Compile Data Set for Download or QSAR

Found 87 hits with Last Name = 'engstrom' and Initial = 'km'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50174908 (CHEMBL427367 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...) Show SMILES [O-][N+](=O)c1ccc2n(Cc3ccccc3)nc(NC3CCN(Cc4ccc5OCOc5c4)CC3)c2c1 Show InChI InChI=1S/C27H27N5O4/c33-32(34)22-7-8-24-23(15-22)27(29-31(24)17-19-4-2-1-3-5-19)28-21-10-12-30(13-11-21)16-20-6-9-25-26(14-20)36-18-35-25/h1-9,14-15,21H,10-13,16-18H2,(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human MCHr1 from neuronal IMR32 cells				Bioorg Med Chem Lett 15: 5293-7 (2005) Article DOI: 10.1016/j.bmcl.2005.08.049 BindingDB Entry DOI: 10.7270/Q2GQ6X9P
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM20722 ((1R,2R)-2-({4-[4-({[2-fluoro-5-(trifluoromethyl)ph...) Show SMILES OC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(cc1)-c1ccc(NC(=O)Nc2cc(ccc2F)C(F)(F)F)cc1 |r| Show InChI InChI=1S/C27H22F4N2O4/c28-22-13-10-18(27(29,30)31)14-23(22)33-26(37)32-19-11-8-16(9-12-19)15-4-6-17(7-5-15)24(34)20-2-1-3-21(20)25(35)36/h4-14,20-21H,1-3H2,(H,35,36)(H2,32,33,37)/t20-,21-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...				J Med Chem 51: 380-3 (2008) Article DOI: 10.1021/jm7013887 BindingDB Entry DOI: 10.7270/Q2KW5DB6
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50174921 (CHEMBL196973 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...) Show SMILES [O-][N+](=O)c1ccc2[nH]nc(NC3CCN(Cc4ccc5OCOc5c4)CC3)c2c1 Show InChI InChI=1S/C20H21N5O4/c26-25(27)15-2-3-17-16(10-15)20(23-22-17)21-14-5-7-24(8-6-14)11-13-1-4-18-19(9-13)29-12-28-18/h1-4,9-10,14H,5-8,11-12H2,(H2,21,22,23)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human MCHr1 from neuronal IMR32 cells				Bioorg Med Chem Lett 15: 5293-7 (2005) Article DOI: 10.1016/j.bmcl.2005.08.049 BindingDB Entry DOI: 10.7270/Q2GQ6X9P
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM20721 ((1R,2R)-2-{[4-(4-{[(3-chlorophenyl)carbamoyl]amino...) Show SMILES OC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(cc1)-c1ccc(NC(=O)Nc2cccc(Cl)c2)cc1 |r| Show InChI InChI=1S/C26H23ClN2O4/c27-19-3-1-4-21(15-19)29-26(33)28-20-13-11-17(12-14-20)16-7-9-18(10-8-16)24(30)22-5-2-6-23(22)25(31)32/h1,3-4,7-15,22-23H,2,5-6H2,(H,31,32)(H2,28,29,33)/t22-,23-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...				J Med Chem 51: 380-3 (2008) Article DOI: 10.1021/jm7013887 BindingDB Entry DOI: 10.7270/Q2KW5DB6
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM20716 ((1R,2R)-2-[(4-{4-[(phenylcarbamoyl)amino]phenyl}ph...) Show SMILES OC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(cc1)-c1ccc(NC(=O)Nc2ccccc2)cc1 |r| Show InChI InChI=1S/C26H24N2O4/c29-24(22-7-4-8-23(22)25(30)31)19-11-9-17(10-12-19)18-13-15-21(16-14-18)28-26(32)27-20-5-2-1-3-6-20/h1-3,5-6,9-16,22-23H,4,7-8H2,(H,30,31)(H2,27,28,32)/t22-,23-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...				J Med Chem 51: 380-3 (2008) Article DOI: 10.1021/jm7013887 BindingDB Entry DOI: 10.7270/Q2KW5DB6
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50174920 (CHEMBL199025 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...) Show SMILES Clc1ccc2n(Cc3ccncc3)nc(NC3CCN(Cc4ccc5OCOc5c4)CC3)c2c1 Show InChI InChI=1S/C26H26ClN5O2/c27-20-2-3-23-22(14-20)26(30-32(23)16-18-5-9-28-10-6-18)29-21-7-11-31(12-8-21)15-19-1-4-24-25(13-19)34-17-33-24/h1-6,9-10,13-14,21H,7-8,11-12,15-17H2,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human MCHr1 from neuronal IMR32 cells				Bioorg Med Chem Lett 15: 5293-7 (2005) Article DOI: 10.1016/j.bmcl.2005.08.049 BindingDB Entry DOI: 10.7270/Q2GQ6X9P
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM20727 ((1R,2R)-2-[(4-{4-[(2H-1,3-benzodioxol-5-ylcarbamoy...) Show SMILES OC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(cc1)-c1ccc(NC(=O)Nc2ccc3OCOc3c2)cc1 |r| Show InChI InChI=1S/C27H24N2O6/c30-25(21-2-1-3-22(21)26(31)32)18-6-4-16(5-7-18)17-8-10-19(11-9-17)28-27(33)29-20-12-13-23-24(14-20)35-15-34-23/h4-14,21-22H,1-3,15H2,(H,31,32)(H2,28,29,33)/t21-,22-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...				J Med Chem 51: 380-3 (2008) Article DOI: 10.1021/jm7013887 BindingDB Entry DOI: 10.7270/Q2KW5DB6
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50174919 (CHEMBL371222 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...) Show SMILES COc1ccc2[nH]nc(NC3CCN(Cc4ccc5OCOc5c4)CC3)c2c1 Show InChI InChI=1S/C21H24N4O3/c1-26-16-3-4-18-17(11-16)21(24-23-18)22-15-6-8-25(9-7-15)12-14-2-5-19-20(10-14)28-13-27-19/h2-5,10-11,15H,6-9,12-13H2,1H3,(H2,22,23,24)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human MCHr1 from neuronal IMR32 cells				Bioorg Med Chem Lett 15: 5293-7 (2005) Article DOI: 10.1016/j.bmcl.2005.08.049 BindingDB Entry DOI: 10.7270/Q2GQ6X9P
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM20724 ((1R,2R)-2-{[4-(4-{[(4-methoxyphenyl)carbamoyl]amin...) Show SMILES COc1ccc(NC(=O)Nc2ccc(cc2)-c2ccc(cc2)C(=O)[C@@H]2CCC[C@H]2C(O)=O)cc1 |r| Show InChI InChI=1S/C27H26N2O5/c1-34-22-15-13-21(14-16-22)29-27(33)28-20-11-9-18(10-12-20)17-5-7-19(8-6-17)25(30)23-3-2-4-24(23)26(31)32/h5-16,23-24H,2-4H2,1H3,(H,31,32)(H2,28,29,33)/t23-,24-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...				J Med Chem 51: 380-3 (2008) Article DOI: 10.1021/jm7013887 BindingDB Entry DOI: 10.7270/Q2KW5DB6
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM20718 ((1R,2R)-2-({4-[4-({[2-(trifluoromethyl)phenyl]carb...) Show SMILES OC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(cc1)-c1ccc(NC(=O)Nc2ccccc2C(F)(F)F)cc1 |r| Show InChI InChI=1S/C27H23F3N2O4/c28-27(29,30)22-6-1-2-7-23(22)32-26(36)31-19-14-12-17(13-15-19)16-8-10-18(11-9-16)24(33)20-4-3-5-21(20)25(34)35/h1-2,6-15,20-21H,3-5H2,(H,34,35)(H2,31,32,36)/t20-,21-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...				J Med Chem 51: 380-3 (2008) Article DOI: 10.1021/jm7013887 BindingDB Entry DOI: 10.7270/Q2KW5DB6
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50174913 (CHEMBL197232 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...) Show SMILES Clc1ccc2n(Cc3ccccn3)nc(NC3CCN(Cc4ccc5OCOc5c4)CC3)c2c1 Show InChI InChI=1S/C26H26ClN5O2/c27-19-5-6-23-22(14-19)26(30-32(23)16-21-3-1-2-10-28-21)29-20-8-11-31(12-9-20)15-18-4-7-24-25(13-18)34-17-33-24/h1-7,10,13-14,20H,8-9,11-12,15-17H2,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human MCHr1 from neuronal IMR32 cells				Bioorg Med Chem Lett 15: 5293-7 (2005) Article DOI: 10.1016/j.bmcl.2005.08.049 BindingDB Entry DOI: 10.7270/Q2GQ6X9P
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM20726 ((1R,2R)-2-({4-[4-({[4-(trifluoromethyl)phenyl]carb...) Show SMILES OC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(cc1)-c1ccc(NC(=O)Nc2ccc(cc2)C(F)(F)F)cc1 |r| Show InChI InChI=1S/C27H23F3N2O4/c28-27(29,30)19-10-14-21(15-11-19)32-26(36)31-20-12-8-17(9-13-20)16-4-6-18(7-5-16)24(33)22-2-1-3-23(22)25(34)35/h4-15,22-23H,1-3H2,(H,34,35)(H2,31,32,36)/t22-,23-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...				J Med Chem 51: 380-3 (2008) Article DOI: 10.1021/jm7013887 BindingDB Entry DOI: 10.7270/Q2KW5DB6
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM20719 ((1R,2R)-2-({4-[4-({[3-(trifluoromethyl)phenyl]carb...) Show SMILES OC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(cc1)-c1ccc(NC(=O)Nc2cccc(c2)C(F)(F)F)cc1 |r| Show InChI InChI=1S/C27H23F3N2O4/c28-27(29,30)19-3-1-4-21(15-19)32-26(36)31-20-13-11-17(12-14-20)16-7-9-18(10-8-16)24(33)22-5-2-6-23(22)25(34)35/h1,3-4,7-15,22-23H,2,5-6H2,(H,34,35)(H2,31,32,36)/t22-,23-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...				J Med Chem 51: 380-3 (2008) Article DOI: 10.1021/jm7013887 BindingDB Entry DOI: 10.7270/Q2KW5DB6
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM20720 ((1R,2R)-2-{[4-(4-{[(3-fluorophenyl)carbamoyl]amino...) Show SMILES OC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(cc1)-c1ccc(NC(=O)Nc2cccc(F)c2)cc1 |r| Show InChI InChI=1S/C26H23FN2O4/c27-19-3-1-4-21(15-19)29-26(33)28-20-13-11-17(12-14-20)16-7-9-18(10-8-16)24(30)22-5-2-6-23(22)25(31)32/h1,3-4,7-15,22-23H,2,5-6H2,(H,31,32)(H2,28,29,33)/t22-,23-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...				J Med Chem 51: 380-3 (2008) Article DOI: 10.1021/jm7013887 BindingDB Entry DOI: 10.7270/Q2KW5DB6
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Mus musculus (mouse))	BDBM20726 ((1R,2R)-2-({4-[4-({[4-(trifluoromethyl)phenyl]carb...) Show SMILES OC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(cc1)-c1ccc(NC(=O)Nc2ccc(cc2)C(F)(F)F)cc1 |r| Show InChI InChI=1S/C27H23F3N2O4/c28-27(29,30)19-10-14-21(15-11-19)32-26(36)31-20-12-8-17(9-13-20)16-4-6-18(7-5-16)24(33)22-2-1-3-23(22)25(34)35/h4-15,22-23H,1-3H2,(H,34,35)(H2,31,32,36)/t22-,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...				J Med Chem 51: 380-3 (2008) Article DOI: 10.1021/jm7013887 BindingDB Entry DOI: 10.7270/Q2KW5DB6
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Mus musculus (mouse))	BDBM20718 ((1R,2R)-2-({4-[4-({[2-(trifluoromethyl)phenyl]carb...) Show SMILES OC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(cc1)-c1ccc(NC(=O)Nc2ccccc2C(F)(F)F)cc1 |r| Show InChI InChI=1S/C27H23F3N2O4/c28-27(29,30)22-6-1-2-7-23(22)32-26(36)31-19-14-12-17(13-15-19)16-8-10-18(11-9-16)24(33)20-4-3-5-21(20)25(34)35/h1-2,6-15,20-21H,3-5H2,(H,34,35)(H2,31,32,36)/t20-,21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...				J Med Chem 51: 380-3 (2008) Article DOI: 10.1021/jm7013887 BindingDB Entry DOI: 10.7270/Q2KW5DB6
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Mus musculus (mouse))	BDBM20719 ((1R,2R)-2-({4-[4-({[3-(trifluoromethyl)phenyl]carb...) Show SMILES OC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(cc1)-c1ccc(NC(=O)Nc2cccc(c2)C(F)(F)F)cc1 |r| Show InChI InChI=1S/C27H23F3N2O4/c28-27(29,30)19-3-1-4-21(15-19)32-26(36)31-20-13-11-17(12-14-20)16-7-9-18(10-8-16)24(33)22-5-2-6-23(22)25(34)35/h1,3-4,7-15,22-23H,2,5-6H2,(H,34,35)(H2,31,32,36)/t22-,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...				J Med Chem 51: 380-3 (2008) Article DOI: 10.1021/jm7013887 BindingDB Entry DOI: 10.7270/Q2KW5DB6
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Mus musculus (mouse))	BDBM20721 ((1R,2R)-2-{[4-(4-{[(3-chlorophenyl)carbamoyl]amino...) Show SMILES OC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(cc1)-c1ccc(NC(=O)Nc2cccc(Cl)c2)cc1 |r| Show InChI InChI=1S/C26H23ClN2O4/c27-19-3-1-4-21(15-19)29-26(33)28-20-13-11-17(12-14-20)16-7-9-18(10-8-16)24(30)22-5-2-6-23(22)25(31)32/h1,3-4,7-15,22-23H,2,5-6H2,(H,31,32)(H2,28,29,33)/t22-,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...				J Med Chem 51: 380-3 (2008) Article DOI: 10.1021/jm7013887 BindingDB Entry DOI: 10.7270/Q2KW5DB6
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50174893 (CHEMBL197497 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...) Show SMILES Clc1ccc2n(Cc3cccnc3)nc(NC3CCN(Cc4ccc5OCOc5c4)CC3)c2c1 Show InChI InChI=1S/C26H26ClN5O2/c27-20-4-5-23-22(13-20)26(30-32(23)16-19-2-1-9-28-14-19)29-21-7-10-31(11-8-21)15-18-3-6-24-25(12-18)34-17-33-24/h1-6,9,12-14,21H,7-8,10-11,15-17H2,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human MCHr1 from neuronal IMR32 cells				Bioorg Med Chem Lett 15: 5293-7 (2005) Article DOI: 10.1016/j.bmcl.2005.08.049 BindingDB Entry DOI: 10.7270/Q2GQ6X9P
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50174895 ((1-benzo{1,3}dioxol-5-ylmethyl-piperidin-4-yl)(5-c...) Show SMILES Clc1ccc2[nH]nc(NC3CCN(Cc4ccc5OCOc5c4)CC3)c2c1 Show InChI InChI=1S/C20H21ClN4O2/c21-14-2-3-17-16(10-14)20(24-23-17)22-15-5-7-25(8-6-15)11-13-1-4-18-19(9-13)27-12-26-18/h1-4,9-10,15H,5-8,11-12H2,(H2,22,23,24)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human MCHr1 from neuronal IMR32 cells				Bioorg Med Chem Lett 15: 5293-7 (2005) Article DOI: 10.1016/j.bmcl.2005.08.049 BindingDB Entry DOI: 10.7270/Q2GQ6X9P
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50174899 ((3-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-...) Show SMILES Clc1ccc2n(nc(NC3CCN(Cc4ccc5OCOc5c4)CC3)c2c1)C(=O)c1cscn1 Show InChI InChI=1S/C24H22ClN5O3S/c25-16-2-3-20-18(10-16)23(28-30(20)24(31)19-12-34-13-26-19)27-17-5-7-29(8-6-17)11-15-1-4-21-22(9-15)33-14-32-21/h1-4,9-10,12-13,17H,5-8,11,14H2,(H,27,28)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human MCHr1 from neuronal IMR32 cells				Bioorg Med Chem Lett 15: 5293-7 (2005) Article DOI: 10.1016/j.bmcl.2005.08.049 BindingDB Entry DOI: 10.7270/Q2GQ6X9P
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50174906 ((3-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-...) Show SMILES Clc1ccc2n(nc(NC3CCN(Cc4ccc5OCOc5c4)CC3)c2c1)C(=O)c1cccnc1 Show InChI InChI=1S/C26H24ClN5O3/c27-19-4-5-22-21(13-19)25(30-32(22)26(33)18-2-1-9-28-14-18)29-20-7-10-31(11-8-20)15-17-3-6-23-24(12-17)35-16-34-23/h1-6,9,12-14,20H,7-8,10-11,15-16H2,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human MCHr1 from neuronal IMR32 cells				Bioorg Med Chem Lett 15: 5293-7 (2005) Article DOI: 10.1016/j.bmcl.2005.08.049 BindingDB Entry DOI: 10.7270/Q2GQ6X9P
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50174911 (1-(3-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-...) Show SMILES Clc1ccc2n(nc(NC3CCN(Cc4ccc5OCOc5c4)CC3)c2c1)C(=O)CN1CCOCC1 Show InChI InChI=1S/C26H30ClN5O4/c27-19-2-3-22-21(14-19)26(29-32(22)25(33)16-31-9-11-34-12-10-31)28-20-5-7-30(8-6-20)15-18-1-4-23-24(13-18)36-17-35-23/h1-4,13-14,20H,5-12,15-17H2,(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human MCHr1 from neuronal IMR32 cells				Bioorg Med Chem Lett 15: 5293-7 (2005) Article DOI: 10.1016/j.bmcl.2005.08.049 BindingDB Entry DOI: 10.7270/Q2GQ6X9P
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50174916 (5-chloro-N-(1-(naphthalen-2-ylmethyl)piperidin-4-y...) Show SMILES Clc1ccc2n(Cc3ccccn3)nc(NC3CCN(Cc4ccc5ccccc5c4)CC3)c2c1 Show InChI InChI=1S/C29H28ClN5/c30-24-10-11-28-27(18-24)29(33-35(28)20-26-7-3-4-14-31-26)32-25-12-15-34(16-13-25)19-21-8-9-22-5-1-2-6-23(22)17-21/h1-11,14,17-18,25H,12-13,15-16,19-20H2,(H,32,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human MCHr1 from neuronal IMR32 cells				Bioorg Med Chem Lett 15: 5293-7 (2005) Article DOI: 10.1016/j.bmcl.2005.08.049 BindingDB Entry DOI: 10.7270/Q2GQ6X9P
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Mus musculus (mouse))	BDBM20722 ((1R,2R)-2-({4-[4-({[2-fluoro-5-(trifluoromethyl)ph...) Show SMILES OC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(cc1)-c1ccc(NC(=O)Nc2cc(ccc2F)C(F)(F)F)cc1 |r| Show InChI InChI=1S/C27H22F4N2O4/c28-22-13-10-18(27(29,30)31)14-23(22)33-26(37)32-19-11-8-16(9-12-19)15-4-6-17(7-5-15)24(34)20-2-1-3-21(20)25(35)36/h4-14,20-21H,1-3H2,(H,35,36)(H2,32,33,37)/t20-,21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...				J Med Chem 51: 380-3 (2008) Article DOI: 10.1021/jm7013887 BindingDB Entry DOI: 10.7270/Q2KW5DB6
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Mus musculus (mouse))	BDBM20716 ((1R,2R)-2-[(4-{4-[(phenylcarbamoyl)amino]phenyl}ph...) Show SMILES OC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(cc1)-c1ccc(NC(=O)Nc2ccccc2)cc1 |r| Show InChI InChI=1S/C26H24N2O4/c29-24(22-7-4-8-23(22)25(30)31)19-11-9-17(10-12-19)18-13-15-21(16-14-18)28-26(32)27-20-5-2-1-3-6-20/h1-3,5-6,9-16,22-23H,4,7-8H2,(H,30,31)(H2,27,28,32)/t22-,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...				J Med Chem 51: 380-3 (2008) Article DOI: 10.1021/jm7013887 BindingDB Entry DOI: 10.7270/Q2KW5DB6
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Mus musculus (mouse))	BDBM20724 ((1R,2R)-2-{[4-(4-{[(4-methoxyphenyl)carbamoyl]amin...) Show SMILES COc1ccc(NC(=O)Nc2ccc(cc2)-c2ccc(cc2)C(=O)[C@@H]2CCC[C@H]2C(O)=O)cc1 |r| Show InChI InChI=1S/C27H26N2O5/c1-34-22-15-13-21(14-16-22)29-27(33)28-20-11-9-18(10-12-20)17-5-7-19(8-6-17)25(30)23-3-2-4-24(23)26(31)32/h5-16,23-24H,2-4H2,1H3,(H,31,32)(H2,28,29,33)/t23-,24-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...				J Med Chem 51: 380-3 (2008) Article DOI: 10.1021/jm7013887 BindingDB Entry DOI: 10.7270/Q2KW5DB6
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50174892 (CHEMBL381013 | N-(1-((2,3-dihydrobenzo[b][1,4]diox...) Show SMILES [O-][N+](=O)c1ccc2[nH]nc(NC3CCN(Cc4ccc5OCCOc5c4)CC3)c2c1 Show InChI InChI=1S/C21H23N5O4/c27-26(28)16-2-3-18-17(12-16)21(24-23-18)22-15-5-7-25(8-6-15)13-14-1-4-19-20(11-14)30-10-9-29-19/h1-4,11-12,15H,5-10,13H2,(H2,22,23,24)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human MCHr1 from neuronal IMR32 cells				Bioorg Med Chem Lett 15: 5293-7 (2005) Article DOI: 10.1016/j.bmcl.2005.08.049 BindingDB Entry DOI: 10.7270/Q2GQ6X9P
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50174915 (CHEMBL199222 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...) Show SMILES COc1ccc2n(C)nc(NC3CCN(Cc4ccc5OCOc5c4)CC3)c2c1 Show InChI InChI=1S/C22H26N4O3/c1-25-19-5-4-17(27-2)12-18(19)22(24-25)23-16-7-9-26(10-8-16)13-15-3-6-20-21(11-15)29-14-28-20/h3-6,11-12,16H,7-10,13-14H2,1-2H3,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human MCHr1 from neuronal IMR32 cells				Bioorg Med Chem Lett 15: 5293-7 (2005) Article DOI: 10.1016/j.bmcl.2005.08.049 BindingDB Entry DOI: 10.7270/Q2GQ6X9P
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM20725 ((1R,2R)-2-{[4-(4-{[(4-cyanophenyl)carbamoyl]amino}...) Show SMILES OC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(cc1)-c1ccc(NC(=O)Nc2ccc(cc2)C#N)cc1 |r| Show InChI InChI=1S/C27H23N3O4/c28-16-17-4-12-21(13-5-17)29-27(34)30-22-14-10-19(11-15-22)18-6-8-20(9-7-18)25(31)23-2-1-3-24(23)26(32)33/h4-15,23-24H,1-3H2,(H,32,33)(H2,29,30,34)/t23-,24-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...				J Med Chem 51: 380-3 (2008) Article DOI: 10.1021/jm7013887 BindingDB Entry DOI: 10.7270/Q2KW5DB6
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Mus musculus (mouse))	BDBM20720 ((1R,2R)-2-{[4-(4-{[(3-fluorophenyl)carbamoyl]amino...) Show SMILES OC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(cc1)-c1ccc(NC(=O)Nc2cccc(F)c2)cc1 |r| Show InChI InChI=1S/C26H23FN2O4/c27-19-3-1-4-21(15-19)29-26(33)28-20-13-11-17(12-14-20)16-7-9-18(10-8-16)24(30)22-5-2-6-23(22)25(31)32/h1,3-4,7-15,22-23H,2,5-6H2,(H,31,32)(H2,28,29,33)/t22-,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...				J Med Chem 51: 380-3 (2008) Article DOI: 10.1021/jm7013887 BindingDB Entry DOI: 10.7270/Q2KW5DB6
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50174897 (CHEMBL370576 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...) Show SMILES Clc1ccc2n(Cc3ccccc3)nc(NC3CCN(Cc4ccc5OCOc5c4)CC3)c2c1 Show InChI InChI=1S/C27H27ClN4O2/c28-21-7-8-24-23(15-21)27(30-32(24)17-19-4-2-1-3-5-19)29-22-10-12-31(13-11-22)16-20-6-9-25-26(14-20)34-18-33-25/h1-9,14-15,22H,10-13,16-18H2,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human MCHr1 from neuronal IMR32 cells				Bioorg Med Chem Lett 15: 5293-7 (2005) Article DOI: 10.1016/j.bmcl.2005.08.049 BindingDB Entry DOI: 10.7270/Q2GQ6X9P
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50174901 (5-chloro-N-(1-(naphthalen-2-ylmethyl)piperidin-4-y...) Show SMILES Clc1ccc2[nH]nc(NC3CCN(Cc4ccc5ccccc5c4)CC3)c2c1 Show InChI InChI=1S/C23H23ClN4/c24-19-7-8-22-21(14-19)23(27-26-22)25-20-9-11-28(12-10-20)15-16-5-6-17-3-1-2-4-18(17)13-16/h1-8,13-14,20H,9-12,15H2,(H2,25,26,27)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human MCHr1 from neuronal IMR32 cells				Bioorg Med Chem Lett 15: 5293-7 (2005) Article DOI: 10.1016/j.bmcl.2005.08.049 BindingDB Entry DOI: 10.7270/Q2GQ6X9P
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50174904 ((3-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-...) Show SMILES Clc1ccc2n(nc(NC3CCN(Cc4ccc5OCOc5c4)CC3)c2c1)C(=O)C1CC1 Show InChI InChI=1S/C24H25ClN4O3/c25-17-4-5-20-19(12-17)23(27-29(20)24(30)16-2-3-16)26-18-7-9-28(10-8-18)13-15-1-6-21-22(11-15)32-14-31-21/h1,4-6,11-12,16,18H,2-3,7-10,13-14H2,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human MCHr1 from neuronal IMR32 cells				Bioorg Med Chem Lett 15: 5293-7 (2005) Article DOI: 10.1016/j.bmcl.2005.08.049 BindingDB Entry DOI: 10.7270/Q2GQ6X9P
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50174909 (CHEMBL370361 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...) Show SMILES Clc1ccc2n(nc(NC3CCN(Cc4ccc5OCOc5c4)CC3)c2c1)-c1ccccc1 Show InChI InChI=1S/C26H25ClN4O2/c27-19-7-8-23-22(15-19)26(29-31(23)21-4-2-1-3-5-21)28-20-10-12-30(13-11-20)16-18-6-9-24-25(14-18)33-17-32-24/h1-9,14-15,20H,10-13,16-17H2,(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human MCHr1 from neuronal IMR32 cells				Bioorg Med Chem Lett 15: 5293-7 (2005) Article DOI: 10.1016/j.bmcl.2005.08.049 BindingDB Entry DOI: 10.7270/Q2GQ6X9P
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50174912 (CHEMBL198789 | N-(1-((1H-indazol-6-yl)methyl)piper...) Show SMILES COc1ccc2[nH]nc(NC3CCN(Cc4ccc5c[nH]nc5c4)CC3)c2c1 Show InChI InChI=1S/C21H24N6O/c1-28-17-4-5-19-18(11-17)21(26-25-19)23-16-6-8-27(9-7-16)13-14-2-3-15-12-22-24-20(15)10-14/h2-5,10-12,16H,6-9,13H2,1H3,(H,22,24)(H2,23,25,26)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human MCHr1 from neuronal IMR32 cells				Bioorg Med Chem Lett 15: 5293-7 (2005) Article DOI: 10.1016/j.bmcl.2005.08.049 BindingDB Entry DOI: 10.7270/Q2GQ6X9P
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50174914 (CHEMBL197395 | N-(1-(benzo[c][1,2,5]thiadiazol-5-y...) Show SMILES Clc1ccc2[nH]nc(NC3CCN(Cc4ccc5nsnc5c4)CC3)c2c1 Show InChI InChI=1S/C19H19ClN6S/c20-13-2-4-16-15(10-13)19(23-22-16)21-14-5-7-26(8-6-14)11-12-1-3-17-18(9-12)25-27-24-17/h1-4,9-10,14H,5-8,11H2,(H2,21,22,23)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human MCHr1 from neuronal IMR32 cells				Bioorg Med Chem Lett 15: 5293-7 (2005) Article DOI: 10.1016/j.bmcl.2005.08.049 BindingDB Entry DOI: 10.7270/Q2GQ6X9P
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50174919 (CHEMBL371222 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...) Show SMILES COc1ccc2[nH]nc(NC3CCN(Cc4ccc5OCOc5c4)CC3)c2c1 Show InChI InChI=1S/C21H24N4O3/c1-26-16-3-4-18-17(11-16)21(24-23-18)22-15-6-8-25(9-7-15)12-14-2-5-19-20(10-14)28-13-27-19/h2-5,10-11,15H,6-9,12-13H2,1H3,(H2,22,23,24)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Functional antagonism of MCH-mediated calcium release by FLIPR using human MCHr1 from neuronal IMR32 cells				Bioorg Med Chem Lett 15: 5293-7 (2005) Article DOI: 10.1016/j.bmcl.2005.08.049 BindingDB Entry DOI: 10.7270/Q2GQ6X9P
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Mus musculus (mouse))	BDBM20727 ((1R,2R)-2-[(4-{4-[(2H-1,3-benzodioxol-5-ylcarbamoy...) Show SMILES OC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(cc1)-c1ccc(NC(=O)Nc2ccc3OCOc3c2)cc1 |r| Show InChI InChI=1S/C27H24N2O6/c30-25(21-2-1-3-22(21)26(31)32)18-6-4-16(5-7-18)17-8-10-19(11-9-17)28-27(33)29-20-12-13-23-24(14-20)35-15-34-23/h4-14,21-22H,1-3,15H2,(H,31,32)(H2,28,29,33)/t21-,22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...				J Med Chem 51: 380-3 (2008) Article DOI: 10.1021/jm7013887 BindingDB Entry DOI: 10.7270/Q2KW5DB6
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50174921 (CHEMBL196973 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...) Show SMILES [O-][N+](=O)c1ccc2[nH]nc(NC3CCN(Cc4ccc5OCOc5c4)CC3)c2c1 Show InChI InChI=1S/C20H21N5O4/c26-25(27)15-2-3-17-16(10-15)20(23-22-17)21-14-5-7-24(8-6-14)11-13-1-4-18-19(9-13)29-12-28-18/h1-4,9-10,14H,5-8,11-12H2,(H2,21,22,23)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Functional antagonism of MCH-mediated calcium release by FLIPR using human MCHr1 from neuronal IMR32 cells				Bioorg Med Chem Lett 15: 5293-7 (2005) Article DOI: 10.1016/j.bmcl.2005.08.049 BindingDB Entry DOI: 10.7270/Q2GQ6X9P
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50174905 (5-chloro-N-(1-((2,3-dihydrobenzo[b][1,4]dioxin-6-y...) Show SMILES Clc1ccc2[nH]nc(NC3CCN(Cc4ccc5OCCOc5c4)CC3)c2c1 Show InChI InChI=1S/C21H23ClN4O2/c22-15-2-3-18-17(12-15)21(25-24-18)23-16-5-7-26(8-6-16)13-14-1-4-19-20(11-14)28-10-9-27-19/h1-4,11-12,16H,5-10,13H2,(H2,23,24,25)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human MCHr1 from neuronal IMR32 cells				Bioorg Med Chem Lett 15: 5293-7 (2005) Article DOI: 10.1016/j.bmcl.2005.08.049 BindingDB Entry DOI: 10.7270/Q2GQ6X9P
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM20730 ((1R,2R)-2-{[4-(3-fluoro-4-{[6-(trifluoromethoxy)-1...) Show SMILES OC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(cc1)-c1ccc(Nc2nc3ccc(OC(F)(F)F)cc3s2)c(F)c1 |r| Show InChI InChI=1S/C27H20F4N2O4S/c28-20-12-16(14-4-6-15(7-5-14)24(34)18-2-1-3-19(18)25(35)36)8-10-21(20)32-26-33-22-11-9-17(13-23(22)38-26)37-27(29,30)31/h4-13,18-19H,1-3H2,(H,32,33)(H,35,36)/t18-,19-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...				J Med Chem 51: 380-3 (2008) Article DOI: 10.1021/jm7013887 BindingDB Entry DOI: 10.7270/Q2KW5DB6
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM20728 ((1S,2S)-2-[(4-{4-[(phenylcarbamoyl)amino]phenyl}ph...) Show SMILES OC(=O)[C@H]1CCC[C@@H]1C(=O)c1ccc(cc1)-c1ccc(NC(=O)Nc2ccccc2)cc1 |r| Show InChI InChI=1S/C26H24N2O4/c29-24(22-7-4-8-23(22)25(30)31)19-11-9-17(10-12-19)18-13-15-21(16-14-18)28-26(32)27-20-5-2-1-3-6-20/h1-3,5-6,9-16,22-23H,4,7-8H2,(H,30,31)(H2,27,28,32)/t22-,23-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...				J Med Chem 51: 380-3 (2008) Article DOI: 10.1021/jm7013887 BindingDB Entry DOI: 10.7270/Q2KW5DB6
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM20729 ((1S,2R)-2-[(4-{4-[(phenylcarbamoyl)amino]phenyl}ph...) Show SMILES OC(=O)[C@H]1CCC[C@H]1C(=O)c1ccc(cc1)-c1ccc(NC(=O)Nc2ccccc2)cc1 |r| Show InChI InChI=1S/C26H24N2O4/c29-24(22-7-4-8-23(22)25(30)31)19-11-9-17(10-12-19)18-13-15-21(16-14-18)28-26(32)27-20-5-2-1-3-6-20/h1-3,5-6,9-16,22-23H,4,7-8H2,(H,30,31)(H2,27,28,32)/t22-,23+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...				J Med Chem 51: 380-3 (2008) Article DOI: 10.1021/jm7013887 BindingDB Entry DOI: 10.7270/Q2KW5DB6
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50174894 (CHEMBL197283 | N-(1-(3,4-dimethylbenzyl)piperidin-...) Show SMILES Cc1ccc(CN2CCC(CC2)Nc2[nH]nc3ccc(Cl)cc23)cc1C Show InChI InChI=1S/C21H25ClN4/c1-14-3-4-16(11-15(14)2)13-26-9-7-18(8-10-26)23-21-19-12-17(22)5-6-20(19)24-25-21/h3-6,11-12,18H,7-10,13H2,1-2H3,(H2,23,24,25)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human MCHr1 from neuronal IMR32 cells				Bioorg Med Chem Lett 15: 5293-7 (2005) Article DOI: 10.1016/j.bmcl.2005.08.049 BindingDB Entry DOI: 10.7270/Q2GQ6X9P
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50174896 (CHEMBL196972 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...) Show SMILES Cc1ccc2[nH]nc(NC3CCN(Cc4ccc5OCOc5c4)CC3)c2c1 Show InChI InChI=1S/C21H24N4O2/c1-14-2-4-18-17(10-14)21(24-23-18)22-16-6-8-25(9-7-16)12-15-3-5-19-20(11-15)27-13-26-19/h2-5,10-11,16H,6-9,12-13H2,1H3,(H2,22,23,24)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human MCHr1 from neuronal IMR32 cells				Bioorg Med Chem Lett 15: 5293-7 (2005) Article DOI: 10.1016/j.bmcl.2005.08.049 BindingDB Entry DOI: 10.7270/Q2GQ6X9P
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50174900 (CHEMBL197281 | N-(1-(3-methoxybenzyl)piperidin-4-y...) Show SMILES COc1cccc(CN2CCC(CC2)Nc2[nH]nc3ccc(Cl)cc23)c1 Show InChI InChI=1S/C20H23ClN4O/c1-26-17-4-2-3-14(11-17)13-25-9-7-16(8-10-25)22-20-18-12-15(21)5-6-19(18)23-24-20/h2-6,11-12,16H,7-10,13H2,1H3,(H2,22,23,24)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human MCHr1 from neuronal IMR32 cells				Bioorg Med Chem Lett 15: 5293-7 (2005) Article DOI: 10.1016/j.bmcl.2005.08.049 BindingDB Entry DOI: 10.7270/Q2GQ6X9P
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50174915 (CHEMBL199222 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...) Show SMILES COc1ccc2n(C)nc(NC3CCN(Cc4ccc5OCOc5c4)CC3)c2c1 Show InChI InChI=1S/C22H26N4O3/c1-25-19-5-4-17(27-2)12-18(19)22(24-25)23-16-7-9-26(10-8-16)13-15-3-6-20-21(11-15)29-14-28-20/h3-6,11-12,16H,7-10,13-14H2,1-2H3,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Functional antagonism of MCH-mediated calcium release by FLIPR using human MCHr1 from neuronal IMR32 cells				Bioorg Med Chem Lett 15: 5293-7 (2005) Article DOI: 10.1016/j.bmcl.2005.08.049 BindingDB Entry DOI: 10.7270/Q2GQ6X9P
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50174903 (CHEMBL370360 | N-(1-(4-chlorobenzyl)piperidin-4-yl...) Show SMILES Clc1ccc(CN2CCC(CC2)Nc2[nH]nc3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C19H20Cl2N4/c20-14-3-1-13(2-4-14)12-25-9-7-16(8-10-25)22-19-17-11-15(21)5-6-18(17)23-24-19/h1-6,11,16H,7-10,12H2,(H2,22,23,24)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human MCHr1 from neuronal IMR32 cells				Bioorg Med Chem Lett 15: 5293-7 (2005) Article DOI: 10.1016/j.bmcl.2005.08.049 BindingDB Entry DOI: 10.7270/Q2GQ6X9P
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Mus musculus (mouse))	BDBM20730 ((1R,2R)-2-{[4-(3-fluoro-4-{[6-(trifluoromethoxy)-1...) Show SMILES OC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(cc1)-c1ccc(Nc2nc3ccc(OC(F)(F)F)cc3s2)c(F)c1 |r| Show InChI InChI=1S/C27H20F4N2O4S/c28-20-12-16(14-4-6-15(7-5-14)24(34)18-2-1-3-19(18)25(35)36)8-10-21(20)32-26-33-22-11-9-17(13-23(22)38-26)37-27(29,30)31/h4-13,18-19H,1-3H2,(H,32,33)(H,35,36)/t18-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	207	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...				J Med Chem 51: 380-3 (2008) Article DOI: 10.1021/jm7013887 BindingDB Entry DOI: 10.7270/Q2KW5DB6
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 87 total )  |  Next  |  Last  >>

Jump to: