Compile Data Set for Download or QSAR

Found 310 hits with Last Name = 'chen' and Initial = 'rh'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50146577 (CHEMBL102311 | spirobenzoxazines analogues) Show SMILES COc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCC2(CCCC=C2)Cc2ccccc12 |c:28| Show InChI InChI=1S/C30H30N2O3/c1-35-27-12-6-4-10-25(27)28(33)31-24-15-13-22(14-16-24)29(34)32-20-19-30(17-7-2-8-18-30)21-23-9-3-5-11-26(23)32/h3-7,9-17H,2,8,18-21H2,1H3,(H,31,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description In vitro inhibitory concentration against [3H]-AVP binding to cloned human vasopressin receptor				Bioorg Med Chem Lett 14: 2987-9 (2004) Article DOI: 10.1016/j.bmcl.2004.02.103 BindingDB Entry DOI: 10.7270/Q2BK1BSD
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50225162 ((4R)-N-[2-(dimethylamino)ethyl]-1-({4-[(2-phenylbe...) Show SMILES CN(C)CCNC(=O)C1=C[C@@]2(CC1)CCN(C(=O)c1ccc(NC(=O)c3ccccc3-c3ccccc3)cc1)c1ccccc1C2 |t:8| Show InChI InChI=1S/C39H40N4O3/c1-42(2)25-23-40-36(44)31-20-21-39(27-31)22-24-43(35-15-9-6-12-30(35)26-39)38(46)29-16-18-32(19-17-29)41-37(45)34-14-8-7-13-33(34)28-10-4-3-5-11-28/h3-19,27H,20-26H2,1-2H3,(H,40,44)(H,41,45)/t39-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Displacement of [3H]-Arg-vasopressin from human recombinant vasopressin V1a receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6623-8 (2007) Article DOI: 10.1016/j.bmcl.2007.09.059 BindingDB Entry DOI: 10.7270/Q2T72H5P
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50366915 (CHEMBL1788220) Show SMILES CN(C)CCNC(=O)C1=C[C@]2(CC1)CCN(C(=O)c1ccc(NC(=O)c3ccccc3-c3ccccc3)cc1)c1ccccc1C2 |r,t:8| Show InChI InChI=1S/C39H40N4O3/c1-42(2)25-23-40-36(44)31-20-21-39(27-31)22-24-43(35-15-9-6-12-30(35)26-39)38(46)29-16-18-32(19-17-29)41-37(45)34-14-8-7-13-33(34)28-10-4-3-5-11-28/h3-19,27H,20-26H2,1-2H3,(H,40,44)(H,41,45)/t39-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity measured by inhibition of 3[H] AVP binding to cloned human vasopressin V1a receptor				Bioorg Med Chem Lett 14: 3143-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.016 BindingDB Entry DOI: 10.7270/Q2Z60PMQ
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50366914 (CHEMBL1788221) Show SMILES CN(C)CCNC(=O)C1=C[C@@]2(CC1)CCN(C(=O)c1ccc(NC(=O)c3ccccc3F)cc1)c1ccccc1C2 |r,t:8| Show InChI InChI=1S/C33H35FN4O3/c1-37(2)20-18-35-30(39)25-15-16-33(22-25)17-19-38(29-10-6-3-7-24(29)21-33)32(41)23-11-13-26(14-12-23)36-31(40)27-8-4-5-9-28(27)34/h3-14,22H,15-21H2,1-2H3,(H,35,39)(H,36,40)/t33-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity measured by inhibition of 3[H] AVP binding to cloned human vasopressin V1a receptor				Bioorg Med Chem Lett 14: 3143-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.016 BindingDB Entry DOI: 10.7270/Q2Z60PMQ
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50147223 (3'N-(2-hydroxyethyl)-1-[4-(2-fluorophenylcarboxami...) Show SMILES OCCNC(=O)C1=CC2(CC1)CCN(C(=O)c1ccc(NC(=O)c3ccccc3F)cc1)c1ccccc1C2 |t:6| Show InChI InChI=1S/C31H30FN3O4/c32-26-7-3-2-6-25(26)29(38)34-24-11-9-21(10-12-24)30(39)35-17-15-31(19-22-5-1-4-8-27(22)35)14-13-23(20-31)28(37)33-16-18-36/h1-12,20,36H,13-19H2,(H,33,37)(H,34,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity measured by inhibition of 3[H] AVP binding to cloned human vasopressin V1a receptor				Bioorg Med Chem Lett 14: 3143-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.016 BindingDB Entry DOI: 10.7270/Q2Z60PMQ
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50147220 (4-{2-[1-[4-(2-fluorophenylcarboxamido)benzoyl]spir...) Show SMILES Fc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCC2(CCC(=C2)C(=O)NCCN2CCOCC2)Cc2ccccc12 |c:26| Show InChI InChI=1S/C35H37FN4O4/c36-30-7-3-2-6-29(30)33(42)38-28-11-9-25(10-12-28)34(43)40-17-15-35(23-26-5-1-4-8-31(26)40)14-13-27(24-35)32(41)37-16-18-39-19-21-44-22-20-39/h1-12,24H,13-23H2,(H,37,41)(H,38,42)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity measured by inhibition of 3[H] AVP binding to cloned human vasopressin V1a receptor				Bioorg Med Chem Lett 14: 3143-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.016 BindingDB Entry DOI: 10.7270/Q2Z60PMQ
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50147224 (3'N-(2-dimethylaminoethyl)-1-[4-(2-phenylphenylcar...) Show SMILES CN(C)CCNC(=O)C1=CC2(CC1)CCN(C(=O)c1ccc(NC(=O)c3ccccc3-c3ccccc3)cc1)c1ccccc1C2 |t:8| Show InChI InChI=1S/C39H40N4O3/c1-42(2)25-23-40-36(44)31-20-21-39(27-31)22-24-43(35-15-9-6-12-30(35)26-39)38(46)29-16-18-32(19-17-29)41-37(45)34-14-8-7-13-33(34)28-10-4-3-5-11-28/h3-19,27H,20-26H2,1-2H3,(H,40,44)(H,41,45)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Evaluated for intracellular calcium mobilization in HEK293 cells transfected to express human vasopressin V1a receptor				Bioorg Med Chem Lett 14: 3143-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.016 BindingDB Entry DOI: 10.7270/Q2Z60PMQ
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50147227 (3'N-(3-dimethylaminopropyl)-1-[4-(5-fluoro-2-methy...) Show SMILES CN(C)CCCNC(=O)C1=CC2(CC1)CCN(C(=O)c1ccc(NC(=O)c3cc(F)ccc3C)cc1)c1ccccc1C2 |t:9| Show InChI InChI=1S/C35H39FN4O3/c1-24-9-12-28(36)21-30(24)33(42)38-29-13-10-25(11-14-29)34(43)40-20-17-35(22-26-7-4-5-8-31(26)40)16-15-27(23-35)32(41)37-18-6-19-39(2)3/h4-5,7-14,21,23H,6,15-20,22H2,1-3H3,(H,37,41)(H,38,42)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Evaluated for intracellular calcium mobilization in HEK293 cells transfected to express human vasopressin V1a receptor				Bioorg Med Chem Lett 14: 3143-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.016 BindingDB Entry DOI: 10.7270/Q2Z60PMQ
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50225163 ((4R)-1-({4-[(2-chloro-5-fluorobenzene)amido]-3-met...) Show SMILES COc1cc(ccc1NC(=O)c1cc(F)ccc1Cl)C(=O)N1CC[C@@]2(CCC(=C2)C(O)=O)Cc2ccccc12 |c:29| Show InChI InChI=1S/C30H26ClFN2O5/c1-39-26-14-18(6-9-24(26)33-27(35)22-15-21(32)7-8-23(22)31)28(36)34-13-12-30(11-10-20(17-30)29(37)38)16-19-4-2-3-5-25(19)34/h2-9,14-15,17H,10-13,16H2,1H3,(H,33,35)(H,37,38)/t30-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Displacement of [3H]-Arg-vasopressin from human recombinant vasopressin V1a receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6623-8 (2007) Article DOI: 10.1016/j.bmcl.2007.09.059 BindingDB Entry DOI: 10.7270/Q2T72H5P
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50147219 (3'N-(2-dimethylaminoethyl)-1-[4-(5-fluoro-2-methyl...) Show SMILES CN(C)CCNC(=O)C1=CC2(CC1)CCN(C(=O)c1ccc(NC(=O)c3cc(F)ccc3C)cc1)c1ccccc1C2 |t:8| Show InChI InChI=1S/C34H37FN4O3/c1-23-8-11-27(35)20-29(23)32(41)37-28-12-9-24(10-13-28)33(42)39-18-16-34(21-25-6-4-5-7-30(25)39)15-14-26(22-34)31(40)36-17-19-38(2)3/h4-13,20,22H,14-19,21H2,1-3H3,(H,36,40)(H,37,41)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity measured by inhibition of 3[H] AVP binding to cloned human vasopressin V1a receptor				Bioorg Med Chem Lett 14: 3143-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.016 BindingDB Entry DOI: 10.7270/Q2Z60PMQ
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50147224 (3'N-(2-dimethylaminoethyl)-1-[4-(2-phenylphenylcar...) Show SMILES CN(C)CCNC(=O)C1=CC2(CC1)CCN(C(=O)c1ccc(NC(=O)c3ccccc3-c3ccccc3)cc1)c1ccccc1C2 |t:8| Show InChI InChI=1S/C39H40N4O3/c1-42(2)25-23-40-36(44)31-20-21-39(27-31)22-24-43(35-15-9-6-12-30(35)26-39)38(46)29-16-18-32(19-17-29)41-37(45)34-14-8-7-13-33(34)28-10-4-3-5-11-28/h3-19,27H,20-26H2,1-2H3,(H,40,44)(H,41,45)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Evaluated for intracellular calcium mobilization in HEK293 cells transfected to express human vasopressin V1a receptor				Bioorg Med Chem Lett 14: 3143-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.016 BindingDB Entry DOI: 10.7270/Q2Z60PMQ
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50147227 (3'N-(3-dimethylaminopropyl)-1-[4-(5-fluoro-2-methy...) Show SMILES CN(C)CCCNC(=O)C1=CC2(CC1)CCN(C(=O)c1ccc(NC(=O)c3cc(F)ccc3C)cc1)c1ccccc1C2 |t:9| Show InChI InChI=1S/C35H39FN4O3/c1-24-9-12-28(36)21-30(24)33(42)38-29-13-10-25(11-14-29)34(43)40-20-17-35(22-26-7-4-5-8-31(26)40)16-15-27(23-35)32(41)37-18-6-19-39(2)3/h4-5,7-14,21,23H,6,15-20,22H2,1-3H3,(H,37,41)(H,38,42)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity measured by inhibition of 3[H] AVP binding to cloned human vasopressin V2 receptor				Bioorg Med Chem Lett 14: 3143-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.016 BindingDB Entry DOI: 10.7270/Q2Z60PMQ
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50065115 (3-chloro-4-(10,11-dihydro-5H-benzo[e]pyrrolo[1,2-a...) Show SMILES Cc1ccc(F)cc1C(=O)Nc1ccc(C(=O)N2Cc3cccn3Cc3ccccc23)c(Cl)c1 Show InChI InChI=1S/C27H21ClFN3O2/c1-17-8-9-19(29)13-23(17)26(33)30-20-10-11-22(24(28)14-20)27(34)32-16-21-6-4-12-31(21)15-18-5-2-3-7-25(18)32/h2-14H,15-16H2,1H3,(H,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Displacement of [3H]-Arg-vasopressin from human recombinant vasopressin V2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6623-8 (2007) Article DOI: 10.1016/j.bmcl.2007.09.059 BindingDB Entry DOI: 10.7270/Q2T72H5P
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Rattus norvegicus (Rat))	BDBM50366915 (CHEMBL1788220) Show SMILES CN(C)CCNC(=O)C1=C[C@]2(CC1)CCN(C(=O)c1ccc(NC(=O)c3ccccc3-c3ccccc3)cc1)c1ccccc1C2 |r,t:8| Show InChI InChI=1S/C39H40N4O3/c1-42(2)25-23-40-36(44)31-20-21-39(27-31)22-24-43(35-15-9-6-12-30(35)26-39)38(46)29-16-18-32(19-17-29)41-37(45)34-14-8-7-13-33(34)28-10-4-3-5-11-28/h3-19,27H,20-26H2,1-2H3,(H,40,44)(H,41,45)/t39-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Evaluated for binding affinity towards vasopressin V2 receptor in rat				Bioorg Med Chem Lett 14: 3143-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.016 BindingDB Entry DOI: 10.7270/Q2Z60PMQ
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50147221 (3'N-(2-hydroxyethyl)-1-[4-(2-phenylphenylcarboxami...) Show SMILES OCCNC(=O)C1=CC2(CC1)CCN(C(=O)c1ccc(NC(=O)c3ccccc3-c3ccccc3)cc1)c1ccccc1C2 |t:6| Show InChI InChI=1S/C37H35N3O4/c41-23-21-38-34(42)29-18-19-37(25-29)20-22-40(33-13-7-4-10-28(33)24-37)36(44)27-14-16-30(17-15-27)39-35(43)32-12-6-5-11-31(32)26-8-2-1-3-9-26/h1-17,25,41H,18-24H2,(H,38,42)(H,39,43)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Evaluated for intracellular calcium mobilization in HEK293 cells transfected to express human vasopressin V1a receptor				Bioorg Med Chem Lett 14: 3143-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.016 BindingDB Entry DOI: 10.7270/Q2Z60PMQ
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50147228 (3'N-(3-dimethylaminopropyl)-1-[4-(2-phenylphenylca...) Show SMILES CN(C)CCCNC(=O)C1=CC2(CC1)CCN(C(=O)c1ccc(NC(=O)c3ccccc3-c3ccccc3)cc1)c1ccccc1C2 |t:9| Show InChI InChI=1S/C40H42N4O3/c1-43(2)25-10-24-41-37(45)32-21-22-40(28-32)23-26-44(36-16-9-6-13-31(36)27-40)39(47)30-17-19-33(20-18-30)42-38(46)35-15-8-7-14-34(35)29-11-4-3-5-12-29/h3-9,11-20,28H,10,21-27H2,1-2H3,(H,41,45)(H,42,46)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity measured by inhibition of 3[H] AVP binding to cloned human vasopressin V1a receptor				Bioorg Med Chem Lett 14: 3143-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.016 BindingDB Entry DOI: 10.7270/Q2Z60PMQ
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50147221 (3'N-(2-hydroxyethyl)-1-[4-(2-phenylphenylcarboxami...) Show SMILES OCCNC(=O)C1=CC2(CC1)CCN(C(=O)c1ccc(NC(=O)c3ccccc3-c3ccccc3)cc1)c1ccccc1C2 |t:6| Show InChI InChI=1S/C37H35N3O4/c41-23-21-38-34(42)29-18-19-37(25-29)20-22-40(33-13-7-4-10-28(33)24-37)36(44)27-14-16-30(17-15-27)39-35(43)32-12-6-5-11-31(32)26-8-2-1-3-9-26/h1-17,25,41H,18-24H2,(H,38,42)(H,39,43)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity measured by inhibition of 3[H] AVP binding to cloned human vasopressin V1a receptor				Bioorg Med Chem Lett 14: 3143-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.016 BindingDB Entry DOI: 10.7270/Q2Z60PMQ
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50135417 (((R)-5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}-2...) Show SMILES OC(=O)C[C@H]1CCN(C(=O)c2ccc(NC(=O)c3ccccc3-c3ccccc3)cc2)c2ccccc2S1 Show InChI InChI=1S/C31H26N2O4S/c34-29(35)20-24-18-19-33(27-12-6-7-13-28(27)38-24)31(37)22-14-16-23(17-15-22)32-30(36)26-11-5-4-10-25(26)21-8-2-1-3-9-21/h1-17,24H,18-20H2,(H,32,36)(H,34,35)/t24-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development L.L.C. Curated by ChEMBL					Assay Description Inhibition of vasopressin induced calcium immobilization in human V1a receptor expressing cells				Bioorg Med Chem Lett 13: 4031-4 (2003) BindingDB Entry DOI: 10.7270/Q23T9GM3
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50135413 ((5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}-2,3,4...) Show SMILES OC(=O)CC1CCN(C(=O)c2ccc(NC(=O)c3ccccc3-c3ccccc3)cc2)c2ccccc2S1 Show InChI InChI=1S/C31H26N2O4S/c34-29(35)20-24-18-19-33(27-12-6-7-13-28(27)38-24)31(37)22-14-16-23(17-15-22)32-30(36)26-11-5-4-10-25(26)21-8-2-1-3-9-21/h1-17,24H,18-20H2,(H,32,36)(H,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development L.L.C. Curated by ChEMBL					Assay Description Ability to displace [3H]-arginine vasopressin in cloned human V2 receptor				Bioorg Med Chem Lett 13: 4031-4 (2003) BindingDB Entry DOI: 10.7270/Q23T9GM3
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50147230 (CHEMBL319636 | methyl 2-[1-[4-(5-fluoro-2-methylph...) Show SMILES COC(=O)CNC(=O)C1=CC2(CC1)CCN(C(=O)c1ccc(NC(=O)c3cc(F)ccc3C)cc1)c1ccccc1C2 |t:8| Show InChI InChI=1S/C33H32FN3O5/c1-21-7-10-25(34)17-27(21)31(40)36-26-11-8-22(9-12-26)32(41)37-16-15-33(18-23-5-3-4-6-28(23)37)14-13-24(19-33)30(39)35-20-29(38)42-2/h3-12,17,19H,13-16,18,20H2,1-2H3,(H,35,39)(H,36,40)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity measured by inhibition of 3[H] AVP binding to cloned human vasopressin V1a receptor				Bioorg Med Chem Lett 14: 3143-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.016 BindingDB Entry DOI: 10.7270/Q2Z60PMQ
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50147225 (3'N-(2-hexahydro-1-pyridinylethyl)-1-[4-(2-fluorop...) Show SMILES Fc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCC2(CCC(=C2)C(=O)NCCN2CCCCC2)Cc2ccccc12 |c:26| Show InChI InChI=1S/C36H39FN4O3/c37-31-10-4-3-9-30(31)34(43)39-29-14-12-26(13-15-29)35(44)41-22-18-36(24-27-8-2-5-11-32(27)41)17-16-28(25-36)33(42)38-19-23-40-20-6-1-7-21-40/h2-5,8-15,25H,1,6-7,16-24H2,(H,38,42)(H,39,43)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity measured by inhibition of 3[H] AVP binding to cloned human vasopressin V1a receptor				Bioorg Med Chem Lett 14: 3143-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.016 BindingDB Entry DOI: 10.7270/Q2Z60PMQ
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50135420 (((S)-5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}-2...) Show SMILES OC(=O)C[C@@H]1CCN(C(=O)c2ccc(NC(=O)c3ccccc3-c3ccccc3)cc2)c2ccccc2S1 Show InChI InChI=1S/C31H26N2O4S/c34-29(35)20-24-18-19-33(27-12-6-7-13-28(27)38-24)31(37)22-14-16-23(17-15-22)32-30(36)26-11-5-4-10-25(26)21-8-2-1-3-9-21/h1-17,24H,18-20H2,(H,32,36)(H,34,35)/t24-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development L.L.C. Curated by ChEMBL					Assay Description Ability to displace [3H]-arginine vasopressin in cloned human V2 receptor				Bioorg Med Chem Lett 13: 4031-4 (2003) BindingDB Entry DOI: 10.7270/Q23T9GM3
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50147226 (3'N-(2-tetrahydro-1H-1-pyrrolylethyl)-1-[4-(2-fluo...) Show SMILES Fc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCC2(CCC(=C2)C(=O)NCCN2CCCC2)Cc2ccccc12 |c:26| Show InChI InChI=1S/C35H37FN4O3/c36-30-9-3-2-8-29(30)33(42)38-28-13-11-25(12-14-28)34(43)40-21-17-35(23-26-7-1-4-10-31(26)40)16-15-27(24-35)32(41)37-18-22-39-19-5-6-20-39/h1-4,7-14,24H,5-6,15-23H2,(H,37,41)(H,38,42)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity measured by inhibition of 3[H] AVP binding to cloned human vasopressin V1a receptor				Bioorg Med Chem Lett 14: 3143-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.016 BindingDB Entry DOI: 10.7270/Q2Z60PMQ
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50147229 (3'N-(2-hexahydro-1-pyridinylethyl)-1-[4-(5-fluoro-...) Show SMILES Cc1ccc(F)cc1C(=O)Nc1ccc(cc1)C(=O)N1CCC2(CCC(=C2)C(=O)NCCN2CCCCC2)Cc2ccccc12 |c:27| Show InChI InChI=1S/C37H41FN4O3/c1-26-9-12-30(38)23-32(26)35(44)40-31-13-10-27(11-14-31)36(45)42-21-17-37(24-28-7-3-4-8-33(28)42)16-15-29(25-37)34(43)39-18-22-41-19-5-2-6-20-41/h3-4,7-14,23,25H,2,5-6,15-22,24H2,1H3,(H,39,43)(H,40,44)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity measured by inhibition of 3[H] AVP binding to cloned human V2 receptor (Compound 7o)				Bioorg Med Chem Lett 14: 3143-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.016 BindingDB Entry DOI: 10.7270/Q2Z60PMQ
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50147222 (3'N-(2-dimethylaminoethyl)-1-[4-(2-fluorophenylcar...) Show SMILES CN(C)CCNC(=O)C1=CC2(CC1)CCN(C(=O)c1ccc(NC(=O)c3ccccc3F)cc1)c1ccccc1C2 |t:8| Show InChI InChI=1S/C33H35FN4O3/c1-37(2)20-18-35-30(39)25-15-16-33(22-25)17-19-38(29-10-6-3-7-24(29)21-33)32(41)23-11-13-26(14-12-23)36-31(40)27-8-4-5-9-28(27)34/h3-14,22H,15-21H2,1-2H3,(H,35,39)(H,36,40)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Evaluated for intracellular calcium mobilization in HEK293 cells transfected to express human vasopressin V1a receptor				Bioorg Med Chem Lett 14: 3143-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.016 BindingDB Entry DOI: 10.7270/Q2Z60PMQ
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50366915 (CHEMBL1788220) Show SMILES CN(C)CCNC(=O)C1=C[C@]2(CC1)CCN(C(=O)c1ccc(NC(=O)c3ccccc3-c3ccccc3)cc1)c1ccccc1C2 |r,t:8| Show InChI InChI=1S/C39H40N4O3/c1-42(2)25-23-40-36(44)31-20-21-39(27-31)22-24-43(35-15-9-6-12-30(35)26-39)38(46)29-16-18-32(19-17-29)41-37(45)34-14-8-7-13-33(34)28-10-4-3-5-11-28/h3-19,27H,20-26H2,1-2H3,(H,40,44)(H,41,45)/t39-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Evaluated for intracellular calcium mobilization in HEK- 293 cells transfected to express human vasopressin V1a receptor (Compound 7o)				Bioorg Med Chem Lett 14: 3143-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.016 BindingDB Entry DOI: 10.7270/Q2Z60PMQ
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50225162 ((4R)-N-[2-(dimethylamino)ethyl]-1-({4-[(2-phenylbe...) Show SMILES CN(C)CCNC(=O)C1=C[C@@]2(CC1)CCN(C(=O)c1ccc(NC(=O)c3ccccc3-c3ccccc3)cc1)c1ccccc1C2 |t:8| Show InChI InChI=1S/C39H40N4O3/c1-42(2)25-23-40-36(44)31-20-21-39(27-31)22-24-43(35-15-9-6-12-30(35)26-39)38(46)29-16-18-32(19-17-29)41-37(45)34-14-8-7-13-33(34)28-10-4-3-5-11-28/h3-19,27H,20-26H2,1-2H3,(H,40,44)(H,41,45)/t39-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Displacement of [3H]-Arg-vasopressin from human recombinant vasopressin V2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6623-8 (2007) Article DOI: 10.1016/j.bmcl.2007.09.059 BindingDB Entry DOI: 10.7270/Q2T72H5P
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50225166 ((4R)-1-({4-[(2-chloro-5-fluorobenzene)amido]-3-eth...) Show SMILES CCOc1cc(ccc1NC(=O)c1cc(F)ccc1Cl)C(=O)N1CC[C@@]2(CCC(=C2)C(O)=O)Cc2ccccc12 |c:30| Show InChI InChI=1S/C31H28ClFN2O5/c1-2-40-27-15-19(7-10-25(27)34-28(36)23-16-22(33)8-9-24(23)32)29(37)35-14-13-31(12-11-21(18-31)30(38)39)17-20-5-3-4-6-26(20)35/h3-10,15-16,18H,2,11-14,17H2,1H3,(H,34,36)(H,38,39)/t31-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Displacement of [3H]-Arg-vasopressin from human recombinant vasopressin V1a receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6623-8 (2007) Article DOI: 10.1016/j.bmcl.2007.09.059 BindingDB Entry DOI: 10.7270/Q2T72H5P
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50135414 (Biphenyl-2-carboxylic acid {4-[2-(2-hydroxy-ethyl)...) Show SMILES OCCC1CCN(C(=O)c2ccc(NC(=O)c3ccccc3-c3ccccc3)cc2)c2ccccc2S1 Show InChI InChI=1S/C31H28N2O3S/c34-21-19-25-18-20-33(28-12-6-7-13-29(28)37-25)31(36)23-14-16-24(17-15-23)32-30(35)27-11-5-4-10-26(27)22-8-2-1-3-9-22/h1-17,25,34H,18-21H2,(H,32,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development L.L.C. Curated by ChEMBL					Assay Description Ability to displace [3H]-arginine vasopressin in cloned human V2 receptor				Bioorg Med Chem Lett 13: 4031-4 (2003) BindingDB Entry DOI: 10.7270/Q23T9GM3
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50146578 (CHEMBL103406 | spirobenzoxazines analogues) Show SMILES Cc1ccc(F)cc1C(=O)Nc1ccc(cc1)C(=O)N1CCC2(CCCC=C2)Cc2ccccc12 |c:28| Show InChI InChI=1S/C30H29FN2O2/c1-21-9-12-24(31)19-26(21)28(34)32-25-13-10-22(11-14-25)29(35)33-18-17-30(15-5-2-6-16-30)20-23-7-3-4-8-27(23)33/h3-5,7-15,19H,2,6,16-18,20H2,1H3,(H,32,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description In vitro inhibitory concentration against [3H]-AVP binding to cloned human vasopressin V1a receptor				Bioorg Med Chem Lett 14: 2987-9 (2004) Article DOI: 10.1016/j.bmcl.2004.02.103 BindingDB Entry DOI: 10.7270/Q2BK1BSD
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50147229 (3'N-(2-hexahydro-1-pyridinylethyl)-1-[4-(5-fluoro-...) Show SMILES Cc1ccc(F)cc1C(=O)Nc1ccc(cc1)C(=O)N1CCC2(CCC(=C2)C(=O)NCCN2CCCCC2)Cc2ccccc12 |c:27| Show InChI InChI=1S/C37H41FN4O3/c1-26-9-12-30(38)23-32(26)35(44)40-31-13-10-27(11-14-31)36(45)42-21-17-37(24-28-7-3-4-8-33(28)42)16-15-29(25-37)34(43)39-18-22-41-19-5-2-6-20-41/h3-4,7-14,23,25H,2,5-6,15-22,24H2,1H3,(H,39,43)(H,40,44)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Evaluated for accumulation of cAMP in transfected HEK293 cells expressing human V2 receptor (Compound 7o)				Bioorg Med Chem Lett 14: 3143-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.016 BindingDB Entry DOI: 10.7270/Q2Z60PMQ
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50225167 (CHEMBL250346 | N-(4-{[3'-(hydroxymethyl)-1,2,3,5-t...) Show SMILES OCC1=CC2(CC1)CCN(C(=O)c1ccc(NC(=O)c3ccccc3-c3ccccc3)cc1)c1ccccc1C2 |w:4.3,t:2| Show InChI InChI=1S/C35H32N2O3/c38-24-25-18-19-35(22-25)20-21-37(32-13-7-4-10-28(32)23-35)34(40)27-14-16-29(17-15-27)36-33(39)31-12-6-5-11-30(31)26-8-2-1-3-9-26/h1-17,22,38H,18-21,23-24H2,(H,36,39)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Displacement of [3H]-Arg-vasopressin from human recombinant vasopressin V1a receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6623-8 (2007) Article DOI: 10.1016/j.bmcl.2007.09.059 BindingDB Entry DOI: 10.7270/Q2T72H5P
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50225167 (CHEMBL250346 | N-(4-{[3'-(hydroxymethyl)-1,2,3,5-t...) Show SMILES OCC1=CC2(CC1)CCN(C(=O)c1ccc(NC(=O)c3ccccc3-c3ccccc3)cc1)c1ccccc1C2 |w:4.3,t:2| Show InChI InChI=1S/C35H32N2O3/c38-24-25-18-19-35(22-25)20-21-37(32-13-7-4-10-28(32)23-35)34(40)27-14-16-29(17-15-27)36-33(39)31-12-6-5-11-30(31)26-8-2-1-3-9-26/h1-17,22,38H,18-21,23-24H2,(H,36,39)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Antagonist activity at human vasopressin V1a receptor expressed in HEK293 cells assessed as inhibition of Arg-vasopressin-induced intracllular calciu...				Bioorg Med Chem Lett 17: 6623-8 (2007) Article DOI: 10.1016/j.bmcl.2007.09.059 BindingDB Entry DOI: 10.7270/Q2T72H5P
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50146565 (CHEMBL101157 | spirobenzoxazines analogues) Show SMILES Fc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCC2(CCCC=C2)Cc2ccccc12 |c:27| Show InChI InChI=1S/C29H27FN2O2/c30-25-10-4-3-9-24(25)27(33)31-23-14-12-21(13-15-23)28(34)32-19-18-29(16-6-1-7-17-29)20-22-8-2-5-11-26(22)32/h2-6,8-16H,1,7,17-20H2,(H,31,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description In vitro inhibitory concentration against [3H]-AVP binding to cloned human vasopressin V1a receptor				Bioorg Med Chem Lett 14: 2987-9 (2004) Article DOI: 10.1016/j.bmcl.2004.02.103 BindingDB Entry DOI: 10.7270/Q2BK1BSD
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50076666 (CHEMBL175153 | N-Hydroxy-N-{3-[1-(4-methoxy-phenyl...) Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(C)cc1)C#CC(C)N(O)C(C)=O Show InChI InChI=1S/C23H23N3O3/c1-16-5-8-19(9-6-16)23-15-20(10-7-17(2)26(28)18(3)27)24-25(23)21-11-13-22(29-4)14-12-21/h5-6,8-9,11-15,17,28H,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against Cyclooxygenase (COX) using broken rat barophilic leukemia cells (RBL-1)				Bioorg Med Chem Lett 9: 979-84 (1999) BindingDB Entry DOI: 10.7270/Q2Z31XV3
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50147230 (CHEMBL319636 | methyl 2-[1-[4-(5-fluoro-2-methylph...) Show SMILES COC(=O)CNC(=O)C1=CC2(CC1)CCN(C(=O)c1ccc(NC(=O)c3cc(F)ccc3C)cc1)c1ccccc1C2 |t:8| Show InChI InChI=1S/C33H32FN3O5/c1-21-7-10-25(34)17-27(21)31(40)36-26-11-8-22(9-12-26)32(41)37-16-15-33(18-23-5-3-4-6-28(23)37)14-13-24(19-33)30(39)35-20-29(38)42-2/h3-12,17,19H,13-16,18,20H2,1-2H3,(H,35,39)(H,36,40)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity measured by inhibition of 3[H] AVP binding to cloned human vasopressin V2 receptor				Bioorg Med Chem Lett 14: 3143-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.016 BindingDB Entry DOI: 10.7270/Q2Z60PMQ
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50147229 (3'N-(2-hexahydro-1-pyridinylethyl)-1-[4-(5-fluoro-...) Show SMILES Cc1ccc(F)cc1C(=O)Nc1ccc(cc1)C(=O)N1CCC2(CCC(=C2)C(=O)NCCN2CCCCC2)Cc2ccccc12 |c:27| Show InChI InChI=1S/C37H41FN4O3/c1-26-9-12-30(38)23-32(26)35(44)40-31-13-10-27(11-14-31)36(45)42-21-17-37(24-28-7-3-4-8-33(28)42)16-15-29(25-37)34(43)39-18-22-41-19-5-2-6-20-41/h3-4,7-14,23,25H,2,5-6,15-22,24H2,1H3,(H,39,43)(H,40,44)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity measured by inhibition of 3[H] AVP binding to cloned human vasopressin V1a receptor				Bioorg Med Chem Lett 14: 3143-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.016 BindingDB Entry DOI: 10.7270/Q2Z60PMQ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50076661 (CHEMBL177727 | N-{1-Ethyl-3-[1-(4-methoxy-phenyl)-...) Show SMILES CCC(C#Cc1cc(-c2ccc(C)cc2)n(n1)-c1ccc(OC)cc1)N(O)C(C)=O Show InChI InChI=1S/C24H25N3O3/c1-5-21(27(29)18(3)28)11-10-20-16-24(19-8-6-17(2)7-9-19)26(25-20)22-12-14-23(30-4)15-13-22/h6-9,12-16,21,29H,5H2,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against Cyclooxygenase (COX) using broken rat barophilic leukemia cells (RBL-1)				Bioorg Med Chem Lett 9: 979-84 (1999) BindingDB Entry DOI: 10.7270/Q2Z31XV3
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50146566 (CHEMBL440147 | spirobenzoxazines analogues) Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCC2(CCCC=C2)Cc2ccccc12 |c:27| Show InChI InChI=1S/C30H30N2O2/c1-22-9-3-5-11-26(22)28(33)31-25-15-13-23(14-16-25)29(34)32-20-19-30(17-7-2-8-18-30)21-24-10-4-6-12-27(24)32/h3-7,9-17H,2,8,18-21H2,1H3,(H,31,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description In vitro inhibitory concentration against [3H]-AVP binding to cloned human vasopressin V1a receptor				Bioorg Med Chem Lett 14: 2987-9 (2004) Article DOI: 10.1016/j.bmcl.2004.02.103 BindingDB Entry DOI: 10.7270/Q2BK1BSD
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50076649 (CHEMBL369848 | N-{1-methyl-3-[1-(4-methoxyphenyl)-...) Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(Cl)cc1)C#CC(C)N(O)C(N)=O Show InChI InChI=1S/C21H19ClN4O3/c1-14(26(28)21(23)27)3-8-17-13-20(15-4-6-16(22)7-5-15)25(24-17)18-9-11-19(29-2)12-10-18/h4-7,9-14,28H,1-2H3,(H2,23,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase(5-LO) using broken rat barophilic leukemia cells (RBL-1)				Bioorg Med Chem Lett 9: 979-84 (1999) BindingDB Entry DOI: 10.7270/Q2Z31XV3
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50146572 (CHEMBL100402 | spirobenzoxazines analogues) Show SMILES Nc1ccc(cc1)C(=O)Nc1ccc(cc1)C(=O)N1CCC2(CCCC=C2)Cc2ccccc12 |c:27| Show InChI InChI=1S/C29H29N3O2/c30-24-12-8-21(9-13-24)27(33)31-25-14-10-22(11-15-25)28(34)32-19-18-29(16-4-1-5-17-29)20-23-6-2-3-7-26(23)32/h2-4,6-16H,1,5,17-20,30H2,(H,31,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description In vitro inhibitory concentration against [3H]-AVP binding to cloned human vasopressin V1a receptor				Bioorg Med Chem Lett 14: 2987-9 (2004) Article DOI: 10.1016/j.bmcl.2004.02.103 BindingDB Entry DOI: 10.7270/Q2BK1BSD
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50147224 (3'N-(2-dimethylaminoethyl)-1-[4-(2-phenylphenylcar...) Show SMILES CN(C)CCNC(=O)C1=CC2(CC1)CCN(C(=O)c1ccc(NC(=O)c3ccccc3-c3ccccc3)cc1)c1ccccc1C2 |t:8| Show InChI InChI=1S/C39H40N4O3/c1-42(2)25-23-40-36(44)31-20-21-39(27-31)22-24-43(35-15-9-6-12-30(35)26-39)38(46)29-16-18-32(19-17-29)41-37(45)34-14-8-7-13-33(34)28-10-4-3-5-11-28/h3-19,27H,20-26H2,1-2H3,(H,40,44)(H,41,45)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity measured by inhibition of 3[H] AVP binding to cloned human vasopressin V2 receptor				Bioorg Med Chem Lett 14: 3143-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.016 BindingDB Entry DOI: 10.7270/Q2Z60PMQ
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50225159 ((4R)-1-({4-[(2-chloro-5-fluorobenzene)amido]-3-met...) Show SMILES COc1cc(ccc1NC(=O)c1cc(F)ccc1Cl)C(=O)N1CC[C@@]2(CCC(=C2)C(=O)NS(N)(=O)=O)Cc2ccccc12 |c:29| Show InChI InChI=1S/C30H28ClFN4O6S/c1-42-26-14-18(6-9-24(26)34-28(38)22-15-21(32)7-8-23(22)31)29(39)36-13-12-30(16-19-4-2-3-5-25(19)36)11-10-20(17-30)27(37)35-43(33,40)41/h2-9,14-15,17H,10-13,16H2,1H3,(H,34,38)(H,35,37)(H2,33,40,41)/t30-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Antagonist activity at human vasopressin V2 receptor expressed in HEK293 cells assessed as inhibition of Arg-vasopressin-induced cAMP levels				Bioorg Med Chem Lett 17: 6623-8 (2007) Article DOI: 10.1016/j.bmcl.2007.09.059 BindingDB Entry DOI: 10.7270/Q2T72H5P
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50147221 (3'N-(2-hydroxyethyl)-1-[4-(2-phenylphenylcarboxami...) Show SMILES OCCNC(=O)C1=CC2(CC1)CCN(C(=O)c1ccc(NC(=O)c3ccccc3-c3ccccc3)cc1)c1ccccc1C2 |t:6| Show InChI InChI=1S/C37H35N3O4/c41-23-21-38-34(42)29-18-19-37(25-29)20-22-40(33-13-7-4-10-28(33)24-37)36(44)27-14-16-30(17-15-27)39-35(43)32-12-6-5-11-31(32)26-8-2-1-3-9-26/h1-17,25,41H,18-24H2,(H,38,42)(H,39,43)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity measured by inhibition of 3[H] AVP binding to cloned human vasopressin V2 receptor				Bioorg Med Chem Lett 14: 3143-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.016 BindingDB Entry DOI: 10.7270/Q2Z60PMQ
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50135419 (2-(5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}-2,3...) Show SMILES OS(=O)(=O)CCC1CCN(C(=O)c2ccc(NC(=O)c3ccccc3-c3ccccc3)cc2)c2ccccc2S1 Show InChI InChI=1S/C31H28N2O5S2/c34-30(27-11-5-4-10-26(27)22-8-2-1-3-9-22)32-24-16-14-23(15-17-24)31(35)33-20-18-25(19-21-40(36,37)38)39-29-13-7-6-12-28(29)33/h1-17,25H,18-21H2,(H,32,34)(H,36,37,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development L.L.C. Curated by ChEMBL					Assay Description Ability to displace [3H]-arginine vasopressin in cloned human V2 receptor				Bioorg Med Chem Lett 13: 4031-4 (2003) BindingDB Entry DOI: 10.7270/Q23T9GM3
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50146562 (CHEMBL100893 | spirobenzoxazines analogues) Show SMILES Clc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCC2(CCCC=C2)Cc2ccccc12 |c:27| Show InChI InChI=1S/C29H27ClN2O2/c30-25-10-4-3-9-24(25)27(33)31-23-14-12-21(13-15-23)28(34)32-19-18-29(16-6-1-7-17-29)20-22-8-2-5-11-26(22)32/h2-6,8-16H,1,7,17-20H2,(H,31,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description In vitro inhibitory concentration against [3H]-AVP binding to cloned human vasopressin V1a receptor				Bioorg Med Chem Lett 14: 2987-9 (2004) Article DOI: 10.1016/j.bmcl.2004.02.103 BindingDB Entry DOI: 10.7270/Q2BK1BSD
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50225173 ((4R)-1-({4-[(2-chloro-5-fluorobenzene)amido]phenyl...) Show SMILES OC(=O)C1=C[C@@]2(CC1)CCN(C(=O)c1ccc(NC(=O)c3cc(F)ccc3Cl)cc1)c1ccccc1C2 |t:3| Show InChI InChI=1S/C29H24ClFN2O4/c30-24-10-7-21(31)15-23(24)26(34)32-22-8-5-18(6-9-22)27(35)33-14-13-29(12-11-20(17-29)28(36)37)16-19-3-1-2-4-25(19)33/h1-10,15,17H,11-14,16H2,(H,32,34)(H,36,37)/t29-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Displacement of [3H]-Arg-vasopressin from human recombinant vasopressin V1a receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6623-8 (2007) Article DOI: 10.1016/j.bmcl.2007.09.059 BindingDB Entry DOI: 10.7270/Q2T72H5P
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50225168 (1-({4-[(2-phenylbenzene)amido]phenyl}carbonyl)-1,2...) Show SMILES OC(=O)C1=CC2(CC1)CCN(C(=O)c1ccc(NC(=O)c3ccccc3-c3ccccc3)cc1)c1ccccc1C2 |w:5.4,t:3| Show InChI InChI=1S/C35H30N2O4/c38-32(30-12-6-5-11-29(30)24-8-2-1-3-9-24)36-28-16-14-25(15-17-28)33(39)37-21-20-35(19-18-27(23-35)34(40)41)22-26-10-4-7-13-31(26)37/h1-17,23H,18-22H2,(H,36,38)(H,40,41)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Displacement of [3H]-Arg-vasopressin from human recombinant vasopressin V2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6623-8 (2007) Article DOI: 10.1016/j.bmcl.2007.09.059 BindingDB Entry DOI: 10.7270/Q2T72H5P
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50135418 (3-((S)-5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}...) Show SMILES OC(=O)CC[C@H]1CCN(C(=O)c2ccc(NC(=O)c3ccccc3-c3ccccc3)cc2)c2ccccc2S1 Show InChI InChI=1S/C32H28N2O4S/c35-30(36)19-18-25-20-21-34(28-12-6-7-13-29(28)39-25)32(38)23-14-16-24(17-15-23)33-31(37)27-11-5-4-10-26(27)22-8-2-1-3-9-22/h1-17,25H,18-21H2,(H,33,37)(H,35,36)/t25-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development L.L.C. Curated by ChEMBL					Assay Description Ability to displace [3H]-arginine vasopressin in cloned human V2 receptor				Bioorg Med Chem Lett 13: 4031-4 (2003) BindingDB Entry DOI: 10.7270/Q23T9GM3
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50225172 (CHEMBL251771 | methyl 1-({4-[(2-fluorobenzene)amid...) Show SMILES COC(=O)C1=CC2(CC1)CCN(C(=O)c1ccc(NC(=O)c3ccccc3F)cc1)c1ccccc1C2 |w:6.5,t:4| Show InChI InChI=1S/C30H27FN2O4/c1-37-29(36)22-14-15-30(19-22)16-17-33(26-9-5-2-6-21(26)18-30)28(35)20-10-12-23(13-11-20)32-27(34)24-7-3-4-8-25(24)31/h2-13,19H,14-18H2,1H3,(H,32,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Displacement of [3H]-Arg-vasopressin from human recombinant vasopressin V1a receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6623-8 (2007) Article DOI: 10.1016/j.bmcl.2007.09.059 BindingDB Entry DOI: 10.7270/Q2T72H5P
					More data for this Ligand-Target Pair

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