Found 36 hits Enz. Inhib. hit(s) with all data for entry = 50009664 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50086359
(CHEMBL147191 | N-Cyclohexylmethyl-2,2-dimethyl-3-m...)Show InChI InChI=1S/C19H30N2O/c1-19(2,17(20-3)16-12-8-5-9-13-16)18(22)21-14-15-10-6-4-7-11-15/h5,8-9,12-13,15,17,20H,4,6-7,10-11,14H2,1-3H3,(H,21,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]U-69,593 binding to human Opioid receptor kappa 1 expressed in HEK 293 cells |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50000788
((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)Show SMILES Oc1ccc2C[C@H]3N(CC=C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O |r| Show InChI InChI=1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| DrugBank
PubMed
| 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]U-69,593 binding to human Opioid receptor kappa 1 expressed in HEK 293 cells |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50086361
(3-(3-Hydroxy-phenyl)-2,2-dimethyl-3-methylamino-N-...)Show SMILES CNC(c1cccc(O)c1)C(C)(C)C(=O)NCc1cccc2ccccc12 Show InChI InChI=1S/C23H26N2O2/c1-23(2,21(24-3)17-10-7-12-19(26)14-17)22(27)25-15-18-11-6-9-16-8-4-5-13-20(16)18/h4-14,21,24,26H,15H2,1-3H3,(H,25,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]U-69,593 binding to human Opioid receptor kappa 1 expressed in HEK 293 cells |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50086367
(3-(3-Hydroxy-phenyl)-2,2-dimethyl-3-methylamino-N-...)Show InChI InChI=1S/C20H26N2O2/c1-20(2,18(21-3)16-10-7-11-17(23)14-16)19(24)22-13-12-15-8-5-4-6-9-15/h4-11,14,18,21,23H,12-13H2,1-3H3,(H,22,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-DAMGO binding to rat Opioid receptor mu 1 |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50086361
(3-(3-Hydroxy-phenyl)-2,2-dimethyl-3-methylamino-N-...)Show SMILES CNC(c1cccc(O)c1)C(C)(C)C(=O)NCc1cccc2ccccc12 Show InChI InChI=1S/C23H26N2O2/c1-23(2,21(24-3)17-10-7-12-19(26)14-17)22(27)25-15-18-11-6-9-16-8-4-5-13-20(16)18/h4-14,21,24,26H,15H2,1-3H3,(H,25,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-DAMGO binding to rat Opioid receptor mu 1 |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50000788
((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)Show SMILES Oc1ccc2C[C@H]3N(CC=C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O |r| Show InChI InChI=1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-DAMGO binding to rat Opioid receptor mu 1 |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50086363
(3-(Cyclopropylmethyl-methyl-amino)-3-(3-hydroxy-ph...)Show SMILES CN(CC1CC1)C(c1cccc(O)c1)C(C)(C)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C24H32N2O2/c1-24(2,23(28)25-15-14-18-8-5-4-6-9-18)22(26(3)17-19-12-13-19)20-10-7-11-21(27)16-20/h4-11,16,19,22,27H,12-15,17H2,1-3H3,(H,25,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]U-69,593 binding to human Opioid receptor kappa 1 expressed in HEK 293 cells |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50086366
(3-(3-Hydroxy-phenyl)-2,2-dimethyl-3-methylamino-N-...)Show InChI InChI=1S/C21H28N2O2/c1-21(2,19(22-3)17-12-7-13-18(24)15-17)20(25)23-14-8-11-16-9-5-4-6-10-16/h4-7,9-10,12-13,15,19,22,24H,8,11,14H2,1-3H3,(H,23,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]U-69,593 binding to human Opioid receptor kappa 1 expressed in HEK 293 cells |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50086360
(CHEMBL347531 | N-Cyclohexylmethyl-3-(3-hydroxy-phe...)Show InChI InChI=1S/C19H30N2O2/c1-19(2,17(20-3)15-10-7-11-16(22)12-15)18(23)21-13-14-8-5-4-6-9-14/h7,10-12,14,17,20,22H,4-6,8-9,13H2,1-3H3,(H,21,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 4.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-DAMGO binding to rat Opioid receptor mu 1 |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50086364
(CHEMBL146750 | N-Benzyl-3-(3-hydroxy-phenyl)-2,2-d...)Show InChI InChI=1S/C19H24N2O2/c1-19(2,17(20-3)15-10-7-11-16(22)12-15)18(23)21-13-14-8-5-4-6-9-14/h4-12,17,20,22H,13H2,1-3H3,(H,21,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]U-69,593 binding to human Opioid receptor kappa 1 expressed in HEK 293 cells |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50086360
(CHEMBL347531 | N-Cyclohexylmethyl-3-(3-hydroxy-phe...)Show InChI InChI=1S/C19H30N2O2/c1-19(2,17(20-3)15-10-7-11-16(22)12-15)18(23)21-13-14-8-5-4-6-9-14/h7,10-12,14,17,20,22H,4-6,8-9,13H2,1-3H3,(H,21,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 5.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]U-69,593 binding to human Opioid receptor kappa 1 expressed in HEK 293 cells |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50086367
(3-(3-Hydroxy-phenyl)-2,2-dimethyl-3-methylamino-N-...)Show InChI InChI=1S/C20H26N2O2/c1-20(2,18(21-3)16-10-7-11-17(23)14-16)19(24)22-13-12-15-8-5-4-6-9-15/h4-11,14,18,21,23H,12-13H2,1-3H3,(H,22,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 6.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]U-69,593 binding to human Opioid receptor kappa 1 expressed in HEK 293 cells |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50086364
(CHEMBL146750 | N-Benzyl-3-(3-hydroxy-phenyl)-2,2-d...)Show InChI InChI=1S/C19H24N2O2/c1-19(2,17(20-3)15-10-7-11-16(22)12-15)18(23)21-13-14-8-5-4-6-9-14/h4-12,17,20,22H,13H2,1-3H3,(H,21,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 8.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-DAMGO binding to rat Opioid receptor mu 1 |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50086366
(3-(3-Hydroxy-phenyl)-2,2-dimethyl-3-methylamino-N-...)Show InChI InChI=1S/C21H28N2O2/c1-21(2,19(22-3)17-12-7-13-18(24)15-17)20(25)23-14-8-11-16-9-5-4-6-10-16/h4-7,9-10,12-13,15,19,22,24H,8,11,14H2,1-3H3,(H,23,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-DAMGO binding to rat Opioid receptor mu 1 |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50086357
(2,2-Dimethyl-3-methylamino-N-phenethyl-3-phenyl-pr...)Show InChI InChI=1S/C20H26N2O/c1-20(2,18(21-3)17-12-8-5-9-13-17)19(23)22-15-14-16-10-6-4-7-11-16/h4-13,18,21H,14-15H2,1-3H3,(H,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-DAMGO binding to rat Opioid receptor mu 1 |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50086365
(3-(Butyl-methyl-amino)-3-(3-hydroxy-phenyl)-2,2-di...)Show SMILES CCCCN(C)C(c1cccc(O)c1)C(C)(C)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C24H34N2O2/c1-5-6-17-26(4)22(20-13-10-14-21(27)18-20)24(2,3)23(28)25-16-15-19-11-8-7-9-12-19/h7-14,18,22,27H,5-6,15-17H2,1-4H3,(H,25,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-DAMGO binding to rat Opioid receptor mu 1 |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50086363
(3-(Cyclopropylmethyl-methyl-amino)-3-(3-hydroxy-ph...)Show SMILES CN(CC1CC1)C(c1cccc(O)c1)C(C)(C)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C24H32N2O2/c1-24(2,23(28)25-15-14-18-8-5-4-6-9-18)22(26(3)17-19-12-13-19)20-10-7-11-21(27)16-20/h4-11,16,19,22,27H,12-15,17H2,1-3H3,(H,25,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-DAMGO binding to rat Opioid receptor mu 1 |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50000788
((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)Show SMILES Oc1ccc2C[C@H]3N(CC=C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O |r| Show InChI InChI=1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| DrugBank
PubMed
| 41 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-naltrindole binding to human Opioid receptor delta 1 in CHO cells |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50086357
(2,2-Dimethyl-3-methylamino-N-phenethyl-3-phenyl-pr...)Show InChI InChI=1S/C20H26N2O/c1-20(2,18(21-3)17-12-8-5-9-13-17)19(23)22-15-14-16-10-6-4-7-11-16/h4-13,18,21H,14-15H2,1-3H3,(H,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 49 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]U-69,593 binding to human Opioid receptor kappa 1 expressed in HEK 293 cells |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50086365
(3-(Butyl-methyl-amino)-3-(3-hydroxy-phenyl)-2,2-di...)Show SMILES CCCCN(C)C(c1cccc(O)c1)C(C)(C)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C24H34N2O2/c1-5-6-17-26(4)22(20-13-10-14-21(27)18-20)24(2,3)23(28)25-16-15-19-11-8-7-9-12-19/h7-14,18,22,27H,5-6,15-17H2,1-4H3,(H,25,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 75 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]U-69,593 binding to human Opioid receptor kappa 1 expressed in HEK 293 cells |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50086358
(CHEMBL347316 | N-Cyclopropylmethyl-3-(3-hydroxy-ph...)Show InChI InChI=1S/C16H24N2O2/c1-16(2,15(20)18-10-11-7-8-11)14(17-3)12-5-4-6-13(19)9-12/h4-6,9,11,14,17,19H,7-8,10H2,1-3H3,(H,18,20) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 75 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]U-69,593 binding to human Opioid receptor kappa 1 expressed in HEK 293 cells |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50086359
(CHEMBL147191 | N-Cyclohexylmethyl-2,2-dimethyl-3-m...)Show InChI InChI=1S/C19H30N2O/c1-19(2,17(20-3)16-12-8-5-9-13-16)18(22)21-14-15-10-6-4-7-11-15/h5,8-9,12-13,15,17,20H,4,6-7,10-11,14H2,1-3H3,(H,21,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 85 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-DAMGO binding to rat Opioid receptor mu 1 |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50086362
(CHEMBL149143 | N-Benzyl-2,2-dimethyl-3-methylamino...)Show InChI InChI=1S/C19H24N2O/c1-19(2,17(20-3)16-12-8-5-9-13-16)18(22)21-14-15-10-6-4-7-11-15/h4-13,17,20H,14H2,1-3H3,(H,21,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 95 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-DAMGO binding to rat Opioid receptor mu 1 |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50086361
(3-(3-Hydroxy-phenyl)-2,2-dimethyl-3-methylamino-N-...)Show SMILES CNC(c1cccc(O)c1)C(C)(C)C(=O)NCc1cccc2ccccc12 Show InChI InChI=1S/C23H26N2O2/c1-23(2,21(24-3)17-10-7-12-19(26)14-17)22(27)25-15-18-11-6-9-16-8-4-5-13-20(16)18/h4-14,21,24,26H,15H2,1-3H3,(H,25,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 163 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-naltrindole binding to human Opioid receptor delta 1 in CHO cells |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50086367
(3-(3-Hydroxy-phenyl)-2,2-dimethyl-3-methylamino-N-...)Show InChI InChI=1S/C20H26N2O2/c1-20(2,18(21-3)16-10-7-11-17(23)14-16)19(24)22-13-12-15-8-5-4-6-9-15/h4-11,14,18,21,23H,12-13H2,1-3H3,(H,22,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 176 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-naltrindole binding to human Opioid receptor delta 1 in CHO cells |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50086358
(CHEMBL347316 | N-Cyclopropylmethyl-3-(3-hydroxy-ph...)Show InChI InChI=1S/C16H24N2O2/c1-16(2,15(20)18-10-11-7-8-11)14(17-3)12-5-4-6-13(19)9-12/h4-6,9,11,14,17,19H,7-8,10H2,1-3H3,(H,18,20) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 364 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-DAMGO binding to rat Opioid receptor mu 1 |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50086362
(CHEMBL149143 | N-Benzyl-2,2-dimethyl-3-methylamino...)Show InChI InChI=1S/C19H24N2O/c1-19(2,17(20-3)16-12-8-5-9-13-16)18(22)21-14-15-10-6-4-7-11-15/h4-13,17,20H,14H2,1-3H3,(H,21,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 467 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]U-69,593 binding to human Opioid receptor kappa 1 expressed in HEK 293 cells |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50086363
(3-(Cyclopropylmethyl-methyl-amino)-3-(3-hydroxy-ph...)Show SMILES CN(CC1CC1)C(c1cccc(O)c1)C(C)(C)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C24H32N2O2/c1-24(2,23(28)25-15-14-18-8-5-4-6-9-18)22(26(3)17-19-12-13-19)20-10-7-11-21(27)16-20/h4-11,16,19,22,27H,12-15,17H2,1-3H3,(H,25,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 710 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-naltrindole binding to human Opioid receptor delta 1 in CHO cells |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50086358
(CHEMBL347316 | N-Cyclopropylmethyl-3-(3-hydroxy-ph...)Show InChI InChI=1S/C16H24N2O2/c1-16(2,15(20)18-10-11-7-8-11)14(17-3)12-5-4-6-13(19)9-12/h4-6,9,11,14,17,19H,7-8,10H2,1-3H3,(H,18,20) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 781 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-naltrindole binding to human Opioid receptor delta 1 in CHO cells |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50086360
(CHEMBL347531 | N-Cyclohexylmethyl-3-(3-hydroxy-phe...)Show InChI InChI=1S/C19H30N2O2/c1-19(2,17(20-3)15-10-7-11-16(22)12-15)18(23)21-13-14-8-5-4-6-9-14/h7,10-12,14,17,20,22H,4-6,8-9,13H2,1-3H3,(H,21,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 881 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-naltrindole binding to human Opioid receptor delta 1 in CHO cells |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50086362
(CHEMBL149143 | N-Benzyl-2,2-dimethyl-3-methylamino...)Show InChI InChI=1S/C19H24N2O/c1-19(2,17(20-3)16-12-8-5-9-13-16)18(22)21-14-15-10-6-4-7-11-15/h4-13,17,20H,14H2,1-3H3,(H,21,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-naltrindole binding to human Opioid receptor delta 1 in CHO cells |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50086364
(CHEMBL146750 | N-Benzyl-3-(3-hydroxy-phenyl)-2,2-d...)Show InChI InChI=1S/C19H24N2O2/c1-19(2,17(20-3)15-10-7-11-16(22)12-15)18(23)21-13-14-8-5-4-6-9-14/h4-12,17,20,22H,13H2,1-3H3,(H,21,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-naltrindole binding to human Opioid receptor delta 1 in CHO cells |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50086365
(3-(Butyl-methyl-amino)-3-(3-hydroxy-phenyl)-2,2-di...)Show SMILES CCCCN(C)C(c1cccc(O)c1)C(C)(C)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C24H34N2O2/c1-5-6-17-26(4)22(20-13-10-14-21(27)18-20)24(2,3)23(28)25-16-15-19-11-8-7-9-12-19/h7-14,18,22,27H,5-6,15-17H2,1-4H3,(H,25,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-naltrindole binding to human Opioid receptor delta 1 in CHO cells |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50086359
(CHEMBL147191 | N-Cyclohexylmethyl-2,2-dimethyl-3-m...)Show InChI InChI=1S/C19H30N2O/c1-19(2,17(20-3)16-12-8-5-9-13-16)18(22)21-14-15-10-6-4-7-11-15/h5,8-9,12-13,15,17,20H,4,6-7,10-11,14H2,1-3H3,(H,21,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-naltrindole binding to human Opioid receptor delta 1 in CHO cells |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50086357
(2,2-Dimethyl-3-methylamino-N-phenethyl-3-phenyl-pr...)Show InChI InChI=1S/C20H26N2O/c1-20(2,18(21-3)17-12-8-5-9-13-17)19(23)22-15-14-16-10-6-4-7-11-16/h4-13,18,21H,14-15H2,1-3H3,(H,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-naltrindole binding to human Opioid receptor delta 1 in CHO cells |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50086366
(3-(3-Hydroxy-phenyl)-2,2-dimethyl-3-methylamino-N-...)Show InChI InChI=1S/C21H28N2O2/c1-21(2,19(22-3)17-12-7-13-18(24)15-17)20(25)23-14-8-11-16-9-5-4-6-10-16/h4-7,9-10,12-13,15,19,22,24H,8,11,14H2,1-3H3,(H,23,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Inhibition of [3H]-naltrindole binding to human Opioid receptor delta 1 in CHO cells |
Bioorg Med Chem Lett 10: 523-6 (2000)
BindingDB Entry DOI: 10.7270/Q2BG2N79 |
More data for this
Ligand-Target Pair | |
Search and Browse
