Compile Data Set for Download or QSAR

Found 88 hits with Last Name = 'kirk' and Initial = 'gw'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50105466 ((S)-6-Amino-2-[(R)-2-[(4-benzenesulfonyl-piperazin...) Show SMILES CC(C)(C)OC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)N1CCN(CC1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C32H44N6O6S/c1-32(2,3)44-30(40)27(15-9-10-16-33)35-29(39)28(21-23-22-34-26-14-8-7-13-25(23)26)36-31(41)37-17-19-38(20-18-37)45(42,43)24-11-5-4-6-12-24/h4-8,11-14,22,27-28,34H,9-10,15-21,33H2,1-3H3,(H,35,39)(H,36,41)/t27-,28+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Inhibitory concentration of the compound towards binding of sst2 receptor using [125I]-somatostatin as radioligand in Neuro2A cells				Bioorg Med Chem Lett 11: 2731-4 (2001) BindingDB Entry DOI: 10.7270/Q2JW8D5S
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50105472 ((S)-6-Amino-2-[(R)-2-[(1-benzenesulfonyl-piperidin...) Show SMILES CC(C)(C)OC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)C1CCN(CC1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C33H45N5O6S/c1-33(2,3)44-32(41)28(15-9-10-18-34)36-31(40)29(21-24-22-35-27-14-8-7-13-26(24)27)37-30(39)23-16-19-38(20-17-23)45(42,43)25-11-5-4-6-12-25/h4-8,11-14,22-23,28-29,35H,9-10,15-21,34H2,1-3H3,(H,36,40)(H,37,39)/t28-,29+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Inhibitory concentration of the compound towards binding of sst2 receptor using [125I]-somatostatin as radioligand in Neuro2A cells				Bioorg Med Chem Lett 11: 2731-4 (2001) BindingDB Entry DOI: 10.7270/Q2JW8D5S
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50105465 ((4R,8S,11S,17S)-8-(4-Amino-butyl)-17-(2-amino-3-na...) Show SMILES CC(C)(C)C1N[C@@H](CSSC[C@@H](NC(=O)C(N)Cc2cccc(F)c2)C(=O)NC(Cc2cccnc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C1=O)C(=O)NC(Cc1cccc2ccccc12)C(N)=O Show InChI InChI=1S/C58H70FN11O7S2/c1-58(2,3)51-50(71)44(22-8-9-23-60)66-55(75)47(29-38-31-64-43-21-7-6-20-41(38)43)69-54(74)46(27-35-14-12-24-63-30-35)68-57(77)49(70-53(73)42(61)26-34-13-10-18-39(59)25-34)33-79-78-32-48(65-51)56(76)67-45(52(62)72)28-37-17-11-16-36-15-4-5-19-40(36)37/h4-7,10-21,24-25,30-31,42,44-49,51,64-65H,8-9,22-23,26-29,32-33,60-61H2,1-3H3,(H2,62,72)(H,66,75)(H,67,76)(H,68,77)(H,69,74)(H,70,73)/t42?,44-,45?,46?,47-,48-,49+,51?/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Inhibitory concentration of the compound towards binding of sst2 receptor using [125I]-somatostatin as radioligand in Neuro2A cells				Bioorg Med Chem Lett 11: 2731-4 (2001) BindingDB Entry DOI: 10.7270/Q2JW8D5S
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50105470 ((S)-6-Amino-2-((R)-3-(1H-indol-3-yl)-2-{[4-(4-meth...) Show SMILES Cc1ccc(cc1)C(=O)N1CCN(CC1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCN)C(=O)OC(C)(C)C Show InChI InChI=1S/C34H46N6O5/c1-23-12-14-24(15-13-23)31(42)39-17-19-40(20-18-39)33(44)38-29(21-25-22-36-27-10-6-5-9-26(25)27)30(41)37-28(11-7-8-16-35)32(43)45-34(2,3)4/h5-6,9-10,12-15,22,28-29,36H,7-8,11,16-21,35H2,1-4H3,(H,37,41)(H,38,44)/t28-,29+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Inhibitory concentration of the compound towards binding of sst2 receptor using [125I]-somatostatin as radioligand in Neuro2A cells				Bioorg Med Chem Lett 11: 2731-4 (2001) BindingDB Entry DOI: 10.7270/Q2JW8D5S
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50105469 ((S)-6-Amino-2-((R)-3-(1H-indol-3-yl)-2-{[4-(2-oxo-...) Show SMILES CC(C)(C)OC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)N1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C34H45N7O5/c1-34(2,3)46-31(43)27(13-8-9-17-35)37-30(42)28(20-22-21-36-25-11-5-4-10-24(22)25)39-32(44)40-18-15-23(16-19-40)41-29-14-7-6-12-26(29)38-33(41)45/h4-7,10-12,14,21,23,27-28,36H,8-9,13,15-20,35H2,1-3H3,(H,37,42)(H,38,45)(H,39,44)/t27-,28+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Antagonistic activity of the compound towards sst2 receptor in GH4C1 cells a concentration of 1-2 x 10e6/mL incubated for 20 minutes				Bioorg Med Chem Lett 11: 2731-4 (2001) BindingDB Entry DOI: 10.7270/Q2JW8D5S
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50105469 ((S)-6-Amino-2-((R)-3-(1H-indol-3-yl)-2-{[4-(2-oxo-...) Show SMILES CC(C)(C)OC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)N1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C34H45N7O5/c1-34(2,3)46-31(43)27(13-8-9-17-35)37-30(42)28(20-22-21-36-25-11-5-4-10-24(22)25)39-32(44)40-18-15-23(16-19-40)41-29-14-7-6-12-26(29)38-33(41)45/h4-7,10-12,14,21,23,27-28,36H,8-9,13,15-20,35H2,1-3H3,(H,37,42)(H,38,45)(H,39,44)/t27-,28+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Antagonistic activity of the compound towards sst2 receptor in GH4C1 cells a concentration of 1-2 x 10e6/mL incubated for 20 minutes				Bioorg Med Chem Lett 11: 2731-4 (2001) BindingDB Entry DOI: 10.7270/Q2JW8D5S
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50105468 ((S)-6-Amino-2-[(R)-2-[(4-benzoyl-piperazine-1-carb...) Show SMILES CC(C)(C)OC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)N1CCN(CC1)C(=O)c1ccccc1 Show InChI InChI=1S/C33H44N6O5/c1-33(2,3)44-31(42)27(15-9-10-16-34)36-29(40)28(21-24-22-35-26-14-8-7-13-25(24)26)37-32(43)39-19-17-38(18-20-39)30(41)23-11-5-4-6-12-23/h4-8,11-14,22,27-28,35H,9-10,15-21,34H2,1-3H3,(H,36,40)(H,37,43)/t27-,28+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.90	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Inhibitory concentration of the compound towards binding of sst2 receptor using [125I]-somatostatin as radioligand in Neuro2A cells				Bioorg Med Chem Lett 11: 2731-4 (2001) BindingDB Entry DOI: 10.7270/Q2JW8D5S
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50105468 ((S)-6-Amino-2-[(R)-2-[(4-benzoyl-piperazine-1-carb...) Show SMILES CC(C)(C)OC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)N1CCN(CC1)C(=O)c1ccccc1 Show InChI InChI=1S/C33H44N6O5/c1-33(2,3)44-31(42)27(15-9-10-16-34)36-29(40)28(21-24-22-35-26-14-8-7-13-25(24)26)37-32(43)39-19-17-38(18-20-39)30(41)23-11-5-4-6-12-23/h4-8,11-14,22,27-28,35H,9-10,15-21,34H2,1-3H3,(H,36,40)(H,37,43)/t27-,28+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.90	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Inhibitory concentration of the compound towards binding of sst2 receptor using [125I]-somatostatin as radioligand in Neuro2A cells				Bioorg Med Chem Lett 11: 2731-4 (2001) BindingDB Entry DOI: 10.7270/Q2JW8D5S
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50105471 ((S)-6-Amino-2-((R)-3-(1H-indol-3-yl)-2-{[4-(toluen...) Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCN)C(=O)OC(C)(C)C Show InChI InChI=1S/C33H46N6O6S/c1-23-12-14-25(15-13-23)46(43,44)39-19-17-38(18-20-39)32(42)37-29(21-24-22-35-27-10-6-5-9-26(24)27)30(40)36-28(11-7-8-16-34)31(41)45-33(2,3)4/h5-6,9-10,12-15,22,28-29,35H,7-8,11,16-21,34H2,1-4H3,(H,36,40)(H,37,42)/t28-,29+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.20	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Inhibitory concentration of the compound towards binding of sst2 receptor using [125I]-somatostatin as radioligand in Neuro2A cells				Bioorg Med Chem Lett 11: 2731-4 (2001) BindingDB Entry DOI: 10.7270/Q2JW8D5S
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50105466 ((S)-6-Amino-2-[(R)-2-[(4-benzenesulfonyl-piperazin...) Show SMILES CC(C)(C)OC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)N1CCN(CC1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C32H44N6O6S/c1-32(2,3)44-30(40)27(15-9-10-16-33)35-29(39)28(21-23-22-34-26-14-8-7-13-25(23)26)36-31(41)37-17-19-38(20-18-37)45(42,43)24-11-5-4-6-12-24/h4-8,11-14,22,27-28,34H,9-10,15-21,33H2,1-3H3,(H,35,39)(H,36,41)/t27-,28+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Inhibitory concentration of the compound towards binding of sst2 receptor using [125I]-somatostatin as radioligand in Neuro2A cells				Bioorg Med Chem Lett 11: 2731-4 (2001) BindingDB Entry DOI: 10.7270/Q2JW8D5S
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50137438 (5-Methanesulfonyl-2-[5-(4-methoxy-phenyl)-3-triflu...) Show SMILES COc1ccc(cc1)-c1cc(nn1-c1ccc(cn1)S(C)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O3S/c1-26-12-5-3-11(4-6-12)14-9-15(17(18,19)20)22-23(14)16-8-7-13(10-21-16)27(2,24)25/h3-10H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50137423 (2-(4-Chloro-3-difluoromethyl-5-phenyl-pyrazol-1-yl...) Show SMILES CS(=O)(=O)c1ccc(nc1)-n1nc(C(F)F)c(Cl)c1-c1ccccc1 Show InChI InChI=1S/C16H12ClF2N3O2S/c1-25(23,24)11-7-8-12(20-9-11)22-15(10-5-3-2-4-6-10)13(17)14(21-22)16(18)19/h2-9,16H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Canis familiaris)	BDBM50137420 (2-[5-(4-Ethoxy-phenyl)-3-trifluoromethyl-pyrazol-1...) Show SMILES CCOc1ccc(cc1)-c1cc(nn1-c1ccc(cn1)S(C)(=O)=O)C(F)(F)F Show InChI InChI=1S/C18H16F3N3O3S/c1-3-27-13-6-4-12(5-7-13)15-10-16(18(19,20)21)23-24(15)17-9-8-14(11-22-17)28(2,25)26/h4-11H,3H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 1.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50137442 (2-[3-Difluoromethyl-5-(3-fluoro-4-methoxy-phenyl)-...) Show SMILES COc1ccc(cc1F)-c1cc(nn1-c1ccc(cn1)S(C)(=O)=O)C(F)F Show InChI InChI=1S/C17H14F3N3O3S/c1-26-15-5-3-10(7-12(15)18)14-8-13(17(19)20)22-23(14)16-6-4-11(9-21-16)27(2,24)25/h3-9,17H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50137439 (2-[5-(2-Fluoro-4-methoxy-phenyl)-3-trifluoromethyl...) Show SMILES COc1ccc(-c2cc(nn2-c2ccc(cn2)S(C)(=O)=O)C(F)(F)F)c(F)c1 Show InChI InChI=1S/C17H13F4N3O3S/c1-27-10-3-5-12(13(18)7-10)14-8-15(17(19,20)21)23-24(14)16-6-4-11(9-22-16)28(2,25)26/h3-9H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50137435 (2-(4-Chloro-5-phenyl-3-trifluoromethyl-pyrazol-1-y...) Show SMILES CS(=O)(=O)c1ccc(nc1)-n1nc(c(Cl)c1-c1ccccc1)C(F)(F)F Show InChI InChI=1S/C16H11ClF3N3O2S/c1-26(24,25)11-7-8-12(21-9-11)23-14(10-5-3-2-4-6-10)13(17)15(22-23)16(18,19)20/h2-9H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50137424 (2-[4-Chloro-5-(3-chloro-4-methoxy-phenyl)-3-difluo...) Show SMILES COc1ccc(cc1Cl)-c1c(Cl)c(nn1-c1ccc(cn1)S(C)(=O)=O)C(F)F Show InChI InChI=1S/C17H13Cl2F2N3O3S/c1-27-12-5-3-9(7-11(12)18)16-14(19)15(17(20)21)23-24(16)13-6-4-10(8-22-13)28(2,25)26/h3-8,17H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50137411 (2-[3-Difluoromethyl-5-(4-methoxy-phenyl)-pyrazol-1...) Show SMILES COc1ccc(cc1)-c1cc(nn1-c1ccc(cn1)S(C)(=O)=O)C(F)F Show InChI InChI=1S/C17H15F2N3O3S/c1-25-12-5-3-11(4-6-12)15-9-14(17(18)19)21-22(15)16-8-7-13(10-20-16)26(2,23)24/h3-10,17H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50105470 ((S)-6-Amino-2-((R)-3-(1H-indol-3-yl)-2-{[4-(4-meth...) Show SMILES Cc1ccc(cc1)C(=O)N1CCN(CC1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCN)C(=O)OC(C)(C)C Show InChI InChI=1S/C34H46N6O5/c1-23-12-14-24(15-13-23)31(42)39-17-19-40(20-18-39)33(44)38-29(21-25-22-36-27-10-6-5-9-26(25)27)30(41)37-28(11-7-8-16-35)32(43)45-34(2,3)4/h5-6,9-10,12-15,22,28-29,36H,7-8,11,16-21,35H2,1-4H3,(H,37,41)(H,38,44)/t28-,29+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Antagonistic activity of the compound towards sst2 receptor in GH4C1 cells a concentration of 1-2 x 10e6/mL incubated for 20 minutes				Bioorg Med Chem Lett 11: 2731-4 (2001) BindingDB Entry DOI: 10.7270/Q2JW8D5S
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50137437 (5-Methanesulfonyl-2-[5-(4-methylsulfanyl-phenyl)-3...) Show SMILES CSc1ccc(cc1)-c1cc(nn1-c1ccc(cn1)S(C)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S2/c1-26-12-5-3-11(4-6-12)14-9-15(17(18,19)20)22-23(14)16-8-7-13(10-21-16)27(2,24)25/h3-10H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50137427 (2-(4-Bromo-3-difluoromethyl-5-phenyl-pyrazol-1-yl)...) Show SMILES CS(=O)(=O)c1ccc(nc1)-n1nc(C(F)F)c(Br)c1-c1ccccc1 Show InChI InChI=1S/C16H12BrF2N3O2S/c1-25(23,24)11-7-8-12(20-9-11)22-15(10-5-3-2-4-6-10)13(17)14(21-22)16(18)19/h2-9,16H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50137428 (2-[3-Difluoromethyl-5-(4-methylsulfanyl-phenyl)-py...) Show SMILES CSc1ccc(cc1)-c1cc(nn1-c1ccc(cn1)S(C)(=O)=O)C(F)F Show InChI InChI=1S/C17H15F2N3O2S2/c1-25-12-5-3-11(4-6-12)15-9-14(17(18)19)21-22(15)16-8-7-13(10-20-16)26(2,23)24/h3-10,17H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50137414 (2-[5-(4-Chloro-phenyl)-3-difluoromethyl-pyrazol-1-...) Show SMILES CS(=O)(=O)c1ccc(nc1)-n1nc(cc1-c1ccc(Cl)cc1)C(F)F Show InChI InChI=1S/C16H12ClF2N3O2S/c1-25(23,24)12-6-7-15(20-9-12)22-14(8-13(21-22)16(18)19)10-2-4-11(17)5-3-10/h2-9,16H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50137440 (CHEMBL176934 | {4-[2-(5-Methanesulfonyl-pyridin-2-...) Show SMILES CN(C)c1ccc(cc1)-c1cc(nn1-c1ccc(cn1)S(C)(=O)=O)C(F)(F)F Show InChI InChI=1S/C18H17F3N4O2S/c1-24(2)13-6-4-12(5-7-13)15-10-16(18(19,20)21)23-25(15)17-9-8-14(11-22-17)28(3,26)27/h4-11H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50105472 ((S)-6-Amino-2-[(R)-2-[(1-benzenesulfonyl-piperidin...) Show SMILES CC(C)(C)OC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)C1CCN(CC1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C33H45N5O6S/c1-33(2,3)44-32(41)28(15-9-10-18-34)36-31(40)29(21-24-22-35-27-14-8-7-13-26(24)27)37-30(39)23-16-19-38(20-17-23)45(42,43)25-11-5-4-6-12-25/h4-8,11-14,22-23,28-29,35H,9-10,15-21,34H2,1-3H3,(H,36,40)(H,37,39)/t28-,29+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Antagonistic activity of the compound towards sst2 receptor in GH4C1 cells a concentration of 1-2 x 10e6/mL incubated for 20 minutes				Bioorg Med Chem Lett 11: 2731-4 (2001) BindingDB Entry DOI: 10.7270/Q2JW8D5S
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50137420 (2-[5-(4-Ethoxy-phenyl)-3-trifluoromethyl-pyrazol-1...) Show SMILES CCOc1ccc(cc1)-c1cc(nn1-c1ccc(cn1)S(C)(=O)=O)C(F)(F)F Show InChI InChI=1S/C18H16F3N3O3S/c1-3-27-13-6-4-12(5-7-13)15-10-16(18(19,20)21)23-24(15)17-9-8-14(11-22-17)28(2,25)26/h4-11H,3H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50137412 (5-Methanesulfonyl-2-(4-methyl-5-phenyl-3-trifluoro...) Show SMILES Cc1c(nn(c1-c1ccccc1)-c1ccc(cn1)S(C)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-15(12-6-4-3-5-7-12)23(22-16(11)17(18,19)20)14-9-8-13(10-21-14)26(2,24)25/h3-10H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50137434 (2-[3-Difluoromethyl-5-(4-methoxy-3-methyl-phenyl)-...) Show SMILES COc1ccc(cc1C)-c1cc(nn1-c1ccc(cn1)S(C)(=O)=O)C(F)F Show InChI InChI=1S/C18H17F2N3O3S/c1-11-8-12(4-6-16(11)26-2)15-9-14(18(19)20)22-23(15)17-7-5-13(10-21-17)27(3,24)25/h4-10,18H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50137418 (2-(3-Difluoromethyl-5-p-tolyl-pyrazol-1-yl)-5-meth...) Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cn1)S(C)(=O)=O)C(F)F Show InChI InChI=1S/C17H15F2N3O2S/c1-11-3-5-12(6-4-11)15-9-14(17(18)19)21-22(15)16-8-7-13(10-20-16)25(2,23)24/h3-10,17H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50137432 (2-(3-Difluoromethyl-4-methyl-5-phenyl-pyrazol-1-yl...) Show SMILES Cc1c(nn(c1-c1ccccc1)-c1ccc(cn1)S(C)(=O)=O)C(F)F Show InChI InChI=1S/C17H15F2N3O2S/c1-11-15(17(18)19)21-22(16(11)12-6-4-3-5-7-12)14-9-8-13(10-20-14)25(2,23)24/h3-10,17H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Canis familiaris)	BDBM50137411 (2-[3-Difluoromethyl-5-(4-methoxy-phenyl)-pyrazol-1...) Show SMILES COc1ccc(cc1)-c1cc(nn1-c1ccc(cn1)S(C)(=O)=O)C(F)F Show InChI InChI=1S/C17H15F2N3O3S/c1-25-12-5-3-11(4-6-12)15-9-14(17(18)19)21-22(15)16-8-7-13(10-20-16)26(2,23)24/h3-10,17H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 1.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50137416 (2-(5-(4-fluorophenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES CS(=O)(=O)c1ccc(nc1)-n1nc(cc1-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C16H11F4N3O2S/c1-26(24,25)12-6-7-15(21-9-12)23-13(8-14(22-23)16(18,19)20)10-2-4-11(17)5-3-10/h2-9H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50137413 (2-[5-(4-Chloro-phenyl)-3-trifluoromethyl-pyrazol-1...) Show SMILES CS(=O)(=O)c1ccc(nc1)-n1nc(cc1-c1ccc(Cl)cc1)C(F)(F)F Show InChI InChI=1S/C16H11ClF3N3O2S/c1-26(24,25)12-6-7-15(21-9-12)23-13(8-14(22-23)16(18,19)20)10-2-4-11(17)5-3-10/h2-9H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50105465 ((4R,8S,11S,17S)-8-(4-Amino-butyl)-17-(2-amino-3-na...) Show SMILES CC(C)(C)C1N[C@@H](CSSC[C@@H](NC(=O)C(N)Cc2cccc(F)c2)C(=O)NC(Cc2cccnc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C1=O)C(=O)NC(Cc1cccc2ccccc12)C(N)=O Show InChI InChI=1S/C58H70FN11O7S2/c1-58(2,3)51-50(71)44(22-8-9-23-60)66-55(75)47(29-38-31-64-43-21-7-6-20-41(38)43)69-54(74)46(27-35-14-12-24-63-30-35)68-57(77)49(70-53(73)42(61)26-34-13-10-18-39(59)25-34)33-79-78-32-48(65-51)56(76)67-45(52(62)72)28-37-17-11-16-36-15-4-5-19-40(36)37/h4-7,10-21,24-25,30-31,42,44-49,51,64-65H,8-9,22-23,26-29,32-33,60-61H2,1-3H3,(H2,62,72)(H,66,75)(H,67,76)(H,68,77)(H,69,74)(H,70,73)/t42?,44-,45?,46?,47-,48-,49+,51?/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Antagonistic activity of the compound towards sst2 receptor in GH4C1 cells a concentration of 1-2 x 10e6/mL incubated for 20 minutes				Bioorg Med Chem Lett 11: 2731-4 (2001) BindingDB Entry DOI: 10.7270/Q2JW8D5S
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50137415 (5-Methanesulfonyl-2-[5-(4-methoxy-3-methyl-phenyl)...) Show SMILES COc1ccc(cc1C)-c1cc(nn1-c1ccc(cn1)S(C)(=O)=O)C(F)(F)F Show InChI InChI=1S/C18H16F3N3O3S/c1-11-8-12(4-6-15(11)27-2)14-9-16(18(19,20)21)23-24(14)17-7-5-13(10-22-17)28(3,25)26/h4-10H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50137410 (2-[5-(4-Bromo-phenyl)-3-difluoromethyl-pyrazol-1-y...) Show SMILES CS(=O)(=O)c1ccc(nc1)-n1nc(cc1-c1ccc(Br)cc1)C(F)F Show InChI InChI=1S/C16H12BrF2N3O2S/c1-25(23,24)12-6-7-15(20-9-12)22-14(8-13(21-22)16(18)19)10-2-4-11(17)5-3-10/h2-9,16H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50137441 (2-[5-(3-Chloro-4-methoxy-phenyl)-3-trifluoromethyl...) Show SMILES COc1ccc(cc1Cl)-c1cc(nn1-c1ccc(cn1)S(C)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H13ClF3N3O3S/c1-27-14-5-3-10(7-12(14)18)13-8-15(17(19,20)21)23-24(13)16-6-4-11(9-22-16)28(2,25)26/h3-9H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50137429 (2-[3-Difluoromethyl-5-(4-fluoro-phenyl)-pyrazol-1-...) Show SMILES CS(=O)(=O)c1ccc(nc1)-n1nc(cc1-c1ccc(F)cc1)C(F)F Show InChI InChI=1S/C16H12F3N3O2S/c1-25(23,24)12-6-7-15(20-9-12)22-14(8-13(21-22)16(18)19)10-2-4-11(17)5-3-10/h2-9,16H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50137421 (2-[5-(3-Fluoro-4-methoxy-phenyl)-3-trifluoromethyl...) Show SMILES COc1ccc(cc1F)-c1cc(nn1-c1ccc(cn1)S(C)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H13F4N3O3S/c1-27-14-5-3-10(7-12(14)18)13-8-15(17(19,20)21)23-24(13)16-6-4-11(9-22-16)28(2,25)26/h3-9H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50137425 (2-(3-(difluoromethyl)-5-phenyl-1H-pyrazol-1-yl)-5-...) Show SMILES CS(=O)(=O)c1ccc(nc1)-n1nc(cc1-c1ccccc1)C(F)F Show InChI InChI=1S/C16H13F2N3O2S/c1-24(22,23)12-7-8-15(19-10-12)21-14(9-13(20-21)16(17)18)11-5-3-2-4-6-11/h2-10,16H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Canis familiaris)	BDBM50137423 (2-(4-Chloro-3-difluoromethyl-5-phenyl-pyrazol-1-yl...) Show SMILES CS(=O)(=O)c1ccc(nc1)-n1nc(C(F)F)c(Cl)c1-c1ccccc1 Show InChI InChI=1S/C16H12ClF2N3O2S/c1-25(23,24)11-7-8-12(20-9-11)22-15(10-5-3-2-4-6-10)13(17)14(21-22)16(18)19/h2-9,16H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 1.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50137436 (2-[5-(3-Chloro-4-methoxy-phenyl)-3-difluoromethyl-...) Show SMILES COc1ccc(cc1Cl)-c1cc(nn1-c1ccc(cn1)S(C)(=O)=O)C(F)F Show InChI InChI=1S/C17H14ClF2N3O3S/c1-26-15-5-3-10(7-12(15)18)14-8-13(17(19)20)22-23(14)16-6-4-11(9-21-16)27(2,24)25/h3-9,17H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50137422 (2-[3-Difluoromethyl-5-(2-fluoro-4-methoxy-phenyl)-...) Show SMILES COc1ccc(-c2cc(nn2-c2ccc(cn2)S(C)(=O)=O)C(F)F)c(F)c1 Show InChI InChI=1S/C17H14F3N3O3S/c1-26-10-3-5-12(13(18)7-10)15-8-14(17(19)20)22-23(15)16-6-4-11(9-21-16)27(2,24)25/h3-9,17H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50137417 (2-[3-Difluoromethyl-5-(4-ethyl-phenyl)-pyrazol-1-y...) Show SMILES CCc1ccc(cc1)-c1cc(nn1-c1ccc(cn1)S(C)(=O)=O)C(F)F Show InChI InChI=1S/C18H17F2N3O2S/c1-3-12-4-6-13(7-5-12)16-10-15(18(19)20)22-23(16)17-9-8-14(11-21-17)26(2,24)25/h4-11,18H,3H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50137433 (5-(methylsulfonyl)-2-(5-phenyl-3-(trifluoromethyl)...) Show SMILES CS(=O)(=O)c1ccc(nc1)-n1nc(cc1-c1ccccc1)C(F)(F)F Show InChI InChI=1S/C16H12F3N3O2S/c1-25(23,24)12-7-8-15(20-10-12)22-13(11-5-3-2-4-6-11)9-14(21-22)16(17,18)19/h2-10H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50137419 (2-[5-(4-Bromo-phenyl)-3-trifluoromethyl-pyrazol-1-...) Show SMILES CS(=O)(=O)c1ccc(nc1)-n1nc(cc1-c1ccc(Br)cc1)C(F)(F)F Show InChI InChI=1S/C16H11BrF3N3O2S/c1-26(24,25)12-6-7-15(21-9-12)23-13(8-14(22-23)16(18,19)20)10-2-4-11(17)5-3-10/h2-9H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50057583 (4-[3-Difluoromethyl-5-(3-fluoro-4-methoxy-phenyl)-...) Show SMILES COc1ccc(cc1F)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)F Show InChI InChI=1S/C17H14F3N3O3S/c1-26-16-7-2-10(8-13(16)18)15-9-14(17(19)20)22-23(15)11-3-5-12(6-4-11)27(21,24)25/h2-9,17H,1H3,(H2,21,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Canis familiaris)	BDBM50137438 (5-Methanesulfonyl-2-[5-(4-methoxy-phenyl)-3-triflu...) Show SMILES COc1ccc(cc1)-c1cc(nn1-c1ccc(cn1)S(C)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O3S/c1-26-12-5-3-11(4-6-12)14-9-15(17(18,19)20)22-23(14)16-8-7-13(10-21-16)27(2,24)25/h3-10H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 1.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Canis familiaris)	BDBM50137428 (2-[3-Difluoromethyl-5-(4-methylsulfanyl-phenyl)-py...) Show SMILES CSc1ccc(cc1)-c1cc(nn1-c1ccc(cn1)S(C)(=O)=O)C(F)F Show InChI InChI=1S/C17H15F2N3O2S2/c1-25-12-5-3-11(4-6-12)15-9-14(17(18)19)21-22(15)16-8-7-13(10-20-16)26(2,23)24/h3-10,17H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 1.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair				3D Structure (crystal)

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