Compile Data Set for Download or QSAR

Found 268 hits with Last Name = 'fujio' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50218398 (CHEMBL1907861) Show SMILES [H][C@@]1(CCN(CCc2ccc(F)cc2)C1)NC(=O)C12CC3([H])CC([H])(CC([H])(C3)C1)C2 |r,TLB:28:20:30:29.26.25,28:26:30:19.20.22,22:23:29:19.20.28,THB:22:20:29:30.23.25| Show InChI InChI=1S/C23H31FN2O/c24-20-3-1-16(2-4-20)5-7-26-8-6-21(15-26)25-22(27)23-12-17-9-18(13-23)11-19(10-17)14-23/h1-4,17-19,21H,5-15H2,(H,25,27)/t17?,18?,19?,21-,23?/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	0.0900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 2 receptor from striata wistar rats by [3H]ketanserin displacement.				Bioorg Med Chem Lett 10: 2457-61 (2001) BindingDB Entry DOI: 10.7270/Q2VT1SN2
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50201292 (7,8-dichloro-N,N-dimethyl-3-((2-(tetrahydro-2H-pyr...) Show SMILES CN(C)C1(CNCCC2CCOCC2)COc2cc(Cl)c(Cl)cc2OC1 Show InChI InChI=1S/C19H28Cl2N2O3/c1-23(2)19(11-22-6-3-14-4-7-24-8-5-14)12-25-17-9-15(20)16(21)10-18(17)26-13-19/h9-10,14,22H,3-8,11-13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells				Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50218392 (CHEMBL79277) Show SMILES Fc1ccccc1CCN1CCC(C1)NC(=O)C12CC3CC(CC(C3)C1)C2 |TLB:24:23:26:18.19.20,24:19:26:25.23.22,THB:22:23:18:26.21.20,22:21:18:25.23.24| Show InChI InChI=1S/C23H31FN2O/c24-21-4-2-1-3-19(21)5-7-26-8-6-20(15-26)25-22(27)23-12-16-9-17(13-23)11-18(10-16)14-23/h1-4,16-18,20H,5-15H2,(H,25,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	0.140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 2 receptor from striata wistar rats by [3H]ketanserin displacement.				Bioorg Med Chem Lett 10: 2457-61 (2001) BindingDB Entry DOI: 10.7270/Q2VT1SN2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50218388 (CHEMBL78986) Show SMILES O=C(N[C@@H]1CCN(CCc2ccccc2)C1)C12CC3CC(CC(C3)C1)C2 |TLB:23:22:25:17.18.19,23:18:25:24.22.21,THB:21:22:17:25.20.19,21:20:17:24.22.23| Show InChI InChI=1S/C23H32N2O/c26-22(23-13-18-10-19(14-23)12-20(11-18)15-23)24-21-7-9-25(16-21)8-6-17-4-2-1-3-5-17/h1-5,18-21H,6-16H2,(H,24,26)/t18?,19?,20?,21-,23?/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 1A receptor from striata of wistar rats by [3H]- 8-OH -DPAT displacement.				Bioorg Med Chem Lett 10: 2457-61 (2001) BindingDB Entry DOI: 10.7270/Q2VT1SN2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50218397 (CHEMBL83611) Show SMILES O=C(NC1CCN(CCCc2ccccc2)C1)C12CC3CC(CC(C3)C1)C2 |TLB:24:23:26:18.19.20,24:19:26:25.23.22,THB:22:23:18:26.21.20,22:21:18:25.23.24| Show InChI InChI=1S/C24H34N2O/c27-23(24-14-19-11-20(15-24)13-21(12-19)16-24)25-22-8-10-26(17-22)9-4-7-18-5-2-1-3-6-18/h1-3,5-6,19-22H,4,7-17H2,(H,25,27)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 1A receptor from striata of wistar rats by [3H]- 8-OH -DPAT displacement.				Bioorg Med Chem Lett 10: 2457-61 (2001) BindingDB Entry DOI: 10.7270/Q2VT1SN2
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50201292 (7,8-dichloro-N,N-dimethyl-3-((2-(tetrahydro-2H-pyr...) Show SMILES CN(C)C1(CNCCC2CCOCC2)COc2cc(Cl)c(Cl)cc2OC1 Show InChI InChI=1S/C19H28Cl2N2O3/c1-23(2)19(11-22-6-3-14-4-7-24-8-5-14)12-25-17-9-15(20)16(21)10-18(17)26-13-19/h9-10,14,22H,3-8,11-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells				Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50218396 (CHEMBL315259) Show SMILES O=C(N[C@H]1CCN(CCc2ccccc2)C1)C12CC3CC(CC(C3)C1)C2 |TLB:23:22:25:17.18.19,23:18:25:24.22.21,THB:21:22:17:25.20.19,21:20:17:24.22.23| Show InChI InChI=1S/C23H32N2O/c26-22(23-13-18-10-19(14-23)12-20(11-18)15-23)24-21-7-9-25(16-21)8-6-17-4-2-1-3-5-17/h1-5,18-21H,6-16H2,(H,24,26)/t18?,19?,20?,21-,23?/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	0.240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 2 receptor from striata wistar rats by [3H]ketanserin displacement.				Bioorg Med Chem Lett 10: 2457-61 (2001) BindingDB Entry DOI: 10.7270/Q2VT1SN2
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50218397 (CHEMBL83611) Show SMILES O=C(NC1CCN(CCCc2ccccc2)C1)C12CC3CC(CC(C3)C1)C2 |TLB:24:23:26:18.19.20,24:19:26:25.23.22,THB:22:23:18:26.21.20,22:21:18:25.23.24| Show InChI InChI=1S/C24H34N2O/c27-23(24-14-19-11-20(15-24)13-21(12-19)16-24)25-22-8-10-26(17-22)9-4-7-18-5-2-1-3-6-18/h1-3,5-6,19-22H,4,7-17H2,(H,25,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 2 receptor from striata wistar rats by [3H]ketanserin displacement.				Bioorg Med Chem Lett 10: 2457-61 (2001) BindingDB Entry DOI: 10.7270/Q2VT1SN2
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50218399 (CHEMBL79643) Show SMILES Clc1ccc(CCN2CCC(C2)NC(=O)C23CC4CC(CC(C4)C2)C3)cc1 |TLB:22:21:24:16.17.18,22:17:24:23.21.20,THB:20:21:16:24.19.18,20:19:16:23.21.22| Show InChI InChI=1S/C23H31ClN2O/c24-20-3-1-16(2-4-20)5-7-26-8-6-21(15-26)25-22(27)23-12-17-9-18(13-23)11-19(10-17)14-23/h1-4,17-19,21H,5-15H2,(H,25,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	0.440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 2 receptor from striata wistar rats by [3H]ketanserin displacement.				Bioorg Med Chem Lett 10: 2457-61 (2001) BindingDB Entry DOI: 10.7270/Q2VT1SN2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM21393 (7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...) Show SMILES CCCN(CCC)C1CCc2cccc(O)c2C1 Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	0.470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from rat striata 5-hydroxytryptamine 1A receptor				Bioorg Med Chem Lett 10: 509-12 (2000) BindingDB Entry DOI: 10.7270/Q24Q7T7T
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50086855 (CHEMBL82884 | Cyclohexanecarboxylic acid ((S)-1-ph...) Show SMILES O=C(NC[C@@H]1CCCN1CCc1ccccc1)C1CCCCC1 Show InChI InChI=1S/C20H30N2O/c23-20(18-10-5-2-6-11-18)21-16-19-12-7-14-22(19)15-13-17-8-3-1-4-9-17/h1,3-4,8-9,18-19H,2,5-7,10-16H2,(H,21,23)/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 1A receptor from striata of wistar rats by [3H]- 8-OH -DPAT displacement.				Bioorg Med Chem Lett 10: 2457-61 (2001) BindingDB Entry DOI: 10.7270/Q2VT1SN2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50086855 (CHEMBL82884 | Cyclohexanecarboxylic acid ((S)-1-ph...) Show SMILES O=C(NC[C@@H]1CCCN1CCc1ccccc1)C1CCCCC1 Show InChI InChI=1S/C20H30N2O/c23-20(18-10-5-2-6-11-18)21-16-19-12-7-14-22(19)15-13-17-8-3-1-4-9-17/h1,3-4,8-9,18-19H,2,5-7,10-16H2,(H,21,23)/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from rat striata 5-hydroxytryptamine 1A receptor				Bioorg Med Chem Lett 10: 509-12 (2000) BindingDB Entry DOI: 10.7270/Q24Q7T7T
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50218400 (CHEMBL1907669) Show SMILES [H][C@]1(CCN(CCc2ccc(F)cc2)C1)NC(=O)C12CC3([H])CC([H])(CC([H])(C3)C1)C2 |r,TLB:28:20:30:29.26.25,28:26:30:19.20.22,22:23:29:19.20.28,THB:22:20:29:30.23.25| Show InChI InChI=1S/C23H31FN2O/c24-20-3-1-16(2-4-20)5-7-26-8-6-21(15-26)25-22(27)23-12-17-9-18(13-23)11-19(10-17)14-23/h1-4,17-19,21H,5-15H2,(H,25,27)/t17?,18?,19?,21-,23?/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.530	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 1A receptor from striata of wistar rats by [3H]- 8-OH -DPAT displacement.				Bioorg Med Chem Lett 10: 2457-61 (2001) BindingDB Entry DOI: 10.7270/Q2VT1SN2
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50218391 (CHEMBL79528) Show SMILES Fc1cccc(CCN2CCC(C2)NC(=O)C23CC4CC(CC(C4)C2)C3)c1 |TLB:23:22:25:17.18.19,23:18:25:24.22.21,THB:21:22:17:25.20.19,21:20:17:24.22.23| Show InChI InChI=1S/C23H31FN2O/c24-20-3-1-2-16(11-20)4-6-26-7-5-21(15-26)25-22(27)23-12-17-8-18(13-23)10-19(9-17)14-23/h1-3,11,17-19,21H,4-10,12-15H2,(H,25,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	0.550	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 2 receptor from striata wistar rats by [3H]ketanserin displacement.				Bioorg Med Chem Lett 10: 2457-61 (2001) BindingDB Entry DOI: 10.7270/Q2VT1SN2
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50201280 (CHEMBL394137 | {3-[(2-adamantan-1-yl-ethylamino)-m...) Show SMILES CN(C)C1(CNCCC23CC4CC(CC(C4)C2)C3)COc2ccccc2OC1 |TLB:7:8:11.10.15:13,THB:9:10:13:17.8.16,9:8:11.10.15:13,7:8:11:15.14.13,16:8:11:15.14.13,16:14:11:17.9.8| Show InChI InChI=1S/C24H36N2O2/c1-26(2)24(16-27-21-5-3-4-6-22(21)28-17-24)15-25-8-7-23-12-18-9-19(13-23)11-20(10-18)14-23/h3-6,18-20,25H,7-17H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells				Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM21395 (3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1 Show InChI InChI=1S/C22H22FN3O3/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	0.660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL					Assay Description Binding affinity for 5-hydroxytryptamine 2 receptor from striata of male Wistar rats by displacement of [3H]ketanserin				Bioorg Med Chem Lett 10: 509-12 (2000) BindingDB Entry DOI: 10.7270/Q24Q7T7T
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM21395 (3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1 Show InChI InChI=1S/C22H22FN3O3/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	0.660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 2 receptor from striata wistar rats by [3H]ketanserin displacement.				Bioorg Med Chem Lett 10: 2457-61 (2001) BindingDB Entry DOI: 10.7270/Q2VT1SN2
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50165019 (4-(Diethylamino)-2-butynyl alpha-phenylcyclohexane...) Show SMILES CCN(CC)CC#CCOC(=O)C(O)(C1CCCCC1)c1ccccc1 Show InChI InChI=1S/C22H31NO3/c1-3-23(4-2)17-11-12-18-26-21(24)22(25,19-13-7-5-8-14-19)20-15-9-6-10-16-20/h5,7-8,13-14,20,25H,3-4,6,9-10,15-18H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	0.780	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells				Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50165019 (4-(Diethylamino)-2-butynyl alpha-phenylcyclohexane...) Show SMILES CCN(CC)CC#CCOC(=O)C(O)(C1CCCCC1)c1ccccc1 Show InChI InChI=1S/C22H31NO3/c1-3-23(4-2)17-11-12-18-26-21(24)22(25,19-13-7-5-8-14-19)20-15-9-6-10-16-20/h5,7-8,13-14,20,25H,3-4,6,9-10,15-18H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M1 receptor expressed in Sf9 cells				Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50218395 (CHEMBL311095) Show SMILES O=C(NC1CCN(CCCCc2ccccc2)C1)C12CC3CC(CC(C3)C1)C2 |TLB:25:24:27:19.20.21,25:20:27:26.24.23,THB:23:24:19:27.22.21,23:22:19:26.24.25| Show InChI InChI=1S/C25H36N2O/c28-24(25-15-20-12-21(16-25)14-22(13-20)17-25)26-23-9-11-27(18-23)10-5-4-8-19-6-2-1-3-7-19/h1-3,6-7,20-23H,4-5,8-18H2,(H,26,28)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 1A receptor from striata of wistar rats by [3H]- 8-OH -DPAT displacement.				Bioorg Med Chem Lett 10: 2457-61 (2001) BindingDB Entry DOI: 10.7270/Q2VT1SN2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50218393 (CHEMBL79542) Show SMILES O=C(N[C@@H]1CCN(CCc2ccccc2)C1)C1CCCCC1 Show InChI InChI=1S/C19H28N2O/c22-19(17-9-5-2-6-10-17)20-18-12-14-21(15-18)13-11-16-7-3-1-4-8-16/h1,3-4,7-8,17-18H,2,5-6,9-15H2,(H,20,22)/t18-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 1A receptor from striata of wistar rats by [3H]- 8-OH -DPAT displacement.				Bioorg Med Chem Lett 10: 2457-61 (2001) BindingDB Entry DOI: 10.7270/Q2VT1SN2
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50201280 (CHEMBL394137 | {3-[(2-adamantan-1-yl-ethylamino)-m...) Show SMILES CN(C)C1(CNCCC23CC4CC(CC(C4)C2)C3)COc2ccccc2OC1 |TLB:7:8:11.10.15:13,THB:9:10:13:17.8.16,9:8:11.10.15:13,7:8:11:15.14.13,16:8:11:15.14.13,16:14:11:17.9.8| Show InChI InChI=1S/C24H36N2O2/c1-26(2)24(16-27-21-5-3-4-6-22(21)28-17-24)15-25-8-7-23-12-18-9-19(13-23)11-20(10-18)14-23/h3-6,18-20,25H,7-17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells				Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL					Assay Description Binding affinity for Dopamine receptor D2 by displacement of [3H]-spiperone				Bioorg Med Chem Lett 10: 509-12 (2000) BindingDB Entry DOI: 10.7270/Q24Q7T7T
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50201277 ((4-(2-((3-(dimethylamino)-3,4-dihydro-2H-benzo[b][...) Show SMILES CN(C)C1(CNCCC2CCC(CO)CC2)COc2ccccc2OC1 |(6.24,-16.08,;7.23,-14.91,;8.75,-15.18,;6.71,-13.46,;7.47,-12.12,;9.01,-12.11,;9.77,-10.77,;11.31,-10.76,;12.07,-9.42,;13.61,-9.42,;14.37,-8.09,;13.59,-6.75,;14.36,-5.42,;15.9,-5.41,;12.05,-6.76,;11.28,-8.1,;6.08,-12.04,;4.64,-11.66,;3.45,-12.58,;2.11,-11.81,;.78,-12.58,;.78,-14.13,;2.11,-14.9,;3.45,-14.12,;4.61,-15.01,;6.05,-14.72,)| Show InChI InChI=1S/C21H34N2O3/c1-23(2)21(15-25-19-5-3-4-6-20(19)26-16-21)14-22-12-11-17-7-9-18(13-24)10-8-17/h3-6,17-18,22,24H,7-16H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells				Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50201292 (7,8-dichloro-N,N-dimethyl-3-((2-(tetrahydro-2H-pyr...) Show SMILES CN(C)C1(CNCCC2CCOCC2)COc2cc(Cl)c(Cl)cc2OC1 Show InChI InChI=1S/C19H28Cl2N2O3/c1-23(2)19(11-22-6-3-14-4-7-24-8-5-14)12-25-17-9-15(20)16(21)10-18(17)26-13-19/h9-10,14,22H,3-8,11-13H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M1 receptor expressed in Sf9 cells				Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50201296 (4-(2-((3-(dimethylamino)-3,4-dihydro-2H-benzo[b][1...) Show SMILES CN(C)C1(CNCCC2CCC(O)CC2)COc2ccccc2OC1 |(-6.35,-15.83,;-5.36,-14.65,;-3.84,-14.92,;-5.88,-13.2,;-5.12,-11.87,;-3.58,-11.85,;-2.82,-10.51,;-1.28,-10.5,;-.52,-9.16,;1.02,-9.16,;1.78,-7.83,;1,-6.5,;1.77,-5.16,;-.54,-6.51,;-1.31,-7.85,;-6.51,-11.78,;-7.95,-11.4,;-9.14,-12.32,;-10.48,-11.56,;-11.81,-12.33,;-11.81,-13.87,;-10.48,-14.64,;-9.14,-13.86,;-7.99,-14.75,;-6.55,-14.47,)| Show InChI InChI=1S/C20H32N2O3/c1-22(2)20(13-21-12-11-16-7-9-17(23)10-8-16)14-24-18-5-3-4-6-19(18)25-15-20/h3-6,16-17,21,23H,7-15H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells				Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50201285 (3-((2-cycloheptylethylamino)methyl)-N,N-dimethyl-3...) Show SMILES CN(C)C1(CNCCC2CCCCCC2)COc2ccccc2OC1 Show InChI InChI=1S/C21H34N2O2/c1-23(2)21(15-22-14-13-18-9-5-3-4-6-10-18)16-24-19-11-7-8-12-20(19)25-17-21/h7-8,11-12,18,22H,3-6,9-10,13-17H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells				Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50201277 ((4-(2-((3-(dimethylamino)-3,4-dihydro-2H-benzo[b][...) Show SMILES CN(C)C1(CNCCC2CCC(CO)CC2)COc2ccccc2OC1 |(6.24,-16.08,;7.23,-14.91,;8.75,-15.18,;6.71,-13.46,;7.47,-12.12,;9.01,-12.11,;9.77,-10.77,;11.31,-10.76,;12.07,-9.42,;13.61,-9.42,;14.37,-8.09,;13.59,-6.75,;14.36,-5.42,;15.9,-5.41,;12.05,-6.76,;11.28,-8.1,;6.08,-12.04,;4.64,-11.66,;3.45,-12.58,;2.11,-11.81,;.78,-12.58,;.78,-14.13,;2.11,-14.9,;3.45,-14.12,;4.61,-15.01,;6.05,-14.72,)| Show InChI InChI=1S/C21H34N2O3/c1-23(2)21(15-25-19-5-3-4-6-20(19)26-16-21)14-22-12-11-17-7-9-18(13-24)10-8-17/h3-6,17-18,22,24H,7-16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells				Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50201294 (3-((2-cyclopentylethylamino)methyl)-N,N-dimethyl-3...) Show SMILES CN(C)C1(CNCCC2CCCC2)COc2ccccc2OC1 Show InChI InChI=1S/C19H30N2O2/c1-21(2)19(13-20-12-11-16-7-3-4-8-16)14-22-17-9-5-6-10-18(17)23-15-19/h5-6,9-10,16,20H,3-4,7-8,11-15H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells				Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50201283 (3-((2-cyclohexylethylamino)methyl)-N,N-dimethyl-3,...) Show SMILES CN(C)C1(CNCCC2CCCCC2)COc2ccccc2OC1 Show InChI InChI=1S/C20H32N2O2/c1-22(2)20(14-21-13-12-17-8-4-3-5-9-17)15-23-18-10-6-7-11-19(18)24-16-20/h6-7,10-11,17,21H,3-5,8-9,12-16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells				Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50201285 (3-((2-cycloheptylethylamino)methyl)-N,N-dimethyl-3...) Show SMILES CN(C)C1(CNCCC2CCCCCC2)COc2ccccc2OC1 Show InChI InChI=1S/C21H34N2O2/c1-23(2)21(15-22-14-13-18-9-5-3-4-6-10-18)16-24-19-11-7-8-12-20(19)25-17-21/h7-8,11-12,18,22H,3-6,9-10,13-17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells				Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50201296 (4-(2-((3-(dimethylamino)-3,4-dihydro-2H-benzo[b][1...) Show SMILES CN(C)C1(CNCCC2CCC(O)CC2)COc2ccccc2OC1 |(-6.35,-15.83,;-5.36,-14.65,;-3.84,-14.92,;-5.88,-13.2,;-5.12,-11.87,;-3.58,-11.85,;-2.82,-10.51,;-1.28,-10.5,;-.52,-9.16,;1.02,-9.16,;1.78,-7.83,;1,-6.5,;1.77,-5.16,;-.54,-6.51,;-1.31,-7.85,;-6.51,-11.78,;-7.95,-11.4,;-9.14,-12.32,;-10.48,-11.56,;-11.81,-12.33,;-11.81,-13.87,;-10.48,-14.64,;-9.14,-13.86,;-7.99,-14.75,;-6.55,-14.47,)| Show InChI InChI=1S/C20H32N2O3/c1-22(2)20(13-21-12-11-16-7-9-17(23)10-8-16)14-24-18-5-3-4-6-19(18)25-15-20/h3-6,16-17,21,23H,7-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells				Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50218398 (CHEMBL1907861) Show SMILES [H][C@@]1(CCN(CCc2ccc(F)cc2)C1)NC(=O)C12CC3([H])CC([H])(CC([H])(C3)C1)C2 |r,TLB:28:20:30:29.26.25,28:26:30:19.20.22,22:23:29:19.20.28,THB:22:20:29:30.23.25| Show InChI InChI=1S/C23H31FN2O/c24-20-3-1-16(2-4-20)5-7-26-8-6-21(15-26)25-22(27)23-12-17-9-18(13-23)11-19(10-17)14-23/h1-4,17-19,21H,5-15H2,(H,25,27)/t17?,18?,19?,21-,23?/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description Ability to displace [3H]-Prazosin binding to Alpha-1 adrenergic receptor				Bioorg Med Chem Lett 10: 2457-61 (2001) BindingDB Entry DOI: 10.7270/Q2VT1SN2
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50201294 (3-((2-cyclopentylethylamino)methyl)-N,N-dimethyl-3...) Show SMILES CN(C)C1(CNCCC2CCCC2)COc2ccccc2OC1 Show InChI InChI=1S/C19H30N2O2/c1-21(2)19(13-20-12-11-16-7-3-4-8-16)14-22-17-9-5-6-10-18(17)23-15-19/h5-6,9-10,16,20H,3-4,7-8,11-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells				Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM21395 (3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1 Show InChI InChI=1S/C22H22FN3O3/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description Ability to displace [3H]-Prazosin binding to Alpha-1 adrenergic receptor				Bioorg Med Chem Lett 10: 2457-61 (2001) BindingDB Entry DOI: 10.7270/Q2VT1SN2
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50190677 ((R)-3'-(3-bromobenzo[b]thiophen-5-yl)spiro[1-azabi...) Show SMILES Brc1coc2ccc(cc12)N1C[C@]2(CN3CCC2CC3)OC1=O |wU:12.23,TLB:11:12:16.15:18.19,THB:20:12:16.15:18.19,(18.37,-17.66,;16.95,-18.23,;16.58,-19.73,;15.04,-19.83,;14.48,-18.4,;13.03,-17.88,;12.76,-16.36,;13.94,-15.36,;15.38,-15.89,;15.65,-17.41,;13.87,-13.82,;12.58,-12.98,;12.99,-11.49,;12.71,-10.09,;11.36,-9.48,;9.89,-10.13,;10.08,-11.51,;11.62,-10.85,;11.87,-8.95,;11.43,-7.84,;14.52,-11.41,;15.07,-12.85,;16.56,-13.26,)| Show InChI InChI=1S/C17H17BrN2O3/c18-14-8-22-15-2-1-12(7-13(14)15)20-10-17(23-16(20)21)9-19-5-3-11(17)4-6-19/h1-2,7-8,11H,3-6,9-10H2/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Displacement of [125I]alpha-BTX from alpha-7 nAChR in rat hippocampus membrane				J Med Chem 49: 4374-83 (2006) Article DOI: 10.1021/jm060249c BindingDB Entry DOI: 10.7270/Q2BR8T08
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50190686 ((R)-3'-(2,3-dimethylbenzo[b]thiophen-5-yl)spiro[1-...) Show SMILES Cc1oc2ccc(cc2c1C)N1C[C@]2(CN3CCC2CC3)OC1=O |wU:13.24,TLB:12:13:17.16:19.20,THB:21:13:17.16:19.20,(27.52,-20.9,;26.53,-19.72,;25,-19.82,;24.43,-18.39,;22.98,-17.87,;22.71,-16.35,;23.89,-15.35,;25.34,-15.88,;25.6,-17.4,;26.9,-18.22,;28.33,-17.65,;23.82,-13.81,;22.53,-12.96,;22.94,-11.47,;22.66,-10.07,;21.3,-9.46,;19.83,-10.11,;20.03,-11.49,;21.57,-10.83,;21.82,-8.93,;21.38,-7.82,;24.48,-11.4,;25.02,-12.84,;26.52,-13.24,)| Show InChI InChI=1S/C19H22N2O3/c1-12-13(2)23-17-4-3-15(9-16(12)17)21-11-19(24-18(21)22)10-20-7-5-14(19)6-8-20/h3-4,9,14H,5-8,10-11H2,1-2H3/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Displacement of [125I]alpha-BTX from alpha-7 nAChR in rat hippocampus membrane				J Med Chem 49: 4374-83 (2006) Article DOI: 10.1021/jm060249c BindingDB Entry DOI: 10.7270/Q2BR8T08
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50190696 ((2S)-3'-(5-bromothien-2-yl)-2'H-spiro[4-azabicyclo...) Show SMILES Brc1ccc(s1)N1C[C@]2(CN3CCC2CC3)OC1=O |wU:8.18,TLB:7:8:12.11:14.15,THB:16:8:12.11:14.15,(5.67,-5.62,;4.7,-4.42,;3.16,-4.5,;2.61,-3.06,;3.81,-2.09,;5.1,-2.93,;3.74,-.55,;2.45,.29,;2.85,1.77,;2.57,3.17,;1.22,3.79,;-.25,3.14,;-.05,1.76,;1.49,2.42,;1.74,4.32,;1.29,5.43,;4.39,1.85,;4.93,.41,;6.42,.01,)| Show InChI InChI=1S/C13H15BrN2O2S/c14-10-1-2-11(19-10)16-8-13(18-12(16)17)7-15-5-3-9(13)4-6-15/h1-2,9H,3-8H2/t13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Displacement of [125I]alpha-BTX from alpha-7 nAChR in rat hippocampus membrane				J Med Chem 49: 4374-83 (2006) Article DOI: 10.1021/jm060249c BindingDB Entry DOI: 10.7270/Q2BR8T08
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50164606 ((2R)-3'-(5-bromothien-2-yl)-2'H-spiro[4-azabicyclo...) Show SMILES Brc1ccc(s1)N1C[C@@]2(CN3CCC2CC3)OC1=O |wU:8.18,(9.64,1.56,;8.17,1.11,;7.65,-.34,;6.1,-.29,;5.67,1.18,;6.94,2.06,;4.22,1.7,;2.95,.82,;1.71,1.77,;1.71,.23,;.38,-.55,;-.94,.23,;-.94,1.77,;.38,2.54,;-.23,1.35,;.87,.72,;2.25,3.22,;3.79,3.17,;4.73,4.39,)| Show InChI InChI=1S/C13H15BrN2O2S/c14-10-1-2-11(19-10)16-8-13(18-12(16)17)7-15-5-3-9(13)4-6-15/h1-2,9H,3-8H2/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Inhibition of [125I]alpha-bungarotoxin binding to rat nicotinic acetylcholine receptor alpha7				J Med Chem 48: 2678-86 (2005) Article DOI: 10.1021/jm049188d BindingDB Entry DOI: 10.7270/Q2M0466W
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50201299 (7-fluoro-N,N-dimethyl-3-((2-(tetrahydro-2H-pyran-4...) Show SMILES CN(C)C1(CNCCC2CCOCC2)COc2ccc(F)cc2OC1 |w:3.3| Show InChI InChI=1S/C19H29FN2O3/c1-22(2)19(12-21-8-5-15-6-9-23-10-7-15)13-24-17-4-3-16(20)11-18(17)25-14-19/h3-4,11,15,21H,5-10,12-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells				Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50086861 (3-Methylsulfanyl-N-((S)-1-phenethyl-pyrrolidin-2-y...) Show SMILES CSc1cccc(c1)C(=O)NC[C@@H]1CCCN1CCc1ccccc1 Show InChI InChI=1S/C21H26N2OS/c1-25-20-11-5-9-18(15-20)21(24)22-16-19-10-6-13-23(19)14-12-17-7-3-2-4-8-17/h2-5,7-9,11,15,19H,6,10,12-14,16H2,1H3,(H,22,24)/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from rat striata 5-hydroxytryptamine 1A receptor				Bioorg Med Chem Lett 10: 509-12 (2000) BindingDB Entry DOI: 10.7270/Q24Q7T7T
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50086856 (CHEMBL147279 | N-((S)-1-Phenethyl-pyrrolidin-2-ylm...) Show SMILES O=C(NC[C@@H]1CCCN1CCc1ccccc1)c1ccccc1 Show InChI InChI=1S/C20H24N2O/c23-20(18-10-5-2-6-11-18)21-16-19-12-7-14-22(19)15-13-17-8-3-1-4-9-17/h1-6,8-11,19H,7,12-16H2,(H,21,23)/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from rat striata 5-hydroxytryptamine 1A receptor				Bioorg Med Chem Lett 10: 509-12 (2000) BindingDB Entry DOI: 10.7270/Q24Q7T7T
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50201284 (3-((cyclohexylmethylamino)methyl)-N,N-dimethyl-3,4...) Show SMILES CN(C)C1(CNCC2CCCCC2)COc2ccccc2OC1 Show InChI InChI=1S/C19H30N2O2/c1-21(2)19(13-20-12-16-8-4-3-5-9-16)14-22-17-10-6-7-11-18(17)23-15-19/h6-7,10-11,16,20H,3-5,8-9,12-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells				Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50201299 (7-fluoro-N,N-dimethyl-3-((2-(tetrahydro-2H-pyran-4...) Show SMILES CN(C)C1(CNCCC2CCOCC2)COc2ccc(F)cc2OC1 |w:3.3| Show InChI InChI=1S/C19H29FN2O3/c1-22(2)19(12-21-8-5-15-6-9-23-10-7-15)13-24-17-4-3-16(20)11-18(17)25-14-19/h3-4,11,15,21H,5-10,12-14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells				Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50093797 (Adamantane-1-carboxylic acid {1-[2-(4-cyano-phenyl...) Show SMILES O=C(NC1CCN(CCc2ccc(cc2)C#N)C1)C12CC3CC(CC(C3)C1)C2 |TLB:21:22:26:19.20.25,THB:23:24:19:27.22.21,23:22:19:26.24.25,21:20:26:27.22.23| Show InChI InChI=1S/C24H31N3O/c25-15-18-3-1-17(2-4-18)5-7-27-8-6-22(16-27)26-23(28)24-12-19-9-20(13-24)11-21(10-19)14-24/h1-4,19-22H,5-14,16H2,(H,26,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 2 receptor from striata wistar rats by [3H]ketanserin displacement.				Bioorg Med Chem Lett 10: 2457-61 (2001) BindingDB Entry DOI: 10.7270/Q2VT1SN2
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50201276 (3-((2-(3,6-dihydro-2H-thiopyran-4-yl)ethylamino)me...) Show SMILES CN(C)C1(CNCCC2=CCSCC2)COc2ccccc2OC1 |t:8| Show InChI InChI=1S/C19H28N2O2S/c1-21(2)19(13-20-10-7-16-8-11-24-12-9-16)14-22-17-5-3-4-6-18(17)23-15-19/h3-6,8,20H,7,9-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells				Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50201280 (CHEMBL394137 | {3-[(2-adamantan-1-yl-ethylamino)-m...) Show SMILES CN(C)C1(CNCCC23CC4CC(CC(C4)C2)C3)COc2ccccc2OC1 |TLB:7:8:11.10.15:13,THB:9:10:13:17.8.16,9:8:11.10.15:13,7:8:11:15.14.13,16:8:11:15.14.13,16:14:11:17.9.8| Show InChI InChI=1S/C24H36N2O2/c1-26(2)24(16-27-21-5-3-4-6-22(21)28-17-24)15-25-8-7-23-12-18-9-19(13-23)11-20(10-18)14-23/h3-6,18-20,25H,7-17H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M1 receptor expressed in Sf9 cells				Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50201287 (CHEMBL435353 | N,N-dimethyl-3-((2-(tetrahydro-2H-p...) Show SMILES CN(C)C1(CNCCC2CCOCC2)COc2ccccc2OC1 Show InChI InChI=1S/C19H30N2O3/c1-21(2)19(13-20-10-7-16-8-11-22-12-9-16)14-23-17-5-3-4-6-18(17)24-15-19/h3-6,16,20H,7-15H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells				Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50201283 (3-((2-cyclohexylethylamino)methyl)-N,N-dimethyl-3,...) Show SMILES CN(C)C1(CNCCC2CCCCC2)COc2ccccc2OC1 Show InChI InChI=1S/C20H32N2O2/c1-22(2)20(14-21-13-12-17-8-4-3-5-9-17)15-23-18-10-6-7-11-19(18)24-16-20/h6-7,10-11,17,21H,3-5,8-9,12-16H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells				Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50218396 (CHEMBL315259) Show SMILES O=C(N[C@H]1CCN(CCc2ccccc2)C1)C12CC3CC(CC(C3)C1)C2 |TLB:23:22:25:17.18.19,23:18:25:24.22.21,THB:21:22:17:25.20.19,21:20:17:24.22.23| Show InChI InChI=1S/C23H32N2O/c26-22(23-13-18-10-19(14-23)12-20(11-18)15-23)24-21-7-9-25(16-21)8-6-17-4-2-1-3-5-17/h1-5,18-21H,6-16H2,(H,24,26)/t18?,19?,20?,21-,23?/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	6.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description Ability to displace [3H]-Prazosin binding to Alpha-1 adrenergic receptor				Bioorg Med Chem Lett 10: 2457-61 (2001) BindingDB Entry DOI: 10.7270/Q2VT1SN2
					More data for this Ligand-Target Pair

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