Compile Data Set for Download or QSAR

Found 72 hits Enz. Inhib. hit(s) with all data for entry = 50026919   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50244449 ((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2cn(C)c3ccccc23)C(=O)O1 Show InChI InChI=1S/C24H31NO5/c1-4-8-17(9-5-2)22(27)29-16-24(15-26)13-18(23(28)30-24)12-19-14-25(3)21-11-7-6-10-20(19)21/h6-7,10-12,14,17,26H,4-5,8-9,13,15-16H2,1-3H3/b18-12+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cells				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50244450 ((E)-(2-(hydroxymethyl)-5-oxo-4-(pyridin-2-ylmethyl...) Show SMILES CC(C)CC(CC(C)C)C(=O)OCC1(CO)C\C(=C/c2ccccn2)C(=O)O1 Show InChI InChI=1S/C22H31NO5/c1-15(2)9-17(10-16(3)4)20(25)27-14-22(13-24)12-18(21(26)28-22)11-19-7-5-6-8-23-19/h5-8,11,15-17,24H,9-10,12-14H2,1-4H3/b18-11+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cells				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50245022 ((E)-(2-(hydroxymethyl)-5-oxo-4-(quinolin-3-ylmethy...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2cnc3ccccc3c2)C(=O)O1 Show InChI InChI=1S/C24H29NO5/c1-3-7-18(8-4-2)22(27)29-16-24(15-26)13-20(23(28)30-24)12-17-11-19-9-5-6-10-21(19)25-14-17/h5-6,9-12,14,18,26H,3-4,7-8,13,15-16H2,1-2H3/b20-12+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cells				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50244451 ((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...) Show SMILES CC(C)CC(CC(C)C)C(=O)OCC1(CO)C\C(=C/c2cn(C)c3ccccc23)C(=O)O1 Show InChI InChI=1S/C26H35NO5/c1-17(2)10-19(11-18(3)4)24(29)31-16-26(15-28)13-20(25(30)32-26)12-21-14-27(5)23-9-7-6-8-22(21)23/h6-9,12,14,17-19,28H,10-11,13,15-16H2,1-5H3/b20-12+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cells				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50244979 ((E)-(2-(hydroxymethyl)-5-oxo-4-(pyridin-2-ylmethyl...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2ccccn2)C(=O)O1 Show InChI InChI=1S/C20H27NO5/c1-3-7-15(8-4-2)18(23)25-14-20(13-22)12-16(19(24)26-20)11-17-9-5-6-10-21-17/h5-6,9-11,15,22H,3-4,7-8,12-14H2,1-2H3/b16-11+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.720	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cells				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50244981 ((E)-(2-(hydroxymethyl)-5-oxo-4-(pyridin-3-ylmethyl...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2cccnc2)C(=O)O1 Show InChI InChI=1S/C20H27NO5/c1-3-6-16(7-4-2)18(23)25-14-20(13-22)11-17(19(24)26-20)10-15-8-5-9-21-12-15/h5,8-10,12,16,22H,3-4,6-7,11,13-14H2,1-2H3/b17-10+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cells				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50245020 ((E)-(2-(hydroxymethyl)-5-oxo-4-(quinolin-2-ylmethy...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2ccc3ccccc3n2)C(=O)O1 Show InChI InChI=1S/C24H29NO5/c1-3-7-18(8-4-2)22(27)29-16-24(15-26)14-19(23(28)30-24)13-20-12-11-17-9-5-6-10-21(17)25-20/h5-6,9-13,18,26H,3-4,7-8,14-16H2,1-2H3/b19-13+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cells				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50244481 ((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...) Show SMILES COc1ccc(cc1)C(=O)OCC1(CO)C\C(=C/c2cn(C)c3ccccc23)C(=O)O1 Show InChI InChI=1S/C24H23NO6/c1-25-13-18(20-5-3-4-6-21(20)25)11-17-12-24(14-26,31-23(17)28)15-30-22(27)16-7-9-19(29-2)10-8-16/h3-11,13,26H,12,14-15H2,1-2H3/b17-11+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cells				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50244974 ((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...) Show SMILES CN(C)c1ccc(cc1)C(=O)OCC1(CO)C\C(=C/c2cn(C)c3ccccc23)C(=O)O1 Show InChI InChI=1S/C25H26N2O5/c1-26(2)20-10-8-17(9-11-20)23(29)31-16-25(15-28)13-18(24(30)32-25)12-19-14-27(3)22-7-5-4-6-21(19)22/h4-12,14,28H,13,15-16H2,1-3H3/b18-12+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cells				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50244482 ((4-(4-nitrobenzylidene)-2-(hydroxymethyl)-5-oxo-te...) Show SMILES CN(C)c1ccc(cc1)C(=O)OCC1(CO)C\C(=C/c2ccc(cc2)[N+]([O-])=O)C(=O)O1 Show InChI InChI=1S/C22H22N2O7/c1-23(2)18-9-5-16(6-10-18)20(26)30-14-22(13-25)12-17(21(27)31-22)11-15-3-7-19(8-4-15)24(28)29/h3-11,25H,12-14H2,1-2H3/b17-11+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cells				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50245021 ((Z)-(2-(hydroxymethyl)-5-oxo-4-(quinolin-2-ylmethy...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C\c2ccc3ccccc3n2)C(=O)O1 Show InChI InChI=1S/C24H29NO5/c1-3-7-18(8-4-2)22(27)29-16-24(15-26)14-19(23(28)30-24)13-20-12-11-17-9-5-6-10-21(17)25-20/h5-6,9-13,18,26H,3-4,7-8,14-16H2,1-2H3/b19-13-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cells				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50244450 ((E)-(2-(hydroxymethyl)-5-oxo-4-(pyridin-2-ylmethyl...) Show SMILES CC(C)CC(CC(C)C)C(=O)OCC1(CO)C\C(=C/c2ccccn2)C(=O)O1 Show InChI InChI=1S/C22H31NO5/c1-15(2)9-17(10-16(3)4)20(25)27-14-22(13-24)12-18(21(26)28-22)11-19-7-5-6-8-23-19/h5-8,11,15-17,24H,9-10,12-14H2,1-4H3/b18-11+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from human recombinant PKCalpha expressed in Escherichia coli BL21-21-Gold (DE3)				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50244452 ((4-(4-nitrobenzylidene)-2-(hydroxymethyl)-5-oxo-te...) Show SMILES COc1ccc(cc1)C(=O)OCC1(CO)C\C(=C/c2ccc(cc2)[N+]([O-])=O)C(=O)O1 Show InChI InChI=1S/C21H19NO8/c1-28-18-8-4-15(5-9-18)19(24)29-13-21(12-23)11-16(20(25)30-21)10-14-2-6-17(7-3-14)22(26)27/h2-10,23H,11-13H2,1H3/b16-10+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cells				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50244448 ((E)-(2-(hydroxymethyl)-5-oxo-4-(quinolin-2-ylmethy...) Show SMILES COc1ccc(cc1)C(=O)OCC1(CO)C\C(=C/c2ccc3ccccc3n2)C(=O)O1 Show InChI InChI=1S/C24H21NO6/c1-29-20-10-7-17(8-11-20)22(27)30-15-24(14-26)13-18(23(28)31-24)12-19-9-6-16-4-2-3-5-21(16)25-19/h2-12,26H,13-15H2,1H3/b18-12+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cells				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50244926 ((E)-(2-(hydroxymethyl)-5-oxo-4-(quinolin-2-ylmethy...) Show SMILES CN(C)c1ccc(cc1)C(=O)OCC1(CO)C\C(=C/c2ccc3ccccc3n2)C(=O)O1 Show InChI InChI=1S/C25H24N2O5/c1-27(2)21-11-8-18(9-12-21)23(29)31-16-25(15-28)14-19(24(30)32-25)13-20-10-7-17-5-3-4-6-22(17)26-20/h3-13,28H,14-16H2,1-2H3/b19-13+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cells				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50245022 ((E)-(2-(hydroxymethyl)-5-oxo-4-(quinolin-3-ylmethy...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2cnc3ccccc3c2)C(=O)O1 Show InChI InChI=1S/C24H29NO5/c1-3-7-18(8-4-2)22(27)29-16-24(15-26)13-20(23(28)30-24)12-17-11-19-9-5-6-10-21(19)25-14-17/h5-6,9-12,14,18,26H,3-4,7-8,13,15-16H2,1-2H3/b20-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from human recombinant PKCalpha expressed in Escherichia coli BL21-21-Gold (DE3)				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50244983 ((E)-(2-(hydroxymethyl)-5-oxo-4-(pyridin-4-ylmethyl...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2ccncc2)C(=O)O1 Show InChI InChI=1S/C20H27NO5/c1-3-5-16(6-4-2)18(23)25-14-20(13-22)12-17(19(24)26-20)11-15-7-9-21-10-8-15/h7-11,16,22H,3-6,12-14H2,1-2H3/b17-11+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cells				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50244451 ((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...) Show SMILES CC(C)CC(CC(C)C)C(=O)OCC1(CO)C\C(=C/c2cn(C)c3ccccc23)C(=O)O1 Show InChI InChI=1S/C26H35NO5/c1-17(2)10-19(11-18(3)4)24(29)31-16-26(15-28)13-20(25(30)32-26)12-21-14-27(5)23-9-7-6-8-22(21)23/h6-9,12,14,17-19,28H,10-11,13,15-16H2,1-5H3/b20-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from human recombinant PKCalpha expressed in Escherichia coli BL21-21-Gold (DE3)				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50244479 ((E)-(2-(hydroxymethyl)-5-oxo-4-(quinolin-3-ylmethy...) Show SMILES COc1ccc(cc1)C(=O)OCC1(CO)C\C(=C/c2cnc3ccccc3c2)C(=O)O1 Show InChI InChI=1S/C24H21NO6/c1-29-20-8-6-17(7-9-20)22(27)30-15-24(14-26)12-19(23(28)31-24)11-16-10-18-4-2-3-5-21(18)25-13-16/h2-11,13,26H,12,14-15H2,1H3/b19-11+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cells				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50244473 ((E)-(2-(hydroxymethyl)-5-oxo-4-(pyridin-2-ylmethyl...) Show SMILES CN(C)c1ccc(cc1)C(=O)OCC1(CO)C\C(=C/c2ccccn2)C(=O)O1 Show InChI InChI=1S/C21H22N2O5/c1-23(2)18-8-6-15(7-9-18)19(25)27-14-21(13-24)12-16(20(26)28-21)11-17-5-3-4-10-22-17/h3-11,24H,12-14H2,1-2H3/b16-11+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cells				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50244449 ((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2cn(C)c3ccccc23)C(=O)O1 Show InChI InChI=1S/C24H31NO5/c1-4-8-17(9-5-2)22(27)29-16-24(15-26)13-18(23(28)30-24)12-19-14-25(3)21-11-7-6-10-20(19)21/h6-7,10-12,14,17,26H,4-5,8-9,13,15-16H2,1-3H3/b18-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from human recombinant PKCalpha expressed in Escherichia coli BL21-21-Gold (DE3)				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50245023 ((Z)-(2-(hydroxymethyl)-5-oxo-4-(quinolin-3-ylmethy...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C\c2cnc3ccccc3c2)C(=O)O1 Show InChI InChI=1S/C24H29NO5/c1-3-7-18(8-4-2)22(27)29-16-24(15-26)13-20(23(28)30-24)12-17-11-19-9-5-6-10-21(19)25-14-17/h5-6,9-12,14,18,26H,3-4,7-8,13,15-16H2,1-2H3/b20-12-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cells				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50244975 ((E)-(2-(hydroxymethyl)-5-oxo-4-(pyridin-2-ylmethyl...) Show SMILES COc1ccc(cc1)C(=O)OCC1(CO)C\C(=C/c2ccccn2)C(=O)O1 Show InChI InChI=1S/C20H19NO6/c1-25-17-7-5-14(6-8-17)18(23)26-13-20(12-22)11-15(19(24)27-20)10-16-4-2-3-9-21-16/h2-10,22H,11-13H2,1H3/b15-10+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cells				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50245019 ((Z)-(2-(hydroxymethyl)-5-oxo-4-(pyridin-4-ylmethyl...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C\c2ccncc2)C(=O)O1 Show InChI InChI=1S/C20H27NO5/c1-3-5-16(6-4-2)18(23)25-14-20(13-22)12-17(19(24)26-20)11-15-7-9-21-10-8-15/h7-11,16,22H,3-6,12-14H2,1-2H3/b17-11-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cells				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50245020 ((E)-(2-(hydroxymethyl)-5-oxo-4-(quinolin-2-ylmethy...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2ccc3ccccc3n2)C(=O)O1 Show InChI InChI=1S/C24H29NO5/c1-3-7-18(8-4-2)22(27)29-16-24(15-26)14-19(23(28)30-24)13-20-12-11-17-9-5-6-10-21(17)25-20/h5-6,9-13,18,26H,3-4,7-8,14-16H2,1-2H3/b19-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from human recombinant PKCalpha expressed in Escherichia coli BL21-21-Gold (DE3)				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50244476 ((E)-(2-(hydroxymethyl)-5-oxo-4-(pyridin-4-ylmethyl...) Show SMILES CN(C)c1ccc(cc1)C(=O)OCC1(CO)C\C(=C/c2ccncc2)C(=O)O1 Show InChI InChI=1S/C21H22N2O5/c1-23(2)18-5-3-16(4-6-18)19(25)27-14-21(13-24)12-17(20(26)28-21)11-15-7-9-22-10-8-15/h3-11,24H,12-14H2,1-2H3/b17-11+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cells				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50244446 ((E)-(2-(hydroxymethyl)-5-oxo-4-(pyridin-4-ylmethyl...) Show SMILES COc1ccc(cc1)C(=O)OCC1(CO)C\C(=C/c2ccncc2)C(=O)O1 Show InChI InChI=1S/C20H19NO6/c1-25-17-4-2-15(3-5-17)18(23)26-13-20(12-22)11-16(19(24)27-20)10-14-6-8-21-9-7-14/h2-10,22H,11-13H2,1H3/b16-10+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cells				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50244474 ((E)-(2-(hydroxymethyl)-5-oxo-4-(pyridin-3-ylmethyl...) Show SMILES CN(C)c1ccc(cc1)C(=O)OCC1(CO)C\C(=C/c2cccnc2)C(=O)O1 Show InChI InChI=1S/C21H22N2O5/c1-23(2)18-7-5-16(6-8-18)19(25)27-14-21(13-24)11-17(20(26)28-21)10-15-4-3-9-22-12-15/h3-10,12,24H,11,13-14H2,1-2H3/b17-10+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cells				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50244981 ((E)-(2-(hydroxymethyl)-5-oxo-4-(pyridin-3-ylmethyl...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2cccnc2)C(=O)O1 Show InChI InChI=1S/C20H27NO5/c1-3-6-16(7-4-2)18(23)25-14-20(13-22)11-17(19(24)26-20)10-15-8-5-9-21-12-15/h5,8-10,12,16,22H,3-4,6-7,11,13-14H2,1-2H3/b17-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from human recombinant PKCalpha expressed in Escherichia coli BL21-21-Gold (DE3)				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50245021 ((Z)-(2-(hydroxymethyl)-5-oxo-4-(quinolin-2-ylmethy...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C\c2ccc3ccccc3n2)C(=O)O1 Show InChI InChI=1S/C24H29NO5/c1-3-7-18(8-4-2)22(27)29-16-24(15-26)14-19(23(28)30-24)13-20-12-11-17-9-5-6-10-21(17)25-20/h5-6,9-13,18,26H,3-4,7-8,14-16H2,1-2H3/b19-13-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from human recombinant PKCalpha expressed in Escherichia coli BL21-21-Gold (DE3)				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50244977 ((E)-(2-(hydroxymethyl)-5-oxo-4-(pyridin-3-ylmethyl...) Show SMILES COc1ccc(cc1)C(=O)OCC1(CO)C\C(=C/c2cccnc2)C(=O)O1 Show InChI InChI=1S/C20H19NO6/c1-25-17-6-4-15(5-7-17)18(23)26-13-20(12-22)10-16(19(24)27-20)9-14-3-2-8-21-11-14/h2-9,11,22H,10,12-13H2,1H3/b16-9+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	81	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cells				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50244980 ((Z)-(2-(hydroxymethyl)-5-oxo-4-(pyridin-2-ylmethyl...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C\c2ccccn2)C(=O)O1 Show InChI InChI=1S/C20H27NO5/c1-3-7-15(8-4-2)18(23)25-14-20(13-22)12-16(19(24)26-20)11-17-9-5-6-10-21-17/h5-6,9-11,15,22H,3-4,7-8,12-14H2,1-2H3/b16-11-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	83	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cells				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50244979 ((E)-(2-(hydroxymethyl)-5-oxo-4-(pyridin-2-ylmethyl...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2ccccn2)C(=O)O1 Show InChI InChI=1S/C20H27NO5/c1-3-7-15(8-4-2)18(23)25-14-20(13-22)12-16(19(24)26-20)11-17-9-5-6-10-21-17/h5-6,9-11,15,22H,3-4,7-8,12-14H2,1-2H3/b16-11+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	86	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from human recombinant PKCalpha expressed in Escherichia coli BL21-21-Gold (DE3)				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50244448 ((E)-(2-(hydroxymethyl)-5-oxo-4-(quinolin-2-ylmethy...) Show SMILES COc1ccc(cc1)C(=O)OCC1(CO)C\C(=C/c2ccc3ccccc3n2)C(=O)O1 Show InChI InChI=1S/C24H21NO6/c1-29-20-10-7-17(8-11-20)22(27)30-15-24(14-26)13-18(23(28)31-24)12-19-9-6-16-4-2-3-5-21(16)25-19/h2-12,26H,13-15H2,1H3/b18-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	132	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from human recombinant PKCalpha expressed in Escherichia coli BL21-21-Gold (DE3)				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50244452 ((4-(4-nitrobenzylidene)-2-(hydroxymethyl)-5-oxo-te...) Show SMILES COc1ccc(cc1)C(=O)OCC1(CO)C\C(=C/c2ccc(cc2)[N+]([O-])=O)C(=O)O1 Show InChI InChI=1S/C21H19NO8/c1-28-18-8-4-15(5-9-18)19(24)29-13-21(12-23)11-16(20(25)30-21)10-14-2-6-17(7-3-14)22(26)27/h2-10,23H,11-13H2,1H3/b16-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	136	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from human recombinant PKCalpha expressed in Escherichia coli BL21-21-Gold (DE3)				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50244928 ((E)-(2-(hydroxymethyl)-5-oxo-4-(quinolin-3-ylmethy...) Show SMILES CN(C)c1ccc(cc1)C(=O)OCC1(CO)C\C(=C/c2cnc3ccccc3c2)C(=O)O1 Show InChI InChI=1S/C25H24N2O5/c1-27(2)21-9-7-18(8-10-21)23(29)31-16-25(15-28)13-20(24(30)32-25)12-17-11-19-5-3-4-6-22(19)26-14-17/h3-12,14,28H,13,15-16H2,1-2H3/b20-12+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	137	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cells				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50244479 ((E)-(2-(hydroxymethyl)-5-oxo-4-(quinolin-3-ylmethy...) Show SMILES COc1ccc(cc1)C(=O)OCC1(CO)C\C(=C/c2cnc3ccccc3c2)C(=O)O1 Show InChI InChI=1S/C24H21NO6/c1-29-20-8-6-17(7-9-20)22(27)30-15-24(14-26)12-19(23(28)31-24)11-16-10-18-4-2-3-5-21(18)25-13-16/h2-11,13,26H,12,14-15H2,1H3/b19-11+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	144	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from human recombinant PKCalpha expressed in Escherichia coli BL21-21-Gold (DE3)				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50244926 ((E)-(2-(hydroxymethyl)-5-oxo-4-(quinolin-2-ylmethy...) Show SMILES CN(C)c1ccc(cc1)C(=O)OCC1(CO)C\C(=C/c2ccc3ccccc3n2)C(=O)O1 Show InChI InChI=1S/C25H24N2O5/c1-27(2)21-11-8-18(9-12-21)23(29)31-16-25(15-28)14-19(24(30)32-25)13-20-10-7-17-5-3-4-6-22(17)26-20/h3-13,28H,14-16H2,1-2H3/b19-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from human recombinant PKCalpha expressed in Escherichia coli BL21-21-Gold (DE3)				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50244974 ((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...) Show SMILES CN(C)c1ccc(cc1)C(=O)OCC1(CO)C\C(=C/c2cn(C)c3ccccc23)C(=O)O1 Show InChI InChI=1S/C25H26N2O5/c1-26(2)20-10-8-17(9-11-20)23(29)31-16-25(15-28)13-18(24(30)32-25)12-19-14-27(3)22-7-5-4-6-21(19)22/h4-12,14,28H,13,15-16H2,1-3H3/b18-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	174	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from human recombinant PKCalpha expressed in Escherichia coli BL21-21-Gold (DE3)				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50245023 ((Z)-(2-(hydroxymethyl)-5-oxo-4-(quinolin-3-ylmethy...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C\c2cnc3ccccc3c2)C(=O)O1 Show InChI InChI=1S/C24H29NO5/c1-3-7-18(8-4-2)22(27)29-16-24(15-26)13-20(23(28)30-24)12-17-11-19-9-5-6-10-21(19)25-14-17/h5-6,9-12,14,18,26H,3-4,7-8,13,15-16H2,1-2H3/b20-12-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	177	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from human recombinant PKCalpha expressed in Escherichia coli BL21-21-Gold (DE3)				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50244481 ((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...) Show SMILES COc1ccc(cc1)C(=O)OCC1(CO)C\C(=C/c2cn(C)c3ccccc23)C(=O)O1 Show InChI InChI=1S/C24H23NO6/c1-25-13-18(20-5-3-4-6-21(20)25)11-17-12-24(14-26,31-23(17)28)15-30-22(27)16-7-9-19(29-2)10-8-16/h3-11,13,26H,12,14-15H2,1-2H3/b17-11+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	212	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from human recombinant PKCalpha expressed in Escherichia coli BL21-21-Gold (DE3)				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50244482 ((4-(4-nitrobenzylidene)-2-(hydroxymethyl)-5-oxo-te...) Show SMILES CN(C)c1ccc(cc1)C(=O)OCC1(CO)C\C(=C/c2ccc(cc2)[N+]([O-])=O)C(=O)O1 Show InChI InChI=1S/C22H22N2O7/c1-23(2)18-9-5-16(6-10-18)20(26)30-14-22(13-25)12-17(21(27)31-22)11-15-3-7-19(8-4-15)24(28)29/h3-11,25H,12-14H2,1-2H3/b17-11+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	343	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from human recombinant PKCalpha expressed in Escherichia coli BL21-21-Gold (DE3)				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50244983 ((E)-(2-(hydroxymethyl)-5-oxo-4-(pyridin-4-ylmethyl...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2ccncc2)C(=O)O1 Show InChI InChI=1S/C20H27NO5/c1-3-5-16(6-4-2)18(23)25-14-20(13-22)12-17(19(24)26-20)11-15-7-9-21-10-8-15/h7-11,16,22H,3-6,12-14H2,1-2H3/b17-11+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	627	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from human recombinant PKCalpha expressed in Escherichia coli BL21-21-Gold (DE3)				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50244982 ((Z)-(2-(hydroxymethyl)-5-oxo-4-(pyridin-3-ylmethyl...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C\c2cccnc2)C(=O)O1 Show InChI InChI=1S/C20H27NO5/c1-3-6-16(7-4-2)18(23)25-14-20(13-22)11-17(19(24)26-20)10-15-8-5-9-21-12-15/h5,8-10,12,16,22H,3-4,6-7,11,13-14H2,1-2H3/b17-10-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cells				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50244928 ((E)-(2-(hydroxymethyl)-5-oxo-4-(quinolin-3-ylmethy...) Show SMILES CN(C)c1ccc(cc1)C(=O)OCC1(CO)C\C(=C/c2cnc3ccccc3c2)C(=O)O1 Show InChI InChI=1S/C25H24N2O5/c1-27(2)21-9-7-18(8-10-21)23(29)31-16-25(15-28)13-20(24(30)32-25)12-17-11-19-5-3-4-6-22(19)26-14-17/h3-12,14,28H,13,15-16H2,1-2H3/b20-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	755	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from human recombinant PKCalpha expressed in Escherichia coli BL21-21-Gold (DE3)				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50244474 ((E)-(2-(hydroxymethyl)-5-oxo-4-(pyridin-3-ylmethyl...) Show SMILES CN(C)c1ccc(cc1)C(=O)OCC1(CO)C\C(=C/c2cccnc2)C(=O)O1 Show InChI InChI=1S/C21H22N2O5/c1-23(2)18-7-5-16(6-8-18)19(25)27-14-21(13-24)11-17(20(26)28-21)10-15-4-3-9-22-12-15/h3-10,12,24H,11,13-14H2,1-2H3/b17-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	790	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from human recombinant PKCalpha expressed in Escherichia coli BL21-21-Gold (DE3)				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50244977 ((E)-(2-(hydroxymethyl)-5-oxo-4-(pyridin-3-ylmethyl...) Show SMILES COc1ccc(cc1)C(=O)OCC1(CO)C\C(=C/c2cccnc2)C(=O)O1 Show InChI InChI=1S/C20H19NO6/c1-25-17-6-4-15(5-7-17)18(23)26-13-20(12-22)10-16(19(24)27-20)9-14-3-2-8-21-11-14/h2-9,11,22H,10,12-13H2,1H3/b16-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	810	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from human recombinant PKCalpha expressed in Escherichia coli BL21-21-Gold (DE3)				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50245019 ((Z)-(2-(hydroxymethyl)-5-oxo-4-(pyridin-4-ylmethyl...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C\c2ccncc2)C(=O)O1 Show InChI InChI=1S/C20H27NO5/c1-3-5-16(6-4-2)18(23)25-14-20(13-22)12-17(19(24)26-20)11-15-7-9-21-10-8-15/h7-11,16,22H,3-6,12-14H2,1-2H3/b17-11-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	870	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from human recombinant PKCalpha expressed in Escherichia coli BL21-21-Gold (DE3)				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Ras guanyl-releasing protein 3 (Homo sapiens (Human))	BDBM50244480 ((Z)-(2-(hydroxymethyl)-5-oxo-4-(quinolin-3-ylmethy...) Show SMILES COc1ccc(cc1)C(=O)OCC1(CO)C\C(=C\c2cnc3ccccc3c2)C(=O)O1 Show InChI InChI=1S/C24H21NO6/c1-29-20-8-6-17(7-9-20)22(27)30-15-24(14-26)12-19(23(28)31-24)11-16-10-18-4-2-3-5-21(18)25-13-16/h2-11,13,26H,12,14-15H2,1H3/b19-11-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	907	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cells				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50244473 ((E)-(2-(hydroxymethyl)-5-oxo-4-(pyridin-2-ylmethyl...) Show SMILES CN(C)c1ccc(cc1)C(=O)OCC1(CO)C\C(=C/c2ccccn2)C(=O)O1 Show InChI InChI=1S/C21H22N2O5/c1-23(2)18-8-6-15(7-9-18)19(25)27-14-21(13-24)12-16(20(26)28-21)11-17-5-3-4-10-22-17/h3-11,24H,12-14H2,1-2H3/b16-11+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from human recombinant PKCalpha expressed in Escherichia coli BL21-21-Gold (DE3)				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair

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