Compile Data Set for Download or QSAR

Found 10 hits Enz. Inhib. hit(s) with Target = 'Thymidine phosphorylase' AND taxid = 10116   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thymidine phosphorylase (Rattus norvegicus)	BDBM50378690 (CHEMBL597306) Show SMILES Cc1cn([C@@H]2CN(C[C@@H]2O)C(=O)P(O)(O)=O)c(=O)[nH]c1=O |r| Show InChI InChI=1S/C10H14N3O7P/c1-5-2-13(9(16)11-8(5)15)6-3-12(4-7(6)14)10(17)21(18,19)20/h2,6-7,14H,3-4H2,1H3,(H,11,15,16)(H2,18,19,20)/t6-,7+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphate				Bioorg Med Chem Lett 20: 862-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.081 BindingDB Entry DOI: 10.7270/Q2930V4K
					More data for this Ligand-Target Pair
Thymidine phosphorylase (Rattus norvegicus)	BDBM50378691 (CHEMBL609919) Show SMILES Cc1cn([C@@H]2CN(C[C@@H]2O)C(=S)P(O)(O)=O)c(=O)[nH]c1=O |r| Show InChI InChI=1S/C10H14N3O6PS/c1-5-2-13(9(16)11-8(5)15)6-3-12(4-7(6)14)10(21)20(17,18)19/h2,6-7,14H,3-4H2,1H3,(H,11,15,16)(H2,17,18,19)/t6-,7+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphate				Bioorg Med Chem Lett 20: 862-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.081 BindingDB Entry DOI: 10.7270/Q2930V4K
					More data for this Ligand-Target Pair
Thymidine phosphorylase (Rattus norvegicus)	BDBM50378689 (CHEMBL599563) Show SMILES Cc1cn([C@@H]2CN(CP(O)(O)=O)C[C@@H]2O)c(=O)[nH]c1=O |r| Show InChI InChI=1S/C10H16N3O6P/c1-6-2-13(10(16)11-9(6)15)7-3-12(4-8(7)14)5-20(17,18)19/h2,7-8,14H,3-5H2,1H3,(H,11,15,16)(H2,17,18,19)/t7-,8+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphate				Bioorg Med Chem Lett 20: 862-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.081 BindingDB Entry DOI: 10.7270/Q2930V4K
					More data for this Ligand-Target Pair
Thymidine phosphorylase (Rattus norvegicus)	BDBM50378684 (CHEMBL599543) Show SMILES Cc1cn([C@H]2C[C@H](CO)N(C2)C(=O)P(O)(O)=O)c(=O)[nH]c1=O |r| Show InChI InChI=1S/C11H16N3O7P/c1-6-3-13(10(17)12-9(6)16)7-2-8(5-15)14(4-7)11(18)22(19,20)21/h3,7-8,15H,2,4-5H2,1H3,(H,12,16,17)(H2,19,20,21)/t7-,8+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphate				Bioorg Med Chem Lett 20: 862-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.081 BindingDB Entry DOI: 10.7270/Q2930V4K
					More data for this Ligand-Target Pair
Thymidine phosphorylase (Rattus norvegicus)	BDBM50378687 (CHEMBL598328) Show SMILES Cc1cn(C2CCN(C2)C(=S)P(O)(O)=O)c(=O)[nH]c1=O Show InChI InChI=1S/C10H14N3O5PS/c1-6-4-13(9(15)11-8(6)14)7-2-3-12(5-7)10(20)19(16,17)18/h4,7H,2-3,5H2,1H3,(H,11,14,15)(H2,16,17,18)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphate				Bioorg Med Chem Lett 20: 862-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.081 BindingDB Entry DOI: 10.7270/Q2930V4K
					More data for this Ligand-Target Pair
Thymidine phosphorylase (Rattus norvegicus)	BDBM50378688 (CHEMBL599562) Show SMILES Cc1cn([C@@H]2CN(C[C@H]2O)C(=O)P(O)(O)=O)c(=O)[nH]c1=O |r| Show InChI InChI=1S/C10H14N3O7P/c1-5-2-13(9(16)11-8(5)15)6-3-12(4-7(6)14)10(17)21(18,19)20/h2,6-7,14H,3-4H2,1H3,(H,11,15,16)(H2,18,19,20)/t6-,7-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphate				Bioorg Med Chem Lett 20: 862-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.081 BindingDB Entry DOI: 10.7270/Q2930V4K
					More data for this Ligand-Target Pair
Thymidine phosphorylase (Rattus norvegicus)	BDBM50378685 (CHEMBL599544) Show SMILES Cc1cn([C@H]2C[C@H](CO)N(CP(O)(O)=O)C2)c(=O)[nH]c1=O |r| Show InChI InChI=1S/C11H18N3O6P/c1-7-3-14(11(17)12-10(7)16)8-2-9(5-15)13(4-8)6-21(18,19)20/h3,8-9,15H,2,4-6H2,1H3,(H,12,16,17)(H2,18,19,20)/t8-,9+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphate				Bioorg Med Chem Lett 20: 862-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.081 BindingDB Entry DOI: 10.7270/Q2930V4K
					More data for this Ligand-Target Pair
Thymidine phosphorylase (Rattus norvegicus)	BDBM50378692 (CHEMBL611383) Show SMILES Cc1cn(CC(OCC=C)OCP(O)(O)=O)c(=O)[nH]c1=O Show InChI InChI=1S/C11H17N2O7P/c1-3-4-19-9(20-7-21(16,17)18)6-13-5-8(2)10(14)12-11(13)15/h3,5,9H,1,4,6-7H2,2H3,(H,12,14,15)(H2,16,17,18)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphate				Bioorg Med Chem Lett 20: 862-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.081 BindingDB Entry DOI: 10.7270/Q2930V4K
					More data for this Ligand-Target Pair
Thymidine phosphorylase (Rattus norvegicus)	BDBM50378686 (CHEMBL598327) Show SMILES Cc1cn(C2CCN(C2)C(=O)P(O)(O)=O)c(=O)[nH]c1=O Show InChI InChI=1S/C10H14N3O6P/c1-6-4-13(9(15)11-8(6)14)7-2-3-12(5-7)10(16)20(17,18)19/h4,7H,2-3,5H2,1H3,(H,11,14,15)(H2,17,18,19)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphate				Bioorg Med Chem Lett 20: 862-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.081 BindingDB Entry DOI: 10.7270/Q2930V4K
					More data for this Ligand-Target Pair
Thymidine phosphorylase (Rattus norvegicus)	BDBM50378683 (CHEMBL599132) Show SMILES Cc1cn(CC(OCP(O)(O)=O)Oc2ccccc2)c(=O)[nH]c1=O Show InChI InChI=1S/C14H17N2O7P/c1-10-7-16(14(18)15-13(10)17)8-12(22-9-24(19,20)21)23-11-5-3-2-4-6-11/h2-7,12H,8-9H2,1H3,(H,15,17,18)(H2,19,20,21)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphate				Bioorg Med Chem Lett 20: 862-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.081 BindingDB Entry DOI: 10.7270/Q2930V4K
					More data for this Ligand-Target Pair