Found 122 hits with Last Name = 'sheets' and Initial = 'kr' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039087
(3-(3-Fluoro-4-methoxy-phenyl)-6,7-dimethoxy-quinol...)Show InChI InChI=1S/C18H16FNO3/c1-21-16-5-4-11(7-14(16)19)13-6-12-8-17(22-2)18(23-3)9-15(12)20-10-13/h4-10H,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.003-0.005 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039073
(5,7-Dimethyl-3-thiophen-3-yl-quinoline | CHEMBL304...)Show InChI InChI=1S/C15H13NS/c1-10-5-11(2)14-7-13(8-16-15(14)6-10)12-3-4-17-9-12/h3-9H,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.001-0.005 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039041
(6,7-Dimethoxy-3-((E)-styryl)-quinoline | CHEMBL701...)Show InChI InChI=1S/C19H17NO2/c1-21-18-11-16-10-15(9-8-14-6-4-3-5-7-14)13-20-17(16)12-19(18)22-2/h3-13H,1-2H3/b9-8+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.001-0.005 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039071
(6,7-Dimethoxy-3-(4-methoxy-phenyl)-quinoline | CHE...)Show InChI InChI=1S/C18H17NO3/c1-20-15-6-4-12(5-7-15)14-8-13-9-17(21-2)18(22-3)10-16(13)19-11-14/h4-11H,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.001-0.015 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039082
(6,7-Dimethoxy-3-thiophen-3-yl-quinoline | CHEMBL66...)Show InChI InChI=1S/C15H13NO2S/c1-17-14-6-11-5-12(10-3-4-19-9-10)8-16-13(11)7-15(14)18-2/h3-9H,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.01-0.02 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039047
(5-Fluoro-3-thiophen-3-yl-quinoline | CHEMBL305056)Show InChI InChI=1S/C13H8FNS/c14-12-2-1-3-13-11(12)6-10(7-15-13)9-4-5-16-8-9/h1-8H | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of isolated human PDGF receptor phosphorylation |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039084
(3-(3-Fluoro-phenyl)-6,7-dimethoxy-quinoline | CHEM...)Show InChI InChI=1S/C17H14FNO2/c1-20-16-8-12-6-13(11-4-3-5-14(18)7-11)10-19-15(12)9-17(16)21-2/h3-10H,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.015-0.025 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039069
(7-Fluoro-3-thiophen-3-yl-quinoline | CHEMBL307093)Show InChI InChI=1S/C13H8FNS/c14-12-2-1-9-5-11(7-15-13(9)6-12)10-3-4-16-8-10/h1-8H | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.004-0.025 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039037
(4-(6,7-Dimethoxy-quinolin-3-yl)-phenol | CHEMBL303...)Show InChI InChI=1S/C17H15NO3/c1-20-16-8-12-7-13(11-3-5-14(19)6-4-11)10-18-15(12)9-17(16)21-2/h3-10,19H,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.02-0.03 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039067
(5-(6,7-Dimethoxy-quinolin-3-yl)-1H-pyridin-2-one |...)Show InChI InChI=1S/C16H14N2O3/c1-20-14-6-11-5-12(10-3-4-16(19)18-8-10)9-17-13(11)7-15(14)21-2/h3-9H,1-2H3,(H,18,19) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.015-0.03 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039072
(3-(5-Chloro-thiophen-2-yl)-6,7-dimethoxy-quinoline...)Show InChI InChI=1S/C15H12ClNO2S/c1-18-12-6-9-5-10(14-3-4-15(16)20-14)8-17-11(9)7-13(12)19-2/h3-8H,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.007-0.03 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039042
(5,7-Dimethoxy-3-thiophen-3-yl-quinoline | CHEMBL66...)Show InChI InChI=1S/C15H13NO2S/c1-17-12-6-14-13(15(7-12)18-2)5-11(8-16-14)10-3-4-19-9-10/h3-9H,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.025-0.03 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039090
(3-Cyclopent-1-enyl-6,7-dimethoxy-quinoline | CHEMB...)Show InChI InChI=1S/C16H17NO2/c1-18-15-8-12-7-13(11-5-3-4-6-11)10-17-14(12)9-16(15)19-2/h5,7-10H,3-4,6H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.02-0.04 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039094
(6,7-Dimethoxy-3-phenylethynyl-quinoline | CHEMBL67...)Show InChI InChI=1S/C19H15NO2/c1-21-18-11-16-10-15(9-8-14-6-4-3-5-7-14)13-20-17(16)12-19(18)22-2/h3-7,10-13H,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.02-0.05 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039044
(3-(4-Fluoro-phenyl)-6,7-dimethoxy-quinoline | CHEM...)Show InChI InChI=1S/C17H14FNO2/c1-20-16-8-12-7-13(11-3-5-14(18)6-4-11)10-19-15(12)9-17(16)21-2/h3-10H,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.035-0.06 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039057
(7-Methoxy-3-thiophen-3-yl-quinoline | CHEMBL68185)Show InChI InChI=1S/C14H11NOS/c1-16-13-3-2-10-6-12(8-15-14(10)7-13)11-4-5-17-9-11/h2-9H,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.002-0.06 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039065
(3-Benzyloxy-6,7-dimethoxy-quinoline | CHEMBL66932)Show InChI InChI=1S/C18H17NO3/c1-20-17-9-14-8-15(11-19-16(14)10-18(17)21-2)22-12-13-6-4-3-5-7-13/h3-11H,12H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.04-0.07 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039075
(6-Methoxy-3-thiophen-3-yl-quinoline | CHEMBL303184)Show InChI InChI=1S/C14H11NOS/c1-16-13-2-3-14-11(7-13)6-12(8-15-14)10-4-5-17-9-10/h2-9H,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.05-0.07 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039062
(6,7-Dimethoxy-3-(6-methoxy-pyridin-3-yl)-quinoline...)Show InChI InChI=1S/C17H16N2O3/c1-20-15-7-12-6-13(10-18-14(12)8-16(15)21-2)11-4-5-17(22-3)19-9-11/h4-10H,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.008-0.07 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039056
(Benzyl-(6,7-dimethoxy-quinolin-3-yl)-amine | CHEMB...)Show InChI InChI=1S/C18H18N2O2/c1-21-17-9-14-8-15(12-20-16(14)10-18(17)22-2)19-11-13-6-4-3-5-7-13/h3-10,12,19H,11H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.02-0.08 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039079
(6,7-Dimethoxy-3-thiophen-2-yl-quinoline | CHEMBL30...)Show InChI InChI=1S/C15H13NO2S/c1-17-13-7-10-6-11(15-4-3-5-19-15)9-16-12(10)8-14(13)18-2/h3-9H,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.04-0.08 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039052
(6,7-Dimethoxy-3-[(E)-2-(4-methoxy-phenyl)-vinyl]-q...)Show InChI InChI=1S/C20H19NO3/c1-22-17-8-6-14(7-9-17)4-5-15-10-16-11-19(23-2)20(24-3)12-18(16)21-13-15/h4-13H,1-3H3/b5-4+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.03-0.1 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039058
(6,7-Dimethoxy-3-(4-nitro-phenyl)-quinoline | CHEMB...)Show SMILES COc1cc2cc(cnc2cc1OC)-c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C17H14N2O4/c1-22-16-8-12-7-13(10-18-15(12)9-17(16)23-2)11-3-5-14(6-4-11)19(20)21/h3-10H,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.07-0.15 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039054
(6,7-Dimethoxy-3-phenyl-quinoline | CHEMBL66063)Show InChI InChI=1S/C17H15NO2/c1-19-16-9-13-8-14(12-6-4-3-5-7-12)11-18-15(13)10-17(16)20-2/h3-11H,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.07-0.15 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039053
(3-((E)-Styryl)-quinoline | CHEMBL65858)Show InChI InChI=1S/C17H13N/c1-2-6-14(7-3-1)10-11-15-12-16-8-4-5-9-17(16)18-13-15/h1-13H/b11-10+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.1-0.2 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039086
(3-(3,4-Difluoro-phenyl)-6,7-dimethoxy-quinoline | ...)Show InChI InChI=1S/C17H13F2NO2/c1-21-16-7-11-5-12(9-20-15(11)8-17(16)22-2)10-3-4-13(18)14(19)6-10/h3-9H,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.09-0.2 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039055
(4-(6,7-Dimethoxy-quinolin-3-yl)-benzoic acid ethyl...)Show InChI InChI=1S/C20H19NO4/c1-4-25-20(22)14-7-5-13(6-8-14)16-9-15-10-18(23-2)19(24-3)11-17(15)21-12-16/h5-12H,4H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.1-0.2 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039081
(3-Thiophen-3-yl-quinoline | CHEMBL304310)Show InChI InChI=1S/C13H9NS/c1-2-4-13-10(3-1)7-12(8-14-13)11-5-6-15-9-11/h1-9H | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.2-0.25 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039061
(6,7-Dimethoxy-3-(5-methoxy-thiophen-2-yl)-quinolin...)Show InChI InChI=1S/C16H15NO3S/c1-18-13-7-10-6-11(15-4-5-16(20-3)21-15)9-17-12(10)8-14(13)19-2/h4-9H,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.1-0.25 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039043
(3-(3,5-Difluoro-4-methoxy-phenyl)-6,7-dimethoxy-qu...)Show InChI InChI=1S/C18H15F2NO3/c1-22-16-7-11-4-12(9-21-15(11)8-17(16)23-2)10-5-13(19)18(24-3)14(20)6-10/h4-9H,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.2-0.4 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039093
(6,7-Dimethoxy-3-(4-methoxy-3-methyl-phenyl)-quinol...)Show InChI InChI=1S/C19H19NO3/c1-12-7-13(5-6-17(12)21-2)15-8-14-9-18(22-3)19(23-4)10-16(14)20-11-15/h5-11H,1-4H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.1-0.4 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039070
(6,7-Dimethoxy-3-(4-methoxy-3-nitro-phenyl)-quinoli...)Show SMILES COc1ccc(cc1[N+]([O-])=O)-c1cnc2cc(OC)c(OC)cc2c1 Show InChI InChI=1S/C18H16N2O5/c1-23-16-5-4-11(7-15(16)20(21)22)13-6-12-8-17(24-2)18(25-3)9-14(12)19-10-13/h4-10H,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.15-0.5 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039076
(3-Cyclopentyl-6,7-dimethoxy-quinoline | CHEMBL6678...)Show InChI InChI=1S/C16H19NO2/c1-18-15-8-12-7-13(11-5-3-4-6-11)10-17-14(12)9-16(15)19-2/h7-11H,3-6H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.1-0.5 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50039033
(3-Pyridin-3-yl-quinoline-6,7-diol | CHEMBL63356)Show InChI InChI=1S/C14H10N2O2/c17-13-5-10-4-11(9-2-1-3-15-7-9)8-16-12(10)6-14(13)18/h1-8,17-18H | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Concentration required to inhibit phosphorylation of isolated human epidermal growth factor tyrosine kinase receptor by 50% |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039049
(3-(2-Cyclohexyl-ethyl)-6,7-dimethoxy-quinoline | C...)Show InChI InChI=1S/C19H25NO2/c1-21-18-11-16-10-15(9-8-14-6-4-3-5-7-14)13-20-17(16)12-19(18)22-2/h10-14H,3-9H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.3-0.5 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039066
(7-Thiophen-3-yl-[1,3]dioxolo[4,5-g]quinoline | CHE...)Show InChI InChI=1S/C14H9NO2S/c1-2-18-7-9(1)11-3-10-4-13-14(17-8-16-13)5-12(10)15-6-11/h1-7H,8H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.2-0.6 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039038
(3-(1H-Indol-3-yl)-6,7-dimethoxy-quinoline | CHEMBL...)Show InChI InChI=1S/C19H16N2O2/c1-22-18-8-12-7-13(10-20-17(12)9-19(18)23-2)15-11-21-16-6-4-3-5-14(15)16/h3-11,21H,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.1-0.6 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50039091
((Z)-3-(3,4-Dimethoxy-phenyl)-2-pyridin-3-yl-acrylo...)Show InChI InChI=1S/C16H14N2O2/c1-19-15-6-5-12(9-16(15)20-2)8-14(10-17)13-4-3-7-18-11-13/h3-9,11H,1-2H3/b14-8+ | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Concentration required to inhibit phosphorylation of isolated human epidermal growth factor tyrosine kinase receptor by 50% |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039050
(6,7-Dimethoxy-3-pyridin-3-yl-quinoline | CHEMBL304...)Show InChI InChI=1S/C16H14N2O2/c1-19-15-7-12-6-13(11-4-3-5-17-9-11)10-18-14(12)8-16(15)20-2/h3-10H,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.1-0.8 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039051
(6,7-Dimethoxy-3-[2-(4-methoxy-phenyl)-ethyl]-quino...)Show InChI InChI=1S/C20H21NO3/c1-22-17-8-6-14(7-9-17)4-5-15-10-16-11-19(23-2)20(24-3)12-18(16)21-13-15/h6-13H,4-5H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.2-0.8 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039078
(3-(3-Chloro-thiophen-2-yl)-6,7-dimethoxy-quinoline...)Show InChI InChI=1S/C15H12ClNO2S/c1-18-13-6-9-5-10(15-11(16)3-4-20-15)8-17-12(9)7-14(13)19-2/h3-8H,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of isolated human PDGF receptor phosphorylation |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039040
(3-Cyclohexylethynyl-6,7-dimethoxy-quinoline | CHEM...)Show InChI InChI=1S/C19H21NO2/c1-21-18-11-16-10-15(9-8-14-6-4-3-5-7-14)13-20-17(16)12-19(18)22-2/h10-14H,3-7H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Concentration required to inhibit phosphorylation of isolated human PDGF receptor by 50%; 0.3-1 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039080
(6,7-Dimethoxy-3-p-tolyl-quinoline | CHEMBL67219)Show InChI InChI=1S/C18H17NO2/c1-12-4-6-13(7-5-12)15-8-14-9-17(20-2)18(21-3)10-16(14)19-11-15/h4-11H,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.5-2 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039095
(6,7-Dimethoxy-3-(2-methoxy-phenyl)-quinoline | CHE...)Show InChI InChI=1S/C18H17NO3/c1-20-16-7-5-4-6-14(16)13-8-12-9-17(21-2)18(22-3)10-15(12)19-11-13/h4-11H,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of isolated human PDGF receptor phosphorylation |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039039
(6,7-Dichloro-3-thiophen-3-yl-quinoline | CHEMBL667...)Show InChI InChI=1S/C13H7Cl2NS/c14-11-4-9-3-10(8-1-2-17-7-8)6-16-13(9)5-12(11)15/h1-7H | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 1-2 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039088
(6,7-Dimethoxy-3-(3-methoxy-phenyl)-quinoline | CHE...)Show InChI InChI=1S/C18H17NO3/c1-20-15-6-4-5-12(8-15)14-7-13-9-17(21-2)18(22-3)10-16(13)19-11-14/h4-11H,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 1-2 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039091
((Z)-3-(3,4-Dimethoxy-phenyl)-2-pyridin-3-yl-acrylo...)Show InChI InChI=1S/C16H14N2O2/c1-19-15-6-5-12(9-16(15)20-2)8-14(10-17)13-4-3-7-18-11-13/h3-9,11H,1-2H3/b14-8+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.5-3 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039085
(6,7-Difluoro-3-thiophen-3-yl-quinoline | CHEMBL681...)Show InChI InChI=1S/C13H7F2NS/c14-11-4-9-3-10(8-1-2-17-7-8)6-16-13(9)5-12(11)15/h1-7H | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 2-4 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039077
(4-(6,7-Dimethoxy-quinolin-3-yl)-benzoic acid | CHE...)Show InChI InChI=1S/C18H15NO4/c1-22-16-8-13-7-14(10-19-15(13)9-17(16)23-2)11-3-5-12(6-4-11)18(20)21/h3-10H,1-2H3,(H,20,21) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 0.7-5 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50039074
(3-(3,4-Dichloro-phenyl)-6,7-dimethoxy-quinoline | ...)Show InChI InChI=1S/C17H13Cl2NO2/c1-21-16-7-11-5-12(9-20-15(11)8-17(16)22-2)10-3-4-13(18)14(19)6-10/h3-9H,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of human PDGF receptor phosphorylation; 1-7 |
J Med Chem 37: 2129-37 (1994)
BindingDB Entry DOI: 10.7270/Q29Z93Z8 |
More data for this Ligand-Target Pair | |