Found 832 hits with Last Name = 'shimizu' and Initial = 't' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Leukotriene B4 receptor 2
(Homo sapiens (Human)) | BDBM81521
(20-OH-LTB4 | CAS_1589 | NSC_1589)Show SMILES OCCCCCC=CCC(O)C=CC=CC=CC(O)CCCC(O)=O |w:6.5,11.10,13.12,15.14| Show InChI InChI=1S/C20H32O5/c21-17-10-6-2-1-3-7-12-18(22)13-8-4-5-9-14-19(23)15-11-16-20(24)25/h3-5,7-9,13-14,18-19,21-23H,1-2,6,10-12,15-17H2,(H,24,25) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo
Curated by PDSP Ki Database
| |
Nature 387: 620-4 (1997)
Article DOI: 10.1038/42506
BindingDB Entry DOI: 10.7270/Q2TH8K7F |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 2
(Homo sapiens (Human)) | BDBM85081
(12-oxo-LTB4 | CAS_5280876 | NSC_5280876)Show SMILES CCCCCCC=CC(=O)C=CC=CC=CC(O)CCCC(O)=O |w:6.5,10.9,12.11,14.13| Show InChI InChI=1S/C20H30O4/c1-2-3-4-5-6-9-13-18(21)14-10-7-8-11-15-19(22)16-12-17-20(23)24/h7-11,13-15,19,22H,2-6,12,16-17H2,1H3,(H,23,24) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo
Curated by PDSP Ki Database
| |
Nature 387: 620-4 (1997)
Article DOI: 10.1038/42506
BindingDB Entry DOI: 10.7270/Q2TH8K7F |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(RAT) | BDBM82213
(CAS_41598-07-6 | NSC_114678 | PGD2)Show SMILES CCCCCC(O)CC=C1C(CC=CCCCC(O)=O)C=CC1=O |w:8.7,12.11,c:20| Show InChI InChI=1S/C20H30O4/c1-2-3-6-10-17(21)13-14-18-16(12-15-19(18)22)9-7-4-5-8-11-20(23)24/h4,7,12,14-17,21H,2-3,5-6,8-11,13H2,1H3,(H,23,24) | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
PDB
UniChem
| PubMed
| 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University
Curated by PDSP Ki Database
| |
J Biol Chem 257: 13570-5 (1982)
BindingDB Entry DOI: 10.7270/Q22F7KXH |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(RAT) | BDBM82214
(CAS_114676 | NSC_114676 | PGD2-methyl ester)Show SMILES CCCCCC(O)C=CC1C(CC=CCCCC(=O)OC)C(O)CC1=O |w:7.6,12.11| Show InChI InChI=1S/C21H34O5/c1-3-4-7-10-16(22)13-14-18-17(19(23)15-20(18)24)11-8-5-6-9-12-21(25)26-2/h5,8,13-14,16-19,22-23H,3-4,6-7,9-12,15H2,1-2H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| PubMed
| 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University
Curated by PDSP Ki Database
| |
J Biol Chem 257: 13570-5 (1982)
BindingDB Entry DOI: 10.7270/Q22F7KXH |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Mus musculus) | BDBM50118202
(6-(4-azido-2,3,5,6-tetrafluorobenzyloxy)-8-(tert-b...)Show SMILES C[C@@H]1C(=O)O[C@H]2[C@H](O)[C@@]34C5C[C@@H](C(C)(C)C)C33C(OC(=O)[C@@H]3OCc3c(F)c(F)c(N=[N+]=[N-])c(F)c3F)OC4(C(=O)O5)[C@@]12O Show InChI InChI=1S/C27H25F4N3O10/c1-7-19(36)42-17-16(35)25-10-5-9(23(2,3)4)24(25)18(20(37)43-22(24)44-27(25,21(38)41-10)26(7,17)39)40-6-8-11(28)13(30)15(33-34-32)14(31)12(8)29/h7,9-10,16-18,22,35,39H,5-6H2,1-4H3/t7-,9+,10?,16+,17+,18+,22?,24?,25+,26-,27?/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description
Displacement of [3H]-WEB 2086 from Platelet activating factor receptor (PAF) |
J Med Chem 45: 4038-46 (2002)
BindingDB Entry DOI: 10.7270/Q29G5M5T |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50123637
(6-benzyloxy-8-(tert-butyl)-9-flouro-12,17-dihydrox...)Show SMILES C[C@@H]1C(=O)OC2[C@H](O)C34C5OC(=O)C3(OC3OC(=O)[C@H](OCc6ccccc6)C43C([C@H]5F)C(C)(C)C)[C@@]12O Show InChI InChI=1S/C27H29FO10/c1-11-19(30)35-17-15(29)25-16-13(28)14(23(2,3)4)24(25)18(34-10-12-8-6-5-7-9-12)20(31)37-22(24)38-27(25,21(32)36-16)26(11,17)33/h5-9,11,13-18,22,29,33H,10H2,1-4H3/t11-,13-,14?,15+,16?,17?,18+,22?,24?,25?,26-,27?/m1/s1 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description
Displacement of [3H]-WEB 2086 from Platelet activating factor receptor (guinea pig) transgenic mouse muscle membrane |
J Med Chem 46: 601-8 (2003)
Article DOI: 10.1021/jm0203985
BindingDB Entry DOI: 10.7270/Q2CC1023 |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50123639
(8-(tert-butyl)-9-chloro-6,12,17-trihydroxy-16-meth...)Show SMILES C[C@@H]1C(=O)OC2[C@H](O)C34C5OC(=O)C3(OC3OC(=O)[C@H](O)C43C([C@H]5Cl)C(C)(C)C)[C@@]12O Show InChI InChI=1S/C20H23ClO10/c1-5-12(24)28-11-8(22)18-10-6(21)7(16(2,3)4)17(18)9(23)13(25)30-15(17)31-20(18,14(26)29-10)19(5,11)27/h5-11,15,22-23,27H,1-4H3/t5-,6-,7?,8+,9+,10?,11?,15?,17?,18?,19-,20?/m1/s1 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description
Displacement of [3H]-WEB 2086 from Platelet activating factor receptor (guinea pig) transgenic mouse muscle membrane |
J Med Chem 46: 601-8 (2003)
Article DOI: 10.1021/jm0203985
BindingDB Entry DOI: 10.7270/Q2CC1023 |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50123644
(6-benzyloxy-8-(tert-butyl)-12,17-dihydroxy-16-meth...)Show SMILES C[C@@H]1C(=O)OC2[C@H](O)C34C5CC(C(C)(C)C)C33C(OC(=O)[C@@H]3OCc3ccccc3)OC4(C(=O)O5)[C@@]12O Show InChI InChI=1S/C27H30O10/c1-12-19(29)35-17-16(28)25-15-10-14(23(2,3)4)24(25)18(33-11-13-8-6-5-7-9-13)20(30)36-22(24)37-27(25,21(31)34-15)26(12,17)32/h5-9,12,14-18,22,28,32H,10-11H2,1-4H3/t12-,14?,15?,16+,17?,18+,22?,24?,25?,26-,27?/m1/s1 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description
Displacement of [3H]-WEB 2086 from Platelet activating factor receptor (guinea pig) transgenic mouse muscle membrane |
J Med Chem 46: 601-8 (2003)
Article DOI: 10.1021/jm0203985
BindingDB Entry DOI: 10.7270/Q2CC1023 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 2
(Homo sapiens (Human)) | BDBM79408
((5R)-6-[6-[(1E,3S,5Z)-3-hydroxyundeca-1,5-dienyl]-...)Show SMILES CCCCC\C=C/C[C@H](O)\C=C\c1cccc(C[C@H](O)CCCCO)n1 Show InChI InChI=1S/C22H35NO3/c1-2-3-4-5-6-7-13-21(25)16-15-19-11-10-12-20(23-19)18-22(26)14-8-9-17-24/h6-7,10-12,15-16,21-22,24-26H,2-5,8-9,13-14,17-18H2,1H3/b7-6-,16-15+/t21-,22+/m0/s1 | UniProtKB/SwissProt
antibodypedia
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| Purchase
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo
Curated by PDSP Ki Database
| |
Nature 387: 620-4 (1997)
Article DOI: 10.1038/42506
BindingDB Entry DOI: 10.7270/Q2TH8K7F |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Mus musculus) | BDBM50118204
(6-(4-benzoylphenylcarbonyloxy)-8-(tert-butyl)-12,1...)Show SMILES C[C@@H]1C(=O)O[C@H]2[C@H](O)[C@@]34C5C[C@@H](C(C)(C)C)C33C(OC(=O)[C@@H]3OC(=O)c3ccc(cc3)C(=O)c3ccccc3)OC4(C(=O)O5)[C@@]12O Show InChI InChI=1S/C34H32O12/c1-15-25(37)43-23-22(36)32-20-14-19(30(2,3)4)31(32)24(27(39)45-29(31)46-34(32,28(40)42-20)33(15,23)41)44-26(38)18-12-10-17(11-13-18)21(35)16-8-6-5-7-9-16/h5-13,15,19-20,22-24,29,36,41H,14H2,1-4H3/t15-,19+,20?,22+,23+,24+,29?,31?,32+,33-,34?/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description
Displacement of [3H]-WEB 2086 from Platelet activating factor receptor (PAF) |
J Med Chem 45: 4038-46 (2002)
BindingDB Entry DOI: 10.7270/Q29G5M5T |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Mus musculus) | BDBM50118194
(8-(tert-butyl)-12,17-dihydroxy-16-methyl-6-[4-(3-t...)Show SMILES C[C@@H]1C(=O)O[C@H]2[C@H](O)[C@@]34C5C[C@@H](C(C)(C)C)C33C(OC(=O)[C@@H]3OCc3ccc(cc3)C3(N=N3)C(F)(F)F)OC4(C(=O)O5)[C@@]12O |c:34| Show InChI InChI=1S/C29H29F3N2O10/c1-11-19(36)42-17-16(35)25-15-9-14(23(2,3)4)24(25)18(20(37)43-22(24)44-27(25,21(38)41-15)26(11,17)39)40-10-12-5-7-13(8-6-12)28(33-34-28)29(30,31)32/h5-8,11,14-18,22,35,39H,9-10H2,1-4H3/t11-,14+,15?,16+,17+,18+,22?,24?,25+,26-,27?/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description
Displacement of [3H]-WEB 2086 from Platelet activating factor receptor (PAF) |
J Med Chem 45: 4038-46 (2002)
BindingDB Entry DOI: 10.7270/Q29G5M5T |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Mus musculus) | BDBM50118201
(6-(4-benzoylbenzyloxy)-8-(tert-butyl)-12,17-dihydr...)Show SMILES C[C@@H]1C(=O)O[C@H]2[C@H](O)[C@@]34C5C[C@@H](C(C)(C)C)C33C(OC(=O)[C@@H]3OCc3ccc(cc3)C(=O)c3ccccc3)OC4(C(=O)O5)[C@@]12O Show InChI InChI=1S/C34H34O11/c1-16-26(37)43-24-23(36)32-21-14-20(30(2,3)4)31(32)25(27(38)44-29(31)45-34(32,28(39)42-21)33(16,24)40)41-15-17-10-12-19(13-11-17)22(35)18-8-6-5-7-9-18/h5-13,16,20-21,23-25,29,36,40H,14-15H2,1-4H3/t16-,20+,21?,23+,24+,25+,29?,31?,32+,33-,34?/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description
Displacement of [3H]-WEB 2086 from Platelet activating factor receptor (PAF) |
J Med Chem 45: 4038-46 (2002)
BindingDB Entry DOI: 10.7270/Q29G5M5T |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 2
(Homo sapiens (Human)) | BDBM85082
(20-COOH-LTB4 | CAS_128572 | NSC_128572)Show SMILES OC(CCCC(O)=O)C=CC=CC=CC(O)CC=CCCCCCC(O)=O |w:18.18,13.13,11.11,9.9| Show InChI InChI=1S/C21H32O6/c22-18(12-7-3-1-2-4-10-16-20(24)25)13-8-5-6-9-14-19(23)15-11-17-21(26)27/h3,5-9,13-14,18-19,22-23H,1-2,4,10-12,15-17H2,(H,24,25)(H,26,27) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo
Curated by PDSP Ki Database
| |
Nature 387: 620-4 (1997)
Article DOI: 10.1038/42506
BindingDB Entry DOI: 10.7270/Q2TH8K7F |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Mus musculus) | BDBM50118203
(8-(tert-butyl)-9,12,17-trihydroxy-16-methyl-6-[4-(...)Show SMILES C[C@@H]1C(=O)O[C@H]2[C@H](O)[C@]34C5OC(=O)C3(OC3OC(=O)[C@H](OCc6ccc(cc6)C6(N=N6)C(F)(F)F)C43[C@@H]([C@H]5O)C(C)(C)C)[C@@]12O |c:31| Show InChI InChI=1S/C29H29F3N2O11/c1-10-19(37)42-17-15(36)25-16-13(35)14(23(2,3)4)24(25)18(20(38)44-22(24)45-27(25,21(39)43-16)26(10,17)40)41-9-11-5-7-12(8-6-11)28(33-34-28)29(30,31)32/h5-8,10,13-18,22,35-36,40H,9H2,1-4H3/t10-,13-,14+,15+,16?,17+,18+,22?,24?,25-,26-,27?/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description
Displacement of [3H]-WEB 2086 from Platelet activating factor receptor (PAF) |
J Med Chem 45: 4038-46 (2002)
BindingDB Entry DOI: 10.7270/Q29G5M5T |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(RAT) | BDBM82209
(CAS_205449 | NSC_205449 | PGD1)Show SMILES CCCCCC(O)C=CC1C(CCCCCCC(O)=O)C(O)CC1=O |w:7.6| Show InChI InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-18,21-22H,2-11,14H2,1H3,(H,24,25) | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 523 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University
Curated by PDSP Ki Database
| |
J Biol Chem 257: 13570-5 (1982)
BindingDB Entry DOI: 10.7270/Q22F7KXH |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50123638
(9-azido-8-(tert-butyl)-6,12,17-trihydroxy-16-methy...)Show SMILES C[C@@H]1C(=O)OC2[C@H](O)C34C5OC(=O)C3(OC3OC(=O)[C@H](O)C43C([C@H]5N=[N+]=[N-])C(C)(C)C)[C@@]12O Show InChI InChI=1S/C20H23N3O10/c1-5-12(26)30-11-8(24)18-10-6(22-23-21)7(16(2,3)4)17(18)9(25)13(27)32-15(17)33-20(18,14(28)31-10)19(5,11)29/h5-11,15,24-25,29H,1-4H3/t5-,6-,7?,8+,9+,10?,11?,15?,17?,18?,19-,20?/m1/s1 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 550 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description
Displacement of [3H]-WEB 2086 from Platelet activating factor receptor (guinea pig) transgenic mouse muscle membrane |
J Med Chem 46: 601-8 (2003)
Article DOI: 10.1021/jm0203985
BindingDB Entry DOI: 10.7270/Q2CC1023 |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Mus musculus) | BDBM50118195
(3'-(tert-butyl)-4,9',14'-trihydroxy-2-methoxy-10'-...)Show SMILES COC1OC(=O)[C@H](O)C11[C@@H](CC2OC(=O)C3[C@@]4(O)[C@H](C)C(=O)O[C@H]4[C@H](O)[C@]123)C(C)(C)C Show InChI InChI=1S/C21H28O10/c1-7-14(24)30-13-11(22)20-9(29-15(25)10(20)21(7,13)27)6-8(18(2,3)4)19(20)12(23)16(26)31-17(19)28-5/h7-13,17,22-23,27H,6H2,1-5H3/t7-,8+,9?,10?,11+,12+,13+,17?,19?,20+,21+/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 560 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description
Displacement of [3H]-WEB 2086 from Platelet activating factor receptor (PAF) |
J Med Chem 45: 4038-46 (2002)
BindingDB Entry DOI: 10.7270/Q29G5M5T |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Mus musculus) | BDBM50118196
(6-(4-benzoylbenzyloxy)-8-(tert-butyl)-9,12,17-trih...)Show SMILES C[C@@H]1C(=O)O[C@H]2[C@H](O)[C@]34C5OC(=O)C3(OC3OC(=O)[C@H](OCc6ccc(cc6)C(=O)c6ccccc6)C43[C@@H]([C@H]5O)C(C)(C)C)[C@@]12O Show InChI InChI=1S/C34H34O12/c1-15-26(38)43-24-22(37)32-23-20(36)21(30(2,3)4)31(32)25(27(39)45-29(31)46-34(32,28(40)44-23)33(15,24)41)42-14-16-10-12-18(13-11-16)19(35)17-8-6-5-7-9-17/h5-13,15,20-25,29,36-37,41H,14H2,1-4H3/t15-,20-,21+,22+,23?,24+,25+,29?,31?,32-,33-,34?/m1/s1 | Reactome pathway
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UniChem
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| 580 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description
Displacement of [3H]-WEB 2086 from Platelet activating factor receptor (PAF) |
J Med Chem 45: 4038-46 (2002)
BindingDB Entry DOI: 10.7270/Q29G5M5T |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50123643
(6-benzyloxy-8-(tert-butyl)-9,12,17-trihydroxy-16-m...)Show SMILES C[C@@H]1C(=O)OC2[C@H](O)C34C5OC(=O)C3(OC3OC(=O)[C@H](OCc6ccccc6)C43C([C@H]5O)C(C)(C)C)[C@@]12O Show InChI InChI=1S/C27H30O11/c1-11-19(30)35-17-15(29)25-16-13(28)14(23(2,3)4)24(25)18(34-10-12-8-6-5-7-9-12)20(31)37-22(24)38-27(25,21(32)36-16)26(11,17)33/h5-9,11,13-18,22,28-29,33H,10H2,1-4H3/t11-,13-,14?,15+,16?,17?,18+,22?,24?,25?,26-,27?/m1/s1 | MMDB
Reactome pathway
KEGG
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| CHEMBL
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PC sid
UniChem
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PubMed
| 600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description
Displacement of [3H]-WEB 2086 from Platelet activating factor receptor (guinea pig) transgenic mouse muscle membrane |
J Med Chem 46: 601-8 (2003)
Article DOI: 10.1021/jm0203985
BindingDB Entry DOI: 10.7270/Q2CC1023 |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50123633
(8-(tert-butyl)-6,12,17-trihydroxy-16-methyl-9-meth...)Show SMILES CN[C@H]1C2OC(=O)C34OC5OC(=O)[C@H](O)C5(C1C(C)(C)C)C23[C@@H](O)C1OC(=O)[C@@H](C)[C@]41O Show InChI InChI=1S/C21H27NO10/c1-6-13(25)29-12-9(23)19-11-7(22-5)8(17(2,3)4)18(19)10(24)14(26)31-16(18)32-21(19,15(27)30-11)20(6,12)28/h6-12,16,22-24,28H,1-5H3/t6-,7-,8?,9+,10+,11?,12?,16?,18?,19?,20-,21?/m1/s1 | MMDB
Reactome pathway
KEGG
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B.MOAD
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| CHEMBL
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PC sid
UniChem
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PubMed
| 610 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description
Displacement of [3H]-WEB 2086 from Platelet activating factor receptor (guinea pig) transgenic mouse muscle membrane |
J Med Chem 46: 601-8 (2003)
Article DOI: 10.1021/jm0203985
BindingDB Entry DOI: 10.7270/Q2CC1023 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(RAT) | BDBM50020300
((S-isomer)7-[3,5-Dihydroxy-2-(3-hydroxy-oct-1-enyl...)Show SMILES CCCCC[C@H](O)\C=C\C1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O Show InChI InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17?,18-,19+/m0/s1 | KEGG
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| 693 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University
Curated by PDSP Ki Database
| |
J Biol Chem 257: 13570-5 (1982)
BindingDB Entry DOI: 10.7270/Q22F7KXH |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Mus musculus) | BDBM50118200
(6-(4-azido-2,3,5,6-tetrafluorobenzyloxy)-8-(tert-b...)Show SMILES C[C@@H]1C(=O)O[C@H]2[C@H](O)[C@]34C5OC(=O)C3(OC3OC(=O)[C@H](OCc6c(F)c(F)c(N=[N+]=[N-])c(F)c6F)C43[C@@H]([C@H]5O)C(C)(C)C)[C@@]12O Show InChI InChI=1S/C27H25F4N3O11/c1-6-19(37)42-17-15(36)25-16-13(35)14(23(2,3)4)24(25)18(20(38)44-22(24)45-27(25,21(39)43-16)26(6,17)40)41-5-7-8(28)10(30)12(33-34-32)11(31)9(7)29/h6,13-18,22,35-36,40H,5H2,1-4H3/t6-,13-,14+,15+,16?,17+,18+,22?,24?,25-,26-,27?/m1/s1 | Reactome pathway
KEGG
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GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
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| 790 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description
Displacement of [3H]-WEB 2086 from Platelet activating factor receptor (PAF) |
J Med Chem 45: 4038-46 (2002)
BindingDB Entry DOI: 10.7270/Q29G5M5T |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50251276
(BN 52021 | CHEMBL514432 | GINKOLIDE B | Gingkolide...)Show SMILES C[C@@H]1C(=O)O[C@H]2[C@H](O)[C@@]34[C@H]5C[C@@H](C(C)(C)C)[C@@]33[C@@H](O)C(=O)O[C@H]3O[C@@]4(C(=O)O5)[C@@]12O |r| Show InChI InChI=1S/C20H24O10/c1-6-12(23)28-11-9(21)18-8-5-7(16(2,3)4)17(18)10(22)13(24)29-15(17)30-20(18,14(25)27-8)19(6,11)26/h6-11,15,21-22,26H,5H2,1-4H3/t6-,7+,8-,9+,10+,11+,15+,17+,18+,19-,20-/m1/s1 | MMDB
Reactome pathway
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PubMed
| 880 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description
Displacement of [3H]-WEB 2086 from Platelet activating factor receptor (guinea pig) transgenic mouse muscle membrane |
J Med Chem 46: 601-8 (2003)
Article DOI: 10.1021/jm0203985
BindingDB Entry DOI: 10.7270/Q2CC1023 |
More data for this
Ligand-Target Pair | |
Beta-galactosidase [24-677,R201C]
(Homo sapiens (Human)) | BDBM228800
(NOEV | Sapienic acid (SpA))Show SMILES CCCCCCCCN[C@H]1C=C(CO)[C@@H](O)[C@H](O)[C@H]1O |t:10| Show InChI InChI=1S/C15H29NO4/c1-2-3-4-5-6-7-8-16-12-9-11(10-17)13(18)15(20)14(12)19/h9,12-20H,2-8,10H2,1H3/t12-,13+,14-,15-/m0/s1 | PDB
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| PC cid
PC sid
UniChem
| Article
PubMed
| 940 | -35.8 | n/a | n/a | n/a | n/a | n/a | 4.5 | 37 |
The University of Tokyo
| Assay Description
β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl... |
J Biol Chem 289: 14560-8 (2014)
Article DOI: 10.1074/jbc.M113.529529
BindingDB Entry DOI: 10.7270/Q2WH2NW4 |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50123642
(8-(tert-butyl)-9-flouro-6,12,17-trihydroxy-16-meth...)Show SMILES C[C@@H]1C(=O)OC2[C@H](O)C34C5OC(=O)C3(OC3OC(=O)[C@H](O)C43C([C@H]5F)C(C)(C)C)[C@@]12O Show InChI InChI=1S/C20H23FO10/c1-5-12(24)28-11-8(22)18-10-6(21)7(16(2,3)4)17(18)9(23)13(25)30-15(17)31-20(18,14(26)29-10)19(5,11)27/h5-11,15,22-23,27H,1-4H3/t5-,6-,7?,8+,9+,10?,11?,15?,17?,18?,19-,20?/m1/s1 | MMDB
Reactome pathway
KEGG
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| CHEMBL
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PC sid
UniChem
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| Article
PubMed
| 990 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description
Displacement of [3H]-WEB 2086 from Platelet activating factor receptor (guinea pig) transgenic mouse muscle membrane |
J Med Chem 46: 601-8 (2003)
Article DOI: 10.1021/jm0203985
BindingDB Entry DOI: 10.7270/Q2CC1023 |
More data for this
Ligand-Target Pair | |
Beta-galactosidase [24-677]
(Homo sapiens (Human)) | BDBM228800
(NOEV | Sapienic acid (SpA))Show SMILES CCCCCCCCN[C@H]1C=C(CO)[C@@H](O)[C@H](O)[C@H]1O |t:10| Show InChI InChI=1S/C15H29NO4/c1-2-3-4-5-6-7-8-16-12-9-11(10-17)13(18)15(20)14(12)19/h9,12-20H,2-8,10H2,1H3/t12-,13+,14-,15-/m0/s1 | PDB
UniProtKB/SwissProt
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AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.10E+3 | -35.4 | n/a | n/a | n/a | n/a | n/a | 4.5 | 37 |
The University of Tokyo
| Assay Description
β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl... |
J Biol Chem 289: 14560-8 (2014)
Article DOI: 10.1074/jbc.M113.529529
BindingDB Entry DOI: 10.7270/Q2WH2NW4 |
More data for this
Ligand-Target Pair | |
Beta-galactosidase [24-677,I51T]
(Homo sapiens (Human)) | BDBM228800
(NOEV | Sapienic acid (SpA))Show SMILES CCCCCCCCN[C@H]1C=C(CO)[C@@H](O)[C@H](O)[C@H]1O |t:10| Show InChI InChI=1S/C15H29NO4/c1-2-3-4-5-6-7-8-16-12-9-11(10-17)13(18)15(20)14(12)19/h9,12-20H,2-8,10H2,1H3/t12-,13+,14-,15-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.20E+3 | -35.2 | n/a | n/a | n/a | n/a | n/a | 4.5 | 37 |
The University of Tokyo
| Assay Description
β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl... |
J Biol Chem 289: 14560-8 (2014)
Article DOI: 10.1074/jbc.M113.529529
BindingDB Entry DOI: 10.7270/Q2WH2NW4 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 2
(Homo sapiens (Human)) | BDBM50037382
(5-{2-(2-Carboxy-ethyl)-3-[(E)-6-(4-methoxy-phenyl)...)Show SMILES COc1ccc(\C=C\CCCCOc2cccc(OCCCCC(O)=O)c2CCC(O)=O)cc1 Show InChI InChI=1S/C27H34O7/c1-32-22-15-13-21(14-16-22)9-4-2-3-6-19-33-24-10-8-11-25(23(24)17-18-27(30)31)34-20-7-5-12-26(28)29/h4,8-11,13-16H,2-3,5-7,12,17-20H2,1H3,(H,28,29)(H,30,31)/b9-4+ | UniProtKB/SwissProt
antibodypedia
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| 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokyo
Curated by PDSP Ki Database
| |
Nature 387: 620-4 (1997)
Article DOI: 10.1038/42506
BindingDB Entry DOI: 10.7270/Q2TH8K7F |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Mus musculus) | BDBM50118205
(3'-(tert-butyl)-4,9'-dihydroxy-2-methoxy-10'-methy...)Show SMILES COC1OC(=O)[C@H](O)C11[C@@H](CC2OC(=O)C3[C@@]4(O)[C@H](C)C(=O)O[C@H]4C[C@]123)C(C)(C)C Show InChI InChI=1S/C21H28O9/c1-8-14(23)29-11-7-19-10(28-15(24)12(19)21(8,11)26)6-9(18(2,3)4)20(19)13(22)16(25)30-17(20)27-5/h8-13,17,22,26H,6-7H2,1-5H3/t8-,9+,10?,11+,12?,13+,17?,19+,20?,21-/m1/s1 | Reactome pathway
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| 1.46E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description
Displacement of [3H]-WEB 2086 from Platelet activating factor receptor (PAF) |
J Med Chem 45: 4038-46 (2002)
BindingDB Entry DOI: 10.7270/Q29G5M5T |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50123631
(8-(tert-butyl)-6,12,17-trihydroxy-16-methyl-9-ethy...)Show SMILES CCN[C@H]1C2OC(=O)C34OC5OC(=O)[C@H](O)C5(C1C(C)(C)C)C23[C@@H](O)C1OC(=O)[C@@H](C)[C@]41O Show InChI InChI=1S/C22H29NO10/c1-6-23-8-9(18(3,4)5)19-11(25)15(27)32-17(19)33-22-16(28)31-12(8)20(19,22)10(24)13-21(22,29)7(2)14(26)30-13/h7-13,17,23-25,29H,6H2,1-5H3/t7-,8-,9?,10+,11+,12?,13?,17?,19?,20?,21-,22?/m1/s1 | MMDB
Reactome pathway
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UniChem
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| 1.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description
Displacement of [3H]-WEB 2086 from Platelet activating factor receptor (guinea pig) transgenic mouse muscle membrane |
J Med Chem 46: 601-8 (2003)
Article DOI: 10.1021/jm0203985
BindingDB Entry DOI: 10.7270/Q2CC1023 |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50123632
(6-benzyloxy-8-(tert-butyl)-9,12,17-trihydroxy-16-m...)Show SMILES C[C@@H]1C(=O)OC2[C@H](O)C34C5OC(=O)C3(OC3OC(=O)[C@H](OCc6ccccc6)C43C([C@@H]5O)C(C)(C)C)[C@@]12O Show InChI InChI=1S/C27H30O11/c1-11-19(30)35-17-15(29)25-16-13(28)14(23(2,3)4)24(25)18(34-10-12-8-6-5-7-9-12)20(31)37-22(24)38-27(25,21(32)36-16)26(11,17)33/h5-9,11,13-18,22,28-29,33H,10H2,1-4H3/t11-,13+,14?,15+,16?,17?,18+,22?,24?,25?,26-,27?/m1/s1 | MMDB
Reactome pathway
KEGG
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PC sid
UniChem
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PubMed
| 1.67E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description
Displacement of [3H]-WEB 2086 from Platelet activating factor receptor (guinea pig) transgenic mouse muscle membrane |
J Med Chem 46: 601-8 (2003)
Article DOI: 10.1021/jm0203985
BindingDB Entry DOI: 10.7270/Q2CC1023 |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50123645
(CHEMBL348623 | benzyl (6R,9R,12R,16S,17R)-8-tert-b...)Show SMILES C[C@@H]1C(=O)OC2[C@H](O)C34C5OC(=O)C3(OC3OC(=O)[C@H](O)C43C([C@H]5OC(=O)OCc3ccccc3)C(C)(C)C)[C@@]12O Show InChI InChI=1S/C28H30O13/c1-11-19(31)38-18-15(29)26-17-13(37-23(34)36-10-12-8-6-5-7-9-12)14(24(2,3)4)25(26)16(30)20(32)40-22(25)41-28(26,21(33)39-17)27(11,18)35/h5-9,11,13-18,22,29-30,35H,10H2,1-4H3/t11-,13-,14?,15+,16+,17?,18?,22?,25?,26?,27-,28?/m1/s1 | MMDB
Reactome pathway
KEGG
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| CHEMBL
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PC sid
UniChem
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PubMed
| 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description
Displacement of [3H]-WEB 2086 from Platelet activating factor receptor (guinea pig) transgenic mouse muscle membrane |
J Med Chem 46: 601-8 (2003)
Article DOI: 10.1021/jm0203985
BindingDB Entry DOI: 10.7270/Q2CC1023 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(RAT) | BDBM35847
((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O Show InChI InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m0/s1 | KEGG
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| 2.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University
Curated by PDSP Ki Database
| |
J Biol Chem 257: 13570-5 (1982)
BindingDB Entry DOI: 10.7270/Q22F7KXH |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(RAT) | BDBM82215
(CAS_35121-78-9 | NSC_5282411 | PGI2)Show SMILES CCCCCC(O)C=CC1C(O)CC2OC(CC12)=CCCCC(O)=O |w:7.6,18.20| Show InChI InChI=1S/C20H32O5/c1-2-3-4-7-14(21)10-11-16-17-12-15(8-5-6-9-20(23)24)25-19(17)13-18(16)22/h8,10-11,14,16-19,21-22H,2-7,9,12-13H2,1H3,(H,23,24) | KEGG
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| 3.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University
Curated by PDSP Ki Database
| |
J Biol Chem 257: 13570-5 (1982)
BindingDB Entry DOI: 10.7270/Q22F7KXH |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(RAT) | BDBM50101828
(7-[(1R,2R,3R)-3-Hydroxy-2-((E)-(R)-3-hydroxy-oct-1...)Show SMILES CCCCC[C@@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O Show InChI InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16-,17-,19-/m1/s1 | KEGG
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| 3.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University
Curated by PDSP Ki Database
| |
J Biol Chem 257: 13570-5 (1982)
BindingDB Entry DOI: 10.7270/Q22F7KXH |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(RAT) | BDBM82210
(CAS_54397-85-2 | PG Thromboxane B2 | THROMBOXANE B...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1OC(O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O |r| Show InChI InChI=1S/C20H34O6/c1-2-3-6-9-15(21)12-13-18-16(17(22)14-20(25)26-18)10-7-4-5-8-11-19(23)24/h4,7,12-13,15-18,20-22,25H,2-3,5-6,8-11,14H2,1H3,(H,23,24)/b7-4-,13-12+/t15-,16-,17-,18+,20?/m0/s1 | KEGG
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| 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University
Curated by PDSP Ki Database
| |
J Biol Chem 257: 13570-5 (1982)
BindingDB Entry DOI: 10.7270/Q22F7KXH |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50123635
(8-(tert-butyl)-6,9,12,17-tetrahydroxy-16-methyl-(6...)Show SMILES C[C@@H]1C(=O)OC2[C@H](O)C34C5OC(=O)C3(OC3OC(=O)[C@H](O)C43C([C@H]5O)C(C)(C)C)[C@@]12O Show InChI InChI=1S/C20H24O11/c1-5-12(24)28-11-8(22)18-10-6(21)7(16(2,3)4)17(18)9(23)13(25)30-15(17)31-20(18,14(26)29-10)19(5,11)27/h5-11,15,21-23,27H,1-4H3/t5-,6-,7?,8+,9+,10?,11?,15?,17?,18?,19-,20?/m1/s1 | MMDB
Reactome pathway
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| 4.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description
Displacement of [3H]-WEB 2086 from Platelet activating factor receptor (guinea pig) transgenic mouse muscle membrane |
J Med Chem 46: 601-8 (2003)
Article DOI: 10.1021/jm0203985
BindingDB Entry DOI: 10.7270/Q2CC1023 |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50123636
(8-(tert-butyl)-6,12,17-trihydroxy-16-methyl-5,15,1...)Show SMILES C[C@@H]1C(=O)OC2[C@H](O)C34C5OC(=O)C3(OC3OC(=O)[C@H](O)C43C([C@H]5OC(C)=O)C(C)(C)C)[C@@]12O Show InChI InChI=1S/C22H26O12/c1-6-14(26)31-13-10(24)20-12-8(30-7(2)23)9(18(3,4)5)19(20)11(25)15(27)33-17(19)34-22(20,16(28)32-12)21(6,13)29/h6,8-13,17,24-25,29H,1-5H3/t6-,8-,9?,10+,11+,12?,13?,17?,19?,20?,21-,22?/m1/s1 | MMDB
Reactome pathway
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| 7.84E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description
Displacement of [3H]-WEB 2086 from Platelet activating factor receptor (guinea pig) transgenic mouse muscle membrane |
J Med Chem 46: 601-8 (2003)
Article DOI: 10.1021/jm0203985
BindingDB Entry DOI: 10.7270/Q2CC1023 |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50123640
(8-(tert-butyl)-6,12,17-trihydroxy-16-methyl-9-amin...)Show SMILES C[C@@H]1C(=O)OC2[C@H](O)C34C5OC(=O)C3(OC3OC(=O)[C@H](O)C43C([C@H]5N)C(C)(C)C)[C@@]12O Show InChI InChI=1S/C20H25NO10/c1-5-12(24)28-11-8(22)18-10-6(21)7(16(2,3)4)17(18)9(23)13(25)30-15(17)31-20(18,14(26)29-10)19(5,11)27/h5-11,15,22-23,27H,21H2,1-4H3/t5-,6-,7?,8+,9+,10?,11?,15?,17?,18?,19-,20?/m1/s1 | MMDB
Reactome pathway
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PubMed
| 8.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description
Displacement of [3H]-WEB 2086 from Platelet activating factor receptor (guinea pig) transgenic mouse muscle membrane |
J Med Chem 46: 601-8 (2003)
Article DOI: 10.1021/jm0203985
BindingDB Entry DOI: 10.7270/Q2CC1023 |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Mus musculus) | BDBM50118193
(3'-(tert-butyl)-4,4',9'-trihydroxy-2-methoxy-10'-m...)Show SMILES COC1OC(=O)[C@H](O)C11[C@@H]([C@@H](O)C2OC(=O)C3[C@@]4(O)[C@H](C)C(=O)O[C@H]4C[C@]123)C(C)(C)C Show InChI InChI=1S/C21H28O10/c1-7-14(24)29-8-6-19-11(21(7,8)27)15(25)30-13(19)9(22)10(18(2,3)4)20(19)12(23)16(26)31-17(20)28-5/h7-13,17,22-23,27H,6H2,1-5H3/t7-,8+,9-,10+,11?,12+,13?,17?,19-,20?,21-/m1/s1 | Reactome pathway
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| 9.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description
Displacement of [3H]-WEB 2086 from Platelet activating factor receptor (PAF) |
J Med Chem 45: 4038-46 (2002)
BindingDB Entry DOI: 10.7270/Q29G5M5T |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(RAT) | BDBM82211
(6-KETO-PROSTAGLANDIN F1ALPHA | CAS_58962-34-8 | PG...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1CC(=O)CCCCC(O)=O |r| Show InChI InChI=1S/C20H34O6/c1-2-3-4-7-14(21)10-11-16-17(19(24)13-18(16)23)12-15(22)8-5-6-9-20(25)26/h10-11,14,16-19,21,23-24H,2-9,12-13H2,1H3,(H,25,26)/b11-10+/t14-,16+,17+,18+,19-/m0/s1 | KEGG
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| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University
Curated by PDSP Ki Database
| |
J Biol Chem 257: 13570-5 (1982)
BindingDB Entry DOI: 10.7270/Q22F7KXH |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(RAT) | BDBM34230
((Z)-7-[(1R,2S)-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-ke...)Show SMILES CCCCC[C@H](O)C=C[C@H]1C=CC(=O)[C@@H]1C\C=C/CCCC(O)=O |c:10| Show InChI InChI=1S/C20H30O4/c1-2-3-6-9-17(21)14-12-16-13-15-19(22)18(16)10-7-4-5-8-11-20(23)24/h4,7,12-18,21H,2-3,5-6,8-11H2,1H3,(H,23,24)/b7-4-,14-12?/t16-,17-,18+/m0/s1 | KEGG
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| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University
Curated by PDSP Ki Database
| |
J Biol Chem 257: 13570-5 (1982)
BindingDB Entry DOI: 10.7270/Q22F7KXH |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(RAT) | BDBM82212
(CAS_5280881 | NSC_5280881 | PGB2)Show SMILES CCCCCC(O)C=CC1=C(CC=CCCCC(O)=O)C(=O)CC1 |w:7.6,12.11,c:9| Show InChI InChI=1S/C20H30O4/c1-2-3-6-9-17(21)14-12-16-13-15-19(22)18(16)10-7-4-5-8-11-20(23)24/h4,7,12,14,17,21H,2-3,5-6,8-11,13,15H2,1H3,(H,23,24) | KEGG
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| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University
Curated by PDSP Ki Database
| |
J Biol Chem 257: 13570-5 (1982)
BindingDB Entry DOI: 10.7270/Q22F7KXH |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50123641
(8-(tert-butyl)-6,9,12,17-tetrahydroxy-16-methyl-(6...)Show SMILES C[C@@H]1C(=O)OC2[C@H](O)C34C5OC(=O)C3(OC3OC(=O)[C@H](O)C43C([C@@H]5O)C(C)(C)C)[C@@]12O Show InChI InChI=1S/C20H24O11/c1-5-12(24)28-11-8(22)18-10-6(21)7(16(2,3)4)17(18)9(23)13(25)30-15(17)31-20(18,14(26)29-10)19(5,11)27/h5-11,15,21-23,27H,1-4H3/t5-,6+,7?,8+,9+,10?,11?,15?,17?,18?,19-,20?/m1/s1 | MMDB
Reactome pathway
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| 1.26E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description
Displacement of [3H]-WEB 2086 from Platelet activating factor receptor (guinea pig) transgenic mouse muscle membrane |
J Med Chem 46: 601-8 (2003)
Article DOI: 10.1021/jm0203985
BindingDB Entry DOI: 10.7270/Q2CC1023 |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Mus musculus) | BDBM50118197
(3'-(tert-butyl)-4,4',9',14'-tetrahydroxy-2-methoxy...)Show SMILES COC1OC(=O)[C@H](O)C11[C@@H]([C@@H](O)C2OC(=O)C3[C@@]4(O)[C@H](C)C(=O)O[C@H]4[C@H](O)[C@]123)C(C)(C)C Show InChI InChI=1S/C21H28O11/c1-6-14(25)31-13-10(23)19-9(21(6,13)28)15(26)30-12(19)7(22)8(18(2,3)4)20(19)11(24)16(27)32-17(20)29-5/h6-13,17,22-24,28H,1-5H3/t6-,7-,8+,9?,10+,11+,12?,13+,17?,19+,20?,21+/m1/s1 | Reactome pathway
KEGG
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| CHEMBL
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PC sid
UniChem
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| 1.26E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description
Displacement of [3H]-WEB 2086 from Platelet activating factor receptor (PAF) |
J Med Chem 45: 4038-46 (2002)
BindingDB Entry DOI: 10.7270/Q29G5M5T |
More data for this
Ligand-Target Pair | |
Beta-galactosidase [24-677,I51T]
(Homo sapiens (Human)) | BDBM50163440
((2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-tr...)Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5+,6-/m1/s1 | PDB
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Article
PubMed
| 4.47E+4 | -25.8 | n/a | n/a | n/a | n/a | n/a | 4.5 | 37 |
The University of Tokyo
| Assay Description
β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl... |
J Biol Chem 289: 14560-8 (2014)
Article DOI: 10.1074/jbc.M113.529529
BindingDB Entry DOI: 10.7270/Q2WH2NW4 |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Beta-galactosidase [24-677,R201C]
(Homo sapiens (Human)) | BDBM50163440
((2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-tr...)Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5+,6-/m1/s1 | PDB
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Article
PubMed
| 4.90E+4 | -25.6 | n/a | n/a | n/a | n/a | n/a | 4.5 | 37 |
The University of Tokyo
| Assay Description
β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl... |
J Biol Chem 289: 14560-8 (2014)
Article DOI: 10.1074/jbc.M113.529529
BindingDB Entry DOI: 10.7270/Q2WH2NW4 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Platelet-activating factor receptor
(Mus musculus) | BDBM50118198
(3'-(tert-butyl)-4,4',14'-trihydroxy-2-methoxy-10'-...)Show SMILES COC1OC(=O)[C@H](O)C11[C@@H]([C@@H](O)C2OC(=O)C3[C@H]4[C@H](C)C(=O)O[C@H]4[C@H](O)[C@]123)C(C)(C)C Show InChI InChI=1S/C21H28O10/c1-6-7-8-16(26)30-14-9(22)11(19(2,3)4)21(13(24)17(27)31-18(21)28-5)20(8,14)12(23)10(7)29-15(6)25/h6-14,18,22-24H,1-5H3/t6-,7+,8?,9+,10+,11-,12-,13-,14?,18?,20-,21?/m0/s1 | Reactome pathway
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| >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description
Displacement of [3H]-WEB 2086 from Platelet activating factor receptor (PAF) |
J Med Chem 45: 4038-46 (2002)
BindingDB Entry DOI: 10.7270/Q29G5M5T |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Mus musculus) | BDBM50118199
(9-tert-Butyl-8,9-dihydroxy-dihydro-furo[2,3-b]furo...)Show SMILES CC(C)(C)[C@]1(O)CC2OC(=O)CC22C(=O)OC3OC(=O)[C@H](O)C123 Show InChI InChI=1S/C15H18O8/c1-12(2,3)14(20)4-6-13(5-7(16)21-6)10(19)23-11-15(13,14)8(17)9(18)22-11/h6,8,11,17,20H,4-5H2,1-3H3/t6?,8-,11?,13?,14+,15?/m0/s1 | Reactome pathway
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| >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description
Displacement of [3H]-WEB 2086 from Platelet activating factor receptor (PAF) |
J Med Chem 45: 4038-46 (2002)
BindingDB Entry DOI: 10.7270/Q29G5M5T |
More data for this
Ligand-Target Pair | |
Beta-galactosidase [24-677,R201C]
(Homo sapiens (Human)) | BDBM228802
(5N,6S-(N'-butyliminomethylidene)-6-thio-1-deox...)Show SMILES CCCC\N=C1/SC[C@@H]2[C@H](O)[C@H](O)[C@@H](O)CN12 Show InChI InChI=1S/C11H20N2O3S/c1-2-3-4-12-11-13-5-8(14)10(16)9(15)7(13)6-17-11/h7-10,14-16H,2-6H2,1H3/b12-11-/t7-,8+,9+,10-/m1/s1 | PDB
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| PDB
Article
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| 5.33E+4 | -25.4 | n/a | n/a | n/a | n/a | n/a | 4.5 | 37 |
The University of Tokyo
| Assay Description
β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl... |
J Biol Chem 289: 14560-8 (2014)
Article DOI: 10.1074/jbc.M113.529529
BindingDB Entry DOI: 10.7270/Q2WH2NW4 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
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