Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA polymerase kappa (Homo sapiens (Human)) | BDBM50379292 (CHEMBL2011646) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 9.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo Curated by ChEMBL | Assay Description Competitive inhibition of human C-terminal-His6-tagged DNA polymerase kappa expressed in Escherichia coli using dTTP as substrate by Dixon plot analy... | J Nat Prod 75: 135-41 (2012) Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase kappa (Homo sapiens (Human)) | BDBM50379292 (CHEMBL2011646) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.81E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo Curated by ChEMBL | Assay Description Non-competitive inhibition of human C-terminal-His6-tagged DNA polymerase kappa expressed in Escherichia coli using ploy(dA)/oligo(dT)18 as substrate... | J Nat Prod 75: 135-41 (2012) Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase subunit gamma-1 (Homo sapiens (Human)) | BDBM21688 (1-cyclopropyl-7-[4-(4-{4-[(3-ethyl-4-methylphenyl)...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 6.84E+5 | -18.8 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
Microbiotix | Assay Description Reaction velocities were determined at each dGTP concentration and used to create double reciprocal plots of velocity versus dGTP concentration. The ... | Antimicrob Agents Chemother 51: 119-27 (2007) Article DOI: 10.1128/AAC.01311-05 BindingDB Entry DOI: 10.7270/Q2988599 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase subunit gamma-1 (Homo sapiens (Human)) | BDBM21686 (3-(4-hydroxybutyl)-6-(3-ethyl-4-methylanilino)urac...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.01E+6 | >-17.8 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
Microbiotix | Assay Description Reaction velocities were determined at each dGTP concentration and used to create double reciprocal plots of velocity versus dGTP concentration. The ... | Antimicrob Agents Chemother 51: 119-27 (2007) Article DOI: 10.1128/AAC.01311-05 BindingDB Entry DOI: 10.7270/Q2988599 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase subunit gamma-1 (Homo sapiens (Human)) | BDBM50408427 (CHEMBL483492) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Max-Delbr�ck-Centrum f�r Molekulare Medizin Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of cellular DNA polymerase (gamma) | J Med Chem 41: 2040-6 (1998) Article DOI: 10.1021/jm9704210 BindingDB Entry DOI: 10.7270/Q2FT8MQT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase subunit gamma-1 (Homo sapiens (Human)) | BDBM50408426 (CHEMBL2092833) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Max-Delbr�ck-Centrum f�r Molekulare Medizin Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of cellular DNA polymerase (gamma) | J Med Chem 41: 2040-6 (1998) Article DOI: 10.1021/jm9704210 BindingDB Entry DOI: 10.7270/Q2FT8MQT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase subunit gamma-1 (Homo sapiens (Human)) | BDBM50408426 (CHEMBL2092833) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Max-Delbr�ck-Centrum f�r Molekulare Medizin Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of cellular DNA polymerase (gamma) | J Med Chem 41: 2040-6 (1998) Article DOI: 10.1021/jm9704210 BindingDB Entry DOI: 10.7270/Q2FT8MQT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase subunit gamma-1 (Homo sapiens (Human)) | BDBM50408425 (CHEMBL2092835) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Max-Delbr�ck-Centrum f�r Molekulare Medizin Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of cellular DNA polymerase (gamma) | J Med Chem 41: 2040-6 (1998) Article DOI: 10.1021/jm9704210 BindingDB Entry DOI: 10.7270/Q2FT8MQT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase subunit gamma-1 (Homo sapiens (Human)) | BDBM50448482 (CHEMBL3126408) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
St. John's University Curated by ChEMBL | Assay Description Inhibition of DNA polymerase-gamma (unknown origin) assessed as incorporation of Br(d)UTP by colorimetric analysis | Bioorg Med Chem 22: 116-25 (2013) Article DOI: 10.1016/j.bmc.2013.11.046 BindingDB Entry DOI: 10.7270/Q23T9JQ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase kappa (Homo sapiens (Human)) | BDBM50250399 (5-Hydroxy-4-{(R)-6-hydroxy-5-[(E)-4-methyl-6-(2,6,...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Connecticut Health Center Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase kappa (19 to 526 residues) preincubated for 15 mins followed by replicating non-damaged DNA substrate addition mea... | J Med Chem 59: 9321-9336 (2016) BindingDB Entry DOI: 10.7270/Q2ZC84TJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase kappa (Homo sapiens (Human)) | BDBM50250399 (5-Hydroxy-4-{(R)-6-hydroxy-5-[(E)-4-methyl-6-(2,6,...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Connecticut Health Center Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase kappa (19 to 526 residues)-mediated TLS past acrolein derived ring-opened reduced form of gamma-HOPdG lesions prei... | J Med Chem 59: 9321-9336 (2016) BindingDB Entry DOI: 10.7270/Q2ZC84TJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase kappa (Homo sapiens (Human)) | BDBM50318907 (2-Ethoxy-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmet...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Connecticut Health Center Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase kappa (19 to 526 residues)-mediated TLS past acrolein derived ring-opened reduced form of gamma-HOPdG lesions prei... | J Med Chem 59: 9321-9336 (2016) BindingDB Entry DOI: 10.7270/Q2ZC84TJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase kappa (Homo sapiens (Human)) | BDBM50191327 (CHEMBL3960997) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Connecticut Health Center Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase kappa (19 to 526 residues)-mediated TLS past acrolein derived ring-opened reduced form of gamma-HOPdG lesions prei... | J Med Chem 59: 9321-9336 (2016) BindingDB Entry DOI: 10.7270/Q2ZC84TJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase kappa (Homo sapiens (Human)) | BDBM50356642 (CHEMBL1917196) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Prefectural University Curated by ChEMBL | Assay Description Inhibition of C-terminal His6-tagged human DNA polymerase kappa (amino acids 1 to 560) using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA tem... | Bioorg Med Chem 19: 5803-12 (2011) Article DOI: 10.1016/j.bmc.2011.08.023 BindingDB Entry DOI: 10.7270/Q2DZ0989 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase kappa (Homo sapiens (Human)) | BDBM50356643 (CHEMBL1917198) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Prefectural University Curated by ChEMBL | Assay Description Inhibition of C-terminal His6-tagged human DNA polymerase kappa (amino acids 1 to 560) using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA tem... | Bioorg Med Chem 19: 5803-12 (2011) Article DOI: 10.1016/j.bmc.2011.08.023 BindingDB Entry DOI: 10.7270/Q2DZ0989 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase kappa (Homo sapiens (Human)) | BDBM50318907 (2-Ethoxy-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmet...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 9.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Connecticut Health Center Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase kappa (19 to 526 residues) preincubated for 15 mins followed by replicating non-damaged DNA substrate addition mea... | J Med Chem 59: 9321-9336 (2016) BindingDB Entry DOI: 10.7270/Q2ZC84TJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase subunit gamma-1 (Homo sapiens (Human)) | BDBM50191511 (2-{4-[4'-chloro-4-(2-oxo-pyrrolidin-1-yl)-biphenyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Central Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of DNA polymerase gamma | J Med Chem 49: 4721-36 (2006) Article DOI: 10.1021/jm060269e BindingDB Entry DOI: 10.7270/Q2FN15TD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase subunit gamma-1 (Homo sapiens (Human)) | BDBM50428818 (CHEMBL3142662) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.15E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University Curated by ChEMBL | Assay Description Inhibition of rat DNA polymerase beta using poly(dA)/oligo(dT)18 (A/T, 2/1)/dTTP DNA template-primer substrate measured at 37 degC for 60 mins | Bioorg Med Chem 21: 403-11 (2012) Article DOI: 10.1016/j.bmc.2012.11.024 BindingDB Entry DOI: 10.7270/Q2833TC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase kappa (Homo sapiens (Human)) | BDBM50104668 (CHEMBL3593571) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Connecticut Health Center Curated by ChEMBL | Assay Description Inhibition of C-terminal His6-tagged human DNA polymerase kappa (1 to 560 residues) expressed in Escherichia coli using poly(dA)/oligo(dT)18 and [3H]... | J Med Chem 59: 9321-9336 (2016) BindingDB Entry DOI: 10.7270/Q2ZC84TJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase kappa (Homo sapiens (Human)) | BDBM50191327 (CHEMBL3960997) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Connecticut Health Center Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase kappa (19 to 526 residues) preincubated for 15 mins followed by replicating non-damaged DNA substrate addition mea... | J Med Chem 59: 9321-9336 (2016) BindingDB Entry DOI: 10.7270/Q2ZC84TJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase subunit gamma-1 (Homo sapiens (Human)) | BDBM50251277 (CHEMBL458178 | Kasanosin A) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Science Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase gamma | Bioorg Med Chem 16: 4594-9 (2008) Article DOI: 10.1016/j.bmc.2008.02.037 BindingDB Entry DOI: 10.7270/Q2X066TH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase kappa (Homo sapiens (Human)) | BDBM50379292 (CHEMBL2011646) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.86E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human C-terminal-His6-tagged DNA polymerase kappa expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into po... | J Nat Prod 75: 135-41 (2012) Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase subunit gamma-1 (Homo sapiens (Human)) | BDBM50408427 (CHEMBL483492) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Max-Delbr�ck-Centrum f�r Molekulare Medizin Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of cellular DNA polymerase (gamma) | J Med Chem 41: 2040-6 (1998) Article DOI: 10.1021/jm9704210 BindingDB Entry DOI: 10.7270/Q2FT8MQT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase subunit gamma-1 (Homo sapiens (Human)) | BDBM50408425 (CHEMBL2092835) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Max-Delbr�ck-Centrum f�r Molekulare Medizin Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of cellular DNA polymerase (gamma) | J Med Chem 41: 2040-6 (1998) Article DOI: 10.1021/jm9704210 BindingDB Entry DOI: 10.7270/Q2FT8MQT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase subunit gamma-1 (Homo sapiens (Human)) | BDBM50335554 (({[({[2-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)e...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.94E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
USA. Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase gamma by microplate reader analysis | Antimicrob Agents Chemother 53: 2777-84 (2009) Article DOI: 10.1128/AAC.00103-09 BindingDB Entry DOI: 10.7270/Q2M32W2N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase kappa (Homo sapiens (Human)) | BDBM50379293 (CHEMBL2011648) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.98E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human C-terminal-His6-tagged DNA polymerase kappa expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into po... | J Nat Prod 75: 135-41 (2012) Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase kappa (Homo sapiens (Human)) | BDBM50375301 (CHEMBL260980) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.98E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Science Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase kappa | Bioorg Med Chem 16: 2939-44 (2008) Article DOI: 10.1016/j.bmc.2007.12.044 BindingDB Entry DOI: 10.7270/Q2J67HST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase subunit gamma-1 (Homo sapiens (Human)) | BDBM50251278 (CHEMBL457091 | Kasanosin B) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Science Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase gamma | Bioorg Med Chem 16: 4594-9 (2008) Article DOI: 10.1016/j.bmc.2008.02.037 BindingDB Entry DOI: 10.7270/Q2X066TH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase subunit gamma-1 (Homo sapiens (Human)) | BDBM50205415 (({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Max-Delbr�ck-Centrum f�r Molekulare Medizin Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of cellular DNA polymerase (gamma) | J Med Chem 41: 2040-6 (1998) Article DOI: 10.1021/jm9704210 BindingDB Entry DOI: 10.7270/Q2FT8MQT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase subunit gamma-1 (Homo sapiens (Human)) | BDBM50333127 ((beta-D-2',3'-dideoxy-5'-F-cytidine-5'-triphosphat...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
303A College Road East Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase gamma assessed as incorporation of [alpha-32P]dCTP up to 1mM preincubated for 30 mins by whatman DE81 paper bindin... | Antimicrob Agents Chemother 54: 3187-96 (2010) Article DOI: 10.1128/AAC.00399-10 BindingDB Entry DOI: 10.7270/Q2G1614S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase kappa (Homo sapiens (Human)) | BDBM50375300 (TALAROFLAVONE) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.65E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Science Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase kappa | Bioorg Med Chem 16: 2939-44 (2008) Article DOI: 10.1016/j.bmc.2007.12.044 BindingDB Entry DOI: 10.7270/Q2J67HST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase kappa (Homo sapiens (Human)) | BDBM50379294 (CHEMBL2011647) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.89E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human C-terminal-His6-tagged DNA polymerase kappa expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into po... | J Nat Prod 75: 135-41 (2012) Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase subunit gamma-1 (Homo sapiens (Human)) | BDBM50408428 (CHEMBL2092834) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Max-Delbr�ck-Centrum f�r Molekulare Medizin Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of cellular DNA polymerase (gamma) | J Med Chem 41: 2040-6 (1998) Article DOI: 10.1021/jm9704210 BindingDB Entry DOI: 10.7270/Q2FT8MQT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase subunit gamma-1 (Homo sapiens (Human)) | BDBM50021053 (CHEMBL3287609) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Biota Scientific Management Pty. Ltd. Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase gamma | ACS Med Chem Lett 5: 679-84 (2014) Article DOI: 10.1021/ml500077j BindingDB Entry DOI: 10.7270/Q2B56MBN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase subunit gamma-1 (Homo sapiens (Human)) | BDBM50408428 (CHEMBL2092834) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Max-Delbr�ck-Centrum f�r Molekulare Medizin Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of cellular DNA polymerase (gamma) | J Med Chem 41: 2040-6 (1998) Article DOI: 10.1021/jm9704210 BindingDB Entry DOI: 10.7270/Q2FT8MQT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase subunit gamma-1 (Homo sapiens (Human)) | BDBM50591035 (CHEMBL5187422) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00998 BindingDB Entry DOI: 10.7270/Q2C53QVS | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase subunit gamma-1 (Homo sapiens (Human)) | BDBM50336502 (10-acetyl-11-(2,4-dichlorophenyl)-3,3-dimethyl-2,3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Tibotec BVBA Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase gamma | Antimicrob Agents Chemother 52: 4420-31 (2008) Article DOI: 10.1128/AAC.00669-08 BindingDB Entry DOI: 10.7270/Q26M3732 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase subunit gamma-1 (Homo sapiens (Human)) | BDBM50090910 (3alpha,16,17,18-tetrahydroxyaphidicolone | 6,13-di...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
303A College Road East Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase gamma assessed as incorporation of [alpha-32P]dCTP up to 1mM preincubated for 30 mins by whatman DE81 paper bindin... | Antimicrob Agents Chemother 54: 3187-96 (2010) Article DOI: 10.1128/AAC.00399-10 BindingDB Entry DOI: 10.7270/Q2G1614S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase subunit gamma-1 (Homo sapiens (Human)) | BDBM50336503 (10-acetyl-11-(3-(benzyloxy)-4-methoxyphenyl)-3,3-d...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Tibotec BVBA Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase gamma | Antimicrob Agents Chemother 52: 4420-31 (2008) Article DOI: 10.1128/AAC.00669-08 BindingDB Entry DOI: 10.7270/Q26M3732 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase subunit gamma-1 (Homo sapiens (Human)) | BDBM50335556 (CHEMBL1652469 | [({[({2-[2-amino-6-(cyclopropylami...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
USA. Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase gamma by microplate reader analysis | Antimicrob Agents Chemother 53: 2777-84 (2009) Article DOI: 10.1128/AAC.00103-09 BindingDB Entry DOI: 10.7270/Q2M32W2N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase subunit gamma-1 (Homo sapiens (Human)) | BDBM50428818 (CHEMBL3142662) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase gamma using poly(dA)/oligo(dT)18 (A/T, 2/1)/dTTP DNA template-primer substrate measured at 37 degC for 60 mins | Bioorg Med Chem 21: 403-11 (2012) Article DOI: 10.1016/j.bmc.2012.11.024 BindingDB Entry DOI: 10.7270/Q2833TC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase subunit gamma-1 (Homo sapiens (Human)) | BDBM50428818 (CHEMBL3142662) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase kappa using poly(dA)/oligo(dT)18 (A/T, 2/1)/dTTP DNA template-primer substrate measured at 37 degC for 60 mins | Bioorg Med Chem 21: 403-11 (2012) Article DOI: 10.1016/j.bmc.2012.11.024 BindingDB Entry DOI: 10.7270/Q2833TC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase subunit gamma-1 (Homo sapiens (Human)) | BDBM50428818 (CHEMBL3142662) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase eta using poly(dA)/oligo(dT)18 (A/T, 2/1)/dTTP DNA template-primer substrate measured at 37 degC for 60 mins | Bioorg Med Chem 21: 403-11 (2012) Article DOI: 10.1016/j.bmc.2012.11.024 BindingDB Entry DOI: 10.7270/Q2833TC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase subunit gamma-1 (Homo sapiens (Human)) | BDBM50428818 (CHEMBL3142662) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase mu using poly(dA)/oligo(dT)18 (A/T, 2/1)/dTTP DNA template-primer substrate measured at 37 degC for 60 mins | Bioorg Med Chem 21: 403-11 (2012) Article DOI: 10.1016/j.bmc.2012.11.024 BindingDB Entry DOI: 10.7270/Q2833TC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase subunit gamma-1 (Homo sapiens (Human)) | BDBM50428818 (CHEMBL3142662) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University Curated by ChEMBL | Assay Description Inhibition of calf TdT polymerase measured at 37 degC for 60 mins | Bioorg Med Chem 21: 403-11 (2012) Article DOI: 10.1016/j.bmc.2012.11.024 BindingDB Entry DOI: 10.7270/Q2833TC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase kappa (Homo sapiens (Human)) | BDBM50448688 (Pecilocin | Variotin) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University Curated by ChEMBL | Assay Description Inhibition of C-terminal His-6-tagged human DNA polymerase kappa expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into p... | Bioorg Med Chem 22: 1070-6 (2014) Article DOI: 10.1016/j.bmc.2013.12.038 BindingDB Entry DOI: 10.7270/Q22V2HMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase subunit gamma-1 (Homo sapiens (Human)) | BDBM50428818 (CHEMBL3142662) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase lambda using poly(dA)/oligo(dT)18 (A/T, 2/1)/dTTP DNA template-primer substrate measured at 37 degC for 60 mins | Bioorg Med Chem 21: 403-11 (2012) Article DOI: 10.1016/j.bmc.2012.11.024 BindingDB Entry DOI: 10.7270/Q2833TC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase kappa (Homo sapiens (Human)) | BDBM50448690 (CHEMBL3127728) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University Curated by ChEMBL | Assay Description Inhibition of C-terminal His-6-tagged human DNA polymerase kappa expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into p... | Bioorg Med Chem 22: 1070-6 (2014) Article DOI: 10.1016/j.bmc.2013.12.038 BindingDB Entry DOI: 10.7270/Q22V2HMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase kappa (Homo sapiens (Human)) | BDBM50448691 (CHEMBL3127729) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University Curated by ChEMBL | Assay Description Inhibition of C-terminal His-6-tagged human DNA polymerase kappa expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into p... | Bioorg Med Chem 22: 1070-6 (2014) Article DOI: 10.1016/j.bmc.2013.12.038 BindingDB Entry DOI: 10.7270/Q22V2HMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase kappa (Homo sapiens (Human)) | BDBM50448689 (CHEMBL3127730) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University Curated by ChEMBL | Assay Description Inhibition of C-terminal His-6-tagged human DNA polymerase kappa expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into p... | Bioorg Med Chem 22: 1070-6 (2014) Article DOI: 10.1016/j.bmc.2013.12.038 BindingDB Entry DOI: 10.7270/Q22V2HMW | |||||||||||
More data for this Ligand-Target Pair |
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