Found 132 hits Enz. Inhib. hit(s) with Target = 'Lysine-specific histone demethylase 2' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597540
(CHEMBL5201156) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597567
(CHEMBL5193019)Show SMILES COc1cccc(c1)-c1cc(F)c(cc1F)[C@H]1C[C@H]1N |r| | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597538
(CHEMBL5206551) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| 8.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific demethylase 5A
(Mus musculus (Mouse)) | BDBM124969
(US8765820, 6l)Show SMILES NC1CC1c1ccc(NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)COc2ccccc2)cc1 Show InChI InChI=1S/C28H28N4O3/c29-24-15-23(24)18-10-12-20(13-11-18)31-28(34)26(14-19-16-30-25-9-5-4-8-22(19)25)32-27(33)17-35-21-6-2-1-3-7-21/h1-13,16,23-24,26,30H,14-15,17,29H2,(H,31,34)(H,32,33) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Universita Degli Studi di Roma “La Sapienza”; Fondazione IEO; Universita Degli Studi di Pavia; Universita Degli Studi di Milano
US Patent
| Assay Description Human recombinant MAO A and MAO B were expressed in Pichia pastoris and purified as published (Binda C, et al., Proc. Natl. Acad. Sci. USA 100: 9750-... |
US Patent US8765820 (2014)
BindingDB Entry DOI: 10.7270/Q20P0XPN |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597536
(CHEMBL5206853) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 1B
(Mus musculus) | BDBM50346586
(CHEMBL1795981 | US8765820, 5a)Show InChI InChI=1S/C17H18N2O2/c18-16-10-15(16)13-6-8-14(9-7-13)19-17(20)21-11-12-4-2-1-3-5-12/h1-9,15-16H,10-11,18H2,(H,19,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant mouse LSD2 expressed in Escherichia coli using histone H3 peptide dimethylated at Lys4 as substrate by peroxidase-coupled a... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c00919 BindingDB Entry DOI: 10.7270/Q28K7DTB |
More data for this Ligand-Target Pair | |
Lysine-specific demethylase 5A
(Mus musculus (Mouse)) | BDBM50346586
(CHEMBL1795981 | US8765820, 5a)Show InChI InChI=1S/C17H18N2O2/c18-16-10-15(16)13-6-8-14(9-7-13)19-17(20)21-11-12-4-2-1-3-5-12/h1-9,15-16H,10-11,18H2,(H,19,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| US Patent
| 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Universita Degli Studi di Roma “La Sapienza”; Fondazione IEO; Universita Degli Studi di Pavia; Universita Degli Studi di Milano
US Patent
| Assay Description Human recombinant MAO A and MAO B were expressed in Pichia pastoris and purified as published (Binda C, et al., Proc. Natl. Acad. Sci. USA 100: 9750-... |
US Patent US8765820 (2014)
BindingDB Entry DOI: 10.7270/Q20P0XPN |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597542
(CHEMBL5201621) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific demethylase 5A
(Mus musculus (Mouse)) | BDBM50346864
(CHEMBL1797641 | CHEMBL3104337 | US8765820, 8)Show SMILES NC1CC1c1ccc(NC(=O)C(Cc2ccccc2)NC(=O)OCc2ccccc2)cc1 Show InChI InChI=1S/C26H27N3O3/c27-23-16-22(23)20-11-13-21(14-12-20)28-25(30)24(15-18-7-3-1-4-8-18)29-26(31)32-17-19-9-5-2-6-10-19/h1-14,22-24H,15-17,27H2,(H,28,30)(H,29,31) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| US Patent
| 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Universita Degli Studi di Roma “La Sapienza”; Fondazione IEO; Universita Degli Studi di Pavia; Universita Degli Studi di Milano
US Patent
| Assay Description Human recombinant MAO A and MAO B were expressed in Pichia pastoris and purified as published (Binda C, et al., Proc. Natl. Acad. Sci. USA 100: 9750-... |
US Patent US8765820 (2014)
BindingDB Entry DOI: 10.7270/Q20P0XPN |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597532
(CHEMBL5175250) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 2.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597565
(CHEMBL5195762) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 3.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50346864
(CHEMBL1797641 | CHEMBL3104337 | US8765820, 8)Show SMILES NC1CC1c1ccc(NC(=O)C(Cc2ccccc2)NC(=O)OCc2ccccc2)cc1 Show InChI InChI=1S/C26H27N3O3/c27-23-16-22(23)20-11-13-21(14-12-20)28-25(30)24(15-18-7-3-1-4-8-18)29-26(31)32-17-19-9-5-2-6-10-19/h1-14,22-24H,15-17,27H2,(H,28,30)(H,29,31) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Prefectural University of Medicine
Curated by ChEMBL
| Assay Description Inhibition of LSD2 |
J Med Chem 54: 8236-50 (2011)
Article DOI: 10.1021/jm201048w BindingDB Entry DOI: 10.7270/Q2D50NFR |
More data for this Ligand-Target Pair | |
Lysine-specific demethylase 5A
(Mus musculus (Mouse)) | BDBM124968
(US8765820, 6e)Show SMILES NC1CC1c1ccc(NC(=O)C(Cc2ccccc2)NC(=O)COc2ccccc2)cc1 Show InChI InChI=1S/C26H27N3O3/c27-23-16-22(23)19-11-13-20(14-12-19)28-26(31)24(15-18-7-3-1-4-8-18)29-25(30)17-32-21-9-5-2-6-10-21/h1-14,22-24H,15-17,27H2,(H,28,31)(H,29,30) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| 3.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Universita Degli Studi di Roma “La Sapienza”; Fondazione IEO; Universita Degli Studi di Pavia; Universita Degli Studi di Milano
US Patent
| Assay Description Human recombinant MAO A and MAO B were expressed in Pichia pastoris and purified as published (Binda C, et al., Proc. Natl. Acad. Sci. USA 100: 9750-... |
US Patent US8765820 (2014)
BindingDB Entry DOI: 10.7270/Q20P0XPN |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 1B
(Mus musculus) | BDBM50346864
(CHEMBL1797641 | CHEMBL3104337 | US8765820, 8)Show SMILES NC1CC1c1ccc(NC(=O)C(Cc2ccccc2)NC(=O)OCc2ccccc2)cc1 Show InChI InChI=1S/C26H27N3O3/c27-23-16-22(23)20-11-13-21(14-12-20)28-25(30)24(15-18-7-3-1-4-8-18)29-26(31)32-17-19-9-5-2-6-10-19/h1-14,22-24H,15-17,27H2,(H,28,30)(H,29,31) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant mouse LSD2 expressed in Escherichia coli using histone H3 peptide dimethylated at Lys4 as substrate by peroxidase-coupled a... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c00919 BindingDB Entry DOI: 10.7270/Q28K7DTB |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597544
(CHEMBL5182251) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 4.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597550
(CHEMBL5185051) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 5.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597528
(CHEMBL5197683) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 5.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 1B
(Mus musculus) | BDBM50346863
(CHEMBL1797640 | US8765820, 5b)Show InChI InChI=1S/C16H16N2O/c17-15-10-14(15)11-6-8-13(9-7-11)18-16(19)12-4-2-1-3-5-12/h1-9,14-15H,10,17H2,(H,18,19) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 6.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant mouse LSD2 expressed in Escherichia coli using histone H3 peptide dimethylated at Lys4 as substrate by peroxidase-coupled a... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c00919 BindingDB Entry DOI: 10.7270/Q28K7DTB |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50155579
(CHEMBL3546846)Show SMILES N[C@@H]1C[C@H]1c1ccc(NC(=O)c2ccccc2)cc1 |r| Show InChI InChI=1S/C16H16N2O/c17-15-10-14(15)11-6-8-13(9-7-11)18-16(19)12-4-2-1-3-5-12/h1-9,14-15H,10,17H2,(H,18,19)/t14-,15+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| 6.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02156 BindingDB Entry DOI: 10.7270/Q2154N4T |
More data for this Ligand-Target Pair | |
Lysine-specific demethylase 5A
(Mus musculus (Mouse)) | BDBM50346863
(CHEMBL1797640 | US8765820, 5b)Show InChI InChI=1S/C16H16N2O/c17-15-10-14(15)11-6-8-13(9-7-11)18-16(19)12-4-2-1-3-5-12/h1-9,14-15H,10,17H2,(H,18,19) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| US Patent
| 6.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Universita Degli Studi di Roma “La Sapienza”; Fondazione IEO; Universita Degli Studi di Pavia; Universita Degli Studi di Milano
US Patent
| Assay Description Human recombinant MAO A and MAO B were expressed in Pichia pastoris and purified as published (Binda C, et al., Proc. Natl. Acad. Sci. USA 100: 9750-... |
US Patent US8765820 (2014)
BindingDB Entry DOI: 10.7270/Q20P0XPN |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597548
(CHEMBL5179483) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 7.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597527
(CHEMBL5195724) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597568
(CHEMBL5173231)Show SMILES COc1cccc(c1)-c1cc(F)c(cc1F)[C@H]1C[C@@H]1N |r| | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 8.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597530
(CHEMBL5196391) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 8.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597537
(CHEMBL5176392) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 9.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597543
(CHEMBL5182939) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597541
(CHEMBL5196815) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597539
(CHEMBL5186086) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597564
(CHEMBL5201735) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597561
(CHEMBL5208295) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597560
(CHEMBL5194434) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597557
(CHEMBL5169738)Show SMILES N[C@H]1C[C@@H]1c1c(F)ccc(F)c1OCc1ccccc1 |r| | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597558
(CHEMBL5169580) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597553
(CHEMBL5195723) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 2.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50568522
(CHEMBL4864352)Show SMILES CN1CCN(CC1)C(=O)CNC1CC1c1cc(F)cc(F)c1OCc1ccccc1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >2.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of LSD2 (unknown origin) using Lys4-dimethylated H3 (1-20) peptide as substrate incubated for 30 mins by peroxidase-coupled assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c00919 BindingDB Entry DOI: 10.7270/Q28K7DTB |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50594951
(CHEMBL5174572)Show SMILES CN1CCN(CC1)C(=O)NC1CC1c1cc(F)cc(F)c1OCc1ccccc1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >2.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114143 BindingDB Entry DOI: 10.7270/Q28W3J9V |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597534
(CHEMBL5195836) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 2.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50346585
(CHEMBL1795980 | S2101)Show InChI InChI=1S/C16H15F2NO/c17-11-6-13(12-8-15(12)19)16(14(18)7-11)20-9-10-4-2-1-3-5-10/h1-7,12,15H,8-9,19H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >2.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of LSD2 (unknown origin) using Lys4-dimethylated H3 (1-20) peptide as substrate incubated for 30 mins by peroxidase-coupled assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c00919 BindingDB Entry DOI: 10.7270/Q28K7DTB |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50568521
(CHEMBL4878787)Show SMILES N[C@H]1CCN(C1)C(=O)CNC1CC1c1cc(F)cc(F)c1OCc1ccccc1 |r| | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >2.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of LSD2 (unknown origin) using Lys4-dimethylated H3 (1-20) peptide as substrate incubated for 30 mins by peroxidase-coupled assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c00919 BindingDB Entry DOI: 10.7270/Q28K7DTB |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597533
(CHEMBL5199765) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 2.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597529
(CHEMBL5204816) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 2.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597545
(CHEMBL5171748) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 2.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597531
(CHEMBL5204118) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 2.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597562
(CHEMBL5171751) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 2.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597552
(CHEMBL5193475) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 3.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597535
(CHEMBL5172958) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 3.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597547
(CHEMBL5177114)Show SMILES N[C@H]1C[C@@H]1c1c(F)cc(Br)cc1OCc1ccccc1 |r| | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 4.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597551
(CHEMBL5181893) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597549
(CHEMBL5187372) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 2
(Homo sapiens (Human)) | BDBM50597546
(CHEMBL5200774)Show SMILES N[C@@H]1C[C@@H]1c1c(F)cc(Br)cc1OCc1ccccc1 |r| | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00294 BindingDB Entry DOI: 10.7270/Q28S4TZ1 |
More data for this Ligand-Target Pair | |