Compile Data Set for Download or QSAR

Found 31 hits Enz. Inhib. hit(s) with all data for entry = 50010129   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091385 (1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-ethano...) Show SMILES CC(N=O)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C14H17N3O2/c1-11(17-18)12-4-6-14(7-5-12)19-8-2-3-13-9-15-10-16-13/h4-7,9-11H,2-3,8H2,1H3,(H,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091373 (1-{2-Fluoro-4-[3-(1H-imidazol-4-yl)-propoxy]-pheny...) Show SMILES CC(N=O)c1ccc(OCCCc2cnc[nH]2)cc1F Show InChI InChI=1S/C14H16FN3O2/c1-10(18-19)13-5-4-12(7-14(13)15)20-6-2-3-11-8-16-9-17-11/h4-5,7-10H,2-3,6H2,1H3,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091396 (4-[3-(1H-Imidazol-4-yl)-propoxy]-benzaldehyde oxim...) Show SMILES O=NCc1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C13H15N3O2/c17-16-8-11-3-5-13(6-4-11)18-7-1-2-12-9-14-10-15-12/h3-6,9-10H,1-2,7-8H2,(H,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091382 (CHEMBL324724 | N-Hydroxy-4-[3-(1H-imidazol-4-yl)-p...) Show SMILES ONC(=N)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C13H16N4O2/c14-13(17-18)10-3-5-12(6-4-10)19-7-1-2-11-8-15-9-16-11/h3-6,8-9,18H,1-2,7H2,(H2,14,17)(H,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM27213 (4-[3-(4-cyclopropanecarbonylphenoxy)propyl]-1H-imi...) Show SMILES O=C(C1CC1)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C16H18N2O2/c19-16(12-3-4-12)13-5-7-15(8-6-13)20-9-1-2-14-10-17-11-18-14/h5-8,10-12H,1-4,9H2,(H,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	0.490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091386 (1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-ethano...) Show SMILES CC(=O)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C14H16N2O2/c1-11(17)12-4-6-14(7-5-12)18-8-2-3-13-9-15-10-16-13/h4-7,9-10H,2-3,8H2,1H3,(H,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091372 (CHEMBL322481 | N-(1-{4-[3-(1H-Imidazol-4-yl)-propo...) Show SMILES CC(NO)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C14H19N3O2/c1-11(17-18)12-4-6-14(7-5-12)19-8-2-3-13-9-15-10-16-13/h4-7,9-11,17-18H,2-3,8H2,1H3,(H,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.930	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091371 (1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-2-methyl-pheny...) Show SMILES CC(N=O)c1ccc(OCCCc2cnc[nH]2)cc1C Show InChI InChI=1S/C15H19N3O2/c1-11-8-14(5-6-15(11)12(2)18-19)20-7-3-4-13-9-16-10-17-13/h5-6,8-10,12H,3-4,7H2,1-2H3,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091384 (4-[3-(1H-Imidazol-4-yl)-propoxy]-benzoic acid hydr...) Show SMILES NNC(=O)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C13H16N4O2/c14-17-13(18)10-3-5-12(6-4-10)19-7-1-2-11-8-15-9-16-11/h3-6,8-9H,1-2,7,14H2,(H,15,16)(H,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091375 (1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-3-methyl-pheny...) Show SMILES CC(N=O)c1ccc(OCCCc2cnc[nH]2)c(C)c1 Show InChI InChI=1S/C15H19N3O2/c1-11-8-13(12(2)18-19)5-6-15(11)20-7-3-4-14-9-16-10-17-14/h5-6,8-10,12H,3-4,7H2,1-2H3,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091383 (1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-propan...) Show SMILES CCC(N=O)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C15H19N3O2/c1-2-15(18-19)12-5-7-14(8-6-12)20-9-3-4-13-10-16-11-17-13/h5-8,10-11,15H,2-4,9H2,1H3,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091389 (4-[3-(1H-Imidazol-4-yl)-propoxy]-benzoic acid meth...) Show SMILES COC(=O)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C14H16N2O3/c1-18-14(17)11-4-6-13(7-5-11)19-8-2-3-12-9-15-10-16-12/h4-7,9-10H,2-3,8H2,1H3,(H,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM22914 (CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...) Show SMILES S=C(NC1CCCCC1)N1CCC(CC1)c1cnc[nH]1 Show InChI InChI=1S/C15H24N4S/c20-15(18-13-4-2-1-3-5-13)19-8-6-12(7-9-19)14-10-16-11-17-14/h10-13H,1-9H2,(H,16,17)(H,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091376 (CHEMBL116270 | CHEMBL80348 | Cyclopropyl-{4-[3-(1H...) Show SMILES O=NC(C1CC1)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C16H19N3O2/c20-19-16(12-3-4-12)13-5-7-15(8-6-13)21-9-1-2-14-10-17-11-18-14/h5-8,10-12,16H,1-4,9H2,(H,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091398 (1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-butan-...) Show SMILES CCCC(N=O)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C16H21N3O2/c1-2-4-16(19-20)13-6-8-15(9-7-13)21-10-3-5-14-11-17-12-18-14/h6-9,11-12,16H,2-5,10H2,1H3,(H,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091397 (1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-pentan...) Show SMILES CCCCC(N=O)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C17H23N3O2/c1-2-3-6-17(20-21)14-7-9-16(10-8-14)22-11-4-5-15-12-18-13-19-15/h7-10,12-13,17H,2-6,11H2,1H3,(H,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091388 (1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-butan-...) Show SMILES CCCC(O)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C16H22N2O2/c1-2-4-16(19)13-6-8-15(9-7-13)20-10-3-5-14-11-17-12-18-14/h6-9,11-12,16,19H,2-5,10H2,1H3,(H,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091387 (4-[3-(1H-Imidazol-4-yl)-propoxy]-benzamide; compou...) Show SMILES NC(=O)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C13H15N3O2/c14-13(17)10-3-5-12(6-4-10)18-7-1-2-11-8-15-9-16-11/h3-6,8-9H,1-2,7H2,(H2,14,17)(H,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091390 (4-[3-(4-Nitro-phenoxy)-propyl]-1H-imidazole with(0...) Show SMILES [O-][N+](=O)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C12H13N3O3/c16-15(17)11-3-5-12(6-4-11)18-7-1-2-10-8-13-9-14-10/h3-6,8-9H,1-2,7H2,(H,13,14)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091378 (1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-ethano...) Show SMILES CC(O)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C14H18N2O2/c1-11(17)12-4-6-14(7-5-12)18-8-2-3-13-9-15-10-16-13/h4-7,9-11,17H,2-3,8H2,1H3,(H,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091393 ((4-(3-(1H-imidazol-4-yl)propyloxy)phenyl)ethanone ...) Show SMILES CC(=NNC(N)=O)c1ccc(OCCCc2cnc[nH]2)cc1 |w:2.2| Show InChI InChI=1S/C15H19N5O2/c1-11(19-20-15(16)21)12-4-6-14(7-5-12)22-8-2-3-13-9-17-10-18-13/h4-7,9-10H,2-3,8H2,1H3,(H,17,18)(H3,16,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	8.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091370 (1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-hexan-...) Show SMILES CCCCCC(N=O)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C18H25N3O2/c1-2-3-4-7-18(21-22)15-8-10-17(11-9-15)23-12-5-6-16-13-19-14-20-16/h8-11,13-14,18H,2-7,12H2,1H3,(H,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091392 (4-[3-(1H-Imidazol-4-yl)-propoxy]-benzaldehyde O-me...) Show SMILES CO\N=C\c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C14H17N3O2/c1-18-17-9-12-4-6-14(7-5-12)19-8-2-3-13-10-15-11-16-13/h4-7,9-11H,2-3,8H2,1H3,(H,15,16)/b17-9+	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091394 (1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-ethano...) Show SMILES C\C(=N/OCc1ccccc1)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C21H23N3O2/c1-17(24-26-15-18-6-3-2-4-7-18)19-9-11-21(12-10-19)25-13-5-8-20-14-22-16-23-20/h2-4,6-7,9-12,14,16H,5,8,13,15H2,1H3,(H,22,23)/b24-17+	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091377 (1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-ethano...) Show SMILES CO\N=C(/C)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C15H19N3O2/c1-12(18-19-2)13-5-7-15(8-6-13)20-9-3-4-14-10-16-11-17-14/h5-8,10-11H,3-4,9H2,1-2H3,(H,16,17)/b18-12+	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091380 (1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-2-meth...) Show SMILES CC(C)C(O)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C16H22N2O2/c1-12(2)16(19)13-5-7-15(8-6-13)20-9-3-4-14-10-17-11-18-14/h5-8,10-12,16,19H,3-4,9H2,1-2H3,(H,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091391 (CHEMBL115169 | {4-[3-(1H-Imidazol-4-yl)-propoxy]-p...) Show SMILES O=C(N1CCCC1)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C17H21N3O2/c21-17(20-9-1-2-10-20)14-5-7-16(8-6-14)22-11-3-4-15-12-18-13-19-15/h5-8,12-13H,1-4,9-11H2,(H,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091374 (CHEMBL326993 | {4-[3-(1H-Imidazol-4-yl)-propoxy]-p...) Show SMILES N#CCc1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C14H15N3O/c15-8-7-12-3-5-14(6-4-12)18-9-1-2-13-10-16-11-17-13/h3-6,10-11H,1-2,7,9H2,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091395 (4-[3-(1H-Imidazol-4-yl)-propoxy]-N,N-dimethyl-benz...) Show SMILES CN(C)S(=O)(=O)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C14H19N3O3S/c1-17(2)21(18,19)14-7-5-13(6-8-14)20-9-3-4-12-10-15-11-16-12/h5-8,10-11H,3-4,9H2,1-2H3,(H,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	77	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091381 (1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-3,3-di...) Show SMILES CC(C)(C)CC(N=O)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C18H25N3O2/c1-18(2,3)11-17(21-22)14-6-8-16(9-7-14)23-10-4-5-15-12-19-13-20-15/h6-9,12-13,17H,4-5,10-11H2,1-3H3,(H,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50091379 (1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-2-methoxy-phen...) Show SMILES COc1cc(OCCCc2cnc[nH]2)ccc1C(C)N=O Show InChI InChI=1S/C15H19N3O3/c1-11(18-19)14-6-5-13(8-15(14)20-2)21-7-3-4-12-9-16-10-17-12/h5-6,8-11H,3-4,7H2,1-2H3,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	371	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.				J Med Chem 43: 3335-43 (2000) BindingDB Entry DOI: 10.7270/Q2RR1XGV
					More data for this Ligand-Target Pair