Compile Data Set for Download or QSAR

Found 110 hits with Last Name = 'lopaschuk' and Initial = 'gd'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50183286 (4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-N,...) Show SMILES CC(C)CN(CC(C)C)C(=O)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C18H23F6NO2/c1-11(2)9-25(10-12(3)4)15(26)13-5-7-14(8-6-13)16(27,17(19,20)21)18(22,23)24/h5-8,11-12,27H,9-10H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0700	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50183304 (CHEMBL380487 | N-(2-cyanoethyl)-N-ethyl-4-(1,1,1,3...) Show SMILES CCN(CCC#N)C(=O)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C15H14F6N2O2/c1-2-23(9-3-8-22)12(24)10-4-6-11(7-5-10)13(25,14(16,17)18)15(19,20)21/h4-7,25H,2-3,9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.290	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50183290 (CHEMBL205506 | pyrrolidin-1-yl-[4-(2,2,2-trifluoro...) Show SMILES OC(c1ccc(cc1)C(=O)N1CCCC1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C14H13F6NO2/c15-13(16,17)12(23,14(18,19)20)10-5-3-9(4-6-10)11(22)21-7-1-2-8-21/h3-6,23H,1-2,7-8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.850	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50183294 (CHEMBL204287 | piperidin-1-yl-[4-(2,2,2-trifluoro-...) Show SMILES OC(c1ccc(cc1)C(=O)N1CCCCC1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C15H15F6NO2/c16-14(17,18)13(24,15(19,20)21)11-6-4-10(5-7-11)12(23)22-8-2-1-3-9-22/h4-7,24H,1-3,8-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.980	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50183287 (CHEMBL202688 | N-benzyl-N-methyl-4-(2,2,2-trifluor...) Show SMILES CN(Cc1ccccc1)C(=O)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C18H15F6NO2/c1-25(11-12-5-3-2-4-6-12)15(26)13-7-9-14(10-8-13)16(27,17(19,20)21)18(22,23)24/h2-10,27H,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50183328 (CHEMBL206852 | morpholin-4-yl-[4-(2,2,2-trifluoro-...) Show SMILES OC(c1ccc(cc1)C(=O)N1CCOCC1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C14H13F6NO3/c15-13(16,17)12(23,14(18,19)20)10-3-1-9(2-4-10)11(22)21-5-7-24-8-6-21/h1-4,23H,5-8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.14	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50183298 (CHEMBL202689 | N-methoxy-N-methyl-4-(2,2,2-trifluo...) Show SMILES CON(C)C(=O)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C12H11F6NO3/c1-19(22-2)9(20)7-3-5-8(6-4-7)10(21,11(13,14)15)12(16,17)18/h3-6,21H,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.45	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50183316 (CHEMBL202746 | N-methyl-N-phenethyl-4-(2,2,2-trifl...) Show SMILES CN(CCc1ccccc1)C(=O)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C19H17F6NO2/c1-26(12-11-13-5-3-2-4-6-13)16(27)14-7-9-15(10-8-14)17(28,18(20,21)22)19(23,24)25/h2-10,28H,11-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.99	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50183313 (CHEMBL203835 | N-phenethyl-4-(2,2,2-trifluoro-1-hy...) Show SMILES OC(c1ccc(cc1)C(=O)NCCc1ccccc1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C18H15F6NO2/c19-17(20,21)16(27,18(22,23)24)14-8-6-13(7-9-14)15(26)25-11-10-12-4-2-1-3-5-12/h1-9,27H,10-11H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.65	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50190407 ((3S)-3-methylpentan-3-yl 3-(5-(1,1,1,3,3,3-hexaflu...) Show SMILES CCC(C)(CC)OC(=O)C[C@H](C)NC(=O)C1=NOC(C1)C(O)(C(F)(F)F)C(F)(F)F |t:15| Show InChI InChI=1S/C17H24F6N2O5/c1-5-14(4,6-2)29-12(26)7-9(3)24-13(27)10-8-11(30-25-10)15(28,16(18,19)20)17(21,22)23/h9,11,28H,5-8H2,1-4H3,(H,24,27)/t9-,11?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of malonyl-coenzyme A decarboxylase				J Med Chem 49: 4055-8 (2006) Article DOI: 10.1021/jm0605029 BindingDB Entry DOI: 10.7270/Q2Q81CQ7
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50190401 (CHEMBL211177 | tert-butyl-(3S)-3-{[(5R)-5-(2,2,2-t...) Show SMILES C[C@@H](CC(=O)OC(C)(C)C)NC(=O)C1=NO[C@H](C1)C(O)(C(F)(F)F)C(F)(F)F |t:13| Show InChI InChI=1S/C15H20F6N2O5/c1-7(5-10(24)27-12(2,3)4)22-11(25)8-6-9(28-23-8)13(26,14(16,17)18)15(19,20)21/h7,9,26H,5-6H2,1-4H3,(H,22,25)/t7-,9+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of malonyl-coenzyme A decarboxylase				J Med Chem 49: 4055-8 (2006) Article DOI: 10.1021/jm0605029 BindingDB Entry DOI: 10.7270/Q2Q81CQ7
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50190397 (CHEMBL208825 | tert-butyl-(3S)-3-{[5-(2,2,2-triflu...) Show SMILES C[C@@H](CC(=O)OC(C)(C)C)NC(=O)C1=NOC(C1)C(O)(C(F)(F)F)C(F)(F)F |t:13| Show InChI InChI=1S/C15H20F6N2O5/c1-7(5-10(24)27-12(2,3)4)22-11(25)8-6-9(28-23-8)13(26,14(16,17)18)15(19,20)21/h7,9,26H,5-6H2,1-4H3,(H,22,25)/t7-,9?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of malonyl-coenzyme A decarboxylase				J Med Chem 49: 4055-8 (2006) Article DOI: 10.1021/jm0605029 BindingDB Entry DOI: 10.7270/Q2Q81CQ7
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50190399 (3-{[5-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethyl...) Show SMILES CCC(C)(CC)OC(=O)CCNC(=O)C1=NOC(C1)C(O)(C(F)(F)F)C(F)(F)F |t:14| Show InChI InChI=1S/C16H22F6N2O5/c1-4-13(3,5-2)28-11(25)6-7-23-12(26)9-8-10(29-24-9)14(27,15(17,18)19)16(20,21)22/h10,27H,4-8H2,1-3H3,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of malonyl-coenzyme A decarboxylase				J Med Chem 49: 4055-8 (2006) Article DOI: 10.1021/jm0605029 BindingDB Entry DOI: 10.7270/Q2Q81CQ7
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50190410 (CHEMBL378459 | tert-butyl-(3R)-3-{[(5R)-5-(2,2,2-t...) Show SMILES C[C@H](CC(=O)OC(C)(C)C)NC(=O)C1=NO[C@H](C1)C(O)(C(F)(F)F)C(F)(F)F |t:13| Show InChI InChI=1S/C15H20F6N2O5/c1-7(5-10(24)27-12(2,3)4)22-11(25)8-6-9(28-23-8)13(26,14(16,17)18)15(19,20)21/h7,9,26H,5-6H2,1-4H3,(H,22,25)/t7-,9-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of malonyl-coenzyme A decarboxylase				J Med Chem 49: 4055-8 (2006) Article DOI: 10.1021/jm0605029 BindingDB Entry DOI: 10.7270/Q2Q81CQ7
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50183307 (5-(N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-...) Show SMILES CC(C)C(=O)N(CCCCC(O)=O)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C18H21F6NO4/c1-11(2)15(28)25(10-4-3-5-14(26)27)13-8-6-12(7-9-13)16(29,17(19,20)21)18(22,23)24/h6-9,11,29H,3-5,10H2,1-2H3,(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50212235 (CHEMBL400455 | N-(4-(1H-tetrazol-5-yl)butyl)-N-(4-...) Show SMILES CC(C)C(=O)N(CCCCc1nnn[nH]1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C18H21F6N5O2/c1-11(2)15(30)29(10-4-3-5-14-25-27-28-26-14)13-8-6-12(7-9-13)16(31,17(19,20)21)18(22,23)24/h6-9,11,31H,3-5,10H2,1-2H3,(H,25,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50186046 (CHEMBL210138 | N-(4-cyanobenzyl)-N-(5-(1,1,1,3,3,3...) Show SMILES OC(c1cnc(s1)N(Cc1ccc(cc1)C#N)C(=O)c1ccncc1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H12F6N4O2S/c21-19(22,23)18(32,20(24,25)26)15-10-29-17(33-15)30(16(31)14-5-7-28-8-6-14)11-13-3-1-12(9-27)2-4-13/h1-8,10,32H,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				Bioorg Med Chem Lett 16: 3484-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.100 BindingDB Entry DOI: 10.7270/Q2FJ2GCN
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50190408 (3-{[5-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethyl...) Show SMILES CC(C)CC(C)(CC(C)C)OC(=O)CCNC(=O)C1=NOC(C1)C(O)(C(F)(F)F)C(F)(F)F |t:18| Show InChI InChI=1S/C20H30F6N2O5/c1-11(2)9-17(5,10-12(3)4)32-15(29)6-7-27-16(30)13-8-14(33-28-13)18(31,19(21,22)23)20(24,25)26/h11-12,14,31H,6-10H2,1-5H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of malonyl-coenzyme A decarboxylase				J Med Chem 49: 4055-8 (2006) Article DOI: 10.1021/jm0605029 BindingDB Entry DOI: 10.7270/Q2Q81CQ7
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50190413 (CHEMBL379321 | tert-butyl-(3R)-3-{[5-(2,2,2-triflu...) Show SMILES C[C@H](CC(=O)OC(C)(C)C)NC(=O)C1=NOC(C1)C(O)(C(F)(F)F)C(F)(F)F |t:13| Show InChI InChI=1S/C15H20F6N2O5/c1-7(5-10(24)27-12(2,3)4)22-11(25)8-6-9(28-23-8)13(26,14(16,17)18)15(19,20)21/h7,9,26H,5-6H2,1-4H3,(H,22,25)/t7-,9?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of malonyl-coenzyme A decarboxylase				J Med Chem 49: 4055-8 (2006) Article DOI: 10.1021/jm0605029 BindingDB Entry DOI: 10.7270/Q2Q81CQ7
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50186054 (4-((3,5-dichloro-N-(5-(1,1,1,3,3,3-hexafluoro-2-hy...) Show SMILES OC(=O)c1ccc(CN(C(=O)c2cc(Cl)cc(Cl)c2)c2ncc(s2)C(O)(C(F)(F)F)C(F)(F)F)cc1 Show InChI InChI=1S/C21H12Cl2F6N2O4S/c22-13-5-12(6-14(23)7-13)16(32)31(9-10-1-3-11(4-2-10)17(33)34)18-30-8-15(36-18)19(35,20(24,25)26)21(27,28)29/h1-8,35H,9H2,(H,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				Bioorg Med Chem Lett 16: 3484-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.100 BindingDB Entry DOI: 10.7270/Q2FJ2GCN
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50183296 (5-{(morpholine-4-carbonyl)-[4-(2,2,2-trifluoro-1-h...) Show SMILES OC(=O)CCCCN(C(=O)N1CCOCC1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C19H22F6N2O5/c20-18(21,22)17(31,19(23,24)25)13-4-6-14(7-5-13)27(8-2-1-3-15(28)29)16(30)26-9-11-32-12-10-26/h4-7,31H,1-3,8-12H2,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50190415 (5-methyl-(3S)-3-{[5-(2,2,2-trifluoro-1-hydroxy-1-t...) Show SMILES CC(C)C[C@@H](CC(=O)OC(C)(C)C)NC(=O)C1=NOC(C1)C(O)(C(F)(F)F)C(F)(F)F |t:16| Show InChI InChI=1S/C18H26F6N2O5/c1-9(2)6-10(7-13(27)30-15(3,4)5)25-14(28)11-8-12(31-26-11)16(29,17(19,20)21)18(22,23)24/h9-10,12,29H,6-8H2,1-5H3,(H,25,28)/t10-,12?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of malonyl-coenzyme A decarboxylase				J Med Chem 49: 4055-8 (2006) Article DOI: 10.1021/jm0605029 BindingDB Entry DOI: 10.7270/Q2Q81CQ7
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50190416 (CHEMBL378896 | N-(3-(diisopropylamino)-3-oxopropyl...) Show SMILES CC(C)N(C(C)C)C(=O)CCNC(=O)C1=NOC(C1)C(O)(C(F)(F)F)C(F)(F)F |t:14| Show InChI InChI=1S/C16H23F6N3O4/c1-8(2)25(9(3)4)12(26)5-6-23-13(27)10-7-11(29-24-10)14(28,15(17,18)19)16(20,21)22/h8-9,11,28H,5-7H2,1-4H3,(H,23,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of malonyl-coenzyme A decarboxylase				J Med Chem 49: 4055-8 (2006) Article DOI: 10.1021/jm0605029 BindingDB Entry DOI: 10.7270/Q2Q81CQ7
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50183302 (CHEMBL203790 | N-(4-(1,1,1,3,3,3-hexafluoro-2-hydr...) Show SMILES CCCCCN(C(=O)N1CCOCC1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C19H24F6N2O3/c1-2-3-4-9-27(16(28)26-10-12-30-13-11-26)15-7-5-14(6-8-15)17(29,18(20,21)22)19(23,24)25/h5-8,29H,2-4,9-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50183299 (CHEMBL206438 | N-butyl-N-(4-(1,1,1,3,3,3-hexafluor...) Show SMILES CCCCN(C(=O)C(C)C)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H21F6NO2/c1-4-5-10-24(14(25)11(2)3)13-8-6-12(7-9-13)15(26,16(18,19)20)17(21,22)23/h6-9,11,26H,4-5,10H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50186052 (CHEMBL210190 | N-(4-cyanobenzyl)-N-(5-(1,1,1,3,3,3...) Show SMILES CC(C)C(=O)N(Cc1ccc(cc1)C#N)c1ncc(s1)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C18H15F6N3O2S/c1-10(2)14(28)27(9-12-5-3-11(7-25)4-6-12)15-26-8-13(30-15)16(29,17(19,20)21)18(22,23)24/h3-6,8,10,29H,9H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				Bioorg Med Chem Lett 16: 3484-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.100 BindingDB Entry DOI: 10.7270/Q2FJ2GCN
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50186053 (CHEMBL385355 | N-(5-(1,1,1,3,3,3-hexafluoro-2-hydr...) Show SMILES CC(C)C(=O)N(Cc1ccncc1)c1ncc(s1)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C16H15F6N3O2S/c1-9(2)12(26)25(8-10-3-5-23-6-4-10)13-24-7-11(28-13)14(27,15(17,18)19)16(20,21)22/h3-7,9,27H,8H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				Bioorg Med Chem Lett 16: 3484-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.100 BindingDB Entry DOI: 10.7270/Q2FJ2GCN
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50183327 (CHEMBL382695 | N-(4-Cyanobutyl)-N-[4-(2,2,2-triflu...) Show SMILES CC(C)C(=O)N(CCCCC#N)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C18H20F6N2O2/c1-12(2)15(27)26(11-5-3-4-10-25)14-8-6-13(7-9-14)16(28,17(19,20)21)18(22,23)24/h6-9,12,28H,3-5,11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50186044 (CHEMBL211235 | N-(5-(1,1,1,3,3,3-hexafluoro-2-hydr...) Show SMILES OC(c1cnc(s1)N(Cc1ccncc1)C(=O)c1ccncc1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C18H12F6N4O2S/c19-17(20,21)16(30,18(22,23)24)13-9-27-15(31-13)28(10-11-1-5-25-6-2-11)14(29)12-3-7-26-8-4-12/h1-9,30H,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				Bioorg Med Chem Lett 16: 3484-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.100 BindingDB Entry DOI: 10.7270/Q2FJ2GCN
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50186047 (CHEMBL209430 | N-ethyl-N-(6-(1,1,1,3,3,3-hexafluor...) Show SMILES CCN(C(=O)C(C)C)c1ccc(nc1)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C14H16F6N2O2/c1-4-22(11(23)8(2)3)9-5-6-10(21-7-9)12(24,13(15,16)17)14(18,19)20/h5-8,24H,4H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				Bioorg Med Chem Lett 16: 3484-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.100 BindingDB Entry DOI: 10.7270/Q2FJ2GCN
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50190411 (CHEMBL213556 | tert-butyl-3-{[5-(2,2,2-trifluoro-1...) Show SMILES CC(CC(=O)OC(C)(C)C)NC(=O)C1=NOC(C1)C(O)(C(F)(F)F)C(F)(F)F |t:13| Show InChI InChI=1S/C15H20F6N2O5/c1-7(5-10(24)27-12(2,3)4)22-11(25)8-6-9(28-23-8)13(26,14(16,17)18)15(19,20)21/h7,9,26H,5-6H2,1-4H3,(H,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of malonyl-coenzyme A decarboxylase				J Med Chem 49: 4055-8 (2006) Article DOI: 10.1021/jm0605029 BindingDB Entry DOI: 10.7270/Q2Q81CQ7
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50186056 (1-(2-cyanoethyl)-1-ethyl-3-(6-(1,1,1,3,3,3-hexaflu...) Show SMILES CCN(CCC#N)C(=S)N(CC1CCOC1)c1ccc(nc1)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C19H22F6N4O2S/c1-2-28(8-3-7-26)16(32)29(11-13-6-9-31-12-13)14-4-5-15(27-10-14)17(30,18(20,21)22)19(23,24)25/h4-5,10,13,30H,2-3,6,8-9,11-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				Bioorg Med Chem Lett 16: 3484-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.100 BindingDB Entry DOI: 10.7270/Q2FJ2GCN
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50183301 (5-{isobutyryl-[4-(2,2,2-trifluoro-1-hydroxy-1-trif...) Show SMILES COC(=O)CCCCN(C(=O)C(C)C)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C19H23F6NO4/c1-12(2)16(28)26(11-5-4-6-15(27)30-3)14-9-7-13(8-10-14)17(29,18(20,21)22)19(23,24)25/h7-10,12,29H,4-6,11H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50190403 (5-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethyl-eth...) Show SMILES CC(C)CCCC(C)NC(=O)C1=NOC(C1)C(O)(C(F)(F)F)C(F)(F)F |t:11| Show InChI InChI=1S/C15H22F6N2O3/c1-8(2)5-4-6-9(3)22-12(24)10-7-11(26-23-10)13(25,14(16,17)18)15(19,20)21/h8-9,11,25H,4-7H2,1-3H3,(H,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of malonyl-coenzyme A decarboxylase				J Med Chem 49: 4055-8 (2006) Article DOI: 10.1021/jm0605029 BindingDB Entry DOI: 10.7270/Q2Q81CQ7
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50190406 (5-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethyl-eth...) Show SMILES CC(C)(C)OCCCNC(=O)C1=NOC(C1)C(O)(C(F)(F)F)C(F)(F)F |t:11| Show InChI InChI=1S/C14H20F6N2O4/c1-11(2,3)25-6-4-5-21-10(23)8-7-9(26-22-8)12(24,13(15,16)17)14(18,19)20/h9,24H,4-7H2,1-3H3,(H,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of malonyl-coenzyme A decarboxylase				J Med Chem 49: 4055-8 (2006) Article DOI: 10.1021/jm0605029 BindingDB Entry DOI: 10.7270/Q2Q81CQ7
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50183297 (CHEMBL381996 | N-(4-(1,1,1,3,3,3-hexafluoro-2-hydr...) Show SMILES CCCN(C(=O)C(C)C)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C16H19F6NO2/c1-4-9-23(13(24)10(2)3)12-7-5-11(6-8-12)14(25,15(17,18)19)16(20,21)22/h5-8,10,25H,4,9H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50190404 (5-methyl-3-{[5-(2,2,2-trifluoro-1-hydroxy-1-triflu...) Show SMILES CC(C)CC(CC(=O)OC(C)(C)C)NC(=O)C1=NOC(C1)C(O)(C(F)(F)F)C(F)(F)F |t:16| Show InChI InChI=1S/C18H26F6N2O5/c1-9(2)6-10(7-13(27)30-15(3,4)5)25-14(28)11-8-12(31-26-11)16(29,17(19,20)21)18(22,23)24/h9-10,12,29H,6-8H2,1-5H3,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of malonyl-coenzyme A decarboxylase				J Med Chem 49: 4055-8 (2006) Article DOI: 10.1021/jm0605029 BindingDB Entry DOI: 10.7270/Q2Q81CQ7
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50183279 (CHEMBL202905 | N-butyl-N-(4-(1,1,1,3,3,3-hexafluor...) Show SMILES CCCCN(C(=O)N1CCOCC1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C18H22F6N2O3/c1-2-3-8-26(15(27)25-9-11-29-12-10-25)14-6-4-13(5-7-14)16(28,17(19,20)21)18(22,23)24/h4-7,28H,2-3,8-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50190418 (3-{[5-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethyl...) Show SMILES CC(C)(C)OC(=O)CCNC(=O)C1=NOC(C1)C(O)(C(F)(F)F)C(F)(F)F |t:12| Show InChI InChI=1S/C14H18F6N2O5/c1-11(2,3)26-9(23)4-5-21-10(24)7-6-8(27-22-7)12(25,13(15,16)17)14(18,19)20/h8,25H,4-6H2,1-3H3,(H,21,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of malonyl-coenzyme A decarboxylase				J Med Chem 49: 4055-8 (2006) Article DOI: 10.1021/jm0605029 BindingDB Entry DOI: 10.7270/Q2Q81CQ7
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50183288 (CHEMBL381564 | N-(4-(1,1,1,3,3,3-hexafluoro-2-hydr...) Show SMILES CCCCCCN(C(=O)N1CCOCC1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H26F6N2O3/c1-2-3-4-5-10-28(17(29)27-11-13-31-14-12-27)16-8-6-15(7-9-16)18(30,19(21,22)23)20(24,25)26/h6-9,30H,2-5,10-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50183323 (CHEMBL383498 | {isobutyryl-[4-(2,2,2-trifluoro-1-h...) Show SMILES COC(=O)CN(C(=O)C(C)C)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C16H17F6NO4/c1-9(2)13(25)23(8-12(24)27-3)11-6-4-10(5-7-11)14(26,15(17,18)19)16(20,21)22/h4-7,9,26H,8H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50183292 (CHEMBL205932 | N-(4-(1,1,1,3,3,3-hexafluoro-2-hydr...) Show SMILES CCCN(C(=O)N1CCOCC1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H20F6N2O3/c1-2-7-25(14(26)24-8-10-28-11-9-24)13-5-3-12(4-6-13)15(27,16(18,19)20)17(21,22)23/h3-6,27H,2,7-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50190405 (2,4,6-trimethylheptan-4-yl 3-(5-(1,1,1,3,3,3-hexaf...) Show SMILES CC(C)CC(C)(CC(C)C)OC(=O)CC(C)NC(=O)C1=NOC(C1)C(O)(C(F)(F)F)C(F)(F)F |t:19| Show InChI InChI=1S/C21H32F6N2O5/c1-11(2)9-18(6,10-12(3)4)33-16(30)7-13(5)28-17(31)14-8-15(34-29-14)19(32,20(22,23)24)21(25,26)27/h11-13,15,32H,7-10H2,1-6H3,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of malonyl-coenzyme A decarboxylase				J Med Chem 49: 4055-8 (2006) Article DOI: 10.1021/jm0605029 BindingDB Entry DOI: 10.7270/Q2Q81CQ7
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50183321 (4-Cyano-N-ethyl-N-[4-(2,2,2-trifluoro-1-hydroxy-1-...) Show SMILES CCN(C(=O)c1ccc(cc1)C#N)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C19H14F6N2O2/c1-2-27(16(28)13-5-3-12(11-26)4-6-13)15-9-7-14(8-10-15)17(29,18(20,21)22)19(23,24)25/h3-10,29H,2H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50183320 (CHEMBL380746 | N-(3-cyanopropyl)-N-(4-(1,1,1,3,3,3...) Show SMILES OC(c1ccc(cc1)N(CCCC#N)C(=O)N1CCOCC1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C18H19F6N3O3/c19-17(20,21)16(29,18(22,23)24)13-3-5-14(6-4-13)27(8-2-1-7-25)15(28)26-9-11-30-12-10-26/h3-6,29H,1-2,8-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50183308 (CHEMBL383478 | N-ethyl-N-(4-(1,1,1,3,3,3-hexafluor...) Show SMILES CCN(C(=O)C(C)C)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C15H17F6NO2/c1-4-22(12(23)9(2)3)11-7-5-10(6-8-11)13(24,14(16,17)18)15(19,20)21/h5-9,24H,4H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50183332 (5-{(morpholine-4-carbonyl)-[4-(2,2,2-trifluoro-1-h...) Show SMILES COC(=O)CCCCN(C(=O)N1CCOCC1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H24F6N2O5/c1-32-16(29)4-2-3-9-28(17(30)27-10-12-33-13-11-27)15-7-5-14(6-8-15)18(31,19(21,22)23)20(24,25)26/h5-8,31H,2-4,9-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50183291 (CHEMBL205117 | N-(4-(1,1,1,3,3,3-hexafluoro-2-hydr...) Show SMILES OC(c1ccc(cc1)N(CCc1ccccc1)C(=O)N1CCOCC1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C22H22F6N2O3/c23-21(24,25)20(32,22(26,27)28)17-6-8-18(9-7-17)30(11-10-16-4-2-1-3-5-16)19(31)29-12-14-33-15-13-29/h1-9,32H,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50190392 (5-methyl-(3R)-3-{[5-(2,2,2-trifluoro-1-hydroxy-1-t...) Show SMILES CC(C)C[C@H](CC(=O)OC(C)(C)C)NC(=O)C1=NOC(C1)C(O)(C(F)(F)F)C(F)(F)F |t:16| Show InChI InChI=1S/C18H26F6N2O5/c1-9(2)6-10(7-13(27)30-15(3,4)5)25-14(28)11-8-12(31-26-11)16(29,17(19,20)21)18(22,23)24/h9-10,12,29H,6-8H2,1-5H3,(H,25,28)/t10-,12?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma USA, LLC. Curated by ChEMBL					Assay Description Inhibition of malonyl-coenzyme A decarboxylase				J Med Chem 49: 4055-8 (2006) Article DOI: 10.1021/jm0605029 BindingDB Entry DOI: 10.7270/Q2Q81CQ7
					More data for this Ligand-Target Pair
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human))	BDBM50186049 (6-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-N,...) Show SMILES CC(C)CN(CC(C)C)C(=O)c1ccc(nc1)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H22F6N2O2/c1-10(2)8-25(9-11(3)4)14(26)12-5-6-13(24-7-12)15(27,16(18,19)20)17(21,22)23/h5-7,10-11,27H,8-9H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharma LLC. Curated by ChEMBL					Assay Description Inhibition of MCD				Bioorg Med Chem Lett 16: 3484-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.100 BindingDB Entry DOI: 10.7270/Q2FJ2GCN
					More data for this Ligand-Target Pair

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