Compile Data Set for Download or QSAR

Found 127 hits Enz. Inhib. hit(s) with all data for entry = 50032526   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330507 (5-(4-Methylpiperazin-1-yl)-3-(m-tolylsulfonyl)-1H-...) Show SMILES CN1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc(C)c1 Show InChI InChI=1S/C19H22N4O2S/c1-14-4-3-5-16(12-14)26(24,25)19-17-13-15(6-7-18(17)20-21-19)23-10-8-22(2)9-11-23/h3-7,12-13H,8-11H2,1-2H3,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330538 (3-(3-Chlorophenylsulfonyl)-5-(4-methylpiperazin-1-...) Show SMILES CN1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C18H19ClN4O2S/c1-22-7-9-23(10-8-22)14-5-6-17-16(12-14)18(21-20-17)26(24,25)15-4-2-3-13(19)11-15/h2-6,11-12H,7-10H2,1H3,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330512 (3-(Naphthalen-1-ylsulfonyl)-5-(piperazin-1-yl)-1H-...) Show SMILES O=S(=O)(c1n[nH]c2ccc(cc12)N1CCNCC1)c1cccc2ccccc12 Show InChI InChI=1S/C21H20N4O2S/c26-28(27,20-7-3-5-15-4-1-2-6-17(15)20)21-18-14-16(8-9-19(18)23-24-21)25-12-10-22-11-13-25/h1-9,14,22H,10-13H2,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330505 (3-(3-Methoxyphenylsulfonyl)-5-(4-methylpiperazin-1...) Show SMILES COc1cccc(c1)S(=O)(=O)c1n[nH]c2ccc(cc12)N1CCN(C)CC1 Show InChI InChI=1S/C19H22N4O3S/c1-22-8-10-23(11-9-22)14-6-7-18-17(12-14)19(21-20-18)27(24,25)16-5-3-4-15(13-16)26-2/h3-7,12-13H,8-11H2,1-2H3,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330523 (1-isobutyl-5-(4-methylpiperazin-1-yl)-3-(naphthale...) Show SMILES CC(C)Cn1nc(c2cc(ccc12)N1CCN(C)CC1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C26H30N4O2S/c1-19(2)18-30-24-12-11-21(29-15-13-28(3)14-16-29)17-23(24)26(27-30)33(31,32)25-10-6-8-20-7-4-5-9-22(20)25/h4-12,17,19H,13-16,18H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330516 (1-methyl-3-(naphthalen-1-ylsulfonyl)-5-(piperazin-...) Show SMILES Cn1nc(c2cc(ccc12)N1CCNCC1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C22H22N4O2S/c1-25-20-10-9-17(26-13-11-23-12-14-26)15-19(20)22(24-25)29(27,28)21-8-4-6-16-5-2-3-7-18(16)21/h2-10,15,23H,11-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330511 (5-(4-Methylpiperazin-1-yl)-3-(1-naphthalenesulfony...) Show SMILES CN1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C22H22N4O2S/c1-25-11-13-26(14-12-25)17-9-10-20-19(15-17)22(24-23-20)29(27,28)21-8-4-6-16-5-2-3-7-18(16)21/h2-10,15H,11-14H2,1H3,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330535 (3-(3-Fluorophenylsulfonyl)-5-(4-methylpiperazin-1-...) Show SMILES CN1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc(F)c1 Show InChI InChI=1S/C18H19FN4O2S/c1-22-7-9-23(10-8-22)14-5-6-17-16(12-14)18(21-20-17)26(24,25)15-4-2-3-13(19)11-15/h2-6,11-12H,7-10H2,1H3,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330515 (1-methyl-5-(4-methylpiperazin-1-yl)-3-(naphthalen-...) Show SMILES CN1CCN(CC1)c1ccc2n(C)nc(c2c1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C23H24N4O2S/c1-25-12-14-27(15-13-25)18-10-11-21-20(16-18)23(24-26(21)2)30(28,29)22-9-5-7-17-6-3-4-8-19(17)22/h3-11,16H,12-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330517 (1-ethyl-5-(4-methylpiperazin-1-yl)-3-(naphthalen-1...) Show SMILES CCn1nc(c2cc(ccc12)N1CCN(C)CC1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C24H26N4O2S/c1-3-28-22-12-11-19(27-15-13-26(2)14-16-27)17-21(22)24(25-28)31(29,30)23-10-6-8-18-7-4-5-9-20(18)23/h4-12,17H,3,13-16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330521 (1-isopropyl-5-(4-methylpiperazin-1-yl)-3-(naphthal...) Show SMILES CC(C)n1nc(c2cc(ccc12)N1CCN(C)CC1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C25H28N4O2S/c1-18(2)29-23-12-11-20(28-15-13-27(3)14-16-28)17-22(23)25(26-29)32(30,31)24-10-6-8-19-7-4-5-9-21(19)24/h4-12,17-18H,13-16H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330519 (5-(4-methylpiperazin-1-yl)-3-(naphthalen-1-ylsulfo...) Show SMILES CCCn1nc(c2cc(ccc12)N1CCN(C)CC1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C25H28N4O2S/c1-3-13-29-23-12-11-20(28-16-14-27(2)15-17-28)18-22(23)25(26-29)32(30,31)24-10-6-8-19-7-4-5-9-21(19)24/h4-12,18H,3,13-17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330518 (1-ethyl-3-(naphthalen-1-ylsulfonyl)-5-(piperazin-1...) Show SMILES CCn1nc(c2cc(ccc12)N1CCNCC1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C23H24N4O2S/c1-2-27-21-11-10-18(26-14-12-24-13-15-26)16-20(21)23(25-27)30(28,29)22-9-5-7-17-6-3-4-8-19(17)22/h3-11,16,24H,2,12-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330533 (5-(4-methylpiperazin-1-yl)-3-(phenylsulfonyl)-1H-i...) Show SMILES CN1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C18H20N4O2S/c1-21-9-11-22(12-10-21)14-7-8-17-16(13-14)18(20-19-17)25(23,24)15-5-3-2-4-6-15/h2-8,13H,9-12H2,1H3,(H,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330525 (1-benzyl-5-(4-methylpiperazin-1-yl)-3-(naphthalen-...) Show SMILES CN1CCN(CC1)c1ccc2n(Cc3ccccc3)nc(c2c1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C29H28N4O2S/c1-31-16-18-32(19-17-31)24-14-15-27-26(20-24)29(30-33(27)21-22-8-3-2-4-9-22)36(34,35)28-13-7-11-23-10-5-6-12-25(23)28/h2-15,20H,16-19,21H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330520 (3-(naphthalen-1-ylsulfonyl)-5-(piperazin-1-yl)-1-p...) Show SMILES CCCn1nc(c2cc(ccc12)N1CCNCC1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C24H26N4O2S/c1-2-14-28-22-11-10-19(27-15-12-25-13-16-27)17-21(22)24(26-28)31(29,30)23-9-5-7-18-6-3-4-8-20(18)23/h3-11,17,25H,2,12-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330510 (3-(2,6-Dichlorophenylsulfonyl)-5-(4-methylpiperazi...) Show SMILES CN1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1c(Cl)cccc1Cl Show InChI InChI=1S/C18H18Cl2N4O2S/c1-23-7-9-24(10-8-23)12-5-6-16-13(11-12)18(22-21-16)27(25,26)17-14(19)3-2-4-15(17)20/h2-6,11H,7-10H2,1H3,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330514 (1-ethyl-3-(phenylsulfonyl)-5-(piperazin-1-yl)-1H-i...) Show SMILES CCn1nc(c2cc(ccc12)N1CCNCC1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C19H22N4O2S/c1-2-23-18-9-8-15(22-12-10-20-11-13-22)14-17(18)19(21-23)26(24,25)16-6-4-3-5-7-16/h3-9,14,20H,2,10-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330522 (1-isopropyl-3-(naphthalen-1-ylsulfonyl)-5-(piperaz...) Show SMILES CC(C)n1nc(c2cc(ccc12)N1CCNCC1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C24H26N4O2S/c1-17(2)28-22-11-10-19(27-14-12-25-13-15-27)16-21(22)24(26-28)31(29,30)23-9-5-7-18-6-3-4-8-20(18)23/h3-11,16-17,25H,12-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330527 (1-methyl-3-(phenylsulfonyl)-5-(piperazin-1-yl)-1H-...) Show SMILES Cn1nc(c2cc(ccc12)N1CCNCC1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C18H20N4O2S/c1-21-17-8-7-14(22-11-9-19-10-12-22)13-16(17)18(20-21)25(23,24)15-5-3-2-4-6-15/h2-8,13,19H,9-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330537 (3-(2-Chlorophenylsulfonyl)-5-(4-methylpiperazin-1-...) Show SMILES CN1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1ccccc1Cl Show InChI InChI=1S/C18H19ClN4O2S/c1-22-8-10-23(11-9-22)13-6-7-16-14(12-13)18(21-20-16)26(24,25)17-5-3-2-4-15(17)19/h2-7,12H,8-11H2,1H3,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330524 (1-isobutyl-3-(naphthalen-1-ylsulfonyl)-5-(piperazi...) Show SMILES CC(C)Cn1nc(c2cc(ccc12)N1CCNCC1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C25H28N4O2S/c1-18(2)17-29-23-11-10-20(28-14-12-26-13-15-28)16-22(23)25(27-29)32(30,31)24-9-5-7-19-6-3-4-8-21(19)24/h3-11,16,18,26H,12-15,17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330513 (7-(4-methylpiperazin-1-yl)-3-(naphthalen-1-ylsulfo...) Show SMILES CN1CCN(CC1)c1cccc2c(n[nH]c12)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C22H22N4O2S/c1-25-12-14-26(15-13-25)19-10-5-9-18-21(19)23-24-22(18)29(27,28)20-11-4-7-16-6-2-3-8-17(16)20/h2-11H,12-15H2,1H3,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330508 (5-(4-Methylpiperazin-1-yl)-3-tosyl-1H-indazole | C...) Show SMILES CN1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1ccc(C)cc1 Show InChI InChI=1S/C19H22N4O2S/c1-14-3-6-16(7-4-14)26(24,25)19-17-13-15(5-8-18(17)20-21-19)23-11-9-22(2)10-12-23/h3-8,13H,9-12H2,1-2H3,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330536 (3-(4-Fluorophenylsulfonyl)-5-(4-methylpiperazin-1-...) Show SMILES CN1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C18H19FN4O2S/c1-22-8-10-23(11-9-22)14-4-7-17-16(12-14)18(21-20-17)26(24,25)15-5-2-13(19)3-6-15/h2-7,12H,8-11H2,1H3,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330534 (3-(2-fluorophenylsulfonyl)-5-(4-methylpiperazin-1-...) Show SMILES CN1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1ccccc1F Show InChI InChI=1S/C18H19FN4O2S/c1-22-8-10-23(11-9-22)13-6-7-16-14(12-13)18(21-20-16)26(24,25)17-5-3-2-4-15(17)19/h2-7,12H,8-11H2,1H3,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330526 (1-benzyl-3-(naphthalen-1-ylsulfonyl)-5-(piperazin-...) Show SMILES O=S(=O)(c1nn(Cc2ccccc2)c2ccc(cc12)N1CCNCC1)c1cccc2ccccc12 Show InChI InChI=1S/C28H26N4O2S/c33-35(34,27-12-6-10-22-9-4-5-11-24(22)27)28-25-19-23(31-17-15-29-16-18-31)13-14-26(25)32(30-28)20-21-7-2-1-3-8-21/h1-14,19,29H,15-18,20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330509 (5-(4-Methylpiperazin-1-yl)-3-(thiophen-2-ylsulfony...) Show SMILES CN1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccs1 Show InChI InChI=1S/C16H18N4O2S2/c1-19-6-8-20(9-7-19)12-4-5-14-13(11-12)16(18-17-14)24(21,22)15-3-2-10-23-15/h2-5,10-11H,6-9H2,1H3,(H,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	7.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330539 (3-(4-Chlorophenylsulfonyl)-5-(4-methylpiperazin-1-...) Show SMILES CN1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C18H19ClN4O2S/c1-22-8-10-23(11-9-22)14-4-7-17-16(12-14)18(21-20-17)26(24,25)15-5-2-13(19)3-6-15/h2-7,12H,8-11H2,1H3,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330540 (3-(3-fluorophenylsulfonyl)-6-(piperazin-1-yl)-1H-i...) Show SMILES Fc1cccc(c1)S(=O)(=O)c1n[nH]c2cc(ccc12)N1CCNCC1 Show InChI InChI=1S/C17H17FN4O2S/c18-12-2-1-3-14(10-12)25(23,24)17-15-5-4-13(11-16(15)20-21-17)22-8-6-19-7-9-22/h1-5,10-11,19H,6-9H2,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330506 (3-(4-Methoxyphenylsulfonyl)-5-(4-methylpiperazin-1...) Show SMILES COc1ccc(cc1)S(=O)(=O)c1n[nH]c2ccc(cc12)N1CCN(C)CC1 Show InChI InChI=1S/C19H22N4O3S/c1-22-9-11-23(12-10-22)14-3-8-18-17(13-14)19(21-20-18)27(24,25)16-6-4-15(26-2)5-7-16/h3-8,13H,9-12H2,1-2H3,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330545 (3-(naphthalen-1-ylsulfonyl)-6-(piperazin-1-yl)-1H-...) Show SMILES O=S(=O)(c1n[nH]c2cc(ccc12)N1CCNCC1)c1cccc2ccccc12 Show InChI InChI=1S/C21H20N4O2S/c26-28(27,20-7-3-5-15-4-1-2-6-17(15)20)21-18-9-8-16(14-19(18)23-24-21)25-12-10-22-11-13-25/h1-9,14,22H,10-13H2,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330542 (6-(piperazin-1-yl)-3-tosyl-1H-indazole | CHEMBL127...) Show SMILES Cc1ccc(cc1)S(=O)(=O)c1n[nH]c2cc(ccc12)N1CCNCC1 Show InChI InChI=1S/C18H20N4O2S/c1-13-2-5-15(6-3-13)25(23,24)18-16-7-4-14(12-17(16)20-21-18)22-10-8-19-9-11-22/h2-7,12,19H,8-11H2,1H3,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330532 (3-(naphthalen-1-ylsulfonyl)-4-(piperazin-1-yl)-1H-...) Show SMILES O=S(=O)(c1n[nH]c2cccc(N3CCNCC3)c12)c1cccc2ccccc12 Show InChI InChI=1S/C21H20N4O2S/c26-28(27,19-10-3-6-15-5-1-2-7-16(15)19)21-20-17(23-24-21)8-4-9-18(20)25-13-11-22-12-14-25/h1-10,22H,11-14H2,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50330516 (1-methyl-3-(naphthalen-1-ylsulfonyl)-5-(piperazin-...) Show SMILES Cn1nc(c2cc(ccc12)N1CCNCC1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C22H22N4O2S/c1-25-20-10-9-17(26-13-11-23-12-14-26)15-19(20)22(24-25)29(27,28)21-8-4-6-16-5-2-3-7-18(16)21/h2-10,15,23H,11-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	87	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT2B receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330531 (3-(4-methoxyphenylsulfonyl)-4-(piperazin-1-yl)-1H-...) Show SMILES COc1ccc(cc1)S(=O)(=O)c1n[nH]c2cccc(N3CCNCC3)c12 Show InChI InChI=1S/C18H20N4O3S/c1-25-13-5-7-14(8-6-13)26(23,24)18-17-15(20-21-18)3-2-4-16(17)22-11-9-19-10-12-22/h2-8,19H,9-12H2,1H3,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50330522 (1-isopropyl-3-(naphthalen-1-ylsulfonyl)-5-(piperaz...) Show SMILES CC(C)n1nc(c2cc(ccc12)N1CCNCC1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C24H26N4O2S/c1-17(2)28-22-11-10-19(27-14-12-25-13-15-27)16-21(22)24(26-28)31(29,30)23-9-5-7-18-6-3-4-8-20(18)23/h3-11,16-17,25H,12-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	96	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT2B receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330541 (3-(4-chlorophenylsulfonyl)-6-(piperazin-1-yl)-1H-i...) Show SMILES Clc1ccc(cc1)S(=O)(=O)c1n[nH]c2cc(ccc12)N1CCNCC1 Show InChI InChI=1S/C17H17ClN4O2S/c18-12-1-4-14(5-2-12)25(23,24)17-15-6-3-13(11-16(15)20-21-17)22-9-7-19-8-10-22/h1-6,11,19H,7-10H2,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330543 (3-(4-methoxyphenylsulfonyl)-6-(piperazin-1-yl)-1H-...) Show SMILES COc1ccc(cc1)S(=O)(=O)c1n[nH]c2cc(ccc12)N1CCNCC1 Show InChI InChI=1S/C18H20N4O3S/c1-25-14-3-5-15(6-4-14)26(23,24)18-16-7-2-13(12-17(16)20-21-18)22-10-8-19-9-11-22/h2-7,12,19H,8-11H2,1H3,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	124	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330529 (3-(4-chlorophenylsulfonyl)-4-(piperazin-1-yl)-1H-i...) Show SMILES Clc1ccc(cc1)S(=O)(=O)c1n[nH]c2cccc(N3CCNCC3)c12 Show InChI InChI=1S/C17H17ClN4O2S/c18-12-4-6-13(7-5-12)25(23,24)17-16-14(20-21-17)2-1-3-15(16)22-10-8-19-9-11-22/h1-7,19H,8-11H2,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	125	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330530 (4-(piperazin-1-yl)-3-tosyl-1H-indazole | CHEMBL127...) Show SMILES Cc1ccc(cc1)S(=O)(=O)c1n[nH]c2cccc(N3CCNCC3)c12 Show InChI InChI=1S/C18H20N4O2S/c1-13-5-7-14(8-6-13)25(23,24)18-17-15(20-21-18)3-2-4-16(17)22-11-9-19-10-12-22/h2-8,19H,9-12H2,1H3,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	134	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330528 (3-(3-fluorophenylsulfonyl)-4-(piperazin-1-yl)-1H-i...) Show SMILES Fc1cccc(c1)S(=O)(=O)c1n[nH]c2cccc(N3CCNCC3)c12 Show InChI InChI=1S/C17H17FN4O2S/c18-12-3-1-4-13(11-12)25(23,24)17-16-14(20-21-17)5-2-6-15(16)22-9-7-19-8-10-22/h1-6,11,19H,7-10H2,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	134	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50330526 (1-benzyl-3-(naphthalen-1-ylsulfonyl)-5-(piperazin-...) Show SMILES O=S(=O)(c1nn(Cc2ccccc2)c2ccc(cc12)N1CCNCC1)c1cccc2ccccc12 Show InChI InChI=1S/C28H26N4O2S/c33-35(34,27-12-6-10-22-9-4-5-11-24(22)27)28-25-19-23(31-17-15-29-16-18-31)13-14-26(25)32(30-28)20-21-7-2-1-3-8-21/h1-14,19,29H,15-18,20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	141	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT2B receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50330544 (6-(piperazin-1-yl)-3-(4-(trifluoromethyl)phenylsul...) Show SMILES FC(F)(F)c1ccc(cc1)S(=O)(=O)c1n[nH]c2cc(ccc12)N1CCNCC1 Show InChI InChI=1S/C18H17F3N4O2S/c19-18(20,21)12-1-4-14(5-2-12)28(26,27)17-15-6-3-13(11-16(15)23-24-17)25-9-7-22-8-10-25/h1-6,11,22H,7-10H2,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	207	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50330512 (3-(Naphthalen-1-ylsulfonyl)-5-(piperazin-1-yl)-1H-...) Show SMILES O=S(=O)(c1n[nH]c2ccc(cc12)N1CCNCC1)c1cccc2ccccc12 Show InChI InChI=1S/C21H20N4O2S/c26-28(27,20-7-3-5-15-4-1-2-6-17(15)20)21-18-14-16(8-9-19(18)23-24-21)25-12-10-22-11-13-25/h1-9,14,22H,10-13H2,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	236	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT2B receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50330524 (1-isobutyl-3-(naphthalen-1-ylsulfonyl)-5-(piperazi...) Show SMILES CC(C)Cn1nc(c2cc(ccc12)N1CCNCC1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C25H28N4O2S/c1-18(2)17-29-23-11-10-20(28-14-12-26-13-15-28)16-22(23)25(27-29)32(30,31)24-9-5-7-19-6-3-4-8-21(19)24/h3-11,16,18,26H,12-15,17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	281	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT2B receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50330511 (5-(4-Methylpiperazin-1-yl)-3-(1-naphthalenesulfony...) Show SMILES CN1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C22H22N4O2S/c1-25-11-13-26(14-12-25)17-9-10-20-19(15-17)22(24-23-20)29(27,28)21-8-4-6-16-5-2-3-7-18(16)21/h2-10,15H,11-14H2,1H3,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	334	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned dopamine D2 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50330533 (5-(4-methylpiperazin-1-yl)-3-(phenylsulfonyl)-1H-i...) Show SMILES CN1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C18H20N4O2S/c1-21-9-11-22(12-10-21)14-7-8-17-16(13-14)18(20-19-17)25(23,24)15-5-3-2-4-6-15/h2-8,13H,9-12H2,1H3,(H,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	355	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned dopamine D2 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50330512 (3-(Naphthalen-1-ylsulfonyl)-5-(piperazin-1-yl)-1H-...) Show SMILES O=S(=O)(c1n[nH]c2ccc(cc12)N1CCNCC1)c1cccc2ccccc12 Show InChI InChI=1S/C21H20N4O2S/c26-28(27,20-7-3-5-15-4-1-2-6-17(15)20)21-18-14-16(8-9-19(18)23-24-21)25-12-10-22-11-13-25/h1-9,14,22H,10-13H2,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	573	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT1A receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50330511 (5-(4-Methylpiperazin-1-yl)-3-(1-naphthalenesulfony...) Show SMILES CN1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C22H22N4O2S/c1-25-11-13-26(14-12-25)17-9-10-20-19(15-17)22(24-23-20)29(27,28)21-8-4-6-16-5-2-3-7-18(16)21/h2-10,15H,11-14H2,1H3,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	579	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT7 receptor expressed in human HeLa cells				J Med Chem 53: 7639-46 (2010) Article DOI: 10.1021/jm1007825 BindingDB Entry DOI: 10.7270/Q2GQ6XZ6
					More data for this Ligand-Target Pair

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