Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alpha-1A adrenergic receptor (Homo sapiens (Human)) | BDBM50131891 (3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic a...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0940 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università degli Studi di Torino Curated by ChEMBL | Assay Description Inhibition of [3H]-prazosin binding to cloned human Alpha-1A adrenergic receptor in CHO-cells (chinese hamster ovary cells) | J Med Chem 46: 3762-5 (2003) Article DOI: 10.1021/jm030825u BindingDB Entry DOI: 10.7270/Q2BZ65FJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50143673 (8-{2-[4-(2,5-Dichloro-phenyl)-piperazin-1-yl]-ethy...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description Binding affinity to the adrenergic receptor alpha-1D of rat aorta | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50143697 (8-{2-[4-(2,5-Dichloro-phenyl)-piperazin-1-yl]-ethy...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description Binding affinity to the adrenergic receptor alpha-1D of rat aorta | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50143664 (8-{2-[4-(2,5-Difluoro-phenyl)-piperazin-1-yl]-ethy...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description Binding affinity to the adrenergic receptor alpha-1D of rat aorta | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A adrenergic receptor (Homo sapiens (Human)) | BDBM50131889 (3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic a...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università degli Studi di Torino Curated by ChEMBL | Assay Description Inhibition of [3H]-prazosin binding to cloned human Alpha-1A adrenergic receptor in CHO-cells (chinese hamster ovary cells) | J Med Chem 46: 3762-5 (2003) Article DOI: 10.1021/jm030825u BindingDB Entry DOI: 10.7270/Q2BZ65FJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50143666 (8-{2-[4-(2-Chloro-5-fluoro-phenyl)-piperazin-1-yl]...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description Binding affinity to the adrenergic receptor alpha-1D of rat aorta | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50143687 (4-Chloro-2-{4-[2-(7,9-dioxo-8-aza-spiro[4.5]dec-8-...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description Binding affinity to the adrenergic receptor alpha-1D of rat aorta | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A adrenergic receptor (Homo sapiens (Human)) | BDBM50057465 (3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic a...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 0.340 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università degli Studi di Torino Curated by ChEMBL | Assay Description Inhibition of [3H]-prazosin binding to cloned human Alpha-1A adrenergic receptor in CHO-cells (chinese hamster ovary cells) | J Med Chem 46: 3762-5 (2003) Article DOI: 10.1021/jm030825u BindingDB Entry DOI: 10.7270/Q2BZ65FJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50143701 (8-{2-[4-(2-Chloro-phenyl)-[1,4]diazepan-1-yl]-ethy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.340 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description Binding affinity to human 5-hydroxytryptamine 1A receptor was measured using [3H]-8-hydroxy-2-(di-n-propylamine) tetraline [3H]-8-OH-DPAT) as radioli... | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50143702 (8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.370 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description Binding affinity to the adrenergic receptor alpha-1D of rat aorta | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50143689 (8-{2-[4-(5-Chloro-2-methyl-phenyl)-piperazin-1-yl]...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.370 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description Binding affinity to the adrenergic receptor alpha-1D of rat aorta | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50143720 (8-{2-[4-(2,5-Dichloro-phenyl)-piperazin-1-yl]-1-me...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.410 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description Binding affinity to the adrenergic receptor alpha-1D of rat aorta | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1B adrenergic receptor (Homo sapiens (Human)) | BDBM50057463 (1-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piper...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 0.450 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati S.p.A. Curated by ChEMBL | Assay Description The binding affinity of the compound was determined towards Alpha-1B adrenergic receptor in the COS cell line. | J Med Chem 42: 427-37 (1999) Article DOI: 10.1021/jm9805337 BindingDB Entry DOI: 10.7270/Q2FN15CK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1B adrenergic receptor (Homo sapiens (Human)) | BDBM50073570 (2-(4-Furan-2-yl-piperazin-1-yl)-6,7-dimethoxy-quin...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 0.460 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati S.p.A. Curated by ChEMBL | Assay Description The binding affinity of the compound was determined towards Alpha-1B adrenergic receptor in the COS cell line. | J Med Chem 42: 427-37 (1999) Article DOI: 10.1021/jm9805337 BindingDB Entry DOI: 10.7270/Q2FN15CK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50143660 (8-{2-[4-(2-Isopropoxy-phenyl)-piperazin-1-yl]-ethy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.540 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description Binding affinity to human 5-hydroxytryptamine 1A receptor was measured using [3H]-8-hydroxy-2-(di-n-propylamine) tetraline [3H]-8-OH-DPAT) as radioli... | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50143680 (8-{2-[4-(2-Chloro-phenyl)-piperazin-1-yl]-ethyl}-8...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.540 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description Binding affinity to the adrenergic receptor alpha-1D of rat aorta | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50143703 (8-{4-[4-(2,5-Dichloro-phenyl)-piperazin-1-yl]-buty...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.670 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description Binding affinity to the adrenergic receptor alpha-1D of rat aorta | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50073570 (2-(4-Furan-2-yl-piperazin-1-yl)-6,7-dimethoxy-quin...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 0.720 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati S.p.A. Curated by ChEMBL | Assay Description The binding affinity of the compound was determined towards Alpha-1A adrenergic receptor in the COS cell line. | J Med Chem 42: 427-37 (1999) Article DOI: 10.1021/jm9805337 BindingDB Entry DOI: 10.7270/Q2FN15CK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A adrenergic receptor (Homo sapiens (Human)) | BDBM50131890 (3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic a...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.730 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università degli Studi di Torino Curated by ChEMBL | Assay Description Inhibition of [3H]-prazosin binding to cloned human Alpha-1A adrenergic receptor in CHO-cells (chinese hamster ovary cells) | J Med Chem 46: 3762-5 (2003) Article DOI: 10.1021/jm030825u BindingDB Entry DOI: 10.7270/Q2BZ65FJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50026917 (8-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-8-a...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description Binding affinity to human 5-hydroxytryptamine 1A receptor was measured using [3H]-8-hydroxy-2-(di-n-propylamine) tetraline [3H]-8-OH-DPAT) as radioli... | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50143654 (8-{2-[4-(2-Chloro-phenyl)-piperazin-1-yl]-ethyl}-8...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.830 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description Binding affinity to the adrenergic receptor alpha-1D of rat aorta | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50143676 (8-{2-[4-(2-Chloro-phenyl)-piperazin-1-yl]-ethyl}-8...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.840 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description Binding affinity to the adrenergic receptor alpha-1D of rat aorta | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50143674 (8-{2-[4-(2-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-8...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.910 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description Binding affinity to the adrenergic receptor alpha-1D of rat aorta | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50143658 (2-{4-[2-(7,9-Dioxo-8-aza-spiro[4.5]dec-8-yl)-ethyl...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.930 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description Binding affinity to the adrenergic receptor alpha-1D of rat aorta | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50143680 (8-{2-[4-(2-Chloro-phenyl)-piperazin-1-yl]-ethyl}-8...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.06 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description Binding affinity to human 5-hydroxytryptamine 1A receptor was measured using [3H]-8-hydroxy-2-(di-n-propylamine) tetraline [3H]-8-OH-DPAT) as radioli... | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50026941 (8-{2-[4-(3-Chloro-phenyl)-piperazin-1-yl]-ethyl}-8...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.09 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description Binding affinity to human 5-hydroxytryptamine 1A receptor was measured using [3H]-8-hydroxy-2-(di-n-propylamine) tetraline [3H]-8-OH-DPAT) as radioli... | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50143652 (8-{2-[4-(2-Chloro-phenyl)-piperidin-1-yl]-ethyl}-8...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description Binding affinity to the adrenergic receptor alpha-1D of rat aorta | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1B adrenergic receptor (Homo sapiens (Human)) | BDBM50131891 (3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic a...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università degli Studi di Torino Curated by ChEMBL | Assay Description Inhibition of [3H]-prazosin binding to cloned human Alpha-1B adrenergic receptor in CHO-cells (chinese hamster ovary cells) | J Med Chem 46: 3762-5 (2003) Article DOI: 10.1021/jm030825u BindingDB Entry DOI: 10.7270/Q2BZ65FJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50143681 (8-{2-[4-(2-Cyclopropyl-phenyl)-piperazin-1-yl]-eth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description Binding affinity to human 5-hydroxytryptamine 1A receptor was measured using [3H]-8-hydroxy-2-(di-n-propylamine) tetraline [3H]-8-OH-DPAT) as radioli... | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50131888 (4-[2-(4-{3-[(3-Methyl-4-oxo-2-phenyl-4H-chromene-8...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università degli Studi di Torino Curated by ChEMBL | Assay Description Inhibition of [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor serotonergic receptor in human HeLa cells | J Med Chem 46: 3762-5 (2003) Article DOI: 10.1021/jm030825u BindingDB Entry DOI: 10.7270/Q2BZ65FJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50143683 (1-{2-[4-(2,5-Dichloro-phenyl)-piperazin-1-yl]-ethy...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description Binding affinity to the adrenergic receptor alpha-1D of rat aorta | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50143693 (8-{2-[4-(2-Bromo-phenyl)-piperazin-1-yl]-ethyl}-8-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description Binding affinity to human 5-hydroxytryptamine 1A receptor was measured using [3H]-8-hydroxy-2-(di-n-propylamine) tetraline [3H]-8-OH-DPAT) as radioli... | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50143681 (8-{2-[4-(2-Cyclopropyl-phenyl)-piperazin-1-yl]-eth...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.34 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description Binding affinity to the adrenergic receptor alpha-1D of rat aorta | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50143718 (8-{2-[4-(2-Hydroxy-phenyl)-piperazin-1-yl]-ethyl}-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.36 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description Binding affinity to human 5-hydroxytryptamine 1A receptor was measured using [3H]-8-hydroxy-2-(di-n-propylamine) tetraline [3H]-8-OH-DPAT) as radioli... | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50143701 (8-{2-[4-(2-Chloro-phenyl)-[1,4]diazepan-1-yl]-ethy...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description Binding affinity to the adrenergic receptor alpha-1D of rat aorta | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A adrenergic receptor (Homo sapiens (Human)) | BDBM50073570 (2-(4-Furan-2-yl-piperazin-1-yl)-6,7-dimethoxy-quin...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 1.39 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati S.p.A. Curated by ChEMBL | Assay Description The binding affinity of the compound was determined towards Alpha-1C adrenergic receptor in the COS cell line. | J Med Chem 42: 427-37 (1999) Article DOI: 10.1021/jm9805337 BindingDB Entry DOI: 10.7270/Q2FN15CK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50143684 (8-{2-[4-(2,5-Dichloro-phenyl)-piperazin-1-yl]-ethy...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description Binding affinity to the adrenergic receptor alpha-1D of rat aorta | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50073563 (1-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piper...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.48 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati S.p.A. Curated by ChEMBL | Assay Description The binding affinity of the compound was determined towards Alpha-1A adrenergic receptor in the COS cell line. | J Med Chem 42: 427-37 (1999) Article DOI: 10.1021/jm9805337 BindingDB Entry DOI: 10.7270/Q2FN15CK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Homo sapiens (Human)) | BDBM50057465 (3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic a...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università degli Studi di Torino Curated by ChEMBL | Assay Description Inhibition of [3H]-prazosin binding to cloned human Alpha-1D adrenergic receptor in CHO-cells (chinese hamster ovary cells) | J Med Chem 46: 3762-5 (2003) Article DOI: 10.1021/jm030825u BindingDB Entry DOI: 10.7270/Q2BZ65FJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50143691 (8-{2-[4-(2,5-Dichloro-phenyl)-piperidin-1-yl]-ethy...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description Binding affinity to the adrenergic receptor alpha-1D of rat aorta | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1B adrenergic receptor (Homo sapiens (Human)) | BDBM50073563 (1-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piper...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.57 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati S.p.A. Curated by ChEMBL | Assay Description The binding affinity of the compound was determined towards Alpha-1B adrenergic receptor in the COS cell line. | J Med Chem 42: 427-37 (1999) Article DOI: 10.1021/jm9805337 BindingDB Entry DOI: 10.7270/Q2FN15CK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A adrenergic receptor (Homo sapiens (Human)) | BDBM50073563 (1-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piper...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.59 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati S.p.A. Curated by ChEMBL | Assay Description The binding affinity of the compound was determined towards Alpha-1C adrenergic receptor in the COS cell line. | J Med Chem 42: 427-37 (1999) Article DOI: 10.1021/jm9805337 BindingDB Entry DOI: 10.7270/Q2FN15CK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50143693 (8-{2-[4-(2-Bromo-phenyl)-piperazin-1-yl]-ethyl}-8-...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description Binding affinity to the adrenergic receptor alpha-1D of rat aorta | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50131889 (3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic a...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università degli Studi di Torino Curated by ChEMBL | Assay Description Inhibition of [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor serotonergic receptor in human HeLa cells | J Med Chem 46: 3762-5 (2003) Article DOI: 10.1021/jm030825u BindingDB Entry DOI: 10.7270/Q2BZ65FJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50143682 (8-{3-[4-(2,5-Dichloro-phenyl)-piperazin-1-yl]-prop...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.72 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description Binding affinity to the adrenergic receptor alpha-1D of rat aorta | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A adrenergic receptor (Homo sapiens (Human)) | BDBM50131888 (4-[2-(4-{3-[(3-Methyl-4-oxo-2-phenyl-4H-chromene-8...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università degli Studi di Torino Curated by ChEMBL | Assay Description Inhibition of [3H]-prazosin binding to cloned human Alpha-1A adrenergic receptor in CHO-cells (chinese hamster ovary cells) | J Med Chem 46: 3762-5 (2003) Article DOI: 10.1021/jm030825u BindingDB Entry DOI: 10.7270/Q2BZ65FJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50143703 (8-{4-[4-(2,5-Dichloro-phenyl)-piperazin-1-yl]-buty...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.81 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description In vitro binding affinity towards alpha-1A adrenergic receptor through displacement of [3H]-prazosin in epididymal rat vas deferens. | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50143652 (8-{2-[4-(2-Chloro-phenyl)-piperidin-1-yl]-ethyl}-8...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.01 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description In vitro binding affinity towards alpha-1A adrenergic receptor through displacement of [3H]-prazosin in epididymal rat vas deferens. | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50026941 (8-{2-[4-(3-Chloro-phenyl)-piperazin-1-yl]-ethyl}-8...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.02 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description Binding affinity to the adrenergic receptor alpha-1D of rat aorta | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50143715 (8-[2-(4-o-Tolyl-piperazin-1-yl)-ethyl]-8-aza-spiro...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati s.p.a. Curated by ChEMBL | Assay Description Binding affinity to the adrenergic receptor alpha-1D of rat aorta | J Med Chem 47: 1900-18 (2004) Article DOI: 10.1021/jm030944+ BindingDB Entry DOI: 10.7270/Q23F4P35 | |||||||||||
More data for this Ligand-Target Pair |
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