Compile Data Set for Download or QSAR

Found 23 hits with Last Name = 'bhagwat' and Initial = 'sv'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50339059 (3-cyclobutyl-1-(2-phenylquinolin-7-yl)-imidazo[1,5...) Show SMILES Nc1nccn2c(nc(-c3ccc4ccc(nc4c3)-c3ccccc3)c12)C1CCC1 Show InChI InChI=1S/C25H21N5/c26-24-23-22(29-25(18-7-4-8-18)30(23)14-13-27-24)19-10-9-17-11-12-20(28-21(17)15-19)16-5-2-1-3-6-16/h1-3,5-6,9-15,18H,4,7-8H2,(H2,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of IGF-1R by ELISA				Bioorg Med Chem Lett 21: 2092-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.139 BindingDB Entry DOI: 10.7270/Q23N23QH
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50340954 (CHEMBL1762110 | Trans-N-((-4-(8-amino-1-(1H-indol-...) Show SMILES CC(=O)NC[C@H]1CC[C@@H](CC1)c1nc(-c2cc3ccccc3[nH]2)c2c(N)nccn12 |r,wU:8.11,wD:5.4,(30.4,-52.78,;31.44,-51.63,;32.94,-51.96,;30.97,-50.17,;32,-49.03,;31.53,-47.56,;32.56,-46.41,;32.09,-44.94,;30.58,-44.63,;29.54,-45.77,;30.01,-47.24,;30.1,-43.16,;31.01,-41.9,;30.1,-40.65,;30.58,-39.19,;29.67,-37.94,;30.58,-36.7,;30.27,-35.2,;31.41,-34.17,;32.87,-34.65,;33.19,-36.15,;32.04,-37.18,;32.04,-38.72,;28.62,-41.13,;27.29,-40.37,;27.29,-38.83,;25.96,-41.14,;25.96,-42.68,;27.29,-43.45,;28.63,-42.68,)| Show InChI InChI=1S/C23H26N6O/c1-14(30)26-13-15-6-8-16(9-7-15)23-28-20(21-22(24)25-10-11-29(21)23)19-12-17-4-2-3-5-18(17)27-19/h2-5,10-12,15-16,27H,6-9,13H2,1H3,(H2,24,25)(H,26,30)/t15-,16-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of cRaf				Bioorg Med Chem Lett 21: 2092-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.139 BindingDB Entry DOI: 10.7270/Q23N23QH
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50199683 (3-(8-amino-3-cyclobutylimidazo[1,5-a]pyrazin-1-yl)...) Show SMILES Nc1nccn2c(nc(-c3cccc(O)c3)c12)C1CCC1 Show InChI InChI=1S/C16H16N4O/c17-15-14-13(11-5-2-6-12(21)9-11)19-16(10-3-1-4-10)20(14)8-7-18-15/h2,5-10,21H,1,3-4H2,(H2,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of IGF-1R by ELISA				Bioorg Med Chem Lett 21: 2092-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.139 BindingDB Entry DOI: 10.7270/Q23N23QH
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50340952 (4-(8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-...) Show SMILES CN(C)C(=O)N1CCC(CC1)c1nc(-c2cc3ccccc3[nH]2)c2c(N)nccn12 Show InChI InChI=1S/C22H25N7O/c1-27(2)22(30)28-10-7-14(8-11-28)21-26-18(19-20(23)24-9-12-29(19)21)17-13-15-5-3-4-6-16(15)25-17/h3-6,9,12-14,25H,7-8,10-11H2,1-2H3,(H2,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of Src				Bioorg Med Chem Lett 21: 2092-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.139 BindingDB Entry DOI: 10.7270/Q23N23QH
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1 (Homo sapiens (Human))	BDBM50340954 (CHEMBL1762110 | Trans-N-((-4-(8-amino-1-(1H-indol-...) Show SMILES CC(=O)NC[C@H]1CC[C@@H](CC1)c1nc(-c2cc3ccccc3[nH]2)c2c(N)nccn12 |r,wU:8.11,wD:5.4,(30.4,-52.78,;31.44,-51.63,;32.94,-51.96,;30.97,-50.17,;32,-49.03,;31.53,-47.56,;32.56,-46.41,;32.09,-44.94,;30.58,-44.63,;29.54,-45.77,;30.01,-47.24,;30.1,-43.16,;31.01,-41.9,;30.1,-40.65,;30.58,-39.19,;29.67,-37.94,;30.58,-36.7,;30.27,-35.2,;31.41,-34.17,;32.87,-34.65,;33.19,-36.15,;32.04,-37.18,;32.04,-38.72,;28.62,-41.13,;27.29,-40.37,;27.29,-38.83,;25.96,-41.14,;25.96,-42.68,;27.29,-43.45,;28.63,-42.68,)| Show InChI InChI=1S/C23H26N6O/c1-14(30)26-13-15-6-8-16(9-7-15)23-28-20(21-22(24)25-10-11-29(21)23)19-12-17-4-2-3-5-18(17)27-19/h2-5,10-12,15-16,27H,6-9,13H2,1H3,(H2,24,25)(H,26,30)/t15-,16-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of MEK1				Bioorg Med Chem Lett 21: 2092-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.139 BindingDB Entry DOI: 10.7270/Q23N23QH
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50340952 (4-(8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-...) Show SMILES CN(C)C(=O)N1CCC(CC1)c1nc(-c2cc3ccccc3[nH]2)c2c(N)nccn12 Show InChI InChI=1S/C22H25N7O/c1-27(2)22(30)28-10-7-14(8-11-28)21-26-18(19-20(23)24-9-12-29(19)21)17-13-15-5-3-4-6-16(15)25-17/h3-6,9,12-14,25H,7-8,10-11H2,1-2H3,(H2,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of cRaf				Bioorg Med Chem Lett 21: 2092-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.139 BindingDB Entry DOI: 10.7270/Q23N23QH
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50340954 (CHEMBL1762110 | Trans-N-((-4-(8-amino-1-(1H-indol-...) Show SMILES CC(=O)NC[C@H]1CC[C@@H](CC1)c1nc(-c2cc3ccccc3[nH]2)c2c(N)nccn12 |r,wU:8.11,wD:5.4,(30.4,-52.78,;31.44,-51.63,;32.94,-51.96,;30.97,-50.17,;32,-49.03,;31.53,-47.56,;32.56,-46.41,;32.09,-44.94,;30.58,-44.63,;29.54,-45.77,;30.01,-47.24,;30.1,-43.16,;31.01,-41.9,;30.1,-40.65,;30.58,-39.19,;29.67,-37.94,;30.58,-36.7,;30.27,-35.2,;31.41,-34.17,;32.87,-34.65,;33.19,-36.15,;32.04,-37.18,;32.04,-38.72,;28.62,-41.13,;27.29,-40.37,;27.29,-38.83,;25.96,-41.14,;25.96,-42.68,;27.29,-43.45,;28.63,-42.68,)| Show InChI InChI=1S/C23H26N6O/c1-14(30)26-13-15-6-8-16(9-7-15)23-28-20(21-22(24)25-10-11-29(21)23)19-12-17-4-2-3-5-18(17)27-19/h2-5,10-12,15-16,27H,6-9,13H2,1H3,(H2,24,25)(H,26,30)/t15-,16-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.96E+3	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of Abl				Bioorg Med Chem Lett 21: 2092-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.139 BindingDB Entry DOI: 10.7270/Q23N23QH
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50340954 (CHEMBL1762110 | Trans-N-((-4-(8-amino-1-(1H-indol-...) Show SMILES CC(=O)NC[C@H]1CC[C@@H](CC1)c1nc(-c2cc3ccccc3[nH]2)c2c(N)nccn12 |r,wU:8.11,wD:5.4,(30.4,-52.78,;31.44,-51.63,;32.94,-51.96,;30.97,-50.17,;32,-49.03,;31.53,-47.56,;32.56,-46.41,;32.09,-44.94,;30.58,-44.63,;29.54,-45.77,;30.01,-47.24,;30.1,-43.16,;31.01,-41.9,;30.1,-40.65,;30.58,-39.19,;29.67,-37.94,;30.58,-36.7,;30.27,-35.2,;31.41,-34.17,;32.87,-34.65,;33.19,-36.15,;32.04,-37.18,;32.04,-38.72,;28.62,-41.13,;27.29,-40.37,;27.29,-38.83,;25.96,-41.14,;25.96,-42.68,;27.29,-43.45,;28.63,-42.68,)| Show InChI InChI=1S/C23H26N6O/c1-14(30)26-13-15-6-8-16(9-7-15)23-28-20(21-22(24)25-10-11-29(21)23)19-12-17-4-2-3-5-18(17)27-19/h2-5,10-12,15-16,27H,6-9,13H2,1H3,(H2,24,25)(H,26,30)/t15-,16-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of IGF-1R by ELISA				Bioorg Med Chem Lett 21: 2092-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.139 BindingDB Entry DOI: 10.7270/Q23N23QH
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50340954 (CHEMBL1762110 | Trans-N-((-4-(8-amino-1-(1H-indol-...) Show SMILES CC(=O)NC[C@H]1CC[C@@H](CC1)c1nc(-c2cc3ccccc3[nH]2)c2c(N)nccn12 |r,wU:8.11,wD:5.4,(30.4,-52.78,;31.44,-51.63,;32.94,-51.96,;30.97,-50.17,;32,-49.03,;31.53,-47.56,;32.56,-46.41,;32.09,-44.94,;30.58,-44.63,;29.54,-45.77,;30.01,-47.24,;30.1,-43.16,;31.01,-41.9,;30.1,-40.65,;30.58,-39.19,;29.67,-37.94,;30.58,-36.7,;30.27,-35.2,;31.41,-34.17,;32.87,-34.65,;33.19,-36.15,;32.04,-37.18,;32.04,-38.72,;28.62,-41.13,;27.29,-40.37,;27.29,-38.83,;25.96,-41.14,;25.96,-42.68,;27.29,-43.45,;28.63,-42.68,)| Show InChI InChI=1S/C23H26N6O/c1-14(30)26-13-15-6-8-16(9-7-15)23-28-20(21-22(24)25-10-11-29(21)23)19-12-17-4-2-3-5-18(17)27-19/h2-5,10-12,15-16,27H,6-9,13H2,1H3,(H2,24,25)(H,26,30)/t15-,16-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of EGFR				Bioorg Med Chem Lett 21: 2092-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.139 BindingDB Entry DOI: 10.7270/Q23N23QH
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50340954 (CHEMBL1762110 | Trans-N-((-4-(8-amino-1-(1H-indol-...) Show SMILES CC(=O)NC[C@H]1CC[C@@H](CC1)c1nc(-c2cc3ccccc3[nH]2)c2c(N)nccn12 |r,wU:8.11,wD:5.4,(30.4,-52.78,;31.44,-51.63,;32.94,-51.96,;30.97,-50.17,;32,-49.03,;31.53,-47.56,;32.56,-46.41,;32.09,-44.94,;30.58,-44.63,;29.54,-45.77,;30.01,-47.24,;30.1,-43.16,;31.01,-41.9,;30.1,-40.65,;30.58,-39.19,;29.67,-37.94,;30.58,-36.7,;30.27,-35.2,;31.41,-34.17,;32.87,-34.65,;33.19,-36.15,;32.04,-37.18,;32.04,-38.72,;28.62,-41.13,;27.29,-40.37,;27.29,-38.83,;25.96,-41.14,;25.96,-42.68,;27.29,-43.45,;28.63,-42.68,)| Show InChI InChI=1S/C23H26N6O/c1-14(30)26-13-15-6-8-16(9-7-15)23-28-20(21-22(24)25-10-11-29(21)23)19-12-17-4-2-3-5-18(17)27-19/h2-5,10-12,15-16,27H,6-9,13H2,1H3,(H2,24,25)(H,26,30)/t15-,16-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 21: 2092-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.139 BindingDB Entry DOI: 10.7270/Q23N23QH
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50340954 (CHEMBL1762110 | Trans-N-((-4-(8-amino-1-(1H-indol-...) Show SMILES CC(=O)NC[C@H]1CC[C@@H](CC1)c1nc(-c2cc3ccccc3[nH]2)c2c(N)nccn12 |r,wU:8.11,wD:5.4,(30.4,-52.78,;31.44,-51.63,;32.94,-51.96,;30.97,-50.17,;32,-49.03,;31.53,-47.56,;32.56,-46.41,;32.09,-44.94,;30.58,-44.63,;29.54,-45.77,;30.01,-47.24,;30.1,-43.16,;31.01,-41.9,;30.1,-40.65,;30.58,-39.19,;29.67,-37.94,;30.58,-36.7,;30.27,-35.2,;31.41,-34.17,;32.87,-34.65,;33.19,-36.15,;32.04,-37.18,;32.04,-38.72,;28.62,-41.13,;27.29,-40.37,;27.29,-38.83,;25.96,-41.14,;25.96,-42.68,;27.29,-43.45,;28.63,-42.68,)| Show InChI InChI=1S/C23H26N6O/c1-14(30)26-13-15-6-8-16(9-7-15)23-28-20(21-22(24)25-10-11-29(21)23)19-12-17-4-2-3-5-18(17)27-19/h2-5,10-12,15-16,27H,6-9,13H2,1H3,(H2,24,25)(H,26,30)/t15-,16-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of Src				Bioorg Med Chem Lett 21: 2092-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.139 BindingDB Entry DOI: 10.7270/Q23N23QH
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50340952 (4-(8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-...) Show SMILES CN(C)C(=O)N1CCC(CC1)c1nc(-c2cc3ccccc3[nH]2)c2c(N)nccn12 Show InChI InChI=1S/C22H25N7O/c1-27(2)22(30)28-10-7-14(8-11-28)21-26-18(19-20(23)24-9-12-29(19)21)17-13-15-5-3-4-6-16(15)25-17/h3-6,9,12-14,25H,7-8,10-11H2,1-2H3,(H2,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 21: 2092-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.139 BindingDB Entry DOI: 10.7270/Q23N23QH
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50340953 (3-cyclobutyl-1-(quinolin-7-yl)imidazo[1,5-a]pyrazi...) Show SMILES Nc1nccn2c(nc(-c3ccc4cccnc4c3)c12)C1CCC1 Show InChI InChI=1S/C19H17N5/c20-18-17-16(14-7-6-12-5-2-8-21-15(12)11-14)23-19(13-3-1-4-13)24(17)10-9-22-18/h2,5-11,13H,1,3-4H2,(H2,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of IGF-1R by ELISA				Bioorg Med Chem Lett 21: 2092-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.139 BindingDB Entry DOI: 10.7270/Q23N23QH
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50340952 (4-(8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-...) Show SMILES CN(C)C(=O)N1CCC(CC1)c1nc(-c2cc3ccccc3[nH]2)c2c(N)nccn12 Show InChI InChI=1S/C22H25N7O/c1-27(2)22(30)28-10-7-14(8-11-28)21-26-18(19-20(23)24-9-12-29(19)21)17-13-15-5-3-4-6-16(15)25-17/h3-6,9,12-14,25H,7-8,10-11H2,1-2H3,(H2,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of Abl				Bioorg Med Chem Lett 21: 2092-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.139 BindingDB Entry DOI: 10.7270/Q23N23QH
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1 (Homo sapiens (Human))	BDBM50340952 (4-(8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-...) Show SMILES CN(C)C(=O)N1CCC(CC1)c1nc(-c2cc3ccccc3[nH]2)c2c(N)nccn12 Show InChI InChI=1S/C22H25N7O/c1-27(2)22(30)28-10-7-14(8-11-28)21-26-18(19-20(23)24-9-12-29(19)21)17-13-15-5-3-4-6-16(15)25-17/h3-6,9,12-14,25H,7-8,10-11H2,1-2H3,(H2,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of MEK1				Bioorg Med Chem Lett 21: 2092-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.139 BindingDB Entry DOI: 10.7270/Q23N23QH
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50340952 (4-(8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-...) Show SMILES CN(C)C(=O)N1CCC(CC1)c1nc(-c2cc3ccccc3[nH]2)c2c(N)nccn12 Show InChI InChI=1S/C22H25N7O/c1-27(2)22(30)28-10-7-14(8-11-28)21-26-18(19-20(23)24-9-12-29(19)21)17-13-15-5-3-4-6-16(15)25-17/h3-6,9,12-14,25H,7-8,10-11H2,1-2H3,(H2,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of EGFR				Bioorg Med Chem Lett 21: 2092-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.139 BindingDB Entry DOI: 10.7270/Q23N23QH
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50340954 (CHEMBL1762110 | Trans-N-((-4-(8-amino-1-(1H-indol-...) Show SMILES CC(=O)NC[C@H]1CC[C@@H](CC1)c1nc(-c2cc3ccccc3[nH]2)c2c(N)nccn12 |r,wU:8.11,wD:5.4,(30.4,-52.78,;31.44,-51.63,;32.94,-51.96,;30.97,-50.17,;32,-49.03,;31.53,-47.56,;32.56,-46.41,;32.09,-44.94,;30.58,-44.63,;29.54,-45.77,;30.01,-47.24,;30.1,-43.16,;31.01,-41.9,;30.1,-40.65,;30.58,-39.19,;29.67,-37.94,;30.58,-36.7,;30.27,-35.2,;31.41,-34.17,;32.87,-34.65,;33.19,-36.15,;32.04,-37.18,;32.04,-38.72,;28.62,-41.13,;27.29,-40.37,;27.29,-38.83,;25.96,-41.14,;25.96,-42.68,;27.29,-43.45,;28.63,-42.68,)| Show InChI InChI=1S/C23H26N6O/c1-14(30)26-13-15-6-8-16(9-7-15)23-28-20(21-22(24)25-10-11-29(21)23)19-12-17-4-2-3-5-18(17)27-19/h2-5,10-12,15-16,27H,6-9,13H2,1H3,(H2,24,25)(H,26,30)/t15-,16-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of PDK1				Bioorg Med Chem Lett 21: 2092-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.139 BindingDB Entry DOI: 10.7270/Q23N23QH
					More data for this Ligand-Target Pair
Insulin receptor (Homo sapiens (Human))	BDBM50340954 (CHEMBL1762110 | Trans-N-((-4-(8-amino-1-(1H-indol-...) Show SMILES CC(=O)NC[C@H]1CC[C@@H](CC1)c1nc(-c2cc3ccccc3[nH]2)c2c(N)nccn12 |r,wU:8.11,wD:5.4,(30.4,-52.78,;31.44,-51.63,;32.94,-51.96,;30.97,-50.17,;32,-49.03,;31.53,-47.56,;32.56,-46.41,;32.09,-44.94,;30.58,-44.63,;29.54,-45.77,;30.01,-47.24,;30.1,-43.16,;31.01,-41.9,;30.1,-40.65,;30.58,-39.19,;29.67,-37.94,;30.58,-36.7,;30.27,-35.2,;31.41,-34.17,;32.87,-34.65,;33.19,-36.15,;32.04,-37.18,;32.04,-38.72,;28.62,-41.13,;27.29,-40.37,;27.29,-38.83,;25.96,-41.14,;25.96,-42.68,;27.29,-43.45,;28.63,-42.68,)| Show InChI InChI=1S/C23H26N6O/c1-14(30)26-13-15-6-8-16(9-7-15)23-28-20(21-22(24)25-10-11-29(21)23)19-12-17-4-2-3-5-18(17)27-19/h2-5,10-12,15-16,27H,6-9,13H2,1H3,(H2,24,25)(H,26,30)/t15-,16-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of IR				Bioorg Med Chem Lett 21: 2092-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.139 BindingDB Entry DOI: 10.7270/Q23N23QH
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50340952 (4-(8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-...) Show SMILES CN(C)C(=O)N1CCC(CC1)c1nc(-c2cc3ccccc3[nH]2)c2c(N)nccn12 Show InChI InChI=1S/C22H25N7O/c1-27(2)22(30)28-10-7-14(8-11-28)21-26-18(19-20(23)24-9-12-29(19)21)17-13-15-5-3-4-6-16(15)25-17/h3-6,9,12-14,25H,7-8,10-11H2,1-2H3,(H2,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of IGF-1R by ELISA				Bioorg Med Chem Lett 21: 2092-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.139 BindingDB Entry DOI: 10.7270/Q23N23QH
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50340952 (4-(8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-...) Show SMILES CN(C)C(=O)N1CCC(CC1)c1nc(-c2cc3ccccc3[nH]2)c2c(N)nccn12 Show InChI InChI=1S/C22H25N7O/c1-27(2)22(30)28-10-7-14(8-11-28)21-26-18(19-20(23)24-9-12-29(19)21)17-13-15-5-3-4-6-16(15)25-17/h3-6,9,12-14,25H,7-8,10-11H2,1-2H3,(H2,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma				Bioorg Med Chem Lett 21: 2092-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.139 BindingDB Entry DOI: 10.7270/Q23N23QH
					More data for this Ligand-Target Pair
Insulin receptor (Homo sapiens (Human))	BDBM50340952 (4-(8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-...) Show SMILES CN(C)C(=O)N1CCC(CC1)c1nc(-c2cc3ccccc3[nH]2)c2c(N)nccn12 Show InChI InChI=1S/C22H25N7O/c1-27(2)22(30)28-10-7-14(8-11-28)21-26-18(19-20(23)24-9-12-29(19)21)17-13-15-5-3-4-6-16(15)25-17/h3-6,9,12-14,25H,7-8,10-11H2,1-2H3,(H2,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of IR				Bioorg Med Chem Lett 21: 2092-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.139 BindingDB Entry DOI: 10.7270/Q23N23QH
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50340952 (4-(8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-...) Show SMILES CN(C)C(=O)N1CCC(CC1)c1nc(-c2cc3ccccc3[nH]2)c2c(N)nccn12 Show InChI InChI=1S/C22H25N7O/c1-27(2)22(30)28-10-7-14(8-11-28)21-26-18(19-20(23)24-9-12-29(19)21)17-13-15-5-3-4-6-16(15)25-17/h3-6,9,12-14,25H,7-8,10-11H2,1-2H3,(H2,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of PDK1				Bioorg Med Chem Lett 21: 2092-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.139 BindingDB Entry DOI: 10.7270/Q23N23QH
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50340954 (CHEMBL1762110 | Trans-N-((-4-(8-amino-1-(1H-indol-...) Show SMILES CC(=O)NC[C@H]1CC[C@@H](CC1)c1nc(-c2cc3ccccc3[nH]2)c2c(N)nccn12 |r,wU:8.11,wD:5.4,(30.4,-52.78,;31.44,-51.63,;32.94,-51.96,;30.97,-50.17,;32,-49.03,;31.53,-47.56,;32.56,-46.41,;32.09,-44.94,;30.58,-44.63,;29.54,-45.77,;30.01,-47.24,;30.1,-43.16,;31.01,-41.9,;30.1,-40.65,;30.58,-39.19,;29.67,-37.94,;30.58,-36.7,;30.27,-35.2,;31.41,-34.17,;32.87,-34.65,;33.19,-36.15,;32.04,-37.18,;32.04,-38.72,;28.62,-41.13,;27.29,-40.37,;27.29,-38.83,;25.96,-41.14,;25.96,-42.68,;27.29,-43.45,;28.63,-42.68,)| Show InChI InChI=1S/C23H26N6O/c1-14(30)26-13-15-6-8-16(9-7-15)23-28-20(21-22(24)25-10-11-29(21)23)19-12-17-4-2-3-5-18(17)27-19/h2-5,10-12,15-16,27H,6-9,13H2,1H3,(H2,24,25)(H,26,30)/t15-,16-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma				Bioorg Med Chem Lett 21: 2092-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.139 BindingDB Entry DOI: 10.7270/Q23N23QH
					More data for this Ligand-Target Pair