Compile Data Set for Download or QSAR

Found 447 hits with Last Name = 'goettert' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50494296 (CHEMBL3086685) Show SMILES Fc1ccc(Nc2ccc3c(OCc4ccc(OCCN5CCOCC5)cc4C3=O)c2)cc1NC(=O)c1ccccc1 Show InChI InChI=1S/C33H30FN3O5/c34-29-11-8-24(18-30(29)36-33(39)22-4-2-1-3-5-22)35-25-7-10-27-31(19-25)42-21-23-6-9-26(20-28(23)32(27)38)41-17-14-37-12-15-40-16-13-37/h1-11,18-20,35H,12-17,21H2,(H,36,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Competitive inhibition of p38alpha MAP kinase (unknown origin) in presence of 100 uM ATP				J Med Chem 56: 8561-78 (2013) Article DOI: 10.1021/jm401276h BindingDB Entry DOI: 10.7270/Q2Q81H2C
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50494284 (CHEMBL3087471) Show SMILES Cc1cc(F)c(NC(=O)c2ccsc2)cc1Nc1ccc2c(OCc3ccc(OC[C@H](O)CO)cc3C2=O)c1 |r| Show InChI InChI=1S/C29H25FN2O6S/c1-16-8-24(30)26(32-29(36)18-6-7-39-15-18)11-25(16)31-19-3-5-22-27(9-19)38-13-17-2-4-21(10-23(17)28(22)35)37-14-20(34)12-33/h2-11,15,20,31,33-34H,12-14H2,1H3,(H,32,36)/t20-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Competitive inhibition of p38alpha MAP kinase (unknown origin) in presence of 100 uM ATP				J Med Chem 56: 8561-78 (2013) Article DOI: 10.1021/jm401276h BindingDB Entry DOI: 10.7270/Q2Q81H2C
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50494256 (CHEMBL3087469) Show SMILES Cc1cc(F)c(NC(=O)c2ccsc2)cc1Nc1ccc2c(OCc3ccc(OCCN4CCOCC4)cc3C2=O)c1 Show InChI InChI=1S/C32H30FN3O5S/c1-20-14-27(33)29(35-32(38)22-6-13-42-19-22)17-28(20)34-23-3-5-25-30(15-23)41-18-21-2-4-24(16-26(21)31(25)37)40-12-9-36-7-10-39-11-8-36/h2-6,13-17,19,34H,7-12,18H2,1H3,(H,35,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Competitive inhibition of p38alpha MAP kinase (unknown origin) in presence of 100 uM ATP				J Med Chem 56: 8561-78 (2013) Article DOI: 10.1021/jm401276h BindingDB Entry DOI: 10.7270/Q2Q81H2C
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50494261 (CHEMBL3087470) Show SMILES Cc1cc(F)c(NC(=O)c2ccsc2)cc1Nc1ccc2c(OCc3ccc(OC[C@H]4COC(C)(C)O4)cc3C2=O)c1 |r| Show InChI InChI=1S/C32H29FN2O6S/c1-18-10-26(33)28(35-31(37)20-8-9-42-17-20)13-27(18)34-21-5-7-24-29(11-21)39-14-19-4-6-22(12-25(19)30(24)36)38-15-23-16-40-32(2,3)41-23/h4-13,17,23,34H,14-16H2,1-3H3,(H,35,37)/t23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Competitive inhibition of p38alpha MAP kinase (unknown origin) in presence of 100 uM ATP				J Med Chem 56: 8561-78 (2013) Article DOI: 10.1021/jm401276h BindingDB Entry DOI: 10.7270/Q2Q81H2C
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50343492 ((S)-4-(4-(4-fluorophenyl)-2-(methylsulfinyl)-1H-im...) Show SMILES CC(C)Nc1cc(ccn1)-c1nc([nH]c1-c1ccc(F)cc1)[S@](C)=O |r| Show InChI InChI=1S/C18H19FN4OS/c1-11(2)21-15-10-13(8-9-20-15)17-16(22-18(23-17)25(3)24)12-4-6-14(19)7-5-12/h4-11H,1-3H3,(H,20,21)(H,22,23)/t25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Tu£bingen Curated by ChEMBL					Assay Description Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assay				J Med Chem 54: 3283-97 (2011) Article DOI: 10.1021/jm101623p BindingDB Entry DOI: 10.7270/Q2W959H4
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50343508 (4-(4-(4-Fluorophenyl)-2-(methylthio)-1H-imidazol-5...) Show SMILES CSc1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc(NC(C)C)c1 Show InChI InChI=1S/C18H19FN4S/c1-11(2)21-15-10-13(8-9-20-15)17-16(22-18(23-17)24-3)12-4-6-14(19)7-5-12/h4-11H,1-3H3,(H,20,21)(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Tu£bingen Curated by ChEMBL					Assay Description Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assay				J Med Chem 54: 3283-97 (2011) Article DOI: 10.1021/jm101623p BindingDB Entry DOI: 10.7270/Q2W959H4
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50343505 ((S)-4-(4-(4-fluorophenyl)-2-(isopropylsulfinyl)-1H...) Show SMILES CC(C)Nc1cc(ccn1)-c1nc([nH]c1-c1ccc(F)cc1)[S@@](=O)C(C)C |r| Show InChI InChI=1S/C20H23FN4OS/c1-12(2)23-17-11-15(9-10-22-17)19-18(14-5-7-16(21)8-6-14)24-20(25-19)27(26)13(3)4/h5-13H,1-4H3,(H,22,23)(H,24,25)/t27-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Tu£bingen Curated by ChEMBL					Assay Description Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assay				J Med Chem 54: 3283-97 (2011) Article DOI: 10.1021/jm101623p BindingDB Entry DOI: 10.7270/Q2W959H4
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398456 (CHEMBL2179119) Show SMILES Oc1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc2[nH]c(cc12)-c1ccccc1 Show InChI InChI=1S/C28H19FN4O/c29-20-10-6-18(7-11-20)25-26(33-27(32-25)19-8-12-21(34)13-9-19)22-14-15-30-28-23(22)16-24(31-28)17-4-2-1-3-5-17/h1-16,34H,(H,30,31)(H,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tuebingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK				J Med Chem 55: 8429-39 (2012) Article DOI: 10.1021/jm300852w BindingDB Entry DOI: 10.7270/Q2765GGT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398191 (CHEMBL2182085) Show SMILES Cc1cc(F)c(NC(=O)c2ccsc2)cc1Nc1ccc2c(CCCCC2=O)c1 Show InChI InChI=1S/C23H21FN2O2S/c1-14-10-19(24)21(26-23(28)16-8-9-29-13-16)12-20(14)25-17-6-7-18-15(11-17)4-2-3-5-22(18)27/h6-13,25H,2-5H2,1H3,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50494262 (CHEMBL3086686) Show SMILES Fc1ccc(NC(=O)c2ccccc2)cc1Nc1ccc2c(OCc3ccc(OCCN4CCOCC4)cc3C2=O)c1 Show InChI InChI=1S/C33H30FN3O5/c34-29-11-8-24(36-33(39)22-4-2-1-3-5-22)18-30(29)35-25-7-10-27-31(19-25)42-21-23-6-9-26(20-28(23)32(27)38)41-17-14-37-12-15-40-16-13-37/h1-11,18-20,35H,12-17,21H2,(H,36,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Competitive inhibition of p38alpha MAP kinase (unknown origin) in presence of 100 uM ATP				J Med Chem 56: 8561-78 (2013) Article DOI: 10.1021/jm401276h BindingDB Entry DOI: 10.7270/Q2Q81H2C
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50503009 (CHEMBL4526183) Show SMILES NC(=O)c1nc(C2CCCCC2)c([nH]1)-c1ccnc(NC(=O)C2CC2)c1 Show InChI InChI=1S/C19H23N5O2/c20-17(25)18-23-15(11-4-2-1-3-5-11)16(24-18)13-8-9-21-14(10-13)22-19(26)12-6-7-12/h8-12H,1-7H2,(H2,20,25)(H,23,24)(H,21,22,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard Karls Universit£t T£bingen Curated by ChEMBL					Assay Description Inhibition of GSK3beta (unknown origin) by ADP-Glo assay				ACS Med Chem Lett 10: 1407-1414 (2019) Article DOI: 10.1021/acsmedchemlett.9b00177 BindingDB Entry DOI: 10.7270/Q2SQ93N5
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50503017 (CHEMBL4483032) Show SMILES NC(=O)c1nc(C2CC2)c([nH]1)-c1ccnc(NC(=O)C2CC2)c1 Show InChI InChI=1S/C16H17N5O2/c17-14(22)15-20-12(8-1-2-8)13(21-15)10-5-6-18-11(7-10)19-16(23)9-3-4-9/h5-9H,1-4H2,(H2,17,22)(H,20,21)(H,18,19,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard Karls Universit£t T£bingen Curated by ChEMBL					Assay Description Inhibition of GSK3beta (unknown origin) by ADP-Glo assay				ACS Med Chem Lett 10: 1407-1414 (2019) Article DOI: 10.1021/acsmedchemlett.9b00177 BindingDB Entry DOI: 10.7270/Q2SQ93N5
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50343506 ((R)-4-(4-(4-fluorophenyl)-2-(isopropylsulfinyl)-1H...) Show SMILES CC(C)Nc1cc(ccn1)-c1nc([nH]c1-c1ccc(F)cc1)[S@](=O)C(C)C |r| Show InChI InChI=1S/C20H23FN4OS/c1-12(2)23-17-11-15(9-10-22-17)19-18(14-5-7-16(21)8-6-14)24-20(25-19)27(26)13(3)4/h5-13H,1-4H3,(H,22,23)(H,24,25)/t27-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Tu£bingen Curated by ChEMBL					Assay Description Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assay				J Med Chem 54: 3283-97 (2011) Article DOI: 10.1021/jm101623p BindingDB Entry DOI: 10.7270/Q2W959H4
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50343507 (4-(4-(4-Fluorophenyl)-2-(isopropylthio)-1H-imidazo...) Show SMILES CC(C)Nc1cc(ccn1)-c1nc(SC(C)C)[nH]c1-c1ccc(F)cc1 Show InChI InChI=1S/C20H23FN4S/c1-12(2)23-17-11-15(9-10-22-17)19-18(14-5-7-16(21)8-6-14)24-20(25-19)26-13(3)4/h5-13H,1-4H3,(H,22,23)(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Tu£bingen Curated by ChEMBL					Assay Description Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assay				J Med Chem 54: 3283-97 (2011) Article DOI: 10.1021/jm101623p BindingDB Entry DOI: 10.7270/Q2W959H4
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398165 (CHEMBL2182072) Show SMILES Fc1ccc(Nc2ccc3c(CCc4ccccc4C3=O)c2)cc1NC(=O)c1ccoc1 Show InChI InChI=1S/C26H19FN2O3/c27-23-10-8-20(14-24(23)29-26(31)18-11-12-32-15-18)28-19-7-9-22-17(13-19)6-5-16-3-1-2-4-21(16)25(22)30/h1-4,7-15,28H,5-6H2,(H,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50494284 (CHEMBL3087471) Show SMILES Cc1cc(F)c(NC(=O)c2ccsc2)cc1Nc1ccc2c(OCc3ccc(OC[C@H](O)CO)cc3C2=O)c1 |r| Show InChI InChI=1S/C29H25FN2O6S/c1-16-8-24(30)26(32-29(36)18-6-7-39-15-18)11-25(16)31-19-3-5-22-27(9-19)38-13-17-2-4-21(10-23(17)28(22)35)37-14-20(34)12-33/h2-11,15,20,31,33-34H,12-14H2,1H3,(H,32,36)/t20-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Competitive inhibition of p38alpha MAP kinase (unknown origin) in presence of 300 uM ATP				J Med Chem 56: 8561-78 (2013) Article DOI: 10.1021/jm401276h BindingDB Entry DOI: 10.7270/Q2Q81H2C
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50251985 (4-(4-(4-fluorophenyl)-2-(methylthio)-1H-imidazol-5...) Show SMILES CSc1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc(NC2CCOCC2)c1 Show InChI InChI=1S/C20H21FN4OS/c1-27-20-24-18(13-2-4-15(21)5-3-13)19(25-20)14-6-9-22-17(12-14)23-16-7-10-26-11-8-16/h2-6,9,12,16H,7-8,10-11H2,1H3,(H,22,23)(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Tu£bingen Curated by ChEMBL					Assay Description Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assay				J Med Chem 54: 3283-97 (2011) Article DOI: 10.1021/jm101623p BindingDB Entry DOI: 10.7270/Q2W959H4
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398153 (CHEMBL2177215) Show SMILES Fc1ccc(Nc2ccc3c(CCc4ccccc4C3=O)c2)cc1NC(=O)c1ccccc1 Show InChI InChI=1S/C28H21FN2O2/c29-25-15-13-22(17-26(25)31-28(33)19-7-2-1-3-8-19)30-21-12-14-24-20(16-21)11-10-18-6-4-5-9-23(18)27(24)32/h1-9,12-17,30H,10-11H2,(H,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50343505 ((S)-4-(4-(4-fluorophenyl)-2-(isopropylsulfinyl)-1H...) Show SMILES CC(C)Nc1cc(ccn1)-c1nc([nH]c1-c1ccc(F)cc1)[S@@](=O)C(C)C |r| Show InChI InChI=1S/C20H23FN4OS/c1-12(2)23-17-11-15(9-10-22-17)19-18(14-5-7-16(21)8-6-14)24-20(25-19)27(26)13(3)4/h5-13H,1-4H3,(H,22,23)(H,24,25)/t27-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Tu£bingen Curated by ChEMBL					Assay Description Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assay				J Med Chem 54: 3283-97 (2011) Article DOI: 10.1021/jm101623p BindingDB Entry DOI: 10.7270/Q2W959H4
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50503015 (CHEMBL4457174) Show SMILES Cc1nc(c([nH]1)-c1ccnc(NC(=O)C2CC2)c1)-c1ccc(F)c(C)c1 Show InChI InChI=1S/C20H19FN4O/c1-11-9-14(5-6-16(11)21)18-19(24-12(2)23-18)15-7-8-22-17(10-15)25-20(26)13-3-4-13/h5-10,13H,3-4H2,1-2H3,(H,23,24)(H,22,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard Karls Universit£t T£bingen Curated by ChEMBL					Assay Description Inhibition of P38alpha MAPK (unknown origin) by ADP-Glo assay				ACS Med Chem Lett 10: 1407-1414 (2019) Article DOI: 10.1021/acsmedchemlett.9b00177 BindingDB Entry DOI: 10.7270/Q2SQ93N5
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398458 (CHEMBL2179117) Show SMILES CS(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc2[nH]c(cc12)-c1ccccc1 Show InChI InChI=1S/C29H21FN4OS/c1-36(35)22-13-9-20(10-14-22)28-33-26(19-7-11-21(30)12-8-19)27(34-28)23-15-16-31-29-24(23)17-25(32-29)18-5-3-2-4-6-18/h2-17H,1H3,(H,31,32)(H,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
University of Tuebingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK				J Med Chem 55: 8429-39 (2012) Article DOI: 10.1021/jm300852w BindingDB Entry DOI: 10.7270/Q2765GGT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50494263 (CHEMBL3086680) Show SMILES OCCCOc1ccc2COc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C23H19F2NO4/c24-15-3-7-21(20(25)10-15)26-16-4-6-18-22(11-16)30-13-14-2-5-17(29-9-1-8-27)12-19(14)23(18)28/h2-7,10-12,26-27H,1,8-9,13H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Competitive inhibition of p38alpha MAP kinase (unknown origin) in presence of 100 uM ATP				J Med Chem 56: 8561-78 (2013) Article DOI: 10.1021/jm401276h BindingDB Entry DOI: 10.7270/Q2Q81H2C
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50330167 (2-(4-fluorophenyl)-N-(4-(4-(4-fluorophenyl)-2-(met...) Show SMILES CSc1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc(NC(=O)Cc2ccc(F)cc2)c1 Show InChI InChI=1S/C23H18F2N4OS/c1-31-23-28-21(15-4-8-18(25)9-5-15)22(29-23)16-10-11-26-19(13-16)27-20(30)12-14-2-6-17(24)7-3-14/h2-11,13H,12H2,1H3,(H,28,29)(H,26,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Tu£bingen Curated by ChEMBL					Assay Description Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assay				J Med Chem 54: 3283-97 (2011) Article DOI: 10.1021/jm101623p BindingDB Entry DOI: 10.7270/Q2W959H4
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398166 (CHEMBL2182071) Show SMILES O=C(Nc1cccc(Nc2ccc3c(CCc4ccccc4C3=O)c2)c1)c1ccoc1 Show InChI InChI=1S/C26H20N2O3/c29-25-23-7-2-1-4-17(23)8-9-18-14-22(10-11-24(18)25)27-20-5-3-6-21(15-20)28-26(30)19-12-13-31-16-19/h1-7,10-16,27H,8-9H2,(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398187 (CHEMBL2182089) Show SMILES Fc1ccc(Nc2ccc3c(OCc4ccccc4C3=O)c2)cc1NC(=O)c1ccsc1 Show InChI InChI=1S/C25H17FN2O3S/c26-21-8-6-17(11-22(21)28-25(30)16-9-10-32-14-16)27-18-5-7-20-23(12-18)31-13-15-3-1-2-4-19(15)24(20)29/h1-12,14,27H,13H2,(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398154 (CHEMBL2177214) Show SMILES Cc1ccc(Nc2ccc3c(CCc4ccccc4C3=O)c2)cc1NC(=O)c1ccccc1 Show InChI InChI=1S/C29H24N2O2/c1-19-11-14-24(18-27(19)31-29(33)21-8-3-2-4-9-21)30-23-15-16-26-22(17-23)13-12-20-7-5-6-10-25(20)28(26)32/h2-11,14-18,30H,12-13H2,1H3,(H,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398163 (CHEMBL2182074) Show SMILES O=C(Nc1cccc(Nc2ccc3c(CCc4ccccc4C3=O)c2)c1)c1ccsc1 Show InChI InChI=1S/C26H20N2O2S/c29-25-23-7-2-1-4-17(23)8-9-18-14-22(10-11-24(18)25)27-20-5-3-6-21(15-20)28-26(30)19-12-13-31-16-19/h1-7,10-16,27H,8-9H2,(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50494273 (CHEMBL3087473) Show SMILES Fc1ccc(NC(=O)c2ccccc2)cc1Nc1ccc2c(OCc3c(OCCN4CCOCC4)cccc3C2=O)c1 Show InChI InChI=1S/C33H30FN3O5/c34-28-12-10-23(36-33(39)22-5-2-1-3-6-22)19-29(28)35-24-9-11-26-31(20-24)42-21-27-25(32(26)38)7-4-8-30(27)41-18-15-37-13-16-40-17-14-37/h1-12,19-20,35H,13-18,21H2,(H,36,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Competitive inhibition of p38alpha MAP kinase (unknown origin) in presence of 100 uM ATP				J Med Chem 56: 8561-78 (2013) Article DOI: 10.1021/jm401276h BindingDB Entry DOI: 10.7270/Q2Q81H2C
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50343502 ((R)-4-(4-(4-fluorophenyl)-2-(methylsulfinyl)-1H-im...) Show SMILES C[S@@](=O)c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc(NC2CCOCC2)c1 |r| Show InChI InChI=1S/C20H21FN4O2S/c1-28(26)20-24-18(13-2-4-15(21)5-3-13)19(25-20)14-6-9-22-17(12-14)23-16-7-10-27-11-8-16/h2-6,9,12,16H,7-8,10-11H2,1H3,(H,22,23)(H,24,25)/t28-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Tu£bingen Curated by ChEMBL					Assay Description Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assay				J Med Chem 54: 3283-97 (2011) Article DOI: 10.1021/jm101623p BindingDB Entry DOI: 10.7270/Q2W959H4
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50343504 ((R)-N-cyclohexyl-4-(4-(4-fluorophenyl)-2-(isopropy...) Show SMILES CC(C)[S@@](=O)c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc(NC2CCCCC2)c1 |r| Show InChI InChI=1S/C23H27FN4OS/c1-15(2)30(29)23-27-21(16-8-10-18(24)11-9-16)22(28-23)17-12-13-25-20(14-17)26-19-6-4-3-5-7-19/h8-15,19H,3-7H2,1-2H3,(H,25,26)(H,27,28)/t30-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Tu£bingen Curated by ChEMBL					Assay Description Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assay				J Med Chem 54: 3283-97 (2011) Article DOI: 10.1021/jm101623p BindingDB Entry DOI: 10.7270/Q2W959H4
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398457 (CHEMBL2179118) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc2[nH]c(cc12)-c1ccccc1 Show InChI InChI=1S/C29H21FN4O2S/c1-37(35,36)22-13-9-20(10-14-22)28-33-26(19-7-11-21(30)12-8-19)27(34-28)23-15-16-31-29-24(23)17-25(32-29)18-5-3-2-4-6-18/h2-17H,1H3,(H,31,32)(H,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
University of Tuebingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK				J Med Chem 55: 8429-39 (2012) Article DOI: 10.1021/jm300852w BindingDB Entry DOI: 10.7270/Q2765GGT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398188 (CHEMBL2182088) Show SMILES Cc1ccc(Nc2ccc3c(OCc4ccccc4C3=O)c2)cc1NC(=O)c1ccsc1 Show InChI InChI=1S/C26H20N2O3S/c1-16-6-7-19(12-23(16)28-26(30)18-10-11-32-15-18)27-20-8-9-22-24(13-20)31-14-17-4-2-3-5-21(17)25(22)29/h2-13,15,27H,14H2,1H3,(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50502999 (CHEMBL4561980) Show SMILES Cc1nc(c([nH]1)-c1ccnc(NC(=O)C2CC2)c1)-c1ccccc1O Show InChI InChI=1S/C19H18N4O2/c1-11-21-17(18(22-11)14-4-2-3-5-15(14)24)13-8-9-20-16(10-13)23-19(25)12-6-7-12/h2-5,8-10,12,24H,6-7H2,1H3,(H,21,22)(H,20,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard Karls Universit£t T£bingen Curated by ChEMBL					Assay Description Inhibition of GSK3beta (unknown origin) by ADP-Glo assay				ACS Med Chem Lett 10: 1407-1414 (2019) Article DOI: 10.1021/acsmedchemlett.9b00177 BindingDB Entry DOI: 10.7270/Q2SQ93N5
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50343489 (CHEMBL1773502 | N-Cyclohexyl-4-(4-(4-fluorophenyl)...) Show SMILES CC(C)Sc1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc(NC2CCCCC2)c1 Show InChI InChI=1S/C23H27FN4S/c1-15(2)29-23-27-21(16-8-10-18(24)11-9-16)22(28-23)17-12-13-25-20(14-17)26-19-6-4-3-5-7-19/h8-15,19H,3-7H2,1-2H3,(H,25,26)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Tu£bingen Curated by ChEMBL					Assay Description Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assay				J Med Chem 54: 3283-97 (2011) Article DOI: 10.1021/jm101623p BindingDB Entry DOI: 10.7270/Q2W959H4
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50343493 ((R)-4-(4-(4-fluorophenyl)-2-(methylsulfinyl)-1H-im...) Show SMILES CC(C)Nc1cc(ccn1)-c1nc([nH]c1-c1ccc(F)cc1)[S@@](C)=O |r| Show InChI InChI=1S/C18H19FN4OS/c1-11(2)21-15-10-13(8-9-20-15)17-16(22-18(23-17)25(3)24)12-4-6-14(19)7-5-12/h4-11H,1-3H3,(H,20,21)(H,22,23)/t25-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Tu£bingen Curated by ChEMBL					Assay Description Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assay				J Med Chem 54: 3283-97 (2011) Article DOI: 10.1021/jm101623p BindingDB Entry DOI: 10.7270/Q2W959H4
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50343487 ((S)-4-(4-(4-fluorophenyl)-2-(methylsulfinyl)-1H-im...) Show SMILES C[S@](=O)c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc(NC2CCOCC2)c1 |r| Show InChI InChI=1S/C20H21FN4O2S/c1-28(26)20-24-18(13-2-4-15(21)5-3-13)19(25-20)14-6-9-22-17(12-14)23-16-7-10-27-11-8-16/h2-6,9,12,16H,7-8,10-11H2,1H3,(H,22,23)(H,24,25)/t28-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Tu£bingen Curated by ChEMBL					Assay Description Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assay				J Med Chem 54: 3283-97 (2011) Article DOI: 10.1021/jm101623p BindingDB Entry DOI: 10.7270/Q2W959H4
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398150 (CHEMBL2177106) Show SMILES Fc1ccc(NC(=O)c2ccccc2)cc1Nc1ccc2c(CCCCC2=O)c1 Show InChI InChI=1S/C24H21FN2O2/c25-21-13-11-19(27-24(29)16-6-2-1-3-7-16)15-22(21)26-18-10-12-20-17(14-18)8-4-5-9-23(20)28/h1-3,6-7,10-15,26H,4-5,8-9H2,(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398186 (CHEMBL2182090) Show SMILES Cc1cc(F)c(NC(=O)c2ccsc2)cc1Nc1ccc2c(OCc3ccccc3C2=O)c1 Show InChI InChI=1S/C26H19FN2O3S/c1-15-10-21(27)23(29-26(31)17-8-9-33-14-17)12-22(15)28-18-6-7-20-24(11-18)32-13-16-4-2-3-5-19(16)25(20)30/h2-12,14,28H,13H2,1H3,(H,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398194 (CHEMBL2182082) Show SMILES O=C(Nc1cccc(Nc2ccc3c(CCCCC3=O)c2)c1)c1ccsc1 Show InChI InChI=1S/C22H20N2O2S/c25-21-7-2-1-4-15-12-19(8-9-20(15)21)23-17-5-3-6-18(13-17)24-22(26)16-10-11-27-14-16/h3,5-6,8-14,23H,1-2,4,7H2,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398132 (CHEMBL2182099) Show SMILES COc1cccc(c1)C(=O)Nc1cccc(Nc2ccc3c(CCc4ccccc4C3=O)c2)c1 Show InChI InChI=1S/C29H24N2O3/c1-34-25-10-4-7-21(17-25)29(33)31-23-9-5-8-22(18-23)30-24-14-15-27-20(16-24)13-12-19-6-2-3-11-26(19)28(27)32/h2-11,14-18,30H,12-13H2,1H3,(H,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50392172 (CHEMBL2152941) Show SMILES OCCCOc1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C24H21F2NO3/c25-17-5-9-23(22(26)13-17)27-18-6-8-20-16(12-18)3-2-15-4-7-19(30-11-1-10-28)14-21(15)24(20)29/h4-9,12-14,27-28H,1-3,10-11H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Competitive inhibition of p38alpha MAP kinase (unknown origin) in presence of 100 uM ATP				J Med Chem 56: 8561-78 (2013) Article DOI: 10.1021/jm401276h BindingDB Entry DOI: 10.7270/Q2Q81H2C
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50503022 (CHEMBL4445449) Show SMILES Cc1nc([nH]c1-c1ccnc(NC(=O)C2CC2)c1)C(N)=O Show InChI InChI=1S/C14H15N5O2/c1-7-11(19-13(17-7)12(15)20)9-4-5-16-10(6-9)18-14(21)8-2-3-8/h4-6,8H,2-3H2,1H3,(H2,15,20)(H,17,19)(H,16,18,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard Karls Universit£t T£bingen Curated by ChEMBL					Assay Description Inhibition of GSK3beta (unknown origin) by ADP-Glo assay				ACS Med Chem Lett 10: 1407-1414 (2019) Article DOI: 10.1021/acsmedchemlett.9b00177 BindingDB Entry DOI: 10.7270/Q2SQ93N5
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398151 (CHEMBL2177217) Show SMILES Cc1ccc(NC(=O)c2ccccc2)cc1Nc1ccc2c(CCCCC2=O)c1 Show InChI InChI=1S/C25H24N2O2/c1-17-11-12-21(27-25(29)18-7-3-2-4-8-18)16-23(17)26-20-13-14-22-19(15-20)9-5-6-10-24(22)28/h2-4,7-8,11-16,26H,5-6,9-10H2,1H3,(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398155 (CHEMBL2177213) Show SMILES Fc1ccc(NC(=O)c2ccccc2)cc1Nc1ccc2c(CCc3ccccc3C2=O)c1 Show InChI InChI=1S/C28H21FN2O2/c29-25-15-13-22(31-28(33)19-7-2-1-3-8-19)17-26(25)30-21-12-14-24-20(16-21)11-10-18-6-4-5-9-23(18)27(24)32/h1-9,12-17,30H,10-11H2,(H,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50494258 (CHEMBL3086675) Show SMILES OC[C@@H](O)COc1ccc2COc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 |r| Show InChI InChI=1S/C23H19F2NO5/c24-14-2-6-21(20(25)7-14)26-15-3-5-18-22(8-15)31-11-13-1-4-17(9-19(13)23(18)29)30-12-16(28)10-27/h1-9,16,26-28H,10-12H2/t16-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Competitive inhibition of p38alpha MAP kinase (unknown origin) in presence of 100 uM ATP				J Med Chem 56: 8561-78 (2013) Article DOI: 10.1021/jm401276h BindingDB Entry DOI: 10.7270/Q2Q81H2C
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM13336 (4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...) Show SMILES CS(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C21H16FN3OS/c1-27(26)18-8-4-16(5-9-18)21-24-19(14-2-6-17(22)7-3-14)20(25-21)15-10-12-23-13-11-15/h2-13H,1H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Tu£bingen Curated by ChEMBL					Assay Description Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assay				J Med Chem 54: 3283-97 (2011) Article DOI: 10.1021/jm101623p BindingDB Entry DOI: 10.7270/Q2W959H4
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398464 (CHEMBL2179115) Show SMILES Fc1ccc(cc1)-c1[nH]c(nc1-c1ccnc2[nH]c(cc12)C1CCCCC1)-c1ccccc1 Show InChI InChI=1S/C28H25FN4/c29-21-13-11-19(12-14-21)25-26(33-27(32-25)20-9-5-2-6-10-20)22-15-16-30-28-23(22)17-24(31-28)18-7-3-1-4-8-18/h2,5-6,9-18H,1,3-4,7-8H2,(H,30,31)(H,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
University of Tuebingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK				J Med Chem 55: 8429-39 (2012) Article DOI: 10.1021/jm300852w BindingDB Entry DOI: 10.7270/Q2765GGT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398173 (CHEMBL2177209) Show SMILES Cc1cccc(c1)C(=O)Nc1cccc(Nc2ccc3c(OCc4ccccc4C3=O)c2)c1 Show InChI InChI=1S/C28H22N2O3/c1-18-6-4-8-19(14-18)28(32)30-22-10-5-9-21(15-22)29-23-12-13-25-26(16-23)33-17-20-7-2-3-11-24(20)27(25)31/h2-16,29H,17H2,1H3,(H,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398466 (CHEMBL2179128) Show SMILES Fc1ccc(cc1)-c1[nH]c(nc1-c1ccnc2[nH]c(cc12)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C28H19FN4/c29-21-13-11-19(12-14-21)25-26(33-27(32-25)20-9-5-2-6-10-20)22-15-16-30-28-23(22)17-24(31-28)18-7-3-1-4-8-18/h1-17H,(H,30,31)(H,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
University of Tuebingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK				J Med Chem 55: 8429-39 (2012) Article DOI: 10.1021/jm300852w BindingDB Entry DOI: 10.7270/Q2765GGT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50502996 (CHEMBL4451444) Show SMILES OCc1nc(c([nH]1)-c1ccnc(NC(=O)C2CC2)c1)-c1ccc(F)cc1 Show InChI InChI=1S/C19H17FN4O2/c20-14-5-3-11(4-6-14)17-18(23-16(10-25)22-17)13-7-8-21-15(9-13)24-19(26)12-1-2-12/h3-9,12,25H,1-2,10H2,(H,22,23)(H,21,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard Karls Universit£t T£bingen Curated by ChEMBL					Assay Description Inhibition of P38alpha MAPK (unknown origin) by ADP-Glo assay				ACS Med Chem Lett 10: 1407-1414 (2019) Article DOI: 10.1021/acsmedchemlett.9b00177 BindingDB Entry DOI: 10.7270/Q2SQ93N5
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 447 total )  |  Next  |  Last  >>

Jump to: