10-16(11-13-17)24-21-25-19-9-5-4-8-18(19)20(26-21)23-14-15-6-2-1-3-7-15/h1-13H,14H2,(H2,22,27,28)(H2,23,24,25,26) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 946 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting method |
Bioorg Med Chem Lett 29: 267-270 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.043 BindingDB Entry DOI: 10.7270/Q2RJ4NT3 |
More data for this Ligand-Target Pair | |
cGMP-specific 3',5'-cyclic phosphodiesterase
(Rattus norvegicus) | BDBM50518236
(CHEMBL4469064)Show SMILES CN(C)S(=O)(=O)c1ccc(Nc2nc(NCc3ccccc3)c3ccccc3n2)cc1 Show InChI InChI=1S/C23H23N5O2S/c1-28(2)31(29,30)19-14-12-18(13-15-19)25-23-26-21-11-7-6-10-20(21)22(27-23)24-16-17-8-4-3-5-9-17/h3-15H,16H2,1-2H3,(H2,24,25,26,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting method |
Bioorg Med Chem Lett 29: 267-270 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.043 BindingDB Entry DOI: 10.7270/Q2RJ4NT3 |
More data for this Ligand-Target Pair | |
cGMP-specific 3',5'-cyclic phosphodiesterase
(Rattus norvegicus) | BDBM50518231
(CHEMBL597248 | GNF-Pf-4180 | MMV006169)Show InChI InChI=1S/C21H18N4/c1-3-9-16(10-4-1)15-22-20-18-13-7-8-14-19(18)24-21(25-20)23-17-11-5-2-6-12-17/h1-14H,15H2,(H2,22,23,24,25) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.38E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting method |
Bioorg Med Chem Lett 29: 267-270 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.043 BindingDB Entry DOI: 10.7270/Q2RJ4NT3 |
More data for this Ligand-Target Pair | |
cGMP-specific 3',5'-cyclic phosphodiesterase
(Rattus norvegicus) | BDBM50518235
(CHEMBL4525521)Show InChI InChI=1S/C19H16N4S/c1-2-7-14(8-3-1)21-19-22-17-11-5-4-10-16(17)18(23-19)20-13-15-9-6-12-24-15/h1-12H,13H2,(H2,20,21,22,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting method |
Bioorg Med Chem Lett 29: 267-270 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.043 BindingDB Entry DOI: 10.7270/Q2RJ4NT3 |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM50208589
(CHEMBL3884848)Show SMILES CN1CCN(CC1)c1ccc(Nc2nccc(Nc3cccc(C)c3)n2)cc1C Show InChI InChI=1S/C23H28N6/c1-17-5-4-6-19(15-17)25-22-9-10-24-23(27-22)26-20-7-8-21(18(2)16-20)29-13-11-28(3)12-14-29/h4-10,15-16H,11-14H2,1-3H3,(H2,24,25,26,27) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of human JAK3 using poly (Glu:Tyr) as substrate |
Eur J Med Chem 124: 896-905 (2016)
Article DOI: 10.1016/j.ejmech.2016.08.055 BindingDB Entry DOI: 10.7270/Q2DF6T6Q |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM50208592
(CHEMBL3883652)Show SMILES CN1CCN(CC1)c1ccc(Nc2nccc(Nc3cccc(C)c3)n2)cc1 Show InChI InChI=1S/C22H26N6/c1-17-4-3-5-19(16-17)24-21-10-11-23-22(26-21)25-18-6-8-20(9-7-18)28-14-12-27(2)13-15-28/h3-11,16H,12-15H2,1-2H3,(H2,23,24,25,26) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of human JAK3 using poly (Glu:Tyr) as substrate |
Eur J Med Chem 124: 896-905 (2016)
Article DOI: 10.1016/j.ejmech.2016.08.055 BindingDB Entry DOI: 10.7270/Q2DF6T6Q |
More data for this Ligand-Target Pair | |
cGMP-specific 3',5'-cyclic phosphodiesterase
(Rattus norvegicus) | BDBM50518222
(CHEMBL4552918)Show SMILES Cc1cc(Nc2nc(Nc3cccc(c3)S(N)(=O)=O)nc3ccccc23)n[nH]1 Show InChI InChI=1S/C18H17N7O2S/c1-11-9-16(25-24-11)22-17-14-7-2-3-8-15(14)21-18(23-17)20-12-5-4-6-13(10-12)28(19,26)27/h2-10H,1H3,(H2,19,26,27)(H3,20,21,22,23,24,25) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.71E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting method |
Bioorg Med Chem Lett 29: 267-270 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.043 BindingDB Entry DOI: 10.7270/Q2RJ4NT3 |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM50208590
(CHEMBL3884104)Show SMILES CN1CCN(CC1)c1ccc(Nc2nccc(Nc3cccc(c3)S(N)(=O)=O)n2)cc1C Show InChI InChI=1S/C22H27N7O2S/c1-16-14-18(6-7-20(16)29-12-10-28(2)11-13-29)26-22-24-9-8-21(27-22)25-17-4-3-5-19(15-17)32(23,30)31/h3-9,14-15H,10-13H2,1-2H3,(H2,23,30,31)(H2,24,25,26,27) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of human JAK3 using poly (Glu:Tyr) as substrate |
Eur J Med Chem 124: 896-905 (2016)
Article DOI: 10.1016/j.ejmech.2016.08.055 BindingDB Entry DOI: 10.7270/Q2DF6T6Q |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM50208588
(CHEMBL3884240)Show SMILES NS(=O)(=O)c1cccc(Nc2ccnc(Nc3ccc(cc3)N3CCOCC3)n2)c1 Show InChI InChI=1S/C20H22N6O3S/c21-30(27,28)18-3-1-2-16(14-18)23-19-8-9-22-20(25-19)24-15-4-6-17(7-5-15)26-10-12-29-13-11-26/h1-9,14H,10-13H2,(H2,21,27,28)(H2,22,23,24,25) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of human JAK3 using poly (Glu:Tyr) as substrate |
Eur J Med Chem 124: 896-905 (2016)
Article DOI: 10.1016/j.ejmech.2016.08.055 BindingDB Entry DOI: 10.7270/Q2DF6T6Q |
More data for this Ligand-Target Pair | |
cGMP-specific 3',5'-cyclic phosphodiesterase
(Rattus norvegicus) | BDBM50518219
(CHEMBL4565213)Show InChI InChI=1S/C17H15ClN4/c18-15-12-20-17(21-14-9-5-2-6-10-14)22-16(15)19-11-13-7-3-1-4-8-13/h1-10,12H,11H2,(H2,19,20,21,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting method |
Bioorg Med Chem Lett 29: 267-270 (2019)
Article DOI: 10.1016/j.bmcl.2018.11.043 BindingDB Entry DOI: 10.7270/Q2RJ4NT3 |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50208592
(CHEMBL3883652)Show SMILES CN1CCN(CC1)c1ccc(Nc2nccc(Nc3cccc(C)c3)n2)cc1 Show InChI InChI=1S/C22H26N6/c1-17-4-3-5-19(16-17)24-21-10-11-23-22(26-21)25-18-6-8-20(9-7-18)28-14-12-27(2)13-15-28/h3-11,16H,12-15H2,1-2H3,(H2,23,24,25,26) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of human EGFR using poly (Glu:Tyr) as substrate measured for 1.5 hrs by oregon green 488 dye-based fluorescence assay |
Eur J Med Chem 124: 896-905 (2016)
Article DOI: 10.1016/j.ejmech.2016.08.055 BindingDB Entry DOI: 10.7270/Q2DF6T6Q |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5
(Homo sapiens (Human)) | BDBM50262022
(CHEMBL4098016)Show InChI InChI=1S/C17H16N4O/c1-22-15-7-5-12(6-8-15)16-9-10-19-17(21-16)20-14-4-2-3-13(18)11-14/h2-11H,18H2,1H3,(H,19,20,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Chemistry, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand.
Curated by ChEMBL
| Assay Description Inhibition of human CDK5 |
Bioorg Med Chem Lett 27: 4749-4754 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.063 BindingDB Entry DOI: 10.7270/Q2D2213J |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM50208591
(CHEMBL3885292)Show SMILES CN1CCN(CC1)c1ccc(Nc2ncc(C#N)c(Nc3cccc(c3)S(=O)(=O)NC(C)(C)C)n2)cc1C Show InChI InChI=1S/C27H34N8O2S/c1-19-15-22(9-10-24(19)35-13-11-34(5)12-14-35)31-26-29-18-20(17-28)25(32-26)30-21-7-6-8-23(16-21)38(36,37)33-27(2,3)4/h6-10,15-16,18,33H,11-14H2,1-5H3,(H2,29,30,31,32) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of human JAK3 using poly (Glu:Tyr) as substrate |
Eur J Med Chem 124: 896-905 (2016)
Article DOI: 10.1016/j.ejmech.2016.08.055 BindingDB Entry DOI: 10.7270/Q2DF6T6Q |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM50208591
(CHEMBL3885292)Show SMILES CN1CCN(CC1)c1ccc(Nc2ncc(C#N)c(Nc3cccc(c3)S(=O)(=O)NC(C)(C)C)n2)cc1C Show InChI InChI=1S/C27H34N8O2S/c1-19-15-22(9-10-24(19)35-13-11-34(5)12-14-35)31-26-29-18-20(17-28)25(32-26)30-21-7-6-8-23(16-21)38(36,37)33-27(2,3)4/h6-10,15-16,18,33H,11-14H2,1-5H3,(H2,29,30,31,32) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of human JAK2 using poly (Glu:Tyr) as substrate |
Eur J Med Chem 124: 896-905 (2016)
Article DOI: 10.1016/j.ejmech.2016.08.055 BindingDB Entry DOI: 10.7270/Q2DF6T6Q |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50208588
(CHEMBL3884240)Show SMILES NS(=O)(=O)c1cccc(Nc2ccnc(Nc3ccc(cc3)N3CCOCC3)n2)c1 Show InChI InChI=1S/C20H22N6O3S/c21-30(27,28)18-3-1-2-16(14-18)23-19-8-9-22-20(25-19)24-15-4-6-17(7-5-15)26-10-12-29-13-11-26/h1-9,14H,10-13H2,(H2,21,27,28)(H2,22,23,24,25) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of human EGFR using poly (Glu:Tyr) as substrate measured for 1.5 hrs by oregon green 488 dye-based fluorescence assay |
Eur J Med Chem 124: 896-905 (2016)
Article DOI: 10.1016/j.ejmech.2016.08.055 BindingDB Entry DOI: 10.7270/Q2DF6T6Q |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50208591
(CHEMBL3885292)Show SMILES CN1CCN(CC1)c1ccc(Nc2ncc(C#N)c(Nc3cccc(c3)S(=O)(=O)NC(C)(C)C)n2)cc1C Show InChI InChI=1S/C27H34N8O2S/c1-19-15-22(9-10-24(19)35-13-11-34(5)12-14-35)31-26-29-18-20(17-28)25(32-26)30-21-7-6-8-23(16-21)38(36,37)33-27(2,3)4/h6-10,15-16,18,33H,11-14H2,1-5H3,(H2,29,30,31,32) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of human EGFR using poly (Glu:Tyr) as substrate measured for 1.5 hrs by oregon green 488 dye-based fluorescence assay |
Eur J Med Chem 124: 896-905 (2016)
Article DOI: 10.1016/j.ejmech.2016.08.055 BindingDB Entry DOI: 10.7270/Q2DF6T6Q |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50208590
(CHEMBL3884104)Show SMILES CN1CCN(CC1)c1ccc(Nc2nccc(Nc3cccc(c3)S(N)(=O)=O)n2)cc1C Show InChI InChI=1S/C22H27N7O2S/c1-16-14-18(6-7-20(16)29-12-10-28(2)11-13-29)26-22-24-9-8-21(27-22)25-17-4-3-5-19(15-17)32(23,30)31/h3-9,14-15H,10-13H2,1-2H3,(H2,23,30,31)(H2,24,25,26,27) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of human EGFR using poly (Glu:Tyr) as substrate measured for 1.5 hrs by oregon green 488 dye-based fluorescence assay |
Eur J Med Chem 124: 896-905 (2016)
Article DOI: 10.1016/j.ejmech.2016.08.055 BindingDB Entry DOI: 10.7270/Q2DF6T6Q |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50208589
(CHEMBL3884848)Show SMILES CN1CCN(CC1)c1ccc(Nc2nccc(Nc3cccc(C)c3)n2)cc1C Show InChI InChI=1S/C23H28N6/c1-17-5-4-6-19(15-17)25-22-9-10-24-23(27-22)26-20-7-8-21(18(2)16-20)29-13-11-28(3)12-14-29/h4-10,15-16H,11-14H2,1-3H3,(H2,24,25,26,27) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kasetsart University
Curated by ChEMBL
| Assay Description Inhibition of human EGFR using poly (Glu:Tyr) as substrate measured for 1.5 hrs by oregon green 488 dye-based fluorescence assay |
Eur J Med Chem 124: 896-905 (2016)
Article DOI: 10.1016/j.ejmech.2016.08.055 BindingDB Entry DOI: 10.7270/Q2DF6T6Q |
More data for this Ligand-Target Pair | |