Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Androgen receptor (Rattus norvegicus (Rat)) | BDBM18665 ((2S)-3-(4-acetamidophenoxy)-2-hydroxy-2-methyl-N-[...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | 3.98 | -44.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Tennessee at Memphis | Assay Description The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (... | J Med Chem 47: 993-8 (2004) Article DOI: 10.1021/jm030336u BindingDB Entry DOI: 10.7270/Q2JH3JFB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Androgen receptor (Rattus norvegicus (Rat)) | BDBM18675 ((2S)-2-hydroxy-3-(4-isothiocyanatophenoxy)-2-methy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 4.62 | -44.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Tennessee at Memphis | Assay Description The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (... | J Med Chem 47: 993-8 (2004) Article DOI: 10.1021/jm030336u BindingDB Entry DOI: 10.7270/Q2JH3JFB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Rattus norvegicus (Rat)) | BDBM18661 ((2R)-3-[(4-acetamidophenyl)sulfanyl]-2-hydroxy-2-m...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 4.90 | -44.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Tennessee at Memphis | Assay Description The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (... | J Med Chem 47: 993-8 (2004) Article DOI: 10.1021/jm030336u BindingDB Entry DOI: 10.7270/Q2JH3JFB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Rattus norvegicus (Rat)) | BDBM18667 ((2S)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 6.07 | -43.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Tennessee at Memphis | Assay Description The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (... | J Med Chem 47: 993-8 (2004) Article DOI: 10.1021/jm030336u BindingDB Entry DOI: 10.7270/Q2JH3JFB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Rattus norvegicus (Rat)) | BDBM18663 ((2S)-3-(4-fluorophenoxy)-2-hydroxy-2-methyl-N-[4-n...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | 6.11 | -43.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Tennessee at Memphis | Assay Description The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (... | J Med Chem 47: 993-8 (2004) Article DOI: 10.1021/jm030336u BindingDB Entry DOI: 10.7270/Q2JH3JFB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Androgen receptor (Rattus norvegicus (Rat)) | BDBM18676 ((2S)-3-[(4-fluorophenyl)amino]-2-hydroxy-2-methyl-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 7.96 | -43.0 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Tennessee at Memphis | Assay Description The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (... | J Med Chem 47: 993-8 (2004) Article DOI: 10.1021/jm030336u BindingDB Entry DOI: 10.7270/Q2JH3JFB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Rattus norvegicus (Rat)) | BDBM18668 ((2S)-3-(4-chlorophenoxy)-2-hydroxy-2-methyl-N-[4-n...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | 9.56 | -42.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Tennessee at Memphis | Assay Description The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (... | J Med Chem 47: 993-8 (2004) Article DOI: 10.1021/jm030336u BindingDB Entry DOI: 10.7270/Q2JH3JFB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Rattus norvegicus (Rat)) | BDBM18669 ((2S)-3-(4-bromophenoxy)-2-hydroxy-2-methyl-N-[4-ni...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 11.6 | -42.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Tennessee at Memphis | Assay Description The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (... | J Med Chem 47: 993-8 (2004) Article DOI: 10.1021/jm030336u BindingDB Entry DOI: 10.7270/Q2JH3JFB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Rattus norvegicus (Rat)) | BDBM18672 ((2S)-2-hydroxy-3-(4-methoxyphenoxy)-2-methyl-N-[4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 13.7 | -41.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Tennessee at Memphis | Assay Description The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (... | J Med Chem 47: 993-8 (2004) Article DOI: 10.1021/jm030336u BindingDB Entry DOI: 10.7270/Q2JH3JFB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Rattus norvegicus (Rat)) | BDBM18674 ((2S)-2-hydroxy-3-[4-(1H-indol-5-yl)phenoxy]-2-meth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 17.0 | -41.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Tennessee at Memphis | Assay Description The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (... | J Med Chem 47: 993-8 (2004) Article DOI: 10.1021/jm030336u BindingDB Entry DOI: 10.7270/Q2JH3JFB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Rattus norvegicus (Rat)) | BDBM18670 ((2S)-2-hydroxy-3-(4-iodophenoxy)-2-methyl-N-[4-nit...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 30.0 | -39.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Tennessee at Memphis | Assay Description The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (... | J Med Chem 47: 993-8 (2004) Article DOI: 10.1021/jm030336u BindingDB Entry DOI: 10.7270/Q2JH3JFB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Rattus norvegicus (Rat)) | BDBM18671 ((2S)-2-hydroxy-2-methyl-3-(4-methylphenoxy)-N-[4-n...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 34.8 | -39.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Tennessee at Memphis | Assay Description The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (... | J Med Chem 47: 993-8 (2004) Article DOI: 10.1021/jm030336u BindingDB Entry DOI: 10.7270/Q2JH3JFB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Rattus norvegicus (Rat)) | BDBM18666 ((2S)-3-(4-acetylphenoxy)-2-hydroxy-2-methyl-N-[4-n...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 36.6 | -39.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Tennessee at Memphis | Assay Description The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (... | J Med Chem 47: 993-8 (2004) Article DOI: 10.1021/jm030336u BindingDB Entry DOI: 10.7270/Q2JH3JFB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Rattus norvegicus (Rat)) | BDBM18677 ((2S)-3-[(4-acetamidophenyl)amino]-2-hydroxy-2-meth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 128 | -36.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Tennessee at Memphis | Assay Description The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (... | J Med Chem 47: 993-8 (2004) Article DOI: 10.1021/jm030336u BindingDB Entry DOI: 10.7270/Q2JH3JFB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Rattus norvegicus (Rat)) | BDBM18664 ((2R)-3-(4-fluorophenoxy)-2-hydroxy-2-methyl-N-[4-n...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 225 | -35.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Tennessee at Memphis | Assay Description The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (... | J Med Chem 47: 993-8 (2004) Article DOI: 10.1021/jm030336u BindingDB Entry DOI: 10.7270/Q2JH3JFB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Rattus norvegicus (Rat)) | BDBM18673 (Nonsteroidal AR Ligand, S-14 | tert-butyl N-{4-[(2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 336 | -34.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
University of Tennessee at Memphis | Assay Description The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (... | J Med Chem 47: 993-8 (2004) Article DOI: 10.1021/jm030336u BindingDB Entry DOI: 10.7270/Q2JH3JFB | |||||||||||
More data for this Ligand-Target Pair |