Compile Data Set for Download or QSAR

Found 68 hits with Last Name = 'chavchich' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50258940 (CHEMBL4086362) Show SMILES [Na+].[Na+].[Na+].[Na+].Nc1nc2n(CC(COCCP([O-])([O-])=O)COCP([O-])([O-])=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C12H21N5O9P2.4Na/c13-12-15-10-9(11(18)16-12)14-6-17(10)3-8(5-26-7-28(22,23)24)4-25-1-2-27(19,20)21;;;;/h6,8H,1-5,7H2,(H2,19,20,21)(H2,22,23,24)(H3,13,15,16,18);;;;/q;4*+1/p-4	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human HGPRT using PRib-PP as the substrate by spectrophotometric method				J Med Chem 60: 7539-7554 (2017) Article DOI: 10.1021/acs.jmedchem.7b00926 BindingDB Entry DOI: 10.7270/Q2J968T1
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50059910 (CHEMBL3394315) Show SMILES Nc1nc2n(CCN(CCP(O)(O)=O)COCCP(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C12H22N6O8P2/c13-12-15-10-9(11(19)16-12)14-7-18(10)2-1-17(3-5-27(20,21)22)8-26-4-6-28(23,24)25/h7H,1-6,8H2,(H2,20,21,22)(H2,23,24,25)(H3,13,15,16,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of human HGPRT				J Med Chem 58: 827-46 (2015) Article DOI: 10.1021/jm501416t BindingDB Entry DOI: 10.7270/Q2HM5B3V
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50427810 (CHEMBL2325752) Show SMILES Nc1nc2n(CC(COCP(O)(O)=O)COCP(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C11H19N5O9P2/c12-11-14-9-8(10(17)15-11)13-4-16(9)1-7(2-24-5-26(18,19)20)3-25-6-27(21,22)23/h4,7H,1-3,5-6H2,(H2,18,19,20)(H2,21,22,23)(H3,12,14,15,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of human N-terminal hexahistidine-tagged HGPRT				J Med Chem 56: 2513-26 (2013) Article DOI: 10.1021/jm301893b BindingDB Entry DOI: 10.7270/Q2MW2JGT
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50059908 (CHEMBL3394327) Show SMILES Nc1nc2n(CCN(CCOCCP(O)(O)=O)CCP(O)(O)=O)c(Br)nc2c(=O)[nH]1 Show InChI InChI=1S/C13H23BrN6O8P2/c14-12-16-9-10(17-13(15)18-11(9)21)20(12)2-1-19(4-7-29(22,23)24)3-5-28-6-8-30(25,26)27/h1-8H2,(H2,22,23,24)(H2,25,26,27)(H3,15,17,18,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of human HGPRT				J Med Chem 58: 827-46 (2015) Article DOI: 10.1021/jm501416t BindingDB Entry DOI: 10.7270/Q2HM5B3V
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50392261 (CHEMBL2153480) Show SMILES Nc1nc2n(CCN(CCC#N)CCP(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C12H18N7O4P/c13-2-1-3-18(6-7-24(21,22)23)4-5-19-8-15-9-10(19)16-12(14)17-11(9)20/h8H,1,3-7H2,(H2,21,22,23)(H3,14,16,17,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of human HGPRT				J Med Chem 58: 827-46 (2015) Article DOI: 10.1021/jm501416t BindingDB Entry DOI: 10.7270/Q2HM5B3V
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50059909 (CHEMBL3394316) Show SMILES Nc1nc2n(CCN(CCOCCP(O)(O)=O)CCP(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C13H24N6O8P2/c14-13-16-11-10(12(20)17-13)15-9-19(11)2-1-18(4-7-28(21,22)23)3-5-27-6-8-29(24,25)26/h9H,1-8H2,(H2,21,22,23)(H2,24,25,26)(H3,14,16,17,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human HGPRT using PRib-PP as substrate by Hanes-plot based method				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113416 BindingDB Entry DOI: 10.7270/Q2T43XWD
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50059909 (CHEMBL3394316) Show SMILES Nc1nc2n(CCN(CCOCCP(O)(O)=O)CCP(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C13H24N6O8P2/c14-13-16-11-10(12(20)17-13)15-9-19(11)2-1-18(4-7-28(21,22)23)3-5-27-6-8-29(24,25)26/h9H,1-8H2,(H2,21,22,23)(H2,24,25,26)(H3,14,16,17,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of human HGPRT				J Med Chem 58: 827-46 (2015) Article DOI: 10.1021/jm501416t BindingDB Entry DOI: 10.7270/Q2HM5B3V
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50268142 (CHEMBL4098313) Show SMILES [Na+].[Na+].[Na+].[Na+].Nc1nc2n(CC(COCCP([O-])([O-])=O)COCCP([O-])([O-])=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C13H23N5O9P2/c14-13-16-11-10(12(19)17-13)15-8-18(11)5-9(6-26-1-3-28(20,21)22)7-27-2-4-29(23,24)25/h8-9H,1-7H2,(H2,20,21,22)(H2,23,24,25)(H3,14,16,17,19)/p-4	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nám. 2, CZ-16610 Prague 6, Czech Republic. Curated by ChEMBL					Assay Description Inhibition of N-terminal hexa-histidine-tagged human HGPRT using PRib-PP as substrate in presence of guanine by Hanes plot analysis				Bioorg Med Chem 25: 4008-4030 (2017) Article DOI: 10.1016/j.bmc.2017.05.048 BindingDB Entry DOI: 10.7270/Q2NS0XCJ
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50258937 (CHEMBL4067618) Show SMILES [Na+].[Na+].[Na+].[Na+].Nc1nc2n(CC(COCCP([O-])([O-])=O)COCP([O-])([O-])=O)ccc2c(=O)[nH]1 Show InChI InChI=1S/C13H22N4O9P2.4Na/c14-13-15-11-10(12(18)16-13)1-2-17(11)5-9(7-26-8-28(22,23)24)6-25-3-4-27(19,20)21;;;;/h1-2,9H,3-8H2,(H2,19,20,21)(H2,22,23,24)(H3,14,15,16,18);;;;/q;4*+1/p-4	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human HGPRT using PRib-PP as the substrate by spectrophotometric method				J Med Chem 60: 7539-7554 (2017) Article DOI: 10.1021/acs.jmedchem.7b00926 BindingDB Entry DOI: 10.7270/Q2J968T1
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50258941 (CHEMBL4078513) Show SMILES [Na+].[Na+].[Na+].[Na+].Nc1nc2n(CC(COCCP([O-])([O-])=O)COCP([O-])([O-])=O)c(Br)nc2c(=O)[nH]1 Show InChI InChI=1S/C12H20BrN5O9P2.4Na/c13-11-15-8-9(16-12(14)17-10(8)19)18(11)3-7(5-27-6-29(23,24)25)4-26-1-2-28(20,21)22;;;;/h7H,1-6H2,(H2,20,21,22)(H2,23,24,25)(H3,14,16,17,19);;;;/q;4*+1/p-4	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human HGPRT using PRib-PP as the substrate by spectrophotometric method				J Med Chem 60: 7539-7554 (2017) Article DOI: 10.1021/acs.jmedchem.7b00926 BindingDB Entry DOI: 10.7270/Q2J968T1
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50569742 (CHEMBL4846343) Show SMILES Nc1nc2n(CC3CN(CCP([O-])([O-])=O)CCN3CCP([O-])([O-])=O)cnc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human HGPRT using PRib-PP as substrate by Hanes-plot based method				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113416 BindingDB Entry DOI: 10.7270/Q2T43XWD
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50059913 (CHEMBL3394312) Show SMILES OP(O)(=O)CCOCN(CCn1cnc2c1nc[nH]c2=O)CCP(O)(O)=O Show InChI InChI=1S/C12H21N5O8P2/c18-12-10-11(13-7-14-12)17(8-15-10)2-1-16(3-5-26(19,20)21)9-25-4-6-27(22,23)24/h7-8H,1-6,9H2,(H,13,14,18)(H2,19,20,21)(H2,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of human HGPRT				J Med Chem 58: 827-46 (2015) Article DOI: 10.1021/jm501416t BindingDB Entry DOI: 10.7270/Q2HM5B3V
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50504220 (CHEMBL4454497) Show SMILES Nc1nc2n(CC[S+]([O-])CCP([O-])([O-])=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C9H14N5O5PS.2Na/c10-9-12-7-6(8(15)13-9)11-5-14(7)1-3-21(19)4-2-20(16,17)18;;/h5H,1-4H2,(H2,16,17,18)(H3,10,12,13,15);;/q;2*+1/p-2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human HGPRT using Prib-PP as substrate by Hanes-plot based method				Eur J Med Chem 183: (2019) Article DOI: 10.1016/j.ejmech.2019.111667 BindingDB Entry DOI: 10.7270/Q2JS9TPT
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50268140 (CHEMBL4061954) Show SMILES [Na+].[Na+].[Na+].[Na+].Nc1nc2n(CC(COCCP([O-])([O-])=O)COCCP([O-])([O-])=O)c(Br)nc2c(=O)[nH]1 Show InChI InChI=1S/C13H22BrN5O9P2/c14-12-16-9-10(17-13(15)18-11(9)20)19(12)5-8(6-27-1-3-29(21,22)23)7-28-2-4-30(24,25)26/h8H,1-7H2,(H2,21,22,23)(H2,24,25,26)(H3,15,17,18,20)/p-4	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nám. 2, CZ-16610 Prague 6, Czech Republic. Curated by ChEMBL					Assay Description Inhibition of N-terminal hexa-histidine-tagged human HGPRT using PRib-PP as substrate in presence of guanine by Hanes plot analysis				Bioorg Med Chem 25: 4008-4030 (2017) Article DOI: 10.1016/j.bmc.2017.05.048 BindingDB Entry DOI: 10.7270/Q2NS0XCJ
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50268154 (CHEMBL4090466) Show SMILES [Na+].[Na+].[Na+].[Na+].Nc1nc2n(cnc2c(=O)[nH]1)C(COCCP([O-])([O-])=O)COCCP([O-])([O-])=O Show InChI InChI=1S/C12H21N5O9P2/c13-12-15-10-9(11(18)16-12)14-7-17(10)8(5-25-1-3-27(19,20)21)6-26-2-4-28(22,23)24/h7-8H,1-6H2,(H2,19,20,21)(H2,22,23,24)(H3,13,15,16,18)/p-4	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nám. 2, CZ-16610 Prague 6, Czech Republic. Curated by ChEMBL					Assay Description Inhibition of N-terminal hexa-histidine-tagged human HGPRT using PRib-PP as substrate in presence of guanine by Hanes plot analysis				Bioorg Med Chem 25: 4008-4030 (2017) Article DOI: 10.1016/j.bmc.2017.05.048 BindingDB Entry DOI: 10.7270/Q2NS0XCJ
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50059911 (CHEMBL3394314) Show SMILES Nc1nc2n(CCN(CCCCP(O)(O)=O)CCP(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C13H24N6O7P2/c14-13-16-11-10(12(20)17-13)15-9-19(11)5-4-18(6-8-28(24,25)26)3-1-2-7-27(21,22)23/h9H,1-8H2,(H2,21,22,23)(H2,24,25,26)(H3,14,16,17,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of human HGPRT				J Med Chem 58: 827-46 (2015) Article DOI: 10.1021/jm501416t BindingDB Entry DOI: 10.7270/Q2HM5B3V
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50504218 (CHEMBL4437088) Show SMILES Nc1nc2n(CCSCCP([O-])([O-])=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C9H14N5O4PS/c10-9-12-7-6(8(15)13-9)11-5-14(7)1-3-20-4-2-19(16,17)18/h5H,1-4H2,(H2,16,17,18)(H3,10,12,13,15)/p-2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human HGPRT using Prib-PP as substrate by Hanes-plot based method				Eur J Med Chem 183: (2019) Article DOI: 10.1016/j.ejmech.2019.111667 BindingDB Entry DOI: 10.7270/Q2JS9TPT
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50258942 (CHEMBL4064903) Show SMILES [Na+].[Na+].[Na+].[Na+].Nc1nc2n(CC(COCCP([O-])([O-])=O)OCCP([O-])([O-])=O)c(Br)nc2c(=O)[nH]1 Show InChI InChI=1S/C12H20BrN5O9P2.4Na/c13-11-15-8-9(16-12(14)17-10(8)19)18(11)5-7(27-2-4-29(23,24)25)6-26-1-3-28(20,21)22;;;;/h7H,1-6H2,(H2,20,21,22)(H2,23,24,25)(H3,14,16,17,19);;;;/q;4*+1/p-4	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human HGPRT using PRib-PP as the substrate by spectrophotometric method				J Med Chem 60: 7539-7554 (2017) Article DOI: 10.1021/acs.jmedchem.7b00926 BindingDB Entry DOI: 10.7270/Q2J968T1
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50569743 (CHEMBL4857499) Show SMILES [O-]P([O-])(=O)CCN1CCN(CCP([O-])([O-])=O)C(Cn2cnc3c2nc[nH]c3=O)C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human HGPRT using PRib-PP as substrate by Hanes-plot based method				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113416 BindingDB Entry DOI: 10.7270/Q2T43XWD
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50427808 (CHEMBL2325754) Show SMILES Nc1nc2n(CC(COCCP(O)(O)=O)OCCP(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C12H21N5O9P2/c13-12-15-10-9(11(18)16-12)14-7-17(10)5-8(26-2-4-28(22,23)24)6-25-1-3-27(19,20)21/h7-8H,1-6H2,(H2,19,20,21)(H2,22,23,24)(H3,13,15,16,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human HGPRT using PRib-PP as the substrate by spectrophotometric method				J Med Chem 60: 7539-7554 (2017) Article DOI: 10.1021/acs.jmedchem.7b00926 BindingDB Entry DOI: 10.7270/Q2J968T1
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50111505 (CHEMBL3604955) Show SMILES Nc1nc2n(CCN(CCP(O)(O)=O)CC(O)CO)cnc2c(=O)[nH]1 Show InChI InChI=1S/C12H21N6O6P/c13-12-15-10-9(11(21)16-12)14-7-18(10)2-1-17(5-8(20)6-19)3-4-25(22,23)24/h7-8,19-20H,1-6H2,(H2,22,23,24)(H3,13,15,16,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of human HGPRT by spectrophotometric assay				Bioorg Med Chem 23: 5502-10 (2015) Article DOI: 10.1016/j.bmc.2015.07.038 BindingDB Entry DOI: 10.7270/Q2N58P4B
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50427808 (CHEMBL2325754) Show SMILES Nc1nc2n(CC(COCCP(O)(O)=O)OCCP(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C12H21N5O9P2/c13-12-15-10-9(11(18)16-12)14-7-17(10)5-8(26-2-4-28(22,23)24)6-25-1-3-27(19,20)21/h7-8H,1-6H2,(H2,19,20,21)(H2,22,23,24)(H3,13,15,16,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of human N-terminal hexahistidine-tagged HGPRT				J Med Chem 56: 2513-26 (2013) Article DOI: 10.1021/jm301893b BindingDB Entry DOI: 10.7270/Q2MW2JGT
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50089443 (CHEMBL3578109) Show SMILES OP(O)(=O)CCOCC(Cn1cnc2c1nc[nH]c2=O)OCCP(O)(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human HGPRT using PRib-PP as the substrate by spectrophotometric method				J Med Chem 60: 7539-7554 (2017) Article DOI: 10.1021/acs.jmedchem.7b00926 BindingDB Entry DOI: 10.7270/Q2J968T1
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50268138 (CHEMBL4066860) Show SMILES [Na+].[Na+].[Na+].[Na+].Nc1nc2n(CC(COCCP([O-])([O-])=O)COCCP([O-])([O-])=O)ccc2c(=O)[nH]1 Show InChI InChI=1S/C14H24N4O9P2/c15-14-16-12-11(13(19)17-14)1-2-18(12)7-10(8-26-3-5-28(20,21)22)9-27-4-6-29(23,24)25/h1-2,10H,3-9H2,(H2,20,21,22)(H2,23,24,25)(H3,15,16,17,19)/p-4	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nám. 2, CZ-16610 Prague 6, Czech Republic. Curated by ChEMBL					Assay Description Inhibition of N-terminal hexa-histidine-tagged human HGPRT using PRib-PP as substrate in presence of guanine by Hanes plot analysis				Bioorg Med Chem 25: 4008-4030 (2017) Article DOI: 10.1016/j.bmc.2017.05.048 BindingDB Entry DOI: 10.7270/Q2NS0XCJ
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50427809 (CHEMBL2325753) Show SMILES OP(O)(=O)COCC(COCP(O)(O)=O)Cn1cnc2c1nc[nH]c2=O Show InChI InChI=1S/C11H18N4O9P2/c16-11-9-10(12-4-13-11)15(5-14-9)1-8(2-23-6-25(17,18)19)3-24-7-26(20,21)22/h4-5,8H,1-3,6-7H2,(H,12,13,16)(H2,17,18,19)(H2,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of human N-terminal hexahistidine-tagged HGPRT				J Med Chem 56: 2513-26 (2013) Article DOI: 10.1021/jm301893b BindingDB Entry DOI: 10.7270/Q2MW2JGT
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50059912 (CHEMBL3394313) Show SMILES OP(O)(=O)CCOCCN(CCn1cnc2c1nc[nH]c2=O)CCP(O)(O)=O Show InChI InChI=1S/C13H23N5O8P2/c19-13-11-12(14-9-15-13)18(10-16-11)2-1-17(4-7-27(20,21)22)3-5-26-6-8-28(23,24)25/h9-10H,1-8H2,(H,14,15,19)(H2,20,21,22)(H2,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of human HGPRT				J Med Chem 58: 827-46 (2015) Article DOI: 10.1021/jm501416t BindingDB Entry DOI: 10.7270/Q2HM5B3V
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50059912 (CHEMBL3394313) Show SMILES OP(O)(=O)CCOCCN(CCn1cnc2c1nc[nH]c2=O)CCP(O)(O)=O Show InChI InChI=1S/C13H23N5O8P2/c19-13-11-12(14-9-15-13)18(10-16-11)2-1-17(4-7-27(20,21)22)3-5-26-6-8-28(23,24)25/h9-10H,1-8H2,(H,14,15,19)(H2,20,21,22)(H2,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human HGPRT using PRib-PP as substrate by Hanes-plot based method				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113416 BindingDB Entry DOI: 10.7270/Q2T43XWD
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50427809 (CHEMBL2325753) Show SMILES OP(O)(=O)COCC(COCP(O)(O)=O)Cn1cnc2c1nc[nH]c2=O Show InChI InChI=1S/C11H18N4O9P2/c16-11-9-10(12-4-13-11)15(5-14-9)1-8(2-23-6-25(17,18)19)3-24-7-26(20,21)22/h4-5,8H,1-3,6-7H2,(H,12,13,16)(H2,17,18,19)(H2,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human HGPRT using PRib-PP as the substrate by spectrophotometric method				J Med Chem 60: 7539-7554 (2017) Article DOI: 10.1021/acs.jmedchem.7b00926 BindingDB Entry DOI: 10.7270/Q2J968T1
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50504225 (CHEMBL4546549) Show SMILES Nc1nc2n(CCCSCP([O-])([O-])=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C9H14N5O4PS/c10-9-12-7-6(8(15)13-9)11-4-14(7)2-1-3-20-5-19(16,17)18/h4H,1-3,5H2,(H2,16,17,18)(H3,10,12,13,15)/p-2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human HGPRT using Prib-PP as substrate by Hanes-plot based method				Eur J Med Chem 183: (2019) Article DOI: 10.1016/j.ejmech.2019.111667 BindingDB Entry DOI: 10.7270/Q2JS9TPT
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50268141 (CHEMBL4071268) Show SMILES [Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)CCOCC(COCCP([O-])([O-])=O)Cn1cnc2c1nc[nH]c2=O Show InChI InChI=1S/C13H22N4O9P2/c18-13-11-12(14-8-15-13)17(9-16-11)5-10(6-25-1-3-27(19,20)21)7-26-2-4-28(22,23)24/h8-10H,1-7H2,(H,14,15,18)(H2,19,20,21)(H2,22,23,24)/p-4	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nám. 2, CZ-16610 Prague 6, Czech Republic. Curated by ChEMBL					Assay Description Inhibition of N-terminal hexa-histidine-tagged human HGPRT using PRib-PP as substrate in presence of guanine by Hanes plot analysis				Bioorg Med Chem 25: 4008-4030 (2017) Article DOI: 10.1016/j.bmc.2017.05.048 BindingDB Entry DOI: 10.7270/Q2NS0XCJ
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50258939 (CHEMBL4102796) Show SMILES [Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)CCOCC(COCP([O-])([O-])=O)Cn1cnc2c1nc[nH]c2=O Show InChI InChI=1S/C12H20N4O9P2.4Na/c17-12-10-11(13-6-14-12)16(7-15-10)3-9(5-25-8-27(21,22)23)4-24-1-2-26(18,19)20;;;;/h6-7,9H,1-5,8H2,(H,13,14,17)(H2,18,19,20)(H2,21,22,23);;;;/q;4*+1/p-4	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human HGPRT using PRib-PP as the substrate by spectrophotometric method				J Med Chem 60: 7539-7554 (2017) Article DOI: 10.1021/acs.jmedchem.7b00926 BindingDB Entry DOI: 10.7270/Q2J968T1
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50111506 (CHEMBL3603852) Show SMILES Nc1nc2n(CCN(CCOCc3ccccc3)CCP(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C18H25N6O5P/c19-18-21-16-15(17(25)22-18)20-13-24(16)7-6-23(9-11-30(26,27)28)8-10-29-12-14-4-2-1-3-5-14/h1-5,13H,6-12H2,(H2,26,27,28)(H3,19,21,22,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of human HGPRT by spectrophotometric assay				Bioorg Med Chem 23: 5502-10 (2015) Article DOI: 10.1016/j.bmc.2015.07.038 BindingDB Entry DOI: 10.7270/Q2N58P4B
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM194504 (US9200020, 2) Show SMILES Nc1nc2n(CCN(CCP(O)(O)=O)CP(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C10H18N6O7P2/c11-10-13-8-7(9(17)14-10)12-5-16(8)2-1-15(6-25(21,22)23)3-4-24(18,19)20/h5H,1-4,6H2,(H2,18,19,20)(H2,21,22,23)(H3,11,13,14,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of human HGPRT by spectrophotometric assay				Bioorg Med Chem 23: 5502-10 (2015) Article DOI: 10.1016/j.bmc.2015.07.038 BindingDB Entry DOI: 10.7270/Q2N58P4B
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50392251 (CHEMBL2153490) Show SMILES OP(O)(=O)CCN(CCC#N)CCn1cnc2c1nc[nH]c2=O Show InChI InChI=1S/C12H17N6O4P/c13-2-1-3-17(6-7-23(20,21)22)4-5-18-9-16-10-11(18)14-8-15-12(10)19/h8-9H,1,3-7H2,(H,14,15,19)(H2,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of human HGPRT				J Med Chem 58: 827-46 (2015) Article DOI: 10.1021/jm501416t BindingDB Entry DOI: 10.7270/Q2HM5B3V
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50258938 (CHEMBL4083808) Show SMILES [Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)CCOCC(COCP([O-])([O-])=O)Cn1c(Br)nc2c1nc[nH]c2=O Show InChI InChI=1S/C12H19BrN4O9P2.4Na/c13-12-16-9-10(14-6-15-11(9)18)17(12)3-8(5-26-7-28(22,23)24)4-25-1-2-27(19,20)21;;;;/h6,8H,1-5,7H2,(H,14,15,18)(H2,19,20,21)(H2,22,23,24);;;;/q;4*+1/p-4	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human HGPRT using PRib-PP as the substrate by spectrophotometric method				J Med Chem 60: 7539-7554 (2017) Article DOI: 10.1021/acs.jmedchem.7b00926 BindingDB Entry DOI: 10.7270/Q2J968T1
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50268153 (CHEMBL4068620) Show SMILES [Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)CCOCC(COCCP([O-])([O-])=O)n1cnc2c1nc[nH]c2=O Show InChI InChI=1S/C12H20N4O9P2/c17-12-10-11(13-7-14-12)16(8-15-10)9(5-24-1-3-26(18,19)20)6-25-2-4-27(21,22)23/h7-9H,1-6H2,(H,13,14,17)(H2,18,19,20)(H2,21,22,23)/p-4	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nám. 2, CZ-16610 Prague 6, Czech Republic. Curated by ChEMBL					Assay Description Inhibition of N-terminal hexa-histidine-tagged human HGPRT using PRib-PP as substrate in presence of guanine by Hanes plot analysis				Bioorg Med Chem 25: 4008-4030 (2017) Article DOI: 10.1016/j.bmc.2017.05.048 BindingDB Entry DOI: 10.7270/Q2NS0XCJ
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50504219 (CHEMBL4518487) Show SMILES Nc1nc2n(CCC[S+]([O-])CP([O-])([O-])=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C9H14N5O5PS.2Na/c10-9-12-7-6(8(15)13-9)11-4-14(7)2-1-3-21(19)5-20(16,17)18;;/h4H,1-3,5H2,(H2,16,17,18)(H3,10,12,13,15);;/q;2*+1/p-2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human HGPRT using Prib-PP as substrate by Hanes-plot based method				Eur J Med Chem 183: (2019) Article DOI: 10.1016/j.ejmech.2019.111667 BindingDB Entry DOI: 10.7270/Q2JS9TPT
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50111507 (CHEMBL3604957) Show SMILES OCC(O)CN(CCn1cnc2c1nc[nH]c2=O)CCP(O)(O)=O Show InChI InChI=1S/C12H20N5O6P/c18-6-9(19)5-16(3-4-24(21,22)23)1-2-17-8-15-10-11(17)13-7-14-12(10)20/h7-9,18-19H,1-6H2,(H,13,14,20)(H2,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of human HGPRT by spectrophotometric assay				Bioorg Med Chem 23: 5502-10 (2015) Article DOI: 10.1016/j.bmc.2015.07.038 BindingDB Entry DOI: 10.7270/Q2N58P4B
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50059914 (CHEMBL3394311) Show SMILES OP(O)(=O)CCCCN(CCn1cnc2c1nc[nH]c2=O)CCP(O)(O)=O Show InChI InChI=1S/C13H23N5O7P2/c19-13-11-12(14-9-15-13)18(10-16-11)5-4-17(6-8-27(23,24)25)3-1-2-7-26(20,21)22/h9-10H,1-8H2,(H,14,15,19)(H2,20,21,22)(H2,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of human HGPRT				J Med Chem 58: 827-46 (2015) Article DOI: 10.1021/jm501416t BindingDB Entry DOI: 10.7270/Q2HM5B3V
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50268136 (CHEMBL4075237) Show SMILES [Na+].[Na+].[Na+].[Na+].Nc1nc2n(CC(COCP([O-])([O-])=O)COCP([O-])([O-])=O)c(Br)nc2c(=O)[nH]1 Show InChI InChI=1S/C11H18BrN5O9P2/c12-10-14-7-8(15-11(13)16-9(7)18)17(10)1-6(2-25-4-27(19,20)21)3-26-5-28(22,23)24/h6H,1-5H2,(H2,19,20,21)(H2,22,23,24)(H3,13,15,16,18)/p-4	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nám. 2, CZ-16610 Prague 6, Czech Republic. Curated by ChEMBL					Assay Description Inhibition of N-terminal hexa-histidine-tagged human HGPRT using PRib-PP as substrate in presence of guanine by Hanes plot analysis				Bioorg Med Chem 25: 4008-4030 (2017) Article DOI: 10.1016/j.bmc.2017.05.048 BindingDB Entry DOI: 10.7270/Q2NS0XCJ
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50504221 (CHEMBL4476051) Show SMILES [O-][S+](CCn1cnc2c1nc[nH]c2=O)CCP([O-])([O-])=O Show InChI InChI=1S/C9H13N4O5PS.2Na/c14-9-7-8(10-5-11-9)13(6-12-7)1-3-20(18)4-2-19(15,16)17;;/h5-6H,1-4H2,(H,10,11,14)(H2,15,16,17);;/q;2*+1/p-2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human HGPRT using Prib-PP as substrate by Hanes-plot based method				Eur J Med Chem 183: (2019) Article DOI: 10.1016/j.ejmech.2019.111667 BindingDB Entry DOI: 10.7270/Q2JS9TPT
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50258936 (CHEMBL4066772) Show SMILES [Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)CCOCC(COCP([O-])([O-])=O)Cn1ccc2c1nc[nH]c2=O Show InChI InChI=1S/C13H21N3O9P2.4Na/c17-13-11-1-2-16(12(11)14-8-15-13)5-10(7-25-9-27(21,22)23)6-24-3-4-26(18,19)20;;;;/h1-2,8,10H,3-7,9H2,(H,14,15,17)(H2,18,19,20)(H2,21,22,23);;;;/q;4*+1/p-4	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human HGPRT using PRib-PP as the substrate by spectrophotometric method				J Med Chem 60: 7539-7554 (2017) Article DOI: 10.1021/acs.jmedchem.7b00926 BindingDB Entry DOI: 10.7270/Q2J968T1
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50504223 (CHEMBL4435311) Show SMILES [O-]P([O-])(=O)CCSCCn1cnc2c1nc[nH]c2=O Show InChI InChI=1S/C9H13N4O4PS/c14-9-7-8(10-5-11-9)13(6-12-7)1-3-19-4-2-18(15,16)17/h5-6H,1-4H2,(H,10,11,14)(H2,15,16,17)/p-2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human HGPRT using Prib-PP as substrate by Hanes-plot based method				Eur J Med Chem 183: (2019) Article DOI: 10.1016/j.ejmech.2019.111667 BindingDB Entry DOI: 10.7270/Q2JS9TPT
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50268143 (CHEMBL4090584) Show SMILES [Na+].[Na+].[Na+].[Na+].Nc1nc2n(ccc2c(=O)[nH]1)C(COCCP([O-])([O-])=O)COCCP([O-])([O-])=O Show InChI InChI=1S/C13H22N4O9P2/c14-13-15-11-10(12(18)16-13)1-2-17(11)9(7-25-3-5-27(19,20)21)8-26-4-6-28(22,23)24/h1-2,9H,3-8H2,(H2,19,20,21)(H2,22,23,24)(H3,14,15,16,18)/p-4	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nám. 2, CZ-16610 Prague 6, Czech Republic. Curated by ChEMBL					Assay Description Inhibition of N-terminal hexa-histidine-tagged human HGPRT using PRib-PP as substrate in presence of guanine by Hanes plot analysis				Bioorg Med Chem 25: 4008-4030 (2017) Article DOI: 10.1016/j.bmc.2017.05.048 BindingDB Entry DOI: 10.7270/Q2NS0XCJ
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50569740 (CHEMBL4845693) Show SMILES Nc1nc2n(CC3CCCN(CP([O-])([O-])=O)C3)cnc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human HGPRT using PRib-PP as substrate by Hanes-plot based method				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113416 BindingDB Entry DOI: 10.7270/Q2T43XWD
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50569738 (CHEMBL4864826) Show SMILES Nc1nc2n(C[C@@H]3CCCN3CCP([O-])([O-])=O)cnc2c(=O)[nH]1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human HGPRT using PRib-PP as substrate by Hanes-plot based method				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113416 BindingDB Entry DOI: 10.7270/Q2T43XWD
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50268139 (CHEMBL4077791) Show SMILES [Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)CCOCC(COCCP([O-])([O-])=O)Cn1c(Br)nc2c1nc[nH]c2=O Show InChI InChI=1S/C13H21BrN4O9P2/c14-13-17-10-11(15-8-16-12(10)19)18(13)5-9(6-26-1-3-28(20,21)22)7-27-2-4-29(23,24)25/h8-9H,1-7H2,(H,15,16,19)(H2,20,21,22)(H2,23,24,25)/p-4	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	9.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nám. 2, CZ-16610 Prague 6, Czech Republic. Curated by ChEMBL					Assay Description Inhibition of N-terminal hexa-histidine-tagged human HGPRT using PRib-PP as substrate in presence of guanine by Hanes plot analysis				Bioorg Med Chem 25: 4008-4030 (2017) Article DOI: 10.1016/j.bmc.2017.05.048 BindingDB Entry DOI: 10.7270/Q2NS0XCJ
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50111508 (CHEMBL3604958) Show SMILES OP(O)(=O)CCN(CCn1cnc2c1nc[nH]c2=O)CP(O)(O)=O Show InChI InChI=1S/C10H17N5O7P2/c16-10-8-9(11-5-12-10)15(6-13-8)2-1-14(7-24(20,21)22)3-4-23(17,18)19/h5-6H,1-4,7H2,(H,11,12,16)(H2,17,18,19)(H2,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of human HGPRT by spectrophotometric assay				Bioorg Med Chem 23: 5502-10 (2015) Article DOI: 10.1016/j.bmc.2015.07.038 BindingDB Entry DOI: 10.7270/Q2N58P4B
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50504224 (CHEMBL4470286) Show SMILES [O-][S+](CCCn1cnc2c1nc[nH]c2=O)CP([O-])([O-])=O Show InChI InChI=1S/C9H13N4O5PS.2Na/c14-9-7-8(10-4-11-9)13(5-12-7)2-1-3-20(18)6-19(15,16)17;;/h4-5H,1-3,6H2,(H,10,11,14)(H2,15,16,17);;/q;2*+1/p-2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human HGPRT using Prib-PP as substrate by Hanes-plot based method				Eur J Med Chem 183: (2019) Article DOI: 10.1016/j.ejmech.2019.111667 BindingDB Entry DOI: 10.7270/Q2JS9TPT
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50111509 (CHEMBL3604959) Show SMILES OP(O)(=O)CCN(CCOCc1ccccc1)CCn1cnc2c1nc[nH]c2=O Show InChI InChI=1S/C18H24N5O5P/c24-18-16-17(19-13-20-18)23(14-21-16)7-6-22(9-11-29(25,26)27)8-10-28-12-15-4-2-1-3-5-15/h1-5,13-14H,6-12H2,(H,19,20,24)(H2,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of human HGPRT by spectrophotometric assay				Bioorg Med Chem 23: 5502-10 (2015) Article DOI: 10.1016/j.bmc.2015.07.038 BindingDB Entry DOI: 10.7270/Q2N58P4B
					More data for this Ligand-Target Pair

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