Compile Data Set for Download or QSAR

Found 20 hits with Last Name = 'garner' and Initial = 'j'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054245 (5-Chloro-N-cyclopropylmethyl-2-methyl-N-propyl-N''...) Show SMILES CCCN(CC1CC1)c1nc(C)nc(Nc2c(Cl)cc(Cl)cc2Cl)c1Cl Show InChI InChI=1S/C18H20Cl4N4/c1-3-6-26(9-11-4-5-11)18-15(22)17(23-10(2)24-18)25-16-13(20)7-12(19)8-14(16)21/h7-8,11H,3-6,9H2,1-2H3,(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Wollongong Curated by ChEMBL					Assay Description Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.				J Med Chem 42: 2351-7 (1999) Article DOI: 10.1021/jm9900117 BindingDB Entry DOI: 10.7270/Q2WS8SF0
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054252 (5-Bromo-N-cyclopropylmethyl-2-methyl-N-propyl-N'-(...) Show SMILES CCCN(CC1CC1)c1nc(C)nc(Nc2c(Cl)cc(Cl)cc2Cl)c1Br Show InChI InChI=1S/C18H20BrCl3N4/c1-3-6-26(9-11-4-5-11)18-15(19)17(23-10(2)24-18)25-16-13(21)7-12(20)8-14(16)22/h7-8,11H,3-6,9H2,1-2H3,(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Wollongong Curated by ChEMBL					Assay Description Ability to inhibit [125I]-CRH binding to human Corticotropin releasing factor receptor 1				J Med Chem 42: 2351-7 (1999) Article DOI: 10.1021/jm9900117 BindingDB Entry DOI: 10.7270/Q2WS8SF0
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054250 (CHEMBL306482 | N-Cyclopropylmethyl-2,5-dimethyl-N-...) Show SMILES CCCN(CC1CC1)c1nc(C)nc(Nc2c(Cl)cc(Cl)cc2Cl)c1C Show InChI InChI=1S/C19H23Cl3N4/c1-4-7-26(10-13-5-6-13)19-11(2)18(23-12(3)24-19)25-17-15(21)8-14(20)9-16(17)22/h8-9,13H,4-7,10H2,1-3H3,(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Wollongong Curated by ChEMBL					Assay Description Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.				J Med Chem 42: 2351-7 (1999) Article DOI: 10.1021/jm9900117 BindingDB Entry DOI: 10.7270/Q2WS8SF0
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054248 (2,5-Dimethyl-N,N-dipropyl-N'-(2,4,6-trichloro-phen...) Show SMILES CCCN(CCC)c1nc(C)nc(Nc2c(Cl)cc(Cl)cc2Cl)c1C Show InChI InChI=1S/C18H23Cl3N4/c1-5-7-25(8-6-2)18-11(3)17(22-12(4)23-18)24-16-14(20)9-13(19)10-15(16)21/h9-10H,5-8H2,1-4H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Wollongong Curated by ChEMBL					Assay Description Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.				J Med Chem 42: 2351-7 (1999) Article DOI: 10.1021/jm9900117 BindingDB Entry DOI: 10.7270/Q2WS8SF0
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054253 (CHEMBL77716 | N-Cyclopropylmethyl-5-ethyl-2-methyl...) Show SMILES CCCN(CC1CC1)c1nc(C)nc(Nc2c(Cl)cc(Cl)cc2Cl)c1CC Show InChI InChI=1S/C20H25Cl3N4/c1-4-8-27(11-13-6-7-13)20-15(5-2)19(24-12(3)25-20)26-18-16(22)9-14(21)10-17(18)23/h9-10,13H,4-8,11H2,1-3H3,(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Wollongong Curated by ChEMBL					Assay Description Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.				J Med Chem 42: 2351-7 (1999) Article DOI: 10.1021/jm9900117 BindingDB Entry DOI: 10.7270/Q2WS8SF0
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054225 (CHEMBL306618 | N-Cyclopropylmethyl-6-methyl-N-prop...) Show SMILES CCCN(CC1CC1)c1nc(C)nc(Nc2c(C)cc(C)cc2C)n1 Show InChI InChI=1S/C20H29N5/c1-6-9-25(12-17-7-8-17)20-22-16(5)21-19(24-20)23-18-14(3)10-13(2)11-15(18)4/h10-11,17H,6-9,12H2,1-5H3,(H,21,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Wollongong Curated by ChEMBL					Assay Description Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.				J Med Chem 42: 2351-7 (1999) Article DOI: 10.1021/jm9900117 BindingDB Entry DOI: 10.7270/Q2WS8SF0
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054226 (CHEMBL77391 | N,N-Diallyl-6-methyl-N'-(2,4,6-trime...) Show SMILES Cc1cc(C)c(Nc2nc(C)nc(n2)N(CC=C)CC=C)c(C)c1 Show InChI InChI=1S/C19H25N5/c1-7-9-24(10-8-2)19-21-16(6)20-18(23-19)22-17-14(4)11-13(3)12-15(17)5/h7-8,11-12H,1-2,9-10H2,3-6H3,(H,20,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	115	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Wollongong Curated by ChEMBL					Assay Description Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.				J Med Chem 42: 2351-7 (1999) Article DOI: 10.1021/jm9900117 BindingDB Entry DOI: 10.7270/Q2WS8SF0
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054230 (6-Methyl-N,N-dipropyl-N'-(2,4,6-trimethyl-phenyl)-...) Show SMILES CCCN(CCC)c1nc(C)nc(Nc2c(C)cc(C)cc2C)n1 Show InChI InChI=1S/C19H29N5/c1-7-9-24(10-8-2)19-21-16(6)20-18(23-19)22-17-14(4)11-13(3)12-15(17)5/h11-12H,7-10H2,1-6H3,(H,20,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Wollongong Curated by ChEMBL					Assay Description Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.				J Med Chem 42: 2351-7 (1999) Article DOI: 10.1021/jm9900117 BindingDB Entry DOI: 10.7270/Q2WS8SF0
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054246 (CHEMBL77006 | N-Cyclopropylmethyl-2-methyl-N-propy...) Show SMILES CCCN(CC1CC1)c1cc(Nc2c(Cl)cc(Cl)cc2Cl)nc(C)n1 Show InChI InChI=1S/C18H21Cl3N4/c1-3-6-25(10-12-4-5-12)17-9-16(22-11(2)23-17)24-18-14(20)7-13(19)8-15(18)21/h7-9,12H,3-6,10H2,1-2H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	253	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Wollongong Curated by ChEMBL					Assay Description Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.				J Med Chem 42: 2351-7 (1999) Article DOI: 10.1021/jm9900117 BindingDB Entry DOI: 10.7270/Q2WS8SF0
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054246 (CHEMBL77006 | N-Cyclopropylmethyl-2-methyl-N-propy...) Show SMILES CCCN(CC1CC1)c1cc(Nc2c(Cl)cc(Cl)cc2Cl)nc(C)n1 Show InChI InChI=1S/C18H21Cl3N4/c1-3-6-25(10-12-4-5-12)17-9-16(22-11(2)23-17)24-18-14(20)7-13(19)8-15(18)21/h7-9,12H,3-6,10H2,1-2H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	253	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Wollongong Curated by ChEMBL					Assay Description Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.				J Med Chem 42: 2351-7 (1999) Article DOI: 10.1021/jm9900117 BindingDB Entry DOI: 10.7270/Q2WS8SF0
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054216 (CHEMBL307419 | N-Benzyl-6-methyl-N-propyl-N'-(2,4,...) Show SMILES CCCN(Cc1ccccc1)c1nc(C)nc(Nc2c(C)cc(C)cc2C)n1 Show InChI InChI=1S/C23H29N5/c1-6-12-28(15-20-10-8-7-9-11-20)23-25-19(5)24-22(27-23)26-21-17(3)13-16(2)14-18(21)4/h7-11,13-14H,6,12,15H2,1-5H3,(H,24,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Wollongong Curated by ChEMBL					Assay Description Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.				J Med Chem 42: 2351-7 (1999) Article DOI: 10.1021/jm9900117 BindingDB Entry DOI: 10.7270/Q2WS8SF0
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054221 (CHEMBL419636 | N,N-Dibutyl-6-methyl-N'-(2,4,6-trim...) Show SMILES CCCCN(CCCC)c1nc(C)nc(Nc2c(C)cc(C)cc2C)n1 Show InChI InChI=1S/C21H33N5/c1-7-9-11-26(12-10-8-2)21-23-18(6)22-20(25-21)24-19-16(4)13-15(3)14-17(19)5/h13-14H,7-12H2,1-6H3,(H,22,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Wollongong Curated by ChEMBL					Assay Description Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.				J Med Chem 42: 2351-7 (1999) Article DOI: 10.1021/jm9900117 BindingDB Entry DOI: 10.7270/Q2WS8SF0
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054239 (CHEMBL78035 | [4-(3,6-Dihydro-2H-pyridin-1-yl)-6-m...) Show SMILES Cc1cc(C)c(Nc2nc(C)nc(n2)N2CCC=CC2)c(C)c1 |c:18| Show InChI InChI=1S/C18H23N5/c1-12-10-13(2)16(14(3)11-12)21-17-19-15(4)20-18(22-17)23-8-6-5-7-9-23/h5-6,10-11H,7-9H2,1-4H3,(H,19,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Wollongong Curated by ChEMBL					Assay Description Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.				J Med Chem 42: 2351-7 (1999) Article DOI: 10.1021/jm9900117 BindingDB Entry DOI: 10.7270/Q2WS8SF0
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054219 (CHEMBL305671 | N-Benzyl-N-butyl-6-methyl-N'-(2,4,6...) Show SMILES CCCCN(Cc1ccccc1)c1nc(C)nc(Nc2c(C)cc(C)cc2C)n1 Show InChI InChI=1S/C24H31N5/c1-6-7-13-29(16-21-11-9-8-10-12-21)24-26-20(5)25-23(28-24)27-22-18(3)14-17(2)15-19(22)4/h8-12,14-15H,6-7,13,16H2,1-5H3,(H,25,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Wollongong Curated by ChEMBL					Assay Description Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.				J Med Chem 42: 2351-7 (1999) Article DOI: 10.1021/jm9900117 BindingDB Entry DOI: 10.7270/Q2WS8SF0
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054255 (CHEMBL80806 | N-Cyclopropylmethyl-2-methyl-N-propy...) Show SMILES CCCN(CC1CC1)c1cc(Nc2c(C)cc(C)cc2C)nc(C)n1 Show InChI InChI=1S/C21H30N4/c1-6-9-25(13-18-7-8-18)20-12-19(22-17(5)23-20)24-21-15(3)10-14(2)11-16(21)4/h10-12,18H,6-9,13H2,1-5H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.39E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Wollongong Curated by ChEMBL					Assay Description Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.				J Med Chem 42: 2351-7 (1999) Article DOI: 10.1021/jm9900117 BindingDB Entry DOI: 10.7270/Q2WS8SF0
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054223 (CHEMBL307871 | N-Benzyl-N-ethyl-6-methyl-N'-(2,4,6...) Show SMILES CCN(Cc1ccccc1)c1nc(C)nc(Nc2c(C)cc(C)cc2C)n1 Show InChI InChI=1S/C22H27N5/c1-6-27(14-19-10-8-7-9-11-19)22-24-18(5)23-21(26-22)25-20-16(3)12-15(2)13-17(20)4/h7-13H,6,14H2,1-5H3,(H,23,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.47E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Wollongong Curated by ChEMBL					Assay Description Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.				J Med Chem 42: 2351-7 (1999) Article DOI: 10.1021/jm9900117 BindingDB Entry DOI: 10.7270/Q2WS8SF0
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054241 (6-Methyl-N-(4-trifluoromethyl-benzyl)-N'-(2,4,6-tr...) Show SMILES Cc1cc(C)c(Nc2nc(C)nc(NCc3ccc(cc3)C(F)(F)F)n2)c(C)c1 Show InChI InChI=1S/C21H22F3N5/c1-12-9-13(2)18(14(3)10-12)28-20-27-15(4)26-19(29-20)25-11-16-5-7-17(8-6-16)21(22,23)24/h5-10H,11H2,1-4H3,(H2,25,26,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.69E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Wollongong Curated by ChEMBL					Assay Description Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.				J Med Chem 42: 2351-7 (1999) Article DOI: 10.1021/jm9900117 BindingDB Entry DOI: 10.7270/Q2WS8SF0
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054234 (6,N-Dimethyl-N-phenethyl-N'-(2,4,6-trimethyl-pheny...) Show SMILES CN(CCc1ccccc1)c1nc(C)nc(Nc2c(C)cc(C)cc2C)n1 Show InChI InChI=1S/C22H27N5/c1-15-13-16(2)20(17(3)14-15)25-21-23-18(4)24-22(26-21)27(5)12-11-19-9-7-6-8-10-19/h6-10,13-14H,11-12H2,1-5H3,(H,23,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Wollongong Curated by ChEMBL					Assay Description Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.				J Med Chem 42: 2351-7 (1999) Article DOI: 10.1021/jm9900117 BindingDB Entry DOI: 10.7270/Q2WS8SF0
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50078345 (CHEMBL309789 | N-Cyclopropylmethyl-6-methyl-N-prop...) Show SMILES CCCN(CC1CC1)c1nc(C)nc(Nc2c(OC)cc(OC)cc2OC)n1 Show InChI InChI=1S/C20H29N5O3/c1-6-9-25(12-14-7-8-14)20-22-13(2)21-19(24-20)23-18-16(27-4)10-15(26-3)11-17(18)28-5/h10-11,14H,6-9,12H2,1-5H3,(H,21,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Wollongong Curated by ChEMBL					Assay Description Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.				J Med Chem 42: 2351-7 (1999) Article DOI: 10.1021/jm9900117 BindingDB Entry DOI: 10.7270/Q2WS8SF0
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054235 (CHEMBL78203 | N-Cyclopropylmethyl-6-ethyl-N-propyl...) Show SMILES CCCN(CC1CC1)c1nc(CC)nc(Nc2c(C)cc(C)cc2C)n1 Show InChI InChI=1S/C21H31N5/c1-6-10-26(13-17-8-9-17)21-23-18(7-2)22-20(25-21)24-19-15(4)11-14(3)12-16(19)5/h11-12,17H,6-10,13H2,1-5H3,(H,22,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Wollongong Curated by ChEMBL					Assay Description Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.				J Med Chem 42: 2351-7 (1999) Article DOI: 10.1021/jm9900117 BindingDB Entry DOI: 10.7270/Q2WS8SF0
					More data for this Ligand-Target Pair