Compile Data Set for Download or QSAR

Found 67 hits Enz. Inhib. hit(s) with Target = 'Carnitine O-palmitoyltransferase 1, muscle isoform'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50046145 (2-[6-hydroxy-4,4-dimethyl-6-pentadecyl-(2R,6S)-1,4...) Show SMILES CCCCCCCCCCCCCCC[C@@]1(O)C[N+](C)(C)C[C@@H](CC([O-])=O)O1 Show InChI InChI=1S/C23H45NO4/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-23(27)20-24(2,3)19-21(28-23)18-22(25)26/h21,27H,4-20H2,1-3H3/t21-,23+/m1/s1	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Louisiana State University Curated by ChEMBL					Assay Description Compound was evaluated for its ability to inhibit carnitine palmitoyltransferase I activity in intact mitochondria from rat heart				J Med Chem 36: 237-42 (1993) BindingDB Entry DOI: 10.7270/Q2P849ZC
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50037268 ((-)-Carnitine | (-)-L-Carnitine | (3R)-3-hydroxy-4...) Show SMILES C[N+](C)(C)C[C@H](O)CC([O-])=O |r| Show InChI InChI=1S/C7H15NO3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3/t6-/m1/s1	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents	PubMed	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description Tested against neonatal rat cardiac myocyte carnitine palmitoyltransferase 1				J Med Chem 37: 3247-51 (1994) BindingDB Entry DOI: 10.7270/Q2VM4CXR
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50037262 ((R)-3-Hydroxy-5,5-dimethyl-hexanoic acid anion) Show SMILES CC(C)(C)C[C@@H](O)CC([O-])=O Show InChI InChI=1S/C8H16O3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3,(H,10,11)/p-1/t6-/m0/s1	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	PubMed	1.40E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description Tested against neonatal rat cardiac myocyte carnitine palmitoyltransferase 1				J Med Chem 37: 3247-51 (1994) BindingDB Entry DOI: 10.7270/Q2VM4CXR
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50037261 (3-Hydroxy-5,5-dimethyl-hexanoic acid anion) Show SMILES CC(C)(C)CC(O)CC([O-])=O Show InChI InChI=1S/C8H16O3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3,(H,10,11)/p-1	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	PubMed	3.60E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description Tested against neonatal rat cardiac myocyte carnitine palmitoyltransferase 1				J Med Chem 37: 3247-51 (1994) BindingDB Entry DOI: 10.7270/Q2VM4CXR
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50403039 (CHEMBL2216778) Show SMILES COc1ccc(Cl)cc1S(=O)(=O)N1CC(Oc2ccc(cc12)C(=O)Nc1cccc(F)c1)C(O)=O Show InChI InChI=1S/C23H18ClFN2O7S/c1-33-19-8-6-14(24)10-21(19)35(31,32)27-12-20(23(29)30)34-18-7-5-13(9-17(18)27)22(28)26-16-4-2-3-15(25)11-16/h2-11,20H,12H2,1H3,(H,26,28)(H,29,30)	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Maximal inhibition of rat CPT1A				J Med Chem 54: 3109-52 (2011) Article DOI: 10.1021/jm100809g BindingDB Entry DOI: 10.7270/Q29K4CDQ
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50403029 (CHEMBL2216792) Show SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)n1cnc2c(N)cnnc12)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)[C@@]1(CCCCCCOc2ccc(Cl)cc2)CO1 |r| Show InChI InChI=1S/C36H53ClN7O19P3S/c1-35(2,30(47)32(48)40-13-11-26(45)39-14-16-67-34(49)36(20-58-36)12-5-3-4-6-15-57-23-9-7-22(37)8-10-23)19-60-66(55,56)63-65(53,54)59-18-25-29(62-64(50,51)52)28(46)33(61-25)44-21-41-27-24(38)17-42-43-31(27)44/h7-10,17,21,25,28-30,33,46-47H,3-6,11-16,18-20H2,1-2H3,(H2,38,43)(H,39,45)(H,40,48)(H,53,54)(H,55,56)(H2,50,51,52)/t25-,28-,29-,30+,33-,36-/m1/s1	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition of rat CPT1B expressed in intact Saccharomyces cerevisiae using [methyl-3H]carnitine by radiometric assay				J Med Chem 54: 3109-52 (2011) Article DOI: 10.1021/jm100809g BindingDB Entry DOI: 10.7270/Q29K4CDQ
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50403040 (CHEMBL2216779) Show SMILES COc1ccc(Cl)cc1S(=O)(=O)N1CCc2ccc(cc12)C(=O)Nc1ccc(cc1)C(O)=O Show InChI InChI=1S/C23H19ClN2O6S/c1-32-20-9-6-17(24)13-21(20)33(30,31)26-11-10-14-2-3-16(12-19(14)26)22(27)25-18-7-4-15(5-8-18)23(28)29/h2-9,12-13H,10-11H2,1H3,(H,25,27)(H,28,29)	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Maximal inhibition of rat CPT1A				J Med Chem 54: 3109-52 (2011) Article DOI: 10.1021/jm100809g BindingDB Entry DOI: 10.7270/Q29K4CDQ
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50403037 (CHEMBL2216774) Show SMILES O=C(COc1ccccc1)N1CCCC[C@@H]1c1nc(cs1)-c1ccccn1 |r| Show InChI InChI=1S/C21H21N3O2S/c25-20(14-26-16-8-2-1-3-9-16)24-13-7-5-11-19(24)21-23-18(15-27-21)17-10-4-6-12-22-17/h1-4,6,8-10,12,15,19H,5,7,11,13-14H2/t19-/m1/s1	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Maximal inhibition of rat CPT1A				J Med Chem 54: 3109-52 (2011) Article DOI: 10.1021/jm100809g BindingDB Entry DOI: 10.7270/Q29K4CDQ
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50403041 (CHEMBL2216776) Show SMILES FC(F)(F)c1cccc(Cn2nc(C(=O)NCc3cccs3)c3ccccc23)c1 Show InChI InChI=1S/C21H16F3N3OS/c22-21(23,24)15-6-3-5-14(11-15)13-27-18-9-2-1-8-17(18)19(26-27)20(28)25-12-16-7-4-10-29-16/h1-11H,12-13H2,(H,25,28)	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Maximal inhibition of rat CPT1A				J Med Chem 54: 3109-52 (2011) Article DOI: 10.1021/jm100809g BindingDB Entry DOI: 10.7270/Q29K4CDQ
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Homo sapiens (Human))	BDBM50403031 (CHEMBL2216771) Show SMILES OC(=O)C(=O)c1ccc(OCCOc2ccc3ccccc3c2)s1 Show InChI InChI=1S/C18H14O5S/c19-17(18(20)21)15-7-8-16(24-15)23-10-9-22-14-6-5-12-3-1-2-4-13(12)11-14/h1-8,11H,9-10H2,(H,20,21)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition of human CPT1B				J Med Chem 54: 3109-52 (2011) Article DOI: 10.1021/jm100809g BindingDB Entry DOI: 10.7270/Q29K4CDQ
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50403038 (CHEMBL2216777) Show SMILES COc1ccc(C)cc1S(=O)(=O)N1CCCc2ccc(cc12)C(=O)Nc1ccc(CC(O)=O)cc1 Show InChI InChI=1S/C26H26N2O6S/c1-17-5-12-23(34-2)24(14-17)35(32,33)28-13-3-4-19-8-9-20(16-22(19)28)26(31)27-21-10-6-18(7-11-21)15-25(29)30/h5-12,14,16H,3-4,13,15H2,1-2H3,(H,27,31)(H,29,30)	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Maximal inhibition of rat CPT1A				J Med Chem 54: 3109-52 (2011) Article DOI: 10.1021/jm100809g BindingDB Entry DOI: 10.7270/Q29K4CDQ
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Homo sapiens (Human))	BDBM50403028 (CHEMBL2216769) Show SMILES CCCCCCCC[C@H]1OC(=O)C(CSCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2OP(O)(O)=O)n2cnc3c(N)cnnc23)[C@@H]1C(O)=O |r| Show InChI InChI=1S/C35H58N7O20P3S/c1-4-5-6-7-8-9-10-22-25(33(47)48)20(34(49)60-22)17-66-14-13-37-24(43)11-12-38-31(46)29(45)35(2,3)18-58-65(55,56)62-64(53,54)57-16-23-28(61-63(50,51)52)27(44)32(59-23)42-19-39-26-21(36)15-40-41-30(26)42/h15,19-20,22-23,25,27-29,32,44-45H,4-14,16-18H2,1-3H3,(H2,36,41)(H,37,43)(H,38,46)(H,47,48)(H,53,54)(H,55,56)(H2,50,51,52)/t20?,22-,23-,25+,27-,28-,29+,32-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition of CPT1B				J Med Chem 54: 3109-52 (2011) Article DOI: 10.1021/jm100809g BindingDB Entry DOI: 10.7270/Q29K4CDQ
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50260111 (CHEBI:15531 | MALONYL-COENZYME A) Show SMILES CC(C)(CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)n1cnc2c(N)ncnc12)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CC(O)=O |r| Show InChI InChI=1S/C24H38N7O19P3S/c1-24(2,19(37)22(38)27-4-3-13(32)26-5-6-54-15(35)7-14(33)34)9-47-53(44,45)50-52(42,43)46-8-12-18(49-51(39,40)41)17(36)23(48-12)31-11-30-16-20(25)28-10-29-21(16)31/h10-12,17-19,23,36-37H,3-9H2,1-2H3,(H,26,32)(H,27,38)(H,33,34)(H,42,43)(H,44,45)(H2,25,28,29)(H2,39,40,41)/t12-,17-,18-,19+,23-/m1/s1	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kosterlitz Centre for Therapeutics, University of Aberdeen , Foresterhill, Aberdeen, AB25 2ZD, U.K. Curated by ChEMBL					Assay Description Inhibition of rat heart mitochondrial CPT-1				J Med Chem 60: 2780-2789 (2017) Article DOI: 10.1021/acs.jmedchem.6b01592 BindingDB Entry DOI: 10.7270/Q20867SV
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM80613 (1-(2,3,4-Trimethoxy-benzyl)-piperazine | 1-(2,3,4-...) Show SMILES COc1ccc(CN2CCNCC2)c(OC)c1OC Show InChI InChI=1S/C14H22N2O3/c1-17-12-5-4-11(13(18-2)14(12)19-3)10-16-8-6-15-7-9-16/h4-5,15H,6-10H2,1-3H3	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition of CPT1A in rat myocardium				J Med Chem 54: 3109-52 (2011) Article DOI: 10.1021/jm100809g BindingDB Entry DOI: 10.7270/Q29K4CDQ
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50122839 (CHEMBL106227 | [3-Carboxy-2-(3-tetradecyl-ureido)-...) Show SMILES CCCCCCCCCCCCCCNC(=O)N[C@H](CC([O-])=O)C[N+](C)(C)C Show InChI InChI=1S/C22H45N3O3/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-23-22(28)24-20(18-21(26)27)19-25(2,3)4/h20H,5-19H2,1-4H3,(H2-,23,24,26,27,28)/t20-/m1/s1	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Maximal inhibition of rat CPT1A				J Med Chem 54: 3109-52 (2011) Article DOI: 10.1021/jm100809g BindingDB Entry DOI: 10.7270/Q29K4CDQ
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50101594 (CHEMBL80493 | [3-Carboxy-2-(decane-1-sulfonylamino...) Show SMILES CCCCCCCCCCS(=O)(=O)NC(CC([O-])=O)C[N+](C)(C)C Show InChI InChI=1S/C17H36N2O4S/c1-5-6-7-8-9-10-11-12-13-24(22,23)18-16(14-17(20)21)15-19(2,3)4/h16,18H,5-15H2,1-4H3	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sigma Tau Pharmaceutical Industries S.p.A. Curated by ChEMBL					Assay Description Inhibitory activity against rat heart mitochondrial carnitine palmitoyltransferase 1b using [14C]-palmitoyl-CoA as radioligand				J Med Chem 44: 2383-6 (2001) BindingDB Entry DOI: 10.7270/Q2930SG7
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50101604 (CHEMBL309568 | [3-Carboxy-2-(dodecane-1-sulfonylam...) Show SMILES CCCCCCCCCCCCS(=O)(=O)N[C@@H](CC([O-])=O)C[N+](C)(C)C Show InChI InChI=1S/C19H40N2O4S/c1-5-6-7-8-9-10-11-12-13-14-15-26(24,25)20-18(16-19(22)23)17-21(2,3)4/h18,20H,5-17H2,1-4H3/t18-/m0/s1	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sigma Tau Pharmaceutical Industries S.p.A. Curated by ChEMBL					Assay Description In vitro inhibition of [14C]-palmitoyl-CoA and carnitine binding to carnitine palmitoyltransferase I of rat heart mitochondria				J Med Chem 46: 303-9 (2003) Article DOI: 10.1021/jm020979u BindingDB Entry DOI: 10.7270/Q2N015WM
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50101598 (CHEMBL307495 | [3-Carboxy-2-(dodecane-1-sulfonylam...) Show SMILES CCCCCCCCCCCCS(=O)(=O)N[C@H](CC([O-])=O)C[N+](C)(C)C Show InChI InChI=1S/C19H40N2O4S/c1-5-6-7-8-9-10-11-12-13-14-15-26(24,25)20-18(16-19(22)23)17-21(2,3)4/h18,20H,5-17H2,1-4H3/t18-/m1/s1	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sigma Tau Pharmaceutical Industries S.p.A. Curated by ChEMBL					Assay Description Inhibitory activity against rat heart mitochondrial carnitine palmitoyltransferase 1b using [14C]-palmitoyl-CoA as radioligand				J Med Chem 44: 2383-6 (2001) BindingDB Entry DOI: 10.7270/Q2930SG7
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Homo sapiens (Human))	BDBM50403039 (CHEMBL2216778) Show SMILES COc1ccc(Cl)cc1S(=O)(=O)N1CC(Oc2ccc(cc12)C(=O)Nc1cccc(F)c1)C(O)=O Show InChI InChI=1S/C23H18ClFN2O7S/c1-33-19-8-6-14(24)10-21(19)35(31,32)27-12-20(23(29)30)34-18-7-5-13(9-17(18)27)22(28)26-16-4-2-3-15(25)11-16/h2-11,20H,12H2,1H3,(H,26,28)(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition of human CPT1B				J Med Chem 54: 3109-52 (2011) Article DOI: 10.1021/jm100809g BindingDB Entry DOI: 10.7270/Q29K4CDQ
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Homo sapiens (Human))	BDBM50403038 (CHEMBL2216777) Show SMILES COc1ccc(C)cc1S(=O)(=O)N1CCCc2ccc(cc12)C(=O)Nc1ccc(CC(O)=O)cc1 Show InChI InChI=1S/C26H26N2O6S/c1-17-5-12-23(34-2)24(14-17)35(32,33)28-13-3-4-19-8-9-20(16-22(19)28)26(31)27-21-10-6-18(7-11-21)15-25(29)30/h5-12,14,16H,3-4,13,15H2,1-2H3,(H,27,31)(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition of human CPT1B				J Med Chem 54: 3109-52 (2011) Article DOI: 10.1021/jm100809g BindingDB Entry DOI: 10.7270/Q29K4CDQ
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50101589 (CHEMBL77174 | [3-Carboxy-2-(nonylaminosulphonyl-am...) Show SMILES CCCCCCCCCNS(=O)(=O)NC(CC([O-])=O)C[N+](C)(C)C Show InChI InChI=1S/C16H35N3O4S/c1-5-6-7-8-9-10-11-12-17-24(22,23)18-15(13-16(20)21)14-19(2,3)4/h15,17-18H,5-14H2,1-4H3	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sigma Tau Pharmaceutical Industries S.p.A. Curated by ChEMBL					Assay Description Inhibitory activity against rat heart mitochondrial carnitine palmitoyltransferase 1b using [14C]-palmitoyl-CoA as radioligand				J Med Chem 44: 2383-6 (2001) BindingDB Entry DOI: 10.7270/Q2930SG7
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Homo sapiens (Human))	BDBM50122839 (CHEMBL106227 | [3-Carboxy-2-(3-tetradecyl-ureido)-...) Show SMILES CCCCCCCCCCCCCCNC(=O)N[C@H](CC([O-])=O)C[N+](C)(C)C Show InChI InChI=1S/C22H45N3O3/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-23-22(28)24-20(18-21(26)27)19-25(2,3)4/h20H,5-19H2,1-4H3,(H2-,23,24,26,27,28)/t20-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition of human CPT1B				J Med Chem 54: 3109-52 (2011) Article DOI: 10.1021/jm100809g BindingDB Entry DOI: 10.7270/Q29K4CDQ
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50101591 (CHEMBL308869 | R-[3-Carboxy-2-(undecane-1-sulfamoy...) Show SMILES CCCCCCCCCCCNS(=O)(=O)N[C@H](CC([O-])=O)C[N+](C)(C)C Show InChI InChI=1S/C18H39N3O4S/c1-5-6-7-8-9-10-11-12-13-14-19-26(24,25)20-17(15-18(22)23)16-21(2,3)4/h17,19-20H,5-16H2,1-4H3/t17-/m1/s1	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sigma Tau Pharmaceutical Industries S.p.A. Curated by ChEMBL					Assay Description Inhibitory activity against rat heart mitochondrial carnitine palmitoyltransferase 1b using [14C]-palmitoyl-CoA as radioligand				J Med Chem 44: 2383-6 (2001) BindingDB Entry DOI: 10.7270/Q2930SG7
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50101591 (CHEMBL308869 | R-[3-Carboxy-2-(undecane-1-sulfamoy...) Show SMILES CCCCCCCCCCCNS(=O)(=O)N[C@H](CC([O-])=O)C[N+](C)(C)C Show InChI InChI=1S/C18H39N3O4S/c1-5-6-7-8-9-10-11-12-13-14-19-26(24,25)20-17(15-18(22)23)16-21(2,3)4/h17,19-20H,5-16H2,1-4H3/t17-/m1/s1	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sigma Tau Pharmaceutical Industries S.p.A. Curated by ChEMBL					Assay Description In vitro inhibition of [14C]-palmitoyl-CoA and carnitine binding to carnitine palmitoyltransferase I of rat heart mitochondria				J Med Chem 46: 303-9 (2003) Article DOI: 10.1021/jm020979u BindingDB Entry DOI: 10.7270/Q2N015WM
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Homo sapiens (Human))	BDBM50403043 (CHEMBL2216780) Show SMILES OC(=O)c1ccc(NC(=O)c2cccc(NS(=O)(=O)c3ccc(Cl)c(Cl)c3)c2)cc1 Show InChI InChI=1S/C20H14Cl2N2O5S/c21-17-9-8-16(11-18(17)22)30(28,29)24-15-3-1-2-13(10-15)19(25)23-14-6-4-12(5-7-14)20(26)27/h1-11,24H,(H,23,25)(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition of human CPT1B				J Med Chem 54: 3109-52 (2011) Article DOI: 10.1021/jm100809g BindingDB Entry DOI: 10.7270/Q29K4CDQ
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50101604 (CHEMBL309568 | [3-Carboxy-2-(dodecane-1-sulfonylam...) Show SMILES CCCCCCCCCCCCS(=O)(=O)N[C@@H](CC([O-])=O)C[N+](C)(C)C Show InChI InChI=1S/C19H40N2O4S/c1-5-6-7-8-9-10-11-12-13-14-15-26(24,25)20-18(16-19(22)23)17-21(2,3)4/h18,20H,5-17H2,1-4H3/t18-/m0/s1	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sigma Tau Pharmaceutical Industries S.p.A. Curated by ChEMBL					Assay Description Inhibitory activity against rat heart mitochondrial carnitine palmitoyltransferase 1b using [14C]-palmitoyl-CoA as radioligand				J Med Chem 44: 2383-6 (2001) BindingDB Entry DOI: 10.7270/Q2930SG7
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50101598 (CHEMBL307495 | [3-Carboxy-2-(dodecane-1-sulfonylam...) Show SMILES CCCCCCCCCCCCS(=O)(=O)N[C@H](CC([O-])=O)C[N+](C)(C)C Show InChI InChI=1S/C19H40N2O4S/c1-5-6-7-8-9-10-11-12-13-14-15-26(24,25)20-18(16-19(22)23)17-21(2,3)4/h18,20H,5-17H2,1-4H3/t18-/m1/s1	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sigma Tau Pharmaceutical Industries S.p.A. Curated by ChEMBL					Assay Description In vitro inhibition of [14C]-palmitoyl-CoA and carnitine binding to carnitine palmitoyltransferase I of rat heart mitochondria				J Med Chem 46: 303-9 (2003) Article DOI: 10.1021/jm020979u BindingDB Entry DOI: 10.7270/Q2N015WM
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50101600 (CHEMBL305897 | [3-Carboxy-2-(undecane-1-sulfamoyla...) Show SMILES CCCCCCCCCCCNS(=O)(=O)N[C@@H](CC([O-])=O)C[N+](C)(C)C Show InChI InChI=1S/C18H39N3O4S/c1-5-6-7-8-9-10-11-12-13-14-19-26(24,25)20-17(15-18(22)23)16-21(2,3)4/h17,19-20H,5-16H2,1-4H3/t17-/m0/s1	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sigma Tau Pharmaceutical Industries S.p.A. Curated by ChEMBL					Assay Description In vitro inhibition of [14C]-palmitoyl-CoA and carnitine binding to carnitine palmitoyltransferase I of rat heart mitochondria				J Med Chem 46: 303-9 (2003) Article DOI: 10.1021/jm020979u BindingDB Entry DOI: 10.7270/Q2N015WM
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50101600 (CHEMBL305897 | [3-Carboxy-2-(undecane-1-sulfamoyla...) Show SMILES CCCCCCCCCCCNS(=O)(=O)N[C@@H](CC([O-])=O)C[N+](C)(C)C Show InChI InChI=1S/C18H39N3O4S/c1-5-6-7-8-9-10-11-12-13-14-19-26(24,25)20-17(15-18(22)23)16-21(2,3)4/h17,19-20H,5-16H2,1-4H3/t17-/m0/s1	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sigma Tau Pharmaceutical Industries S.p.A. Curated by ChEMBL					Assay Description Inhibitory activity against rat heart mitochondrial carnitine palmitoyltransferase 1b using [14C]-palmitoyl-CoA as radioligand				J Med Chem 44: 2383-6 (2001) BindingDB Entry DOI: 10.7270/Q2930SG7
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Homo sapiens (Human))	BDBM50118093 ((4-Hydroxy-phenyl)-oxo-acetic acid | CHEMBL129918) Show SMILES OC(=O)C(=O)c1ccc(O)cc1 Show InChI InChI=1S/C8H6O4/c9-6-3-1-5(2-4-6)7(10)8(11)12/h1-4,9H,(H,11,12)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition of CPT1B in heart mitochondria				J Med Chem 54: 3109-52 (2011) Article DOI: 10.1021/jm100809g BindingDB Entry DOI: 10.7270/Q29K4CDQ
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50260115 (CHEMBL4097976) Show SMILES C(C(C1CCCC1)C1CCCCC1)C1CCCCN1 Show InChI InChI=1S/C18H33N/c1-2-8-15(9-3-1)18(16-10-4-5-11-16)14-17-12-6-7-13-19-17/h15-19H,1-14H2	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kosterlitz Centre for Therapeutics, University of Aberdeen , Foresterhill, Aberdeen, AB25 2ZD, U.K. Curated by ChEMBL					Assay Description Inhibition of rat heart mitochondrial CPT-1				J Med Chem 60: 2780-2789 (2017) Article DOI: 10.1021/acs.jmedchem.6b01592 BindingDB Entry DOI: 10.7270/Q20867SV
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM61402 ((Z)-2-butenedioic acid;2-(2,2-dicyclohexylethyl)pi...) Show SMILES C(C(C1CCCCC1)C1CCCCC1)C1CCCCN1 Show InChI InChI=1S/C19H35N/c1-3-9-16(10-4-1)19(17-11-5-2-6-12-17)15-18-13-7-8-14-20-18/h16-20H,1-15H2	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kosterlitz Centre for Therapeutics, University of Aberdeen , Foresterhill, Aberdeen, AB25 2ZD, U.K. Curated by ChEMBL					Assay Description Inhibition of rat heart mitochondrial CPT-1				J Med Chem 60: 2780-2789 (2017) Article DOI: 10.1021/acs.jmedchem.6b01592 BindingDB Entry DOI: 10.7270/Q20867SV
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50260105 (CHEMBL1592481) Show SMILES C(C(C1CCCCC1)C1CCCCC1)[C@@H]1CCCCN1 Show InChI InChI=1S/C19H35N/c1-3-9-16(10-4-1)19(17-11-5-2-6-12-17)15-18-13-7-8-14-20-18/h16-20H,1-15H2/t18-/m0/s1	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kosterlitz Centre for Therapeutics, University of Aberdeen , Foresterhill, Aberdeen, AB25 2ZD, U.K. Curated by ChEMBL					Assay Description Inhibition of Wistar rat heart mitochondrial CPT-1 assessed as reduction in conversion of palmitoyl CoA and L-carnitine into palmitoylcarnitine prein...				J Med Chem 60: 2780-2789 (2017) Article DOI: 10.1021/acs.jmedchem.6b01592 BindingDB Entry DOI: 10.7270/Q20867SV
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50260109 (CHEMBL4077250) Show SMILES C(C(C1CCCC1)C1CCCC1)C1CCCCN1 Show InChI InChI=1S/C17H31N/c1-2-8-14(7-1)17(15-9-3-4-10-15)13-16-11-5-6-12-18-16/h14-18H,1-13H2	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kosterlitz Centre for Therapeutics, University of Aberdeen , Foresterhill, Aberdeen, AB25 2ZD, U.K. Curated by ChEMBL					Assay Description Inhibition of rat heart mitochondrial CPT-1				J Med Chem 60: 2780-2789 (2017) Article DOI: 10.1021/acs.jmedchem.6b01592 BindingDB Entry DOI: 10.7270/Q20867SV
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Homo sapiens (Human))	BDBM50403033 (CHEMBL1231507) Show SMILES CCCCCCCCCCCCCCCC(=O)N[C@H](CC([O-])=O)C[N+](C)(C)C |r| Show InChI InChI=1S/C23H46N2O3/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-22(26)24-21(19-23(27)28)20-25(2,3)4/h21H,5-20H2,1-4H3,(H-,24,26,27,28)/t21-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	2.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition of human CPT1B				J Med Chem 54: 3109-52 (2011) Article DOI: 10.1021/jm100809g BindingDB Entry DOI: 10.7270/Q29K4CDQ
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50403034 (CHEMBL2114397) Show SMILES C[N+](C)(C)C[C@H](N)CC([O-])=O |r| Show InChI InChI=1S/C7H16N2O2/c1-9(2,3)5-6(8)4-7(10)11/h6H,4-5,8H2,1-3H3/t6-/m1/s1	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.73E+4	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Maximal inhibition of rat CPT1A				J Med Chem 54: 3109-52 (2011) Article DOI: 10.1021/jm100809g BindingDB Entry DOI: 10.7270/Q29K4CDQ
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50260108 (CHEMBL4082420) Show SMILES C(C(C1CCCCC1)C1CCCCC1)[C@H]1CCCCN1 |r| Show InChI InChI=1S/C19H35N/c1-3-9-16(10-4-1)19(17-11-5-2-6-12-17)15-18-13-7-8-14-20-18/h16-20H,1-15H2/t18-/m1/s1	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kosterlitz Centre for Therapeutics, University of Aberdeen , Foresterhill, Aberdeen, AB25 2ZD, U.K. Curated by ChEMBL					Assay Description Inhibition of rat heart mitochondrial CPT-1				J Med Chem 60: 2780-2789 (2017) Article DOI: 10.1021/acs.jmedchem.6b01592 BindingDB Entry DOI: 10.7270/Q20867SV
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50122839 (CHEMBL106227 | [3-Carboxy-2-(3-tetradecyl-ureido)-...) Show SMILES CCCCCCCCCCCCCCNC(=O)N[C@H](CC([O-])=O)C[N+](C)(C)C Show InChI InChI=1S/C22H45N3O3/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-23-22(28)24-20(18-21(26)27)19-25(2,3)4/h20H,5-19H2,1-4H3,(H2-,23,24,26,27,28)/t20-/m1/s1	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	4.34E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sigma Tau Pharmaceutical Industries S.p.A. Curated by ChEMBL					Assay Description In vitro inhibition of [14C]-palmitoyl-CoA and carnitine binding to carnitine palmitoyltransferase I of rat heart mitochondria				J Med Chem 46: 303-9 (2003) Article DOI: 10.1021/jm020979u BindingDB Entry DOI: 10.7270/Q2N015WM
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50260104 (CHEMBL4081530) Show SMILES FC1(F)CCC(CC1)C(CC1CCCCN1)C1CCCCC1 Show InChI InChI=1S/C19H33F2N/c20-19(21)11-9-16(10-12-19)18(15-6-2-1-3-7-15)14-17-8-4-5-13-22-17/h15-18,22H,1-14H2	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kosterlitz Centre for Therapeutics, University of Aberdeen , Foresterhill, Aberdeen, AB25 2ZD, U.K. Curated by ChEMBL					Assay Description Inhibition of rat heart mitochondrial CPT-1				J Med Chem 60: 2780-2789 (2017) Article DOI: 10.1021/acs.jmedchem.6b01592 BindingDB Entry DOI: 10.7270/Q20867SV
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50122827 (CHEMBL105330 | [3-Carboxy-2-(3-nonyl-ureido)-propy...) Show SMILES CCCCCCCCCNC(=O)N[C@H](CC([O-])=O)C[N+](C)(C)C Show InChI InChI=1S/C17H35N3O3/c1-5-6-7-8-9-10-11-12-18-17(23)19-15(13-16(21)22)14-20(2,3)4/h15H,5-14H2,1-4H3,(H2-,18,19,21,22,23)/t15-/m1/s1	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.62E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sigma Tau Pharmaceutical Industries S.p.A. Curated by ChEMBL					Assay Description In vitro inhibition of [14C]-palmitoyl-CoA and carnitine binding to carnitine palmitoyltransferase I of rat heart mitochondria				J Med Chem 46: 303-9 (2003) Article DOI: 10.1021/jm020979u BindingDB Entry DOI: 10.7270/Q2N015WM
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Homo sapiens (Human))	BDBM50403030 (CHEMBL2216768) Show SMILES [O-]C(=O)C1(CO1)C(F)(F)CCCCCOc1ccc(Cl)cc1 Show InChI InChI=1S/C15H17ClF2O4/c16-11-4-6-12(7-5-11)21-9-3-1-2-8-15(17,18)14(10-22-14)13(19)20/h4-7H,1-3,8-10H2,(H,19,20)/p-1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition of CPT1B				J Med Chem 54: 3109-52 (2011) Article DOI: 10.1021/jm100809g BindingDB Entry DOI: 10.7270/Q29K4CDQ
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Homo sapiens (Human))	BDBM50118093 ((4-Hydroxy-phenyl)-oxo-acetic acid | CHEMBL129918) Show SMILES OC(=O)C(=O)c1ccc(O)cc1 Show InChI InChI=1S/C8H6O4/c9-6-3-1-5(2-4-6)7(10)8(11)12/h1-4,9H,(H,11,12)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition of human CPT1B				J Med Chem 54: 3109-52 (2011) Article DOI: 10.1021/jm100809g BindingDB Entry DOI: 10.7270/Q29K4CDQ
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50260105 (CHEMBL1592481) Show SMILES C(C(C1CCCCC1)C1CCCCC1)[C@@H]1CCCCN1 Show InChI InChI=1S/C19H35N/c1-3-9-16(10-4-1)19(17-11-5-2-6-12-17)15-18-13-7-8-14-20-18/h16-20H,1-15H2/t18-/m0/s1	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kosterlitz Centre for Therapeutics, University of Aberdeen , Foresterhill, Aberdeen, AB25 2ZD, U.K. Curated by ChEMBL					Assay Description Inhibition of rat heart mitochondrial CPT-1				J Med Chem 60: 2780-2789 (2017) Article DOI: 10.1021/acs.jmedchem.6b01592 BindingDB Entry DOI: 10.7270/Q20867SV
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50122833 ((3-Carboxy-2-octyloxycarbonylamino-propyl)-trimeth...) Show SMILES CCCCCCCCOC(=O)N[C@H](CC([O-])=O)C[N+](C)(C)C Show InChI InChI=1S/C16H32N2O4/c1-5-6-7-8-9-10-11-22-16(21)17-14(12-15(19)20)13-18(2,3)4/h14H,5-13H2,1-4H3,(H-,17,19,20,21)/t14-/m1/s1	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sigma Tau Pharmaceutical Industries S.p.A. Curated by ChEMBL					Assay Description In vitro inhibition of [14C]-palmitoyl-CoA and carnitine binding to carnitine palmitoyltransferase I of rat heart mitochondria				J Med Chem 46: 303-9 (2003) Article DOI: 10.1021/jm020979u BindingDB Entry DOI: 10.7270/Q2N015WM
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50101590 (CHEMBL78921 | [3-Carboxy-2-(3-nonyl-ureido)-propyl...) Show SMILES CCCCCCCCCNC(=O)NC(CC([O-])=O)C[N+](C)(C)C Show InChI InChI=1S/C17H35N3O3/c1-5-6-7-8-9-10-11-12-18-17(23)19-15(13-16(21)22)14-20(2,3)4/h15H,5-14H2,1-4H3,(H2-,18,19,21,22,23)	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.32E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sigma Tau Pharmaceutical Industries S.p.A. Curated by ChEMBL					Assay Description Inhibitory activity against rat heart mitochondrial carnitine palmitoyltransferase 1b using [14C]-palmitoyl-CoA as radioligand				J Med Chem 44: 2383-6 (2001) BindingDB Entry DOI: 10.7270/Q2930SG7
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Homo sapiens (Human))	BDBM50403032 (CHEMBL2216785) Show SMILES CCCCCCOc1cccc(OCCCCNC(=O)N[C@H](CC([O-])=O)C[N+](C)(C)C)c1 |r| Show InChI InChI=1S/C24H41N3O5/c1-5-6-7-9-15-31-21-12-11-13-22(18-21)32-16-10-8-14-25-24(30)26-20(17-23(28)29)19-27(2,3)4/h11-13,18,20H,5-10,14-17,19H2,1-4H3,(H2-,25,26,28,29,30)/t20-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition of human CPT1B				J Med Chem 54: 3109-52 (2011) Article DOI: 10.1021/jm100809g BindingDB Entry DOI: 10.7270/Q29K4CDQ
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Rattus norvegicus)	BDBM50260112 (CHEMBL4068222) Show SMILES FC1(F)CCC(CC1)C(CC1CCCCN1)C1CCC(F)(F)CC1 Show InChI InChI=1S/C19H31F4N/c20-18(21)8-4-14(5-9-18)17(13-16-3-1-2-12-24-16)15-6-10-19(22,23)11-7-15/h14-17,24H,1-13H2	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kosterlitz Centre for Therapeutics, University of Aberdeen , Foresterhill, Aberdeen, AB25 2ZD, U.K. Curated by ChEMBL					Assay Description Inhibition of rat heart mitochondrial CPT-1				J Med Chem 60: 2780-2789 (2017) Article DOI: 10.1021/acs.jmedchem.6b01592 BindingDB Entry DOI: 10.7270/Q20867SV
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Homo sapiens (Human))	BDBM61402 ((Z)-2-butenedioic acid;2-(2,2-dicyclohexylethyl)pi...) Show SMILES C(C(C1CCCCC1)C1CCCCC1)C1CCCCN1 Show InChI InChI=1S/C19H35N/c1-3-9-16(10-4-1)19(17-11-5-2-6-12-17)15-18-13-7-8-14-20-18/h16-20H,1-15H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition of human CPT1B				J Med Chem 54: 3109-52 (2011) Article DOI: 10.1021/jm100809g BindingDB Entry DOI: 10.7270/Q29K4CDQ
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Homo sapiens (Human))	BDBM50403042 (CHEMBL2216775) Show SMILES COc1ccc(cc1)-c1noc(n1)[C@H]1CCCCN1C(=O)COc1ccccc1 |r| Show InChI InChI=1S/C22H23N3O4/c1-27-17-12-10-16(11-13-17)21-23-22(29-24-21)19-9-5-6-14-25(19)20(26)15-28-18-7-3-2-4-8-18/h2-4,7-8,10-13,19H,5-6,9,14-15H2,1H3/t19-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition of human CPT1B				J Med Chem 54: 3109-52 (2011) Article DOI: 10.1021/jm100809g BindingDB Entry DOI: 10.7270/Q29K4CDQ
					More data for this Ligand-Target Pair
Carnitine O-palmitoyltransferase 1, muscle isoform (Homo sapiens (Human))	BDBM50403037 (CHEMBL2216774) Show SMILES O=C(COc1ccccc1)N1CCCC[C@@H]1c1nc(cs1)-c1ccccn1 |r| Show InChI InChI=1S/C21H21N3O2S/c25-20(14-26-16-8-2-1-3-9-16)24-13-7-5-11-19(24)21-23-18(15-27-21)17-10-4-6-12-22-17/h1-4,6,8-10,12,15,19H,5,7,11,13-14H2/t19-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition of human CPT1B				J Med Chem 54: 3109-52 (2011) Article DOI: 10.1021/jm100809g BindingDB Entry DOI: 10.7270/Q29K4CDQ
					More data for this Ligand-Target Pair

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