Compile Data Set for Download or QSAR

Found 50 hits Enz. Inhib. hit(s) with all data for entry = 6660   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144227 (US8952008, 4) Show SMILES CCn1cnc2c(cnnc12)-c1ccc(F)c(c1)-c1ccc(cc1OC)S(=O)(=O)CC Show InChI InChI=1S/C22H21FN4O3S/c1-4-27-13-24-21-18(12-25-26-22(21)27)14-6-9-19(23)17(10-14)16-8-7-15(11-20(16)30-3)31(28,29)5-2/h6-13H,4-5H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	<2.47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144226 (US8952008, 3) Show SMILES CCn1cnc2c(cnnc12)-c1ccc(F)c(c1)-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C19H16FN5O2S/c1-2-25-11-22-18-16(10-23-24-19(18)25)13-5-8-17(20)15(9-13)12-3-6-14(7-4-12)28(21,26)27/h3-11H,2H2,1H3,(H2,21,26,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.08	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144239 (US8952008, 32) Show SMILES CC(C)n1cnc2c(cnnc12)-c1ccc(F)c(c1)-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C20H18FN5O2S/c1-12(2)26-11-23-19-17(10-24-25-20(19)26)14-5-8-18(21)16(9-14)13-3-6-15(7-4-13)29(22,27)28/h3-12H,1-2H3,(H2,22,27,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.82	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144252 (US8952008, 8) Show SMILES CCn1cnc2c(cnnc12)-c1ccc(F)c(c1)-c1ccc(cc1)S(=O)(=O)NC Show InChI InChI=1S/C20H18FN5O2S/c1-3-26-12-23-19-17(11-24-25-20(19)26)14-6-9-18(21)16(10-14)13-4-7-15(8-5-13)29(27,28)22-2/h4-12,22H,3H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7.45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144256 (US8952008, 12) Show SMILES CCn1cnc2c(cnnc12)-c1ccc(F)c(c1)-c1ccc(cc1OC)S(C)(=O)=O Show InChI InChI=1S/C21H19FN4O3S/c1-4-26-12-23-20-17(11-24-25-21(20)26)13-5-8-18(22)16(9-13)15-7-6-14(30(3,27)28)10-19(15)29-2/h5-12H,4H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7.48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144270 (US8952008, 38) Show SMILES COc1cc(ccc1-c1cc(ccc1F)-c1cnnc2n(cnc12)C(C)C)S(C)(=O)=O Show InChI InChI=1S/C22H21FN4O3S/c1-13(2)27-12-24-21-18(11-25-26-22(21)27)14-5-8-19(23)17(9-14)16-7-6-15(31(4,28)29)10-20(16)30-3/h5-13H,1-4H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	8.56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144229 (US8952008, 6) Show SMILES CCn1cnc2c(cnnc12)-c1ccc(F)c(c1)-c1ccc(cc1OC)S(=O)(=O)C1CCC1 Show InChI InChI=1S/C24H23FN4O3S/c1-3-29-14-26-23-20(13-27-28-24(23)29)15-7-10-21(25)19(11-15)18-9-8-17(12-22(18)32-2)33(30,31)16-5-4-6-16/h7-14,16H,3-6H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	9.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144230 (US8952008, 7) Show SMILES CCn1cnc2c(cnnc12)-c1ccc(F)c(c1)-c1ccc(cc1OC)S(=O)(=O)C1CC1 Show InChI InChI=1S/C23H21FN4O3S/c1-3-28-13-25-22-19(12-26-27-23(22)28)14-4-9-20(24)18(10-14)17-8-7-16(11-21(17)31-2)32(29,30)15-5-6-15/h4,7-13,15H,3,5-6H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	9.71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144225 (US8952008, 2) Show SMILES CCn1cnc2c(cnnc12)-c1ccc(F)c(c1)-c1ccc(cc1F)S(C)(=O)=O Show InChI InChI=1S/C20H16F2N4O2S/c1-3-26-11-23-19-16(10-24-25-20(19)26)12-4-7-17(21)15(8-12)14-6-5-13(9-18(14)22)29(2,27)28/h4-11H,3H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	10.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144257 (US8952008, 13) Show SMILES CCn1cnc2c(cnnc12)-c1ccc(F)c(c1)-c1ccc(cc1OC)S(=O)(=O)C(C)C Show InChI InChI=1S/C23H23FN4O3S/c1-5-28-13-25-22-19(12-26-27-23(22)28)15-6-9-20(24)18(10-15)17-8-7-16(11-21(17)31-4)32(29,30)14(2)3/h6-14H,5H2,1-4H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	11.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144272 (US8952008, 40) Show SMILES CCS(=O)(=O)c1ccc(c(OC)c1)-c1cc(ccc1F)-c1cnnc2n(cnc12)C(C)C Show InChI InChI=1S/C23H23FN4O3S/c1-5-32(29,30)16-7-8-17(21(11-16)31-4)18-10-15(6-9-20(18)24)19-12-26-27-23-22(19)25-13-28(23)14(2)3/h6-14H,5H2,1-4H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144271 (US8952008, 39) Show SMILES CCS(=O)(=O)c1ccc(c(Cl)c1)-c1cc(ccc1F)-c1cnnc2n(cnc12)C(C)C Show InChI InChI=1S/C22H20ClFN4O2S/c1-4-31(29,30)15-6-7-16(19(23)10-15)17-9-14(5-8-20(17)24)18-11-26-27-22-21(18)25-12-28(22)13(2)3/h5-13H,4H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	14.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144240 (US8952008, 33) Show SMILES CNS(=O)(=O)c1ccc(cc1)-c1cc(ccc1F)-c1cnnc2n(cnc12)C(C)C Show InChI InChI=1S/C21H20FN5O2S/c1-13(2)27-12-24-20-18(11-25-26-21(20)27)15-6-9-19(22)17(10-15)14-4-7-16(8-5-14)30(28,29)23-3/h4-13,23H,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	16.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144253 (US8952008, 9) Show SMILES CCn1cnc2c(cnnc12)-c1ccc(F)c(c1)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C20H17FN4O2S/c1-3-25-12-22-19-17(11-23-24-20(19)25)14-6-9-18(21)16(10-14)13-4-7-15(8-5-13)28(2,26)27/h4-12H,3H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	17.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144259 (US8952008, 15) Show SMILES CCn1cnc2c(cnnc12)-c1ccc(F)c(c1)-c1ccc(cc1F)S(=O)(=O)CC Show InChI InChI=1S/C21H18F2N4O2S/c1-3-27-12-24-20-17(11-25-26-21(20)27)13-5-8-18(22)16(9-13)15-7-6-14(10-19(15)23)30(28,29)4-2/h5-12H,3-4H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	18.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144262 (US8952008, 20) Show SMILES CNS(=O)(=O)c1ccc(cc1)-c1cc(ccc1F)-c1cnnc2n(cnc12)C1CC1 Show InChI InChI=1S/C21H18FN5O2S/c1-23-30(28,29)16-7-2-13(3-8-16)17-10-14(4-9-19(17)22)18-11-25-26-21-20(18)24-12-27(21)15-5-6-15/h2-4,7-12,15,23H,5-6H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144269 (US8952008, 37) Show SMILES COc1cc(ccc1-c1cc(ccc1F)-c1cnnc2n(cnc12)C(C)C)S(=O)(=O)C(C)C Show InChI InChI=1S/C24H25FN4O3S/c1-14(2)29-13-26-23-20(12-27-28-24(23)29)16-6-9-21(25)19(10-16)18-8-7-17(11-22(18)32-5)33(30,31)15(3)4/h6-15H,1-5H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	19.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144250 (US8952008, 49) Show SMILES CCn1cnc2c(cnnc12)-c1ccc(F)c(c1)-c1ccc(cc1)S(=O)(=O)CC Show InChI InChI=1S/C21H19FN4O2S/c1-3-26-13-23-20-18(12-24-25-21(20)26)15-7-10-19(22)17(11-15)14-5-8-16(9-6-14)29(27,28)4-2/h5-13H,3-4H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	21.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144238 (US8952008, 31) Show SMILES CCS(=O)(=O)c1ccc(cc1)-c1cc(ccc1F)-c1cnnc2n(cnc12)C(C)C Show InChI InChI=1S/C22H21FN4O2S/c1-4-30(28,29)17-8-5-15(6-9-17)18-11-16(7-10-20(18)23)19-12-25-26-22-21(19)24-13-27(22)14(2)3/h5-14H,4H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	23.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144273 (US8952008, 41) Show SMILES CCS(=O)(=O)c1ccc(c(c1)C#N)-c1cc(ccc1F)-c1cnnc2n(cnc12)C(C)C Show InChI InChI=1S/C23H20FN5O2S/c1-4-32(30,31)17-6-7-18(16(9-17)11-25)19-10-15(5-8-21(19)24)20-12-27-28-23-22(20)26-13-29(23)14(2)3/h5-10,12-14H,4H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	29.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144246 (US8952008, 45) Show SMILES CCn1cnc2c(cnnc12)-c1ccc(Cl)c(c1)-c1ccc(cc1OC)S(=O)(=O)CC Show InChI InChI=1S/C22H21ClN4O3S/c1-4-27-13-24-21-18(12-25-26-22(21)27)14-6-9-19(23)17(10-14)16-8-7-15(11-20(16)30-3)31(28,29)5-2/h6-13H,4-5H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	29.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144232 (US8952008, 19) Show SMILES CCS(=O)(=O)c1ccc(cc1)-c1cc(ccc1F)-c1cnnc2n(cnc12)C1CC1 Show InChI InChI=1S/C22H19FN4O2S/c1-2-30(28,29)17-8-3-14(4-9-17)18-11-15(5-10-20(18)23)19-12-25-26-22-21(19)24-13-27(22)16-6-7-16/h3-5,8-13,16H,2,6-7H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	31.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144224 (US8952008, 1) Show SMILES CCn1cnc2c(cnnc12)-c1ccc(F)c(c1)-c1ccc(cc1)S(=O)(=O)C(C)C Show InChI InChI=1S/C22H21FN4O2S/c1-4-27-13-24-21-19(12-25-26-22(21)27)16-7-10-20(23)18(11-16)15-5-8-17(9-6-15)30(28,29)14(2)3/h5-14H,4H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	31.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144241 (US8952008, 34) Show SMILES CCS(=O)(=O)c1ccc(c(F)c1)-c1cc(ccc1F)-c1cnnc2n(cnc12)C(C)C Show InChI InChI=1S/C22H20F2N4O2S/c1-4-31(29,30)15-6-7-16(20(24)10-15)17-9-14(5-8-19(17)23)18-11-26-27-22-21(18)25-12-28(22)13(2)3/h5-13H,4H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	34.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144234 (US8952008, 27) Show SMILES CCS(=O)(=O)c1ccc(cc1)-c1cc(ccc1F)-c1cnnc2n(cnc12)C1(C)CC1 Show InChI InChI=1S/C23H21FN4O2S/c1-3-31(29,30)17-7-4-15(5-8-17)18-12-16(6-9-20(18)24)19-13-26-27-22-21(19)25-14-28(22)23(2)10-11-23/h4-9,12-14H,3,10-11H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	34.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144258 (US8952008, 14) Show SMILES CCn1cnc2c(cnnc12)-c1ccc(F)c(c1)-c1ccc(cc1C(F)F)S(=O)(=O)CC Show InChI InChI=1S/C22H19F3N4O2S/c1-3-29-12-26-20-18(11-27-28-22(20)29)13-5-8-19(23)16(9-13)15-7-6-14(32(30,31)4-2)10-17(15)21(24)25/h5-12,21H,3-4H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	35.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144266 (US8952008, 24) Show SMILES COc1cc(ccc1-c1cc(ccc1F)-c1cnnc2n(cnc12)C1CC1)S(C)(=O)=O Show InChI InChI=1S/C22H19FN4O3S/c1-30-20-10-15(31(2,28)29)6-7-16(20)17-9-13(3-8-19(17)23)18-11-25-26-22-21(18)24-12-27(22)14-4-5-14/h3,6-12,14H,4-5H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	37.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144242 (US8952008, 35) Show SMILES CC(C)n1cnc2c(cnnc12)-c1ccc(F)c(c1)-c1ccc(cc1C#N)S(=O)(=O)C(C)C Show InChI InChI=1S/C24H22FN5O2S/c1-14(2)30-13-27-23-21(12-28-29-24(23)30)16-5-8-22(25)20(10-16)19-7-6-18(9-17(19)11-26)33(31,32)15(3)4/h5-10,12-15H,1-4H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	38.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144255 (US8952008, 11) Show SMILES CCn1cnc2c(cnnc12)-c1ccc(F)c(c1)-c1ccc(cc1C#N)S(=O)(=O)CC Show InChI InChI=1S/C22H18FN5O2S/c1-3-28-13-25-21-19(12-26-27-22(21)28)14-5-8-20(23)18(10-14)17-7-6-16(9-15(17)11-24)31(29,30)4-2/h5-10,12-13H,3-4H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	39.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144265 (US8952008, 23) Show SMILES COc1cc(ccc1-c1cc(ccc1F)-c1cnnc2n(cnc12)C1CC1)S(=O)(=O)C(C)C Show InChI InChI=1S/C24H23FN4O3S/c1-14(2)33(30,31)17-7-8-18(22(11-17)32-3)19-10-15(4-9-21(19)25)20-12-27-28-24-23(20)26-13-29(24)16-5-6-16/h4,7-14,16H,5-6H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	40.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144248 (US8952008, 47) Show SMILES CCn1cnc2c(cnnc12)-c1ccc([N+]#[C-])c(c1)-c1ccc(cc1OC)S(=O)(=O)CC Show InChI InChI=1S/C23H21N5O3S/c1-5-28-14-25-22-19(13-26-27-23(22)28)15-7-10-20(24-3)18(11-15)17-9-8-16(12-21(17)31-4)32(29,30)6-2/h7-14H,5-6H2,1-2,4H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	40.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144263 (US8952008, 21) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cc(ccc1F)-c1cnnc2n(cnc12)C1CC1 Show InChI InChI=1S/C21H17FN4O2S/c1-29(27,28)16-7-2-13(3-8-16)17-10-14(4-9-19(17)22)18-11-24-25-21-20(18)23-12-26(21)15-5-6-15/h2-4,7-12,15H,5-6H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	43.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144260 (US8952008, 16) Show SMILES CCn1cnc2c(cnnc12)-c1cccc(c1)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C20H18N4O2S/c1-3-24-13-21-19-18(12-22-23-20(19)24)16-6-4-5-15(11-16)14-7-9-17(10-8-14)27(2,25)26/h4-13H,3H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144254 (US8952008, 10) Show SMILES CCn1cnc2c(cnnc12)-c1ccc(F)c(c1)-c1ccc(cc1F)S(=O)(=O)C(C)C Show InChI InChI=1S/C22H20F2N4O2S/c1-4-28-12-25-21-18(11-26-27-22(21)28)14-5-8-19(23)17(9-14)16-7-6-15(10-20(16)24)31(29,30)13(2)3/h5-13H,4H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	61.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144264 (US8952008, 22) Show SMILES CCS(=O)(=O)c1ccc(c(F)c1)-c1cc(ccc1F)-c1cnnc2n(cnc12)C1CC1 Show InChI InChI=1S/C22H18F2N4O2S/c1-2-31(29,30)15-6-7-16(20(24)10-15)17-9-13(3-8-19(17)23)18-11-26-27-22-21(18)25-12-28(22)14-4-5-14/h3,6-12,14H,2,4-5H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	67.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144251 (US8952008, 50) Show SMILES CCn1cnc2c(cnnc12)-c1ccc(F)c(c1)-c1ccc2c(CC(C)S2(=O)=O)c1 Show InChI InChI=1S/C22H19FN4O2S/c1-3-27-12-24-21-18(11-25-26-22(21)27)15-4-6-19(23)17(10-15)14-5-7-20-16(9-14)8-13(2)30(20,28)29/h4-7,9-13H,3,8H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	69.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144235 (US8952008, 28) Show SMILES CCS(=O)(=O)c1ccc(cc1)-c1cc(ccc1F)-c1cnnc2n(cnc12)C1CCC1 Show InChI InChI=1S/C23H21FN4O2S/c1-2-31(29,30)18-9-6-15(7-10-18)19-12-16(8-11-21(19)24)20-13-26-27-23-22(20)25-14-28(23)17-4-3-5-17/h6-14,17H,2-5H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	74.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144268 (US8952008, 36) Show SMILES CC(C)n1cnc2c(cnnc12)-c1ccc(F)c(c1)-c1ccc(cc1F)S(=O)(=O)C(C)C Show InChI InChI=1S/C23H22F2N4O2S/c1-13(2)29-12-26-22-19(11-27-28-23(22)29)15-5-8-20(24)18(9-15)17-7-6-16(10-21(17)25)32(30,31)14(3)4/h5-14H,1-4H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	87.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144243 (US8952008, 42) Show SMILES COc1cc(ccc1-c1cc(ccc1F)-c1cnnc2n(cnc12)C1CCCC1)S(N)(=O)=O Show InChI InChI=1S/C23H22FN5O3S/c1-32-21-11-16(33(25,30)31)7-8-17(21)18-10-14(6-9-20(18)24)19-12-27-28-23-22(19)26-13-29(23)15-4-2-3-5-15/h6-13,15H,2-5H2,1H3,(H2,25,30,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	91.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144249 (US8952008, 48) Show SMILES CCn1cnc2c(cnnc12)-c1ccc(O)c(c1)-c1ccc(cc1OC)S(=O)(=O)CC Show InChI InChI=1S/C22H22N4O4S/c1-4-26-13-23-21-18(12-24-25-22(21)26)14-6-9-19(27)17(10-14)16-8-7-15(11-20(16)30-3)31(28,29)5-2/h6-13,27H,4-5H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	92.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144236 (US8952008, 29) Show SMILES COc1cc(ccc1-c1cc(ccc1F)-c1cnnc2n(cnc12)C1CCC1)S(C)(=O)=O Show InChI InChI=1S/C23H21FN4O3S/c1-31-21-11-16(32(2,29)30)7-8-17(21)18-10-14(6-9-20(18)24)19-12-26-27-23-22(19)25-13-28(23)15-4-3-5-15/h6-13,15H,3-5H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	101	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144261 (US8952008, 17) Show SMILES CCn1cnc2c(cnnc12)-c1cccc(c1)-c1ccc2c(CCS2(=O)=O)c1 Show InChI InChI=1S/C21H18N4O2S/c1-2-25-13-22-20-18(12-23-24-21(20)25)16-5-3-4-14(10-16)15-6-7-19-17(11-15)8-9-28(19,26)27/h3-7,10-13H,2,8-9H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	102	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144228 (US8952008, 5) Show SMILES CCn1cnc2c(cnnc12)-c1ccc(F)c(c1)-c1ccc(cc1C#N)S(=O)(=O)C(C)C Show InChI InChI=1S/C23H20FN5O2S/c1-4-29-13-26-22-20(12-27-28-23(22)29)15-5-8-21(24)19(10-15)18-7-6-17(9-16(18)11-25)32(30,31)14(2)3/h5-10,12-14H,4H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	108	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144244 (US8952008, 43) Show SMILES CCS(=O)(=O)c1ccc(c(OC)c1)-c1cc(ccc1F)-c1cnnc2n(cnc12)C1CCCC1 Show InChI InChI=1S/C25H25FN4O3S/c1-3-34(31,32)18-9-10-19(23(13-18)33-2)20-12-16(8-11-22(20)26)21-14-28-29-25-24(21)27-15-30(25)17-6-4-5-7-17/h8-15,17H,3-7H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	118	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144237 (US8952008, 30) Show SMILES CCCn1cnc2c(cnnc12)-c1ccc(F)c(c1)-c1ccc(cc1)S(=O)(=O)CC Show InChI InChI=1S/C22H21FN4O2S/c1-3-11-27-14-24-21-19(13-25-26-22(21)27)16-7-10-20(23)18(12-16)15-5-8-17(9-6-15)30(28,29)4-2/h5-10,12-14H,3-4,11H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144233 (US8952008, 26) Show SMILES CCS(=O)(=O)c1ccc(c(F)c1)-c1cc(ccc1F)-c1cnnc2n(cnc12)C1CCC1 Show InChI InChI=1S/C23H20F2N4O2S/c1-2-32(30,31)16-7-8-17(21(25)11-16)18-10-14(6-9-20(18)24)19-12-27-28-23-22(19)26-13-29(23)15-4-3-5-15/h6-13,15H,2-5H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	147	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144267 (US8952008, 25) Show SMILES CCS(=O)(=O)c1ccc(c(c1)C#N)-c1cc(ccc1F)-c1cnnc2n(cnc12)C1CC1 Show InChI InChI=1S/C23H18FN5O2S/c1-2-32(30,31)17-6-7-18(15(9-17)11-25)19-10-14(3-8-21(19)24)20-12-27-28-23-22(20)26-13-29(23)16-4-5-16/h3,6-10,12-13,16H,2,4-5H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144231 (US8952008, 18) Show SMILES CC(C)S(=O)(=O)c1ccc(c(c1)C#N)-c1cc(ccc1F)-c1cnnc2n(cnc12)C1CC1 Show InChI InChI=1S/C24H20FN5O2S/c1-14(2)33(31,32)18-6-7-19(16(9-18)11-26)20-10-15(3-8-22(20)25)21-12-28-29-24-23(21)27-13-30(24)17-4-5-17/h3,6-10,12-14,17H,4-5H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	296	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144245 (US8952008, 44) Show SMILES CCn1cnc2c(cnnc12)-c1ccc(CO)c(c1)-c1ccc(cc1F)S(=O)(=O)CC Show InChI InChI=1S/C22H21FN4O3S/c1-3-27-13-24-21-19(11-25-26-22(21)27)14-5-6-15(12-28)18(9-14)17-8-7-16(10-20(17)23)31(29,30)4-2/h5-11,13,28H,3-4,12H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	678	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144247 (US8952008, 46) Show SMILES CCn1cnc2c(cnnc12)-c1ccc(CO)c(c1)-c1ccc(cc1OC)S(=O)(=O)CC Show InChI InChI=1S/C23H24N4O4S/c1-4-27-14-24-22-20(12-25-26-23(22)27)15-6-7-16(13-28)19(10-15)18-9-8-17(11-21(18)31-3)32(29,30)5-2/h6-12,14,28H,4-5,13H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.75E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair