Compile Data Set for Download or QSAR

Found 43 hits with Last Name = 'lasek' and Initial = 'aw'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM50514279 (CHEMBL4527655) Show SMILES CC1CN(CCOc2ccc(Oc3c(sc4cc(O)ccc34)C(=O)c3ccccc3C)cc2)C1 Show InChI InChI=1S/C28H27NO4S/c1-18-16-29(17-18)13-14-32-21-8-10-22(11-9-21)33-27-24-12-7-20(30)15-25(24)34-28(27)26(31)23-6-4-3-5-19(23)2/h3-12,15,18,30H,13-14,16-17H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.257	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assay				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50514280 (CHEMBL4586663) Show SMILES Oc1ccc2c(Oc3ccc(OC4CN(CCCF)C4)cc3)c(sc2c1)C(=O)c1ccccc1 Show InChI InChI=1S/C27H24FNO4S/c28-13-4-14-29-16-22(17-29)32-20-8-10-21(11-9-20)33-26-23-12-7-19(30)15-24(23)34-27(26)25(31)18-5-2-1-3-6-18/h1-3,5-12,15,22,30H,4,13-14,16-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Antagonist activity at ERalpha in human MCF7:WS8 cells incubated for 18 hrs by dual luciferase reporter gene assay relative to control				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50514280 (CHEMBL4586663) Show SMILES Oc1ccc2c(Oc3ccc(OC4CN(CCCF)C4)cc3)c(sc2c1)C(=O)c1ccccc1 Show InChI InChI=1S/C27H24FNO4S/c28-13-4-14-29-16-22(17-29)32-20-8-10-21(11-9-20)33-26-23-12-7-19(30)15-24(23)34-27(26)25(31)18-5-2-1-3-6-18/h1-3,5-12,15,22,30H,4,13-14,16-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.708	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assay				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50514287 (CHEMBL4532671) Show SMILES Cc1ccccc1C(=O)c1sc2cc(O)ccc2c1Oc1ccc(OCCN2CC(CF)C2)cc1 Show InChI InChI=1S/C28H26FNO4S/c1-18-4-2-3-5-23(18)26(32)28-27(24-11-6-20(31)14-25(24)35-28)34-22-9-7-21(8-10-22)33-13-12-30-16-19(15-29)17-30/h2-11,14,19,31H,12-13,15-17H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.955	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assay				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50514293 (CHEMBL4515212) Show SMILES Oc1ccc2c(Oc3ccc(OCCN4CC(CF)C4)cc3)c(sc2c1)C(=O)c1ccccc1 Show InChI InChI=1S/C27H24FNO4S/c28-15-18-16-29(17-18)12-13-32-21-7-9-22(10-8-21)33-26-23-11-6-20(30)14-24(23)34-27(26)25(31)19-4-2-1-3-5-19/h1-11,14,18,30H,12-13,15-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assay				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50514292 (CHEMBL4533964) Show SMILES Cc1cc(F)cc(C)c1C(=O)c1sc2cc(O)ccc2c1Oc1ccc(OC2CN(CCCF)C2)cc1 Show InChI InChI=1S/C29H27F2NO4S/c1-17-12-19(31)13-18(2)26(17)27(34)29-28(24-9-4-20(33)14-25(24)37-29)36-22-7-5-21(6-8-22)35-23-15-32(16-23)11-3-10-30/h4-9,12-14,23,33H,3,10-11,15-16H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assay				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50514283 (CHEMBL4524872) Show SMILES Oc1ccc2c(Oc3ccc(OCCN4CC(CF)C4)cc3)c(sc2c1)C(=O)c1ccc(F)cc1 Show InChI InChI=1S/C27H23F2NO4S/c28-14-17-15-30(16-17)11-12-33-21-6-8-22(9-7-21)34-26-23-10-5-20(31)13-24(23)35-27(26)25(32)18-1-3-19(29)4-2-18/h1-10,13,17,31H,11-12,14-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assay				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50514282 (CHEMBL4543096) Show SMILES Cc1cc(F)cc(C)c1C(=O)c1sc2cc(O)ccc2c1Oc1ccc(OCCN2CC(CF)C2)cc1 Show InChI InChI=1S/C29H27F2NO4S/c1-17-11-20(31)12-18(2)26(17)27(34)29-28(24-8-3-21(33)13-25(24)37-29)36-23-6-4-22(5-7-23)35-10-9-32-15-19(14-30)16-32/h3-8,11-13,19,33H,9-10,14-16H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assay				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50514284 (CHEMBL4483006) Show SMILES Cc1ccc(C(=O)c2sc3cc(O)ccc3c2Oc2ccc(OCCN3CC(CF)C3)cc2)c(C)c1 Show InChI InChI=1S/C29H28FNO4S/c1-18-3-9-24(19(2)13-18)27(33)29-28(25-10-4-21(32)14-26(25)36-29)35-23-7-5-22(6-8-23)34-12-11-31-16-20(15-30)17-31/h3-10,13-14,20,32H,11-12,15-17H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assay				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50514287 (CHEMBL4532671) Show SMILES Cc1ccccc1C(=O)c1sc2cc(O)ccc2c1Oc1ccc(OCCN2CC(CF)C2)cc1 Show InChI InChI=1S/C28H26FNO4S/c1-18-4-2-3-5-23(18)26(32)28-27(24-11-6-20(31)14-25(24)35-28)34-22-9-7-21(8-10-22)33-13-12-30-16-19(15-29)17-30/h2-11,14,19,31H,12-13,15-17H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Antagonist activity at ERalpha in human MCF7:WS8 cells incubated for 18 hrs by dual luciferase reporter gene assay relative to control				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50238741 (CHEBI:31638 | Faslodex | Fulvestrant | ICI-182780 ...) Show SMILES [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]1([H])c3ccc(O)cc3C[C@@H](CCCCCCCCC[S+]([O-])CCCC(F)(F)C(F)(F)F)[C@@]21[H] Show InChI InChI=1S/C32H47F5O3S/c1-30-17-15-26-25-12-11-24(38)21-23(25)20-22(29(26)27(30)13-14-28(30)39)10-7-5-3-2-4-6-8-18-41(40)19-9-16-31(33,34)32(35,36)37/h11-12,21-22,26-29,38-39H,2-10,13-20H2,1H3/t22-,26-,27+,28+,29-,30+,41?/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assay				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50514281 (CHEMBL4516021) Show SMILES Cc1ccccc1C(=O)c1sc2cc(O)ccc2c1Oc1ccc(OCCN2CCC2)cc1 Show InChI InChI=1S/C27H25NO4S/c1-18-5-2-3-6-22(18)25(30)27-26(23-12-7-19(29)17-24(23)33-27)32-21-10-8-20(9-11-21)31-16-15-28-13-4-14-28/h2-3,5-12,17,29H,4,13-16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assay				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50514279 (CHEMBL4527655) Show SMILES CC1CN(CCOc2ccc(Oc3c(sc4cc(O)ccc34)C(=O)c3ccccc3C)cc2)C1 Show InChI InChI=1S/C28H27NO4S/c1-18-16-29(17-18)13-14-32-21-8-10-22(11-9-21)33-27-24-12-7-20(30)15-25(24)34-28(27)26(31)23-6-4-3-5-19(23)2/h3-12,15,18,30H,13-14,16-17H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Antagonist activity at ERalpha in human MCF7:WS8 cells incubated for 18 hrs by dual luciferase reporter gene assay relative to control				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50514286 (CHEMBL4448178) Show SMILES Cc1ccccc1C(=O)c1sc2cc(O)ccc2c1Oc1ccc(OC2CN(CCCF)C2)cc1 Show InChI InChI=1S/C28H26FNO4S/c1-18-5-2-3-6-23(18)26(32)28-27(24-12-7-19(31)15-25(24)35-28)34-21-10-8-20(9-11-21)33-22-16-30(17-22)14-4-13-29/h2-3,5-12,15,22,31H,4,13-14,16-17H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Antagonist activity at ERalpha in human MCF7:WS8 cells incubated for 18 hrs by dual luciferase reporter gene assay relative to control				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50514286 (CHEMBL4448178) Show SMILES Cc1ccccc1C(=O)c1sc2cc(O)ccc2c1Oc1ccc(OC2CN(CCCF)C2)cc1 Show InChI InChI=1S/C28H26FNO4S/c1-18-5-2-3-6-23(18)26(32)28-27(24-12-7-19(31)15-25(24)35-28)34-21-10-8-20(9-11-21)33-22-16-30(17-22)14-4-13-29/h2-3,5-12,15,22,31H,4,13-14,16-17H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assay				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50514290 (CHEMBL4578883) Show SMILES Cc1cc(F)ccc1C(=O)c1sc2cc(O)ccc2c1Oc1ccc(OCCN2CC(CF)C2)cc1 Show InChI InChI=1S/C28H25F2NO4S/c1-17-12-19(30)2-8-23(17)26(33)28-27(24-9-3-20(32)13-25(24)36-28)35-22-6-4-21(5-7-22)34-11-10-31-15-18(14-29)16-31/h2-9,12-13,18,32H,10-11,14-16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Antagonist activity at ERalpha in human MCF7:WS8 cells incubated for 18 hrs by dual luciferase reporter gene assay relative to control				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50514285 (CHEMBL4436707) Show SMILES Cc1cc(F)cc(C)c1C(=O)c1sc2cc(O)ccc2c1Oc1ccc(OCCN2CC[C@H](CF)C2)cc1 |r| Show InChI InChI=1S/C30H29F2NO4S/c1-18-13-21(32)14-19(2)27(18)28(35)30-29(25-8-3-22(34)15-26(25)38-30)37-24-6-4-23(5-7-24)36-12-11-33-10-9-20(16-31)17-33/h3-8,13-15,20,34H,9-12,16-17H2,1-2H3/t20-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assay				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50514292 (CHEMBL4533964) Show SMILES Cc1cc(F)cc(C)c1C(=O)c1sc2cc(O)ccc2c1Oc1ccc(OC2CN(CCCF)C2)cc1 Show InChI InChI=1S/C29H27F2NO4S/c1-17-12-19(31)13-18(2)26(17)27(34)29-28(24-9-4-20(33)14-25(24)37-29)36-22-7-5-21(6-8-22)35-23-15-32(16-23)11-3-10-30/h4-9,12-14,23,33H,3,10-11,15-16H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Antagonist activity at ERalpha in human MCF7:WS8 cells incubated for 18 hrs by dual luciferase reporter gene assay relative to control				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50514282 (CHEMBL4543096) Show SMILES Cc1cc(F)cc(C)c1C(=O)c1sc2cc(O)ccc2c1Oc1ccc(OCCN2CC(CF)C2)cc1 Show InChI InChI=1S/C29H27F2NO4S/c1-17-11-20(31)12-18(2)26(17)27(34)29-28(24-8-3-21(33)13-25(24)37-29)36-23-6-4-22(5-7-23)35-10-9-32-15-19(14-30)16-32/h3-8,11-13,19,33H,9-10,14-16H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Antagonist activity at ERalpha in human MCF7:WS8 cells incubated for 18 hrs by dual luciferase reporter gene assay relative to control				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50514290 (CHEMBL4578883) Show SMILES Cc1cc(F)ccc1C(=O)c1sc2cc(O)ccc2c1Oc1ccc(OCCN2CC(CF)C2)cc1 Show InChI InChI=1S/C28H25F2NO4S/c1-17-12-19(30)2-8-23(17)26(33)28-27(24-9-3-20(32)13-25(24)36-28)35-22-6-4-21(5-7-22)34-11-10-31-15-18(14-29)16-31/h2-9,12-13,18,32H,10-11,14-16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assay				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50514293 (CHEMBL4515212) Show SMILES Oc1ccc2c(Oc3ccc(OCCN4CC(CF)C4)cc3)c(sc2c1)C(=O)c1ccccc1 Show InChI InChI=1S/C27H24FNO4S/c28-15-18-16-29(17-18)12-13-32-21-7-9-22(10-8-21)33-26-23-11-6-20(30)14-24(23)34-27(26)25(31)19-4-2-1-3-5-19/h1-11,14,18,30H,12-13,15-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Antagonist activity at ERalpha in human MCF7:WS8 cells incubated for 18 hrs by dual luciferase reporter gene assay relative to control				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50514294 (CHEMBL4564385) Show SMILES Cc1cc(O)ccc1C(=O)c1sc2cc(O)ccc2c1Oc1ccc(OCCN2CC(CF)C2)cc1 Show InChI InChI=1S/C28H26FNO5S/c1-17-12-19(31)2-8-23(17)26(33)28-27(24-9-3-20(32)13-25(24)36-28)35-22-6-4-21(5-7-22)34-11-10-30-15-18(14-29)16-30/h2-9,12-13,18,31-32H,10-11,14-16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assay				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50514289 (CHEMBL4538085) Show SMILES Cc1cc(F)ccc1C(=O)c1sc2cc(O)ccc2c1Oc1ccc(OC2CN(CCCF)C2)cc1 Show InChI InChI=1S/C28H25F2NO4S/c1-17-13-18(30)3-9-23(17)26(33)28-27(24-10-4-19(32)14-25(24)36-28)35-21-7-5-20(6-8-21)34-22-15-31(16-22)12-2-11-29/h3-10,13-14,22,32H,2,11-12,15-16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Antagonist activity at ERalpha in human MCF7:WS8 cells incubated for 18 hrs by dual luciferase reporter gene assay relative to control				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50514295 (CHEMBL4440649) Show SMILES Cc1cc(F)cc(C)c1C(=O)c1sc2cc(O)ccc2c1Oc1ccc(OCCN2CC[C@@H](CF)C2)cc1 |r| Show InChI InChI=1S/C30H29F2NO4S/c1-18-13-21(32)14-19(2)27(18)28(35)30-29(25-8-3-22(34)15-26(25)38-30)37-24-6-4-23(5-7-24)36-12-11-33-10-9-20(16-31)17-33/h3-8,13-15,20,34H,9-12,16-17H2,1-2H3/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assay				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50514278 (CHEMBL4436415) Show SMILES Cc1cc(F)cc(C)c1C(=O)c1sc2cc(O)ccc2c1Oc1ccc(OC2CN(C2)C2CC2)cc1 Show InChI InChI=1S/C29H26FNO4S/c1-16-11-18(30)12-17(2)26(16)27(33)29-28(24-10-5-20(32)13-25(24)36-29)35-22-8-6-21(7-9-22)34-23-14-31(15-23)19-3-4-19/h5-13,19,23,32H,3-4,14-15H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assay				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50514284 (CHEMBL4483006) Show SMILES Cc1ccc(C(=O)c2sc3cc(O)ccc3c2Oc2ccc(OCCN3CC(CF)C3)cc2)c(C)c1 Show InChI InChI=1S/C29H28FNO4S/c1-18-3-9-24(19(2)13-18)27(33)29-28(25-10-4-21(32)14-26(25)36-29)35-23-7-5-22(6-8-23)34-12-11-31-16-20(15-30)17-31/h3-10,13-14,20,32H,11-12,15-17H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.40	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Antagonist activity at ERalpha in human MCF7:WS8 cells incubated for 18 hrs by dual luciferase reporter gene assay relative to control				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50514288 (CHEMBL4464171) Show SMILES Oc1ccc(cc1)C(=O)c1sc2cc(O)ccc2c1Oc1ccc(OCCN2CC(CF)C2)cc1 Show InChI InChI=1S/C27H24FNO5S/c28-14-17-15-29(16-17)11-12-33-21-6-8-22(9-7-21)34-26-23-10-5-20(31)13-24(23)35-27(26)25(32)18-1-3-19(30)4-2-18/h1-10,13,17,30-31H,11-12,14-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.10	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assay				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50514289 (CHEMBL4538085) Show SMILES Cc1cc(F)ccc1C(=O)c1sc2cc(O)ccc2c1Oc1ccc(OC2CN(CCCF)C2)cc1 Show InChI InChI=1S/C28H25F2NO4S/c1-17-13-18(30)3-9-23(17)26(33)28-27(24-10-4-19(32)14-25(24)36-28)35-21-7-5-20(6-8-21)34-22-15-31(16-22)12-2-11-29/h3-10,13-14,22,32H,2,11-12,15-16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assay				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50514291 (CHEMBL4447374) Show SMILES Cc1ccccc1C(=O)c1sc2cc(O)ccc2c1Oc1ccc(OCCN2CC[C@@H](CF)C2)cc1 |r| Show InChI InChI=1S/C29H28FNO4S/c1-19-4-2-3-5-24(19)27(33)29-28(25-11-6-21(32)16-26(25)36-29)35-23-9-7-22(8-10-23)34-15-14-31-13-12-20(17-30)18-31/h2-11,16,20,32H,12-15,17-18H2,1H3/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assay				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50514278 (CHEMBL4436415) Show SMILES Cc1cc(F)cc(C)c1C(=O)c1sc2cc(O)ccc2c1Oc1ccc(OC2CN(C2)C2CC2)cc1 Show InChI InChI=1S/C29H26FNO4S/c1-16-11-18(30)12-17(2)26(16)27(33)29-28(24-10-5-20(32)13-25(24)36-29)35-22-8-6-21(7-9-22)34-23-14-31(15-23)19-3-4-19/h5-13,19,23,32H,3-4,14-15H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Antagonist activity at ERalpha in human MCF7:WS8 cells incubated for 18 hrs by dual luciferase reporter gene assay relative to control				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50514295 (CHEMBL4440649) Show SMILES Cc1cc(F)cc(C)c1C(=O)c1sc2cc(O)ccc2c1Oc1ccc(OCCN2CC[C@@H](CF)C2)cc1 |r| Show InChI InChI=1S/C30H29F2NO4S/c1-18-13-21(32)14-19(2)27(18)28(35)30-29(25-8-3-22(34)15-26(25)38-30)37-24-6-4-23(5-7-24)36-12-11-33-10-9-20(16-31)17-33/h3-8,13-15,20,34H,9-12,16-17H2,1-2H3/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Antagonist activity at ERalpha in human MCF7:WS8 cells incubated for 18 hrs by dual luciferase reporter gene assay relative to control				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50514294 (CHEMBL4564385) Show SMILES Cc1cc(O)ccc1C(=O)c1sc2cc(O)ccc2c1Oc1ccc(OCCN2CC(CF)C2)cc1 Show InChI InChI=1S/C28H26FNO5S/c1-17-12-19(31)2-8-23(17)26(33)28-27(24-9-3-20(32)13-25(24)36-28)35-22-6-4-21(5-7-22)34-11-10-30-15-18(14-29)16-30/h2-9,12-13,18,31-32H,10-11,14-16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Antagonist activity at ERalpha in human MCF7:WS8 cells incubated for 18 hrs by dual luciferase reporter gene assay relative to control				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50514283 (CHEMBL4524872) Show SMILES Oc1ccc2c(Oc3ccc(OCCN4CC(CF)C4)cc3)c(sc2c1)C(=O)c1ccc(F)cc1 Show InChI InChI=1S/C27H23F2NO4S/c28-14-17-15-30(16-17)11-12-33-21-6-8-22(9-7-21)34-26-23-10-5-20(31)13-24(23)35-27(26)25(32)18-1-3-19(29)4-2-18/h1-10,13,17,31H,11-12,14-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Antagonist activity at ERalpha in human MCF7:WS8 cells incubated for 18 hrs by dual luciferase reporter gene assay relative to control				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50514288 (CHEMBL4464171) Show SMILES Oc1ccc(cc1)C(=O)c1sc2cc(O)ccc2c1Oc1ccc(OCCN2CC(CF)C2)cc1 Show InChI InChI=1S/C27H24FNO5S/c28-14-17-15-29(16-17)11-12-33-21-6-8-22(9-7-21)34-26-23-10-5-20(31)13-24(23)35-27(26)25(32)18-1-3-19(30)4-2-18/h1-10,13,17,30-31H,11-12,14-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Antagonist activity at ERalpha in human MCF7:WS8 cells incubated for 18 hrs by dual luciferase reporter gene assay relative to control				J Med Chem 62: 11301-11323 (2019) Article DOI: 10.1021/acs.jmedchem.9b01580 BindingDB Entry DOI: 10.7270/Q2K64NDQ
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase zeta (Homo sapiens)	BDBM50464775 (CHEMBL4278170) Show SMILES FC(F)(F)Sc1ccc(CNCc2ccc(SC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C16H13F6NS2/c17-15(18,19)24-13-5-1-11(2-6-13)9-23-10-12-3-7-14(8-4-12)25-16(20,21)22/h1-8,23H,9-10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Universidad San Pablo-CEU Curated by ChEMBL					Assay Description Inhibition of human recombinant PTPRZ1 using pNPP as substrate by fluorescence spectrometric analysis				Eur J Med Chem 144: 318-329 (2018) Article DOI: 10.1016/j.ejmech.2017.11.080 BindingDB Entry DOI: 10.7270/Q2C53PHW
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase zeta (Homo sapiens)	BDBM50464778 (CHEMBL4285054) Show SMILES FC(F)(F)Sc1ccc(COc2ccc(SC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C15H10F6OS2/c16-14(17,18)23-12-5-1-10(2-6-12)9-22-11-3-7-13(8-4-11)24-15(19,20)21/h1-8H,9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Universidad San Pablo-CEU Curated by ChEMBL					Assay Description Inhibition of human recombinant PTPRZ1 using pNPP as substrate by fluorescence spectrometric analysis				Eur J Med Chem 144: 318-329 (2018) Article DOI: 10.1016/j.ejmech.2017.11.080 BindingDB Entry DOI: 10.7270/Q2C53PHW
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50464775 (CHEMBL4278170) Show SMILES FC(F)(F)Sc1ccc(CNCc2ccc(SC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C16H13F6NS2/c17-15(18,19)24-13-5-1-11(2-6-13)9-23-10-12-3-7-14(8-4-12)25-16(20,21)22/h1-8,23H,9-10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Universidad San Pablo-CEU Curated by ChEMBL					Assay Description Inhibition of human recombinant PTP1B using pNPP as substrate by fluorescence spectrometric analysis				Eur J Med Chem 144: 318-329 (2018) Article DOI: 10.1016/j.ejmech.2017.11.080 BindingDB Entry DOI: 10.7270/Q2C53PHW
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase zeta (Homo sapiens)	BDBM50464773 (CHEMBL4286807) Show SMILES FC(F)(F)Sc1ccc(CNC(=O)Cc2ccc(SC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C17H13F6NOS2/c18-16(19,20)26-13-5-1-11(2-6-13)9-15(25)24-10-12-3-7-14(8-4-12)27-17(21,22)23/h1-8H,9-10H2,(H,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Universidad San Pablo-CEU Curated by ChEMBL					Assay Description Inhibition of human recombinant PTPRZ1 using pNPP as substrate by fluorescence spectrometric analysis				Eur J Med Chem 144: 318-329 (2018) Article DOI: 10.1016/j.ejmech.2017.11.080 BindingDB Entry DOI: 10.7270/Q2C53PHW
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50464772 (CHEMBL4293314) Show SMILES FC(F)(F)Sc1ccc(NCc2ccccc2)cc1 Show InChI InChI=1S/C14H12F3NS/c15-14(16,17)19-13-8-6-12(7-9-13)18-10-11-4-2-1-3-5-11/h1-9,18H,10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad San Pablo-CEU Curated by ChEMBL					Assay Description Inhibition of human recombinant PTP1B using pNPP as substrate by fluorescence spectrometric analysis				Eur J Med Chem 144: 318-329 (2018) Article DOI: 10.1016/j.ejmech.2017.11.080 BindingDB Entry DOI: 10.7270/Q2C53PHW
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase zeta (Homo sapiens)	BDBM50464777 (CHEMBL4286401) Show SMILES FC(F)(F)S(=O)(=O)c1ccc(COc2ccc(cc2)S(=O)(=O)C(F)(F)F)cc1 Show InChI InChI=1S/C15H10F6O5S2/c16-14(17,18)27(22,23)12-5-1-10(2-6-12)9-26-11-3-7-13(8-4-11)28(24,25)15(19,20)21/h1-8H,9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad San Pablo-CEU Curated by ChEMBL					Assay Description Inhibition of PTPRZ1 (unknown origin) using pNPP as substrate preincubated for 15 mins followed by substrate addition measured after 10 mins by spect...				Eur J Med Chem 144: 318-329 (2018) Article DOI: 10.1016/j.ejmech.2017.11.080 BindingDB Entry DOI: 10.7270/Q2C53PHW
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase zeta (Homo sapiens)	BDBM50464772 (CHEMBL4293314) Show SMILES FC(F)(F)Sc1ccc(NCc2ccccc2)cc1 Show InChI InChI=1S/C14H12F3NS/c15-14(16,17)19-13-8-6-12(7-9-13)18-10-11-4-2-1-3-5-11/h1-9,18H,10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad San Pablo-CEU Curated by ChEMBL					Assay Description Inhibition of human recombinant PTPRZ1 using pNPP as substrate by fluorescence spectrometric analysis				Eur J Med Chem 144: 318-329 (2018) Article DOI: 10.1016/j.ejmech.2017.11.080 BindingDB Entry DOI: 10.7270/Q2C53PHW
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase zeta (Homo sapiens)	BDBM50464774 (CHEMBL4285322) Show SMILES FC(F)(F)S(=O)(=O)c1ccc(CC(=O)Nc2ccc(cc2)S(=O)(=O)C(F)(F)F)cc1 Show InChI InChI=1S/C16H11F6NO5S2/c17-15(18,19)29(25,26)12-5-1-10(2-6-12)9-14(24)23-11-3-7-13(8-4-11)30(27,28)16(20,21)22/h1-8H,9H2,(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad San Pablo-CEU Curated by ChEMBL					Assay Description Inhibition of human recombinant PTPRZ1 using pNPP as substrate by fluorescence spectrometric analysis				Eur J Med Chem 144: 318-329 (2018) Article DOI: 10.1016/j.ejmech.2017.11.080 BindingDB Entry DOI: 10.7270/Q2C53PHW
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase zeta (Homo sapiens)	BDBM50464776 (CHEMBL4279566) Show SMILES FC(F)(F)Sc1ccc(CNC(=O)c2ccc(SC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C16H11F6NOS2/c17-15(18,19)25-12-5-1-10(2-6-12)9-23-14(24)11-3-7-13(8-4-11)26-16(20,21)22/h1-8H,9H2,(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universidad San Pablo-CEU Curated by ChEMBL					Assay Description Inhibition of human recombinant PTPRZ1 using pNPP as substrate by fluorescence spectrometric analysis				Eur J Med Chem 144: 318-329 (2018) Article DOI: 10.1016/j.ejmech.2017.11.080 BindingDB Entry DOI: 10.7270/Q2C53PHW
					More data for this Ligand-Target Pair