BindingDB PrimarySearch

Found 97 hits with Last Name = 'begum' and Initial = 'a'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cytochrome P450 1A2 (Homo sapiens (Human))	BDBM50582304 (CHEMBL5072213) Show SMILES OCCNC(=O)c1cccn2c1nc1c3ccccc3ccc1c2=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human hepatic CYP1A2 expressed in baculovirus insect cell expression system in presence of CEC substrate measured by fluore...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50582301 (CHEMBL5091256) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50019315 (CHEMBL3289420) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
Cytochrome P450 1A2 (Homo sapiens (Human))	BDBM50582293 (CHEMBL5075517) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human hepatic CYP1A2 expressed in baculovirus insect cell expression system in presence of CEC substrate measured by fluore...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50582305 (CHEMBL5091818) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
Cytochrome P450 1A2 (Homo sapiens (Human))	BDBM50582302 (CHEMBL5072152) Show SMILES CNCCNC(=O)c1cccn2c1nc1c3ccccc3ccc1c2=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human hepatic CYP1A2 expressed in baculovirus insect cell expression system in presence of CEC substrate measured by fluore...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50019324 (CHEMBL3289398) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50019316 (CHEMBL3289421) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50582313 (CHEMBL5093823) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50582302 (CHEMBL5072152) Show SMILES CNCCNC(=O)c1cccn2c1nc1c3ccccc3ccc1c2=O Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
Cytochrome P450 1A2 (Homo sapiens (Human))	BDBM50582300 (CHEMBL5074659) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human hepatic CYP1A2 expressed in baculovirus insect cell expression system in presence of CEC substrate measured by fluore...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50582314 (CHEMBL5076121) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50582333 (CHEMBL5088110) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50582320 (CHEMBL5089364) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50582300 (CHEMBL5074659) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50582299 (CHEMBL5091051) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50582330 (CHEMBL5094886) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50582319 (CHEMBL5082214) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50582334 (CHEMBL5093028) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50582321 (CHEMBL5090345) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50582332 (CHEMBL5080399) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	920	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50582328 (CHEMBL5080842) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	990	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50582331 (CHEMBL5071620) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50582316 (CHEMBL5077311) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50582312 (CHEMBL5084657) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50582315 (CHEMBL5094505) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
Listeriolysin regulatory protein (Listeria monocytogenes serovar 1/2a (strain ATCC B...)	BDBM50453142 (CHEMBL4216912) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to Listeria monocytogenes 6-His-tagged PrfA expressed in Escherichia coli BL21 (DE3) pLysS assessed as inhibition of protein binding...				J Med Chem 61: 4165-4175 (2018) Article DOI: 10.1021/acs.jmedchem.8b00289 BindingDB Entry DOI: 10.7270/Q2T1566G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50582309 (CHEMBL5091868) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
Listeriolysin regulatory protein (Listeria monocytogenes serovar 1/2a (strain ATCC B...)	BDBM50453145 (CHEMBL4213989) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to Listeria monocytogenes 6-His-tagged PrfA expressed in Escherichia coli BL21 (DE3) pLysS assessed as inhibition of protein binding...				J Med Chem 61: 4165-4175 (2018) Article DOI: 10.1021/acs.jmedchem.8b00289 BindingDB Entry DOI: 10.7270/Q2T1566G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50582296 (CHEMBL5089676) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
Cytochrome P450 1A2 (Homo sapiens (Human))	BDBM50582296 (CHEMBL5089676) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human hepatic CYP1A2 expressed in baculovirus insect cell expression system in presence of CEC substrate measured by fluore...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
Listeriolysin regulatory protein (Listeria monocytogenes serovar 1/2a (strain ATCC B...)	BDBM50453144 (CHEMBL4215787) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to Listeria monocytogenes 6-His-tagged PrfA expressed in Escherichia coli BL21 (DE3) pLysS assessed as inhibition of protein binding...				J Med Chem 61: 4165-4175 (2018) Article DOI: 10.1021/acs.jmedchem.8b00289 BindingDB Entry DOI: 10.7270/Q2T1566G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50582305 (CHEMBL5091818) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition on hERG expressed in HEK293 cells by Qpatch method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50582299 (CHEMBL5091051) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition on hERG expressed in HEK293 cells by Qpatch method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50582300 (CHEMBL5074659) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition on hERG expressed in HEK293 cells by Qpatch method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50582329 (CHEMBL5091418) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50582293 (CHEMBL5075517) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.97E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition on hERG expressed in HEK293 cells by Qpatch method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50582306 (CHEMBL5083095) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50582294 (CHEMBL5092554) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.44E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition on hERG expressed in HEK293 cells by Qpatch method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
Cytochrome P450 1A2 (Homo sapiens (Human))	BDBM50582297 (CHEMBL5082744) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human hepatic CYP1A2 expressed in baculovirus insect cell expression system in presence of CEC substrate measured by fluore...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
Listeriolysin regulatory protein (Listeria monocytogenes serovar 1/2a (strain ATCC B...)	BDBM50453146 (CHEMBL1204537) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to Listeria monocytogenes 6-His-tagged PrfA expressed in Escherichia coli BL21 (DE3) pLysS assessed as inhibition of protein binding...				J Med Chem 61: 4165-4175 (2018) Article DOI: 10.1021/acs.jmedchem.8b00289 BindingDB Entry DOI: 10.7270/Q2T1566G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50582301 (CHEMBL5091256) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition on hERG expressed in HEK293 cells by Qpatch method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50582310 (CHEMBL5088652) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50582295 (CHEMBL5081532) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition on hERG expressed in HEK293 cells by Qpatch method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50582326 (CHEMBL5080196) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50582308 (CHEMBL5089657) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50582311 (CHEMBL5081206) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.86E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM7459 (2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...) Show SMILES Oc1cc(O)c2c(c1)oc(cc2=O)-c1ccc(O)c(O)c1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ume£ University Curated by ChEMBL					Assay Description Binding affinity to TTR in human plasma assessed as protein stabilization preincubated for 1 hr followed by urea-mediated denaturation by Western blo...				J Med Chem 58: 6507-15 (2015) Article DOI: 10.1021/acs.jmedchem.5b00544 BindingDB Entry DOI: 10.7270/Q2P84DP1
Ume£ University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50582292 (CHEMBL5087053) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition on hERG expressed in HEK293 cells by Qpatch method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50582296 (CHEMBL5089676) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition on hERG expressed in HEK293 cells by Qpatch method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair

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