BindingDB PrimarySearch

Found 1722 hits with Last Name = 'qi' and Initial = 'n'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50188619 (1-(2-(p-toluidino)-5-nitrophenylsulfonyl)-3-tert-b...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li&eagrove;ge Curated by PDSP K_i Database									J Pharmacol Exp Ther 313: 293-301 (2005) Article DOI: 10.1124/jpet.104.079301 BindingDB Entry DOI: 10.7270/Q2NV9GVJ
University of Li&eagrove;ge Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50188619 (1-(2-(p-toluidino)-5-nitrophenylsulfonyl)-3-tert-b...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li&eagrove;ge Curated by PDSP K_i Database									J Pharmacol Exp Ther 313: 293-301 (2005) Article DOI: 10.1124/jpet.104.079301 BindingDB Entry DOI: 10.7270/Q2NV9GVJ
University of Li&eagrove;ge Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50188619 (1-(2-(p-toluidino)-5-nitrophenylsulfonyl)-3-tert-b...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li&eagrove;ge Curated by PDSP K_i Database									J Pharmacol Exp Ther 313: 293-301 (2005) Article DOI: 10.1124/jpet.104.079301 BindingDB Entry DOI: 10.7270/Q2NV9GVJ
University of Li&eagrove;ge Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50167939 (3,4-DNH \| 5-Hydroxy Tryptamine \| BM 613 \| Benzen \|...) Show SMILES c1ccccc1 Show InChI InChI=1S/C6H6/c1-2-4-6-5-3-1/h1-6H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li&eagrove;ge Curated by PDSP K_i Database									J Pharmacol Exp Ther 313: 293-301 (2005) Article DOI: 10.1124/jpet.104.079301 BindingDB Entry DOI: 10.7270/Q2NV9GVJ
University of Li&eagrove;ge Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50167939 (3,4-DNH \| 5-Hydroxy Tryptamine \| BM 613 \| Benzen \|...) Show SMILES c1ccccc1 Show InChI InChI=1S/C6H6/c1-2-4-6-5-3-1/h1-6H	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li&eagrove;ge Curated by PDSP K_i Database									J Pharmacol Exp Ther 313: 293-301 (2005) Article DOI: 10.1124/jpet.104.079301 BindingDB Entry DOI: 10.7270/Q2NV9GVJ
University of Li&eagrove;ge Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50167939 (3,4-DNH \| 5-Hydroxy Tryptamine \| BM 613 \| Benzen \|...) Show SMILES c1ccccc1 Show InChI InChI=1S/C6H6/c1-2-4-6-5-3-1/h1-6H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li&eagrove;ge Curated by PDSP K_i Database									J Pharmacol Exp Ther 313: 293-301 (2005) Article DOI: 10.1124/jpet.104.079301 BindingDB Entry DOI: 10.7270/Q2NV9GVJ
University of Li&eagrove;ge Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50086717 (JNJ-39439335 \| Mavatrep) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	6.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-RTX from human TRPV1 transfected in HEK293 cells after 60 mins by scintillation spectroscopic analysis				J Med Chem 58: 3859-74 (2015) Article DOI: 10.1021/acs.jmedchem.5b00132 BindingDB Entry DOI: 10.7270/Q2154JS3
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM86670 (CAS_98299-61-7 \| NSC_104927 \| SQ 29548) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li&eagrove;ge Curated by PDSP K_i Database									J Pharmacol Exp Ther 313: 293-301 (2005) Article DOI: 10.1124/jpet.104.079301 BindingDB Entry DOI: 10.7270/Q2NV9GVJ
University of Li&eagrove;ge Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Fatty acid-binding protein, adipocyte (Rattus norvegicus)	BDBM50212873 (((2'-(5-ETHYL-3,4-DIPHENYL-1H-PYRAZOL-1-YL)-3-BIPH...) Show SMILES Show InChI	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	PDB Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of rat ap2 by fluorescent 1,8-anilino-8-naphthalene sulfonate assay				Eur J Med Chem 52: 70-81 (2012) Article DOI: 10.1016/j.ejmech.2012.03.006 BindingDB Entry DOI: 10.7270/Q26H4JD5
Sichuan University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Fatty acid-binding protein, adipocyte (Rattus norvegicus)	BDBM50381857 (CHEMBL2023268) Show SMILES OC(=O)\C=C\c1cn(Cc2ccccc2F)c2ccccc12 Show InChI	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of rat ap2 by fluorescent 1,8-anilino-8-naphthalene sulfonate assay				Eur J Med Chem 52: 70-81 (2012) Article DOI: 10.1016/j.ejmech.2012.03.006 BindingDB Entry DOI: 10.7270/Q26H4JD5
Sichuan University Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM10887 (Sulfamate 7 \| Topiramate (TPM) \| US11535599, Examp...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 by ThermoFluor method				J Med Chem 52: 7528-36 (2009) Article DOI: 10.1021/jm801432r BindingDB Entry DOI: 10.7270/Q21J9BQD
					More data for this Ligand-Target Pair				3D Structure (crystal)
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50167939 (3,4-DNH \| 5-Hydroxy Tryptamine \| BM 613 \| Benzen \|...) Show SMILES c1ccccc1 Show InChI InChI=1S/C6H6/c1-2-4-6-5-3-1/h1-6H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li&eagrove;ge Curated by PDSP K_i Database									J Pharmacol Exp Ther 313: 293-301 (2005) Article DOI: 10.1124/jpet.104.079301 BindingDB Entry DOI: 10.7270/Q2NV9GVJ
University of Li&eagrove;ge Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50587720 (CHEMBL5195946) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01782 BindingDB Entry DOI: 10.7270/Q2G73JP3
TBA					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM248583 (US9434711, 496) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.183	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica, N.V. US Patent					Assay Description For patch clamp experiments, HEK293 cells are stably transfected with canine TRPM8 and cultured in DMEM supplemented with 10% fetal bovine serum, 100...				US Patent US9434711 (2016) BindingDB Entry DOI: 10.7270/Q2H41QB6
Janssen Pharmaceutica, N.V. US Patent					More data for this Ligand-Target Pair
Hormone-sensitive lipase (Homo sapiens (Human))	BDBM50147315 (2-(4-(3-fluorophenyl)piperidine-1-carbonyl)-4-(2-m...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Inhibition of human recombinant hormone sensitive lipase (HSL)				Bioorg Med Chem Lett 14: 3155-9 (2004) Article DOI: 10.1016/j.bmcl.2004.04.015 BindingDB Entry DOI: 10.7270/Q2NV9HQ5
Bayer Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50335165 (3-[2-(1-Oxa-2-aza-spiro[4.5]dec-2-en-3-yl)-6-(2-tr...) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research and Development Curated by ChEMBL					Assay Description Antagonist activity at canine TRPM8 expressed in HEK293 cells assessed as inhibition of intracellular calcium accumulation by FLIPR assay				J Med Chem 54: 233-47 (2011) Article DOI: 10.1021/jm101075v BindingDB Entry DOI: 10.7270/Q20C4WRJ
Janssen Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50040437 (CHEMBL3360608) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.260	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assay				Bioorg Med Chem 22: 6796-805 (2015) Article DOI: 10.1016/j.bmc.2014.10.038 BindingDB Entry DOI: 10.7270/Q22J6DHQ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50040432 (CHEMBL3360603) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.310	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assay				Bioorg Med Chem 22: 6796-805 (2015) Article DOI: 10.1016/j.bmc.2014.10.038 BindingDB Entry DOI: 10.7270/Q22J6DHQ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	0.310	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin) by mobility shift assay				Eur J Med Chem 117: 47-58 (2016) Article DOI: 10.1016/j.ejmech.2016.03.074 BindingDB Entry DOI: 10.7270/Q2QJ7K5K
Zhejiang University Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50039330 (CHEMBL3355877) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.320	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assay				Eur J Med Chem 89: 826-34 (2014) Article DOI: 10.1016/j.ejmech.2014.11.010 BindingDB Entry DOI: 10.7270/Q24F1SC5
Zhejiang University Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50040435 (CHEMBL3360606) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.320	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assay				Bioorg Med Chem 22: 6796-805 (2015) Article DOI: 10.1016/j.bmc.2014.10.038 BindingDB Entry DOI: 10.7270/Q22J6DHQ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50040449 (CHEMBL3360619) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.330	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assay				Bioorg Med Chem 22: 6796-805 (2015) Article DOI: 10.1016/j.bmc.2014.10.038 BindingDB Entry DOI: 10.7270/Q22J6DHQ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Testis-specific serine/threonine-protein kinase 1 (Mus musculus)	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	0.330	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of mouse TSSK1 by luminescent ADP-Glo assay kit				Eur J Med Chem 117: 47-58 (2016) Article DOI: 10.1016/j.ejmech.2016.03.074 BindingDB Entry DOI: 10.7270/Q2QJ7K5K
Zhejiang University Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50040448 (CHEMBL3360618) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.370	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assay				Bioorg Med Chem 22: 6796-805 (2015) Article DOI: 10.1016/j.bmc.2014.10.038 BindingDB Entry DOI: 10.7270/Q22J6DHQ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50587716 (CHEMBL5188297) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01782 BindingDB Entry DOI: 10.7270/Q2G73JP3
TBA					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50036555 (CHEMBL3353610 \| US9434711, 497) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	37
Janssen Pharmaceutica, N.V. US Patent					Assay Description The functional activity of compounds of the formula (I) was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensi...				US Patent US9434711 (2016) BindingDB Entry DOI: 10.7270/Q2H41QB6
Janssen Pharmaceutica, N.V. US Patent					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50335157 (3-[7-Trifluoromethyl-5-(2-trifluoromethyl-phenyl)-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	0.413	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research and Development Curated by ChEMBL					Assay Description Inhibition of human TRPM8 expressed in HEK293 cells assessed as inhibition of cold-induced channel current by whole cell electrophysiology				J Med Chem 54: 233-47 (2011) Article DOI: 10.1021/jm101075v BindingDB Entry DOI: 10.7270/Q20C4WRJ
Janssen Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM5447 (CHEMBL939 \| GEFITINIB \| Iressa \| N-(3-Chloro-4-flu...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	0.450	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assay				Eur J Med Chem 89: 826-34 (2014) Article DOI: 10.1016/j.ejmech.2014.11.010 BindingDB Entry DOI: 10.7270/Q24F1SC5
Zhejiang University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM5447 (CHEMBL939 \| GEFITINIB \| Iressa \| N-(3-Chloro-4-flu...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	0.450	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assay				Bioorg Med Chem 22: 6796-805 (2015) Article DOI: 10.1016/j.bmc.2014.10.038 BindingDB Entry DOI: 10.7270/Q22J6DHQ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50188618 (CHEMBL209168 \| N-[2-(4-methylphenylamino)-5-nitrob...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.460	n/a	n/a	n/a	n/a	n/a	n/a
University of Liège Curated by ChEMBL					Assay Description Displacement of [3H]SQ29,548 from TPalpha receptor (short isoform) expressed in COS7 cells at 1 uM				J Med Chem 49: 3701-9 (2006) Article DOI: 10.1021/jm060108a BindingDB Entry DOI: 10.7270/Q2X63MJT
University of Liège Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50039328 (CHEMBL3355875) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.470	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assay				Eur J Med Chem 89: 826-34 (2014) Article DOI: 10.1016/j.ejmech.2014.11.010 BindingDB Entry DOI: 10.7270/Q24F1SC5
Zhejiang University Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50040438 (CHEMBL3360609) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.470	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assay				Bioorg Med Chem 22: 6796-805 (2015) Article DOI: 10.1016/j.bmc.2014.10.038 BindingDB Entry DOI: 10.7270/Q22J6DHQ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50039334 (CHEMBL3355881) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.490	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assay				Eur J Med Chem 89: 826-34 (2014) Article DOI: 10.1016/j.ejmech.2014.11.010 BindingDB Entry DOI: 10.7270/Q24F1SC5
Zhejiang University Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50040447 (CHEMBL3360617) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.490	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assay				Bioorg Med Chem 22: 6796-805 (2015) Article DOI: 10.1016/j.bmc.2014.10.038 BindingDB Entry DOI: 10.7270/Q22J6DHQ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50039335 (CHEMBL3355882) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assay				Eur J Med Chem 89: 826-34 (2014) Article DOI: 10.1016/j.ejmech.2014.11.010 BindingDB Entry DOI: 10.7270/Q24F1SC5
Zhejiang University Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50039329 (CHEMBL3355876) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.510	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assay				Eur J Med Chem 89: 826-34 (2014) Article DOI: 10.1016/j.ejmech.2014.11.010 BindingDB Entry DOI: 10.7270/Q24F1SC5
Zhejiang University Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50040433 (CHEMBL3360604) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.520	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assay				Bioorg Med Chem 22: 6796-805 (2015) Article DOI: 10.1016/j.bmc.2014.10.038 BindingDB Entry DOI: 10.7270/Q22J6DHQ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50039459 (CHEMBL3355889) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.530	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assay				Eur J Med Chem 89: 826-34 (2014) Article DOI: 10.1016/j.ejmech.2014.11.010 BindingDB Entry DOI: 10.7270/Q24F1SC5
Zhejiang University Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50040441 (CHEMBL3360611) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.540	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assay				Bioorg Med Chem 22: 6796-805 (2015) Article DOI: 10.1016/j.bmc.2014.10.038 BindingDB Entry DOI: 10.7270/Q22J6DHQ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM248583 (US9434711, 496) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.554	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica, N.V. US Patent					Assay Description For patch clamp experiments, HEK293 cells are stably transfected with canine TRPM8 and cultured in DMEM supplemented with 10% fetal bovine serum, 100...				US Patent US9434711 (2016) BindingDB Entry DOI: 10.7270/Q2H41QB6
Janssen Pharmaceutica, N.V. US Patent					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50188608 (CHEMBL209306 \| N-tert-butyl-N'-[2-(2,6-dimethylphe...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.560	n/a	n/a	n/a	n/a	n/a	n/a
University of Liège Curated by ChEMBL					Assay Description Displacement of [3H]SQ29,548 from TPbeta receptor (long isoform) expressed in COS7 cells at 1 uM				J Med Chem 49: 3701-9 (2006) Article DOI: 10.1021/jm060108a BindingDB Entry DOI: 10.7270/Q2X63MJT
University of Liège Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50039333 (CHEMBL3355880) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.560	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assay				Eur J Med Chem 89: 826-34 (2014) Article DOI: 10.1016/j.ejmech.2014.11.010 BindingDB Entry DOI: 10.7270/Q24F1SC5
Zhejiang University Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50040440 (CHEMBL3360610) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.570	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assay				Bioorg Med Chem 22: 6796-805 (2015) Article DOI: 10.1016/j.bmc.2014.10.038 BindingDB Entry DOI: 10.7270/Q22J6DHQ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50188613 (CHEMBL209134 \| N-n-pentyl-N'-[2-(3-methyl-4-bromop...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.580	n/a	n/a	n/a	n/a	n/a	n/a
University of Liège Curated by ChEMBL					Assay Description Displacement of [3H]SQ29,548 from TPbeta receptor (long isoform) expressed in COS7 cells at 1 uM				J Med Chem 49: 3701-9 (2006) Article DOI: 10.1021/jm060108a BindingDB Entry DOI: 10.7270/Q2X63MJT
University of Liège Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM248576 (US9434711, 489) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	37
Janssen Pharmaceutica, N.V. US Patent					Assay Description The functional activity of compounds of the formula (I) was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensi...				US Patent US9434711 (2016) BindingDB Entry DOI: 10.7270/Q2H41QB6
Janssen Pharmaceutica, N.V. US Patent					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM248370 (US9434711, 227) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	37
Janssen Pharmaceutica, N.V. US Patent					Assay Description The functional activity of compounds of the formula (I) was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensi...				US Patent US9434711 (2016) BindingDB Entry DOI: 10.7270/Q2H41QB6
Janssen Pharmaceutica, N.V. US Patent					More data for this Ligand-Target Pair
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM50335170 (3-[5-(2-Fluoro-6-trifluoromethylphenyl)-1H-benzimi...) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research and Development Curated by ChEMBL					Assay Description Antagonist activity at canine TRPM8 expressed in HEK293 cells assessed as inhibition of intracellular calcium accumulation by FLIPR assay				J Med Chem 54: 233-47 (2011) Article DOI: 10.1021/jm101075v BindingDB Entry DOI: 10.7270/Q20C4WRJ
Janssen Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50040436 (CHEMBL3360607) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.650	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assay				Bioorg Med Chem 22: 6796-805 (2015) Article DOI: 10.1016/j.bmc.2014.10.038 BindingDB Entry DOI: 10.7270/Q22J6DHQ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50188615 (CHEMBL274415 \| N-n-pentyl-N'-[2-(4-methylphenoxy)-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.650	n/a	n/a	n/a	n/a	n/a	n/a
University of Liège Curated by ChEMBL					Assay Description Displacement of [3H]SQ29,548 from TPbeta receptor (long isoform) expressed in COS7 cells at 1 uM				J Med Chem 49: 3701-9 (2006) Article DOI: 10.1021/jm060108a BindingDB Entry DOI: 10.7270/Q2X63MJT
University of Liège Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50039331 (CHEMBL3355878) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.660	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assay				Eur J Med Chem 89: 826-34 (2014) Article DOI: 10.1016/j.ejmech.2014.11.010 BindingDB Entry DOI: 10.7270/Q24F1SC5
Zhejiang University Curated by ChEMBL					More data for this Ligand-Target Pair

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