Compile Data Set for Download or QSAR

Found 45 hits Enz. Inhib. hit(s) with all data for entry = 50046286   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50103575 (CHEMBL3337585) Show SMILES COc1ccc(cc1N(C)C)C(=O)N1CCC2(CC1)Nc1cc(ccc1-n1cccc21)C(F)(F)F Show InChI InChI=1S/C26H27F3N4O2/c1-31(2)21-15-17(6-9-22(21)35-3)24(34)32-13-10-25(11-14-32)23-5-4-12-33(23)20-8-7-18(26(27,28)29)16-19(20)30-25/h4-9,12,15-16,30H,10-11,13-14H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50057402 (CHEMBL3322777) Show SMILES COc1ccc-2c(NC3(CCN(CC3)C(=O)c3ccc(OC)c(c3)N(C)C)c3cccn-23)c1 Show InChI InChI=1S/C26H30N4O3/c1-28(2)22-16-18(7-10-23(22)33-4)25(31)29-14-11-26(12-15-29)24-6-5-13-30(24)21-9-8-19(32-3)17-20(21)27-26/h5-10,13,16-17,27H,11-12,14-15H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50103573 (CHEMBL3337583) Show SMILES COc1ccc(cc1N(C)C)C(=O)N1CCC2(CC1)Nc1cc(OC(F)(F)F)ccc1-n1cccc21 Show InChI InChI=1S/C26H27F3N4O3/c1-31(2)21-15-17(6-9-22(21)35-3)24(34)32-13-10-25(11-14-32)23-5-4-12-33(23)20-8-7-18(16-19(20)30-25)36-26(27,28)29/h4-9,12,15-16,30H,10-11,13-14H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50103586 (CHEMBL3337596) Show SMILES CCCCc1nc2cc(ccc2o1)C(=O)N1CCC2(CC1)Nc1cc(OC)ccc1-n1cccc21 Show InChI InChI=1S/C28H30N4O3/c1-3-4-7-26-29-22-17-19(8-11-24(22)35-26)27(33)31-15-12-28(13-16-31)25-6-5-14-32(25)23-10-9-20(34-2)18-21(23)30-28/h5-6,8-11,14,17-18,30H,3-4,7,12-13,15-16H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50103574 (CHEMBL3337584) Show SMILES COc1ccc(cc1N(C)C)C(=O)N1CCC2(CC1)Nc1cc(OC(F)F)ccc1-n1cccc21 Show InChI InChI=1S/C26H28F2N4O3/c1-30(2)21-15-17(6-9-22(21)34-3)24(33)31-13-10-26(11-14-31)23-5-4-12-32(23)20-8-7-18(35-25(27)28)16-19(20)29-26/h4-9,12,15-16,25,29H,10-11,13-14H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50103591 (CHEMBL3337601) Show SMILES COc1ccc-2c(NC3(CCN(CC3)C(=O)c3ccc4n(C)ccc4c3)c3cccn-23)c1 Show InChI InChI=1S/C26H26N4O2/c1-28-13-9-18-16-19(5-7-22(18)28)25(31)29-14-10-26(11-15-29)24-4-3-12-30(24)23-8-6-20(32-2)17-21(23)27-26/h3-9,12-13,16-17,27H,10-11,14-15H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50103589 (CHEMBL3337599) Show SMILES COc1ccc-2c(NC3(CCN(CC3)C(=O)c3ccc4ccccc4n3)c3cccn-23)c1 Show InChI InChI=1S/C26H24N4O2/c1-32-19-9-11-23-22(17-19)28-26(24-7-4-14-30(23)24)12-15-29(16-13-26)25(31)21-10-8-18-5-2-3-6-20(18)27-21/h2-11,14,17,28H,12-13,15-16H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50103576 (CHEMBL3337586) Show SMILES COCCOc1ccc-2c(NC3(CCN(CC3)C(=O)c3ccc(OC)c(c3)N(C)C)c3cccn-23)c1 Show InChI InChI=1S/C28H34N4O4/c1-30(2)24-18-20(7-10-25(24)35-4)27(33)31-14-11-28(12-15-31)26-6-5-13-32(26)23-9-8-21(19-22(23)29-28)36-17-16-34-3/h5-10,13,18-19,29H,11-12,14-17H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50103587 (CHEMBL3337597) Show SMILES COc1ccc-2c(NC3(CCN(CC3)C(=O)c3ccc4ncccc4c3)c3cccn-23)c1 Show InChI InChI=1S/C26H24N4O2/c1-32-20-7-9-23-22(17-20)28-26(24-5-3-13-30(23)24)10-14-29(15-11-26)25(31)19-6-8-21-18(16-19)4-2-12-27-21/h2-9,12-13,16-17,28H,10-11,14-15H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50103584 (CHEMBL3337595) Show SMILES COc1ccc-2c(NC3(CCN(CC3)C(=O)c3ccc(OC)c(c3)N3CCCC3)c3cccn-23)c1 Show InChI InChI=1S/C28H32N4O3/c1-34-21-8-9-23-22(19-21)29-28(26-6-5-15-32(23)26)11-16-31(17-12-28)27(33)20-7-10-25(35-2)24(18-20)30-13-3-4-14-30/h5-10,15,18-19,29H,3-4,11-14,16-17H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50103592 (CHEMBL3337602) Show SMILES COc1ccc-2c(NC3(CCN(CC3)C(=O)c3ccc4n(C)ncc4c3)c3cccn-23)c1 Show InChI InChI=1S/C25H25N5O2/c1-28-21-7-5-17(14-18(21)16-26-28)24(31)29-12-9-25(10-13-29)23-4-3-11-30(23)22-8-6-19(32-2)15-20(22)27-25/h3-8,11,14-16,27H,9-10,12-13H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50103577 (CHEMBL3337587) Show SMILES COc1cc2NC3(CCN(CC3)C(=O)c3ccc(OC)c(c3)N(C)C)c3cccn3-c2cc1F Show InChI InChI=1S/C26H29FN4O3/c1-29(2)21-14-17(7-8-22(21)33-3)25(32)30-12-9-26(10-13-30)24-6-5-11-31(24)20-15-18(27)23(34-4)16-19(20)28-26/h5-8,11,14-16,28H,9-10,12-13H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50103578 (CHEMBL3337589) Show SMILES COc1ccc-2c(N[C@@]3(CCN(C[C@@H]3C)C(=O)c3ccc(OC)c(c3)N(C)C)c3cccn-23)c1 |r| Show InChI InChI=1S/C27H32N4O3/c1-18-17-30(26(32)19-8-11-24(34-5)23(15-19)29(2)3)14-12-27(18)25-7-6-13-31(25)22-10-9-20(33-4)16-21(22)28-27/h6-11,13,15-16,18,28H,12,14,17H2,1-5H3/t18-,27+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	103	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50103585 (CHEMBL3337594) Show SMILES COc1ccc-2c(NC3(CCN(CC3)C(=O)c3ccc4OCCN(C)c4c3)c3cccn-23)c1 Show InChI InChI=1S/C26H28N4O3/c1-28-14-15-33-23-8-5-18(16-22(23)28)25(31)29-12-9-26(10-13-29)24-4-3-11-30(24)21-7-6-19(32-2)17-20(21)27-26/h3-8,11,16-17,27H,9-10,12-15H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	106	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50103588 (CHEMBL3337598) Show SMILES COc1ccc-2c(NC3(CCN(CC3)C(=O)c3cccc4ncccc34)c3cccn-23)c1 Show InChI InChI=1S/C26H24N4O2/c1-32-18-9-10-23-22(17-18)28-26(24-8-4-14-30(23)24)11-15-29(16-12-26)25(31)20-5-2-7-21-19(20)6-3-13-27-21/h2-10,13-14,17,28H,11-12,15-16H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	109	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50103584 (CHEMBL3337595) Show SMILES COc1ccc-2c(NC3(CCN(CC3)C(=O)c3ccc(OC)c(c3)N3CCCC3)c3cccn-23)c1 Show InChI InChI=1S/C28H32N4O3/c1-34-21-8-9-23-22(19-21)29-28(26-6-5-15-32(23)26)11-16-31(17-12-28)27(33)20-7-10-25(35-2)24(18-20)30-13-3-4-14-30/h5-10,15,18-19,29H,3-4,11-14,16-17H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	118	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50103590 (CHEMBL3337600) Show SMILES COc1ccc-2c(NC3(CCN(CC3)C(=O)c3ccc4cccnc4c3)c3cccn-23)c1 Show InChI InChI=1S/C26H24N4O2/c1-32-20-8-9-23-22(17-20)28-26(24-5-3-13-30(23)24)10-14-29(15-11-26)25(31)19-7-6-18-4-2-12-27-21(18)16-19/h2-9,12-13,16-17,28H,10-11,14-15H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	124	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50103573 (CHEMBL3337583) Show SMILES COc1ccc(cc1N(C)C)C(=O)N1CCC2(CC1)Nc1cc(OC(F)(F)F)ccc1-n1cccc21 Show InChI InChI=1S/C26H27F3N4O3/c1-31(2)21-15-17(6-9-22(21)35-3)24(34)32-13-10-25(11-14-32)23-5-4-12-33(23)20-8-7-18(16-19(20)30-25)36-26(27,28)29/h4-9,12,15-16,30H,10-11,13-14H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	181	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50103575 (CHEMBL3337585) Show SMILES COc1ccc(cc1N(C)C)C(=O)N1CCC2(CC1)Nc1cc(ccc1-n1cccc21)C(F)(F)F Show InChI InChI=1S/C26H27F3N4O2/c1-31(2)21-15-17(6-9-22(21)35-3)24(34)32-13-10-25(11-14-32)23-5-4-12-33(23)20-8-7-18(26(27,28)29)16-19(20)30-25/h4-9,12,15-16,30H,10-11,13-14H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	217	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50103583 (CHEMBL3337588) Show SMILES COc1ccc-2c(N[C@]3(CCN([C@H](C)C3)C(=O)c3ccc(OC)c(c3)N(C)C)c3cccn-23)c1 |r| Show InChI InChI=1S/C27H32N4O3/c1-18-17-27(25-7-6-13-31(25)22-10-9-20(33-4)16-21(22)28-27)12-14-30(18)26(32)19-8-11-24(34-5)23(15-19)29(2)3/h6-11,13,15-16,18,28H,12,14,17H2,1-5H3/t18-,27+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	315	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50057402 (CHEMBL3322777) Show SMILES COc1ccc-2c(NC3(CCN(CC3)C(=O)c3ccc(OC)c(c3)N(C)C)c3cccn-23)c1 Show InChI InChI=1S/C26H30N4O3/c1-28(2)22-16-18(7-10-23(22)33-4)25(31)29-14-11-26(12-15-29)24-6-5-13-30(24)21-9-8-19(32-3)17-20(21)27-26/h5-10,13,16-17,27H,11-12,14-15H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	331	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 expressed in HEK293 cells by voltage clamp assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50103574 (CHEMBL3337584) Show SMILES COc1ccc(cc1N(C)C)C(=O)N1CCC2(CC1)Nc1cc(OC(F)F)ccc1-n1cccc21 Show InChI InChI=1S/C26H28F2N4O3/c1-30(2)21-15-17(6-9-22(21)34-3)24(33)31-13-10-26(11-14-31)23-5-4-12-32(23)20-8-7-18(35-25(27)28)16-19(20)29-26/h4-9,12,15-16,25,29H,10-11,13-14H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50103577 (CHEMBL3337587) Show SMILES COc1cc2NC3(CCN(CC3)C(=O)c3ccc(OC)c(c3)N(C)C)c3cccn3-c2cc1F Show InChI InChI=1S/C26H29FN4O3/c1-29(2)21-14-17(7-8-22(21)33-3)25(32)30-12-9-26(10-13-30)24-6-5-11-31(24)20-15-18(27)23(34-4)16-19(20)28-26/h5-8,11,14-16,28H,9-10,12-13H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	358	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50103589 (CHEMBL3337599) Show SMILES COc1ccc-2c(NC3(CCN(CC3)C(=O)c3ccc4ccccc4n3)c3cccn-23)c1 Show InChI InChI=1S/C26H24N4O2/c1-32-19-9-11-23-22(17-19)28-26(24-7-4-14-30(23)24)12-15-29(16-13-26)25(31)21-10-8-18-5-2-3-6-20(18)27-21/h2-11,14,17,28H,12-13,15-16H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	419	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50103581 (CHEMBL3337592) Show SMILES COc1ccc-2c(NC3(CC4CN(CC4C3)C(=O)c3ccc(OC)c(c3)N(C)C)c3cccn-23)c1 Show InChI InChI=1S/C28H32N4O3/c1-30(2)24-12-18(7-10-25(24)35-4)27(33)31-16-19-14-28(15-20(19)17-31)26-6-5-11-32(26)23-9-8-21(34-3)13-22(23)29-28/h5-13,19-20,29H,14-17H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	439	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50103578 (CHEMBL3337589) Show SMILES COc1ccc-2c(N[C@@]3(CCN(C[C@@H]3C)C(=O)c3ccc(OC)c(c3)N(C)C)c3cccn-23)c1 |r| Show InChI InChI=1S/C27H32N4O3/c1-18-17-30(26(32)19-8-11-24(34-5)23(15-19)29(2)3)14-12-27(18)25-7-6-13-31(25)22-10-9-20(33-4)16-21(22)28-27/h6-11,13,15-16,18,28H,12,14,17H2,1-5H3/t18-,27+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	519	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50057402 (CHEMBL3322777) Show SMILES COc1ccc-2c(NC3(CCN(CC3)C(=O)c3ccc(OC)c(c3)N(C)C)c3cccn-23)c1 Show InChI InChI=1S/C26H30N4O3/c1-28(2)22-16-18(7-10-23(22)33-4)25(31)29-14-11-26(12-15-29)24-6-5-13-30(24)21-9-8-19(32-3)17-20(21)27-26/h5-10,13,16-17,27H,11-12,14-15H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	572	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50103580 (CHEMBL3337591) Show SMILES COc1ccc-2c(NC3(CCCN(CC3)C(=O)c3ccc(OC)c(c3)N(C)C)c3cccn-23)c1 Show InChI InChI=1S/C27H32N4O3/c1-29(2)23-17-19(8-11-24(23)34-4)26(32)30-14-6-12-27(13-16-30)25-7-5-15-31(25)22-10-9-20(33-3)18-21(22)28-27/h5,7-11,15,17-18,28H,6,12-14,16H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	656	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50103587 (CHEMBL3337597) Show SMILES COc1ccc-2c(NC3(CCN(CC3)C(=O)c3ccc4ncccc4c3)c3cccn-23)c1 Show InChI InChI=1S/C26H24N4O2/c1-32-20-7-9-23-22(17-20)28-26(24-5-3-13-30(23)24)10-14-29(15-11-26)25(31)19-6-8-21-18(16-19)4-2-12-27-21/h2-9,12-13,16-17,28H,10-11,14-15H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 expressed in HEK293 cells by voltage clamp assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50103587 (CHEMBL3337597) Show SMILES COc1ccc-2c(NC3(CCN(CC3)C(=O)c3ccc4ncccc4c3)c3cccn-23)c1 Show InChI InChI=1S/C26H24N4O2/c1-32-20-7-9-23-22(17-20)28-26(24-5-3-13-30(23)24)10-14-29(15-11-26)25(31)19-6-8-21-18(16-19)4-2-12-27-21/h2-9,12-13,16-17,28H,10-11,14-15H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50103585 (CHEMBL3337594) Show SMILES COc1ccc-2c(NC3(CCN(CC3)C(=O)c3ccc4OCCN(C)c4c3)c3cccn-23)c1 Show InChI InChI=1S/C26H28N4O3/c1-28-14-15-33-23-8-5-18(16-22(23)28)25(31)29-12-9-26(10-13-29)24-4-3-11-30(24)21-7-6-19(32-2)17-20(21)27-26/h3-8,11,16-17,27H,9-10,12-15H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50103586 (CHEMBL3337596) Show SMILES CCCCc1nc2cc(ccc2o1)C(=O)N1CCC2(CC1)Nc1cc(OC)ccc1-n1cccc21 Show InChI InChI=1S/C28H30N4O3/c1-3-4-7-26-29-22-17-19(8-11-24(22)35-26)27(33)31-15-12-28(13-16-31)25-6-5-14-32(25)23-10-9-20(34-2)18-21(23)30-28/h5-6,8-11,14,17-18,30H,3-4,7,12-13,15-16H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50103591 (CHEMBL3337601) Show SMILES COc1ccc-2c(NC3(CCN(CC3)C(=O)c3ccc4n(C)ccc4c3)c3cccn-23)c1 Show InChI InChI=1S/C26H26N4O2/c1-28-13-9-18-16-19(5-7-22(18)28)25(31)29-14-10-26(11-15-29)24-4-3-12-30(24)23-8-6-20(32-2)17-21(23)27-26/h3-9,12-13,16-17,27H,10-11,14-15H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50103590 (CHEMBL3337600) Show SMILES COc1ccc-2c(NC3(CCN(CC3)C(=O)c3ccc4cccnc4c3)c3cccn-23)c1 Show InChI InChI=1S/C26H24N4O2/c1-32-20-8-9-23-22(17-20)28-26(24-5-3-13-30(23)24)10-14-29(15-11-26)25(31)19-7-6-18-4-2-12-27-21(18)16-19/h2-9,12-13,16-17,28H,10-11,14-15H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50103576 (CHEMBL3337586) Show SMILES COCCOc1ccc-2c(NC3(CCN(CC3)C(=O)c3ccc(OC)c(c3)N(C)C)c3cccn-23)c1 Show InChI InChI=1S/C28H34N4O4/c1-30(2)24-18-20(7-10-25(24)35-4)27(33)31-14-11-28(12-15-31)26-6-5-13-32(26)23-9-8-21(19-22(23)29-28)36-17-16-34-3/h5-10,13,18-19,29H,11-12,14-17H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50103581 (CHEMBL3337592) Show SMILES COc1ccc-2c(NC3(CC4CN(CC4C3)C(=O)c3ccc(OC)c(c3)N(C)C)c3cccn-23)c1 Show InChI InChI=1S/C28H32N4O3/c1-30(2)24-12-18(7-10-25(24)35-4)27(33)31-16-19-14-28(15-20(19)17-31)26-6-5-11-32(26)23-9-8-21(34-3)13-22(23)29-28/h5-13,19-20,29H,14-17H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50103592 (CHEMBL3337602) Show SMILES COc1ccc-2c(NC3(CCN(CC3)C(=O)c3ccc4n(C)ncc4c3)c3cccn-23)c1 Show InChI InChI=1S/C25H25N5O2/c1-28-21-7-5-17(14-18(21)16-26-28)24(31)29-12-9-25(10-13-29)23-4-3-11-30(23)22-8-6-19(32-2)15-20(22)27-25/h3-8,11,14-16,27H,9-10,12-13H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50103588 (CHEMBL3337598) Show SMILES COc1ccc-2c(NC3(CCN(CC3)C(=O)c3cccc4ncccc34)c3cccn-23)c1 Show InChI InChI=1S/C26H24N4O2/c1-32-18-9-10-23-22(17-18)28-26(24-8-4-14-30(23)24)11-15-29(16-12-26)25(31)20-5-2-7-21-19(20)6-3-13-27-21/h2-10,13-14,17,28H,11-12,15-16H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50103580 (CHEMBL3337591) Show SMILES COc1ccc-2c(NC3(CCCN(CC3)C(=O)c3ccc(OC)c(c3)N(C)C)c3cccn-23)c1 Show InChI InChI=1S/C27H32N4O3/c1-29(2)23-17-19(8-11-24(23)34-4)26(32)30-14-6-12-27(13-16-30)25-7-5-15-31(25)22-10-9-20(33-3)18-21(22)28-27/h5,7-11,15,17-18,28H,6,12-14,16H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50103583 (CHEMBL3337588) Show SMILES COc1ccc-2c(N[C@]3(CCN([C@H](C)C3)C(=O)c3ccc(OC)c(c3)N(C)C)c3cccn-23)c1 |r| Show InChI InChI=1S/C27H32N4O3/c1-18-17-27(25-7-6-13-31(25)22-10-9-20(33-4)16-21(22)28-27)12-14-30(18)26(32)19-8-11-24(34-5)23(15-19)29(2)3/h6-11,13,15-16,18,28H,12,14,17H2,1-5H3/t18-,27+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50103579 (CHEMBL3337590) Show SMILES COc1ccc-2c(NC3(CN(C3)C(=O)c3ccc4ncccc4c3)c3cccn-23)c1 Show InChI InChI=1S/C24H20N4O2/c1-30-18-7-9-21-20(13-18)26-24(22-5-3-11-28(21)22)14-27(15-24)23(29)17-6-8-19-16(12-17)4-2-10-25-19/h2-13,26H,14-15H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50057402 (CHEMBL3322777) Show SMILES COc1ccc-2c(NC3(CCN(CC3)C(=O)c3ccc(OC)c(c3)N(C)C)c3cccn-23)c1 Show InChI InChI=1S/C26H30N4O3/c1-28(2)22-16-18(7-10-23(22)33-4)25(31)29-14-11-26(12-15-29)24-6-5-13-30(24)21-9-8-19(32-3)17-20(21)27-26/h5-10,13,16-17,27H,11-12,14-15H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 expressed in HEK293 cells by voltage clamp assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50103582 (CHEMBL3337593) Show SMILES COc1ccc-2c(NC3(CCC(CC3)NC(=O)c3ccc(OC)c(c3)N(C)C)c3cccn-23)c1 |(2.7,-10.77,;4.03,-9.99,;5.36,-10.76,;5.36,-12.31,;6.7,-13.08,;8.03,-12.3,;8.03,-10.76,;9.36,-9.98,;10.7,-10.76,;12.03,-11.53,;13.36,-10.76,;13.36,-9.23,;12.03,-8.46,;10.7,-9.22,;14.7,-8.46,;14.7,-6.92,;13.37,-6.15,;16.04,-6.16,;16.04,-4.62,;17.37,-3.85,;18.71,-4.63,;20.04,-3.86,;21.37,-4.63,;18.7,-6.17,;17.37,-6.93,;20.03,-6.94,;20.03,-8.48,;21.37,-6.18,;10.7,-12.31,;11.84,-13.35,;11.21,-14.76,;9.67,-14.59,;9.36,-13.08,;6.69,-9.99,)| Show InChI InChI=1S/C27H32N4O3/c1-30(2)23-16-18(7-10-24(23)34-4)26(32)28-19-11-13-27(14-12-19)25-6-5-15-31(25)22-9-8-20(33-3)17-21(22)29-27/h5-10,15-17,19,29H,11-14H2,1-4H3,(H,28,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.52E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50103582 (CHEMBL3337593) Show SMILES COc1ccc-2c(NC3(CCC(CC3)NC(=O)c3ccc(OC)c(c3)N(C)C)c3cccn-23)c1 |(2.7,-10.77,;4.03,-9.99,;5.36,-10.76,;5.36,-12.31,;6.7,-13.08,;8.03,-12.3,;8.03,-10.76,;9.36,-9.98,;10.7,-10.76,;12.03,-11.53,;13.36,-10.76,;13.36,-9.23,;12.03,-8.46,;10.7,-9.22,;14.7,-8.46,;14.7,-6.92,;13.37,-6.15,;16.04,-6.16,;16.04,-4.62,;17.37,-3.85,;18.71,-4.63,;20.04,-3.86,;21.37,-4.63,;18.7,-6.17,;17.37,-6.93,;20.03,-6.94,;20.03,-8.48,;21.37,-6.18,;10.7,-12.31,;11.84,-13.35,;11.21,-14.76,;9.67,-14.59,;9.36,-13.08,;6.69,-9.99,)| Show InChI InChI=1S/C27H32N4O3/c1-30(2)23-16-18(7-10-24(23)34-4)26(32)28-19-11-13-27(14-12-19)25-6-5-15-31(25)22-9-8-20(33-3)17-21(22)29-27/h5-10,15-17,19,29H,11-14H2,1-4H3,(H,28,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50103579 (CHEMBL3337590) Show SMILES COc1ccc-2c(NC3(CN(C3)C(=O)c3ccc4ncccc4c3)c3cccn-23)c1 Show InChI InChI=1S/C24H20N4O2/c1-30-18-7-9-21-20(13-18)26-24(22-5-3-11-28(21)22)14-27(15-24)23(29)17-6-8-19-16(12-17)4-2-10-25-19/h2-13,26H,14-15H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
					More data for this Ligand-Target Pair