Compile Data Set for Download or QSAR

Found 35 hits Enz. Inhib. hit(s) with all data for entry = 50033517   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50346783 (CHEMBL1795446) Show SMILES CC(C)(O)[C@H]1Cc2cc3cc(oc3cc2O1)-c1ccc(O)cc1 |r| Show InChI InChI=1S/C19H18O4/c1-19(2,21)18-9-13-7-12-8-15(11-3-5-14(20)6-4-11)22-16(12)10-17(13)23-18/h3-8,10,18,20-21H,9H2,1-2H3/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50346783 (CHEMBL1795446) Show SMILES CC(C)(O)[C@H]1Cc2cc3cc(oc3cc2O1)-c1ccc(O)cc1 |r| Show InChI InChI=1S/C19H18O4/c1-19(2,21)18-9-13-7-12-8-15(11-3-5-14(20)6-4-11)22-16(12)10-17(13)23-18/h3-8,10,18,20-21H,9H2,1-2H3/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50346796 (CHEMBL1795432) Show SMILES CC(C)(O)[C@H]1Cc2cc3cc(oc3cc2O1)-c1cc(O)cc(O)c1 |r| Show InChI InChI=1S/C19H18O5/c1-19(2,22)18-7-11-3-10-6-15(23-16(10)9-17(11)24-18)12-4-13(20)8-14(21)5-12/h3-6,8-9,18,20-22H,7H2,1-2H3/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.76	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50179013 (CHEMBL205924 | moracin O) Show SMILES CC(C)(O)C1Cc2cc3cc(oc3cc2O1)-c1cc(O)cc(O)c1 Show InChI InChI=1S/C19H18O5/c1-19(2,22)18-7-11-3-10-6-15(23-16(10)9-17(11)24-18)12-4-13(20)8-14(21)5-12/h3-6,8-9,18,20-22H,7H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.76	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50346790 (CHEMBL1795439) Show SMILES COc1cccc(c1)-c1cc2cc3CC(Oc3cc2o1)C(C)(C)O Show InChI InChI=1S/C20H20O4/c1-20(2,21)19-10-14-7-13-9-16(23-17(13)11-18(14)24-19)12-5-4-6-15(8-12)22-3/h4-9,11,19,21H,10H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50346795 (CHEMBL1795433) Show SMILES COc1cc(OC)cc(c1)-c1cc2cc3CC(Oc3cc2o1)C(C)(C)O Show InChI InChI=1S/C21H22O5/c1-21(2,22)20-9-13-5-12-8-17(25-18(12)11-19(13)26-20)14-6-15(23-3)10-16(7-14)24-4/h5-8,10-11,20,22H,9H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50179011 (CHEMBL380456 | Moracin P) Show SMILES CC1(C)Oc2cc3oc(cc3cc2CC1O)-c1cc(O)cc(O)c1 Show InChI InChI=1S/C19H18O5/c1-19(2)18(22)7-11-3-10-6-15(23-16(10)9-17(11)24-19)12-4-13(20)8-14(21)5-12/h3-6,8-9,18,20-22H,7H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10.7	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50346784 (CHEMBL1795445) Show SMILES Cn1cncc1-c1cc2cc3CC(Oc3cc2o1)C(C)(C)O Show InChI InChI=1S/C17H18N2O3/c1-17(2,20)16-6-11-4-10-5-15(12-8-18-9-19(12)3)21-13(10)7-14(11)22-16/h4-5,7-9,16,20H,6H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>30	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50346794 (CHEMBL1795434) Show SMILES CC(C)(O)C1Cc2cc3cc(oc3cc2O1)-c1cccc(O)c1 Show InChI InChI=1S/C19H18O4/c1-19(2,21)18-9-13-6-12-8-15(11-4-3-5-14(20)7-11)22-16(12)10-17(13)23-18/h3-8,10,18,20-21H,9H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50346793 (CHEMBL1795436) Show SMILES CCOC(=O)COc1ccc(cc1)-c1cc2cc3CC(Oc3cc2o1)C(C)(C)O Show InChI InChI=1S/C23H24O6/c1-4-26-22(24)13-27-17-7-5-14(6-8-17)18-10-15-9-16-11-21(23(2,3)25)29-20(16)12-19(15)28-18/h5-10,12,21,25H,4,11,13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50346788 (CHEMBL1795441) Show SMILES CC(C)(O)C1Cc2cc3cc(oc3cc2O1)-c1ccccc1 Show InChI InChI=1S/C19H18O3/c1-19(2,20)18-10-14-8-13-9-15(12-6-4-3-5-7-12)21-16(13)11-17(14)22-18/h3-9,11,18,20H,10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50346789 (CHEMBL1795440) Show SMILES COc1ccc(cc1)-c1cc2cc3CC(Oc3cc2o1)C(C)(C)O Show InChI InChI=1S/C20H20O4/c1-20(2,21)19-10-14-8-13-9-16(23-17(13)11-18(14)24-19)12-4-6-15(22-3)7-5-12/h4-9,11,19,21H,10H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50346787 (CHEMBL1795442) Show SMILES Cc1ccc(cc1)-c1cc2cc3CC(Oc3cc2o1)C(C)(C)O Show InChI InChI=1S/C20H20O3/c1-12-4-6-13(7-5-12)16-9-14-8-15-10-19(20(2,3)21)23-18(15)11-17(14)22-16/h4-9,11,19,21H,10H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50346786 (CHEMBL1795443) Show SMILES CC(C)(O)C1Cc2cc3cc(oc3cc2O1)-c1cc(F)cc(F)c1 Show InChI InChI=1S/C19H16F2O3/c1-19(2,22)18-7-11-3-10-6-15(23-16(10)9-17(11)24-18)12-4-13(20)8-14(21)5-12/h3-6,8-9,18,22H,7H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50346792 (CHEMBL1795437) Show SMILES CC(C)(O)C1Cc2cc3cc(oc3cc2O1)-c1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C26H24O4/c1-26(2,27)25-14-20-12-19-13-22(29-23(19)15-24(20)30-25)18-8-10-21(11-9-18)28-16-17-6-4-3-5-7-17/h3-13,15,25,27H,14,16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50346791 (CHEMBL1795438) Show SMILES COc1ccccc1-c1cc2cc3CC(Oc3cc2o1)C(C)(C)O Show InChI InChI=1S/C20H20O4/c1-20(2,21)19-10-13-8-12-9-18(23-16(12)11-17(13)24-19)14-6-4-5-7-15(14)22-3/h4-9,11,19,21H,10H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50346785 (CHEMBL1795444) Show SMILES CC(C)(O)C1Cc2cc3cc(oc3cc2O1)-c1ccncc1 Show InChI InChI=1S/C18H17NO3/c1-18(2,20)17-9-13-7-12-8-14(11-3-5-19-6-4-11)21-15(12)10-16(13)22-17/h3-8,10,17,20H,9H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50346774 (CHEMBL1795456) Show SMILES CC1(C)Oc2cc(OC(=O)c3cc(OCc4ccccc4)cc(OCc4ccccc4)c3)ccc2CC1O Show InChI InChI=1S/C32H30O6/c1-32(2)30(33)17-24-13-14-26(19-29(24)38-32)37-31(34)25-15-27(35-20-22-9-5-3-6-10-22)18-28(16-25)36-21-23-11-7-4-8-12-23/h3-16,18-19,30,33H,17,20-21H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50346771 (CHEMBL1795431) Show SMILES CC1(C)Oc2cc(OC(=O)c3cccc(OCc4ccccc4)c3)ccc2CC1O Show InChI InChI=1S/C25H24O5/c1-25(2)23(26)14-18-11-12-21(15-22(18)30-25)29-24(27)19-9-6-10-20(13-19)28-16-17-7-4-3-5-8-17/h3-13,15,23,26H,14,16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50346773 (CHEMBL1795455) Show SMILES CC1(C)Oc2cc(OC(=O)c3ccc(OCc4ccccc4)c(OCc4ccccc4)c3)ccc2CC1O Show InChI InChI=1S/C32H30O6/c1-32(2)30(33)18-24-13-15-26(19-28(24)38-32)37-31(34)25-14-16-27(35-20-22-9-5-3-6-10-22)29(17-25)36-21-23-11-7-4-8-12-23/h3-17,19,30,33H,18,20-21H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50179011 (CHEMBL380456 | Moracin P) Show SMILES CC1(C)Oc2cc3oc(cc3cc2CC1O)-c1cc(O)cc(O)c1 Show InChI InChI=1S/C19H18O5/c1-19(2)18(22)7-11-3-10-6-15(23-16(10)9-17(11)24-19)12-4-13(20)8-14(21)5-12/h3-6,8-9,18,20-22H,7H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50346772 (CHEMBL1795457) Show SMILES CC1(C)Oc2cc(OC(=O)c3ccc(OCc4ccccc4)cc3)ccc2CC1O Show InChI InChI=1S/C25H24O5/c1-25(2)23(26)14-19-10-13-21(15-22(19)30-25)29-24(27)18-8-11-20(12-9-18)28-16-17-6-4-3-5-7-17/h3-13,15,23,26H,14,16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50346770 (CHEMBL1795454) Show SMILES CC1(C)Oc2cc(OC(=O)c3ccc(Br)cc3)ccc2CC1O Show InChI InChI=1S/C18H17BrO4/c1-18(2)16(20)9-12-5-8-14(10-15(12)23-18)22-17(21)11-3-6-13(19)7-4-11/h3-8,10,16,20H,9H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.68E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50346769 (CHEMBL1795453) Show SMILES COc1cccc(c1)-c1ccc(cc1)C(=O)Oc1ccc2CC(O)C(C)(C)Oc2c1 Show InChI InChI=1S/C25H24O5/c1-25(2)23(26)14-19-11-12-21(15-22(19)30-25)29-24(27)17-9-7-16(8-10-17)18-5-4-6-20(13-18)28-3/h4-13,15,23,26H,14H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.72E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50346768 (CHEMBL1795452) Show SMILES CC1(C)Oc2cc(OC(=O)c3ccc(cc3)-c3cccc(c3)[N+]([O-])=O)ccc2CC1O Show InChI InChI=1S/C24H21NO6/c1-24(2)22(26)13-18-10-11-20(14-21(18)31-24)30-23(27)16-8-6-15(7-9-16)17-4-3-5-19(12-17)25(28)29/h3-12,14,22,26H,13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50346766 (CHEMBL1795451) Show SMILES CC1(C)Oc2cc(OC(=O)c3ccc(F)cc3F)ccc2CC1O Show InChI InChI=1S/C18H16F2O4/c1-18(2)16(21)7-10-3-5-12(9-15(10)24-18)23-17(22)13-6-4-11(19)8-14(13)20/h3-6,8-9,16,21H,7H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.76E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50346781 (CHEMBL1795448) Show SMILES CC(C)(O)C1Cc2ccc(OC(=O)c3cc(OCc4ccccc4)cc(OCc4ccccc4)c3)cc2O1 Show InChI InChI=1S/C32H30O6/c1-32(2,34)30-17-24-13-14-26(19-29(24)38-30)37-31(33)25-15-27(35-20-22-9-5-3-6-10-22)18-28(16-25)36-21-23-11-7-4-8-12-23/h3-16,18-19,30,34H,17,20-21H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.62E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50346782 (CHEMBL1795447) Show SMILES CC(C)(O)C1Cc2ccc(OC(=O)c3cc(O)cc(O)c3)cc2O1 Show InChI InChI=1S/C18H18O6/c1-18(2,22)16-7-10-3-4-14(9-15(10)24-16)23-17(21)11-5-12(19)8-13(20)6-11/h3-6,8-9,16,19-20,22H,7H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50346777 (CHEMBL1795427) Show SMILES CC1(C)Oc2cc(OC(=O)c3cc(O)cc(O)c3)ccc2CC1O Show InChI InChI=1S/C18H18O6/c1-18(2)16(21)7-10-3-4-14(9-15(10)24-18)23-17(22)11-5-12(19)8-13(20)6-11/h3-6,8-9,16,19-21H,7H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50346776 (CHEMBL1795428) Show SMILES CC1(C)Oc2cc(OC(=O)c3ccc(O)c(O)c3)ccc2CC1O Show InChI InChI=1S/C18H18O6/c1-18(2)16(21)8-10-3-5-12(9-15(10)24-18)23-17(22)11-4-6-13(19)14(20)7-11/h3-7,9,16,19-21H,8H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50346775 (CHEMBL1795429) Show SMILES CC1(C)Oc2cc(OC(=O)c3ccc(O)cc3)ccc2CC1O Show InChI InChI=1S/C18H18O5/c1-18(2)16(20)9-12-5-8-14(10-15(12)23-18)22-17(21)11-3-6-13(19)7-4-11/h3-8,10,16,19-20H,9H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50346767 (CHEMBL1795430) Show SMILES CC1(C)Oc2cc(OC(=O)c3cccc(c3)C#N)ccc2CC1O Show InChI InChI=1S/C19H17NO4/c1-19(2)17(21)9-13-6-7-15(10-16(13)24-19)23-18(22)14-5-3-4-12(8-14)11-20/h3-8,10,17,21H,9H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50346779 (CHEMBL1795450) Show SMILES COc1cccc(c1)-c1ccc(cc1)C(=O)Oc1ccc2CC(Oc2c1)C(C)(C)O Show InChI InChI=1S/C25H24O5/c1-25(2,27)23-14-19-11-12-21(15-22(19)30-23)29-24(26)17-9-7-16(8-10-17)18-5-4-6-20(13-18)28-3/h4-13,15,23,27H,14H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50346780 (CHEMBL1795449) Show SMILES CC(C)(O)C1Cc2ccc(OC(=O)c3ccc(Br)cc3)cc2O1 Show InChI InChI=1S/C18H17BrO4/c1-18(2,21)16-9-12-5-8-14(10-15(12)23-16)22-17(20)11-3-6-13(19)7-4-11/h3-8,10,16,21H,9H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50346778 (CHEMBL1795426) Show SMILES CC(C)(O)C1Cc2ccc(OC(=O)c3ccc(cc3)-c3cccc(c3)[N+]([O-])=O)cc2O1 Show InChI InChI=1S/C24H21NO6/c1-24(2,27)22-13-18-10-11-20(14-21(18)31-22)30-23(26)16-8-6-15(7-9-16)17-4-3-5-19(12-17)25(28)29/h3-12,14,22,27H,13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University-Seoul Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay				Eur J Med Chem 46: 2386-96 (2011) Article DOI: 10.1016/j.ejmech.2011.03.022 BindingDB Entry DOI: 10.7270/Q2WD40XF
					More data for this Ligand-Target Pair