Compile Data Set for Download or QSAR

Found 281 hits with Last Name = 'jaleel' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine protease hepsin (Homo sapiens (Human))	BDBM50130870 (CHEMBL3632759) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cccc(n1)C1(O)CCCCC1 Show InChI InChI=1S/C20H22N4O/c21-19(22)13-7-8-15-14(11-13)12-17(23-15)16-5-4-6-18(24-16)20(25)9-2-1-3-10-20/h4-8,11-12,23,25H,1-3,9-10H2,(H3,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	PDB Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human recombinant hepsin by fluorescence based assay using 65 uM BOC-Gln-Arg-Arg -AMC as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair				3D Structure (crystal)
Serine protease hepsin (Homo sapiens (Human))	BDBM50130874 (CHEMBL3632761) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cccc([n+]1[O-])C1(O)CCCCC1 Show InChI InChI=1S/C20H22N4O2/c21-19(22)13-7-8-15-14(11-13)12-16(23-15)17-5-4-6-18(24(17)26)20(25)9-2-1-3-10-20/h4-8,11-12,23,25H,1-3,9-10H2,(H3,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human recombinant hepsin by fluorescence based assay using 65 uM BOC-Gln-Arg-Arg -AMC as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Serine protease hepsin (Homo sapiens (Human))	BDBM50130871 (CHEMBL3632760) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cccc(n1)C1(F)CCCCC1 Show InChI InChI=1S/C20H21FN4/c21-20(9-2-1-3-10-20)18-6-4-5-16(25-18)17-12-14-11-13(19(22)23)7-8-15(14)24-17/h4-8,11-12,24H,1-3,9-10H2,(H3,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human recombinant hepsin by fluorescence based assay using 65 uM BOC-Gln-Arg-Arg -AMC as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Trypsin (Homo sapiens (Human))	BDBM50130870 (CHEMBL3632759) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cccc(n1)C1(O)CCCCC1 Show InChI InChI=1S/C20H22N4O/c21-19(22)13-7-8-15-14(11-13)12-17(23-15)16-5-4-6-18(24-16)20(25)9-2-1-3-10-20/h4-8,11-12,23,25H,1-3,9-10H2,(H3,21,22)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	Article PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human trypsin by fluorescence based assay using 25 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Trypsin (Homo sapiens (Human))	BDBM50130871 (CHEMBL3632760) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cccc(n1)C1(F)CCCCC1 Show InChI InChI=1S/C20H21FN4/c21-20(9-2-1-3-10-20)18-6-4-5-16(25-18)17-12-14-11-13(19(22)23)7-8-15(14)24-17/h4-8,11-12,24H,1-3,9-10H2,(H3,22,23)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human trypsin by fluorescence based assay using 25 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM50130868 (CHEMBL3632757) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cccc(N2CCCCC2)c1O Show InChI InChI=1S/C20H22N4O/c21-20(22)13-7-8-16-14(11-13)12-17(23-16)15-5-4-6-18(19(15)25)24-9-2-1-3-10-24/h4-8,11-12,23,25H,1-3,9-10H2,(H3,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human recombinant matriptase by fluorescence based assay using 20 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Serine protease hepsin (Homo sapiens (Human))	BDBM50130869 (CHEMBL3632758) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cccc(n1)N1CCCCC1 Show InChI InChI=1S/C19H21N5/c20-19(21)13-7-8-15-14(11-13)12-17(22-15)16-5-4-6-18(23-16)24-9-2-1-3-10-24/h4-8,11-12,22H,1-3,9-10H2,(H3,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human recombinant hepsin by fluorescence based assay using 65 uM BOC-Gln-Arg-Arg -AMC as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Coagulation factor X (Bos taurus)	BDBM50130871 (CHEMBL3632760) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cccc(n1)C1(F)CCCCC1 Show InChI InChI=1S/C20H21FN4/c21-20(9-2-1-3-10-20)18-6-4-5-16(25-18)17-12-14-11-13(19(22)23)7-8-15(14)24-17/h4-8,11-12,24H,1-3,9-10H2,(H3,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of bovine factor 10a by fluorescence based assay using CH3OCO-D-CHA-Gly-Arg-pNA.AcoH as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Trypsin (Homo sapiens (Human))	BDBM50130866 (CHEMBL3632755) Show SMILES CC(C)c1cccc(-c2cc3cc(ccc3[nH]2)C(N)=N)c1O Show InChI InChI=1S/C18H19N3O/c1-10(2)13-4-3-5-14(17(13)22)16-9-12-8-11(18(19)20)6-7-15(12)21-16/h3-10,21-22H,1-2H3,(H3,19,20)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human trypsin by fluorescence based assay using 25 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM50130871 (CHEMBL3632760) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cccc(n1)C1(F)CCCCC1 Show InChI InChI=1S/C20H21FN4/c21-20(9-2-1-3-10-20)18-6-4-5-16(25-18)17-12-14-11-13(19(22)23)7-8-15(14)24-17/h4-8,11-12,24H,1-3,9-10H2,(H3,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human recombinant matriptase by fluorescence based assay using 20 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Trypsin (Homo sapiens (Human))	BDBM50130874 (CHEMBL3632761) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cccc([n+]1[O-])C1(O)CCCCC1 Show InChI InChI=1S/C20H22N4O2/c21-19(22)13-7-8-15-14(11-13)12-16(23-15)17-5-4-6-18(24(17)26)20(25)9-2-1-3-10-20/h4-8,11-12,23,25H,1-3,9-10H2,(H3,21,22)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human trypsin by fluorescence based assay using 25 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Coagulation factor X (Bos taurus)	BDBM50130866 (CHEMBL3632755) Show SMILES CC(C)c1cccc(-c2cc3cc(ccc3[nH]2)C(N)=N)c1O Show InChI InChI=1S/C18H19N3O/c1-10(2)13-4-3-5-14(17(13)22)16-9-12-8-11(18(19)20)6-7-15(12)21-16/h3-10,21-22H,1-2H3,(H3,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of bovine factor 10a by fluorescence based assay using CH3OCO-D-CHA-Gly-Arg-pNA.AcoH as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM50130874 (CHEMBL3632761) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cccc([n+]1[O-])C1(O)CCCCC1 Show InChI InChI=1S/C20H22N4O2/c21-19(22)13-7-8-15-14(11-13)12-16(23-15)17-5-4-6-18(24(17)26)20(25)9-2-1-3-10-20/h4-8,11-12,23,25H,1-3,9-10H2,(H3,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human recombinant matriptase by fluorescence based assay using 20 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50130870 (CHEMBL3632759) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cccc(n1)C1(O)CCCCC1 Show InChI InChI=1S/C20H22N4O/c21-19(22)13-7-8-15-14(11-13)12-17(23-15)16-5-4-6-18(24-16)20(25)9-2-1-3-10-20/h4-8,11-12,23,25H,1-3,9-10H2,(H3,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	Article PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human uPA by fluorescence based assay using L-PyroGlu-Gly-Arg-pNA.HCl as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Coagulation factor X (Bos taurus)	BDBM50130870 (CHEMBL3632759) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cccc(n1)C1(O)CCCCC1 Show InChI InChI=1S/C20H22N4O/c21-19(22)13-7-8-15-14(11-13)12-17(23-15)16-5-4-6-18(24-16)20(25)9-2-1-3-10-20/h4-8,11-12,23,25H,1-3,9-10H2,(H3,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	Article PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of bovine factor 10a by fluorescence based assay using CH3OCO-D-CHA-Gly-Arg-pNA.AcoH as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Serine protease hepsin (Homo sapiens (Human))	BDBM50130868 (CHEMBL3632757) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cccc(N2CCCCC2)c1O Show InChI InChI=1S/C20H22N4O/c21-20(22)13-7-8-16-14(11-13)12-17(23-16)15-5-4-6-18(19(15)25)24-9-2-1-3-10-24/h4-8,11-12,23,25H,1-3,9-10H2,(H3,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human recombinant hepsin by fluorescence based assay using 65 uM BOC-Gln-Arg-Arg -AMC as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM50130869 (CHEMBL3632758) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cccc(n1)N1CCCCC1 Show InChI InChI=1S/C19H21N5/c20-19(21)13-7-8-15-14(11-13)12-17(22-15)16-5-4-6-18(23-16)24-9-2-1-3-10-24/h4-8,11-12,22H,1-3,9-10H2,(H3,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human recombinant matriptase by fluorescence based assay using 20 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50130866 (CHEMBL3632755) Show SMILES CC(C)c1cccc(-c2cc3cc(ccc3[nH]2)C(N)=N)c1O Show InChI InChI=1S/C18H19N3O/c1-10(2)13-4-3-5-14(17(13)22)16-9-12-8-11(18(19)20)6-7-15(12)21-16/h3-10,21-22H,1-2H3,(H3,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human thrombin by fluorescence based assay using 100 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM50130870 (CHEMBL3632759) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cccc(n1)C1(O)CCCCC1 Show InChI InChI=1S/C20H22N4O/c21-19(22)13-7-8-15-14(11-13)12-17(23-15)16-5-4-6-18(24-16)20(25)9-2-1-3-10-20/h4-8,11-12,23,25H,1-3,9-10H2,(H3,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human recombinant matriptase by fluorescence based assay using 20 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50130870 (CHEMBL3632759) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cccc(n1)C1(O)CCCCC1 Show InChI InChI=1S/C20H22N4O/c21-19(22)13-7-8-15-14(11-13)12-17(23-15)16-5-4-6-18(24-16)20(25)9-2-1-3-10-20/h4-8,11-12,23,25H,1-3,9-10H2,(H3,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human thrombin by fluorescence based assay using 100 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50130869 (CHEMBL3632758) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cccc(n1)N1CCCCC1 Show InChI InChI=1S/C19H21N5/c20-19(21)13-7-8-15-14(11-13)12-17(22-15)16-5-4-6-18(23-16)24-9-2-1-3-10-24/h4-8,11-12,22H,1-3,9-10H2,(H3,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human uPA by fluorescence based assay using L-PyroGlu-Gly-Arg-pNA.HCl as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50102768 (2-(2-Hydroxy-phenyl)-1H-indole-5-carboxamidine | C...) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1ccccc1O Show InChI InChI=1S/C15H13N3O/c16-15(17)9-5-6-12-10(7-9)8-13(18-12)11-3-1-2-4-14(11)19/h1-8,18-19H,(H3,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human uPA by fluorescence based assay using L-PyroGlu-Gly-Arg-pNA.HCl as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50130871 (CHEMBL3632760) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cccc(n1)C1(F)CCCCC1 Show InChI InChI=1S/C20H21FN4/c21-20(9-2-1-3-10-20)18-6-4-5-16(25-18)17-12-14-11-13(19(22)23)7-8-15(14)24-17/h4-8,11-12,24H,1-3,9-10H2,(H3,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human uPA by fluorescence based assay using L-PyroGlu-Gly-Arg-pNA.HCl as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50102768 (2-(2-Hydroxy-phenyl)-1H-indole-5-carboxamidine | C...) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1ccccc1O Show InChI InChI=1S/C15H13N3O/c16-15(17)9-5-6-12-10(7-9)8-13(18-12)11-3-1-2-4-14(11)19/h1-8,18-19H,(H3,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human factor 10a by fluorescence based assay using CH3OCO-D-CHA-Gly-Arg-pNA.AcoH as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50130871 (CHEMBL3632760) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cccc(n1)C1(F)CCCCC1 Show InChI InChI=1S/C20H21FN4/c21-20(9-2-1-3-10-20)18-6-4-5-16(25-18)17-12-14-11-13(19(22)23)7-8-15(14)24-17/h4-8,11-12,24H,1-3,9-10H2,(H3,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human thrombin by fluorescence based assay using 100 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM50130866 (CHEMBL3632755) Show SMILES CC(C)c1cccc(-c2cc3cc(ccc3[nH]2)C(N)=N)c1O Show InChI InChI=1S/C18H19N3O/c1-10(2)13-4-3-5-14(17(13)22)16-9-12-8-11(18(19)20)6-7-15(12)21-16/h3-10,21-22H,1-2H3,(H3,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human recombinant matriptase by fluorescence based assay using 20 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Serine protease hepsin (Homo sapiens (Human))	BDBM50130867 (CHEMBL3632756) Show SMILES CC(C)c1cc(Cl)cc(-c2cc3cc(ccc3[nH]2)C(N)=N)c1O Show InChI InChI=1S/C18H18ClN3O/c1-9(2)13-7-12(19)8-14(17(13)23)16-6-11-5-10(18(20)21)3-4-15(11)22-16/h3-9,22-23H,1-2H3,(H3,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human recombinant hepsin by fluorescence based assay using 65 uM BOC-Gln-Arg-Arg -AMC as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM50130867 (CHEMBL3632756) Show SMILES CC(C)c1cc(Cl)cc(-c2cc3cc(ccc3[nH]2)C(N)=N)c1O Show InChI InChI=1S/C18H18ClN3O/c1-9(2)13-7-12(19)8-14(17(13)23)16-6-11-5-10(18(20)21)3-4-15(11)22-16/h3-9,22-23H,1-2H3,(H3,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human recombinant matriptase by fluorescence based assay using 20 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Serine protease hepsin (Homo sapiens (Human))	BDBM50130866 (CHEMBL3632755) Show SMILES CC(C)c1cccc(-c2cc3cc(ccc3[nH]2)C(N)=N)c1O Show InChI InChI=1S/C18H19N3O/c1-10(2)13-4-3-5-14(17(13)22)16-9-12-8-11(18(19)20)6-7-15(12)21-16/h3-10,21-22H,1-2H3,(H3,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human recombinant hepsin by fluorescence based assay using 65 uM BOC-Gln-Arg-Arg -AMC as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50100897 (2-(2-Hydroxy-phenyl)-1H-benzoimidazole-5-carboxami...) Show SMILES NC(=N)c1ccc2nc([nH]c2c1)-c1ccccc1O Show InChI InChI=1S/C14H12N4O/c15-13(16)8-5-6-10-11(7-8)18-14(17-10)9-3-1-2-4-12(9)19/h1-7,19H,(H3,15,16)(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human uPA by fluorescence based assay using L-PyroGlu-Gly-Arg-pNA.HCl as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50130874 (CHEMBL3632761) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cccc([n+]1[O-])C1(O)CCCCC1 Show InChI InChI=1S/C20H22N4O2/c21-19(22)13-7-8-15-14(11-13)12-16(23-15)17-5-4-6-18(24(17)26)20(25)9-2-1-3-10-20/h4-8,11-12,23,25H,1-3,9-10H2,(H3,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human uPA by fluorescence based assay using L-PyroGlu-Gly-Arg-pNA.HCl as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Trypsin (Homo sapiens (Human))	BDBM50102768 (2-(2-Hydroxy-phenyl)-1H-indole-5-carboxamidine | C...) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1ccccc1O Show InChI InChI=1S/C15H13N3O/c16-15(17)9-5-6-12-10(7-9)8-13(18-12)11-3-1-2-4-14(11)19/h1-8,18-19H,(H3,16,17)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human trypsin by fluorescence based assay using 25 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Coagulation factor X (Bos taurus)	BDBM50130874 (CHEMBL3632761) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cccc([n+]1[O-])C1(O)CCCCC1 Show InChI InChI=1S/C20H22N4O2/c21-19(22)13-7-8-15-14(11-13)12-16(23-15)17-5-4-6-18(24(17)26)20(25)9-2-1-3-10-20/h4-8,11-12,23,25H,1-3,9-10H2,(H3,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of bovine factor 10a by fluorescence based assay using CH3OCO-D-CHA-Gly-Arg-pNA.AcoH as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50130874 (CHEMBL3632761) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cccc([n+]1[O-])C1(O)CCCCC1 Show InChI InChI=1S/C20H22N4O2/c21-19(22)13-7-8-15-14(11-13)12-16(23-15)17-5-4-6-18(24(17)26)20(25)9-2-1-3-10-20/h4-8,11-12,23,25H,1-3,9-10H2,(H3,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human thrombin by fluorescence based assay using 100 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50102768 (2-(2-Hydroxy-phenyl)-1H-indole-5-carboxamidine | C...) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1ccccc1O Show InChI InChI=1S/C15H13N3O/c16-15(17)9-5-6-12-10(7-9)8-13(18-12)11-3-1-2-4-14(11)19/h1-8,18-19H,(H3,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human plasmin by fluorescence based assay using pyroGlu-Phe-Lys-pNA.HCl as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50102768 (2-(2-Hydroxy-phenyl)-1H-indole-5-carboxamidine | C...) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1ccccc1O Show InChI InChI=1S/C15H13N3O/c16-15(17)9-5-6-12-10(7-9)8-13(18-12)11-3-1-2-4-14(11)19/h1-8,18-19H,(H3,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human thrombin by fluorescence based assay using 100 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Coagulation factor X (Bos taurus)	BDBM50100897 (2-(2-Hydroxy-phenyl)-1H-benzoimidazole-5-carboxami...) Show SMILES NC(=N)c1ccc2nc([nH]c2c1)-c1ccccc1O Show InChI InChI=1S/C14H12N4O/c15-13(16)8-5-6-10-11(7-8)18-14(17-10)9-3-1-2-4-12(9)19/h1-7,19H,(H3,15,16)(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of bovine factor 10a by fluorescence based assay using CH3OCO-D-CHA-Gly-Arg-pNA.AcoH as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Trypsin (Homo sapiens (Human))	BDBM50100897 (2-(2-Hydroxy-phenyl)-1H-benzoimidazole-5-carboxami...) Show SMILES NC(=N)c1ccc2nc([nH]c2c1)-c1ccccc1O Show InChI InChI=1S/C14H12N4O/c15-13(16)8-5-6-10-11(7-8)18-14(17-10)9-3-1-2-4-12(9)19/h1-7,19H,(H3,15,16)(H,17,18)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human trypsin by fluorescence based assay using 25 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Serine protease hepsin (Homo sapiens (Human))	BDBM50102768 (2-(2-Hydroxy-phenyl)-1H-indole-5-carboxamidine | C...) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1ccccc1O Show InChI InChI=1S/C15H13N3O/c16-15(17)9-5-6-12-10(7-9)8-13(18-12)11-3-1-2-4-14(11)19/h1-8,18-19H,(H3,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human recombinant hepsin by fluorescence based assay using 65 uM BOC-Gln-Arg-Arg -AMC as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Serine protease hepsin (Homo sapiens (Human))	BDBM50100897 (2-(2-Hydroxy-phenyl)-1H-benzoimidazole-5-carboxami...) Show SMILES NC(=N)c1ccc2nc([nH]c2c1)-c1ccccc1O Show InChI InChI=1S/C14H12N4O/c15-13(16)8-5-6-10-11(7-8)18-14(17-10)9-3-1-2-4-12(9)19/h1-7,19H,(H3,15,16)(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human recombinant hepsin by fluorescence based assay using 65 uM BOC-Gln-Arg-Arg -AMC as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50100897 (2-(2-Hydroxy-phenyl)-1H-benzoimidazole-5-carboxami...) Show SMILES NC(=N)c1ccc2nc([nH]c2c1)-c1ccccc1O Show InChI InChI=1S/C14H12N4O/c15-13(16)8-5-6-10-11(7-8)18-14(17-10)9-3-1-2-4-12(9)19/h1-7,19H,(H3,15,16)(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human plasmin by fluorescence based assay using pyroGlu-Phe-Lys-pNA.HCl as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50100897 (2-(2-Hydroxy-phenyl)-1H-benzoimidazole-5-carboxami...) Show SMILES NC(=N)c1ccc2nc([nH]c2c1)-c1ccccc1O Show InChI InChI=1S/C14H12N4O/c15-13(16)8-5-6-10-11(7-8)18-14(17-10)9-3-1-2-4-12(9)19/h1-7,19H,(H3,15,16)(H,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human thrombin by fluorescence based assay using 100 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM50102768 (2-(2-Hydroxy-phenyl)-1H-indole-5-carboxamidine | C...) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1ccccc1O Show InChI InChI=1S/C15H13N3O/c16-15(17)9-5-6-12-10(7-9)8-13(18-12)11-3-1-2-4-14(11)19/h1-8,18-19H,(H3,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human recombinant matriptase by fluorescence based assay using 20 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Serine protease hepsin (Homo sapiens (Human))	BDBM50027306 (1H-Indole-5-carboxamidine | CHEMBL26490) Show SMILES NC(=N)c1ccc2[nH]ccc2c1 Show InChI InChI=1S/C9H9N3/c10-9(11)7-1-2-8-6(5-7)3-4-12-8/h1-5,12H,(H3,10,11)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aurigene Discovery Technologies Limited Curated by ChEMBL					Assay Description Inhibition of human recombinant hepsin by fluorescence based assay using 65 uM BOC-Gln-Arg-Arg -AMC as substrate				Bioorg Med Chem Lett 25: 5309-14 (2015) Article DOI: 10.1016/j.bmcl.2015.09.042 BindingDB Entry DOI: 10.7270/Q24B335X
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490051 ((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](Cc2cccs2)NC(=O)c2ccc(F)cc2)cc1 |r| Show InChI InChI=1S/C24H26FN3O4S2/c1-24(2,3)28-34(31,32)20-12-10-18(11-13-20)26-23(30)21(15-19-5-4-14-33-19)27-22(29)16-6-8-17(25)9-7-16/h4-14,21,28H,15H2,1-3H3,(H,26,30)(H,27,29)/t21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of USP30 (unknown origin) using Ubiquitin-Rhodamine110-Glycine as substrate incubated for 15 mins followed by substrate addition and measu...				Citation and Details Article DOI: 10.1016/j.bmcl.2018.05.013 BindingDB Entry DOI: 10.7270/Q2NK3JNN
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490037 ((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](CC2CCCCC2)NC(=O)c2ccc(F)cc2)cc1 |r| Show InChI InChI=1S/C26H34FN3O4S/c1-26(2,3)30-35(33,34)22-15-13-21(14-16-22)28-25(32)23(17-18-7-5-4-6-8-18)29-24(31)19-9-11-20(27)12-10-19/h9-16,18,23,30H,4-8,17H2,1-3H3,(H,28,32)(H,29,31)/t23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of USP30 (unknown origin) using Ubiquitin-Rhodamine110-Glycine as substrate incubated for 15 mins followed by substrate addition and measu...				Citation and Details Article DOI: 10.1016/j.bmcl.2018.05.013 BindingDB Entry DOI: 10.7270/Q2NK3JNN
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490029 ((S)-N-(1-((4-(tert- butyl)sulfamoyl)phenyl)amino)-...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](Cc2ccccc2)NC(=O)c2ccc(F)cc2)cc1 |r| Show InChI InChI=1S/C26H28FN3O4S/c1-26(2,3)30-35(33,34)22-15-13-21(14-16-22)28-25(32)23(17-18-7-5-4-6-8-18)29-24(31)19-9-11-20(27)12-10-19/h4-16,23,30H,17H2,1-3H3,(H,28,32)(H,29,31)/t23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of USP30 (unknown origin) using Ubiquitin-Rhodamine110-Glycine as substrate incubated for 15 mins followed by substrate addition and measu...				Citation and Details Article DOI: 10.1016/j.bmcl.2018.05.013 BindingDB Entry DOI: 10.7270/Q2NK3JNN
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490068 ((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](Cc2ccncc2)NC(=O)c2ccc(F)cc2)cc1 |r| Show InChI InChI=1S/C25H27FN4O4S/c1-25(2,3)30-35(33,34)21-10-8-20(9-11-21)28-24(32)22(16-17-12-14-27-15-13-17)29-23(31)18-4-6-19(26)7-5-18/h4-15,22,30H,16H2,1-3H3,(H,28,32)(H,29,31)/t22-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of USP30 (unknown origin) using Ubiquitin-Rhodamine110-Glycine as substrate incubated for 15 mins followed by substrate addition and measu...				Citation and Details Article DOI: 10.1016/j.bmcl.2018.05.013 BindingDB Entry DOI: 10.7270/Q2NK3JNN
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490042 ((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](CC2CCCCC2)NC(=O)c2ccc(F)c(F)c2)cc1 |r| Show InChI InChI=1S/C26H33F2N3O4S/c1-26(2,3)31-36(34,35)20-12-10-19(11-13-20)29-25(33)23(15-17-7-5-4-6-8-17)30-24(32)18-9-14-21(27)22(28)16-18/h9-14,16-17,23,31H,4-8,15H2,1-3H3,(H,29,33)(H,30,32)/t23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of USP30 (unknown origin) using Ubiquitin-Rhodamine110-Glycine as substrate incubated for 15 mins followed by substrate addition and measu...				Citation and Details Article DOI: 10.1016/j.bmcl.2018.05.013 BindingDB Entry DOI: 10.7270/Q2NK3JNN
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human))	BDBM490045 ((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](Cc2cccs2)NC(=O)C2CCCCC2)cc1 |r| Show InChI InChI=1S/C24H33N3O4S2/c1-24(2,3)27-33(30,31)20-13-11-18(12-14-20)25-23(29)21(16-19-10-7-15-32-19)26-22(28)17-8-5-4-6-9-17/h7,10-15,17,21,27H,4-6,8-9,16H2,1-3H3,(H,25,29)(H,26,28)/t21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of USP30 (unknown origin) using Ubiquitin-Rhodamine110-Glycine as substrate incubated for 15 mins followed by substrate addition and measu...				Citation and Details Article DOI: 10.1016/j.bmcl.2018.05.013 BindingDB Entry DOI: 10.7270/Q2NK3JNN
					More data for this Ligand-Target Pair

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