Found 24 hits with Last Name = 'bennett' and Initial = 'mk' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Purine nucleoside phosphorylase
(Homo sapiens (Human)) | BDBM50005795
(2,8-Diamino-9-thiophen-2-ylmethyl-1,9-dihydro-puri...)Show InChI InChI=1S/C10H10N6OS/c11-9-14-7-6(8(17)15-9)13-10(12)16(7)4-5-2-1-3-18-5/h1-3H,4H2,(H2,12,13)(H3,11,14,15,17) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 67 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Ability to inhibit purine nucleoside phosphorylase (PNP) |
J Med Chem 35: 1605-9 (1992)
BindingDB Entry DOI: 10.7270/Q2KW5GPH |
More data for this Ligand-Target Pair | |
Purine nucleoside phosphorylase
(Homo sapiens (Human)) | BDBM50368609
(CHEMBL604660)Show SMILES O[C@@H]1[C@@H](CI)OC([C@@H]1O)c1c[nH]c2c1nc[nH]c2=O |r| Show InChI InChI=1S/C11H12IN3O4/c12-1-5-8(16)9(17)10(19-5)4-2-13-7-6(4)14-3-15-11(7)18/h2-3,5,8-10,13,16-17H,1H2,(H,14,15,18)/t5-,8-,9-,10?/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 176 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Ability to inhibit purine nucleoside phosphorylase (PNP) |
J Med Chem 35: 1605-9 (1992)
BindingDB Entry DOI: 10.7270/Q2KW5GPH |
More data for this Ligand-Target Pair | |
Purine nucleoside phosphorylase
(Homo sapiens (Human)) | BDBM50368611
(CHEMBL604864)Show SMILES O[C@@H]1[C@@H](CCl)OC([C@@H]1O)c1c[nH]c2c1nc[nH]c2=O |r| Show InChI InChI=1S/C11H12ClN3O4/c12-1-5-8(16)9(17)10(19-5)4-2-13-7-6(4)14-3-15-11(7)18/h2-3,5,8-10,13,16-17H,1H2,(H,14,15,18)/t5-,8-,9-,10?/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Ability to inhibit purine nucleoside phosphorylase (PNP) |
J Med Chem 35: 1605-9 (1992)
BindingDB Entry DOI: 10.7270/Q2KW5GPH |
More data for this Ligand-Target Pair | |
Purine nucleoside phosphorylase
(Homo sapiens (Human)) | BDBM50005916
(2,6-diamino-7-(thien-3-ylmethyl)-3,5-dihydro-4H-py...)Show InChI InChI=1S/C11H11N5OS/c12-9-6(3-5-1-2-18-4-5)7-8(14-9)10(17)16-11(13)15-7/h1-2,4,14H,3,12H2,(H3,13,15,16,17) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 830 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Ability to inhibit purine nucleoside phosphorylase (PNP) |
J Med Chem 35: 1605-9 (1992)
BindingDB Entry DOI: 10.7270/Q2KW5GPH |
More data for this Ligand-Target Pair | |
Purine nucleoside phosphorylase
(Homo sapiens (Human)) | BDBM50230691
(CHEMBL3143996)Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)C1=CNC2C1=NC=NC2=O |r,c:17,t:10,15| Show InChI InChI=1S/C11H13N3O5/c15-2-5-8(16)9(17)10(19-5)4-1-12-7-6(4)13-3-14-11(7)18/h1,3,5,7-10,12,15-17H,2H2/t5-,7?,8-,9-,10+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Ability to inhibit purine nucleoside phosphorylase (PNP) |
J Med Chem 35: 1605-9 (1992)
BindingDB Entry DOI: 10.7270/Q2KW5GPH |
More data for this Ligand-Target Pair | |
Purine nucleoside phosphorylase
(Homo sapiens (Human)) | BDBM50230690
(CHEMBL3143997)Show SMILES NC1=NC(=O)C2NC=C([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C2=N1 |r,c:20,t:1,7| Show InChI InChI=1S/C11H14N4O5/c12-11-14-5-3(1-13-6(5)10(19)15-11)9-8(18)7(17)4(2-16)20-9/h1,4,6-9,13,16-18H,2H2,(H2,12,15,19)/t4-,6?,7-,8-,9+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Ability to inhibit purine nucleoside phosphorylase (PNP) |
J Med Chem 35: 1605-9 (1992)
BindingDB Entry DOI: 10.7270/Q2KW5GPH |
More data for this Ligand-Target Pair | |
Proteasome subunit beta type-8
(Homo sapiens (Human)) | BDBM50277781
((2S)-2-[(2S)-2-[(5-ethoxy-1,2-oxazol-3-yl)formamid...)Show SMILES CCOc1cc(no1)C(=O)N[C@@H](COC)C(=O)N[C@@H](COC)C(=O)N[C@@H](Cc1ccccc1)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C26H34N4O9/c1-5-37-21-12-18(30-39-21)23(32)28-20(14-36-4)25(34)29-19(13-35-3)24(33)27-17(22(31)26(2)15-38-26)11-16-9-7-6-8-10-16/h6-10,12,17,19-20H,5,11,13-15H2,1-4H3,(H,27,33)(H,28,32)(H,29,34)/t17-,19-,20-,26+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Proteolix, Inc.
Curated by ChEMBL
| Assay Description Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISA |
J Med Chem 52: 3028-38 (2009)
Article DOI: 10.1021/jm801329v BindingDB Entry DOI: 10.7270/Q2ZW1KS0 |
More data for this Ligand-Target Pair | |
Proteasome subunit beta type-8
(Homo sapiens (Human)) | BDBM50069989
((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxa...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnccn1)B(O)O |r| Show InChI InChI=1S/C19H25BN4O4/c1-13(2)10-17(20(27)28)24-18(25)15(11-14-6-4-3-5-7-14)23-19(26)16-12-21-8-9-22-16/h3-9,12-13,15,17,27-28H,10-11H2,1-2H3,(H,23,26)(H,24,25)/t15-,17-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 8.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Proteolix, Inc.
Curated by ChEMBL
| Assay Description Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISA |
J Med Chem 52: 3028-38 (2009)
Article DOI: 10.1021/jm801329v BindingDB Entry DOI: 10.7270/Q2ZW1KS0 |
More data for this Ligand-Target Pair | |
Proteasome subunit beta type-8
(Homo sapiens (Human)) | BDBM50277889
(CARFILZOMIB | CHEMBL451887)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)CN1CCOCC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C40H57N5O7/c1-27(2)22-32(36(47)40(5)26-52-40)42-39(50)34(24-30-14-10-7-11-15-30)44-38(49)33(23-28(3)4)43-37(48)31(17-16-29-12-8-6-9-13-29)41-35(46)25-45-18-20-51-21-19-45/h6-15,27-28,31-34H,16-26H2,1-5H3,(H,41,46)(H,42,50)(H,43,48)(H,44,49)/t31-,32-,33-,34-,40+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE PC cid PC sid UniChem
Patents
Similars
| DrugBank Article PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Proteolix, Inc.
Curated by ChEMBL
| Assay Description Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISA |
J Med Chem 52: 3028-38 (2009)
Article DOI: 10.1021/jm801329v BindingDB Entry DOI: 10.7270/Q2ZW1KS0 |
More data for this Ligand-Target Pair | |
Proteasome subunit beta type-8
(Homo sapiens (Human)) | BDBM50277779
(CHEMBL484003 | N-((S)-3-methoxy-1-((S)-3-methoxy-1...)Show SMILES COC[C@H](NC(=O)[C@H](COC)NC(=O)c1cc(C)on1)C(=O)N[C@@H](Cc1ccccc1)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C25H32N4O8/c1-15-10-18(29-37-15)22(31)27-20(13-35-4)24(33)28-19(12-34-3)23(32)26-17(21(30)25(2)14-36-25)11-16-8-6-5-7-9-16/h5-10,17,19-20H,11-14H2,1-4H3,(H,26,32)(H,27,31)(H,28,33)/t17-,19-,20-,25+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Proteolix, Inc.
Curated by ChEMBL
| Assay Description Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISA |
J Med Chem 52: 3028-38 (2009)
Article DOI: 10.1021/jm801329v BindingDB Entry DOI: 10.7270/Q2ZW1KS0 |
More data for this Ligand-Target Pair | |
Proteasome subunit beta type-8
(Homo sapiens (Human)) | BDBM50277815
(3-methoxy-N-((S)-3-methoxy-1-((S)-3-methoxy-1-((S)...)Show SMILES COC[C@H](NC(=O)[C@H](COC)NC(=O)c1cc(OC)no1)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C22H34N4O9/c1-12(2)7-13(18(27)22(3)11-34-22)23-19(28)14(9-31-4)24-20(29)15(10-32-5)25-21(30)16-8-17(33-6)26-35-16/h8,12-15H,7,9-11H2,1-6H3,(H,23,28)(H,24,29)(H,25,30)/t13-,14-,15-,22+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Proteolix, Inc.
Curated by ChEMBL
| Assay Description Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISA |
J Med Chem 52: 3028-38 (2009)
Article DOI: 10.1021/jm801329v BindingDB Entry DOI: 10.7270/Q2ZW1KS0 |
More data for this Ligand-Target Pair | |
Proteasome subunit beta type-8
(Homo sapiens (Human)) | BDBM50277816
(3-methoxy-N-((S)-3-methoxy-1-((S)-3-methoxy-1-((S)...)Show SMILES COC[C@H](NC(=O)[C@H](COC)NC(=O)c1cc(OC)no1)C(=O)N[C@@H](Cc1ccccc1)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C25H32N4O9/c1-25(14-37-25)21(30)16(10-15-8-6-5-7-9-15)26-22(31)17(12-34-2)27-23(32)18(13-35-3)28-24(33)19-11-20(36-4)29-38-19/h5-9,11,16-18H,10,12-14H2,1-4H3,(H,26,31)(H,27,32)(H,28,33)/t16-,17-,18-,25+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Proteolix, Inc.
Curated by ChEMBL
| Assay Description Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISA |
J Med Chem 52: 3028-38 (2009)
Article DOI: 10.1021/jm801329v BindingDB Entry DOI: 10.7270/Q2ZW1KS0 |
More data for this Ligand-Target Pair | |
Proteasome subunit beta type-8
(Homo sapiens (Human)) | BDBM50277780
(5-ethoxy-N-((S)-3-methoxy-1-((S)-3-methoxy-1-((S)-...)Show SMILES CCOc1cc(no1)C(=O)N[C@@H](COC)C(=O)N[C@@H](COC)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C23H36N4O9/c1-7-34-18-9-15(27-36-18)20(29)25-17(11-33-6)22(31)26-16(10-32-5)21(30)24-14(8-13(2)3)19(28)23(4)12-35-23/h9,13-14,16-17H,7-8,10-12H2,1-6H3,(H,24,30)(H,25,29)(H,26,31)/t14-,16-,17-,23+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
Proteolix, Inc.
Curated by ChEMBL
| Assay Description Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISA |
J Med Chem 52: 3028-38 (2009)
Article DOI: 10.1021/jm801329v BindingDB Entry DOI: 10.7270/Q2ZW1KS0 |
More data for this Ligand-Target Pair | |
Proteasome subunit beta type-8
(Homo sapiens (Human)) | BDBM50277818
(2-Me-5-thiazole-Ser(OMe)-Ser(OMe)-Phe-ketoepoxide ...)Show SMILES COC[C@H](NC(=O)[C@H](COC)NC(=O)c1cnc(C)o1)C(=O)N[C@@H](Cc1ccccc1)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C25H32N4O8/c1-15-26-11-20(37-15)24(33)29-19(13-35-4)23(32)28-18(12-34-3)22(31)27-17(21(30)25(2)14-36-25)10-16-8-6-5-7-9-16/h5-9,11,17-19H,10,12-14H2,1-4H3,(H,27,31)(H,28,32)(H,29,33)/t17-,18-,19-,25+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 82 | n/a | n/a | n/a | n/a | n/a | n/a |
Proteolix, Inc.
Curated by ChEMBL
| Assay Description Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISA |
J Med Chem 52: 3028-38 (2009)
Article DOI: 10.1021/jm801329v BindingDB Entry DOI: 10.7270/Q2ZW1KS0 |
More data for this Ligand-Target Pair | |
Proteasome subunit beta type-8
(Homo sapiens (Human)) | BDBM50277778
(CHEMBL484002 | N-((S)-3-methoxy-1-((S)-3-methoxy-1...)Show SMILES COC[C@H](NC(=O)[C@H](COC)NC(=O)c1ccon1)C(=O)N[C@@H](Cc1ccccc1)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C24H30N4O8/c1-24(14-35-24)20(29)17(11-15-7-5-4-6-8-15)25-22(31)18(12-33-2)27-23(32)19(13-34-3)26-21(30)16-9-10-36-28-16/h4-10,17-19H,11-14H2,1-3H3,(H,25,31)(H,26,30)(H,27,32)/t17-,18-,19-,24+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a | n/a |
Proteolix, Inc.
Curated by ChEMBL
| Assay Description Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISA |
J Med Chem 52: 3028-38 (2009)
Article DOI: 10.1021/jm801329v BindingDB Entry DOI: 10.7270/Q2ZW1KS0 |
More data for this Ligand-Target Pair | |
Proteasome subunit beta type-8
(Homo sapiens (Human)) | BDBM50277733
((2S)-3-methoxy-2-[(2S)-3-methoxy-2-[(5-methyl-1,2-...)Show SMILES COC[C@H](NC(=O)[C@H](COC)NC(=O)c1cc(C)on1)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C22H34N4O8/c1-12(2)7-14(18(27)22(4)11-33-22)23-20(29)16(9-31-5)25-21(30)17(10-32-6)24-19(28)15-8-13(3)34-26-15/h8,12,14,16-17H,7,9-11H2,1-6H3,(H,23,29)(H,24,28)(H,25,30)/t14-,16-,17-,22+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 238 | n/a | n/a | n/a | n/a | n/a | n/a |
Proteolix, Inc.
Curated by ChEMBL
| Assay Description Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISA |
J Med Chem 52: 3028-38 (2009)
Article DOI: 10.1021/jm801329v BindingDB Entry DOI: 10.7270/Q2ZW1KS0 |
More data for this Ligand-Target Pair | |
Proteasome subunit beta type-8
(Homo sapiens (Human)) | BDBM50277734
(CHEMBL484157 | N-((S)-3-methoxy-1-((S)-3-methoxy-1...)Show SMILES COC[C@H](NC(=O)[C@H](COC)NC(=O)c1ccon1)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C21H32N4O8/c1-12(2)8-14(17(26)21(3)11-32-21)22-19(28)15(9-30-4)24-20(29)16(10-31-5)23-18(27)13-6-7-33-25-13/h6-7,12,14-16H,8-11H2,1-5H3,(H,22,28)(H,23,27)(H,24,29)/t14-,15-,16-,21+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 607 | n/a | n/a | n/a | n/a | n/a | n/a |
Proteolix, Inc.
Curated by ChEMBL
| Assay Description Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISA |
J Med Chem 52: 3028-38 (2009)
Article DOI: 10.1021/jm801329v BindingDB Entry DOI: 10.7270/Q2ZW1KS0 |
More data for this Ligand-Target Pair | |
Proteasome subunit beta type-8
(Homo sapiens (Human)) | BDBM50277817
(CHEMBL483740 | N-((S)-3-methoxy-1-((S)-3-methoxy-1...)Show SMILES COC[C@H](NC(=O)[C@H](COC)NC(=O)c1cnc(C)o1)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C22H34N4O8/c1-12(2)7-14(18(27)22(4)11-33-22)24-19(28)15(9-31-5)25-20(29)16(10-32-6)26-21(30)17-8-23-13(3)34-17/h8,12,14-16H,7,9-11H2,1-6H3,(H,24,28)(H,25,29)(H,26,30)/t14-,15-,16-,22+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 784 | n/a | n/a | n/a | n/a | n/a | n/a |
Proteolix, Inc.
Curated by ChEMBL
| Assay Description Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISA |
J Med Chem 52: 3028-38 (2009)
Article DOI: 10.1021/jm801329v BindingDB Entry DOI: 10.7270/Q2ZW1KS0 |
More data for this Ligand-Target Pair | |
Purine nucleoside phosphorylase
(Homo sapiens (Human)) | BDBM50005916
(2,6-diamino-7-(thien-3-ylmethyl)-3,5-dihydro-4H-py...)Show InChI InChI=1S/C11H11N5OS/c12-9-6(3-5-1-2-18-4-5)7-8(14-9)10(17)16-11(13)15-7/h1-2,4,14H,3,12H2,(H3,13,15,16,17) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Compound was tested for the inhibitory activity against purine nucleoside phosphorylase (PNP) |
J Med Chem 35: 1605-9 (1992)
BindingDB Entry DOI: 10.7270/Q2KW5GPH |
More data for this Ligand-Target Pair | |
Purine nucleoside phosphorylase
(Homo sapiens (Human)) | BDBM50005924
(2,6-Diamino-7-thiophen-2-ylmethyl-3,5-dihydro-pyrr...)Show InChI InChI=1S/C11H11N5OS/c12-9-6(4-5-2-1-3-18-5)7-8(14-9)10(17)16-11(13)15-7/h1-3,14H,4,12H2,(H3,13,15,16,17) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Compound was tested for the inhibitory activity against purine nucleoside phosphorylase (PNP) |
J Med Chem 35: 1605-9 (1992)
BindingDB Entry DOI: 10.7270/Q2KW5GPH |
More data for this Ligand-Target Pair | |
Purine nucleoside phosphorylase
(Homo sapiens (Human)) | BDBM50404028
(CHEMBL2021376)Show SMILES Nc1nc2c(nc(N)[nH]c2=O)n1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C10H14N6O5/c11-9-14-6-3(7(20)15-9)13-10(12)16(6)8-5(19)4(18)2(1-17)21-8/h2,4-5,8,17-19H,1H2,(H2,12,13)(H3,11,14,15,20)/t2-,4-,5-,8-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Compound was tested for the inhibitory activity against purine nucleoside phosphorylase (PNP) |
J Med Chem 35: 1605-9 (1992)
BindingDB Entry DOI: 10.7270/Q2KW5GPH |
More data for this Ligand-Target Pair | |
Purine nucleoside phosphorylase
(Homo sapiens (Human)) | BDBM50005919
(2,6-Diamino-7-benzyl-3,5-dihydro-pyrrolo[3,2-d]pyr...)Show InChI InChI=1S/C13H13N5O/c14-11-8(6-7-4-2-1-3-5-7)9-10(16-11)12(19)18-13(15)17-9/h1-5,16H,6,14H2,(H3,15,17,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Compound was tested for the inhibitory activity against purine nucleoside phosphorylase (PNP) |
J Med Chem 35: 1605-9 (1992)
BindingDB Entry DOI: 10.7270/Q2KW5GPH |
More data for this Ligand-Target Pair | |
Purine nucleoside phosphorylase
(Homo sapiens (Human)) | BDBM50005918
(2,6-Diamino-7-furan-2-ylmethyl-3,5-dihydro-pyrrolo...)Show InChI InChI=1S/C11H11N5O2/c12-9-6(4-5-2-1-3-18-5)7-8(14-9)10(17)16-11(13)15-7/h1-3,14H,4,12H2,(H3,13,15,16,17) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 5.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Compound was tested for the inhibitory activity against purine nucleoside phosphorylase (PNP) |
J Med Chem 35: 1605-9 (1992)
BindingDB Entry DOI: 10.7270/Q2KW5GPH |
More data for this Ligand-Target Pair | |
Purine nucleoside phosphorylase
(Homo sapiens (Human)) | BDBM50005921
(2,6-Diamino-7-(2-methoxy-benzyl)-3,5-dihydro-pyrro...)Show InChI InChI=1S/C14H15N5O2/c1-21-9-5-3-2-4-7(9)6-8-10-11(17-12(8)15)13(20)19-14(16)18-10/h2-5,17H,6,15H2,1H3,(H3,16,18,19,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 3.14E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Compound was tested for the inhibitory activity against purine nucleoside phosphorylase (PNP) |
J Med Chem 35: 1605-9 (1992)
BindingDB Entry DOI: 10.7270/Q2KW5GPH |
More data for this Ligand-Target Pair | |