Compile Data Set for Download or QSAR

Found 175 hits with Last Name = 'sabalski' and Initial = 'je'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50091825 (8,9-Dichloro-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,...) Show SMILES Clc1cc2NCC3CNCCN3c2cc1Cl Show InChI InChI=1S/C11H13Cl2N3/c12-8-3-10-11(4-9(8)13)16-2-1-14-5-7(16)6-15-10/h3-4,7,14-15H,1-2,5-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity using [125I]-DOI as radioligand with membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptamine 2C receptor				Bioorg Med Chem Lett 10: 1991-4 (2001) BindingDB Entry DOI: 10.7270/Q2Z89BMP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50091831 ((R)-8,9-Dichloro-2,3,4,4a-tetrahydro-1H,6H-pyrazin...) Show SMILES Clc1cc2NC(=O)[C@H]3CNCCN3c2cc1Cl Show InChI InChI=1S/C11H11Cl2N3O/c12-6-3-8-9(4-7(6)13)16-2-1-14-5-10(16)11(17)15-8/h3-4,10,14H,1-2,5H2,(H,15,17)/t10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity using [3H]-mesulergine as radioligand with receptor membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptami...				Bioorg Med Chem Lett 10: 1991-4 (2001) BindingDB Entry DOI: 10.7270/Q2Z89BMP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50091822 (8,9-Dichloro-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1,...) Show SMILES Clc1cc2NC(=O)C3CNCCN3c2cc1Cl Show InChI InChI=1S/C11H11Cl2N3O/c12-6-3-8-9(4-7(6)13)16-2-1-14-5-10(16)11(17)15-8/h3-4,10,14H,1-2,5H2,(H,15,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity using [125I]-DOI as radioligand with membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptamine 2C receptor				Bioorg Med Chem Lett 10: 1991-4 (2001) BindingDB Entry DOI: 10.7270/Q2Z89BMP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50091829 ((R)-8,9-Dichloro-2,3,4,4a,5,6-hexahydro-1H-pyrazin...) Show SMILES Clc1cc2NC[C@H]3CNCCN3c2cc1Cl Show InChI InChI=1S/C11H13Cl2N3/c12-8-3-10-11(4-9(8)13)16-2-1-14-5-7(16)6-15-10/h3-4,7,14-15H,1-2,5-6H2/t7-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity using [125I]-DOI as radioligand with membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptamine 2C receptor				Bioorg Med Chem Lett 10: 1991-4 (2001) BindingDB Entry DOI: 10.7270/Q2Z89BMP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50091826 ((S)-8,9-Dichloro-2,3,4,4a,5,6-hexahydro-1H-pyrazin...) Show SMILES Clc1cc2NC[C@@H]3CNCCN3c2cc1Cl Show InChI InChI=1S/C11H13Cl2N3/c12-8-3-10-11(4-9(8)13)16-2-1-14-5-7(16)6-15-10/h3-4,7,14-15H,1-2,5-6H2/t7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity using [125I]-DOI as radioligand with membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptamine 2C receptor				Bioorg Med Chem Lett 10: 1991-4 (2001) BindingDB Entry DOI: 10.7270/Q2Z89BMP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50091830 (9-Chloro-8-trifluoromethyl-2,3,4,4a-tetrahydro-1H,...) Show SMILES FC(F)(F)c1cc2NC(=O)C3CNCCN3c2cc1Cl Show InChI InChI=1S/C12H11ClF3N3O/c13-7-4-9-8(3-6(7)12(14,15)16)18-11(20)10-5-17-1-2-19(9)10/h3-4,10,17H,1-2,5H2,(H,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity using [125I]-DOI as radioligand with membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptamine 2C receptor				Bioorg Med Chem Lett 10: 1991-4 (2001) BindingDB Entry DOI: 10.7270/Q2Z89BMP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50145565 (1,2,3,4,8,9,10,11,12,13-decahydrocycloocta[b][1,4]...) Show SMILES C1Cn2c3CCCCCCc3c3cccc(CN1)c23 Show InChI InChI=1S/C17H22N2/c1-2-4-9-16-14(7-3-1)15-8-5-6-13-12-18-10-11-19(16)17(13)15/h5-6,8,18H,1-4,7,9-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonistic binding affinity against human 5-hydroxytryptamine 2C receptor in CHO cells using [125I]- DOI				Bioorg Med Chem Lett 14: 2603-7 (2004) Article DOI: 10.1016/j.bmcl.2004.02.100 BindingDB Entry DOI: 10.7270/Q2QZ29F3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50091834 ((R)-9-Chloro-8-trifluoromethyl-2,3,4,4a,5,6-hexahy...) Show SMILES FC(F)(F)c1cc2NC[C@H]3CNCCN3c2cc1Cl Show InChI InChI=1S/C12H13ClF3N3/c13-9-4-11-10(3-8(9)12(14,15)16)18-6-7-5-17-1-2-19(7)11/h3-4,7,17-18H,1-2,5-6H2/t7-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity using [125I]-DOI as radioligand with membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptamine 2C receptor				Bioorg Med Chem Lett 10: 1991-4 (2001) BindingDB Entry DOI: 10.7270/Q2Z89BMP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50091825 (8,9-Dichloro-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,...) Show SMILES Clc1cc2NCC3CNCCN3c2cc1Cl Show InChI InChI=1S/C11H13Cl2N3/c12-8-3-10-11(4-9(8)13)16-2-1-14-5-7(16)6-15-10/h3-4,7,14-15H,1-2,5-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity using [125I]-DOI as radioligand with membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptamine 2C receptor				Bioorg Med Chem Lett 10: 1991-4 (2001) BindingDB Entry DOI: 10.7270/Q2Z89BMP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50091832 (7,9-Dichloro-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1,...) Show SMILES Clc1cc(Cl)c2NC(=O)C3CNCCN3c2c1 Show InChI InChI=1S/C11H11Cl2N3O/c12-6-3-7(13)10-8(4-6)16-2-1-14-5-9(16)11(17)15-10/h3-4,9,14H,1-2,5H2,(H,15,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Agonistic activity for 5-HT2c (5-HT2C) by measuring [3H]-inositol monophosphate fromation in CHO cells in which the human 5-HT2C receptor subtype was...				Bioorg Med Chem Lett 10: 1991-4 (2001) BindingDB Entry DOI: 10.7270/Q2Z89BMP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50091835 ((R)-9-Chloro-8-trifluoromethyl-2,3,4,4a-tetrahydro...) Show SMILES FC(F)(F)c1cc2NC(=O)[C@H]3CNCCN3c2cc1Cl Show InChI InChI=1S/C12H11ClF3N3O/c13-7-4-9-8(3-6(7)12(14,15)16)18-11(20)10-5-17-1-2-19(9)10/h3-4,10,17H,1-2,5H2,(H,18,20)/t10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity using [125I]-DOI as radioligand with membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptamine 2C receptor				Bioorg Med Chem Lett 10: 1991-4 (2001) BindingDB Entry DOI: 10.7270/Q2Z89BMP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50091831 ((R)-8,9-Dichloro-2,3,4,4a-tetrahydro-1H,6H-pyrazin...) Show SMILES Clc1cc2NC(=O)[C@H]3CNCCN3c2cc1Cl Show InChI InChI=1S/C11H11Cl2N3O/c12-6-3-8-9(4-7(6)13)16-2-1-14-5-10(16)11(17)15-8/h3-4,10,14H,1-2,5H2,(H,15,17)/t10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity using [3H]-mesulergine as radioligand with receptor membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptami...				Bioorg Med Chem Lett 10: 1991-4 (2001) BindingDB Entry DOI: 10.7270/Q2Z89BMP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50091821 ((R)-9-Chloro-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1,...) Show SMILES Clc1ccc2NC(=O)[C@H]3CNCCN3c2c1 Show InChI InChI=1S/C11H12ClN3O/c12-7-1-2-8-9(5-7)15-4-3-13-6-10(15)11(16)14-8/h1-2,5,10,13H,3-4,6H2,(H,14,16)/t10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity using [3H]-mesulergine as radioligand with receptor membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptami...				Bioorg Med Chem Lett 10: 1991-4 (2001) BindingDB Entry DOI: 10.7270/Q2Z89BMP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50145565 (1,2,3,4,8,9,10,11,12,13-decahydrocycloocta[b][1,4]...) Show SMILES C1Cn2c3CCCCCCc3c3cccc(CN1)c23 Show InChI InChI=1S/C17H22N2/c1-2-4-9-16-14(7-3-1)15-8-5-6-13-12-18-10-11-19(16)17(13)15/h5-6,8,18H,1-4,7,9-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonistic binding affinity of the compound against human 5-hydroxytryptamine 2A receptor in CHO cells using 8-OH-DPA radioligand				Bioorg Med Chem Lett 14: 2603-7 (2004) Article DOI: 10.1016/j.bmcl.2004.02.100 BindingDB Entry DOI: 10.7270/Q2QZ29F3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50145564 (4,5,6,7,9,10,11,12-Octahydro-8H-5,7a-diaza-benzo[c...) Show SMILES C1CCc2c(CC1)c1cccc3CNCCn2c13 Show InChI InChI=1S/C16H20N2/c1-2-6-13-14-7-4-5-12-11-17-9-10-18(16(12)14)15(13)8-3-1/h4-5,7,17H,1-3,6,8-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonistic binding affinity against human 5-hydroxytryptamine 2C receptor in CHO cells using [125I]- DOI				Bioorg Med Chem Lett 14: 2603-7 (2004) Article DOI: 10.1016/j.bmcl.2004.02.100 BindingDB Entry DOI: 10.7270/Q2QZ29F3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50091822 (8,9-Dichloro-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1,...) Show SMILES Clc1cc2NC(=O)C3CNCCN3c2cc1Cl Show InChI InChI=1S/C11H11Cl2N3O/c12-6-3-8-9(4-7(6)13)16-2-1-14-5-10(16)11(17)15-8/h3-4,10,14H,1-2,5H2,(H,15,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity using [3H]-mesulergine as radioligand with receptor membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptami...				Bioorg Med Chem Lett 10: 1991-4 (2001) BindingDB Entry DOI: 10.7270/Q2Z89BMP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50091826 ((S)-8,9-Dichloro-2,3,4,4a,5,6-hexahydro-1H-pyrazin...) Show SMILES Clc1cc2NC[C@@H]3CNCCN3c2cc1Cl Show InChI InChI=1S/C11H13Cl2N3/c12-8-3-10-11(4-9(8)13)16-2-1-14-5-7(16)6-15-10/h3-4,7,14-15H,1-2,5-6H2/t7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	61	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity using [3H]-mesulergine as radioligand with receptor membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptami...				Bioorg Med Chem Lett 10: 1991-4 (2001) BindingDB Entry DOI: 10.7270/Q2Z89BMP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50091827 ((S)-8,9-Dichloro-2,3,4,4a-tetrahydro-1H,6H-pyrazin...) Show SMILES Clc1cc2NC(=O)[C@@H]3CNCCN3c2cc1Cl Show InChI InChI=1S/C11H11Cl2N3O/c12-6-3-8-9(4-7(6)13)16-2-1-14-5-10(16)11(17)15-8/h3-4,10,14H,1-2,5H2,(H,15,17)/t10-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity using [125I]-DOI as radioligand with membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptamine 2C receptor				Bioorg Med Chem Lett 10: 1991-4 (2001) BindingDB Entry DOI: 10.7270/Q2Z89BMP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50145562 (8,8,10,10-Tetramethyl-1,2,3,4,8,9,10,11-octahydro-...) Show SMILES CC1(C)Cc2c(c3cccc4CNCCn2c34)C(C)(C)C1 Show InChI InChI=1S/C19H26N2/c1-18(2)10-15-16(19(3,4)12-18)14-7-5-6-13-11-20-8-9-21(15)17(13)14/h5-7,20H,8-12H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonistic binding affinity against human 5-hydroxytryptamine 2C receptor in CHO cells using [125I]- DOI				Bioorg Med Chem Lett 14: 2603-7 (2004) Article DOI: 10.1016/j.bmcl.2004.02.100 BindingDB Entry DOI: 10.7270/Q2QZ29F3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50091830 (9-Chloro-8-trifluoromethyl-2,3,4,4a-tetrahydro-1H,...) Show SMILES FC(F)(F)c1cc2NC(=O)C3CNCCN3c2cc1Cl Show InChI InChI=1S/C12H11ClF3N3O/c13-7-4-9-8(3-6(7)12(14,15)16)18-11(20)10-5-17-1-2-19(9)10/h3-4,10,17H,1-2,5H2,(H,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	84	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity using [125I]-DOI as radioligand with membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptamine 2C receptor				Bioorg Med Chem Lett 10: 1991-4 (2001) BindingDB Entry DOI: 10.7270/Q2Z89BMP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50091829 ((R)-8,9-Dichloro-2,3,4,4a,5,6-hexahydro-1H-pyrazin...) Show SMILES Clc1cc2NC[C@H]3CNCCN3c2cc1Cl Show InChI InChI=1S/C11H13Cl2N3/c12-8-3-10-11(4-9(8)13)16-2-1-14-5-7(16)6-15-10/h3-4,7,14-15H,1-2,5-6H2/t7-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity using [125I]-DOI as radioligand with membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptamine 2C receptor				Bioorg Med Chem Lett 10: 1991-4 (2001) BindingDB Entry DOI: 10.7270/Q2Z89BMP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50091833 (8,9-Difluoro-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1,...) Show SMILES Fc1cc2NC(=O)C3CNCCN3c2cc1F Show InChI InChI=1S/C11H11F2N3O/c12-6-3-8-9(4-7(6)13)16-2-1-14-5-10(16)11(17)15-8/h3-4,10,14H,1-2,5H2,(H,15,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity using [3H]-mesulergine as radioligand with receptor membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptami...				Bioorg Med Chem Lett 10: 1991-4 (2001) BindingDB Entry DOI: 10.7270/Q2Z89BMP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50091834 ((R)-9-Chloro-8-trifluoromethyl-2,3,4,4a,5,6-hexahy...) Show SMILES FC(F)(F)c1cc2NC[C@H]3CNCCN3c2cc1Cl Show InChI InChI=1S/C12H13ClF3N3/c13-9-4-11-10(3-8(9)12(14,15)16)18-6-7-5-17-1-2-19(7)11/h3-4,7,17-18H,1-2,5-6H2/t7-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	92	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Agonistic activity for 5-HT2c (5-HT2C) by measuring [3H]-inositol monophosphate fromation in CHO cells in which the human 5-HT2C receptor subtype was...				Bioorg Med Chem Lett 10: 1991-4 (2001) BindingDB Entry DOI: 10.7270/Q2Z89BMP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50145568 (4,5,6,7,9,10-Hexahydro-8H-5,7a-diaza-benzo[cd]cycl...) Show SMILES C1Cc2c(C1)c1cccc3CNCCn2c13 Show InChI InChI=1S/C14H16N2/c1-3-10-9-15-7-8-16-13-6-2-4-11(13)12(5-1)14(10)16/h1,3,5,15H,2,4,6-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	97	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonistic binding affinity against human 5-hydroxytryptamine 2C receptor in CHO cells using [125I]- DOI				Bioorg Med Chem Lett 14: 2603-7 (2004) Article DOI: 10.1016/j.bmcl.2004.02.100 BindingDB Entry DOI: 10.7270/Q2QZ29F3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50145569 (7-Fluoro-1,2,3,4,8,9,10,11-octahydro-[1,4]diazepin...) Show SMILES Fc1ccc2CNCCn3c4CCCCc4c1c23 Show InChI InChI=1S/C15H17FN2/c16-12-6-5-10-9-17-7-8-18-13-4-2-1-3-11(13)14(12)15(10)18/h5-6,17H,1-4,7-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	111	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonistic binding affinity against human 5-hydroxytryptamine 2C receptor in CHO cells using [125I]- DOI				Bioorg Med Chem Lett 14: 2603-7 (2004) Article DOI: 10.1016/j.bmcl.2004.02.100 BindingDB Entry DOI: 10.7270/Q2QZ29F3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50145562 (8,8,10,10-Tetramethyl-1,2,3,4,8,9,10,11-octahydro-...) Show SMILES CC1(C)Cc2c(c3cccc4CNCCn2c34)C(C)(C)C1 Show InChI InChI=1S/C19H26N2/c1-18(2)10-15-16(19(3,4)12-18)14-7-5-6-13-11-20-8-9-21(15)17(13)14/h5-7,20H,8-12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	152	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonistic binding affinity of the compound against human 5-hydroxytryptamine 2A receptor in CHO cells using 8-OH-DPA radioligand				Bioorg Med Chem Lett 14: 2603-7 (2004) Article DOI: 10.1016/j.bmcl.2004.02.100 BindingDB Entry DOI: 10.7270/Q2QZ29F3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50091835 ((R)-9-Chloro-8-trifluoromethyl-2,3,4,4a-tetrahydro...) Show SMILES FC(F)(F)c1cc2NC(=O)[C@H]3CNCCN3c2cc1Cl Show InChI InChI=1S/C12H11ClF3N3O/c13-7-4-9-8(3-6(7)12(14,15)16)18-11(20)10-5-17-1-2-19(9)10/h3-4,10,17H,1-2,5H2,(H,18,20)/t10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity using [125I]-DOI as radioligand with membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptamine 2C receptor				Bioorg Med Chem Lett 10: 1991-4 (2001) BindingDB Entry DOI: 10.7270/Q2Z89BMP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50145559 ((R)-2-Methyl-1,2,3,4,8,9,10,11-octahydro-[1,4]diaz...) Show SMILES C[C@@H]1Cn2c3CCCCc3c3cccc(CN1)c23 Show InChI InChI=1S/C16H20N2/c1-11-10-18-15-8-3-2-6-13(15)14-7-4-5-12(9-17-11)16(14)18/h4-5,7,11,17H,2-3,6,8-10H2,1H3/t11-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	189	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonistic binding affinity against human 5-hydroxytryptamine 2C receptor in CHO cells using [125I]- DOI				Bioorg Med Chem Lett 14: 2603-7 (2004) Article DOI: 10.1016/j.bmcl.2004.02.100 BindingDB Entry DOI: 10.7270/Q2QZ29F3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50145564 (4,5,6,7,9,10,11,12-Octahydro-8H-5,7a-diaza-benzo[c...) Show SMILES C1CCc2c(CC1)c1cccc3CNCCn2c13 Show InChI InChI=1S/C16H20N2/c1-2-6-13-14-7-4-5-12-11-17-9-10-18(16(12)14)15(13)8-3-1/h4-5,7,17H,1-3,6,8-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	199	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonistic binding affinity of the compound against human 5-hydroxytryptamine 2A receptor in CHO cells using 8-OH-DPA radioligand				Bioorg Med Chem Lett 14: 2603-7 (2004) Article DOI: 10.1016/j.bmcl.2004.02.100 BindingDB Entry DOI: 10.7270/Q2QZ29F3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50091821 ((R)-9-Chloro-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1,...) Show SMILES Clc1ccc2NC(=O)[C@H]3CNCCN3c2c1 Show InChI InChI=1S/C11H12ClN3O/c12-7-1-2-8-9(5-7)15-4-3-13-6-10(15)11(16)14-8/h1-2,5,10,13H,3-4,6H2,(H,14,16)/t10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	238	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity using [3H]-mesulergine as radioligand with receptor membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptami...				Bioorg Med Chem Lett 10: 1991-4 (2001) BindingDB Entry DOI: 10.7270/Q2Z89BMP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50145563 (9,9-Dimethyl-1,2,3,4,8,9,10,11-octahydro-[1,4]diaz...) Show SMILES CC1(C)CCc2c(C1)c1cccc3CNCCn2c13 Show InChI InChI=1S/C17H22N2/c1-17(2)7-6-15-14(10-17)13-5-3-4-12-11-18-8-9-19(15)16(12)13/h3-5,18H,6-11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	243	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonistic binding affinity against human 5-hydroxytryptamine 2C receptor in CHO cells using [125I]- DOI				Bioorg Med Chem Lett 14: 2603-7 (2004) Article DOI: 10.1016/j.bmcl.2004.02.100 BindingDB Entry DOI: 10.7270/Q2QZ29F3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50091827 ((S)-8,9-Dichloro-2,3,4,4a-tetrahydro-1H,6H-pyrazin...) Show SMILES Clc1cc2NC(=O)[C@@H]3CNCCN3c2cc1Cl Show InChI InChI=1S/C11H11Cl2N3O/c12-6-3-8-9(4-7(6)13)16-2-1-14-5-10(16)11(17)15-8/h3-4,10,14H,1-2,5H2,(H,15,17)/t10-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	285	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Agonistic activity for 5-HT2c (5-HT2C) by measuring [3H]-inositol monophosphate fromation in CHO cells in which the human 5-HT2C receptor subtype was...				Bioorg Med Chem Lett 10: 1991-4 (2001) BindingDB Entry DOI: 10.7270/Q2Z89BMP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50145561 (6-Chloro-1,2,3,4,8,9,10,11-octahydro-[1,4]diazepin...) Show SMILES Clc1cc2CNCCn3c4CCCCc4c(c1)c23 Show InChI InChI=1S/C15H17ClN2/c16-11-7-10-9-17-5-6-18-14-4-2-1-3-12(14)13(8-11)15(10)18/h7-8,17H,1-6,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	358	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonistic binding affinity against human 5-hydroxytryptamine 2C receptor in CHO cells using [125I]- DOI				Bioorg Med Chem Lett 14: 2603-7 (2004) Article DOI: 10.1016/j.bmcl.2004.02.100 BindingDB Entry DOI: 10.7270/Q2QZ29F3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50091832 (7,9-Dichloro-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1,...) Show SMILES Clc1cc(Cl)c2NC(=O)C3CNCCN3c2c1 Show InChI InChI=1S/C11H11Cl2N3O/c12-6-3-7(13)10-8(4-6)16-2-1-14-5-9(16)11(17)15-10/h3-4,9,14H,1-2,5H2,(H,15,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	368	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity using [3H]-mesulergine as radioligand with receptor membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptami...				Bioorg Med Chem Lett 10: 1991-4 (2001) BindingDB Entry DOI: 10.7270/Q2Z89BMP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50145560 ((S)-2-Methyl-1,2,3,4,8,9,10,11-octahydro-[1,4]diaz...) Show SMILES C[C@H]1Cn2c3CCCCc3c3cccc(CN1)c23 Show InChI InChI=1S/C16H20N2/c1-11-10-18-15-8-3-2-6-13(15)14-7-4-5-12(9-17-11)16(14)18/h4-5,7,11,17H,2-3,6,8-10H2,1H3/t11-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	452	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonistic binding affinity against human 5-hydroxytryptamine 2C receptor in CHO cells using [125I]- DOI				Bioorg Med Chem Lett 14: 2603-7 (2004) Article DOI: 10.1016/j.bmcl.2004.02.100 BindingDB Entry DOI: 10.7270/Q2QZ29F3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50091824 ((S)-9-Chloro-8-trifluoromethyl-2,3,4,4a-tetrahydro...) Show SMILES FC(F)(F)c1cc2NC(=O)[C@@H]3CNCCN3c2cc1Cl Show InChI InChI=1S/C12H11ClF3N3O/c13-7-4-9-8(3-6(7)12(14,15)16)18-11(20)10-5-17-1-2-19(9)10/h3-4,10,17H,1-2,5H2,(H,18,20)/t10-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	516	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity using [3H]-mesulergine as radioligand with receptor membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptami...				Bioorg Med Chem Lett 10: 1991-4 (2001) BindingDB Entry DOI: 10.7270/Q2Z89BMP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50145566 (6-Methyl-1,2,3,4,8,9,10,11-octahydro-[1,4]diazepin...) Show SMILES Cc1cc2CNCCn3c4CCCCc4c(c1)c23 Show InChI InChI=1S/C16H20N2/c1-11-8-12-10-17-6-7-18-15-5-3-2-4-13(15)14(9-11)16(12)18/h8-9,17H,2-7,10H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	599	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonistic binding affinity against human 5-hydroxytryptamine 2C receptor in CHO cells using [125I]- DOI				Bioorg Med Chem Lett 14: 2603-7 (2004) Article DOI: 10.1016/j.bmcl.2004.02.100 BindingDB Entry DOI: 10.7270/Q2QZ29F3
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50145565 (1,2,3,4,8,9,10,11,12,13-decahydrocycloocta[b][1,4]...) Show SMILES C1Cn2c3CCCCCCc3c3cccc(CN1)c23 Show InChI InChI=1S/C17H22N2/c1-2-4-9-16-14(7-3-1)15-8-5-6-13-12-18-10-11-19(16)17(13)15/h5-6,8,18H,1-4,7,9-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	665	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Binding affinity of the compound against dopamine receptor D1A				Bioorg Med Chem Lett 14: 2603-7 (2004) Article DOI: 10.1016/j.bmcl.2004.02.100 BindingDB Entry DOI: 10.7270/Q2QZ29F3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50145568 (4,5,6,7,9,10-Hexahydro-8H-5,7a-diaza-benzo[cd]cycl...) Show SMILES C1Cc2c(C1)c1cccc3CNCCn2c13 Show InChI InChI=1S/C14H16N2/c1-3-10-9-15-7-8-16-13-6-2-4-11(13)12(5-1)14(10)16/h1,3,5,15H,2,4,6-9H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	922	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonistic binding affinity of the compound against human 5-hydroxytryptamine 2A receptor in CHO cells using 8-OH-DPA radioligand				Bioorg Med Chem Lett 14: 2603-7 (2004) Article DOI: 10.1016/j.bmcl.2004.02.100 BindingDB Entry DOI: 10.7270/Q2QZ29F3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50145567 (2-Methyl-4,5,6,7,9,10-hexahydro-8H-5,7a-diaza-benz...) Show SMILES Cc1cc2CNCCn3c4CCCc4c(c1)c23 Show InChI InChI=1S/C15H18N2/c1-10-7-11-9-16-5-6-17-14-4-2-3-12(14)13(8-10)15(11)17/h7-8,16H,2-6,9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	985	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonistic binding affinity against human 5-hydroxytryptamine 2C receptor in CHO cells using [125I]- DOI				Bioorg Med Chem Lett 14: 2603-7 (2004) Article DOI: 10.1016/j.bmcl.2004.02.100 BindingDB Entry DOI: 10.7270/Q2QZ29F3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50091828 (9,10-Dichloro-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1...) Show SMILES Clc1ccc2NC(=O)C3CNCCN3c2c1Cl Show InChI InChI=1S/C11H11Cl2N3O/c12-6-1-2-7-10(9(6)13)16-4-3-14-5-8(16)11(17)15-7/h1-2,8,14H,3-5H2,(H,15,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity using [125I]-DOI as radioligand with membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptamine 2C receptor				Bioorg Med Chem Lett 10: 1991-4 (2001) BindingDB Entry DOI: 10.7270/Q2Z89BMP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50145566 (6-Methyl-1,2,3,4,8,9,10,11-octahydro-[1,4]diazepin...) Show SMILES Cc1cc2CNCCn3c4CCCCc4c(c1)c23 Show InChI InChI=1S/C16H20N2/c1-11-8-12-10-17-6-7-18-15-5-3-2-4-13(15)14(9-11)16(12)18/h8-9,17H,2-7,10H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.23E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonistic binding affinity of the compound against human 5-hydroxytryptamine 2A receptor in CHO cells using 8-OH-DPA radioligand				Bioorg Med Chem Lett 14: 2603-7 (2004) Article DOI: 10.1016/j.bmcl.2004.02.100 BindingDB Entry DOI: 10.7270/Q2QZ29F3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50145559 ((R)-2-Methyl-1,2,3,4,8,9,10,11-octahydro-[1,4]diaz...) Show SMILES C[C@@H]1Cn2c3CCCCc3c3cccc(CN1)c23 Show InChI InChI=1S/C16H20N2/c1-11-10-18-15-8-3-2-6-13(15)14-7-4-5-12(9-17-11)16(14)18/h4-5,7,11,17H,2-3,6,8-10H2,1H3/t11-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.56E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonistic binding affinity of the compound against human 5-hydroxytryptamine 2A receptor in CHO cells using 8-OH-DPA radioligand				Bioorg Med Chem Lett 14: 2603-7 (2004) Article DOI: 10.1016/j.bmcl.2004.02.100 BindingDB Entry DOI: 10.7270/Q2QZ29F3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50091828 (9,10-Dichloro-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1...) Show SMILES Clc1ccc2NC(=O)C3CNCCN3c2c1Cl Show InChI InChI=1S/C11H11Cl2N3O/c12-6-1-2-7-10(9(6)13)16-4-3-14-5-8(16)11(17)15-7/h1-2,8,14H,3-5H2,(H,15,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity using [3H]-mesulergine as radioligand with receptor membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptami...				Bioorg Med Chem Lett 10: 1991-4 (2001) BindingDB Entry DOI: 10.7270/Q2Z89BMP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50091833 (8,9-Difluoro-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1,...) Show SMILES Fc1cc2NC(=O)C3CNCCN3c2cc1F Show InChI InChI=1S/C11H11F2N3O/c12-6-3-8-9(4-7(6)13)16-2-1-14-5-10(16)11(17)15-8/h3-4,10,14H,1-2,5H2,(H,15,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity using [3H]-mesulergine as radioligand with receptor membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptami...				Bioorg Med Chem Lett 10: 1991-4 (2001) BindingDB Entry DOI: 10.7270/Q2Z89BMP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50091823 (8-Benzoyl-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1,2-a...) Show SMILES O=C(c1ccccc1)c1ccc2N3CCNCC3C(=O)Nc2c1 Show InChI InChI=1S/C18H17N3O2/c22-17(12-4-2-1-3-5-12)13-6-7-15-14(10-13)20-18(23)16-11-19-8-9-21(15)16/h1-7,10,16,19H,8-9,11H2,(H,20,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	2.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity using [125I]-DOI as radioligand with membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptamine 2C receptor				Bioorg Med Chem Lett 10: 1991-4 (2001) BindingDB Entry DOI: 10.7270/Q2Z89BMP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50145567 (2-Methyl-4,5,6,7,9,10-hexahydro-8H-5,7a-diaza-benz...) Show SMILES Cc1cc2CNCCn3c4CCCc4c(c1)c23 Show InChI InChI=1S/C15H18N2/c1-10-7-11-9-16-5-6-17-14-4-2-3-12(14)13(8-10)15(11)17/h7-8,16H,2-6,9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.53E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonistic binding affinity of the compound against human 5-hydroxytryptamine 2A receptor in CHO cells using 8-OH-DPA radioligand				Bioorg Med Chem Lett 14: 2603-7 (2004) Article DOI: 10.1016/j.bmcl.2004.02.100 BindingDB Entry DOI: 10.7270/Q2QZ29F3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50091824 ((S)-9-Chloro-8-trifluoromethyl-2,3,4,4a-tetrahydro...) Show SMILES FC(F)(F)c1cc2NC(=O)[C@@H]3CNCCN3c2cc1Cl Show InChI InChI=1S/C12H11ClF3N3O/c13-7-4-9-8(3-6(7)12(14,15)16)18-11(20)10-5-17-1-2-19(9)10/h3-4,10,17H,1-2,5H2,(H,18,20)/t10-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity using [3H]-mesulergine as radioligand with receptor membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptami...				Bioorg Med Chem Lett 10: 1991-4 (2001) BindingDB Entry DOI: 10.7270/Q2Z89BMP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50145565 (1,2,3,4,8,9,10,11,12,13-decahydrocycloocta[b][1,4]...) Show SMILES C1Cn2c3CCCCCCc3c3cccc(CN1)c23 Show InChI InChI=1S/C17H22N2/c1-2-4-9-16-14(7-3-1)15-8-5-6-13-12-18-10-11-19(16)17(13)15/h5-6,8,18H,1-4,7,9-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Binding affinity of the compound against 5-hydroxytryptamine 1A receptor				Bioorg Med Chem Lett 14: 2603-7 (2004) Article DOI: 10.1016/j.bmcl.2004.02.100 BindingDB Entry DOI: 10.7270/Q2QZ29F3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50091823 (8-Benzoyl-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1,2-a...) Show SMILES O=C(c1ccccc1)c1ccc2N3CCNCC3C(=O)Nc2c1 Show InChI InChI=1S/C18H17N3O2/c22-17(12-4-2-1-3-5-12)13-6-7-15-14(10-13)20-18(23)16-11-19-8-9-21(15)16/h1-7,10,16,19H,8-9,11H2,(H,20,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity using [3H]-mesulergine as radioligand with receptor membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptami...				Bioorg Med Chem Lett 10: 1991-4 (2001) BindingDB Entry DOI: 10.7270/Q2Z89BMP
					More data for this Ligand-Target Pair

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