Compile Data Set for Download or QSAR

Found 118 hits Enz. Inhib. hit(s) with all data for entry = 7650   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208443 (US9266869, 1) Show SMILES Cc1ccoc1C(=O)Nc1cccc(c1)C#Cc1cc(cnc1N)C(=O)N=S(C)(C)=O Show InChI InChI=1S/C22H20N4O4S/c1-14-9-10-30-19(14)22(28)25-18-6-4-5-15(11-18)7-8-16-12-17(13-24-20(16)23)21(27)26-31(2,3)29/h4-6,9-13H,1-3H3,(H2,23,24)(H,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	37
Allergan, Inc. US Patent					Assay Description Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of VEGF induced increases in intracellular calcium...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208465 (US9266869, 23) Show SMILES COC(=O)CCCCS(C)(=O)=NC(=O)c1cnc(N)c(c1)C#Cc1cccc(NC(=O)c2occc2C)c1 Show InChI InChI=1S/C27H28N4O6S/c1-18-12-13-37-24(18)27(34)30-22-8-6-7-19(15-22)10-11-20-16-21(17-29-25(20)28)26(33)31-38(3,35)14-5-4-9-23(32)36-2/h6-8,12-13,15-17H,4-5,9,14H2,1-3H3,(H2,28,29)(H,30,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	37
Allergan, Inc. US Patent					Assay Description Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of VEGF induced increases in intracellular calcium...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208468 (US9266869, 26) Show SMILES COC(=O)CCCCS(C)(=O)=NC(=O)c1cnc(N)c(c1)C#Cc1cccc(NC(=O)c2cccc(C)c2)c1 Show InChI InChI=1S/C29H30N4O5S/c1-20-8-6-10-23(16-20)28(35)32-25-11-7-9-21(17-25)13-14-22-18-24(19-31-27(22)30)29(36)33-39(3,37)15-5-4-12-26(34)38-2/h6-11,16-19H,4-5,12,15H2,1-3H3,(H2,30,31)(H,32,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	37
Allergan, Inc. US Patent					Assay Description Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of VEGF induced increases in intracellular calcium...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208469 (US9266869, 27) Show SMILES COC(=O)CCCCS(C)(=O)=NC(=O)c1cnc(N)c(c1)C#Cc1cccc(NC(=O)c2cc(ccc2F)C(F)(F)F)c1 Show InChI InChI=1S/C29H26F4N4O5S/c1-42-25(38)8-3-4-13-43(2,41)37-27(39)20-15-19(26(34)35-17-20)10-9-18-6-5-7-22(14-18)36-28(40)23-16-21(29(31,32)33)11-12-24(23)30/h5-7,11-12,14-17H,3-4,8,13H2,1-2H3,(H2,34,35)(H,36,40)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	37
Allergan, Inc. US Patent					Assay Description Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of VEGF induced increases in intracellular calcium...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208472 (US9266869, 30) Show SMILES COC(=O)CCCCS(C)(=O)=NC(=O)c1cnc(N)c(c1)C#Cc1cccc(NC(=O)c2cccc(OC)c2)c1 Show InChI InChI=1S/C29H30N4O6S/c1-38-25-11-7-9-22(18-25)28(35)32-24-10-6-8-20(16-24)13-14-21-17-23(19-31-27(21)30)29(36)33-40(3,37)15-5-4-12-26(34)39-2/h6-11,16-19H,4-5,12,15H2,1-3H3,(H2,30,31)(H,32,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	37
Allergan, Inc. US Patent					Assay Description Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of VEGF induced increases in intracellular calcium...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208478 (US9266869, 36) Show SMILES COC(=O)CCCCS(C)(=O)=NC(=O)c1cnc(N)c(c1)C#Cc1cccc(c1)C(=O)Nc1cc(on1)C(C)(C)C Show InChI InChI=1S/C29H33N5O6S/c1-29(2,3)23-17-24(33-40-23)32-27(36)21-10-8-9-19(15-21)12-13-20-16-22(18-31-26(20)30)28(37)34-41(5,38)14-7-6-11-25(35)39-4/h8-10,15-18H,6-7,11,14H2,1-5H3,(H2,30,31)(H,32,33,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	37
Allergan, Inc. US Patent					Assay Description Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of VEGF induced increases in intracellular calcium...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208475 (US9266869, 33) Show SMILES COC(=O)CCCC[S@@](C)(=O)=NC(=O)c1cnc(N)c(c1)C#Cc1cccc(NC(=O)c2occc2C)c1 |r| Show InChI InChI=1S/C27H28N4O6S/c1-18-12-13-37-24(18)27(34)30-22-8-6-7-19(15-22)10-11-20-16-21(17-29-25(20)28)26(33)31-38(3,35)14-5-4-9-23(32)36-2/h6-8,12-13,15-17H,4-5,9,14H2,1-3H3,(H2,28,29)(H,30,34)/t38-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	37
Allergan, Inc. US Patent					Assay Description Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of VEGF induced increases in intracellular calcium...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208474 (US9266869, 32) Show SMILES COC(=O)CCCC[S@](C)(=O)=NC(=O)c1cnc(N)c(c1)C#Cc1cccc(NC(=O)c2occc2C)c1 |r| Show InChI InChI=1S/C27H28N4O6S/c1-18-12-13-37-24(18)27(34)30-22-8-6-7-19(15-22)10-11-20-16-21(17-29-25(20)28)26(33)31-38(3,35)14-5-4-9-23(32)36-2/h6-8,12-13,15-17H,4-5,9,14H2,1-3H3,(H2,28,29)(H,30,34)/t38-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	37
Allergan, Inc. US Patent					Assay Description Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of VEGF induced increases in intracellular calcium...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208481 (US9266869, 39) Show SMILES Cc1ccoc1C(=O)Nc1cccc(c1)C#Cc1cncc(c1)C(=O)N=S(C)(=O)CCCO Show InChI InChI=1S/C24H23N3O5S/c1-17-9-11-32-22(17)24(30)26-21-6-3-5-18(14-21)7-8-19-13-20(16-25-15-19)23(29)27-33(2,31)12-4-10-28/h3,5-6,9,11,13-16,28H,4,10,12H2,1-2H3,(H,26,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	37
Allergan, Inc. US Patent					Assay Description Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of VEGF induced increases in intracellular calcium...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208447 (US9266869, 5) Show SMILES CS(C)(=O)=NC(=O)c1cnc(N)c(c1)C#Cc1cccc(NC(=O)c2ccc(Cl)cc2)c1 Show InChI InChI=1S/C23H19ClN4O3S/c1-32(2,31)28-23(30)18-13-17(21(25)26-14-18)7-6-15-4-3-5-20(12-15)27-22(29)16-8-10-19(24)11-9-16/h3-5,8-14H,1-2H3,(H2,25,26)(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208446 (US9266869, 4) Show SMILES Cc1ccoc1C(=O)Nc1cccc(c1)C#Cc1cc(cnc1N)C(=O)N=S1(=O)CCCC1 Show InChI InChI=1S/C24H22N4O4S/c1-16-9-10-32-21(16)24(30)27-20-6-4-5-17(13-20)7-8-18-14-19(15-26-22(18)25)23(29)28-33(31)11-2-3-12-33/h4-6,9-10,13-15H,2-3,11-12H2,1H3,(H2,25,26)(H,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208482 (US9266869, 40) Show SMILES Cc1ccoc1C(=O)Nc1cccc(c1)C#Cc1cc(cnc1N)C(=O)N=S(C)(=O)CCCO Show InChI InChI=1S/C24H24N4O5S/c1-16-9-11-33-21(16)24(31)27-20-6-3-5-17(13-20)7-8-18-14-19(15-26-22(18)25)23(30)28-34(2,32)12-4-10-29/h3,5-6,9,11,13-15,29H,4,10,12H2,1-2H3,(H2,25,26)(H,27,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	37
Allergan, Inc. US Patent					Assay Description Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of VEGF induced increases in intracellular calcium...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208444 (US9266869, 2) Show SMILES Cc1ccoc1C(=O)Nc1cccc(c1)C#Cc1cncc(c1)C(=O)N=S(C)(C)=O Show InChI InChI=1S/C22H19N3O4S/c1-15-9-10-29-20(15)22(27)24-19-6-4-5-16(12-19)7-8-17-11-18(14-23-13-17)21(26)25-30(2,3)28/h4-6,9-14H,1-3H3,(H,24,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208445 (US9266869, 3) Show SMILES Cc1ccoc1C(=O)Nc1cccc(c1)C#Cc1cncc(c1)C(=O)N=S1(=O)CCCC1 Show InChI InChI=1S/C24H21N3O4S/c1-17-9-10-31-22(17)24(29)26-21-6-4-5-18(14-21)7-8-19-13-20(16-25-15-19)23(28)27-32(30)11-2-3-12-32/h4-6,9-10,13-16H,2-3,11-12H2,1H3,(H,26,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208476 (US9266869, 34) Show SMILES COC(=O)CCCCS(C)(=O)=NC(=O)c1cnc(N)c(c1)C#Cc1cccc(c1)C(=O)Nc1cccc(C)c1 Show InChI InChI=1S/C29H30N4O5S/c1-20-8-6-11-25(16-20)32-28(35)23-10-7-9-21(17-23)13-14-22-18-24(19-31-27(22)30)29(36)33-39(3,37)15-5-4-12-26(34)38-2/h6-11,16-19H,4-5,12,15H2,1-3H3,(H2,30,31)(H,32,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	37
Allergan, Inc. US Patent					Assay Description Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of VEGF induced increases in intracellular calcium...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208446 (US9266869, 4) Show SMILES Cc1ccoc1C(=O)Nc1cccc(c1)C#Cc1cc(cnc1N)C(=O)N=S1(=O)CCCC1 Show InChI InChI=1S/C24H22N4O4S/c1-16-9-10-32-21(16)24(30)27-20-6-4-5-17(13-20)7-8-18-14-19(15-26-22(18)25)23(29)28-33(31)11-2-3-12-33/h4-6,9-10,13-15H,2-3,11-12H2,1H3,(H2,25,26)(H,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	37
Allergan, Inc. US Patent					Assay Description Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of VEGF induced increases in intracellular calcium...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208459 (US9266869, 17) Show SMILES Cc1cccc(c1)C(=O)Nc1cccc(c1)C#Cc1cncc(c1)C(=O)N=S(=O)(CCCO)CCCO Show InChI InChI=1S/C28H29N3O5S/c1-21-6-2-8-24(16-21)27(34)30-26-9-3-7-22(18-26)10-11-23-17-25(20-29-19-23)28(35)31-37(36,14-4-12-32)15-5-13-33/h2-3,6-9,16-20,32-33H,4-5,12-15H2,1H3,(H,30,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208450 (US9266869, 8) Show SMILES Cc1ccc(F)c(NC(=O)Nc2cccc(c2)C#Cc2cncc(c2)C(=O)N=S(C)(C)=O)c1 Show InChI InChI=1S/C24H21FN4O3S/c1-16-7-10-21(25)22(11-16)28-24(31)27-20-6-4-5-17(13-20)8-9-18-12-19(15-26-14-18)23(30)29-33(2,3)32/h4-7,10-15H,1-3H3,(H2,27,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208457 (US9266869, 15) Show SMILES Cc1ccoc1C(=O)Nc1cccc(c1)C#Cc1cc(cnc1N)C(=O)N=S(=O)(CCCO)CCCO Show InChI InChI=1S/C26H28N4O6S/c1-18-9-12-36-23(18)26(34)29-22-6-2-5-19(15-22)7-8-20-16-21(17-28-24(20)27)25(33)30-37(35,13-3-10-31)14-4-11-32/h2,5-6,9,12,15-17,31-32H,3-4,10-11,13-14H2,1H3,(H2,27,28)(H,29,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208454 (US9266869, 12) Show SMILES Cc1ccoc1C(=O)Nc1cccc(c1)C#Cc1cc(cnc1N)C(=O)N=S(C)(=O)CC(=O)N1CC[C@H](O)C1 |r| Show InChI InChI=1S/C27H27N5O6S/c1-17-9-11-38-24(17)27(36)30-21-5-3-4-18(12-21)6-7-19-13-20(14-29-25(19)28)26(35)31-39(2,37)16-23(34)32-10-8-22(33)15-32/h3-5,9,11-14,22,33H,8,10,15-16H2,1-2H3,(H2,28,29)(H,30,36)/t22-,39?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	37
Allergan, Inc. US Patent					Assay Description Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of VEGF induced increases in intracellular calcium...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208464 (US9266869, 22) Show SMILES Cc1cccc(NC(=O)c2cccc(c2)C#Cc2cc(cnc2N)C(=O)N=S(=O)(CCCO)CCCO)c1 Show InChI InChI=1S/C28H30N4O5S/c1-20-6-2-9-25(16-20)31-27(35)23-8-3-7-21(17-23)10-11-22-18-24(19-30-26(22)29)28(36)32-38(37,14-4-12-33)15-5-13-34/h2-3,6-9,16-19,33-34H,4-5,12-15H2,1H3,(H2,29,30)(H,31,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208445 (US9266869, 3) Show SMILES Cc1ccoc1C(=O)Nc1cccc(c1)C#Cc1cncc(c1)C(=O)N=S1(=O)CCCC1 Show InChI InChI=1S/C24H21N3O4S/c1-17-9-10-31-22(17)24(29)26-21-6-4-5-18(14-21)7-8-19-13-20(16-25-15-19)23(28)27-32(30)11-2-3-12-32/h4-6,9-10,13-16H,2-3,11-12H2,1H3,(H,26,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	37
Allergan, Inc. US Patent					Assay Description Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of VEGF induced increases in intracellular calcium...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208458 (US9266869, 16) Show SMILES OCCCS(=O)(CCCO)=NC(=O)c1cncc(c1)C#Cc1cccc(NC(=O)c2ccc(Cl)c(c2)C(F)(F)F)c1 Show InChI InChI=1S/C28H25ClF3N3O5S/c29-25-9-8-21(16-24(25)28(30,31)32)26(38)34-23-5-1-4-19(15-23)6-7-20-14-22(18-33-17-20)27(39)35-41(40,12-2-10-36)13-3-11-37/h1,4-5,8-9,14-18,36-37H,2-3,10-13H2,(H,34,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208483 (US9266869, 41) Show SMILES Cc1ccoc1C(=O)Nc1cccc(c1)C#Cc1cncc(c1)C(=O)N=[S@@](C)(=O)CCCO |r| Show InChI InChI=1S/C24H23N3O5S/c1-17-9-11-32-22(17)24(30)26-21-6-3-5-18(14-21)7-8-19-13-20(16-25-15-19)23(29)27-33(2,31)12-4-10-28/h3,5-6,9,11,13-16,28H,4,10,12H2,1-2H3,(H,26,30)/t33-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208482 (US9266869, 40) Show SMILES Cc1ccoc1C(=O)Nc1cccc(c1)C#Cc1cc(cnc1N)C(=O)N=S(C)(=O)CCCO Show InChI InChI=1S/C24H24N4O5S/c1-16-9-11-33-21(16)24(31)27-20-6-3-5-17(13-20)7-8-18-14-19(15-26-22(18)25)23(30)28-34(2,32)12-4-10-29/h3,5-6,9,11,13-15,29H,4,10,12H2,1-2H3,(H2,25,26)(H,27,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208474 (US9266869, 32) Show SMILES COC(=O)CCCC[S@](C)(=O)=NC(=O)c1cnc(N)c(c1)C#Cc1cccc(NC(=O)c2occc2C)c1 |r| Show InChI InChI=1S/C27H28N4O6S/c1-18-12-13-37-24(18)27(34)30-22-8-6-7-19(15-22)10-11-20-16-21(17-29-25(20)28)26(33)31-38(3,35)14-5-4-9-23(32)36-2/h6-8,12-13,15-17H,4-5,9,14H2,1-3H3,(H2,28,29)(H,30,34)/t38-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208454 (US9266869, 12) Show SMILES Cc1ccoc1C(=O)Nc1cccc(c1)C#Cc1cc(cnc1N)C(=O)N=S(C)(=O)CC(=O)N1CC[C@H](O)C1 |r| Show InChI InChI=1S/C27H27N5O6S/c1-17-9-11-38-24(17)27(36)30-21-5-3-4-18(12-21)6-7-19-13-20(14-29-25(19)28)26(35)31-39(2,37)16-23(34)32-10-8-22(33)15-32/h3-5,9,11-14,22,33H,8,10,15-16H2,1-2H3,(H2,28,29)(H,30,36)/t22-,39?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208460 (US9266869, 18) Show SMILES OCCCS(=O)(CCCO)=NC(=O)c1cncc(c1)C#Cc1cccc(NC(=O)c2cccc(c2)C(F)(F)F)c1 Show InChI InChI=1S/C28H26F3N3O5S/c29-28(30,31)24-7-2-6-22(17-24)26(37)33-25-8-1-5-20(16-25)9-10-21-15-23(19-32-18-21)27(38)34-40(39,13-3-11-35)14-4-12-36/h1-2,5-8,15-19,35-36H,3-4,11-14H2,(H,33,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208471 (US9266869, 29) Show SMILES COC(=O)CCCCS(C)(=O)=NC(=O)c1cnc(N)c(c1)C#Cc1cccc(NC(=O)c2ccc(Cl)c(c2)C(F)(F)F)c1 Show InChI InChI=1S/C29H26ClF3N4O5S/c1-42-25(38)8-3-4-13-43(2,41)37-28(40)21-15-19(26(34)35-17-21)10-9-18-6-5-7-22(14-18)36-27(39)20-11-12-24(30)23(16-20)29(31,32)33/h5-7,11-12,14-17H,3-4,8,13H2,1-2H3,(H2,34,35)(H,36,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208470 (US9266869, 28) Show SMILES COC(=O)CCCCS(C)(=O)=NC(=O)c1cnc(N)c(c1)C#Cc1cccc(NC(=O)c2cccc(c2)C(F)(F)F)c1 Show InChI InChI=1S/C29H27F3N4O5S/c1-41-25(37)11-3-4-14-42(2,40)36-28(39)22-16-20(26(33)34-18-22)13-12-19-7-5-10-24(15-19)35-27(38)21-8-6-9-23(17-21)29(30,31)32/h5-10,15-18H,3-4,11,14H2,1-2H3,(H2,33,34)(H,35,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208473 (US9266869, 31) Show SMILES COC(=O)CCCCS(C)(=O)=NC(=O)c1cnc(N)c(c1)C#Cc1cccc(NC(=O)c2ccc(OC)c(OC)c2)c1 Show InChI InChI=1S/C30H32N4O7S/c1-39-25-14-13-22(18-26(25)40-2)29(36)33-24-9-7-8-20(16-24)11-12-21-17-23(19-32-28(21)31)30(37)34-42(4,38)15-6-5-10-27(35)41-3/h7-9,13-14,16-19H,5-6,10,15H2,1-4H3,(H2,31,32)(H,33,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	37
Allergan, Inc. US Patent					Assay Description Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of VEGF induced increases in intracellular calcium...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208480 (US9266869, 38) Show SMILES COC(=O)CCCCS(C)(=O)=NC(=O)c1cnc(N)c(c1)C#Cc1cccc(NC(=O)Nc2cccc(C)c2)c1 Show InChI InChI=1S/C29H31N5O5S/c1-20-8-6-10-24(16-20)32-29(37)33-25-11-7-9-21(17-25)13-14-22-18-23(19-31-27(22)30)28(36)34-40(3,38)15-5-4-12-26(35)39-2/h6-11,16-19H,4-5,12,15H2,1-3H3,(H2,30,31)(H2,32,33,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208470 (US9266869, 28) Show SMILES COC(=O)CCCCS(C)(=O)=NC(=O)c1cnc(N)c(c1)C#Cc1cccc(NC(=O)c2cccc(c2)C(F)(F)F)c1 Show InChI InChI=1S/C29H27F3N4O5S/c1-41-25(37)11-3-4-14-42(2,40)36-28(39)22-16-20(26(33)34-18-22)13-12-19-7-5-10-24(15-19)35-27(38)21-8-6-9-23(17-21)29(30,31)32/h5-10,15-18H,3-4,11,14H2,1-2H3,(H2,33,34)(H,35,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	37
Allergan, Inc. US Patent					Assay Description Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of VEGF induced increases in intracellular calcium...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208468 (US9266869, 26) Show SMILES COC(=O)CCCCS(C)(=O)=NC(=O)c1cnc(N)c(c1)C#Cc1cccc(NC(=O)c2cccc(C)c2)c1 Show InChI InChI=1S/C29H30N4O5S/c1-20-8-6-10-23(16-20)28(35)32-25-11-7-9-21(17-25)13-14-22-18-24(19-31-27(22)30)29(36)33-39(3,37)15-5-4-12-26(34)38-2/h6-11,16-19H,4-5,12,15H2,1-3H3,(H2,30,31)(H,32,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208466 (US9266869, 24) Show SMILES Cc1ccoc1C(=O)Nc1cccc(c1)C#Cc1cc(cnc1N)C(=O)N=S(C)(=O)CCCCC(O)=O Show InChI InChI=1S/C26H26N4O6S/c1-17-11-12-36-23(17)26(34)29-21-7-5-6-18(14-21)9-10-19-15-20(16-28-24(19)27)25(33)30-37(2,35)13-4-3-8-22(31)32/h5-7,11-12,14-16H,3-4,8,13H2,1-2H3,(H2,27,28)(H,29,34)(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208456 (US9266869, 14) Show SMILES Cc1ccoc1C(=O)Nc1cccc(c1)C#Cc1cncc(c1)C(=O)N=S(=O)(CCCO)CCCO Show InChI InChI=1S/C26H27N3O6S/c1-19-9-12-35-24(19)26(33)28-23-6-2-5-20(16-23)7-8-21-15-22(18-27-17-21)25(32)29-36(34,13-3-10-30)14-4-11-31/h2,5-6,9,12,15-18,30-31H,3-4,10-11,13-14H2,1H3,(H,28,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208461 (US9266869, 19) Show SMILES OCCCS(=O)(CCCO)=NC(=O)c1cncc(c1)C#Cc1cccc(NC(=O)c2ccc(F)c(Cl)c2)c1 Show InChI InChI=1S/C27H25ClFN3O5S/c28-24-16-21(8-9-25(24)29)26(35)31-23-5-1-4-19(15-23)6-7-20-14-22(18-30-17-20)27(36)32-38(37,12-2-10-33)13-3-11-34/h1,4-5,8-9,14-18,33-34H,2-3,10-13H2,(H,31,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208463 (US9266869, 21) Show SMILES COc1cccc(c1)C(=O)Nc1cccc(c1)C#Cc1cc(cnc1N)C(=O)N=S(=O)(CCCO)CCCO Show InChI InChI=1S/C28H30N4O6S/c1-38-25-9-3-7-22(18-25)27(35)31-24-8-2-6-20(16-24)10-11-21-17-23(19-30-26(21)29)28(36)32-39(37,14-4-12-33)15-5-13-34/h2-3,6-9,16-19,33-34H,4-5,12-15H2,1H3,(H2,29,30)(H,31,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208484 (US9266869, 42) Show SMILES Cc1ccoc1C(=O)Nc1cccc(c1)C#Cc1cncc(c1)C(=O)N=[S@](C)(=O)CCCO |r| Show InChI InChI=1S/C24H23N3O5S/c1-17-9-11-32-22(17)24(30)26-21-6-3-5-18(14-21)7-8-19-13-20(16-25-15-19)23(29)27-33(2,31)12-4-10-28/h3,5-6,9,11,13-16,28H,4,10,12H2,1-2H3,(H,26,30)/t33-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208479 (US9266869, 37) Show SMILES COC(=O)CCCCS(C)(=O)=NC(=O)c1cnc(N)c(c1)C#Cc1cccc(NC(=O)Nc2cc(C)ccc2F)c1 Show InChI InChI=1S/C29H30FN5O5S/c1-19-10-13-24(30)25(15-19)34-29(38)33-23-8-6-7-20(16-23)11-12-21-17-22(18-32-27(21)31)28(37)35-41(3,39)14-5-4-9-26(36)40-2/h6-8,10,13,15-18H,4-5,9,14H2,1-3H3,(H2,31,32)(H2,33,34,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208472 (US9266869, 30) Show SMILES COC(=O)CCCCS(C)(=O)=NC(=O)c1cnc(N)c(c1)C#Cc1cccc(NC(=O)c2cccc(OC)c2)c1 Show InChI InChI=1S/C29H30N4O6S/c1-38-25-11-7-9-22(18-25)28(35)32-24-10-6-8-20(16-24)13-14-21-17-23(19-31-27(21)30)29(36)33-40(3,37)15-5-4-12-26(34)39-2/h6-11,16-19H,4-5,12,15H2,1-3H3,(H2,30,31)(H,32,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208448 (US9266869, 6) Show SMILES Cc1ccc(F)c(c1)C(=O)Nc1cccc(c1)C#Cc1cc(cnc1N)C(=O)N=S(C)(C)=O Show InChI InChI=1S/C24H21FN4O3S/c1-15-7-10-21(25)20(11-15)24(31)28-19-6-4-5-16(12-19)8-9-17-13-18(14-27-22(17)26)23(30)29-33(2,3)32/h4-7,10-14H,1-3H3,(H2,26,27)(H,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	37
Allergan, Inc. US Patent					Assay Description Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of VEGF induced increases in intracellular calcium...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208443 (US9266869, 1) Show SMILES Cc1ccoc1C(=O)Nc1cccc(c1)C#Cc1cc(cnc1N)C(=O)N=S(C)(C)=O Show InChI InChI=1S/C22H20N4O4S/c1-14-9-10-30-19(14)22(28)25-18-6-4-5-15(11-18)7-8-16-12-17(13-24-20(16)23)21(27)26-31(2,3)29/h4-6,9-13H,1-3H3,(H2,23,24)(H,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208449 (US9266869, 7) Show SMILES Cn1ccnc1C(=O)Nc1cccc(c1)C#Cc1cc(cnc1N)C(=O)N=S(C)(C)=O Show InChI InChI=1S/C21H20N6O3S/c1-27-10-9-23-19(27)21(29)25-17-6-4-5-14(11-17)7-8-15-12-16(13-24-18(15)22)20(28)26-31(2,3)30/h4-6,9-13H,1-3H3,(H2,22,24)(H,25,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208453 (US9266869, 11) Show SMILES Cc1ccc(NC(=O)Nc2cccc(c2)C#Cc2cncc(c2)C(=O)N=S(C)(C)=O)cc1 Show InChI InChI=1S/C24H22N4O3S/c1-17-7-11-21(12-8-17)26-24(30)27-22-6-4-5-18(14-22)9-10-19-13-20(16-25-15-19)23(29)28-32(2,3)31/h4-8,11-16H,1-3H3,(H2,26,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208475 (US9266869, 33) Show SMILES COC(=O)CCCC[S@@](C)(=O)=NC(=O)c1cnc(N)c(c1)C#Cc1cccc(NC(=O)c2occc2C)c1 |r| Show InChI InChI=1S/C27H28N4O6S/c1-18-12-13-37-24(18)27(34)30-22-8-6-7-19(15-22)10-11-20-16-21(17-29-25(20)28)26(33)31-38(3,35)14-5-4-9-23(32)36-2/h6-8,12-13,15-17H,4-5,9,14H2,1-3H3,(H2,28,29)(H,30,34)/t38-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208444 (US9266869, 2) Show SMILES Cc1ccoc1C(=O)Nc1cccc(c1)C#Cc1cncc(c1)C(=O)N=S(C)(C)=O Show InChI InChI=1S/C22H19N3O4S/c1-15-9-10-29-20(15)22(27)24-19-6-4-5-16(12-19)7-8-17-11-18(14-23-13-17)21(26)25-30(2,3)28/h4-6,9-14H,1-3H3,(H,24,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	37
Allergan, Inc. US Patent					Assay Description Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of VEGF induced increases in intracellular calcium...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM208471 (US9266869, 29) Show SMILES COC(=O)CCCCS(C)(=O)=NC(=O)c1cnc(N)c(c1)C#Cc1cccc(NC(=O)c2ccc(Cl)c(c2)C(F)(F)F)c1 Show InChI InChI=1S/C29H26ClF3N4O5S/c1-42-25(38)8-3-4-13-43(2,41)37-28(40)21-15-19(26(34)35-17-21)10-9-18-6-5-7-22(14-18)36-27(39)20-11-12-24(30)23(16-20)29(31,32)33/h5-7,11-12,14-17H,3-4,8,13H2,1-2H3,(H2,34,35)(H,36,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	37
Allergan, Inc. US Patent					Assay Description Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of VEGF induced increases in intracellular calcium...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM208444 (US9266869, 2) Show SMILES Cc1ccoc1C(=O)Nc1cccc(c1)C#Cc1cncc(c1)C(=O)N=S(C)(C)=O Show InChI InChI=1S/C22H19N3O4S/c1-15-9-10-29-20(15)22(27)24-19-6-4-5-16(12-19)7-8-17-11-18(14-23-13-17)21(26)25-30(2,3)28/h4-6,9-14H,1-3H3,(H,24,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical PDGFRbeta kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug of poly-Glu-Tyr (4:1) in 10 mM ...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM208459 (US9266869, 17) Show SMILES Cc1cccc(c1)C(=O)Nc1cccc(c1)C#Cc1cncc(c1)C(=O)N=S(=O)(CCCO)CCCO Show InChI InChI=1S/C28H29N3O5S/c1-21-6-2-8-24(16-21)27(34)30-26-9-3-7-22(18-26)10-11-23-17-25(20-29-19-23)28(35)31-37(36,14-4-12-32)15-5-13-33/h2-3,6-9,16-20,32-33H,4-5,12-15H2,1H3,(H,30,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical PDGFRbeta kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug of poly-Glu-Tyr (4:1) in 10 mM ...				US Patent US9266869 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H33
					More data for this Ligand-Target Pair

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