Compile Data Set for Download or QSAR

Found 291 hits with Last Name = 'ashworth' and Initial = 'kl'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50210272 (6-((4-methylpiperazin-1-yl)methyl)-3-(5-(3-phenoxy...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3csc(c3)C#CCOc3ccccc3)c2)CC1 Show InChI InChI=1S/C29H28N4OS/c1-32-11-13-33(14-12-32)19-21-9-10-26-22(16-21)18-27-28(30-31-29(26)27)23-17-25(35-20-23)8-5-15-34-24-6-3-2-4-7-24/h2-4,6-7,9-10,16-17,20H,11-15,18-19H2,1H3,(H,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of Flt1				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50210309 (4-methyl-1-((3-(5-(3-phenoxyprop-1-ynyl)thiophen-3...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3csc(c3)C#CCOc3ccccc3)c2)C(=O)C1 Show InChI InChI=1S/C29H26N4O2S/c1-32-11-12-33(27(34)18-32)17-20-9-10-25-21(14-20)16-26-28(30-31-29(25)26)22-15-24(36-19-22)8-5-13-35-23-6-3-2-4-7-23/h2-4,6-7,9-10,14-15,19H,11-13,16-18H2,1H3,(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blot				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50210271 (7-((1H-1,2,4-triazol-1-yl)methyl)-3-(5-(3-(2-metho...) Show SMILES COCCOCC#Cc1cc(cs1)-c1[nH]nc-2c1Cc1ccc(Cn3cncn3)cc-21 Show InChI InChI=1S/C23H21N5O2S/c1-29-7-8-30-6-2-3-19-10-18(13-31-19)22-21-11-17-5-4-16(12-28-15-24-14-25-28)9-20(17)23(21)27-26-22/h4-5,9-10,13-15H,6-8,11-12H2,1H3,(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of Flt1				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50210271 (7-((1H-1,2,4-triazol-1-yl)methyl)-3-(5-(3-(2-metho...) Show SMILES COCCOCC#Cc1cc(cs1)-c1[nH]nc-2c1Cc1ccc(Cn3cncn3)cc-21 Show InChI InChI=1S/C23H21N5O2S/c1-29-7-8-30-6-2-3-19-10-18(13-31-19)22-21-11-17-5-4-16(12-28-15-24-14-25-28)9-20(17)23(21)27-26-22/h4-5,9-10,13-15H,6-8,11-12H2,1H3,(H,26,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of Flt3				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM50210272 (6-((4-methylpiperazin-1-yl)methyl)-3-(5-(3-phenoxy...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3csc(c3)C#CCOc3ccccc3)c2)CC1 Show InChI InChI=1S/C29H28N4OS/c1-32-11-13-33(14-12-32)19-21-9-10-26-22(16-21)18-27-28(30-31-29(26)27)23-17-25(35-20-23)8-5-15-34-24-6-3-2-4-7-24/h2-4,6-7,9-10,16-17,20H,11-15,18-19H2,1H3,(H,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of Flt4				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50210300 (CHEMBL225311 | N-(3-(4-(6-((4-methylpiperazin-1-yl...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3csc(c3)C#CCNC(=O)c3ccccc3)c2)CC1 Show InChI InChI=1S/C30H29N5OS/c1-34-12-14-35(15-13-34)19-21-9-10-26-23(16-21)18-27-28(32-33-29(26)27)24-17-25(37-20-24)8-5-11-31-30(36)22-6-3-2-4-7-22/h2-4,6-7,9-10,16-17,20H,11-15,18-19H2,1H3,(H,31,36)(H,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blot				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM50210271 (7-((1H-1,2,4-triazol-1-yl)methyl)-3-(5-(3-(2-metho...) Show SMILES COCCOCC#Cc1cc(cs1)-c1[nH]nc-2c1Cc1ccc(Cn3cncn3)cc-21 Show InChI InChI=1S/C23H21N5O2S/c1-29-7-8-30-6-2-3-19-10-18(13-31-19)22-21-11-17-5-4-16(12-28-15-24-14-25-28)9-20(17)23(21)27-26-22/h4-5,9-10,13-15H,6-8,11-12H2,1H3,(H,26,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of Flt4				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50210300 (CHEMBL225311 | N-(3-(4-(6-((4-methylpiperazin-1-yl...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3csc(c3)C#CCNC(=O)c3ccccc3)c2)CC1 Show InChI InChI=1S/C30H29N5OS/c1-34-12-14-35(15-13-34)19-21-9-10-26-23(16-21)18-27-28(32-33-29(26)27)24-17-25(37-20-24)8-5-11-31-30(36)22-6-3-2-4-7-22/h2-4,6-7,9-10,16-17,20H,11-15,18-19H2,1H3,(H,31,36)(H,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by ELISA				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50210299 (6-(2-(4-methylpiperazin-1-yl)ethyl)-3-(5-(3-phenox...) Show SMILES CN1CCN(CCc2ccc-3c(Cc4c-3n[nH]c4-c3csc(c3)C#CCOc3ccccc3)c2)CC1 Show InChI InChI=1S/C30H30N4OS/c1-33-13-15-34(16-14-33)12-11-22-9-10-27-23(18-22)20-28-29(31-32-30(27)28)24-19-26(36-21-24)8-5-17-35-25-6-3-2-4-7-25/h2-4,6-7,9-10,18-19,21H,11-17,20H2,1H3,(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blot				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50210271 (7-((1H-1,2,4-triazol-1-yl)methyl)-3-(5-(3-(2-metho...) Show SMILES COCCOCC#Cc1cc(cs1)-c1[nH]nc-2c1Cc1ccc(Cn3cncn3)cc-21 Show InChI InChI=1S/C23H21N5O2S/c1-29-7-8-30-6-2-3-19-10-18(13-31-19)22-21-11-17-5-4-16(12-28-15-24-14-25-28)9-20(17)23(21)27-26-22/h4-5,9-10,13-15H,6-8,11-12H2,1H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blot				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50210272 (6-((4-methylpiperazin-1-yl)methyl)-3-(5-(3-phenoxy...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3csc(c3)C#CCOc3ccccc3)c2)CC1 Show InChI InChI=1S/C29H28N4OS/c1-32-11-13-33(14-12-32)19-21-9-10-26-22(16-21)18-27-28(30-31-29(26)27)23-17-25(35-20-23)8-5-15-34-24-6-3-2-4-7-24/h2-4,6-7,9-10,16-17,20H,11-15,18-19H2,1H3,(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blot				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50210309 (4-methyl-1-((3-(5-(3-phenoxyprop-1-ynyl)thiophen-3...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3csc(c3)C#CCOc3ccccc3)c2)C(=O)C1 Show InChI InChI=1S/C29H26N4O2S/c1-32-11-12-33(27(34)18-32)17-20-9-10-25-21(14-20)16-26-28(30-31-29(25)26)22-15-24(36-19-22)8-5-13-35-23-6-3-2-4-7-23/h2-4,6-7,9-10,14-15,19H,11-13,16-18H2,1H3,(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human KDR kinase by HTRF assay				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50210277 (3-(5-(3-methoxyprop-1-ynyl)thiophen-3-yl)-6-((4-me...) Show SMILES COCC#Cc1cc(cs1)-c1[nH]nc-2c1Cc1cc(CN3CCN(C)CC3)ccc-21 Show InChI InChI=1S/C24H26N4OS/c1-27-7-9-28(10-8-27)15-17-5-6-21-18(12-17)14-22-23(25-26-24(21)22)19-13-20(30-16-19)4-3-11-29-2/h5-6,12-13,16H,7-11,14-15H2,1-2H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blot				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM50210272 (6-((4-methylpiperazin-1-yl)methyl)-3-(5-(3-phenoxy...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3csc(c3)C#CCOc3ccccc3)c2)CC1 Show InChI InChI=1S/C29H28N4OS/c1-32-11-13-33(14-12-32)19-21-9-10-26-22(16-21)18-27-28(30-31-29(26)27)23-17-25(35-20-23)8-5-15-34-24-6-3-2-4-7-24/h2-4,6-7,9-10,16-17,20H,11-15,18-19H2,1H3,(H,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of CSF1R				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50210269 (4-(4-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihyd...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3csc(c3)C#CCCO)c2)CC1 Show InChI InChI=1S/C24H26N4OS/c1-27-7-9-28(10-8-27)15-17-5-6-21-18(12-17)14-22-23(25-26-24(21)22)19-13-20(30-16-19)4-2-3-11-29/h5-6,12-13,16,29H,3,7-11,14-15H2,1H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blot				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50210293 (4-((3-(5-(3-phenoxyprop-1-ynyl)thiophen-3-yl)-1,4-...) Show SMILES NC(=O)N1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3csc(c3)C#CCOc3ccccc3)c2)CC1 Show InChI InChI=1S/C29H27N5O2S/c30-29(35)34-12-10-33(11-13-34)18-20-8-9-25-21(15-20)17-26-27(31-32-28(25)26)22-16-24(37-19-22)7-4-14-36-23-5-2-1-3-6-23/h1-3,5-6,8-9,15-16,19H,10-14,17-18H2,(H2,30,35)(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human KDR kinase by HTRF assay				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM50210271 (7-((1H-1,2,4-triazol-1-yl)methyl)-3-(5-(3-(2-metho...) Show SMILES COCCOCC#Cc1cc(cs1)-c1[nH]nc-2c1Cc1ccc(Cn3cncn3)cc-21 Show InChI InChI=1S/C23H21N5O2S/c1-29-7-8-30-6-2-3-19-10-18(13-31-19)22-21-11-17-5-4-16(12-28-15-24-14-25-28)9-20(17)23(21)27-26-22/h4-5,9-10,13-15H,6-8,11-12H2,1H3,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of CSF1R				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50210272 (6-((4-methylpiperazin-1-yl)methyl)-3-(5-(3-phenoxy...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3csc(c3)C#CCOc3ccccc3)c2)CC1 Show InChI InChI=1S/C29H28N4OS/c1-32-11-13-33(14-12-32)19-21-9-10-26-22(16-21)18-27-28(30-31-29(26)27)23-17-25(35-20-23)8-5-15-34-24-6-3-2-4-7-24/h2-4,6-7,9-10,16-17,20H,11-15,18-19H2,1H3,(H,30,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of Flt3				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50210316 (3-((3-(5-(3-phenoxyprop-1-ynyl)thiophen-3-yl)-1,4-...) Show SMILES C(Oc1ccccc1)C#Cc1cc(cs1)-c1[nH]nc-2c1Cc1cc(CN3CCSC3)ccc-21 Show InChI InChI=1S/C27H23N3OS2/c1-2-5-22(6-3-1)31-11-4-7-23-14-21(17-33-23)26-25-15-20-13-19(16-30-10-12-32-18-30)8-9-24(20)27(25)29-28-26/h1-3,5-6,8-9,13-14,17H,10-12,15-16,18H2,(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blot				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50210284 (CHEMBL374690 | N,N-dimethyl-2-(3-(5-(3-phenoxyprop...) Show SMILES CN(C)C(=O)COc1ccc-2c(Cc3c-2n[nH]c3-c2csc(c2)C#CCOc2ccccc2)c1 Show InChI InChI=1S/C27H23N3O3S/c1-30(2)25(31)16-33-21-10-11-23-18(13-21)15-24-26(28-29-27(23)24)19-14-22(34-17-19)9-6-12-32-20-7-4-3-5-8-20/h3-5,7-8,10-11,13-14,17H,12,15-16H2,1-2H3,(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blot				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50210306 (6-(4-methylpiperazin-1-yl)-3-(5-(3-phenoxyprop-1-y...) Show SMILES CN1CCN(CC1)c1ccc-2c(Cc3c-2n[nH]c3-c2csc(c2)C#CCOc2ccccc2)c1 Show InChI InChI=1S/C28H26N4OS/c1-31-11-13-32(14-12-31)22-9-10-25-20(16-22)18-26-27(29-30-28(25)26)21-17-24(34-19-21)8-5-15-33-23-6-3-2-4-7-23/h2-4,6-7,9-10,16-17,19H,11-15,18H2,1H3,(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blot				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50210296 (3-(5-(3-(2-methoxyethoxy)prop-1-ynyl)thiophen-3-yl...) Show SMILES COCCOCC#Cc1cc(cs1)-c1[nH]nc2-c3ccc(CN4CCN(C)CC4)cc3C(=O)c12 Show InChI InChI=1S/C26H28N4O3S/c1-29-7-9-30(10-8-29)16-18-5-6-21-22(14-18)26(31)23-24(27-28-25(21)23)19-15-20(34-17-19)4-3-11-33-13-12-32-2/h5-6,14-15,17H,7-13,16H2,1-2H3,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blot				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50210305 (1-(3-(4-(6-((4-methylpiperazin-1-yl)methyl)-1,4-di...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3csc(c3)C#CCNC(=O)Nc3ccccc3)c2)CC1 Show InChI InChI=1S/C30H30N6OS/c1-35-12-14-36(15-13-35)19-21-9-10-26-22(16-21)18-27-28(33-34-29(26)27)23-17-25(38-20-23)8-5-11-31-30(37)32-24-6-3-2-4-7-24/h2-4,6-7,9-10,16-17,20H,11-15,18-19H2,1H3,(H,33,34)(H2,31,32,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human KDR kinase by HTRF assay				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50210285 (1-methyl-4-((3-(5-(3-phenoxyprop-1-ynyl)thiophen-3...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3csc(c3)C#CCOc3ccccc3)c2)CC1=O Show InChI InChI=1S/C29H26N4O2S/c1-32-11-12-33(18-27(32)34)17-20-9-10-25-21(14-20)16-26-28(30-31-29(25)26)22-15-24(36-19-22)8-5-13-35-23-6-3-2-4-7-23/h2-4,6-7,9-10,14-15,19H,11-13,16-18H2,1H3,(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human KDR kinase by HTRF assay				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50210314 (6-((1-methylpiperidin-4-yl)methyl)-3-(5-(3-phenoxy...) Show SMILES CN1CCC(Cc2ccc-3c(Cc4c-3n[nH]c4-c3csc(c3)C#CCOc3ccccc3)c2)CC1 Show InChI InChI=1S/C30H29N3OS/c1-33-13-11-21(12-14-33)16-22-9-10-27-23(17-22)19-28-29(31-32-30(27)28)24-18-26(35-20-24)8-5-15-34-25-6-3-2-4-7-25/h2-4,6-7,9-10,17-18,20-21H,11-16,19H2,1H3,(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human KDR kinase by HTRF assay				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188749 (1-methyl-1-((5-(7-((4-methylpiperazin-1-yl)methyl)...) Show SMILES CN(Cc1ccc(s1)-c1[nH]nc-2c1Cc1ccc(CN3CCN(C)CC3)cc-21)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C30H31F3N6OS/c1-37-10-12-39(13-11-37)17-19-6-7-20-15-25-27(24(20)14-19)35-36-28(25)26-9-8-23(41-26)18-38(2)29(40)34-22-5-3-4-21(16-22)30(31,32)33/h3-9,14,16H,10-13,15,17-18H2,1-2H3,(H,34,40)(H,35,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR at 1 mM ATP by HTRF assay				Bioorg Med Chem Lett 16: 4266-71 (2006) Article DOI: 10.1016/j.bmcl.2006.05.066 BindingDB Entry DOI: 10.7270/Q2NP242Q
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50210306 (6-(4-methylpiperazin-1-yl)-3-(5-(3-phenoxyprop-1-y...) Show SMILES CN1CCN(CC1)c1ccc-2c(Cc3c-2n[nH]c3-c2csc(c2)C#CCOc2ccccc2)c1 Show InChI InChI=1S/C28H26N4OS/c1-31-11-13-32(14-12-31)22-9-10-25-20(16-22)18-26-27(29-30-28(25)26)21-17-24(34-19-21)8-5-15-33-23-6-3-2-4-7-23/h2-4,6-7,9-10,16-17,19H,11-15,18H2,1H3,(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blot				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188753 (3-(3-chlorophenyl)-1-methyl-1-((5-(7-((4-methylpip...) Show SMILES CN(Cc1ccc(s1)-c1[nH]nc-2c1Cc1ccc(CN3CCN(C)CC3)cc-21)C(=O)Nc1cccc(Cl)c1 Show InChI InChI=1S/C29H31ClN6OS/c1-34-10-12-36(13-11-34)17-19-6-7-20-15-25-27(24(20)14-19)32-33-28(25)26-9-8-23(38-26)18-35(2)29(37)31-22-5-3-4-21(30)16-22/h3-9,14,16H,10-13,15,17-18H2,1-2H3,(H,31,37)(H,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR at 1 mM ATP by HTRF assay				Bioorg Med Chem Lett 16: 4266-71 (2006) Article DOI: 10.1016/j.bmcl.2006.05.066 BindingDB Entry DOI: 10.7270/Q2NP242Q
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50210271 (7-((1H-1,2,4-triazol-1-yl)methyl)-3-(5-(3-(2-metho...) Show SMILES COCCOCC#Cc1cc(cs1)-c1[nH]nc-2c1Cc1ccc(Cn3cncn3)cc-21 Show InChI InChI=1S/C23H21N5O2S/c1-29-7-8-30-6-2-3-19-10-18(13-31-19)22-21-11-17-5-4-16(12-28-15-24-14-25-28)9-20(17)23(21)27-26-22/h4-5,9-10,13-15H,6-8,11-12H2,1H3,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of c-Kit				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50210296 (3-(5-(3-(2-methoxyethoxy)prop-1-ynyl)thiophen-3-yl...) Show SMILES COCCOCC#Cc1cc(cs1)-c1[nH]nc2-c3ccc(CN4CCN(C)CC4)cc3C(=O)c12 Show InChI InChI=1S/C26H28N4O3S/c1-29-7-9-30(10-8-29)16-18-5-6-21-22(14-18)26(31)23-24(27-28-25(21)23)19-15-20(34-17-19)4-3-11-33-13-12-32-2/h5-6,14-15,17H,7-13,16H2,1-2H3,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human KDR				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50188731 (1-((5-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihy...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3ccc(CNC(=O)Nc4ccc(cc4)C(F)(F)F)s3)c2)CC1 Show InChI InChI=1S/C29H29F3N6OS/c1-37-10-12-38(13-11-37)17-18-2-8-23-19(14-18)15-24-26(23)35-36-27(24)25-9-7-22(40-25)16-33-28(39)34-21-5-3-20(4-6-21)29(30,31)32/h2-9,14H,10-13,15-17H2,1H3,(H,35,36)(H2,33,34,39)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of cKit at 1 mM ATP by HTRF assay				Bioorg Med Chem Lett 16: 4266-71 (2006) Article DOI: 10.1016/j.bmcl.2006.05.066 BindingDB Entry DOI: 10.7270/Q2NP242Q
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50210303 (6-((1H-1,2,4-triazol-1-yl)methyl)-3-(5-(3-(2-metho...) Show SMILES COCCOCC#Cc1cc(cs1)-c1[nH]nc-2c1Cc1cc(Cn3cncn3)ccc-21 Show InChI InChI=1S/C23H21N5O2S/c1-29-7-8-30-6-2-3-19-10-18(13-31-19)22-21-11-17-9-16(12-28-15-24-14-25-28)4-5-20(17)23(21)27-26-22/h4-5,9-10,13-15H,6-8,11-12H2,1H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blot				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50188749 (1-methyl-1-((5-(7-((4-methylpiperazin-1-yl)methyl)...) Show SMILES CN(Cc1ccc(s1)-c1[nH]nc-2c1Cc1ccc(CN3CCN(C)CC3)cc-21)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C30H31F3N6OS/c1-37-10-12-39(13-11-37)17-19-6-7-20-15-25-27(24(20)14-19)35-36-28(25)26-9-8-23(41-26)18-38(2)29(40)34-22-5-3-4-21(16-22)30(31,32)33/h3-9,14,16H,10-13,15,17-18H2,1-2H3,(H,34,40)(H,35,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of FLT1 at 1mM ATP by HTRF assay				Bioorg Med Chem Lett 16: 4266-71 (2006) Article DOI: 10.1016/j.bmcl.2006.05.066 BindingDB Entry DOI: 10.7270/Q2NP242Q
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50210289 (6-((1H-1,2,4-triazol-1-yl)methyl)-3-(5-(3-phenoxyp...) Show SMILES C(Oc1ccccc1)C#Cc1cc(cs1)-c1[nH]nc-2c1Cc1cc(Cn3cncn3)ccc-21 Show InChI InChI=1S/C26H19N5OS/c1-2-5-21(6-3-1)32-10-4-7-22-12-20(15-33-22)25-24-13-19-11-18(14-31-17-27-16-28-31)8-9-23(19)26(24)30-29-25/h1-3,5-6,8-9,11-12,15-17H,10,13-14H2,(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blot				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50210305 (1-(3-(4-(6-((4-methylpiperazin-1-yl)methyl)-1,4-di...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3csc(c3)C#CCNC(=O)Nc3ccccc3)c2)CC1 Show InChI InChI=1S/C30H30N6OS/c1-35-12-14-36(15-13-35)19-21-9-10-26-22(16-21)18-27-28(33-34-29(26)27)23-17-25(38-20-23)8-5-11-31-30(37)32-24-6-3-2-4-7-24/h2-4,6-7,9-10,16-17,20H,11-15,18-19H2,1H3,(H,33,34)(H2,31,32,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by ELISA				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50210271 (7-((1H-1,2,4-triazol-1-yl)methyl)-3-(5-(3-(2-metho...) Show SMILES COCCOCC#Cc1cc(cs1)-c1[nH]nc-2c1Cc1ccc(Cn3cncn3)cc-21 Show InChI InChI=1S/C23H21N5O2S/c1-29-7-8-30-6-2-3-19-10-18(13-31-19)22-21-11-17-5-4-16(12-28-15-24-14-25-28)9-20(17)23(21)27-26-22/h4-5,9-10,13-15H,6-8,11-12H2,1H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by ELISA				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188764 (3-(4-fluorophenyl)-1-methyl-1-((5-(7-((4-methylpip...) Show SMILES CN(Cc1ccc(s1)-c1[nH]nc-2c1Cc1ccc(CN3CCN(C)CC3)cc-21)C(=O)Nc1ccc(F)cc1 Show InChI InChI=1S/C29H31FN6OS/c1-34-11-13-36(14-12-34)17-19-3-4-20-16-25-27(24(20)15-19)32-33-28(25)26-10-9-23(38-26)18-35(2)29(37)31-22-7-5-21(30)6-8-22/h3-10,15H,11-14,16-18H2,1-2H3,(H,31,37)(H,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR at 1 mM ATP by HTRF assay				Bioorg Med Chem Lett 16: 4266-71 (2006) Article DOI: 10.1016/j.bmcl.2006.05.066 BindingDB Entry DOI: 10.7270/Q2NP242Q
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50188754 (3-(4-bromophenyl)-1-methyl-1-((5-(7-((4-methylpipe...) Show SMILES CN(Cc1ccc(s1)-c1[nH]nc-2c1Cc1ccc(CN3CCN(C)CC3)cc-21)C(=O)Nc1ccc(Br)cc1 Show InChI InChI=1S/C29H31BrN6OS/c1-34-11-13-36(14-12-34)17-19-3-4-20-16-25-27(24(20)15-19)32-33-28(25)26-10-9-23(38-26)18-35(2)29(37)31-22-7-5-21(30)6-8-22/h3-10,15H,11-14,16-18H2,1-2H3,(H,31,37)(H,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of cKit at 1 mM ATP by HTRF assay				Bioorg Med Chem Lett 16: 4266-71 (2006) Article DOI: 10.1016/j.bmcl.2006.05.066 BindingDB Entry DOI: 10.7270/Q2NP242Q
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50188748 (1-((5-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihy...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3ccc(CNC(=O)Nc4cccc(c4)C(F)(F)F)s3)c2)CC1 Show InChI InChI=1S/C29H29F3N6OS/c1-37-9-11-38(12-10-37)17-18-5-7-23-19(13-18)14-24-26(23)35-36-27(24)25-8-6-22(40-25)16-33-28(39)34-21-4-2-3-20(15-21)29(30,31)32/h2-8,13,15H,9-12,14,16-17H2,1H3,(H,35,36)(H2,33,34,39)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of cKit at 1 mM ATP by HTRF assay				Bioorg Med Chem Lett 16: 4266-71 (2006) Article DOI: 10.1016/j.bmcl.2006.05.066 BindingDB Entry DOI: 10.7270/Q2NP242Q
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188759 (1-methyl-1-((5-(7-((4-methylpiperazin-1-yl)methyl)...) Show SMILES CN(Cc1ccc(s1)-c1[nH]nc-2c1Cc1ccc(CN3CCN(C)CC3)cc-21)C(=O)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C30H31F3N6O2S/c1-37-11-13-39(14-12-37)17-19-3-4-20-16-25-27(24(20)15-19)35-36-28(25)26-10-9-23(42-26)18-38(2)29(40)34-21-5-7-22(8-6-21)41-30(31,32)33/h3-10,15H,11-14,16-18H2,1-2H3,(H,34,40)(H,35,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR at 1 mM ATP by HTRF assay				Bioorg Med Chem Lett 16: 4266-71 (2006) Article DOI: 10.1016/j.bmcl.2006.05.066 BindingDB Entry DOI: 10.7270/Q2NP242Q
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50188749 (1-methyl-1-((5-(7-((4-methylpiperazin-1-yl)methyl)...) Show SMILES CN(Cc1ccc(s1)-c1[nH]nc-2c1Cc1ccc(CN3CCN(C)CC3)cc-21)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C30H31F3N6OS/c1-37-10-12-39(13-11-37)17-19-6-7-20-15-25-27(24(20)14-19)35-36-28(25)26-9-8-23(41-26)18-38(2)29(40)34-22-5-3-4-21(16-22)30(31,32)33/h3-9,14,16H,10-13,15,17-18H2,1-2H3,(H,34,40)(H,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of cKit at 1 mM ATP by HTRF assay				Bioorg Med Chem Lett 16: 4266-71 (2006) Article DOI: 10.1016/j.bmcl.2006.05.066 BindingDB Entry DOI: 10.7270/Q2NP242Q
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188769 (3-(3,4-dichlorophenyl)-1-methyl-1-((5-(7-((4-methy...) Show SMILES CN(Cc1ccc(s1)-c1[nH]nc-2c1Cc1ccc(CN3CCN(C)CC3)cc-21)C(=O)Nc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C29H30Cl2N6OS/c1-35-9-11-37(12-10-35)16-18-3-4-19-14-23-27(22(19)13-18)33-34-28(23)26-8-6-21(39-26)17-36(2)29(38)32-20-5-7-24(30)25(31)15-20/h3-8,13,15H,9-12,14,16-17H2,1-2H3,(H,32,38)(H,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR at 1 mM ATP by HTRF assay				Bioorg Med Chem Lett 16: 4266-71 (2006) Article DOI: 10.1016/j.bmcl.2006.05.066 BindingDB Entry DOI: 10.7270/Q2NP242Q
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50210285 (1-methyl-4-((3-(5-(3-phenoxyprop-1-ynyl)thiophen-3...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3csc(c3)C#CCOc3ccccc3)c2)CC1=O Show InChI InChI=1S/C29H26N4O2S/c1-32-11-12-33(18-27(32)34)17-20-9-10-25-21(14-20)16-26-28(30-31-29(25)26)22-15-24(36-19-22)8-5-13-35-23-6-3-2-4-7-23/h2-4,6-7,9-10,14-15,19H,11-13,16-18H2,1H3,(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blot				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50188727 (1-methyl-1-((5-(6-((4-methylpiperazin-1-yl)methyl)...) Show SMILES CN(Cc1ccc(s1)-c1[nH]nc-2c1Cc1cc(CN3CCN(C)CC3)ccc-21)C(=O)Nc1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C30H31F3N6O2S/c1-37-10-12-39(13-11-37)17-19-6-8-24-20(14-19)15-25-27(24)35-36-28(25)26-9-7-23(42-26)18-38(2)29(40)34-21-4-3-5-22(16-21)41-30(31,32)33/h3-9,14,16H,10-13,15,17-18H2,1-2H3,(H,34,40)(H,35,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of FLT1 at 1mM ATP by HTRF assay				Bioorg Med Chem Lett 16: 4266-71 (2006) Article DOI: 10.1016/j.bmcl.2006.05.066 BindingDB Entry DOI: 10.7270/Q2NP242Q
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50188759 (1-methyl-1-((5-(7-((4-methylpiperazin-1-yl)methyl)...) Show SMILES CN(Cc1ccc(s1)-c1[nH]nc-2c1Cc1ccc(CN3CCN(C)CC3)cc-21)C(=O)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C30H31F3N6O2S/c1-37-11-13-39(14-12-37)17-19-3-4-20-16-25-27(24(20)15-19)35-36-28(25)26-10-9-23(42-26)18-38(2)29(40)34-21-5-7-22(8-6-21)41-30(31,32)33/h3-10,15H,11-14,16-18H2,1-2H3,(H,34,40)(H,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of cKit at 1 mM ATP by HTRF assay				Bioorg Med Chem Lett 16: 4266-71 (2006) Article DOI: 10.1016/j.bmcl.2006.05.066 BindingDB Entry DOI: 10.7270/Q2NP242Q
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188754 (3-(4-bromophenyl)-1-methyl-1-((5-(7-((4-methylpipe...) Show SMILES CN(Cc1ccc(s1)-c1[nH]nc-2c1Cc1ccc(CN3CCN(C)CC3)cc-21)C(=O)Nc1ccc(Br)cc1 Show InChI InChI=1S/C29H31BrN6OS/c1-34-11-13-36(14-12-34)17-19-3-4-20-16-25-27(24(20)15-19)32-33-28(25)26-10-9-23(38-26)18-35(2)29(37)31-22-7-5-21(30)6-8-22/h3-10,15H,11-14,16-18H2,1-2H3,(H,31,37)(H,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR at 1 mM ATP by HTRF assay				Bioorg Med Chem Lett 16: 4266-71 (2006) Article DOI: 10.1016/j.bmcl.2006.05.066 BindingDB Entry DOI: 10.7270/Q2NP242Q
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50188753 (3-(3-chlorophenyl)-1-methyl-1-((5-(7-((4-methylpip...) Show SMILES CN(Cc1ccc(s1)-c1[nH]nc-2c1Cc1ccc(CN3CCN(C)CC3)cc-21)C(=O)Nc1cccc(Cl)c1 Show InChI InChI=1S/C29H31ClN6OS/c1-34-10-12-36(13-11-34)17-19-6-7-20-15-25-27(24(20)14-19)32-33-28(25)26-9-8-23(38-26)18-35(2)29(37)31-22-5-3-4-21(30)16-22/h3-9,14,16H,10-13,15,17-18H2,1-2H3,(H,31,37)(H,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of FLT1 at 1mM ATP by HTRF assay				Bioorg Med Chem Lett 16: 4266-71 (2006) Article DOI: 10.1016/j.bmcl.2006.05.066 BindingDB Entry DOI: 10.7270/Q2NP242Q
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188736 (3-(3-fluoro-5-(trifluoromethyl)phenyl)-1-methyl-1-...) Show SMILES CN(Cc1ccc(s1)-c1[nH]nc-2c1Cc1cc(CN3CCN(C)CC3)ccc-21)C(=O)Nc1cc(F)cc(c1)C(F)(F)F Show InChI InChI=1S/C30H30F4N6OS/c1-38-7-9-40(10-8-38)16-18-3-5-24-19(11-18)12-25-27(24)36-37-28(25)26-6-4-23(42-26)17-39(2)29(41)35-22-14-20(30(32,33)34)13-21(31)15-22/h3-6,11,13-15H,7-10,12,16-17H2,1-2H3,(H,35,41)(H,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR at 1 mM ATP by HTRF assay				Bioorg Med Chem Lett 16: 4266-71 (2006) Article DOI: 10.1016/j.bmcl.2006.05.066 BindingDB Entry DOI: 10.7270/Q2NP242Q
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50210301 (6-((1H-pyrazol-1-yl)methyl)-3-(5-(3-phenoxyprop-1-...) Show SMILES C(Oc1ccccc1)C#Cc1cc(cs1)-c1[nH]nc-2c1Cc1cc(Cn3cccn3)ccc-21 Show InChI InChI=1S/C27H20N4OS/c1-2-6-22(7-3-1)32-13-4-8-23-15-21(18-33-23)26-25-16-20-14-19(17-31-12-5-11-28-31)9-10-24(20)27(25)30-29-26/h1-3,5-7,9-12,14-15,18H,13,16-17H2,(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blot				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50210293 (4-((3-(5-(3-phenoxyprop-1-ynyl)thiophen-3-yl)-1,4-...) Show SMILES NC(=O)N1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3csc(c3)C#CCOc3ccccc3)c2)CC1 Show InChI InChI=1S/C29H27N5O2S/c30-29(35)34-12-10-33(11-13-34)18-20-8-9-25-21(15-20)17-26-27(31-32-28(25)26)22-16-24(37-19-22)7-4-14-36-23-5-2-1-3-6-23/h1-3,5-6,8-9,15-16,19H,10-14,17-18H2,(H2,30,35)(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blot				J Med Chem 50: 2011-29 (2007) Article DOI: 10.1021/jm061223o BindingDB Entry DOI: 10.7270/Q2TB16K0
					More data for this Ligand-Target Pair

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