Compile Data Set for Download or QSAR

Found 12 hits Enz. Inhib. hit(s) with Target = 'DNA primase' AND taxid = 10299   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA primase (Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)	BDBM50034949 (2-Amino-6-(3,5-dichloro-phenylamino)-3H-pyrimidin-...) Show SMILES Nc1nc(Nc2cc(Cl)cc(Cl)c2)cc(=O)[nH]1 Show InChI InChI=1S/C10H8Cl2N4O/c11-5-1-6(12)3-7(2-5)14-8-4-9(17)16-10(13)15-8/h1-4H,(H4,13,14,15,16,17)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
Stanford University Medical School Curated by ChEMBL					Assay Description Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cells				J Med Chem 38: 1820-5 (1995) BindingDB Entry DOI: 10.7270/Q29K4983
					More data for this Ligand-Target Pair
DNA primase (Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)	BDBM50034955 (CHEMBL53605 | N*2*-(3,4-Dichloro-phenyl)-9H-purine...) Show SMILES Nc1nc(Nc2ccc(Cl)c(Cl)c2)nc2nc[nH]c12 Show InChI InChI=1S/C11H8Cl2N6/c12-6-2-1-5(3-7(6)13)17-11-18-9(14)8-10(19-11)16-4-15-8/h1-4H,(H4,14,15,16,17,18,19)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
Stanford University Medical School Curated by ChEMBL					Assay Description Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cells				J Med Chem 38: 1820-5 (1995) BindingDB Entry DOI: 10.7270/Q29K4983
					More data for this Ligand-Target Pair
DNA primase (Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)	BDBM50034950 (2-Amino-6-(3,4-dichloro-phenylamino)-3H-pyrimidin-...) Show SMILES Nc1nc(Nc2ccc(Cl)c(Cl)c2)cc(=O)[nH]1 Show InChI InChI=1S/C10H8Cl2N4O/c11-6-2-1-5(3-7(6)12)14-8-4-9(17)16-10(13)15-8/h1-4H,(H4,13,14,15,16,17)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
Stanford University Medical School Curated by ChEMBL					Assay Description Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cells				J Med Chem 38: 1820-5 (1995) BindingDB Entry DOI: 10.7270/Q29K4983
					More data for this Ligand-Target Pair
DNA primase (Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)	BDBM50013091 (2-(3,4-Dichloro-phenylamino)-1,9-dihydro-purin-6-o...) Show SMILES Clc1ccc(Nc2nc3nc[nH]c3c(=O)[nH]2)cc1Cl Show InChI InChI=1S/C11H7Cl2N5O/c12-6-2-1-5(3-7(6)13)16-11-17-9-8(10(19)18-11)14-4-15-9/h1-4H,(H3,14,15,16,17,18,19)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
Stanford University Medical School Curated by ChEMBL					Assay Description Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cells				J Med Chem 38: 1820-5 (1995) BindingDB Entry DOI: 10.7270/Q29K4983
					More data for this Ligand-Target Pair
DNA primase (Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)	BDBM50034947 (2-(3,5-Dichloro-phenylamino)-1,9-dihydro-purin-6-o...) Show SMILES Clc1cc(Cl)cc(Nc2nc3nc[nH]c3c(=O)[nH]2)c1 Show InChI InChI=1S/C11H7Cl2N5O/c12-5-1-6(13)3-7(2-5)16-11-17-9-8(10(19)18-11)14-4-15-9/h1-4H,(H3,14,15,16,17,18,19)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	910	n/a	n/a	n/a	n/a	n/a	n/a
Stanford University Medical School Curated by ChEMBL					Assay Description Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cells				J Med Chem 38: 1820-5 (1995) BindingDB Entry DOI: 10.7270/Q29K4983
					More data for this Ligand-Target Pair
DNA primase (Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)	BDBM50034963 (CHEMBL51501 | N*2*-(3,5-Dichloro-phenyl)-9H-purine...) Show SMILES Nc1nc(Nc2cc(Cl)cc(Cl)c2)nc2nc[nH]c12 Show InChI InChI=1S/C11H8Cl2N6/c12-5-1-6(13)3-7(2-5)17-11-18-9(14)8-10(19-11)16-4-15-8/h1-4H,(H4,14,15,16,17,18,19)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	920	n/a	n/a	n/a	n/a	n/a	n/a
Stanford University Medical School Curated by ChEMBL					Assay Description Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cells				J Med Chem 38: 1820-5 (1995) BindingDB Entry DOI: 10.7270/Q29K4983
					More data for this Ligand-Target Pair
DNA primase (Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)	BDBM50034952 (6-(3,5-Dichloro-phenylamino)-1H-pyrimidine-2,4-dio...) Show SMILES Clc1cc(Cl)cc(Nc2cc(=O)[nH]c(=O)[nH]2)c1 Show InChI InChI=1S/C10H7Cl2N3O2/c11-5-1-6(12)3-7(2-5)13-8-4-9(16)15-10(17)14-8/h1-4H,(H3,13,14,15,16,17)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Stanford University Medical School Curated by ChEMBL					Assay Description Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cells				J Med Chem 38: 1820-5 (1995) BindingDB Entry DOI: 10.7270/Q29K4983
					More data for this Ligand-Target Pair
DNA primase (Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)	BDBM50028342 (6-(3,4-Dichloro-phenylamino)-1H-pyrimidine-2,4-dio...) Show SMILES Clc1ccc(Nc2cc(=O)[nH]c(=O)[nH]2)cc1Cl Show InChI InChI=1S/C10H7Cl2N3O2/c11-6-2-1-5(3-7(6)12)13-8-4-9(16)15-10(17)14-8/h1-4H,(H3,13,14,15,16,17)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Stanford University Medical School Curated by ChEMBL					Assay Description Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cells				J Med Chem 38: 1820-5 (1995) BindingDB Entry DOI: 10.7270/Q29K4983
					More data for this Ligand-Target Pair
DNA primase (Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)	BDBM50034961 (6-Chloro-N*4*-(3,4-dichloro-phenyl)-pyrimidine-2,4...) Show SMILES Nc1nc(Cl)cc(Nc2ccc(Cl)c(Cl)c2)n1 Show InChI InChI=1S/C10H7Cl3N4/c11-6-2-1-5(3-7(6)12)15-9-4-8(13)16-10(14)17-9/h1-4H,(H3,14,15,16,17)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Stanford University Medical School Curated by ChEMBL					Assay Description Inhibition against Primase by coupled primase-DNA polymerase-I assay with the two subunit recombinant HSV-1 helicase primase				J Med Chem 38: 1820-5 (1995) BindingDB Entry DOI: 10.7270/Q29K4983
					More data for this Ligand-Target Pair
DNA primase (Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)	BDBM50034955 (CHEMBL53605 | N*2*-(3,4-Dichloro-phenyl)-9H-purine...) Show SMILES Nc1nc(Nc2ccc(Cl)c(Cl)c2)nc2nc[nH]c12 Show InChI InChI=1S/C11H8Cl2N6/c12-6-2-1-5(3-7(6)13)17-11-18-9(14)8-10(19-11)16-4-15-8/h1-4H,(H4,14,15,16,17,18,19)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Stanford University Medical School Curated by ChEMBL					Assay Description Inhibition against Primase by coupled primase-DNA polymerase-I assay with the two subunit recombinant HSV-1 helicase primase				J Med Chem 38: 1820-5 (1995) BindingDB Entry DOI: 10.7270/Q29K4983
					More data for this Ligand-Target Pair
DNA primase (Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)	BDBM50013091 (2-(3,4-Dichloro-phenylamino)-1,9-dihydro-purin-6-o...) Show SMILES Clc1ccc(Nc2nc3nc[nH]c3c(=O)[nH]2)cc1Cl Show InChI InChI=1S/C11H7Cl2N5O/c12-6-2-1-5(3-7(6)13)16-11-17-9-8(10(19)18-11)14-4-15-9/h1-4H,(H3,14,15,16,17,18,19)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Stanford University Medical School Curated by ChEMBL					Assay Description Inhibition against Primase by coupled primase-DNA polymerase-I assay with the two subunit recombinant HSV-1 helicase primase				J Med Chem 38: 1820-5 (1995) BindingDB Entry DOI: 10.7270/Q29K4983
					More data for this Ligand-Target Pair
DNA primase (Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)	BDBM50137912 ((Biphenyl-4-sulfinyl)-acetic acid | (Biphenyl-4-su...) Show SMILES OC(=O)CS(=O)(=O)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C14H12O4S/c15-14(16)10-19(17,18)13-8-6-12(7-9-13)11-4-2-1-3-5-11/h1-9H,10H2,(H,15,16)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim (Canada) Ltd. Curated by ChEMBL					Assay Description Inhibitory concentration against herpes simplex virus helicase primase 8 (HSV)				J Med Chem 47: 18-21 (2003) Article DOI: 10.1021/jm034206x BindingDB Entry DOI: 10.7270/Q23F4P2Q
					More data for this Ligand-Target Pair