Compile Data Set for Download or QSAR

Found 980 hits with Last Name = 'hassig' and Initial = 'ca'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50363262 (CHEMBL1944717) Show SMILES Fc1ccc2c(CN(c3cccc(Cl)c3)c3cnccn3)cc(=O)[nH]c2c1F Show InChI InChI=1S/C20H13ClF2N4O/c21-13-2-1-3-14(9-13)27(17-10-24-6-7-25-17)11-12-8-18(28)26-20-15(12)4-5-16(22)19(20)23/h1-10H,11H2,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Afraxis Curated by ChEMBL					Assay Description Inhibition of human iNOS expressed in HEK293 cells assessed as NO production by 2,3-diaminonapthalene-based fluorescence assay				Bioorg Med Chem Lett 22: 1237-41 (2012) Article DOI: 10.1016/j.bmcl.2011.11.073 BindingDB Entry DOI: 10.7270/Q26W9BJ5
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Mus musculus (mouse))	BDBM50363262 (CHEMBL1944717) Show SMILES Fc1ccc2c(CN(c3cccc(Cl)c3)c3cnccn3)cc(=O)[nH]c2c1F Show InChI InChI=1S/C20H13ClF2N4O/c21-13-2-1-3-14(9-13)27(17-10-24-6-7-25-17)11-12-8-18(28)26-20-15(12)4-5-16(22)19(20)23/h1-10H,11H2,(H,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Afraxis Curated by ChEMBL					Assay Description Inhibition of mouse iNOS				Bioorg Med Chem Lett 22: 1237-41 (2012) Article DOI: 10.1016/j.bmcl.2011.11.073 BindingDB Entry DOI: 10.7270/Q26W9BJ5
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50356505 (CHEMBL1911882) Show SMILES CN(CCCNCc1ccc2OCOc2c1)c1nc(ns1)-n1ccnc1 Show InChI InChI=1S/C17H20N6O2S/c1-22(17-20-16(21-26-17)23-8-6-19-11-23)7-2-5-18-10-13-3-4-14-15(9-13)25-12-24-14/h3-4,6,8-9,11,18H,2,5,7,10,12H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Kalypsys Inc. Curated by ChEMBL					Assay Description Inhibition of human iNOS				Bioorg Med Chem Lett 21: 6888-94 (2011) Article DOI: 10.1016/j.bmcl.2011.08.112 BindingDB Entry DOI: 10.7270/Q2XK8FXC
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50356504 (CHEMBL1911883) Show SMILES CN(CCCNCc1ccc2OCOc2c1)c1cc(C)nc(n1)-n1ccnc1 Show InChI InChI=1S/C20H24N6O2/c1-15-10-19(24-20(23-15)26-9-7-22-13-26)25(2)8-3-6-21-12-16-4-5-17-18(11-16)28-14-27-17/h4-5,7,9-11,13,21H,3,6,8,12,14H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Kalypsys Inc. Curated by ChEMBL					Assay Description Inhibition of human iNOS				Bioorg Med Chem Lett 21: 6888-94 (2011) Article DOI: 10.1016/j.bmcl.2011.08.112 BindingDB Entry DOI: 10.7270/Q2XK8FXC
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50363270 (CHEMBL1944884) Show SMILES Cc1ccccc1CN(Cc1cc(=O)[nH]c2c(F)c(F)ccc12)c1cnccn1 Show InChI InChI=1S/C22H18F2N4O/c1-14-4-2-3-5-15(14)12-28(19-11-25-8-9-26-19)13-16-10-20(29)27-22-17(16)6-7-18(23)21(22)24/h2-11H,12-13H2,1H3,(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Afraxis Curated by ChEMBL					Assay Description Inhibition of human iNOS expressed in HEK293 cells assessed as NO production by 2,3-diaminonapthalene-based fluorescence assay				Bioorg Med Chem Lett 22: 1237-41 (2012) Article DOI: 10.1016/j.bmcl.2011.11.073 BindingDB Entry DOI: 10.7270/Q26W9BJ5
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50363277 (CHEMBL1945066) Show SMILES Cn1ncc2c(ncnc12)N(Cc1cc(=O)[nH]c2c(F)c(F)ccc12)c1cccc(Cl)c1 Show InChI InChI=1S/C22H15ClF2N6O/c1-30-21-16(9-28-30)22(27-11-26-21)31(14-4-2-3-13(23)8-14)10-12-7-18(32)29-20-15(12)5-6-17(24)19(20)25/h2-9,11H,10H2,1H3,(H,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Afraxis Curated by ChEMBL					Assay Description Inhibition of human iNOS expressed in HEK293 cells assessed as NO production by 2,3-diaminonapthalene-based fluorescence assay				Bioorg Med Chem Lett 22: 1237-41 (2012) Article DOI: 10.1016/j.bmcl.2011.11.073 BindingDB Entry DOI: 10.7270/Q26W9BJ5
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM29241 (quinolinone, 12) Show SMILES Cc1ncsc1C(=O)N(Cc1cc(=O)[nH]c2c(F)cccc12)c1cccc(Cl)c1 Show InChI InChI=1S/C21H15ClFN3O2S/c1-12-20(29-11-24-12)21(28)26(15-5-2-4-14(22)9-15)10-13-8-18(27)25-19-16(13)6-3-7-17(19)23/h2-9,11H,10H2,1H3,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Kalypsys, Inc Curated by ChEMBL					Assay Description Inhibition of human iNOS				J Med Chem 53: 7739-55 (2010) Article DOI: 10.1021/jm100828n BindingDB Entry DOI: 10.7270/Q29Z9584
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50363269 (CHEMBL1944724) Show SMILES Fc1ccccc1CN(Cc1cc(=O)[nH]c2c(F)c(F)ccc12)c1cnccn1 Show InChI InChI=1S/C21H15F3N4O/c22-16-4-2-1-3-13(16)11-28(18-10-25-7-8-26-18)12-14-9-19(29)27-21-15(14)5-6-17(23)20(21)24/h1-10H,11-12H2,(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Afraxis Curated by ChEMBL					Assay Description Inhibition of human iNOS expressed in HEK293 cells assessed as NO production by 2,3-diaminonapthalene-based fluorescence assay				Bioorg Med Chem Lett 22: 1237-41 (2012) Article DOI: 10.1016/j.bmcl.2011.11.073 BindingDB Entry DOI: 10.7270/Q26W9BJ5
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50363266 (CHEMBL1944721) Show SMILES Fc1ccc2c(CN(Cc3ccccc3Cl)c3cnccn3)cc(=O)[nH]c2c1F Show InChI InChI=1S/C21H15ClF2N4O/c22-16-4-2-1-3-13(16)11-28(18-10-25-7-8-26-18)12-14-9-19(29)27-21-15(14)5-6-17(23)20(21)24/h1-10H,11-12H2,(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Afraxis Curated by ChEMBL					Assay Description Inhibition of human iNOS expressed in HEK293 cells assessed as NO production by 2,3-diaminonapthalene-based fluorescence assay				Bioorg Med Chem Lett 22: 1237-41 (2012) Article DOI: 10.1016/j.bmcl.2011.11.073 BindingDB Entry DOI: 10.7270/Q26W9BJ5
					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Homo sapiens (Human))	BDBM50363262 (CHEMBL1944717) Show SMILES Fc1ccc2c(CN(c3cccc(Cl)c3)c3cnccn3)cc(=O)[nH]c2c1F Show InChI InChI=1S/C20H13ClF2N4O/c21-13-2-1-3-14(9-13)27(17-10-24-6-7-25-17)11-12-8-18(28)26-20-15(12)4-5-16(22)19(20)23/h1-10H,11H2,(H,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Afraxis Curated by ChEMBL					Assay Description Inhibition of human nNOS expressed in HEK293 cells assessed as NO production by 2,3-diaminonapthalene-based fluorescence assay				Bioorg Med Chem Lett 22: 1237-41 (2012) Article DOI: 10.1016/j.bmcl.2011.11.073 BindingDB Entry DOI: 10.7270/Q26W9BJ5
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50363263 (CHEMBL1944718) Show SMILES Fc1ccc2c(CN(c3cccc(Cl)c3)c3ncccn3)cc(=O)[nH]c2c1F Show InChI InChI=1S/C20H13ClF2N4O/c21-13-3-1-4-14(10-13)27(20-24-7-2-8-25-20)11-12-9-17(28)26-19-15(12)5-6-16(22)18(19)23/h1-10H,11H2,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Afraxis Curated by ChEMBL					Assay Description Inhibition of human iNOS expressed in HEK293 cells assessed as NO production by 2,3-diaminonapthalene-based fluorescence assay				Bioorg Med Chem Lett 22: 1237-41 (2012) Article DOI: 10.1016/j.bmcl.2011.11.073 BindingDB Entry DOI: 10.7270/Q26W9BJ5
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50363265 (CHEMBL1944720) Show SMILES Fc1ccc2c(CN(Cc3ccccc3)c3cnccn3)cc(=O)[nH]c2c1F Show InChI InChI=1S/C21H16F2N4O/c22-17-7-6-16-15(10-19(28)26-21(16)20(17)23)13-27(18-11-24-8-9-25-18)12-14-4-2-1-3-5-14/h1-11H,12-13H2,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Afraxis Curated by ChEMBL					Assay Description Inhibition of human iNOS expressed in HEK293 cells assessed as NO production by 2,3-diaminonapthalene-based fluorescence assay				Bioorg Med Chem Lett 22: 1237-41 (2012) Article DOI: 10.1016/j.bmcl.2011.11.073 BindingDB Entry DOI: 10.7270/Q26W9BJ5
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50363261 (CHEMBL1944716) Show SMILES Fc1ccc2c(CN(c3cccc(Cl)c3)c3ccncn3)cc(=O)[nH]c2c1F Show InChI InChI=1S/C20H13ClF2N4O/c21-13-2-1-3-14(9-13)27(17-6-7-24-11-25-17)10-12-8-18(28)26-20-15(12)4-5-16(22)19(20)23/h1-9,11H,10H2,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Afraxis Curated by ChEMBL					Assay Description Inhibition of human iNOS expressed in HEK293 cells assessed as NO production by 2,3-diaminonapthalene-based fluorescence assay				Bioorg Med Chem Lett 22: 1237-41 (2012) Article DOI: 10.1016/j.bmcl.2011.11.073 BindingDB Entry DOI: 10.7270/Q26W9BJ5
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50363281 (CHEMBL1945068) Show SMILES [O-][n+]1cc(CN(c2cccc(Cl)c2)c2ncccn2)c2ccc(F)c(F)c2c1 Show InChI InChI=1S/C20H13ClF2N4O/c21-14-3-1-4-15(9-14)27(20-24-7-2-8-25-20)11-13-10-26(28)12-17-16(13)5-6-18(22)19(17)23/h1-10,12H,11H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Afraxis Curated by ChEMBL					Assay Description Inhibition of human iNOS expressed in HEK293 cells assessed as NO production by 2,3-diaminonapthalene-based fluorescence assay				Bioorg Med Chem Lett 22: 1237-41 (2012) Article DOI: 10.1016/j.bmcl.2011.11.073 BindingDB Entry DOI: 10.7270/Q26W9BJ5
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50363279 (CHEMBL1944890) Show SMILES CN(C)c1cc(ncn1)N(Cc1cc(=O)[nH]c2c(F)c(F)ccc12)c1cccc(Cl)c1 Show InChI InChI=1S/C22H18ClF2N5O/c1-29(2)18-10-19(27-12-26-18)30(15-5-3-4-14(23)9-15)11-13-8-20(31)28-22-16(13)6-7-17(24)21(22)25/h3-10,12H,11H2,1-2H3,(H,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Afraxis Curated by ChEMBL					Assay Description Inhibition of human iNOS expressed in HEK293 cells assessed as NO production by 2,3-diaminonapthalene-based fluorescence assay				Bioorg Med Chem Lett 22: 1237-41 (2012) Article DOI: 10.1016/j.bmcl.2011.11.073 BindingDB Entry DOI: 10.7270/Q26W9BJ5
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50363258 (CHEMBL1944712) Show SMILES Fc1ccc2c(CN(c3cccc(Cl)c3)c3ccccn3)cc(=O)[nH]c2c1F Show InChI InChI=1S/C21H14ClF2N3O/c22-14-4-3-5-15(11-14)27(18-6-1-2-9-25-18)12-13-10-19(28)26-21-16(13)7-8-17(23)20(21)24/h1-11H,12H2,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Afraxis Curated by ChEMBL					Assay Description Inhibition of human iNOS expressed in HEK293 cells assessed as NO production by 2,3-diaminonapthalene-based fluorescence assay				Bioorg Med Chem Lett 22: 1237-41 (2012) Article DOI: 10.1016/j.bmcl.2011.11.073 BindingDB Entry DOI: 10.7270/Q26W9BJ5
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50363272 (CHEMBL1944886) Show SMILES Cc1nccc(n1)N(Cc1cc(=O)[nH]c2c(F)c(F)ccc12)c1cccc(Cl)c1 Show InChI InChI=1S/C21H15ClF2N4O/c1-12-25-8-7-18(26-12)28(15-4-2-3-14(22)10-15)11-13-9-19(29)27-21-16(13)5-6-17(23)20(21)24/h2-10H,11H2,1H3,(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Afraxis Curated by ChEMBL					Assay Description Inhibition of human iNOS expressed in HEK293 cells assessed as NO production by 2,3-diaminonapthalene-based fluorescence assay				Bioorg Med Chem Lett 22: 1237-41 (2012) Article DOI: 10.1016/j.bmcl.2011.11.073 BindingDB Entry DOI: 10.7270/Q26W9BJ5
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50363260 (CHEMBL1944715) Show SMILES Fc1ccc2c(CN(c3cccc(Cl)c3)c3cccnn3)cc(=O)[nH]c2c1F Show InChI InChI=1S/C20H13ClF2N4O/c21-13-3-1-4-14(10-13)27(17-5-2-8-24-26-17)11-12-9-18(28)25-20-15(12)6-7-16(22)19(20)23/h1-10H,11H2,(H,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Afraxis Curated by ChEMBL					Assay Description Inhibition of human iNOS expressed in HEK293 cells assessed as NO production by 2,3-diaminonapthalene-based fluorescence assay				Bioorg Med Chem Lett 22: 1237-41 (2012) Article DOI: 10.1016/j.bmcl.2011.11.073 BindingDB Entry DOI: 10.7270/Q26W9BJ5
					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Homo sapiens (Human))	BDBM50363270 (CHEMBL1944884) Show SMILES Cc1ccccc1CN(Cc1cc(=O)[nH]c2c(F)c(F)ccc12)c1cnccn1 Show InChI InChI=1S/C22H18F2N4O/c1-14-4-2-3-5-15(14)12-28(19-11-25-8-9-26-19)13-16-10-20(29)27-22-17(16)6-7-18(23)21(22)24/h2-11H,12-13H2,1H3,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Afraxis Curated by ChEMBL					Assay Description Inhibition of human nNOS expressed in HEK293 cells assessed as NO production by 2,3-diaminonapthalene-based fluorescence assay				Bioorg Med Chem Lett 22: 1237-41 (2012) Article DOI: 10.1016/j.bmcl.2011.11.073 BindingDB Entry DOI: 10.7270/Q26W9BJ5
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM381415 (4-Chloro-1-(5-methoxy-pyridin-2- ylmethyl)-3-methy...) Show SMILES COc1ccc(Cn2nc(C)c3c(Cl)c(cnc23)C(=O)Nc2ccc(cc2)C(F)(F)F)nc1 Show InChI InChI=1S/C22H17ClF3N5O2/c1-12-18-19(23)17(21(32)29-14-5-3-13(4-6-14)22(24,25)26)10-28-20(18)31(30-12)11-15-7-8-16(33-2)9-27-15/h3-10H,11H2,1-2H3,(H,29,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q29P33Z7
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM381435 (4-Chloro-3-methyl-1-(5-methyl- thiazol-2-ylmethyl)...) Show SMILES Cc1cnc(Cn2nc(C)c3c(Cl)c(cnc23)C(=O)Nc2ccc(Cl)cc2)s1 Show InChI InChI=1S/C19H15Cl2N5OS/c1-10-7-22-15(28-10)9-26-18-16(11(2)25-26)17(21)14(8-23-18)19(27)24-13-5-3-12(20)4-6-13/h3-8H,9H2,1-2H3,(H,24,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q29P33Z7
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM381436 (4-Chloro-3-methyl-1-(5-methyl- thiazol-2-ylmethyl)...) Show SMILES Cc1cnc(Cn2nc(C)c3c(Cl)c(cnc23)C(=O)Nc2ccc(cc2)C(F)(F)F)s1 Show InChI InChI=1S/C20H15ClF3N5OS/c1-10-7-25-15(31-10)9-29-18-16(11(2)28-29)17(21)14(8-26-18)19(30)27-13-5-3-12(4-6-13)20(22,23)24/h3-8H,9H2,1-2H3,(H,27,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q29P33Z7
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM381439 (4-chloro-N-(4-chlorophenyl)-1-((1- ethyl-1H-imidaz...) Show SMILES CCn1ccnc1Cn1nc(C)c2c(Cl)c(cnc12)C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C20H18Cl2N6O/c1-3-27-9-8-23-16(27)11-28-19-17(12(2)26-28)18(22)15(10-24-19)20(29)25-14-6-4-13(21)5-7-14/h4-10H,3,11H2,1-2H3,(H,25,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q29P33Z7
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM381440 (4-chloro-1-((1-ethyl-1H-imidazol- 2-yl)methyl)-3-m...) Show SMILES CCn1ccnc1Cn1nc(C)c2c(Cl)c(cnc12)C(=O)Nc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C21H18ClF3N6O/c1-3-30-9-8-26-16(30)11-31-19-17(12(2)29-31)18(22)15(10-27-19)20(32)28-14-6-4-13(5-7-14)21(23,24)25/h4-10H,3,11H2,1-2H3,(H,28,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q29P33Z7
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM381442 (4-chloro-1-((1-isopropyl-1H- imidazol-2-yl)methyl)...) Show SMILES CC(C)n1ccnc1Cn1nc(C)c2c(Cl)c(cnc12)C(=O)Nc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C22H20ClF3N6O/c1-12(2)31-9-8-27-17(31)11-32-20-18(13(3)30-32)19(23)16(10-28-20)21(33)29-15-6-4-14(5-7-15)22(24,25)26/h4-10,12H,11H2,1-3H3,(H,29,33)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q29P33Z7
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM381447 (4-chloro-1-(pyridin-4-ylmethyl)-N-(4-(trifluoromet...) Show SMILES FC(F)(F)c1ccc(NC(=O)c2cnc3n(Cc4ccncc4)ncc3c2Cl)cc1 Show InChI InChI=1S/C20H13ClF3N5O/c21-17-15-10-27-29(11-12-5-7-25-8-6-12)18(15)26-9-16(17)19(30)28-14-3-1-13(2-4-14)20(22,23)24/h1-10H,11H2,(H,28,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q29P33Z7
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM381448 (4-chloro-N-(4-isopropylphenyl)-1-(pyridin-4-ylmeth...) Show SMILES CC(C)c1ccc(NC(=O)c2cnc3n(Cc4ccncc4)ncc3c2Cl)cc1 Show InChI InChI=1S/C22H20ClN5O/c1-14(2)16-3-5-17(6-4-16)27-22(29)19-11-25-21-18(20(19)23)12-26-28(21)13-15-7-9-24-10-8-15/h3-12,14H,13H2,1-2H3,(H,27,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q29P33Z7
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM381450 (4-chloro-1-(pyridin-3-ylmethyl)-N-(4-(trifluoromet...) Show SMILES FC(F)(F)c1ccc(NC(=O)c2cnc3n(Cc4cccnc4)ncc3c2Cl)cc1 Show InChI InChI=1S/C20H13ClF3N5O/c21-17-15-10-27-29(11-12-2-1-7-25-8-12)18(15)26-9-16(17)19(30)28-14-5-3-13(4-6-14)20(22,23)24/h1-10H,11H2,(H,28,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q29P33Z7
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM381451 (4-chloro-N-(4-isopropylphenyl)-1-(pyridin-3-ylmeth...) Show SMILES CC(C)c1ccc(NC(=O)c2cnc3n(Cc4cccnc4)ncc3c2Cl)cc1 Show InChI InChI=1S/C22H20ClN5O/c1-14(2)16-5-7-17(8-6-16)27-22(29)19-11-25-21-18(20(19)23)12-26-28(21)13-15-4-3-9-24-10-15/h3-12,14H,13H2,1-2H3,(H,27,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q29P33Z7
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM381453 (4-chloro-1-(pyridin-2-ylmethyl)-N-(4-(trifluoromet...) Show SMILES FC(F)(F)c1ccc(NC(=O)c2cnc3n(Cc4ccccn4)ncc3c2Cl)cc1 Show InChI InChI=1S/C20H13ClF3N5O/c21-17-15-10-27-29(11-14-3-1-2-8-25-14)18(15)26-9-16(17)19(30)28-13-6-4-12(5-7-13)20(22,23)24/h1-10H,11H2,(H,28,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q29P33Z7
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM381454 (4-chloro-N-(4-isopropylphenyl)-1-(pyridin-2-ylmeth...) Show SMILES CC(C)c1ccc(NC(=O)c2cnc3n(Cc4ccccn4)ncc3c2Cl)cc1 Show InChI InChI=1S/C22H20ClN5O/c1-14(2)15-6-8-16(9-7-15)27-22(29)19-11-25-21-18(20(19)23)12-26-28(21)13-17-5-3-4-10-24-17/h3-12,14H,13H2,1-2H3,(H,27,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q29P33Z7
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM381464 (4-chloro-N-(4-isopropylphenyl)-1- ((1-methyl-1H-im...) Show SMILES CC(C)c1ccc(NC(=O)c2cnc3n(Cc4cncn4C)ncc3c2Cl)cc1 Show InChI InChI=1S/C21H21ClN6O/c1-13(2)14-4-6-15(7-5-14)26-21(29)18-9-24-20-17(19(18)22)10-25-28(20)11-16-8-23-12-27(16)3/h4-10,12-13H,11H2,1-3H3,(H,26,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q29P33Z7
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM381467 (4-chloro-1-((1-methyl-1H- imidazol-2-yl)methyl)-N-...) Show SMILES Cn1ccnc1Cn1ncc2c(Cl)c(cnc12)C(=O)Nc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C19H14ClF3N6O/c1-28-7-6-24-15(28)10-29-17-13(9-26-29)16(20)14(8-25-17)18(30)27-12-4-2-11(3-5-12)19(21,22)23/h2-9H,10H2,1H3,(H,27,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q29P33Z7
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM381468 (4-chloro-N-(4-isopropylphenyl)-1- ((1-methyl-1H-im...) Show SMILES CC(C)c1ccc(NC(=O)c2cnc3n(Cc4nccn4C)ncc3c2Cl)cc1 Show InChI InChI=1S/C21H21ClN6O/c1-13(2)14-4-6-15(7-5-14)26-21(29)17-10-24-20-16(19(17)22)11-25-28(20)12-18-23-8-9-27(18)3/h4-11,13H,12H2,1-3H3,(H,26,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q29P33Z7
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM381507 (4-Chloro-1-cyclopropyl-3-methyl- 1H-pyrazolo[3,4-b...) Show SMILES Cc1nn(C2CC2)c2ncc(C(=O)Nc3ccc(cc3)C(F)(F)F)c(Cl)c12 Show InChI InChI=1S/C18H14ClF3N4O/c1-9-14-15(19)13(8-23-16(14)26(25-9)12-6-7-12)17(27)24-11-4-2-10(3-5-11)18(20,21)22/h2-5,8,12H,6-7H2,1H3,(H,24,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q29P33Z7
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM381508 (4-Chloro-1-cyclopropyl-3-methyl- 1H-pyrazolo[3,4-b...) Show SMILES CC(C)c1ccc(NC(=O)c2cnc3n(nc(C)c3c2Cl)C2CC2)cc1 Show InChI InChI=1S/C20H21ClN4O/c1-11(2)13-4-6-14(7-5-13)23-20(26)16-10-22-19-17(18(16)21)12(3)24-25(19)15-8-9-15/h4-7,10-11,15H,8-9H2,1-3H3,(H,23,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q29P33Z7
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM381510 (4-Chloro-3-methyl-1-(2-morpholin- 4-yl-ethyl)-1H-p...) Show SMILES Cc1nn(CCN2CCOCC2)c2ncc(C(=O)Nc3ccc(cc3)C(F)(F)F)c(Cl)c12 Show InChI InChI=1S/C21H21ClF3N5O2/c1-13-17-18(22)16(20(31)27-15-4-2-14(3-5-15)21(23,24)25)12-26-19(17)30(28-13)7-6-29-8-10-32-11-9-29/h2-5,12H,6-11H2,1H3,(H,27,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q29P33Z7
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM381511 (4-Chloro-3-methyl-1-(2-morpholin- 4-yl-ethyl)-1H-p...) Show SMILES CC(C)c1ccc(NC(=O)c2cnc3n(CCN4CCOCC4)nc(C)c3c2Cl)cc1 Show InChI InChI=1S/C23H28ClN5O2/c1-15(2)17-4-6-18(7-5-17)26-23(30)19-14-25-22-20(21(19)24)16(3)27-29(22)9-8-28-10-12-31-13-11-28/h4-7,14-15H,8-13H2,1-3H3,(H,26,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q29P33Z7
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM381519 (4-Chloro-3-methyl-1-pyrimidin-4- ylmethyl-1H-pyraz...) Show SMILES Cc1nn(Cc2ccncn2)c2ncc(C(=O)Nc3ccc(cc3)C(F)(F)F)c(Cl)c12 Show InChI InChI=1S/C20H14ClF3N6O/c1-11-16-17(21)15(19(31)28-13-4-2-12(3-5-13)20(22,23)24)8-26-18(16)30(29-11)9-14-6-7-25-10-27-14/h2-8,10H,9H2,1H3,(H,28,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q29P33Z7
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM381527 (4-Chloro-3-methyl-1-(6-methyl- pyrimidin-4-ylmethy...) Show SMILES CC(C)c1ccc(NC(=O)c2cnc3n(Cc4cc(C)ncn4)nc(C)c3c2Cl)cc1 Show InChI InChI=1S/C23H23ClN6O/c1-13(2)16-5-7-17(8-6-16)28-23(31)19-10-25-22-20(21(19)24)15(4)29-30(22)11-18-9-14(3)26-12-27-18/h5-10,12-13H,11H2,1-4H3,(H,28,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q29P33Z7
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM381528 (4-Chloro-3-methyl-1-(6-methyl- pyrimidin-4-ylmethy...) Show SMILES COc1ccc(NC(=O)c2cnc3n(Cc4cc(C)ncn4)nc(C)c3c2Cl)cc1 Show InChI InChI=1S/C21H19ClN6O2/c1-12-8-15(25-11-24-12)10-28-20-18(13(2)27-28)19(22)17(9-23-20)21(29)26-14-4-6-16(30-3)7-5-14/h4-9,11H,10H2,1-3H3,(H,26,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q29P33Z7
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM381530 (4-Chloro-1-(3,4-dimethoxy- pyridin-2-ylmethyl)-3-m...) Show SMILES COc1ccnc(Cn2nc(C)c3c(Cl)c(cnc23)C(=O)Nc2ccc(cc2)C(F)(F)F)c1OC Show InChI InChI=1S/C23H19ClF3N5O3/c1-12-18-19(24)15(22(33)30-14-6-4-13(5-7-14)23(25,26)27)10-29-21(18)32(31-12)11-16-20(35-3)17(34-2)8-9-28-16/h4-10H,11H2,1-3H3,(H,30,33)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q29P33Z7
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM381532 (4-Chloro-1-(6-methoxy-pyrimidin- 4-ylmethyl)-3-met...) Show SMILES COc1cc(Cn2nc(C)c3c(Cl)c(cnc23)C(=O)Nc2ccc(cc2)C(F)(F)F)ncn1 Show InChI InChI=1S/C21H16ClF3N6O2/c1-11-17-18(22)15(20(32)29-13-5-3-12(4-6-13)21(23,24)25)8-26-19(17)31(30-11)9-14-7-16(33-2)28-10-27-14/h3-8,10H,9H2,1-2H3,(H,29,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q29P33Z7
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM381536 (4-Chloro-3-methyl-1-oxazol-2- ylmethyl-1H-pyrazolo...) Show SMILES Cc1nn(Cc2ncco2)c2ncc(C(=O)Nc3ccc(cc3)C(F)(F)F)c(Cl)c12 Show InChI InChI=1S/C19H13ClF3N5O2/c1-10-15-16(20)13(8-25-17(15)28(27-10)9-14-24-6-7-30-14)18(29)26-12-4-2-11(3-5-12)19(21,22)23/h2-8H,9H2,1H3,(H,26,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q29P33Z7
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM381537 (4-Chloro-3-methyl-1-oxazol-2- ylmethyl-1H-pyrazolo...) Show SMILES Cc1nn(Cc2ncco2)c2ncc(C(=O)Nc3ccc(Cl)cc3)c(Cl)c12 Show InChI InChI=1S/C18H13Cl2N5O2/c1-10-15-16(20)13(18(26)23-12-4-2-11(19)3-5-12)8-22-17(15)25(24-10)9-14-21-6-7-27-14/h2-8H,9H2,1H3,(H,23,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q29P33Z7
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM381250 (4-Chloro-1,3-dimethyl-1H- pyrazolo[3,4-b]pyridine-...) Show SMILES Cc1nn(C)c2ncc(C(=O)Nc3cccc(Cl)c3)c(Cl)c12 Show InChI InChI=1S/C15H12Cl2N4O/c1-8-12-13(17)11(7-18-14(12)21(2)20-8)15(22)19-10-5-3-4-9(16)6-10/h3-7H,1-2H3,(H,19,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q29P33Z7
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM381252 (4-Chloro-1,3-dimethyl-1H- pyrazolo[3,4-b]pyridine-...) Show SMILES Cc1nn(C)c2ncc(C(=O)Nc3ccc(cc3)C(F)(F)F)c(Cl)c12 Show InChI InChI=1S/C16H12ClF3N4O/c1-8-12-13(17)11(7-21-14(12)24(2)23-8)15(25)22-10-5-3-9(4-6-10)16(18,19)20/h3-7H,1-2H3,(H,22,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q29P33Z7
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM381253 (4-Chloro-1,3-dimethyl-1H- pyrazolo[3,4-b]pyridine-...) Show SMILES Cc1nn(C)c2ncc(C(=O)Nc3cccc(c3)C(F)(F)F)c(Cl)c12 Show InChI InChI=1S/C16H12ClF3N4O/c1-8-12-13(17)11(7-21-14(12)24(2)23-8)15(25)22-10-5-3-4-9(6-10)16(18,19)20/h3-7H,1-2H3,(H,22,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q29P33Z7
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM381255 (4-Chloro-1,3-dimethyl-1H- pyrazolo[3,4-b]pyridine-...) Show SMILES CC(C)c1ccc(NC(=O)c2cnc3n(C)nc(C)c3c2Cl)cc1 Show InChI InChI=1S/C18H19ClN4O/c1-10(2)12-5-7-13(8-6-12)21-18(24)14-9-20-17-15(16(14)19)11(3)22-23(17)4/h5-10H,1-4H3,(H,21,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q29P33Z7
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM381256 (4-Chloro-1,3-dimethyl-1H- pyrazolo[3,4-b]pyridine-...) Show SMILES CC(C)c1cccc(NC(=O)c2cnc3n(C)nc(C)c3c2Cl)c1 Show InChI InChI=1S/C18H19ClN4O/c1-10(2)12-6-5-7-13(8-12)21-18(24)14-9-20-17-15(16(14)19)11(3)22-23(17)4/h5-10H,1-4H3,(H,21,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q29P33Z7
					More data for this Ligand-Target Pair

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