Compile Data Set for Download or QSAR

Found 145 hits with Last Name = 'knippschild' and Initial = 'u'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-serine O-palmitoleoyltransferase porcupine (Homo sapiens (Human))	BDBM50133864 (CHEMBL2139947 | US10251893, Compound 59) Show SMILES Cc1cc(ccn1)-c1ccc(CC(=O)Nc2ccc(cc2)-c2cccnc2)cc1 Show InChI InChI=1S/C25H21N3O/c1-18-15-22(12-14-27-18)20-6-4-19(5-7-20)16-25(29)28-24-10-8-21(9-11-24)23-3-2-13-26-17-23/h2-15,17H,16H2,1H3,(H,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of porcupine in HEK293T cells transfected with Wnt3A-expressing vector assessed as suppression of Wnt/beta-catenin signaling after 22 hrs ...				J Med Chem 61: 4087-4102 (2018) Article DOI: 10.1021/acs.jmedchem.8b00095 BindingDB Entry DOI: 10.7270/Q2GX4F5D
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM50300884 ((E)-3-(2,4-Dimethoxy-phenyl)-N-(4-[5-(4-fluoro-phe...) Show SMILES COc1ccc(C=CC(=O)Nc2cc(ccn2)-c2nc(SC)[nH]c2-c2ccc(F)cc2)c(OC)c1 |w:6.5| Show InChI InChI=1S/C26H23FN4O3S/c1-33-20-10-6-16(21(15-20)34-2)7-11-23(32)29-22-14-18(12-13-28-22)25-24(30-26(31-25)35-3)17-4-8-19(27)9-5-17/h4-15H,1-3H3,(H,30,31)(H,28,29,32)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of recombinant CK1delta kinase domain by Cherenkov counting				J Med Chem 52: 7618-30 (2009) Article DOI: 10.1021/jm9005127 BindingDB Entry DOI: 10.7270/Q28K7961
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM50300893 ((E)-3-(2,4-Dimethoxy-phenyl)-N-(4-[5-(4-fluoro-phe...) Show SMILES COc1ccc(C=CC(=O)Nc2cc(ccn2)-c2nc([nH]c2-c2ccc(F)cc2)S(C)=O)c(OC)c1 |w:6.5| Show InChI InChI=1S/C26H23FN4O4S/c1-34-20-10-6-16(21(15-20)35-2)7-11-23(32)29-22-14-18(12-13-28-22)25-24(30-26(31-25)36(3)33)17-4-8-19(27)9-5-17/h4-15H,1-3H3,(H,30,31)(H,28,29,32)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of recombinant CK1delta kinase domain by Cherenkov counting				J Med Chem 52: 7618-30 (2009) Article DOI: 10.1021/jm9005127 BindingDB Entry DOI: 10.7270/Q28K7961
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Rattus norvegicus (rat))	BDBM50300884 ((E)-3-(2,4-Dimethoxy-phenyl)-N-(4-[5-(4-fluoro-phe...) Show SMILES COc1ccc(C=CC(=O)Nc2cc(ccn2)-c2nc(SC)[nH]c2-c2ccc(F)cc2)c(OC)c1 |w:6.5| Show InChI InChI=1S/C26H23FN4O3S/c1-33-20-10-6-16(21(15-20)34-2)7-11-23(32)29-22-14-18(12-13-28-22)25-24(30-26(31-25)35-3)17-4-8-19(27)9-5-17/h4-15H,1-3H3,(H,30,31)(H,28,29,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of GST-fused rat CK1delta by Cherenkov counting in presence of 20 uM ATP				J Med Chem 52: 7618-30 (2009) Article DOI: 10.1021/jm9005127 BindingDB Entry DOI: 10.7270/Q28K7961
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50300888 ((S)-4-(3-(4-fluorophenyl)-5-isopropylisoxazol-4-yl...) Show SMILES CC(C)c1onc(c1-c1ccnc(N[C@@H](C)c2ccccc2)c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C25H24FN3O/c1-16(2)25-23(24(29-30-25)19-9-11-21(26)12-10-19)20-13-14-27-22(15-20)28-17(3)18-7-5-4-6-8-18/h4-17H,1-3H3,(H,27,28)/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of p38alpha by Cherenkov counting				J Med Chem 52: 7618-30 (2009) Article DOI: 10.1021/jm9005127 BindingDB Entry DOI: 10.7270/Q28K7961
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Rattus norvegicus (rat))	BDBM50025019 (CHEMBL3337845) Show SMILES FC(F)(F)Oc1ccccc1C(=O)Nc1nc(cs1)C(=O)Nc1nc2cc3OC(F)(F)Oc3cc2[nH]1 Show InChI InChI=1S/C20H10F5N5O5S/c21-19(22,23)33-12-4-2-1-3-8(12)15(31)30-18-28-11(7-36-18)16(32)29-17-26-9-5-13-14(6-10(9)27-17)35-20(24,25)34-13/h1-7H,(H,28,30,31)(H2,26,27,29,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of rat CK1delta kinetic domain expressed in Escherichia coli using GST-p53 (1 to 64 residues) by SDS-PAGE based autoradiography				J Med Chem 57: 7933-46 (2014) Article DOI: 10.1021/jm500600b BindingDB Entry DOI: 10.7270/Q2N0183J
					More data for this Ligand-Target Pair				3D Structure (crystal)
Casein kinase I isoform delta (Rattus norvegicus (rat))	BDBM50300893 ((E)-3-(2,4-Dimethoxy-phenyl)-N-(4-[5-(4-fluoro-phe...) Show SMILES COc1ccc(C=CC(=O)Nc2cc(ccn2)-c2nc([nH]c2-c2ccc(F)cc2)S(C)=O)c(OC)c1 |w:6.5| Show InChI InChI=1S/C26H23FN4O4S/c1-34-20-10-6-16(21(15-20)35-2)7-11-23(32)29-22-14-18(12-13-28-22)25-24(30-26(31-25)36(3)33)17-4-8-19(27)9-5-17/h4-15H,1-3H3,(H,30,31)(H,28,29,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of GST-fused rat CK1delta by Cherenkov counting in presence of 20 uM ATP				J Med Chem 52: 7618-30 (2009) Article DOI: 10.1021/jm9005127 BindingDB Entry DOI: 10.7270/Q28K7961
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Rattus norvegicus (rat))	BDBM50025016 (CHEMBL3337849) Show SMILES CN(C)c1cccc(c1)C(=O)Nc1nc2cc3OC(F)(F)Oc3cc2[nH]1 Show InChI InChI=1S/C17H14F2N4O3/c1-23(2)10-5-3-4-9(6-10)15(24)22-16-20-11-7-13-14(8-12(11)21-16)26-17(18,19)25-13/h3-8H,1-2H3,(H2,20,21,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of rat CK1delta by radiometric protein kinase filter binding assay				J Med Chem 57: 7933-46 (2014) Article DOI: 10.1021/jm500600b BindingDB Entry DOI: 10.7270/Q2N0183J
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50300884 ((E)-3-(2,4-Dimethoxy-phenyl)-N-(4-[5-(4-fluoro-phe...) Show SMILES COc1ccc(C=CC(=O)Nc2cc(ccn2)-c2nc(SC)[nH]c2-c2ccc(F)cc2)c(OC)c1 |w:6.5| Show InChI InChI=1S/C26H23FN4O3S/c1-33-20-10-6-16(21(15-20)34-2)7-11-23(32)29-22-14-18(12-13-28-22)25-24(30-26(31-25)35-3)17-4-8-19(27)9-5-17/h4-15H,1-3H3,(H,30,31)(H,28,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of p38alpha by Cherenkov counting				J Med Chem 52: 7618-30 (2009) Article DOI: 10.1021/jm9005127 BindingDB Entry DOI: 10.7270/Q28K7961
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Rattus norvegicus (rat))	BDBM50025019 (CHEMBL3337845) Show SMILES FC(F)(F)Oc1ccccc1C(=O)Nc1nc(cs1)C(=O)Nc1nc2cc3OC(F)(F)Oc3cc2[nH]1 Show InChI InChI=1S/C20H10F5N5O5S/c21-19(22,23)33-12-4-2-1-3-8(12)15(31)30-18-28-11(7-36-18)16(32)29-17-26-9-5-13-14(6-10(9)27-17)35-20(24,25)34-13/h1-7H,(H,28,30,31)(H2,26,27,29,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of GST-tagged rat CK1delta expressed in Escherichia coli using GST-p53 (1 to 64 residues) by SDS-PAGE based autoradiography				J Med Chem 57: 7933-46 (2014) Article DOI: 10.1021/jm500600b BindingDB Entry DOI: 10.7270/Q2N0183J
					More data for this Ligand-Target Pair				3D Structure (crystal)
Casein kinase I isoform delta (Rattus norvegicus (rat))	BDBM50025019 (CHEMBL3337845) Show SMILES FC(F)(F)Oc1ccccc1C(=O)Nc1nc(cs1)C(=O)Nc1nc2cc3OC(F)(F)Oc3cc2[nH]1 Show InChI InChI=1S/C20H10F5N5O5S/c21-19(22,23)33-12-4-2-1-3-8(12)15(31)30-18-28-11(7-36-18)16(32)29-17-26-9-5-13-14(6-10(9)27-17)35-20(24,25)34-13/h1-7H,(H,28,30,31)(H2,26,27,29,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of rat CK1delta kinetic domain expressed in Escherichia coli using alpha casein substrate by SDS-PAGE based autoradiography				J Med Chem 57: 7933-46 (2014) Article DOI: 10.1021/jm500600b BindingDB Entry DOI: 10.7270/Q2N0183J
					More data for this Ligand-Target Pair				3D Structure (crystal)
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM50025020 (CHEMBL3337854) Show SMILES FC(F)(F)Oc1ccccc1C(=O)Nc1nc(cs1)C(=O)Nc1nc2ccc(cc2[nH]1)C(F)(F)F Show InChI InChI=1S/C20H11F6N5O3S/c21-19(22,23)9-5-6-11-12(7-9)28-17(27-11)30-16(33)13-8-35-18(29-13)31-15(32)10-3-1-2-4-14(10)34-20(24,25)26/h1-8H,(H,29,31,32)(H2,27,28,30,33)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of human CK1delta transcription variant 1 using GST-tagged mouse p53 (1 to 64 residues) as substrate in presence of radiolabelled-ATP by C...				J Med Chem 61: 4087-4102 (2018) Article DOI: 10.1021/acs.jmedchem.8b00095 BindingDB Entry DOI: 10.7270/Q2GX4F5D
					More data for this Ligand-Target Pair				3D Structure (crystal)
Casein kinase I isoform delta (Rattus norvegicus (rat))	BDBM50025020 (CHEMBL3337854) Show SMILES FC(F)(F)Oc1ccccc1C(=O)Nc1nc(cs1)C(=O)Nc1nc2ccc(cc2[nH]1)C(F)(F)F Show InChI InChI=1S/C20H11F6N5O3S/c21-19(22,23)9-5-6-11-12(7-9)28-17(27-11)30-16(33)13-8-35-18(29-13)31-15(32)10-3-1-2-4-14(10)34-20(24,25)26/h1-8H,(H,29,31,32)(H2,27,28,30,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of rat CK1delta kinetic domain expressed in Escherichia coli using GST-p53 (1 to 64 residues) by SDS-PAGE based autoradiography				J Med Chem 57: 7933-46 (2014) Article DOI: 10.1021/jm500600b BindingDB Entry DOI: 10.7270/Q2N0183J
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50300885 (CHEMBL569551 | N-sec-butyl-4-(3-(4-fluorophenyl)-5...) Show SMILES CCC(C)Nc1cc(ccn1)-c1c(noc1C(C)C)-c1ccc(F)cc1 Show InChI InChI=1S/C21H24FN3O/c1-5-14(4)24-18-12-16(10-11-23-18)19-20(25-26-21(19)13(2)3)15-6-8-17(22)9-7-15/h6-14H,5H2,1-4H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of p38alpha by Cherenkov counting				J Med Chem 52: 7618-30 (2009) Article DOI: 10.1021/jm9005127 BindingDB Entry DOI: 10.7270/Q28K7961
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM50300892 ((E)-3-(2,4-dimethoxyphenyl)-N-(4-(3-(4-fluoropheny...) Show SMILES COc1ccc(\C=C\C(=O)Nc2cc(ccn2)-c2c(noc2C(C)C)-c2ccc(F)cc2)c(OC)c1 Show InChI InChI=1S/C28H26FN3O4/c1-17(2)28-26(27(32-36-28)19-5-9-21(29)10-6-19)20-13-14-30-24(15-20)31-25(33)12-8-18-7-11-22(34-3)16-23(18)35-4/h5-17H,1-4H3,(H,30,31,33)/b12-8+	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of recombinant CK1delta kinase domain by Cherenkov counting				J Med Chem 52: 7618-30 (2009) Article DOI: 10.1021/jm9005127 BindingDB Entry DOI: 10.7270/Q28K7961
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Rattus norvegicus (rat))	BDBM50025015 (CHEMBL3337846) Show SMILES COc1cccc(c1)C(=O)Nc1nc2cc3OC(F)(F)Oc3cc2[nH]1 Show InChI InChI=1S/C16H11F2N3O4/c1-23-9-4-2-3-8(5-9)14(22)21-15-19-10-6-12-13(7-11(10)20-15)25-16(17,18)24-12/h2-7H,1H3,(H2,19,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of rat CK1delta by radiometric protein kinase filter binding assay				J Med Chem 57: 7933-46 (2014) Article DOI: 10.1021/jm500600b BindingDB Entry DOI: 10.7270/Q2N0183J
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Rattus norvegicus (rat))	BDBM50428028 (CHEMBL1257064) Show SMILES Cc1ccc2nc(NC(=O)CSc3nc4CCSc4c(=O)n3-c3ccccc3)sc2c1 Show InChI InChI=1S/C22H18N4O2S3/c1-13-7-8-15-17(11-13)31-21(23-15)25-18(27)12-30-22-24-16-9-10-29-19(16)20(28)26(22)14-5-3-2-4-6-14/h2-8,11H,9-10,12H2,1H3,(H,23,25,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of rat GST-tagged CK1delta M82F mutant at 10 uM using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov ...				J Med Chem 61: 4087-4102 (2018) Article DOI: 10.1021/acs.jmedchem.8b00095 BindingDB Entry DOI: 10.7270/Q2GX4F5D
					More data for this Ligand-Target Pair				3D Structure (crystal)
Casein kinase I isoform delta (Rattus norvegicus (rat))	BDBM50025020 (CHEMBL3337854) Show SMILES FC(F)(F)Oc1ccccc1C(=O)Nc1nc(cs1)C(=O)Nc1nc2ccc(cc2[nH]1)C(F)(F)F Show InChI InChI=1S/C20H11F6N5O3S/c21-19(22,23)9-5-6-11-12(7-9)28-17(27-11)30-16(33)13-8-35-18(29-13)31-15(32)10-3-1-2-4-14(10)34-20(24,25)26/h1-8H,(H,29,31,32)(H2,27,28,30,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of rat recombinant GST-tagged CK1delta using GST-tagged mouse p53 (1 to 64 residues) as substrate in presence of radiolabelled-ATP by Cher...				J Med Chem 61: 4087-4102 (2018) Article DOI: 10.1021/acs.jmedchem.8b00095 BindingDB Entry DOI: 10.7270/Q2GX4F5D
					More data for this Ligand-Target Pair				3D Structure (crystal)
Casein kinase I isoform delta (Rattus norvegicus (rat))	BDBM50025020 (CHEMBL3337854) Show SMILES FC(F)(F)Oc1ccccc1C(=O)Nc1nc(cs1)C(=O)Nc1nc2ccc(cc2[nH]1)C(F)(F)F Show InChI InChI=1S/C20H11F6N5O3S/c21-19(22,23)9-5-6-11-12(7-9)28-17(27-11)30-16(33)13-8-35-18(29-13)31-15(32)10-3-1-2-4-14(10)34-20(24,25)26/h1-8H,(H,29,31,32)(H2,27,28,30,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of GST-tagged rat CK1delta expressed in Escherichia coli using GST-p53 (1 to 64 residues) by SDS-PAGE based autoradiography				J Med Chem 57: 7933-46 (2014) Article DOI: 10.1021/jm500600b BindingDB Entry DOI: 10.7270/Q2N0183J
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM13336 (4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...) Show SMILES CS(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C21H16FN3OS/c1-27(26)18-8-4-16(5-9-18)21-24-19(14-2-6-17(22)7-3-14)20(25-21)15-10-12-23-13-11-15/h2-13H,1H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of p38alpha by Cherenkov counting				J Med Chem 52: 7618-30 (2009) Article DOI: 10.1021/jm9005127 BindingDB Entry DOI: 10.7270/Q28K7961
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50300893 ((E)-3-(2,4-Dimethoxy-phenyl)-N-(4-[5-(4-fluoro-phe...) Show SMILES COc1ccc(C=CC(=O)Nc2cc(ccn2)-c2nc([nH]c2-c2ccc(F)cc2)S(C)=O)c(OC)c1 |w:6.5| Show InChI InChI=1S/C26H23FN4O4S/c1-34-20-10-6-16(21(15-20)35-2)7-11-23(32)29-22-14-18(12-13-28-22)25-24(30-26(31-25)36(3)33)17-4-8-19(27)9-5-17/h4-15H,1-3H3,(H,30,31)(H,28,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of p38alpha by Cherenkov counting				J Med Chem 52: 7618-30 (2009) Article DOI: 10.1021/jm9005127 BindingDB Entry DOI: 10.7270/Q28K7961
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM50025020 (CHEMBL3337854) Show SMILES FC(F)(F)Oc1ccccc1C(=O)Nc1nc(cs1)C(=O)Nc1nc2ccc(cc2[nH]1)C(F)(F)F Show InChI InChI=1S/C20H11F6N5O3S/c21-19(22,23)9-5-6-11-12(7-9)28-17(27-11)30-16(33)13-8-35-18(29-13)31-15(32)10-3-1-2-4-14(10)34-20(24,25)26/h1-8H,(H,29,31,32)(H2,27,28,30,33)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of human CK1delta transcription variant 2 using GST-tagged mouse p53 (1 to 64 residues) as substrate in presence of radiolabelled-ATP by C...				J Med Chem 61: 4087-4102 (2018) Article DOI: 10.1021/acs.jmedchem.8b00095 BindingDB Entry DOI: 10.7270/Q2GX4F5D
					More data for this Ligand-Target Pair				3D Structure (crystal)
Casein kinase I isoform delta (Rattus norvegicus (rat))	BDBM50300892 ((E)-3-(2,4-dimethoxyphenyl)-N-(4-(3-(4-fluoropheny...) Show SMILES COc1ccc(\C=C\C(=O)Nc2cc(ccn2)-c2c(noc2C(C)C)-c2ccc(F)cc2)c(OC)c1 Show InChI InChI=1S/C28H26FN3O4/c1-17(2)28-26(27(32-36-28)19-5-9-21(29)10-6-19)20-13-14-30-24(15-20)31-25(33)12-8-18-7-11-22(34-3)16-23(18)35-4/h5-17H,1-4H3,(H,30,31,33)/b12-8+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of GST-fused rat CK1delta by Cherenkov counting in presence of 20 uM ATP				J Med Chem 52: 7618-30 (2009) Article DOI: 10.1021/jm9005127 BindingDB Entry DOI: 10.7270/Q28K7961
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM13531 (4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridy...) Show SMILES Oc1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C20H14FN3O/c21-16-5-1-13(2-6-16)18-19(14-9-11-22-12-10-14)24-20(23-18)15-3-7-17(25)8-4-15/h1-12,25H,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of p38alpha by Cherenkov counting				J Med Chem 52: 7618-30 (2009) Article DOI: 10.1021/jm9005127 BindingDB Entry DOI: 10.7270/Q28K7961
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50300886 (4-(3-(4-fluorophenyl)-5-isopropylisoxazol-4-yl)-N-...) Show SMILES CC(C)c1onc(c1-c1ccnc(NC2CCOCC2)c1)-c1ccc(F)cc1 Show InChI InChI=1S/C22H24FN3O2/c1-14(2)22-20(21(26-28-22)15-3-5-17(23)6-4-15)16-7-10-24-19(13-16)25-18-8-11-27-12-9-18/h3-7,10,13-14,18H,8-9,11-12H2,1-2H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of p38alpha by Cherenkov counting				J Med Chem 52: 7618-30 (2009) Article DOI: 10.1021/jm9005127 BindingDB Entry DOI: 10.7270/Q28K7961
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Rattus norvegicus (rat))	BDBM50455468 (CHEMBL1257114) Show SMILES Cc1ccc2nc(NC(=O)CSc3nc4CCSc4c(=O)n3Cc3ccccc3)sc2c1 Show InChI InChI=1S/C23H20N4O2S3/c1-14-7-8-16-18(11-14)32-22(24-16)26-19(28)13-31-23-25-17-9-10-30-20(17)21(29)27(23)12-15-5-3-2-4-6-15/h2-8,11H,9-10,12-13H2,1H3,(H,24,26,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of rat GST-tagged CK1delta M82F mutant at 10 uM using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov ...				J Med Chem 61: 4087-4102 (2018) Article DOI: 10.1021/acs.jmedchem.8b00095 BindingDB Entry DOI: 10.7270/Q2GX4F5D
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Rattus norvegicus (rat))	BDBM50025015 (CHEMBL3337846) Show SMILES COc1cccc(c1)C(=O)Nc1nc2cc3OC(F)(F)Oc3cc2[nH]1 Show InChI InChI=1S/C16H11F2N3O4/c1-23-9-4-2-3-8(5-9)14(22)21-15-19-10-6-12-13(7-11(10)20-15)25-16(17,18)24-12/h2-7H,1H3,(H2,19,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of rat CK1delta kinetic domain expressed in Escherichia coli using GST-p53 (1 to 64 residues) by SDS-PAGE based autoradiography				J Med Chem 57: 7933-46 (2014) Article DOI: 10.1021/jm500600b BindingDB Entry DOI: 10.7270/Q2N0183J
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Rattus norvegicus (rat))	BDBM50025019 (CHEMBL3337845) Show SMILES FC(F)(F)Oc1ccccc1C(=O)Nc1nc(cs1)C(=O)Nc1nc2cc3OC(F)(F)Oc3cc2[nH]1 Show InChI InChI=1S/C20H10F5N5O5S/c21-19(22,23)33-12-4-2-1-3-8(12)15(31)30-18-28-11(7-36-18)16(32)29-17-26-9-5-13-14(6-10(9)27-17)35-20(24,25)34-13/h1-7H,(H,28,30,31)(H2,26,27,29,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of GST-tagged rat CK1delta expressed in Escherichia coli using alpha casein substrate by SDS-PAGE based autoradiography				J Med Chem 57: 7933-46 (2014) Article DOI: 10.1021/jm500600b BindingDB Entry DOI: 10.7270/Q2N0183J
					More data for this Ligand-Target Pair				3D Structure (crystal)
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50300884 ((E)-3-(2,4-Dimethoxy-phenyl)-N-(4-[5-(4-fluoro-phe...) Show SMILES COc1ccc(C=CC(=O)Nc2cc(ccn2)-c2nc(SC)[nH]c2-c2ccc(F)cc2)c(OC)c1 |w:6.5| Show InChI InChI=1S/C26H23FN4O3S/c1-33-20-10-6-16(21(15-20)34-2)7-11-23(32)29-22-14-18(12-13-28-22)25-24(30-26(31-25)35-3)17-4-8-19(27)9-5-17/h4-15H,1-3H3,(H,30,31)(H,28,29,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of recombinant CK1epsilon by Cherenkov counting in presence of 20 uM ATP				J Med Chem 52: 7618-30 (2009) Article DOI: 10.1021/jm9005127 BindingDB Entry DOI: 10.7270/Q28K7961
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Rattus norvegicus (rat))	BDBM50455466 (CHEMBL4204681) Show SMILES COc1ccc(Cn2c(SCC(=O)Nc3nc4ccc(cc4s3)C(F)(F)F)nc3CCSc3c2=O)cc1 Show InChI InChI=1S/C24H19F3N4O3S3/c1-34-15-5-2-13(3-6-15)11-31-21(33)20-17(8-9-35-20)29-23(31)36-12-19(32)30-22-28-16-7-4-14(24(25,26)27)10-18(16)37-22/h2-7,10H,8-9,11-12H2,1H3,(H,28,30,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of rat GST-tagged CK1delta M82F mutant at 10 uM using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov ...				J Med Chem 61: 4087-4102 (2018) Article DOI: 10.1021/acs.jmedchem.8b00095 BindingDB Entry DOI: 10.7270/Q2GX4F5D
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Rattus norvegicus (rat))	BDBM50455466 (CHEMBL4204681) Show SMILES COc1ccc(Cn2c(SCC(=O)Nc3nc4ccc(cc4s3)C(F)(F)F)nc3CCSc3c2=O)cc1 Show InChI InChI=1S/C24H19F3N4O3S3/c1-34-15-5-2-13(3-6-15)11-31-21(33)20-17(8-9-35-20)29-23(31)36-12-19(32)30-22-28-16-7-4-14(24(25,26)27)10-18(16)37-22/h2-7,10H,8-9,11-12H2,1H3,(H,28,30,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of rat recombinant CK1delta kinase domain using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counti...				J Med Chem 61: 4087-4102 (2018) Article DOI: 10.1021/acs.jmedchem.8b00095 BindingDB Entry DOI: 10.7270/Q2GX4F5D
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Rattus norvegicus (rat))	BDBM50300890 (2-(4-fluorophenyl)-N-(4-(3-(4-fluorophenyl)-5-isop...) Show SMILES CC(C)c1onc(c1-c1ccnc(NC(=O)Cc2ccc(F)cc2)c1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H21F2N3O2/c1-15(2)25-23(24(30-32-25)17-5-9-20(27)10-6-17)18-11-12-28-21(14-18)29-22(31)13-16-3-7-19(26)8-4-16/h3-12,14-15H,13H2,1-2H3,(H,28,29,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of GST-fused rat CK1delta by Cherenkov counting in presence of 20 uM ATP				J Med Chem 52: 7618-30 (2009) Article DOI: 10.1021/jm9005127 BindingDB Entry DOI: 10.7270/Q28K7961
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Rattus norvegicus (rat))	BDBM50025017 (CHEMBL3337855) Show SMILES COc1ccc(cc1)C(=O)Nc1nc2cc3OC(F)(F)Oc3cc2[nH]1 Show InChI InChI=1S/C16H11F2N3O4/c1-23-9-4-2-8(3-5-9)14(22)21-15-19-10-6-12-13(7-11(10)20-15)25-16(17,18)24-12/h2-7H,1H3,(H2,19,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	106	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of rat CK1delta by radiometric protein kinase filter binding assay				J Med Chem 57: 7933-46 (2014) Article DOI: 10.1021/jm500600b BindingDB Entry DOI: 10.7270/Q2N0183J
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50004566 (9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinaz...) Show SMILES Nc1nc2ccc(Cl)cc2c2nc(nn12)-c1ccco1 Show InChI InChI=1S/C13H8ClN5O/c14-7-3-4-9-8(6-7)12-17-11(10-2-1-5-20-10)18-19(12)13(15)16-9/h1-6H,(H2,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01199 BindingDB Entry DOI: 10.7270/Q2FX7FFT
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM50300890 (2-(4-fluorophenyl)-N-(4-(3-(4-fluorophenyl)-5-isop...) Show SMILES CC(C)c1onc(c1-c1ccnc(NC(=O)Cc2ccc(F)cc2)c1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H21F2N3O2/c1-15(2)25-23(24(30-32-25)17-5-9-20(27)10-6-17)18-11-12-28-21(14-18)29-22(31)13-16-3-7-19(26)8-4-16/h3-12,14-15H,13H2,1-2H3,(H,28,29,31)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of recombinant CK1delta kinase domain by Cherenkov counting				J Med Chem 52: 7618-30 (2009) Article DOI: 10.1021/jm9005127 BindingDB Entry DOI: 10.7270/Q28K7961
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM50588635 (CHEMBL5186013) Show SMILES Nc1nc2ccc(Br)cc2c2nc(nn12)-c1ccco1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01199 BindingDB Entry DOI: 10.7270/Q2FX7FFT
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM13336 (4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...) Show SMILES CS(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C21H16FN3OS/c1-27(26)18-8-4-16(5-9-18)21-24-19(14-2-6-17(22)7-3-14)20(25-21)15-10-12-23-13-11-15/h2-13H,1H3,(H,24,25)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of CK1delta by Cherenkov counting in presence of 20 uM ATP				J Med Chem 52: 7618-30 (2009) Article DOI: 10.1021/jm9005127 BindingDB Entry DOI: 10.7270/Q28K7961
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Rattus norvegicus (rat))	BDBM50025015 (CHEMBL3337846) Show SMILES COc1cccc(c1)C(=O)Nc1nc2cc3OC(F)(F)Oc3cc2[nH]1 Show InChI InChI=1S/C16H11F2N3O4/c1-23-9-4-2-3-8(5-9)14(22)21-15-19-10-6-12-13(7-11(10)20-15)25-16(17,18)24-12/h2-7H,1H3,(H2,19,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of GST-tagged rat CK1delta expressed in Escherichia coli using alpha casein substrate by SDS-PAGE based autoradiography				J Med Chem 57: 7933-46 (2014) Article DOI: 10.1021/jm500600b BindingDB Entry DOI: 10.7270/Q2N0183J
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Rattus norvegicus (rat))	BDBM50025024 (CHEMBL3337850) Show SMILES CN(C)c1cc(ccn1)C(=O)Nc1nc2cc3OC(F)(F)Oc3cc2[nH]1 Show InChI InChI=1S/C16H13F2N5O3/c1-23(2)13-5-8(3-4-19-13)14(24)22-15-20-9-6-11-12(7-10(9)21-15)26-16(17,18)25-11/h3-7H,1-2H3,(H2,20,21,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of GST-tagged rat CK1delta expressed in Escherichia coli using GST-p53 (1 to 64 residues) by SDS-PAGE based autoradiography				J Med Chem 57: 7933-46 (2014) Article DOI: 10.1021/jm500600b BindingDB Entry DOI: 10.7270/Q2N0183J
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Rattus norvegicus (rat))	BDBM50428027 (CHEMBL1257090) Show SMILES COc1ccccc1-n1c(SCC(=O)Nc2nc3ccc(C)cc3s2)nc2CCSc2c1=O |(3.46,-37.28,;2.64,-35.97,;3.36,-34.61,;4.9,-34.56,;5.62,-33.19,;4.79,-31.89,;3.26,-31.95,;2.54,-33.31,;1.01,-33.36,;.18,-32.06,;.9,-30.7,;2.44,-30.65,;3.16,-29.28,;4.7,-29.23,;2.34,-27.98,;.8,-28.04,;-.15,-26.82,;-1.59,-27.36,;-2.95,-26.64,;-4.25,-27.46,;-4.19,-29,;-5.49,-29.82,;-2.83,-29.71,;-1.54,-28.9,;-.06,-29.32,;-1.36,-32.12,;-2.08,-33.46,;-3.58,-33.83,;-3.7,-35.38,;-2.26,-35.96,;-1.26,-34.78,;.28,-34.72,;1.09,-36.03,)| Show InChI InChI=1S/C23H20N4O3S3/c1-13-7-8-14-18(11-13)33-22(24-14)26-19(28)12-32-23-25-15-9-10-31-20(15)21(29)27(23)16-5-3-4-6-17(16)30-2/h3-8,11H,9-10,12H2,1-2H3,(H,24,26,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of rat GST-tagged CK1delta M82F mutant at 10 uM using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov ...				J Med Chem 61: 4087-4102 (2018) Article DOI: 10.1021/acs.jmedchem.8b00095 BindingDB Entry DOI: 10.7270/Q2GX4F5D
					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50004566 (9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinaz...) Show SMILES Nc1nc2ccc(Cl)cc2c2nc(nn12)-c1ccco1 Show InChI InChI=1S/C13H8ClN5O/c14-7-3-4-9-8(6-7)12-17-11(10-2-1-5-20-10)18-19(12)13(15)16-9/h1-6H,(H2,15,16)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01199 BindingDB Entry DOI: 10.7270/Q2FX7FFT
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Rattus norvegicus (rat))	BDBM50025015 (CHEMBL3337846) Show SMILES COc1cccc(c1)C(=O)Nc1nc2cc3OC(F)(F)Oc3cc2[nH]1 Show InChI InChI=1S/C16H11F2N3O4/c1-23-9-4-2-3-8(5-9)14(22)21-15-19-10-6-12-13(7-11(10)20-15)25-16(17,18)24-12/h2-7H,1H3,(H2,19,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of GST-tagged rat CK1delta expressed in Escherichia coli using GST-p53 (1 to 64 residues) by SDS-PAGE based autoradiography				J Med Chem 57: 7933-46 (2014) Article DOI: 10.1021/jm500600b BindingDB Entry DOI: 10.7270/Q2N0183J
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Rattus norvegicus (rat))	BDBM50365355 (CHEMBL1257089) Show SMILES Cc1ccc2nc(NC(=O)CSc3nc4CCSc4c(=O)n3-c3ccc(F)cc3)sc2c1 Show InChI InChI=1S/C22H17FN4O2S3/c1-12-2-7-15-17(10-12)32-21(24-15)26-18(28)11-31-22-25-16-8-9-30-19(16)20(29)27(22)14-5-3-13(23)4-6-14/h2-7,10H,8-9,11H2,1H3,(H,24,26,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of rat GST-tagged CK1delta M82F mutant at 10 uM using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov ...				J Med Chem 61: 4087-4102 (2018) Article DOI: 10.1021/acs.jmedchem.8b00095 BindingDB Entry DOI: 10.7270/Q2GX4F5D
					More data for this Ligand-Target Pair
Protein-serine O-palmitoleoyltransferase porcupine (Homo sapiens (Human))	BDBM50428028 (CHEMBL1257064) Show SMILES Cc1ccc2nc(NC(=O)CSc3nc4CCSc4c(=O)n3-c3ccccc3)sc2c1 Show InChI InChI=1S/C22H18N4O2S3/c1-13-7-8-15-17(11-13)31-21(23-15)25-18(27)12-30-22-24-16-9-10-29-19(16)20(28)26(22)14-5-3-2-4-6-14/h2-8,11H,9-10,12H2,1H3,(H,23,25,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	157	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of porcupine in HEK293T cells transfected with Wnt3A-expressing vector assessed as suppression of Wnt/beta-catenin signaling after 22 hrs ...				J Med Chem 61: 4087-4102 (2018) Article DOI: 10.1021/acs.jmedchem.8b00095 BindingDB Entry DOI: 10.7270/Q2GX4F5D
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50025015 (CHEMBL3337846) Show SMILES COc1cccc(c1)C(=O)Nc1nc2cc3OC(F)(F)Oc3cc2[nH]1 Show InChI InChI=1S/C16H11F2N3O4/c1-23-9-4-2-3-8(5-9)14(22)21-15-19-10-6-12-13(7-11(10)20-15)25-16(17,18)24-12/h2-7H,1H3,(H2,19,20,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of human recombinant CK1epsilon expressed in Escherichia coli using alpha casein substrate by SDS-PAGE based autoradiography				J Med Chem 57: 7933-46 (2014) Article DOI: 10.1021/jm500600b BindingDB Entry DOI: 10.7270/Q2N0183J
					More data for this Ligand-Target Pair
Casein kinase I isoform alpha (Bos taurus)	BDBM50025019 (CHEMBL3337845) Show SMILES FC(F)(F)Oc1ccccc1C(=O)Nc1nc(cs1)C(=O)Nc1nc2cc3OC(F)(F)Oc3cc2[nH]1 Show InChI InChI=1S/C20H10F5N5O5S/c21-19(22,23)33-12-4-2-1-3-8(12)15(31)30-18-28-11(7-36-18)16(32)29-17-26-9-5-13-14(6-10(9)27-17)35-20(24,25)34-13/h1-7H,(H,28,30,31)(H2,26,27,29,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of GST-tagged bovine CK1alpha expressed in Escherichia coli using alpha casein substrate by SDS-PAGE based autoradiography				J Med Chem 57: 7933-46 (2014) Article DOI: 10.1021/jm500600b BindingDB Entry DOI: 10.7270/Q2N0183J
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Rattus norvegicus (rat))	BDBM50025015 (CHEMBL3337846) Show SMILES COc1cccc(c1)C(=O)Nc1nc2cc3OC(F)(F)Oc3cc2[nH]1 Show InChI InChI=1S/C16H11F2N3O4/c1-23-9-4-2-3-8(5-9)14(22)21-15-19-10-6-12-13(7-11(10)20-15)25-16(17,18)24-12/h2-7H,1H3,(H2,19,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of rat CK1delta kinetic domain expressed in Escherichia coli using alpha casein substrate by SDS-PAGE based autoradiography				J Med Chem 57: 7933-46 (2014) Article DOI: 10.1021/jm500600b BindingDB Entry DOI: 10.7270/Q2N0183J
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Rattus norvegicus (rat))	BDBM50025023 (CHEMBL3337851) Show SMILES FC(F)Oc1cccc(c1)C(=O)Nc1nc2cc3OC(F)(F)Oc3cc2[nH]1 Show InChI InChI=1S/C16H9F4N3O4/c17-14(18)25-8-3-1-2-7(4-8)13(24)23-15-21-9-5-11-12(6-10(9)22-15)27-16(19,20)26-11/h1-6,14H,(H2,21,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of rat CK1delta kinetic domain expressed in Escherichia coli using GST-p53 (1 to 64 residues) by SDS-PAGE based autoradiography				J Med Chem 57: 7933-46 (2014) Article DOI: 10.1021/jm500600b BindingDB Entry DOI: 10.7270/Q2N0183J
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Rattus norvegicus (rat))	BDBM50025016 (CHEMBL3337849) Show SMILES CN(C)c1cccc(c1)C(=O)Nc1nc2cc3OC(F)(F)Oc3cc2[nH]1 Show InChI InChI=1S/C17H14F2N4O3/c1-23(2)10-5-3-4-9(6-10)15(24)22-16-20-11-7-13-14(8-12(11)21-16)26-17(18,19)25-13/h3-8H,1-2H3,(H2,20,21,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of rat CK1delta kinetic domain expressed in Escherichia coli using GST-p53 (1 to 64 residues) by SDS-PAGE based autoradiography				J Med Chem 57: 7933-46 (2014) Article DOI: 10.1021/jm500600b BindingDB Entry DOI: 10.7270/Q2N0183J
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50025019 (CHEMBL3337845) Show SMILES FC(F)(F)Oc1ccccc1C(=O)Nc1nc(cs1)C(=O)Nc1nc2cc3OC(F)(F)Oc3cc2[nH]1 Show InChI InChI=1S/C20H10F5N5O5S/c21-19(22,23)33-12-4-2-1-3-8(12)15(31)30-18-28-11(7-36-18)16(32)29-17-26-9-5-13-14(6-10(9)27-17)35-20(24,25)34-13/h1-7H,(H,28,30,31)(H2,26,27,29,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of human recombinant CK1epsilon expressed in Escherichia coli using alpha casein substrate by SDS-PAGE based autoradiography				J Med Chem 57: 7933-46 (2014) Article DOI: 10.1021/jm500600b BindingDB Entry DOI: 10.7270/Q2N0183J
					More data for this Ligand-Target Pair				3D Structure (crystal)

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