Found 110 hits with Last Name = 'li' and Initial = 'pk' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Melatonin receptor type 1A
(Homo sapiens (Human)) | BDBM29611
(2-Iodomelatonin | CHEMBL289233 | Melatonin,2-Iodo)Show InChI InChI=1S/C13H15IN2O2/c1-8(17)15-6-5-10-11-7-9(18-2)3-4-12(11)16-13(10)14/h3-4,7,16H,5-6H2,1-2H3,(H,15,17) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
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Similars
| PDB Article
| 0.0800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Displacement of 2-[125I]-Iodomelatonin from human Melatonin receptor type 1A expressed in CHO cells |
Bioorg Med Chem Lett 7: 2409-2414 (1997)
Article DOI: 10.1016/S0960-894X(97)00444-7 BindingDB Entry DOI: 10.7270/Q25T3KFF |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Melatonin receptor type 1A
(Homo sapiens (Human)) | BDBM9019
(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)Show InChI InChI=1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank Article PubMed
| 0.0800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Duquesne University
Curated by ChEMBL
| Assay Description Inhibition of the 2-[125I]- iodomelatonin binding to Melatonin receptor type 1A expressed in CHO cells |
J Med Chem 40: 4195-8 (1998)
Article DOI: 10.1021/jm970437q BindingDB Entry DOI: 10.7270/Q2930S90 |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1A
(Homo sapiens (Human)) | BDBM50035202
(CHEMBL291857 | N-[2-(2,7-Dimethoxy-naphthalen-1-yl...)Show InChI InChI=1S/C17H21NO3/c1-4-17(19)18-10-9-14-15-11-13(20-2)7-5-12(15)6-8-16(14)21-3/h5-8,11H,4,9-10H2,1-3H3,(H,18,19) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.0990 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Duquesne University
Curated by ChEMBL
| Assay Description Inhibition of the 2-[125I]- iodomelatonin binding to Melatonin receptor type 1A expressed in CHO cells |
J Med Chem 40: 4195-8 (1998)
Article DOI: 10.1021/jm970437q BindingDB Entry DOI: 10.7270/Q2930S90 |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1A
(Homo sapiens (Human)) | BDBM50035202
(CHEMBL291857 | N-[2-(2,7-Dimethoxy-naphthalen-1-yl...)Show InChI InChI=1S/C17H21NO3/c1-4-17(19)18-10-9-14-15-11-13(20-2)7-5-12(15)6-8-16(14)21-3/h5-8,11H,4,9-10H2,1-3H3,(H,18,19) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| 0.0990 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Displacement of 2-[125I]-Iodomelatonin from human Melatonin receptor type 1A expressed in CHO cells |
Bioorg Med Chem Lett 7: 2409-2414 (1997)
Article DOI: 10.1016/S0960-894X(97)00444-7 BindingDB Entry DOI: 10.7270/Q25T3KFF |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1B
(Homo sapiens (Human)) | BDBM9019
(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)Show InChI InChI=1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16) | PDB
Reactome pathway KEGG
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| DrugBank Article PubMed
| 0.120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Duquesne University
Curated by ChEMBL
| Assay Description Inhibition of the 2-[125I]- iodomelatonin binding to Melatonin receptor type 1B expressed in CHO cells |
J Med Chem 40: 4195-8 (1998)
Article DOI: 10.1021/jm970437q BindingDB Entry DOI: 10.7270/Q2930S90 |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1A
(Homo sapiens (Human)) | BDBM9019
(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)Show InChI InChI=1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16) | PDB
Reactome pathway KEGG
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank Article
| 0.130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Binding affinity of the compound against human Melatonin receptor type 1A by displacement of [125I]-iodomelatonin stably expressed in CHO cells |
Bioorg Med Chem Lett 7: 2177-2180 (1997)
Article DOI: 10.1016/S0960-894X(97)00392-2 BindingDB Entry DOI: 10.7270/Q208659R |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1B
(Homo sapiens (Human)) | BDBM29611
(2-Iodomelatonin | CHEMBL289233 | Melatonin,2-Iodo)Show InChI InChI=1S/C13H15IN2O2/c1-8(17)15-6-5-10-11-7-9(18-2)3-4-12(11)16-13(10)14/h3-4,7,16H,5-6H2,1-2H3,(H,15,17) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| Article
| 0.150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Compound was tested for binding affinity against human Melatonin receptor type 1B in CHO cells |
Bioorg Med Chem Lett 7: 2409-2414 (1997)
Article DOI: 10.1016/S0960-894X(97)00444-7 BindingDB Entry DOI: 10.7270/Q25T3KFF |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1A
(Homo sapiens (Human)) | BDBM9019
(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)Show InChI InChI=1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16) | PDB
Reactome pathway KEGG
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
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| DrugBank Article
| 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Displacement of 2-[125I]-Iodomelatonin from human Melatonin receptor type 1A expressed in CHO cells |
Bioorg Med Chem Lett 7: 2409-2414 (1997)
Article DOI: 10.1016/S0960-894X(97)00444-7 BindingDB Entry DOI: 10.7270/Q25T3KFF |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1B
(Homo sapiens (Human)) | BDBM9019
(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)Show InChI InChI=1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16) | PDB
Reactome pathway KEGG
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
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| DrugBank Article
| 0.230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Binding affinity of the compound against human Melatonin receptor type 1B by displacement of [125I]-iodomelatonin stably expressed in CHO cells |
Bioorg Med Chem Lett 7: 2177-2180 (1997)
Article DOI: 10.1016/S0960-894X(97)00392-2 BindingDB Entry DOI: 10.7270/Q208659R |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1B
(Homo sapiens (Human)) | BDBM9019
(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)Show InChI InChI=1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16) | PDB
Reactome pathway KEGG
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| DrugBank Article
| 0.290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of 2-[125I]-Iodomelatonin binding to human Melatonin receptor type 1B expressed in CHO cells |
Bioorg Med Chem Lett 7: 2409-2414 (1997)
Article DOI: 10.1016/S0960-894X(97)00444-7 BindingDB Entry DOI: 10.7270/Q25T3KFF |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1B
(Homo sapiens (Human)) | BDBM50035202
(CHEMBL291857 | N-[2-(2,7-Dimethoxy-naphthalen-1-yl...)Show InChI InChI=1S/C17H21NO3/c1-4-17(19)18-10-9-14-15-11-13(20-2)7-5-12(15)6-8-16(14)21-3/h5-8,11H,4,9-10H2,1-3H3,(H,18,19) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.380 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Duquesne University
Curated by ChEMBL
| Assay Description Inhibition of the 2-[125I]- iodomelatonin binding to Melatonin receptor type 1B expressed in CHO cells |
J Med Chem 40: 4195-8 (1998)
Article DOI: 10.1021/jm970437q BindingDB Entry DOI: 10.7270/Q2930S90 |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1B
(Homo sapiens (Human)) | BDBM50035202
(CHEMBL291857 | N-[2-(2,7-Dimethoxy-naphthalen-1-yl...)Show InChI InChI=1S/C17H21NO3/c1-4-17(19)18-10-9-14-15-11-13(20-2)7-5-12(15)6-8-16(14)21-3/h5-8,11H,4,9-10H2,1-3H3,(H,18,19) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| 0.380 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of 2-[125I]-Iodomelatonin binding to human Melatonin receptor type 1B expressed in CHO cells |
Bioorg Med Chem Lett 7: 2409-2414 (1997)
Article DOI: 10.1016/S0960-894X(97)00444-7 BindingDB Entry DOI: 10.7270/Q25T3KFF |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1A
(Homo sapiens (Human)) | BDBM50290238
(CHEMBL80736 | N-[2-(2-Ethoxy-7-methoxy-naphthalen-...)Show InChI InChI=1S/C18H23NO3/c1-4-18(20)19-11-10-15-16-12-14(21-3)8-6-13(16)7-9-17(15)22-5-2/h6-9,12H,4-5,10-11H2,1-3H3,(H,19,20) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| 0.390 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Displacement of 2-[125I]-Iodomelatonin from human Melatonin receptor type 1A expressed in CHO cells |
Bioorg Med Chem Lett 7: 2409-2414 (1997)
Article DOI: 10.1016/S0960-894X(97)00444-7 BindingDB Entry DOI: 10.7270/Q25T3KFF |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1B
(Homo sapiens (Human)) | BDBM50290000
(CHEMBL68864 | N-[2-(6-Methoxy-quinolin-4-yl)-ethyl...)Show InChI InChI=1S/C16H20N2O2/c1-3-4-16(19)18-10-8-12-7-9-17-15-6-5-13(20-2)11-14(12)15/h5-7,9,11H,3-4,8,10H2,1-2H3,(H,18,19) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| 0.410 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Binding affinity of the compound against human Melatonin receptor type 1B by displacement of [125I]-iodomelatonin stably expressed in CHO cells |
Bioorg Med Chem Lett 7: 2177-2180 (1997)
Article DOI: 10.1016/S0960-894X(97)00392-2 BindingDB Entry DOI: 10.7270/Q208659R |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1B
(Homo sapiens (Human)) | BDBM50290003
(CHEMBL306468 | N-[2-(6-Methoxy-quinolin-4-yl)-ethy...)Show InChI InChI=1S/C15H18N2O2/c1-3-15(18)17-9-7-11-6-8-16-14-5-4-12(19-2)10-13(11)14/h4-6,8,10H,3,7,9H2,1-2H3,(H,17,18) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| 0.960 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Binding affinity of the compound against human Melatonin receptor type 1B by displacement of [125I]-iodomelatonin stably expressed in CHO cells |
Bioorg Med Chem Lett 7: 2177-2180 (1997)
Article DOI: 10.1016/S0960-894X(97)00392-2 BindingDB Entry DOI: 10.7270/Q208659R |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1B
(Homo sapiens (Human)) | BDBM50290238
(CHEMBL80736 | N-[2-(2-Ethoxy-7-methoxy-naphthalen-...)Show InChI InChI=1S/C18H23NO3/c1-4-18(20)19-11-10-15-16-12-14(21-3)8-6-13(16)7-9-17(15)22-5-2/h6-9,12H,4-5,10-11H2,1-3H3,(H,19,20) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of 2-[125I]-Iodomelatonin binding to human Melatonin receptor type 1B expressed in CHO cells |
Bioorg Med Chem Lett 7: 2409-2414 (1997)
Article DOI: 10.1016/S0960-894X(97)00444-7 BindingDB Entry DOI: 10.7270/Q25T3KFF |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1B
(Homo sapiens (Human)) | BDBM50290234
(CHEMBL440692 | N-[2-(2-Hydroxy-7-methoxy-naphthale...)Show InChI InChI=1S/C16H19NO3/c1-3-16(19)17-9-8-13-14-10-12(20-2)6-4-11(14)5-7-15(13)18/h4-7,10,18H,3,8-9H2,1-2H3,(H,17,19) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| CHEMBL PC cid PC sid UniChem
Similars
| Article
| 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of 2-[125I]-Iodomelatonin binding to human Melatonin receptor type 1B expressed in CHO cells |
Bioorg Med Chem Lett 7: 2409-2414 (1997)
Article DOI: 10.1016/S0960-894X(97)00444-7 BindingDB Entry DOI: 10.7270/Q25T3KFF |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1A
(Homo sapiens (Human)) | BDBM50061570
(Bromo-acetic acid 7-methoxy-1-(2-propionylamino-et...)Show InChI InChI=1S/C18H20BrNO4/c1-3-17(21)20-9-8-14-15-10-13(23-2)6-4-12(15)5-7-16(14)24-18(22)11-19/h4-7,10H,3,8-9,11H2,1-2H3,(H,20,21) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Duquesne University
Curated by ChEMBL
| Assay Description Inhibition of the 2-[125I]- iodomelatonin binding to Melatonin receptor type 1A expressed in CHO cells |
J Med Chem 40: 4195-8 (1998)
Article DOI: 10.1021/jm970437q BindingDB Entry DOI: 10.7270/Q2930S90 |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1B
(Homo sapiens (Human)) | BDBM50290239
(CHEMBL78751 | N-{2-[2-(2-Hydroxy-ethoxy)-7-methoxy...)Show InChI InChI=1S/C18H23NO4/c1-3-18(21)19-9-8-15-16-12-14(22-2)6-4-13(16)5-7-17(15)23-11-10-20/h4-7,12,20H,3,8-11H2,1-2H3,(H,19,21) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of 2-[125I]-Iodomelatonin binding to human Melatonin receptor type 1B expressed in CHO cells |
Bioorg Med Chem Lett 7: 2409-2414 (1997)
Article DOI: 10.1016/S0960-894X(97)00444-7 BindingDB Entry DOI: 10.7270/Q25T3KFF |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1B
(Homo sapiens (Human)) | BDBM50290002
(CHEMBL69521 | N-[2-(6-Methoxy-quinolin-4-yl)-ethyl...)Show InChI InChI=1S/C14H16N2O2/c1-10(17)15-7-5-11-6-8-16-14-4-3-12(18-2)9-13(11)14/h3-4,6,8-9H,5,7H2,1-2H3,(H,15,17) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Binding affinity of the compound against human Melatonin receptor type 1B by displacement of [125I]-iodomelatonin stably expressed in CHO cells |
Bioorg Med Chem Lett 7: 2177-2180 (1997)
Article DOI: 10.1016/S0960-894X(97)00392-2 BindingDB Entry DOI: 10.7270/Q208659R |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1B
(Homo sapiens (Human)) | BDBM50061569
(CHEMBL131919 | Chloro-acetic acid 7-methoxy-1-(2-p...)Show InChI InChI=1S/C18H20ClNO4/c1-3-17(21)20-9-8-14-15-10-13(23-2)6-4-12(15)5-7-16(14)24-18(22)11-19/h4-7,10H,3,8-9,11H2,1-2H3,(H,20,21) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Duquesne University
Curated by ChEMBL
| Assay Description Inhibition of the 2-[125I]- iodomelatonin binding to Melatonin receptor type 1B expressed in CHO cells |
J Med Chem 40: 4195-8 (1998)
Article DOI: 10.1021/jm970437q BindingDB Entry DOI: 10.7270/Q2930S90 |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1A
(Homo sapiens (Human)) | BDBM50290234
(CHEMBL440692 | N-[2-(2-Hydroxy-7-methoxy-naphthale...)Show InChI InChI=1S/C16H19NO3/c1-3-16(19)17-9-8-13-14-10-12(20-2)6-4-11(14)5-7-15(13)18/h4-7,10,18H,3,8-9H2,1-2H3,(H,17,19) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Displacement of 2-[125I]-Iodomelatonin from human Melatonin receptor type 1A expressed in CHO cells |
Bioorg Med Chem Lett 7: 2409-2414 (1997)
Article DOI: 10.1016/S0960-894X(97)00444-7 BindingDB Entry DOI: 10.7270/Q25T3KFF |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1A
(Homo sapiens (Human)) | BDBM50290000
(CHEMBL68864 | N-[2-(6-Methoxy-quinolin-4-yl)-ethyl...)Show InChI InChI=1S/C16H20N2O2/c1-3-4-16(19)18-10-8-12-7-9-17-15-6-5-13(20-2)11-14(12)15/h5-7,9,11H,3-4,8,10H2,1-2H3,(H,18,19) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Binding affinity of the compound against human Melatonin receptor type 1A by displacement of [125I]-iodomelatonin stably expressed in CHO cells |
Bioorg Med Chem Lett 7: 2177-2180 (1997)
Article DOI: 10.1016/S0960-894X(97)00392-2 BindingDB Entry DOI: 10.7270/Q208659R |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1A
(Homo sapiens (Human)) | BDBM50290239
(CHEMBL78751 | N-{2-[2-(2-Hydroxy-ethoxy)-7-methoxy...)Show InChI InChI=1S/C18H23NO4/c1-3-18(21)19-9-8-15-16-12-14(22-2)6-4-13(16)5-7-17(15)23-11-10-20/h4-7,12,20H,3,8-11H2,1-2H3,(H,19,21) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| 4.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Displacement of 2-[125I]-Iodomelatonin from human Melatonin receptor type 1A expressed in CHO cells |
Bioorg Med Chem Lett 7: 2409-2414 (1997)
Article DOI: 10.1016/S0960-894X(97)00444-7 BindingDB Entry DOI: 10.7270/Q25T3KFF |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1A
(Homo sapiens (Human)) | BDBM50290002
(CHEMBL69521 | N-[2-(6-Methoxy-quinolin-4-yl)-ethyl...)Show InChI InChI=1S/C14H16N2O2/c1-10(17)15-7-5-11-6-8-16-14-4-3-12(18-2)9-13(11)14/h3-4,6,8-9H,5,7H2,1-2H3,(H,15,17) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| 5.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Binding affinity of the compound against human Melatonin receptor type 1A by displacement of [125I]-iodomelatonin stably expressed in CHO cells |
Bioorg Med Chem Lett 7: 2177-2180 (1997)
Article DOI: 10.1016/S0960-894X(97)00392-2 BindingDB Entry DOI: 10.7270/Q208659R |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1B
(Homo sapiens (Human)) | BDBM50290237
(CHEMBL82135 | N-[2-(2-Butoxy-7-methoxy-naphthalen-...)Show InChI InChI=1S/C20H27NO3/c1-4-6-13-24-19-10-8-15-7-9-16(23-3)14-18(15)17(19)11-12-21-20(22)5-2/h7-10,14H,4-6,11-13H2,1-3H3,(H,21,22) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| 6.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of 2-[125I]-Iodomelatonin binding to human Melatonin receptor type 1B expressed in CHO cells |
Bioorg Med Chem Lett 7: 2409-2414 (1997)
Article DOI: 10.1016/S0960-894X(97)00444-7 BindingDB Entry DOI: 10.7270/Q25T3KFF |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1A
(Homo sapiens (Human)) | BDBM50290003
(CHEMBL306468 | N-[2-(6-Methoxy-quinolin-4-yl)-ethy...)Show InChI InChI=1S/C15H18N2O2/c1-3-15(18)17-9-7-11-6-8-16-14-5-4-12(19-2)10-13(11)14/h4-6,8,10H,3,7,9H2,1-2H3,(H,17,18) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| 6.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Binding affinity of the compound against human Melatonin receptor type 1A by displacement of [125I]-iodomelatonin stably expressed in CHO cells |
Bioorg Med Chem Lett 7: 2177-2180 (1997)
Article DOI: 10.1016/S0960-894X(97)00392-2 BindingDB Entry DOI: 10.7270/Q208659R |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1A
(Homo sapiens (Human)) | BDBM50290237
(CHEMBL82135 | N-[2-(2-Butoxy-7-methoxy-naphthalen-...)Show InChI InChI=1S/C20H27NO3/c1-4-6-13-24-19-10-8-15-7-9-16(23-3)14-18(15)17(19)11-12-21-20(22)5-2/h7-10,14H,4-6,11-13H2,1-3H3,(H,21,22) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| 7.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Displacement of 2-[125I]-Iodomelatonin from human Melatonin receptor type 1A expressed in CHO cells |
Bioorg Med Chem Lett 7: 2409-2414 (1997)
Article DOI: 10.1016/S0960-894X(97)00444-7 BindingDB Entry DOI: 10.7270/Q25T3KFF |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1A
(Homo sapiens (Human)) | BDBM50290241
(CHEMBL311106 | N-[2-(7-Methoxy-2-propoxy-naphthale...)Show InChI InChI=1S/C19H25NO3/c1-4-12-23-18-9-7-14-6-8-15(22-3)13-17(14)16(18)10-11-20-19(21)5-2/h6-9,13H,4-5,10-12H2,1-3H3,(H,20,21) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| 8.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Displacement of 2-[125I]-Iodomelatonin from human Melatonin receptor type 1A expressed in CHO cells |
Bioorg Med Chem Lett 7: 2409-2414 (1997)
Article DOI: 10.1016/S0960-894X(97)00444-7 BindingDB Entry DOI: 10.7270/Q25T3KFF |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1B
(Homo sapiens (Human)) | BDBM50290236
(CHEMBL80792 | N-{2-[2-(2-Dimethylamino-ethoxy)-7-m...)Show InChI InChI=1S/C20H28N2O3/c1-5-20(23)21-11-10-17-18-14-16(24-4)8-6-15(18)7-9-19(17)25-13-12-22(2)3/h6-9,14H,5,10-13H2,1-4H3,(H,21,23) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of 2-[125I]-Iodomelatonin binding to human Melatonin receptor type 1B expressed in CHO cells |
Bioorg Med Chem Lett 7: 2409-2414 (1997)
Article DOI: 10.1016/S0960-894X(97)00444-7 BindingDB Entry DOI: 10.7270/Q25T3KFF |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1A
(Homo sapiens (Human)) | BDBM50061569
(CHEMBL131919 | Chloro-acetic acid 7-methoxy-1-(2-p...)Show InChI InChI=1S/C18H20ClNO4/c1-3-17(21)20-9-8-14-15-10-13(23-2)6-4-12(15)5-7-16(14)24-18(22)11-19/h4-7,10H,3,8-9,11H2,1-2H3,(H,20,21) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Duquesne University
Curated by ChEMBL
| Assay Description Inhibition of the 2-[125I]- iodomelatonin binding to Melatonin receptor type 1A expressed in CHO cells |
J Med Chem 40: 4195-8 (1998)
Article DOI: 10.1021/jm970437q BindingDB Entry DOI: 10.7270/Q2930S90 |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1B
(Homo sapiens (Human)) | BDBM50290241
(CHEMBL311106 | N-[2-(7-Methoxy-2-propoxy-naphthale...)Show InChI InChI=1S/C19H25NO3/c1-4-12-23-18-9-7-14-6-8-15(22-3)13-17(14)16(18)10-11-20-19(21)5-2/h6-9,13H,4-5,10-12H2,1-3H3,(H,20,21) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of 2-[125I]-Iodomelatonin binding to human Melatonin receptor type 1B expressed in CHO cells |
Bioorg Med Chem Lett 7: 2409-2414 (1997)
Article DOI: 10.1016/S0960-894X(97)00444-7 BindingDB Entry DOI: 10.7270/Q25T3KFF |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1B
(Homo sapiens (Human)) | BDBM50290235
(CHEMBL78338 | {2-[7-Methoxy-1-(2-propionylamino-et...)Show SMILES CCC(=O)NCCc1c(OCC[N+](C)(C)C)ccc2ccc(OC)cc12 Show InChI InChI=1S/C21H30N2O3/c1-6-21(24)22-12-11-18-19-15-17(25-5)9-7-16(19)8-10-20(18)26-14-13-23(2,3)4/h7-10,15H,6,11-14H2,1-5H3/p+1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of 2-[125I]-Iodomelatonin binding to human Melatonin receptor type 1B expressed in CHO cells |
Bioorg Med Chem Lett 7: 2409-2414 (1997)
Article DOI: 10.1016/S0960-894X(97)00444-7 BindingDB Entry DOI: 10.7270/Q25T3KFF |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1A
(Homo sapiens (Human)) | BDBM50290236
(CHEMBL80792 | N-{2-[2-(2-Dimethylamino-ethoxy)-7-m...)Show InChI InChI=1S/C20H28N2O3/c1-5-20(23)21-11-10-17-18-14-16(24-4)8-6-15(18)7-9-19(17)25-13-12-22(2)3/h6-9,14H,5,10-13H2,1-4H3,(H,21,23) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| 42 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Displacement of 2-[125I]-Iodomelatonin from human Melatonin receptor type 1A expressed in CHO cells |
Bioorg Med Chem Lett 7: 2409-2414 (1997)
Article DOI: 10.1016/S0960-894X(97)00444-7 BindingDB Entry DOI: 10.7270/Q25T3KFF |
More data for this Ligand-Target Pair | |
Aromatase
(Homo sapiens (Human)) | BDBM50014562
(7-Benzyl-10,13-dimethyl-1,8,9,10,11,12,13,14,15,16...)Show SMILES CC12CCC3C(C1CCC2=O)C(Cc1ccccc1)=CC1=CC(=O)CCC31C |c:21,t:23| Show InChI InChI=1S/C26H30O2/c1-25-12-10-20(27)16-19(25)15-18(14-17-6-4-3-5-7-17)24-21-8-9-23(28)26(21,2)13-11-22(24)25/h3-7,15-16,21-22,24H,8-14H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 61 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ohio State University
Curated by ChEMBL
| Assay Description In vitro inhibition of human placental cytochrome P450 19A1 |
J Med Chem 33: 101-5 (1990)
BindingDB Entry DOI: 10.7270/Q2KP8141 |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1B
(Homo sapiens (Human)) | BDBM50290240
(CHEMBL79224 | N-{2-[2-(2-Iodo-ethoxy)-7-methoxy-na...)Show InChI InChI=1S/C18H22INO3/c1-3-18(21)20-10-8-15-16-12-14(22-2)6-4-13(16)5-7-17(15)23-11-9-19/h4-7,12H,3,8-11H2,1-2H3,(H,20,21) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| 73 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of 2-[125I]-Iodomelatonin binding to human Melatonin receptor type 1B expressed in CHO cells |
Bioorg Med Chem Lett 7: 2409-2414 (1997)
Article DOI: 10.1016/S0960-894X(97)00444-7 BindingDB Entry DOI: 10.7270/Q25T3KFF |
More data for this Ligand-Target Pair | |
Aromatase
(Homo sapiens (Human)) | BDBM50014559
(7-(4-Amino-benzyl)-10,13-dimethyl-1,8,9,10,11,12,1...)Show SMILES CC12CCC3C(C1CCC2=O)C(Cc1ccc(N)cc1)=CC1=CC(=O)CCC31C |c:22,t:24| Show InChI InChI=1S/C26H31NO2/c1-25-11-9-20(28)15-18(25)14-17(13-16-3-5-19(27)6-4-16)24-21-7-8-23(29)26(21,2)12-10-22(24)25/h3-6,14-15,21-22,24H,7-13,27H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 88 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ohio State University
Curated by ChEMBL
| Assay Description In vitro inhibition of human placental cytochrome P450 19A1 |
J Med Chem 33: 101-5 (1990)
BindingDB Entry DOI: 10.7270/Q2KP8141 |
More data for this Ligand-Target Pair | |
Aromatase
(Homo sapiens (Human)) | BDBM50014565
(7-[2-(4-Amino-phenyl)-ethyl]-10,13-dimethyl-1,8,9,...)Show SMILES CC12CCC3C(C1CCC2=O)C(CCc1ccc(N)cc1)=CC1=CC(=O)CCC31C |c:23,t:25| Show InChI InChI=1S/C27H33NO2/c1-26-13-11-21(29)16-19(26)15-18(6-3-17-4-7-20(28)8-5-17)25-22-9-10-24(30)27(22,2)14-12-23(25)26/h4-5,7-8,15-16,22-23,25H,3,6,9-14,28H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 88 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ohio State University
Curated by ChEMBL
| Assay Description In vitro inhibition of human placental cytochrome P450 19A1 |
J Med Chem 33: 101-5 (1990)
BindingDB Entry DOI: 10.7270/Q2KP8141 |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1A
(Homo sapiens (Human)) | BDBM50290235
(CHEMBL78338 | {2-[7-Methoxy-1-(2-propionylamino-et...)Show SMILES CCC(=O)NCCc1c(OCC[N+](C)(C)C)ccc2ccc(OC)cc12 Show InChI InChI=1S/C21H30N2O3/c1-6-21(24)22-12-11-18-19-15-17(25-5)9-7-16(19)8-10-20(18)26-14-13-23(2,3)4/h7-10,15H,6,11-14H2,1-5H3/p+1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| 93 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Displacement of 2-[125I]-Iodomelatonin from human Melatonin receptor type 1A expressed in CHO cells |
Bioorg Med Chem Lett 7: 2409-2414 (1997)
Article DOI: 10.1016/S0960-894X(97)00444-7 BindingDB Entry DOI: 10.7270/Q25T3KFF |
More data for this Ligand-Target Pair | |
Aromatase
(Homo sapiens (Human)) | BDBM50014560
(10,13-Dimethyl-7-(4-nitro-benzyl)-1,8,9,10,11,12,1...)Show SMILES CC12CCC3C(C1CCC2=O)C(Cc1ccc(cc1)[N+]([O-])=O)=CC1=CC(=O)CCC31C |c:24,t:26| Show InChI InChI=1S/C26H29NO4/c1-25-11-9-20(28)15-18(25)14-17(13-16-3-5-19(6-4-16)27(30)31)24-21-7-8-23(29)26(21,2)12-10-22(24)25/h3-6,14-15,21-22,24H,7-13H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 94 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ohio State University
Curated by ChEMBL
| Assay Description In vitro inhibition of human placental cytochrome P450 19A1 |
J Med Chem 33: 101-5 (1990)
BindingDB Entry DOI: 10.7270/Q2KP8141 |
More data for this Ligand-Target Pair | |
Aromatase
(Homo sapiens (Human)) | BDBM50014563
(10,13-Dimethyl-7-[2-(4-nitro-phenyl)-ethyl]-1,8,9,...)Show SMILES CC12CCC3C(C1CCC2=O)C(CCc1ccc(cc1)[N+]([O-])=O)=CC1=CC(=O)CCC31C |c:25,t:27| Show InChI InChI=1S/C27H31NO4/c1-26-13-11-21(29)16-19(26)15-18(6-3-17-4-7-20(8-5-17)28(31)32)25-22-9-10-24(30)27(22,2)14-12-23(25)26/h4-5,7-8,15-16,22-23,25H,3,6,9-14H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 95 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ohio State University
Curated by ChEMBL
| Assay Description In vitro inhibition of human placental cytochrome P450 19A1 |
J Med Chem 33: 101-5 (1990)
BindingDB Entry DOI: 10.7270/Q2KP8141 |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1A
(Homo sapiens (Human)) | BDBM50290240
(CHEMBL79224 | N-{2-[2-(2-Iodo-ethoxy)-7-methoxy-na...)Show InChI InChI=1S/C18H22INO3/c1-3-18(21)20-10-8-15-16-12-14(22-2)6-4-13(16)5-7-17(15)23-11-9-19/h4-7,12H,3,8-11H2,1-2H3,(H,20,21) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Displacement of 2-[125I]-Iodomelatonin from human Melatonin receptor type 1A expressed in CHO cells |
Bioorg Med Chem Lett 7: 2409-2414 (1997)
Article DOI: 10.1016/S0960-894X(97)00444-7 BindingDB Entry DOI: 10.7270/Q25T3KFF |
More data for this Ligand-Target Pair | |
Aromatase
(Homo sapiens (Human)) | BDBM50014561
(10,13-Dimethyl-7-phenethyl-1,8,9,10,11,12,13,14,15...)Show SMILES CC12CCC3C(C1CCC2=O)C(CCc1ccccc1)=CC1=CC(=O)CCC31C |c:22,t:24| Show InChI InChI=1S/C27H32O2/c1-26-14-12-21(28)17-20(26)16-19(9-8-18-6-4-3-5-7-18)25-22-10-11-24(29)27(22,2)15-13-23(25)26/h3-7,16-17,22-23,25H,8-15H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 174 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ohio State University
Curated by ChEMBL
| Assay Description In vitro inhibition of human placental cytochrome P450 19A1 |
J Med Chem 33: 101-5 (1990)
BindingDB Entry DOI: 10.7270/Q2KP8141 |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1A
(Homo sapiens (Human)) | BDBM50290004
(4-(2-Acetylamino-ethyl)-6-methoxy-1-methyl-quinoli...)Show InChI InChI=1S/C15H18N2O2/c1-11(18)16-8-6-12-7-9-17(2)15-5-4-13(19-3)10-14(12)15/h4-5,7,9-10H,6,8H2,1-3H3/p+1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Binding affinity of the compound against human Melatonin receptor type 1A by displacement of [125I]-iodomelatonin stably expressed in CHO cells |
Bioorg Med Chem Lett 7: 2177-2180 (1997)
Article DOI: 10.1016/S0960-894X(97)00392-2 BindingDB Entry DOI: 10.7270/Q208659R |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1B
(Homo sapiens (Human)) | BDBM50290001
(6-Methoxy-1-methyl-4-(2-propionylamino-ethyl)-quin...)Show InChI InChI=1S/C16H20N2O2/c1-4-16(19)17-9-7-12-8-10-18(2)15-6-5-13(20-3)11-14(12)15/h5-6,8,10-11H,4,7,9H2,1-3H3/p+1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Binding affinity of the compound against human Melatonin receptor type 1B by displacement of [125I]-iodomelatonin stably expressed in CHO cells |
Bioorg Med Chem Lett 7: 2177-2180 (1997)
Article DOI: 10.1016/S0960-894X(97)00392-2 BindingDB Entry DOI: 10.7270/Q208659R |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1B
(Homo sapiens (Human)) | BDBM50290004
(4-(2-Acetylamino-ethyl)-6-methoxy-1-methyl-quinoli...)Show InChI InChI=1S/C15H18N2O2/c1-11(18)16-8-6-12-7-9-17(2)15-5-4-13(19-3)10-14(12)15/h4-5,7,9-10H,6,8H2,1-3H3/p+1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Binding affinity of the compound against human Melatonin receptor type 1B by displacement of [125I]-iodomelatonin stably expressed in CHO cells |
Bioorg Med Chem Lett 7: 2177-2180 (1997)
Article DOI: 10.1016/S0960-894X(97)00392-2 BindingDB Entry DOI: 10.7270/Q208659R |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1A
(Homo sapiens (Human)) | BDBM50290001
(6-Methoxy-1-methyl-4-(2-propionylamino-ethyl)-quin...)Show InChI InChI=1S/C16H20N2O2/c1-4-16(19)17-9-7-12-8-10-18(2)15-6-5-13(20-3)11-14(12)15/h5-6,8,10-11H,4,7,9H2,1-3H3/p+1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Binding affinity of the compound against human Melatonin receptor type 1A by displacement of [125I]-iodomelatonin stably expressed in CHO cells |
Bioorg Med Chem Lett 7: 2177-2180 (1997)
Article DOI: 10.1016/S0960-894X(97)00392-2 BindingDB Entry DOI: 10.7270/Q208659R |
More data for this Ligand-Target Pair | |
Aromatase
(Homo sapiens (Human)) | BDBM50014564
(10,13-Dimethyl-7-phenyl-1,8,9,10,11,12,13,14,15,16...)Show SMILES CC12CCC3C(C1CCC2=O)C(=CC1=CC(=O)CCC31C)c1ccccc1 |c:13,t:15| Show InChI InChI=1S/C25H28O2/c1-24-12-10-18(26)14-17(24)15-19(16-6-4-3-5-7-16)23-20-8-9-22(27)25(20,2)13-11-21(23)24/h3-7,14-15,20-21,23H,8-13H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| PubMed
| 1.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ohio State University
Curated by ChEMBL
| Assay Description In vitro inhibition of human placental cytochrome P450 19A1 |
J Med Chem 33: 101-5 (1990)
BindingDB Entry DOI: 10.7270/Q2KP8141 |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1A
(Homo sapiens (Human)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank KEGG PC cid PC sid PDB UniChem
Similars
| Article
| 7.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Displacement of 2-[125I]-Iodomelatonin from human Melatonin receptor type 1A expressed in CHO cells |
Bioorg Med Chem Lett 7: 2409-2414 (1997)
Article DOI: 10.1016/S0960-894X(97)00444-7 BindingDB Entry DOI: 10.7270/Q25T3KFF |
More data for this Ligand-Target Pair | |
Melatonin receptor type 1B
(Homo sapiens (Human)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank KEGG PC cid PC sid PDB UniChem
Similars
| Article
| 9.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of 2-[125I]-Iodomelatonin binding to human Melatonin receptor type 1B expressed in CHO cells |
Bioorg Med Chem Lett 7: 2409-2414 (1997)
Article DOI: 10.1016/S0960-894X(97)00444-7 BindingDB Entry DOI: 10.7270/Q25T3KFF |
More data for this Ligand-Target Pair | |