Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitogen-activated protein kinase 7 (Homo sapiens (Human)) | BDBM50337137 (2-((2-methoxy-4-(4-(pyrrolidin-1-yl)piperidine-1-c...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysis | ACS Med Chem Lett 2: 195-200 (2011) Article DOI: 10.1021/ml100304b BindingDB Entry DOI: 10.7270/Q2222VSB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 7 (Homo sapiens (Human)) | BDBM50337127 (2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysis | ACS Med Chem Lett 2: 195-200 (2011) Article DOI: 10.1021/ml100304b BindingDB Entry DOI: 10.7270/Q2222VSB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 7 (Homo sapiens (Human)) | BDBM50337139 (11-ethyl-2-((2-methoxy-4-(4-methylpiperazin-1-yl)p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysis | ACS Med Chem Lett 2: 195-200 (2011) Article DOI: 10.1021/ml100304b BindingDB Entry DOI: 10.7270/Q2222VSB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 7 (Homo sapiens (Human)) | BDBM50337141 (11-cyclopentyl-2-((2-methoxy-4-(4-methylpiperazin-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysis | ACS Med Chem Lett 2: 195-200 (2011) Article DOI: 10.1021/ml100304b BindingDB Entry DOI: 10.7270/Q2222VSB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 7 (Homo sapiens (Human)) | BDBM50337131 (2-((2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperid...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysis | ACS Med Chem Lett 2: 195-200 (2011) Article DOI: 10.1021/ml100304b BindingDB Entry DOI: 10.7270/Q2222VSB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 7 (Homo sapiens (Human)) | BDBM50337130 (2-((2-methoxy-4-(piperazin-1-yl)phenyl)amino)-5,11...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysis | ACS Med Chem Lett 2: 195-200 (2011) Article DOI: 10.1021/ml100304b BindingDB Entry DOI: 10.7270/Q2222VSB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 7 (Homo sapiens (Human)) | BDBM50337140 (11-isopropyl-2-((2-methoxy-4-(4-methylpiperazin-1-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysis | ACS Med Chem Lett 2: 195-200 (2011) Article DOI: 10.1021/ml100304b BindingDB Entry DOI: 10.7270/Q2222VSB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 7 (Homo sapiens (Human)) | BDBM50337138 (4-((5,11-dimethyl-6-oxo-6,11-dihydro-5H-benzo[e]py...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysis | ACS Med Chem Lett 2: 195-200 (2011) Article DOI: 10.1021/ml100304b BindingDB Entry DOI: 10.7270/Q2222VSB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 7 (Homo sapiens (Human)) | BDBM50337128 (2-((4-(4-hydroxypiperidin-1-yl)-2-methoxyphenyl)am...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysis | ACS Med Chem Lett 2: 195-200 (2011) Article DOI: 10.1021/ml100304b BindingDB Entry DOI: 10.7270/Q2222VSB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 7 (Homo sapiens (Human)) | BDBM50337134 (2-((2-ethoxy-4-(4-hydroxypiperidin-1-yl)phenyl)ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysis | ACS Med Chem Lett 2: 195-200 (2011) Article DOI: 10.1021/ml100304b BindingDB Entry DOI: 10.7270/Q2222VSB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Mitogen-activated protein kinase 7 (Homo sapiens (Human)) | BDBM50337132 (2-((2-methoxy-4-(1-methylpiperidin-4-yl)phenyl)ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysis | ACS Med Chem Lett 2: 195-200 (2011) Article DOI: 10.1021/ml100304b BindingDB Entry DOI: 10.7270/Q2222VSB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 7 (Homo sapiens (Human)) | BDBM50337129 (2-((2-methoxy-4-morpholinophenyl)amino)-5,11-dimet...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysis | ACS Med Chem Lett 2: 195-200 (2011) Article DOI: 10.1021/ml100304b BindingDB Entry DOI: 10.7270/Q2222VSB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 7 (Homo sapiens (Human)) | BDBM50337133 (5,11-dimethyl-2-((2-methyl-4-(4-methylpiperazin-1-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysis | ACS Med Chem Lett 2: 195-200 (2011) Article DOI: 10.1021/ml100304b BindingDB Entry DOI: 10.7270/Q2222VSB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 7 (Homo sapiens (Human)) | BDBM50337135 (4-((5,11-dimethyl-6-oxo-6,11-dihydro-5H-benzo[e]py...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysis | ACS Med Chem Lett 2: 195-200 (2011) Article DOI: 10.1021/ml100304b BindingDB Entry DOI: 10.7270/Q2222VSB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 7 (Homo sapiens (Human)) | BDBM50337136 (4-((5,11-dimethyl-6-oxo-6,11-dihydro-5H-benzo[e]py...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysis | ACS Med Chem Lett 2: 195-200 (2011) Article DOI: 10.1021/ml100304b BindingDB Entry DOI: 10.7270/Q2222VSB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 7 (Homo sapiens (Human)) | BDBM50337144 (8-chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysis | ACS Med Chem Lett 2: 195-200 (2011) Article DOI: 10.1021/ml100304b BindingDB Entry DOI: 10.7270/Q2222VSB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 7 (Homo sapiens (Human)) | BDBM50337143 (9-fluoro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysis | ACS Med Chem Lett 2: 195-200 (2011) Article DOI: 10.1021/ml100304b BindingDB Entry DOI: 10.7270/Q2222VSB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 7 (Homo sapiens (Human)) | BDBM50337142 (2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysis | ACS Med Chem Lett 2: 195-200 (2011) Article DOI: 10.1021/ml100304b BindingDB Entry DOI: 10.7270/Q2222VSB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 7 (Homo sapiens (Human)) | BDBM50337145 (9-chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.14E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysis | ACS Med Chem Lett 2: 195-200 (2011) Article DOI: 10.1021/ml100304b BindingDB Entry DOI: 10.7270/Q2222VSB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase DCLK1 (Homo sapiens (Human)) | BDBM50337127 (2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity to DCAMKL1 by immobilized ligand displacement assay | ACS Med Chem Lett 2: 195-200 (2011) Article DOI: 10.1021/ml100304b BindingDB Entry DOI: 10.7270/Q2222VSB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Activated CDC42 kinase 1 (Homo sapiens (Human)) | BDBM50337127 (2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity to TNK2 by immobilized ligand displacement assay | ACS Med Chem Lett 2: 195-200 (2011) Article DOI: 10.1021/ml100304b BindingDB Entry DOI: 10.7270/Q2222VSB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase DCLK2 (Homo sapiens (Human)) | BDBM50337127 (2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity to DCAMKL2 by immobilized ligand displacement assay | ACS Med Chem Lett 2: 195-200 (2011) Article DOI: 10.1021/ml100304b BindingDB Entry DOI: 10.7270/Q2222VSB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-G-associated kinase (Homo sapiens (Human)) | BDBM50337127 (2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity to GAK by immobilized ligand displacement assay | ACS Med Chem Lett 2: 195-200 (2011) Article DOI: 10.1021/ml100304b BindingDB Entry DOI: 10.7270/Q2222VSB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Non-receptor tyrosine-protein kinase TNK1 (Homo sapiens (Human)) | BDBM50337127 (2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity to TNK1 by immobilized ligand displacement assay | ACS Med Chem Lett 2: 195-200 (2011) Article DOI: 10.1021/ml100304b BindingDB Entry DOI: 10.7270/Q2222VSB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 7 (Homo sapiens (Human)) | BDBM50337126 (2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | >670 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity to ERK5 by immobilized ligand displacement assay | ACS Med Chem Lett 2: 195-200 (2011) Article DOI: 10.1021/ml100304b BindingDB Entry DOI: 10.7270/Q2222VSB | |||||||||||
More data for this Ligand-Target Pair |