Compile Data Set for Download or QSAR

Found 687 hits with Last Name = 'hübsch' and Initial = 'w'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302404 (US9598416, Example 50) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCN(C)CC2)cn2ncnc(N)c12 Show InChI InChI=1S/C22H26N6OS/c1-14-8-15-10-18(30-21(15)17(9-14)29-3)19-16(11-27-6-4-26(2)5-7-27)12-28-20(19)22(23)24-13-25-28/h8-10,12-13H,4-7,11H2,1-3H3,(H2,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302362 (6-[(2-Aminoethoxy)methyl]-5-(7-methoxy-5-methyl-1-...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(COCCN)cn2ncnc(N)c12 Show InChI InChI=1S/C19H21N5O2S/c1-11-5-12-7-15(27-18(12)14(6-11)25-2)16-13(9-26-4-3-20)8-24-17(16)19(21)22-10-23-24/h5-8,10H,3-4,9,20H2,1-2H3,(H2,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302363 (N-{[4-Amino-5-(7-methoxy-5-methyl-1-benzothiophen-...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CNC(C)=O)cn2ncnc(N)c12 Show InChI InChI=1S/C19H19N5O2S/c1-10-4-12-6-15(27-18(12)14(5-10)26-3)16-13(7-21-11(2)25)8-24-17(16)19(20)22-9-23-24/h4-6,8-9H,7H2,1-3H3,(H,21,25)(H2,20,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302362 (6-[(2-Aminoethoxy)methyl]-5-(7-methoxy-5-methyl-1-...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(COCCN)cn2ncnc(N)c12 Show InChI InChI=1S/C19H21N5O2S/c1-11-5-12-7-15(27-18(12)14(6-11)25-2)16-13(9-26-4-3-20)8-24-17(16)19(21)22-10-23-24/h5-8,10H,3-4,9,20H2,1-2H3,(H2,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM194899 (US9206184, 80) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCNC(=O)C2)c(Cl)n2ncnc(N)c12 Show InChI InChI=1S/C21H21ClN6O2S/c1-11-5-12-7-15(31-19(12)14(6-11)30-2)17-13(8-27-4-3-24-16(29)9-27)20(22)28-18(17)21(23)25-10-26-28/h5-7,10H,3-4,8-9H2,1-2H3,(H,24,29)(H2,23,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLECTUAL PROPERTY GmbH US Patent					Assay Description For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...				US Patent US9206184 (2015) BindingDB Entry DOI: 10.7270/Q2SN07SH
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302404 (US9598416, Example 50) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCN(C)CC2)cn2ncnc(N)c12 Show InChI InChI=1S/C22H26N6OS/c1-14-8-15-10-18(30-21(15)17(9-14)29-3)19-16(11-27-6-4-26(2)5-7-27)12-28-20(19)22(23)24-13-25-28/h8-10,12-13H,4-7,11H2,1-3H3,(H2,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302385 (4-{[4-Amino-5-(5-chloro-7-methoxy-1-benzothiophen-...) Show SMILES COc1cc(Cl)cc2cc(sc12)-c1c(CN2CCNC(=O)C2)cn2ncnc(N)c12 Show InChI InChI=1S/C20H19ClN6O2S/c1-29-14-6-13(21)4-11-5-15(30-19(11)14)17-12(7-26-3-2-23-16(28)9-26)8-27-18(17)20(22)24-10-25-27/h4-6,8,10H,2-3,7,9H2,1H3,(H,23,28)(H2,22,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302379 (5-(7-Methoxy-5-methyl-1-benzothiophen-2-yl)-6-(pip...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCNCC2)cn2ncnc(N)c12 Show InChI InChI=1S/C21H24N6OS/c1-13-7-14-9-17(29-20(14)16(8-13)28-2)18-15(10-26-5-3-23-4-6-26)11-27-19(18)21(22)24-12-25-27/h7-9,11-12,23H,3-6,10H2,1-2H3,(H2,22,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302365 (4-{[4-Amino-5-(7-methoxy-5-methyl-1-benzothiophen-...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCNC(=O)C2)cn2ncnc(N)c12 Show InChI InChI=1S/C21H22N6O2S/c1-12-5-13-7-16(30-20(13)15(6-12)29-2)18-14(8-26-4-3-23-17(28)10-26)9-27-19(18)21(22)24-11-25-27/h5-7,9,11H,3-4,8,10H2,1-2H3,(H,23,28)(H2,22,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM194880 (US9206184, 61) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(-c2cnco2)c(CN2CCNCC2)n2ncnc(N)c12 Show InChI InChI=1S/C24H25N7O2S/c1-14-7-15-9-19(34-23(15)17(8-14)32-2)21-20(18-10-27-13-33-18)16(11-30-5-3-26-4-6-30)31-22(21)24(25)28-12-29-31/h7-10,12-13,26H,3-6,11H2,1-2H3,(H2,25,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLECTUAL PROPERTY GmbH US Patent					Assay Description For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...				US Patent US9206184 (2015) BindingDB Entry DOI: 10.7270/Q2SN07SH
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302420 (US9598416, Example 66) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CC[C@@H](C2)N(C)C)cn2ncnc(N)c12 |r| Show InChI InChI=1S/C23H28N6OS/c1-14-7-15-9-19(31-22(15)18(8-14)30-4)20-16(10-28-6-5-17(12-28)27(2)3)11-29-21(20)23(24)25-13-26-29/h7-9,11,13,17H,5-6,10,12H2,1-4H3,(H2,24,25,26)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM194900 (US9206184, 81 | US9206184, 82) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CNCC(C)(C)O)c(Cl)n2ncnc(N)c12 Show InChI InChI=1S/C21H24ClN5O2S/c1-11-5-12-7-15(30-18(12)14(6-11)29-4)16-13(8-24-9-21(2,3)28)19(22)27-17(16)20(23)25-10-26-27/h5-7,10,24,28H,8-9H2,1-4H3,(H2,23,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLECTUAL PROPERTY GmbH US Patent					Assay Description For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...				US Patent US9206184 (2015) BindingDB Entry DOI: 10.7270/Q2SN07SH
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM194837 (US9206184, 18 | US9206184, 19) Show SMILES CCOCc1c(CN2CCNCC2)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1 Show InChI InChI=1S/C24H30N6O2S/c1-4-32-13-17-18(12-29-7-5-26-6-8-29)30-22(24(25)27-14-28-30)21(17)20-11-16-9-15(2)10-19(31-3)23(16)33-20/h9-11,14,26H,4-8,12-13H2,1-3H3,(H2,25,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLECTUAL PROPERTY GmbH US Patent					Assay Description For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...				US Patent US9206184 (2015) BindingDB Entry DOI: 10.7270/Q2SN07SH
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302381 ((3S)-3-({[4-Amino-5-(7-methoxy-5-methyl-1-benzothi...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN[C@H]2CCNC2=O)cn2ncnc(N)c12 |r| Show InChI InChI=1S/C21H22N6O2S/c1-11-5-12-7-16(30-19(12)15(6-11)29-2)17-13(8-24-14-3-4-23-21(14)28)9-27-18(17)20(22)25-10-26-27/h5-7,9-10,14,24H,3-4,8H2,1-2H3,(H,23,28)(H2,22,25,26)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302385 (4-{[4-Amino-5-(5-chloro-7-methoxy-1-benzothiophen-...) Show SMILES COc1cc(Cl)cc2cc(sc12)-c1c(CN2CCNC(=O)C2)cn2ncnc(N)c12 Show InChI InChI=1S/C20H19ClN6O2S/c1-29-14-6-13(21)4-11-5-15(30-19(11)14)17-12(7-26-3-2-23-16(28)9-26)8-27-18(17)20(22)24-10-25-27/h4-6,8,10H,2-3,7,9H2,1H3,(H,23,28)(H2,22,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302379 (5-(7-Methoxy-5-methyl-1-benzothiophen-2-yl)-6-(pip...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCNCC2)cn2ncnc(N)c12 Show InChI InChI=1S/C21H24N6OS/c1-13-7-14-9-17(29-20(14)16(8-13)28-2)18-15(10-26-5-3-23-4-6-26)11-27-19(18)21(22)24-12-25-27/h7-9,11-12,23H,3-6,10H2,1-2H3,(H2,22,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302421 (US9598416, Example 67) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCCC(C2)N(C)C)cn2ncnc(N)c12 Show InChI InChI=1S/C24H30N6OS/c1-15-8-16-10-20(32-23(16)19(9-15)31-4)21-17(12-30-22(21)24(25)26-14-27-30)11-29-7-5-6-18(13-29)28(2)3/h8-10,12,14,18H,5-7,11,13H2,1-4H3,(H2,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302419 (US9598416, Example 65) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CC[C@H](C2)N(C)C)cn2ncnc(N)c12 |r| Show InChI InChI=1S/C23H28N6OS/c1-14-7-15-9-19(31-22(15)18(8-14)30-4)20-16(10-28-6-5-17(12-28)27(2)3)11-29-21(20)23(24)25-13-26-29/h7-9,11,13,17H,5-6,10,12H2,1-4H3,(H2,24,25,26)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302363 (N-{[4-Amino-5-(7-methoxy-5-methyl-1-benzothiophen-...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CNC(C)=O)cn2ncnc(N)c12 Show InChI InChI=1S/C19H19N5O2S/c1-10-4-12-6-15(27-18(12)14(5-10)26-3)16-13(7-21-11(2)25)8-24-17(16)19(20)22-9-23-24/h4-6,8-9H,7H2,1-3H3,(H,21,25)(H2,20,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM194844 (US9206184, 25) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(COCC2CC2)c(CN2CCNCC2)n2ncnc(N)c12 Show InChI InChI=1S/C26H32N6O2S/c1-16-9-18-11-22(35-25(18)21(10-16)33-2)23-19(14-34-13-17-3-4-17)20(12-31-7-5-28-6-8-31)32-24(23)26(27)29-15-30-32/h9-11,15,17,28H,3-8,12-14H2,1-2H3,(H2,27,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLECTUAL PROPERTY GmbH US Patent					Assay Description For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...				US Patent US9206184 (2015) BindingDB Entry DOI: 10.7270/Q2SN07SH
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM194837 (US9206184, 18 | US9206184, 19) Show SMILES CCOCc1c(CN2CCNCC2)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1 Show InChI InChI=1S/C24H30N6O2S/c1-4-32-13-17-18(12-29-7-5-26-6-8-29)30-22(24(25)27-14-28-30)21(17)20-11-16-9-15(2)10-19(31-3)23(16)33-20/h9-11,14,26H,4-8,12-13H2,1-3H3,(H2,25,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLECTUAL PROPERTY GmbH US Patent					Assay Description For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...				US Patent US9206184 (2015) BindingDB Entry DOI: 10.7270/Q2SN07SH
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302419 (US9598416, Example 65) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CC[C@H](C2)N(C)C)cn2ncnc(N)c12 |r| Show InChI InChI=1S/C23H28N6OS/c1-14-7-15-9-19(31-22(15)18(8-14)30-4)20-16(10-28-6-5-17(12-28)27(2)3)11-29-21(20)23(24)25-13-26-29/h7-9,11,13,17H,5-6,10,12H2,1-4H3,(H2,24,25,26)/t17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM194891 (US9206184, 72) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CNC(C)=O)c(CNC(C)=O)n2ncnc(N)c12 Show InChI InChI=1S/C22H24N6O3S/c1-11-5-14-7-18(32-21(14)17(6-11)31-4)19-15(8-24-12(2)29)16(9-25-13(3)30)28-20(19)22(23)26-10-27-28/h5-7,10H,8-9H2,1-4H3,(H,24,29)(H,25,30)(H2,23,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLECTUAL PROPERTY GmbH US Patent					Assay Description For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...				US Patent US9206184 (2015) BindingDB Entry DOI: 10.7270/Q2SN07SH
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302405 (US9598416, Example 51) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCCCC2)cn2ncnc(N)c12 Show InChI InChI=1S/C22H25N5OS/c1-14-8-15-10-18(29-21(15)17(9-14)28-2)19-16(11-26-6-4-3-5-7-26)12-27-20(19)22(23)24-13-25-27/h8-10,12-13H,3-7,11H2,1-2H3,(H2,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302422 (US9598416, Example 68) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCCN(C)CC2)cn2ncnc(N)c12 Show InChI InChI=1S/C23H28N6OS/c1-15-9-16-11-19(31-22(16)18(10-15)30-3)20-17(12-28-6-4-5-27(2)7-8-28)13-29-21(20)23(24)25-14-26-29/h9-11,13-14H,4-8,12H2,1-3H3,(H2,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302368 (N2-{[4-Amino-5-(7-methoxy-5-methyl-1-benzothiophen...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN(C)CC(N)=O)cn2ncnc(N)c12 Show InChI InChI=1S/C20H22N6O2S/c1-11-4-12-6-15(29-19(12)14(5-11)28-3)17-13(7-25(2)9-16(21)27)8-26-18(17)20(22)23-10-24-26/h4-6,8,10H,7,9H2,1-3H3,(H2,21,27)(H2,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302381 ((3S)-3-({[4-Amino-5-(7-methoxy-5-methyl-1-benzothi...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN[C@H]2CCNC2=O)cn2ncnc(N)c12 |r| Show InChI InChI=1S/C21H22N6O2S/c1-11-5-12-7-16(30-19(12)15(6-11)29-2)17-13(8-24-14-3-4-23-21(14)28)9-27-18(17)20(22)25-10-26-27/h5-7,9-10,14,24H,3-4,8H2,1-2H3,(H,23,28)(H2,22,25,26)/t14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM194845 (US9206184, 26) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(COC2CCC2)c(CN2CCNCC2)n2ncnc(N)c12 Show InChI InChI=1S/C26H32N6O2S/c1-16-10-17-12-22(35-25(17)21(11-16)33-2)23-19(14-34-18-4-3-5-18)20(13-31-8-6-28-7-9-31)32-24(23)26(27)29-15-30-32/h10-12,15,18,28H,3-9,13-14H2,1-2H3,(H2,27,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLECTUAL PROPERTY GmbH US Patent					Assay Description For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...				US Patent US9206184 (2015) BindingDB Entry DOI: 10.7270/Q2SN07SH
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM194841 (US9206184, 22) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(COCCO)c(CN2CCNCC2)n2ncnc(N)c12 Show InChI InChI=1S/C24H30N6O3S/c1-15-9-16-11-20(34-23(16)19(10-15)32-2)21-17(13-33-8-7-31)18(12-29-5-3-26-4-6-29)30-22(21)24(25)27-14-28-30/h9-11,14,26,31H,3-8,12-13H2,1-2H3,(H2,25,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLECTUAL PROPERTY GmbH US Patent					Assay Description For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...				US Patent US9206184 (2015) BindingDB Entry DOI: 10.7270/Q2SN07SH
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM194836 (US9206184, 17) Show SMILES COCc1c(CN2CCNCC2)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1 Show InChI InChI=1S/C23H28N6O2S/c1-14-8-15-10-19(32-22(15)18(9-14)31-3)20-16(12-30-2)17(11-28-6-4-25-5-7-28)29-21(20)23(24)26-13-27-29/h8-10,13,25H,4-7,11-12H2,1-3H3,(H2,24,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLECTUAL PROPERTY GmbH US Patent					Assay Description For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...				US Patent US9206184 (2015) BindingDB Entry DOI: 10.7270/Q2SN07SH
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM194880 (US9206184, 61) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(-c2cnco2)c(CN2CCNCC2)n2ncnc(N)c12 Show InChI InChI=1S/C24H25N7O2S/c1-14-7-15-9-19(34-23(15)17(8-14)32-2)21-20(18-10-27-13-33-18)16(11-30-5-3-26-4-6-30)31-22(21)24(25)28-12-29-31/h7-10,12-13,26H,3-6,11H2,1-2H3,(H2,25,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLECTUAL PROPERTY GmbH US Patent					Assay Description For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...				US Patent US9206184 (2015) BindingDB Entry DOI: 10.7270/Q2SN07SH
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302421 (US9598416, Example 67) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCCC(C2)N(C)C)cn2ncnc(N)c12 Show InChI InChI=1S/C24H30N6OS/c1-15-8-16-10-20(32-23(16)19(9-15)31-4)21-17(12-30-22(21)24(25)26-14-27-30)11-29-7-5-6-18(13-29)28(2)3/h8-10,12,14,18H,5-7,11,13H2,1-4H3,(H2,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM194834 (US9206184, 15) Show SMILES CCOCc1c(CN2CC[C@](C)(N)C2)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1 |r| Show InChI InChI=1S/C25H32N6O2S/c1-5-33-12-17-18(11-30-7-6-25(3,27)13-30)31-22(24(26)28-14-29-31)21(17)20-10-16-8-15(2)9-19(32-4)23(16)34-20/h8-10,14H,5-7,11-13,27H2,1-4H3,(H2,26,28,29)/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLECTUAL PROPERTY GmbH US Patent					Assay Description For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...				US Patent US9206184 (2015) BindingDB Entry DOI: 10.7270/Q2SN07SH
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM194883 (US9206184, 64) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CNC(C)=O)c(CN2CCNCC2)n2ncnc(N)c12 Show InChI InChI=1S/C24H29N7O2S/c1-14-8-16-10-20(34-23(16)19(9-14)33-3)21-17(11-27-15(2)32)18(12-30-6-4-26-5-7-30)31-22(21)24(25)28-13-29-31/h8-10,13,26H,4-7,11-12H2,1-3H3,(H,27,32)(H2,25,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLECTUAL PROPERTY GmbH US Patent					Assay Description For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...				US Patent US9206184 (2015) BindingDB Entry DOI: 10.7270/Q2SN07SH
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302401 (US9598416, Example 47) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCCC2)cn2ncnc(N)c12 Show InChI InChI=1S/C21H23N5OS/c1-13-7-14-9-17(28-20(14)16(8-13)27-2)18-15(10-25-5-3-4-6-25)11-26-19(18)21(22)23-12-24-26/h7-9,11-12H,3-6,10H2,1-2H3,(H2,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM194852 (US9206184, 33) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(COCC(N)=O)c(CN2CCNCC2)n2ncnc(N)c12 Show InChI InChI=1S/C24H29N7O3S/c1-14-7-15-9-19(35-23(15)18(8-14)33-2)21-16(11-34-12-20(25)32)17(10-30-5-3-27-4-6-30)31-22(21)24(26)28-13-29-31/h7-9,13,27H,3-6,10-12H2,1-2H3,(H2,25,32)(H2,26,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLECTUAL PROPERTY GmbH US Patent					Assay Description For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...				US Patent US9206184 (2015) BindingDB Entry DOI: 10.7270/Q2SN07SH
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302364 (2-({[4-Amino-5-(7-methoxy-5-methyl-1-benzothiophen...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CNCCO)cn2ncnc(N)c12 Show InChI InChI=1S/C19H21N5O2S/c1-11-5-12-7-15(27-18(12)14(6-11)26-2)16-13(8-21-3-4-25)9-24-17(16)19(20)22-10-23-24/h5-7,9-10,21,25H,3-4,8H2,1-2H3,(H2,20,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM194834 (US9206184, 15) Show SMILES CCOCc1c(CN2CC[C@](C)(N)C2)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1 |r| Show InChI InChI=1S/C25H32N6O2S/c1-5-33-12-17-18(11-30-7-6-25(3,27)13-30)31-22(24(26)28-14-29-31)21(17)20-10-16-8-15(2)9-19(32-4)23(16)34-20/h8-10,14H,5-7,11-13,27H2,1-4H3,(H2,26,28,29)/t25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLECTUAL PROPERTY GmbH US Patent					Assay Description For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...				US Patent US9206184 (2015) BindingDB Entry DOI: 10.7270/Q2SN07SH
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302420 (US9598416, Example 66) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CC[C@@H](C2)N(C)C)cn2ncnc(N)c12 |r| Show InChI InChI=1S/C23H28N6OS/c1-14-7-15-9-19(31-22(15)18(8-14)30-4)20-16(10-28-6-5-17(12-28)27(2)3)11-29-21(20)23(24)25-13-26-29/h7-9,11,13,17H,5-6,10,12H2,1-4H3,(H2,24,25,26)/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302365 (4-{[4-Amino-5-(7-methoxy-5-methyl-1-benzothiophen-...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCNC(=O)C2)cn2ncnc(N)c12 Show InChI InChI=1S/C21H22N6O2S/c1-12-5-13-7-16(30-20(13)15(6-12)29-2)18-14(8-26-4-3-23-17(28)10-26)9-27-19(18)21(22)24-11-25-27/h5-7,9,11H,3-4,8,10H2,1-2H3,(H,23,28)(H2,22,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 [400-80]/Glutathione S-transferase P (Homo sapiens (Human))	BDBM255620 (US9475815, 5) Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN2CC[C@](C)(N)C2)n2ncnc(N)c12 |r| Show InChI InChI=1S/C22H26N6OS/c1-13-6-14-8-18(30-20(14)17(7-13)29-3)16-9-15(10-27-5-4-22(2,24)11-27)28-19(16)21(23)25-12-26-28/h6-9,12H,4-5,10-11,24H2,1-3H3,(H2,23,25,26)/t22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLETUAL PROPERTY GMBH US Patent					Assay Description A recombinant tagged FGFR-1 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...				US Patent US9475815 (2016) BindingDB Entry DOI: 10.7270/Q2862FC7
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302418 (US9598416, Example 64) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCC(CC2)C(N)=O)cn2ncnc(N)c12 Show InChI InChI=1S/C23H26N6O2S/c1-13-7-15-9-18(32-21(15)17(8-13)31-2)19-16(11-29-20(19)22(24)26-12-27-29)10-28-5-3-14(4-6-28)23(25)30/h7-9,11-12,14H,3-6,10H2,1-2H3,(H2,25,30)(H2,24,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM194858 (US9206184, 39) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CNCCO)c(CN2CCNCC2)n2ncnc(N)c12 Show InChI InChI=1S/C24H31N7O2S/c1-15-9-16-11-20(34-23(16)19(10-15)33-2)21-17(12-27-5-8-32)18(13-30-6-3-26-4-7-30)31-22(21)24(25)28-14-29-31/h9-11,14,26-27,32H,3-8,12-13H2,1-2H3,(H2,25,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLECTUAL PROPERTY GmbH US Patent					Assay Description For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...				US Patent US9206184 (2015) BindingDB Entry DOI: 10.7270/Q2SN07SH
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302400 (US9598416, Example 46) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN(C)CCC#N)cn2ncnc(N)c12 Show InChI InChI=1S/C21H22N6OS/c1-13-7-14-9-17(29-20(14)16(8-13)28-3)18-15(10-26(2)6-4-5-22)11-27-19(18)21(23)24-12-25-27/h7-9,11-12H,4,6,10H2,1-3H3,(H2,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM194843 (US9206184, 24) Show SMILES CCCOCc1c(CN2CCNCC2)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1 Show InChI InChI=1S/C25H32N6O2S/c1-4-9-33-14-18-19(13-30-7-5-27-6-8-30)31-23(25(26)28-15-29-31)22(18)21-12-17-10-16(2)11-20(32-3)24(17)34-21/h10-12,15,27H,4-9,13-14H2,1-3H3,(H2,26,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLECTUAL PROPERTY GmbH US Patent					Assay Description For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...				US Patent US9206184 (2015) BindingDB Entry DOI: 10.7270/Q2SN07SH
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM194846 (US9206184, 27) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(COC(C)C)c(CN2CCNCC2)n2ncnc(N)c12 Show InChI InChI=1S/C25H32N6O2S/c1-15(2)33-13-18-19(12-30-7-5-27-6-8-30)31-23(25(26)28-14-29-31)22(18)21-11-17-9-16(3)10-20(32-4)24(17)34-21/h9-11,14-15,27H,5-8,12-13H2,1-4H3,(H2,26,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLECTUAL PROPERTY GmbH US Patent					Assay Description For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...				US Patent US9206184 (2015) BindingDB Entry DOI: 10.7270/Q2SN07SH
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM194899 (US9206184, 80) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCNC(=O)C2)c(Cl)n2ncnc(N)c12 Show InChI InChI=1S/C21H21ClN6O2S/c1-11-5-12-7-15(31-19(12)14(6-11)30-2)17-13(8-27-4-3-24-16(29)9-27)20(22)28-18(17)21(23)25-10-26-28/h5-7,10H,3-4,8-9H2,1-2H3,(H,24,29)(H2,23,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLECTUAL PROPERTY GmbH US Patent					Assay Description For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...				US Patent US9206184 (2015) BindingDB Entry DOI: 10.7270/Q2SN07SH
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302356 ((2S)-1-{[4-Amino-5-(7-methoxy-5-methyl-1-benzothio...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(COC[C@H](C)O)cn2ncnc(N)c12 |r| Show InChI InChI=1S/C20H22N4O3S/c1-11-4-13-6-16(28-19(13)15(5-11)26-3)17-14(9-27-8-12(2)25)7-24-18(17)20(21)22-10-23-24/h4-7,10,12,25H,8-9H2,1-3H3,(H2,21,22,23)/t12-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302372 (US9598416, Example 18 | rac-1-{[4-Amino-5-(7-metho...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCC(O)C2)cn2ncnc(N)c12 Show InChI InChI=1S/C21H23N5O2S/c1-12-5-13-7-17(29-20(13)16(6-12)28-2)18-14(8-25-4-3-15(27)10-25)9-26-19(18)21(22)23-11-24-26/h5-7,9,11,15,27H,3-4,8,10H2,1-2H3,(H2,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM194833 (US9206184, 14) Show SMILES COCc1c(CN2CC[C@](C)(N)C2)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1 |r| Show InChI InChI=1S/C24H30N6O2S/c1-14-7-15-9-19(33-22(15)18(8-14)32-4)20-16(11-31-3)17(10-29-6-5-24(2,26)12-29)30-21(20)23(25)27-13-28-30/h7-9,13H,5-6,10-12,26H2,1-4H3,(H2,25,27,28)/t24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLECTUAL PROPERTY GmbH US Patent					Assay Description For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...				US Patent US9206184 (2015) BindingDB Entry DOI: 10.7270/Q2SN07SH
					More data for this Ligand-Target Pair

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