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Compile Data Set for Download or QSAR

Found 189 hits with Last Name = 'boardman' and Initial = 'p'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342570
PNG
((E)-4-bromo-3-(2-oxo-2-(pyridin-3-yl)ethylidene)in...)
Show SMILES Brc1cccc2NC(=O)\C(=C\C(=O)c3cccnc3)c12
Show InChI InChI=1S/C15H9BrN2O2/c16-11-4-1-5-12-14(11)10(15(20)18-12)7-13(19)9-3-2-6-17-8-9/h1-8H,(H,18,20)/b10-7+
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250n/an/an/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using ZGBC as a substrate after 30 to 60 mins by fluorometric assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342570
PNG
((E)-4-bromo-3-(2-oxo-2-(pyridin-3-yl)ethylidene)in...)
Show SMILES Brc1cccc2NC(=O)\C(=C\C(=O)c3cccnc3)c12
Show InChI InChI=1S/C15H9BrN2O2/c16-11-4-1-5-12-14(11)10(15(20)18-12)7-13(19)9-3-2-6-17-8-9/h1-8H,(H,18,20)/b10-7+
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400n/an/an/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342568
PNG
((E)-1-benzyl-4-chloro-3-(2-oxo-2-(pyridin-3-yl)eth...)
Show SMILES Clc1cccc2N(Cc3ccccc3)C(=O)\C(=C\C(=O)c3cccnc3)c12
Show InChI InChI=1S/C22H15ClN2O2/c23-18-9-4-10-19-21(18)17(12-20(26)16-8-5-11-24-13-16)22(27)25(19)14-15-6-2-1-3-7-15/h1-13H,14H2/b17-12+
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410n/an/an/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342571
PNG
((E)-5-bromo-3-(2-oxo-2-(pyridin-3-yl)ethylidene)in...)
Show SMILES Brc1ccc2NC(=O)\C(=C\C(=O)c3cccnc3)c2c1
Show InChI InChI=1S/C15H9BrN2O2/c16-10-3-4-13-11(6-10)12(15(20)18-13)7-14(19)9-2-1-5-17-8-9/h1-8H,(H,18,20)/b12-7+
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680n/an/an/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using ZGBC as a substrate after 30 to 60 mins by fluorometric assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342562
PNG
((E)-4-chloro-3-(2-oxopropylidene)indolin-2-one | C...)
Show SMILES CC(=O)C=C1C(=O)Nc2cccc(Cl)c12 |w:3.2|
Show InChI InChI=1S/C11H8ClNO2/c1-6(14)5-7-10-8(12)3-2-4-9(10)13-11(7)15/h2-5H,1H3,(H,13,15)
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700n/an/an/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342563
PNG
((E)-5-chloro-3-(2-oxopropylidene)indolin-2-one | C...)
Show SMILES CC(=O)C=C1C(=O)Nc2ccc(Cl)cc12 |w:3.2|
Show InChI InChI=1S/C11H8ClNO2/c1-6(14)4-9-8-5-7(12)2-3-10(8)13-11(9)15/h2-5H,1H3,(H,13,15)
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900n/an/an/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342568
PNG
((E)-1-benzyl-4-chloro-3-(2-oxo-2-(pyridin-3-yl)eth...)
Show SMILES Clc1cccc2N(Cc3ccccc3)C(=O)\C(=C\C(=O)c3cccnc3)c12
Show InChI InChI=1S/C22H15ClN2O2/c23-18-9-4-10-19-21(18)17(12-20(26)16-8-5-11-24-13-16)22(27)25(19)14-15-6-2-1-3-7-15/h1-13H,14H2/b17-12+
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1.00E+3n/an/an/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using ZGBC as a substrate after 30 to 60 mins by fluorometric assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342565
PNG
((E)-4-chloro-3-(2-oxo-2-(pyridin-3-yl)ethylidene)i...)
Show SMILES Clc1cccc2NC(=O)\C(=C\C(=O)c3cccnc3)c12
Show InChI InChI=1S/C15H9ClN2O2/c16-11-4-1-5-12-14(11)10(15(20)18-12)7-13(19)9-3-2-6-17-8-9/h1-8H,(H,18,20)/b10-7+
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1.30E+3n/an/an/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342557
PNG
(5,5'-oxydiindoline-2,3-dione | CHEMBL1770389)
Show SMILES O=C1Nc2ccc(Oc3ccc4NC(=O)C(=O)c4c3)cc2C1=O
Show InChI InChI=1S/C16H8N2O5/c19-13-9-5-7(1-3-11(9)17-15(13)21)23-8-2-4-12-10(6-8)14(20)16(22)18-12/h1-6H,(H,17,19,21)(H,18,20,22)
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3.00E+3n/an/an/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342571
PNG
((E)-5-bromo-3-(2-oxo-2-(pyridin-3-yl)ethylidene)in...)
Show SMILES Brc1ccc2NC(=O)\C(=C\C(=O)c3cccnc3)c2c1
Show InChI InChI=1S/C15H9BrN2O2/c16-10-3-4-13-11(6-10)12(15(20)18-13)7-14(19)9-2-1-5-17-8-9/h1-8H,(H,18,20)/b12-7+
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3.00E+3n/an/an/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342566
PNG
((E)-4-chloro-3-(2-oxo-2-phenylethylidene)indolin-2...)
Show SMILES Clc1cccc2NC(=O)\C(=C\C(=O)c3ccccc3)c12
Show InChI InChI=1S/C16H10ClNO2/c17-12-7-4-8-13-15(12)11(16(20)18-13)9-14(19)10-5-2-1-3-6-10/h1-9H,(H,18,20)/b11-9+
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3.30E+3n/an/an/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Interferon-induced, double-stranded RNA-activated protein kinase


(Homo sapiens (Human))
BDBM50347871
PNG
(CHEMBL1802618)
Show SMILES Cc1[nH]c2ccccc2c1-c1ccnc(NCCc2c[nH]c3ccccc23)n1
Show InChI InChI=1S/C23H21N5/c1-15-22(18-7-3-5-9-20(18)27-15)21-11-13-25-23(28-21)24-12-10-16-14-26-19-8-4-2-6-17(16)19/h2-9,11,13-14,26-27H,10,12H2,1H3,(H,24,25,28)
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3.40E+3n/an/an/an/an/an/an/an/a



Weill Cornell Medical College

Curated by ChEMBL


Assay Description
Competitive inhibition of human recombinant PKR


Bioorg Med Chem Lett 21: 4108-14 (2011)


Article DOI: 10.1016/j.bmcl.2011.04.149
BindingDB Entry DOI: 10.7270/Q2KK9C4H
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342567
PNG
((E)-4-chloro-1-methyl-3-(2-oxo-2-(pyridin-3-yl)eth...)
Show SMILES CN1C(=O)\C(=C\C(=O)c2cccnc2)c2c1cccc2Cl
Show InChI InChI=1S/C16H11ClN2O2/c1-19-13-6-2-5-12(17)15(13)11(16(19)21)8-14(20)10-4-3-7-18-9-10/h2-9H,1H3/b11-8+
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4.00E+3n/an/an/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342553
PNG
((E)-6-chloro-3-(2-oxo-2-(pyridin-3-yl)ethylidene)i...)
Show SMILES Clc1ccc2\C(=C/C(=O)c3cccnc3)C(=O)Nc2c1
Show InChI InChI=1S/C15H9ClN2O2/c16-10-3-4-11-12(15(20)18-13(11)6-10)7-14(19)9-2-1-5-17-8-9/h1-8H,(H,18,20)/b12-7+
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5.30E+3n/an/an/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342564
PNG
((E)-6-fluoro-3-(2-oxopropylidene)indolin-2-one | C...)
Show SMILES CC(=O)C=C1C(=O)Nc2cc(F)ccc12 |w:3.2|
Show InChI InChI=1S/C11H8FNO2/c1-6(14)4-9-8-3-2-7(12)5-10(8)13-11(9)15/h2-5H,1H3,(H,13,15)
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5.40E+3n/an/an/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50132009
PNG
(3-(2-Oxo-propylidene)-1,3-dihydro-indol-2-one | CH...)
Show SMILES CC(=O)C=C1C(=O)Nc2ccccc12 |w:3.2|
Show InChI InChI=1S/C11H9NO2/c1-7(13)6-9-8-4-2-3-5-10(8)12-11(9)14/h2-6H,1H3,(H,12,14)
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1.00E+4n/an/an/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342560
PNG
(1,1'-methylenediindoline-2,3-dione | CHEMBL1770393)
Show SMILES O=C1N(CN2C(=O)C(=O)c3ccccc23)c2ccccc2C1=O
Show InChI InChI=1S/C17H10N2O4/c20-14-10-5-1-3-7-12(10)18(16(14)22)9-19-13-8-4-2-6-11(13)15(21)17(19)23/h1-8H,9H2
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1.00E+4n/an/an/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342559
PNG
(1,1'-(4,6-dimethyl-1,3-phenylene)bis(methylene)dii...)
Show SMILES Cc1cc(C)c(CN2C(=O)C(=O)c3ccccc23)cc1CN1C(=O)C(=O)c2ccccc12
Show InChI InChI=1S/C26H20N2O4/c1-15-11-16(2)18(14-28-22-10-6-4-8-20(22)24(30)26(28)32)12-17(15)13-27-21-9-5-3-7-19(21)23(29)25(27)31/h3-12H,13-14H2,1-2H3
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1.10E+4n/an/an/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342569
PNG
((E)-3-(2-oxo-2-(pyridin-3-yl)ethylidene)indolin-2-...)
Show SMILES O=C(\C=C1\C(=O)Nc2ccccc12)c1cccnc1
Show InChI InChI=1S/C15H10N2O2/c18-14(10-4-3-7-16-9-10)8-12-11-5-1-2-6-13(11)17-15(12)19/h1-9H,(H,17,19)/b12-8+
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1.20E+4n/an/an/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342558
PNG
(5,5'-methylenediindoline-2,3-dione | CHEMBL1770390)
Show SMILES O=C1Nc2ccc(Cc3ccc4NC(=O)C(=O)c4c3)cc2C1=O
Show InChI InChI=1S/C17H10N2O4/c20-14-10-6-8(1-3-12(10)18-16(14)22)5-9-2-4-13-11(7-9)15(21)17(23)19-13/h1-4,6-7H,5H2,(H,18,20,22)(H,19,21,23)
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1.50E+4n/an/an/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342561
PNG
((2-oxoindolin-3-ylidene)indolin-2-one | (E)-[3,3'-...)
Show SMILES O=C1Nc2ccccc2\C1=C1/C(=O)Nc2ccccc12
Show InChI InChI=1S/C16H10N2O2/c19-15-13(9-5-1-3-7-11(9)17-15)14-10-6-2-4-8-12(10)18-16(14)20/h1-8H,(H,17,19)(H,18,20)/b14-13+
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4.10E+4n/an/an/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342582
PNG
((E)-4-chloro-3-(2-(4-chlorophenyl)-2-oxoethylidene...)
Show SMILES Clc1ccc(cc1)C(=O)\C=C1\C(=O)Nc2cccc(Cl)c12
Show InChI InChI=1S/C16H9Cl2NO2/c17-10-6-4-9(5-7-10)14(20)8-11-15-12(18)2-1-3-13(15)19-16(11)21/h1-8H,(H,19,21)/b11-8+
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n/an/a 90n/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using ZGBC as a substrate after 30 to 60 mins by fluorometric assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Interferon-induced, double-stranded RNA-activated protein kinase


(Homo sapiens (Human))
BDBM50347891
PNG
(CHEMBL1802629)
Show SMILES Cc1[nH]c2ccccc2c1-c1ccnc(Nc2cccnc2)n1
Show InChI InChI=1S/C18H15N5/c1-12-17(14-6-2-3-7-15(14)21-12)16-8-10-20-18(23-16)22-13-5-4-9-19-11-13/h2-11,21H,1H3,(H,20,22,23)
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n/an/a 100n/an/an/an/an/an/a



Weill Cornell Medical College

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assay


Bioorg Med Chem Lett 21: 4108-14 (2011)


Article DOI: 10.1016/j.bmcl.2011.04.149
BindingDB Entry DOI: 10.7270/Q2KK9C4H
More data for this
Ligand-Target Pair
Interferon-induced, double-stranded RNA-activated protein kinase


(Homo sapiens (Human))
BDBM50347876
PNG
(CHEMBL1802782)
Show SMILES CN1CCN(CC1)c1ccc(Nc2nccc(n2)-c2c(C)[nH]c3ccc(Cl)cc23)cc1
Show InChI InChI=1S/C24H25ClN6/c1-16-23(20-15-17(25)3-8-21(20)27-16)22-9-10-26-24(29-22)28-18-4-6-19(7-5-18)31-13-11-30(2)12-14-31/h3-10,15,27H,11-14H2,1-2H3,(H,26,28,29)
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n/an/a 100n/an/an/an/an/an/a



Weill Cornell Medical College

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assay


Bioorg Med Chem Lett 21: 4108-14 (2011)


Article DOI: 10.1016/j.bmcl.2011.04.149
BindingDB Entry DOI: 10.7270/Q2KK9C4H
More data for this
Ligand-Target Pair
Interferon-induced, double-stranded RNA-activated protein kinase


(Homo sapiens (Human))
BDBM50347926
PNG
(CHEMBL1802778)
Show SMILES Cc1[nH]c2ccccc2c1-c1ccnc(Nc2ccc(F)cc2)n1
Show InChI InChI=1S/C19H15FN4/c1-12-18(15-4-2-3-5-16(15)22-12)17-10-11-21-19(24-17)23-14-8-6-13(20)7-9-14/h2-11,22H,1H3,(H,21,23,24)
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n/an/a 150n/an/an/an/an/an/a



Weill Cornell Medical College

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assay


Bioorg Med Chem Lett 21: 4108-14 (2011)


Article DOI: 10.1016/j.bmcl.2011.04.149
BindingDB Entry DOI: 10.7270/Q2KK9C4H
More data for this
Ligand-Target Pair
Interferon-induced, double-stranded RNA-activated protein kinase


(Homo sapiens (Human))
BDBM50173832
PNG
(4-(3-chloro-4-fluorophenylamino)-6-(pyridin-3-ylme...)
Show SMILES Fc1ccc(Nc2c(cnc3cnc(NCc4cccnc4)cc23)C#N)cc1Cl
Show InChI InChI=1S/C21H14ClFN6/c22-17-6-15(3-4-18(17)23)29-21-14(8-24)11-26-19-12-28-20(7-16(19)21)27-10-13-2-1-5-25-9-13/h1-7,9,11-12H,10H2,(H,26,29)(H,27,28)
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n/an/a 250n/an/an/an/an/an/a



Weill Cornell Medical College

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assay


Bioorg Med Chem Lett 21: 4108-14 (2011)


Article DOI: 10.1016/j.bmcl.2011.04.149
BindingDB Entry DOI: 10.7270/Q2KK9C4H
More data for this
Ligand-Target Pair
Interferon-induced, double-stranded RNA-activated protein kinase


(Homo sapiens (Human))
BDBM50230828
PNG
(5-(4-fluorophenyl)-2-ureidothiophene-3-carboxamide...)
Show SMILES NC(=O)Nc1sc(cc1C(N)=O)-c1ccc(F)cc1
Show InChI InChI=1S/C12H10FN3O2S/c13-7-3-1-6(2-4-7)9-5-8(10(14)17)11(19-9)16-12(15)18/h1-5H,(H2,14,17)(H3,15,16,18)
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n/an/a 250n/an/an/an/an/an/a



Weill Cornell Medical College

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assay


Bioorg Med Chem Lett 21: 4108-14 (2011)


Article DOI: 10.1016/j.bmcl.2011.04.149
BindingDB Entry DOI: 10.7270/Q2KK9C4H
More data for this
Ligand-Target Pair
Interferon-induced, double-stranded RNA-activated protein kinase


(Homo sapiens (Human))
BDBM50347887
PNG
(CHEMBL1802769)
Show SMILES Cc1[nH]c2ccccc2c1-c1ccnc(Nc2cccc(Cl)c2)n1
Show InChI InChI=1S/C19H15ClN4/c1-12-18(15-7-2-3-8-16(15)22-12)17-9-10-21-19(24-17)23-14-6-4-5-13(20)11-14/h2-11,22H,1H3,(H,21,23,24)
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n/an/a 300n/an/an/an/an/an/a



Weill Cornell Medical College

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assay


Bioorg Med Chem Lett 21: 4108-14 (2011)


Article DOI: 10.1016/j.bmcl.2011.04.149
BindingDB Entry DOI: 10.7270/Q2KK9C4H
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342568
PNG
((E)-1-benzyl-4-chloro-3-(2-oxo-2-(pyridin-3-yl)eth...)
Show SMILES Clc1cccc2N(Cc3ccccc3)C(=O)\C(=C\C(=O)c3cccnc3)c12
Show InChI InChI=1S/C22H15ClN2O2/c23-18-9-4-10-19-21(18)17(12-20(26)16-8-5-11-24-13-16)22(27)25(19)14-15-6-2-1-3-7-15/h1-13H,14H2/b17-12+
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n/an/a 360n/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using ZGBC as a substrate after 30 to 60 mins by fluorometric assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342554
PNG
((E)-6-bromo-3-(2-oxo-2-(pyridin-3-yl)ethylidene)in...)
Show SMILES Brc1ccc2\C(=C/C(=O)c3cccnc3)C(=O)Nc2c1
Show InChI InChI=1S/C15H9BrN2O2/c16-10-3-4-11-12(15(20)18-13(11)6-10)7-14(19)9-2-1-5-17-8-9/h1-8H,(H,18,20)/b12-7+
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n/an/a 360n/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using ZGBC as a substrate after 30 to 60 mins by fluorometric assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342571
PNG
((E)-5-bromo-3-(2-oxo-2-(pyridin-3-yl)ethylidene)in...)
Show SMILES Brc1ccc2NC(=O)\C(=C\C(=O)c3cccnc3)c2c1
Show InChI InChI=1S/C15H9BrN2O2/c16-10-3-4-13-11(6-10)12(15(20)18-13)7-14(19)9-2-1-5-17-8-9/h1-8H,(H,18,20)/b12-7+
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n/an/a 560n/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using ZGBC as a substrate after 30 to 60 mins by fluorometric assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342590
PNG
((E)-4-chloro-3-(2-oxo-2-(pyridin-3-yl)ethylidene)-...)
Show SMILES Clc1cccc2N(C(=O)\C(=C\C(=O)c3cccnc3)c12)c1ccccc1
Show InChI InChI=1S/C21H13ClN2O2/c22-17-9-4-10-18-20(17)16(12-19(25)14-6-5-11-23-13-14)21(26)24(18)15-7-2-1-3-8-15/h1-13H/b16-12+
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n/an/a 570n/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using ZGBC as a substrate after 30 to 60 mins by fluorometric assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Interferon-induced, double-stranded RNA-activated protein kinase


(Homo sapiens (Human))
BDBM7401
PNG
((2 Z,3 E)-6-Bromoindirubin-3 -oxime | (3E)-6-bromo...)
Show SMILES Brc1ccc2C(C(=O)Nc2c1)c1[nH]c2ccccc2c1N=O
Show InChI InChI=1S/C16H10BrN3O2/c17-8-5-6-9-12(7-8)19-16(21)13(9)15-14(20-22)10-3-1-2-4-11(10)18-15/h1-7,13,18H,(H,19,21)
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n/an/a 600n/an/an/an/an/an/a



Weill Cornell Medical College

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assay


Bioorg Med Chem Lett 21: 4108-14 (2011)


Article DOI: 10.1016/j.bmcl.2011.04.149
BindingDB Entry DOI: 10.7270/Q2KK9C4H
More data for this
Ligand-Target Pair
Interferon-induced, double-stranded RNA-activated protein kinase


(Homo sapiens (Human))
BDBM50347889
PNG
(CHEMBL1802630)
Show SMILES Cc1[nH]c2ccccc2c1-c1ccnc(Nc2ccc(Cl)cc2)n1
Show InChI InChI=1S/C19H15ClN4/c1-12-18(15-4-2-3-5-16(15)22-12)17-10-11-21-19(24-17)23-14-8-6-13(20)7-9-14/h2-11,22H,1H3,(H,21,23,24)
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n/an/a 600n/an/an/an/an/an/a



Weill Cornell Medical College

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assay


Bioorg Med Chem Lett 21: 4108-14 (2011)


Article DOI: 10.1016/j.bmcl.2011.04.149
BindingDB Entry DOI: 10.7270/Q2KK9C4H
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342597
PNG
((E)-methyl 4-((4-chloro-2-oxo-3-(2-oxo-2-(pyridin-...)
Show SMILES COC(=O)c1ccc(CN2C(=O)\C(=C\C(=O)c3cccnc3)c3c2cccc3Cl)cc1
Show InChI InChI=1S/C24H17ClN2O4/c1-31-24(30)16-9-7-15(8-10-16)14-27-20-6-2-5-19(25)22(20)18(23(27)29)12-21(28)17-4-3-11-26-13-17/h2-13H,14H2,1H3/b18-12+
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n/an/a 660n/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using ZGBC as a substrate after 30 to 60 mins by fluorometric assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342581
PNG
((E)-4-chloro-3-(2-(3-chlorophenyl)-2-oxoethylidene...)
Show SMILES Clc1cccc(c1)C(=O)\C=C1\C(=O)Nc2cccc(Cl)c12
Show InChI InChI=1S/C16H9Cl2NO2/c17-10-4-1-3-9(7-10)14(20)8-11-15-12(18)5-2-6-13(15)19-16(11)21/h1-8H,(H,19,21)/b11-8+
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n/an/a 700n/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342583
PNG
((E)-4-chloro-3-(2-(2-methoxyphenyl)-2-oxoethyliden...)
Show SMILES COc1ccccc1C(=O)\C=C1\C(=O)Nc2cccc(Cl)c12
Show InChI InChI=1S/C17H12ClNO3/c1-22-15-8-3-2-5-10(15)14(20)9-11-16-12(18)6-4-7-13(16)19-17(11)21/h2-9H,1H3,(H,19,21)/b11-9+
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n/an/a 740n/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using ZGBC as a substrate after 30 to 60 mins by fluorometric assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Interferon-induced, double-stranded RNA-activated protein kinase


(Homo sapiens (Human))
BDBM50347920
PNG
(CHEMBL1802486)
Show SMILES O=C1NCc2c1c1c3ccccc3n3C4CCC(O4)n4c5ccccc5c2c4c13
Show InChI InChI=1S/C24H17N3O2/c28-24-21-14(11-25-24)19-12-5-1-3-7-15(12)26-17-9-10-18(29-17)27-16-8-4-2-6-13(16)20(21)23(27)22(19)26/h1-8,17-18H,9-11H2,(H,25,28)
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n/an/a 750n/an/an/an/an/an/a



Weill Cornell Medical College

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assay


Bioorg Med Chem Lett 21: 4108-14 (2011)


Article DOI: 10.1016/j.bmcl.2011.04.149
BindingDB Entry DOI: 10.7270/Q2KK9C4H
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342590
PNG
((E)-4-chloro-3-(2-oxo-2-(pyridin-3-yl)ethylidene)-...)
Show SMILES Clc1cccc2N(C(=O)\C(=C\C(=O)c3cccnc3)c12)c1ccccc1
Show InChI InChI=1S/C21H13ClN2O2/c22-17-9-4-10-18-20(17)16(12-19(25)14-6-5-11-23-13-14)21(26)24(18)15-7-2-1-3-8-15/h1-13H/b16-12+
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n/an/a 800n/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342582
PNG
((E)-4-chloro-3-(2-(4-chlorophenyl)-2-oxoethylidene...)
Show SMILES Clc1ccc(cc1)C(=O)\C=C1\C(=O)Nc2cccc(Cl)c12
Show InChI InChI=1S/C16H9Cl2NO2/c17-10-6-4-9(5-7-10)14(20)8-11-15-12(18)2-1-3-13(15)19-16(11)21/h1-8H,(H,19,21)/b11-8+
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n/an/a 800n/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342577
PNG
((E)-4-chloro-3-(2-oxo-2-(pyridin-2-yl)ethylidene)i...)
Show SMILES Clc1cccc2NC(=O)\C(=C\C(=O)c3ccccn3)c12
Show InChI InChI=1S/C15H9ClN2O2/c16-10-4-3-6-12-14(10)9(15(20)18-12)8-13(19)11-5-1-2-7-17-11/h1-8H,(H,18,20)/b9-8+
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n/an/a 890n/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using ZGBC as a substrate after 30 to 60 mins by fluorometric assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342583
PNG
((E)-4-chloro-3-(2-(2-methoxyphenyl)-2-oxoethyliden...)
Show SMILES COc1ccccc1C(=O)\C=C1\C(=O)Nc2cccc(Cl)c12
Show InChI InChI=1S/C17H12ClNO3/c1-22-15-8-3-2-5-10(15)14(20)9-11-16-12(18)6-4-7-13(16)19-17(11)21/h2-9H,1H3,(H,19,21)/b11-9+
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n/an/a 900n/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342565
PNG
((E)-4-chloro-3-(2-oxo-2-(pyridin-3-yl)ethylidene)i...)
Show SMILES Clc1cccc2NC(=O)\C(=C\C(=O)c3cccnc3)c12
Show InChI InChI=1S/C15H9ClN2O2/c16-11-4-1-5-12-14(11)10(15(20)18-12)7-13(19)9-3-2-6-17-8-9/h1-8H,(H,18,20)/b10-7+
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n/an/a 900n/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342570
PNG
((E)-4-bromo-3-(2-oxo-2-(pyridin-3-yl)ethylidene)in...)
Show SMILES Brc1cccc2NC(=O)\C(=C\C(=O)c3cccnc3)c12
Show InChI InChI=1S/C15H9BrN2O2/c16-11-4-1-5-12-14(11)10(15(20)18-12)7-13(19)9-3-2-6-17-8-9/h1-8H,(H,18,20)/b10-7+
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n/an/a 900n/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342580
PNG
((E)-4-chloro-3-(2-(6-methoxypyridin-3-yl)-2-oxoeth...)
Show SMILES COc1ccncc1C(=O)\C=C1\C(=O)Nc2cccc(Cl)c12
Show InChI InChI=1S/C16H11ClN2O3/c1-22-14-5-6-18-8-10(14)13(20)7-9-15-11(17)3-2-4-12(15)19-16(9)21/h2-8H,1H3,(H,19,21)/b9-7+
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n/an/a 950n/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using ZGBC as a substrate after 30 to 60 mins by fluorometric assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342579
PNG
((E)-3-(2-(5-bromopyridin-3-yl)-2-oxoethylidene)-4-...)
Show SMILES Clc1cccc2NC(=O)\C(=C\C(=O)c3cncc(Br)c3)c12
Show InChI InChI=1S/C15H8BrClN2O2/c16-9-4-8(6-18-7-9)13(20)5-10-14-11(17)2-1-3-12(14)19-15(10)21/h1-7H,(H,19,21)/b10-5+
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n/an/a 970n/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using ZGBC as a substrate after 30 to 60 mins by fluorometric assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342578
PNG
((E)-4-chloro-3-(2-oxo-2-(pyridin-4-yl)ethylidene)i...)
Show SMILES Clc1cccc2NC(=O)\C(=C\C(=O)c3ccncc3)c12
Show InChI InChI=1S/C15H9ClN2O2/c16-11-2-1-3-12-14(11)10(15(20)18-12)8-13(19)9-4-6-17-7-5-9/h1-8H,(H,18,20)/b10-8+
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n/an/a 1.00E+3n/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using ZGBC as a substrate after 30 to 60 mins by fluorometric assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342570
PNG
((E)-4-bromo-3-(2-oxo-2-(pyridin-3-yl)ethylidene)in...)
Show SMILES Brc1cccc2NC(=O)\C(=C\C(=O)c3cccnc3)c12
Show InChI InChI=1S/C15H9BrN2O2/c16-11-4-1-5-12-14(11)10(15(20)18-12)7-13(19)9-3-2-6-17-8-9/h1-8H,(H,18,20)/b10-7+
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n/an/a 1.00E+3n/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using ZGBC as a substrate after 30 to 60 mins by fluorometric assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342584
PNG
((E)-4-chloro-3-(2-(3-methoxyphenyl)-2-oxoethyliden...)
Show SMILES COc1cccc(c1)C(=O)\C=C1\C(=O)Nc2cccc(Cl)c12
Show InChI InChI=1S/C17H12ClNO3/c1-22-11-5-2-4-10(8-11)15(20)9-12-16-13(18)6-3-7-14(16)19-17(12)21/h2-9H,1H3,(H,19,21)/b12-9+
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n/an/a 1.00E+3n/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2


(Homo sapiens (Human))
BDBM50342593
PNG
((E)-4-chloro-3-(2-oxo-2-(pyridin-3-yl)ethylidene)-...)
Show SMILES Clc1cccc2N(CCCc3ccccc3)C(=O)\C(=C\C(=O)c3cccnc3)c12
Show InChI InChI=1S/C24H19ClN2O2/c25-20-11-4-12-21-23(20)19(15-22(28)18-10-5-13-26-16-18)24(29)27(21)14-6-9-17-7-2-1-3-8-17/h1-5,7-8,10-13,15-16H,6,9,14H2/b19-15+
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n/an/a 1.00E+3n/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human transglutaminase 2 using ZGBC as a substrate after 30 to 60 mins by fluorometric assay


Bioorg Med Chem Lett 21: 2692-6 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.037
BindingDB Entry DOI: 10.7270/Q2CN7471
More data for this
Ligand-Target Pair
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