Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Renin (Homo sapiens (Human)) | BDBM50012922 (4-Methyl-2-[(pyridin-2-ylmethyl)-amino]-pentanoic ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals Curated by ChEMBL | Assay Description Tested in vitro for their ability to inhibit human renin incubated with human angiotensinogen | J Med Chem 33: 2326-34 (1990) BindingDB Entry DOI: 10.7270/Q2H13105 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Renin (Homo sapiens (Human)) | BDBM50012922 (4-Methyl-2-[(pyridin-2-ylmethyl)-amino]-pentanoic ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals Curated by ChEMBL | Assay Description Tested in vitro for their ability to inhibit human renin incubated with human angiotensinogen | J Med Chem 33: 2326-34 (1990) BindingDB Entry DOI: 10.7270/Q2H13105 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Renin (Homo sapiens (Human)) | BDBM50012928 (2-(3-Aminomethyl-benzylamino)-4-methyl-pentanoic a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals Curated by ChEMBL | Assay Description Tested in vitro for their ability to inhibit human renin incubated with human angiotensinogen | J Med Chem 33: 2326-34 (1990) BindingDB Entry DOI: 10.7270/Q2H13105 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Renin (Homo sapiens (Human)) | BDBM50012923 (2-(3-Aminomethyl-benzylamino)-4-methyl-pentanoic a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals Curated by ChEMBL | Assay Description Tested in vitro for their ability to inhibit human renin incubated with human angiotensinogen | J Med Chem 33: 2326-34 (1990) BindingDB Entry DOI: 10.7270/Q2H13105 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Renin (Homo sapiens (Human)) | BDBM50012923 (2-(3-Aminomethyl-benzylamino)-4-methyl-pentanoic a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals Curated by ChEMBL | Assay Description Tested in vitro for their ability to inhibit human renin incubated with human angiotensinogen | J Med Chem 33: 2326-34 (1990) BindingDB Entry DOI: 10.7270/Q2H13105 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Renin (Homo sapiens (Human)) | BDBM50012932 (4-(1-{1-Cyclohexylmethyl-2-hydroxy-4-[2-(8-isobuty...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals Curated by ChEMBL | Assay Description Tested in vitro for their ability to inhibit human renin incubated with human angiotensinogen | J Med Chem 33: 2326-34 (1990) BindingDB Entry DOI: 10.7270/Q2H13105 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Renin (Homo sapiens (Human)) | BDBM50012925 (2-Amino-6-(1-{1-cyclohexylmethyl-2-hydroxy-4-[2-(8...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals Curated by ChEMBL | Assay Description Tested in vitro for their ability to inhibit human renin incubated with human angiotensinogen | J Med Chem 33: 2326-34 (1990) BindingDB Entry DOI: 10.7270/Q2H13105 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Cavia porcellus) | BDBM50047133 (CHEMBL434768 | {6-Ethyl-2-methyl-4-[2'-(1H-tetrazo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-Angiotensin binding to a guinea pig adrenal membrane preparation which corresponds to Angiotensin II receptor, type 1 | J Med Chem 36: 1245-54 (1993) BindingDB Entry DOI: 10.7270/Q2GM86CM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Cavia porcellus) | BDBM50047117 (2,6-Diethyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-yl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-Angiotensin binding to a guinea pig adrenal membrane preparation which corresponds to Angiotensin II receptor, type 1 | J Med Chem 36: 1245-54 (1993) BindingDB Entry DOI: 10.7270/Q2GM86CM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Cavia porcellus) | BDBM50047111 (6-Ethyl-2-methyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-Angiotensin binding to a guinea pig adrenal membrane preparation which corresponds to Angiotensin II receptor, type 1 | J Med Chem 36: 1245-54 (1993) BindingDB Entry DOI: 10.7270/Q2GM86CM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Cavia porcellus) | BDBM50047113 (2,6-Dimethyl-3-phenyl-4-[2'-(1H-tetrazol-5-yl)-bip...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-Angiotensin binding to a guinea pig adrenal membrane preparation which corresponds to Angiotensin II receptor, type 1 | J Med Chem 36: 1245-54 (1993) BindingDB Entry DOI: 10.7270/Q2GM86CM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Cavia porcellus) | BDBM50047130 (CHEMBL280189 | {2,6-Dimethyl-4-[2'-(1H-tetrazol-5-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-Angiotensin binding to a guinea pig adrenal membrane preparation which corresponds to Angiotensin II receptor, type 1 | J Med Chem 36: 1245-54 (1993) BindingDB Entry DOI: 10.7270/Q2GM86CM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Cavia porcellus) | BDBM50047129 (2-Ethyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmeth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-Angiotensin binding to a guinea pig adrenal membrane preparation which corresponds to Angiotensin II receptor, type 1 | J Med Chem 36: 1245-54 (1993) BindingDB Entry DOI: 10.7270/Q2GM86CM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Cavia porcellus) | BDBM50047122 (1-{6-Ethyl-2-methyl-4-[2'-(1H-tetrazol-5-yl)-biphe...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-Angiotensin binding to a guinea pig adrenal membrane preparation which corresponds to Angiotensin II receptor, type 1 | J Med Chem 36: 1245-54 (1993) BindingDB Entry DOI: 10.7270/Q2GM86CM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Cavia porcellus) | BDBM50047112 (2-Methyl-6-propyl-4-[2'-(1H-tetrazol-5-yl)-bipheny...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-Angiotensin binding to a guinea pig adrenal membrane preparation which corresponds to Angiotensin II receptor, type 1 | J Med Chem 36: 1245-54 (1993) BindingDB Entry DOI: 10.7270/Q2GM86CM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Cavia porcellus) | BDBM50047119 (3-Benzyl-2,6-dimethyl-4-[2'-(1H-tetrazol-5-yl)-bip...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-Angiotensin binding to a guinea pig adrenal membrane preparation which corresponds to Angiotensin II receptor, type 1 | J Med Chem 36: 1245-54 (1993) BindingDB Entry DOI: 10.7270/Q2GM86CM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Cavia porcellus) | BDBM50047132 (2,6-Diethyl-3-iodo-4-[2'-(2H-tetrazol-5-yl)-biphen...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-Angiotensin binding to a guinea pig adrenal membrane preparation which corresponds to Angiotensin II receptor, type 1 | J Med Chem 36: 1245-54 (1993) BindingDB Entry DOI: 10.7270/Q2GM86CM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Cavia porcellus) | BDBM50003392 (2-Methyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-Angiotensin binding to a guinea pig adrenal membrane preparation which corresponds to Angiotensin II receptor, type 1 | J Med Chem 36: 1245-54 (1993) BindingDB Entry DOI: 10.7270/Q2GM86CM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Cavia porcellus) | BDBM50009714 (CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-Angiotensin binding to a guinea pig adrenal membrane preparation which corresponds to Angiotensin II receptor, type 1 | J Med Chem 36: 1245-54 (1993) BindingDB Entry DOI: 10.7270/Q2GM86CM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Cavia porcellus) | BDBM50047125 (2-Ethyl-6-methyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-Angiotensin binding to a guinea pig adrenal membrane preparation which corresponds to Angiotensin II receptor, type 1 | J Med Chem 36: 1245-54 (1993) BindingDB Entry DOI: 10.7270/Q2GM86CM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Cavia porcellus) | BDBM50047127 (2-Ethyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmeth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-Angiotensin binding to a guinea pig adrenal membrane preparation which corresponds to Angiotensin II receptor, type 1 | J Med Chem 36: 1245-54 (1993) BindingDB Entry DOI: 10.7270/Q2GM86CM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Cavia porcellus) | BDBM50047115 (2,6-Dimethyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-y...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-Angiotensin binding to a guinea pig adrenal membrane preparation which corresponds to Angiotensin II receptor, type 1 | J Med Chem 36: 1245-54 (1993) BindingDB Entry DOI: 10.7270/Q2GM86CM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Cavia porcellus) | BDBM50047131 (1-{2,6-Dimethyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-Angiotensin binding to a guinea pig adrenal membrane preparation which corresponds to Angiotensin II receptor, type 1 | J Med Chem 36: 1245-54 (1993) BindingDB Entry DOI: 10.7270/Q2GM86CM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Cavia porcellus) | BDBM50003387 (2-Ethyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmeth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-Angiotensin binding to a guinea pig adrenal membrane preparation which corresponds to Angiotensin II receptor, type 1 | J Med Chem 36: 1245-54 (1993) BindingDB Entry DOI: 10.7270/Q2GM86CM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Cavia porcellus) | BDBM50047118 (3-Iodo-2,6-dimethyl-4-[2'-(1H-tetrazol-5-yl)-biphe...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-Angiotensin binding to a guinea pig adrenal membrane preparation which corresponds to Angiotensin II receptor, type 1 | J Med Chem 36: 1245-54 (1993) BindingDB Entry DOI: 10.7270/Q2GM86CM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Renin (Homo sapiens (Human)) | BDBM50012935 (CHEMBL431401 | N-(2-Cyclohexyl-1-cyclohexylmethyl-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals Curated by ChEMBL | Assay Description Tested in vitro for their ability to inhibit human renin incubated with human angiotensinogen | J Med Chem 33: 2326-34 (1990) BindingDB Entry DOI: 10.7270/Q2H13105 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Cavia porcellus) | BDBM50047126 (2-Ethyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmeth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-Angiotensin binding to a guinea pig adrenal membrane preparation which corresponds to Angiotensin II receptor, type 1 | J Med Chem 36: 1245-54 (1993) BindingDB Entry DOI: 10.7270/Q2GM86CM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Cavia porcellus) | BDBM50047124 (2,6-Dimethyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-y...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-Angiotensin binding to a guinea pig adrenal membrane preparation which corresponds to Angiotensin II receptor, type 1 | J Med Chem 36: 1245-54 (1993) BindingDB Entry DOI: 10.7270/Q2GM86CM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Cavia porcellus) | BDBM50047121 (6-Methyl-2-propyl-4-[2'-(1H-tetrazol-5-yl)-bipheny...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-Angiotensin binding to a guinea pig adrenal membrane preparation which corresponds to Angiotensin II receptor, type 1 | J Med Chem 36: 1245-54 (1993) BindingDB Entry DOI: 10.7270/Q2GM86CM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Renin (Homo sapiens (Human)) | BDBM50012933 (4-Methyl-2-[(pyridin-2-ylmethyl)-amino]-pentanoic ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals Curated by ChEMBL | Assay Description Tested in vitro for their ability to inhibit human renin incubated with human angiotensinogen | J Med Chem 33: 2326-34 (1990) BindingDB Entry DOI: 10.7270/Q2H13105 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Cavia porcellus) | BDBM50047114 (3-Methoxymethyl-2,6-dimethyl-4-[2'-(1H-tetrazol-5-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 86 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-Angiotensin binding to a guinea pig adrenal membrane preparation which corresponds to Angiotensin II receptor, type 1 | J Med Chem 36: 1245-54 (1993) BindingDB Entry DOI: 10.7270/Q2GM86CM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1/Type-2 angiotensin II receptor (Homo sapiens (Human)) | BDBM50005340 (2-Butyl-1-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmeth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 96 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals Curated by ChEMBL | Assay Description Concentration required for 50% displacement of the specifically bound [3-[125I]-iodotyrosyl]-angiotensin II from angiotensin II receptor in the membr... | J Med Chem 35: 877-85 (1992) BindingDB Entry DOI: 10.7270/Q23R0W37 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Cavia porcellus) | BDBM50047128 (CHEMBL283372 | {2,6-Dimethyl-4-[2'-(1H-tetrazol-5-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-Angiotensin binding to a guinea pig adrenal membrane preparation which corresponds to Angiotensin II receptor, type 1 | J Med Chem 36: 1245-54 (1993) BindingDB Entry DOI: 10.7270/Q2GM86CM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Renin (Homo sapiens (Human)) | BDBM50012929 (2-(3-Aminomethyl-benzylamino)-4-methyl-pentanoic a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals Curated by ChEMBL | Assay Description Tested in vitro for their ability to inhibit human renin incubated with human angiotensinogen | J Med Chem 33: 2326-34 (1990) BindingDB Entry DOI: 10.7270/Q2H13105 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Cavia porcellus) | BDBM50047116 (2,3,6-Trimethyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-Angiotensin binding to a guinea pig adrenal membrane preparation which corresponds to Angiotensin II receptor, type 1 | J Med Chem 36: 1245-54 (1993) BindingDB Entry DOI: 10.7270/Q2GM86CM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Renin (Homo sapiens (Human)) | BDBM50012929 (2-(3-Aminomethyl-benzylamino)-4-methyl-pentanoic a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals Curated by ChEMBL | Assay Description Tested in vitro for their ability to inhibit human renin incubated with human angiotensinogen | J Med Chem 33: 2326-34 (1990) BindingDB Entry DOI: 10.7270/Q2H13105 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Cavia porcellus) | BDBM50047134 (2,6-Dimethyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-y...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-Angiotensin binding to a guinea pig adrenal membrane preparation which corresponds to Angiotensin II receptor, type 1 | J Med Chem 36: 1245-54 (1993) BindingDB Entry DOI: 10.7270/Q2GM86CM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Renin (Homo sapiens (Human)) | BDBM50012924 (CHEMBL78121 | N-(2-Cyclohexyl-1-cyclohexylmethyl-2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 290 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals Curated by ChEMBL | Assay Description Tested in vitro for their ability to inhibit human renin incubated with human angiotensinogen | J Med Chem 33: 2326-34 (1990) BindingDB Entry DOI: 10.7270/Q2H13105 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Cavia porcellus) | BDBM50047120 (2,6-Dimethyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-y...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-Angiotensin binding to a guinea pig adrenal membrane preparation which corresponds to Angiotensin II receptor, type 1 | J Med Chem 36: 1245-54 (1993) BindingDB Entry DOI: 10.7270/Q2GM86CM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Renin (Homo sapiens (Human)) | BDBM50012934 (CHEMBL307388 | N-(2-Cyclohexyl-1-cyclohexylmethyl-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals Curated by ChEMBL | Assay Description Tested in vitro for their ability to inhibit human renin incubated with human angiotensinogen | J Med Chem 33: 2326-34 (1990) BindingDB Entry DOI: 10.7270/Q2H13105 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1/Type-2 angiotensin II receptor (Homo sapiens (Human)) | BDBM50003399 (4'-(2-Butyl-4-chloro-5-hydroxymethyl-imidazol-1-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 480 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals Curated by ChEMBL | Assay Description Concentration required for 50% displacement of the specifically bound [3-[125I]-iodotyrosyl]-angiotensin II from angiotensin II receptor in the membr... | J Med Chem 35: 877-85 (1992) BindingDB Entry DOI: 10.7270/Q23R0W37 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1/Type-2 angiotensin II receptor (Homo sapiens (Human)) | BDBM50230428 (CHEMBL352376) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 640 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [3-[125I]-iodotyrosyl]-angiotensin II binding to Angiotensin II receptors in the membrane preparations of guinea pig adrenal glands. | J Med Chem 35: 877-85 (1992) BindingDB Entry DOI: 10.7270/Q23R0W37 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1/Type-2 angiotensin II receptor (Homo sapiens (Human)) | BDBM50230436 (CHEMBL424372) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 860 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [3-[125I]-iodotyrosyl]-angiotensin II binding to Angiotensin II receptors in the membrane preparations of guinea pig adrenal glands. | J Med Chem 35: 877-85 (1992) BindingDB Entry DOI: 10.7270/Q23R0W37 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Renin (Homo sapiens (Human)) | BDBM50406416 (CHEMBL2114143) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals Curated by ChEMBL | Assay Description Tested in vitro for their ability to inhibit human renin incubated with human angiotensinogen | J Med Chem 33: 2326-34 (1990) BindingDB Entry DOI: 10.7270/Q2H13105 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Cavia porcellus) | BDBM50047123 (2,6-Dimethyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-y...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.17E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-Angiotensin binding to a guinea pig adrenal membrane preparation which corresponds to Angiotensin II receptor, type 1 | J Med Chem 36: 1245-54 (1993) BindingDB Entry DOI: 10.7270/Q2GM86CM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1/Type-2 angiotensin II receptor (Homo sapiens (Human)) | BDBM50230438 (CHEMBL171530) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [3-[125I]-iodotyrosyl]-angiotensin II binding to Angiotensin II receptors in the membrane preparations of guinea pig adrenal glands. | J Med Chem 35: 877-85 (1992) BindingDB Entry DOI: 10.7270/Q23R0W37 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1/Type-2 angiotensin II receptor (Homo sapiens (Human)) | BDBM50230439 (CHEMBL172344) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [3-[125I]-iodotyrosyl]-angiotensin II binding to Angiotensin II receptors in the membrane preparations of guinea pig adrenal glands. | J Med Chem 35: 877-85 (1992) BindingDB Entry DOI: 10.7270/Q23R0W37 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1/Type-2 angiotensin II receptor (Homo sapiens (Human)) | BDBM50230431 (CHEMBL171456) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [3-[125I]-iodotyrosyl]-angiotensin II binding to Angiotensin II receptors in the membrane preparations of guinea pig adrenal glands. | J Med Chem 35: 877-85 (1992) BindingDB Entry DOI: 10.7270/Q23R0W37 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Renin (Homo sapiens (Human)) | BDBM50012927 (CHEMBL76896 | N-(2-Cyclohexyl-1-cyclohexylmethyl-2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.92E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals Curated by ChEMBL | Assay Description Tested in vitro for their ability to inhibit human renin incubated with human angiotensinogen | J Med Chem 33: 2326-34 (1990) BindingDB Entry DOI: 10.7270/Q2H13105 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1/Type-2 angiotensin II receptor (Homo sapiens (Human)) | BDBM50005347 (4'-((2-butyl-1H-benzo[d]imidazol-1-yl)methyl)biphe...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals Curated by ChEMBL | Assay Description Concentration required for 50% displacement of the specifically bound [3-[125I]-iodotyrosyl]-angiotensin II from angiotensin II receptor in the membr... | J Med Chem 35: 877-85 (1992) BindingDB Entry DOI: 10.7270/Q23R0W37 | |||||||||||
More data for this Ligand-Target Pair |
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