Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50095997 (3',4',7-trihydroxyisoflavone | CHEMBL13486) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB PubMed | 38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yamanouchi Pharmaceutical Company Ltd. Curated by ChEMBL | Assay Description Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF) | J Med Chem 44: 540-7 (2001) BindingDB Entry DOI: 10.7270/Q2W66MGR | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50096004 (7-Hydroxy-3-[4-(2-oxo-2H-chromen-3-yl)-thiazol-2-y...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yamanouchi Pharmaceutical Company Ltd. Curated by ChEMBL | Assay Description Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF) | J Med Chem 44: 540-7 (2001) BindingDB Entry DOI: 10.7270/Q2W66MGR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50096003 (7-Hydroxy-3-phenyl-chromen-2-one | 7-hydroxy-3-phe...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yamanouchi Pharmaceutical Company Ltd. Curated by ChEMBL | Assay Description Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF) | J Med Chem 44: 540-7 (2001) BindingDB Entry DOI: 10.7270/Q2W66MGR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50096001 (7-Hydroxy-3-pyrazolo[1,5-a]pyridin-2-yl-chromen-2-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yamanouchi Pharmaceutical Company Ltd. Curated by ChEMBL | Assay Description Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF) | J Med Chem 44: 540-7 (2001) BindingDB Entry DOI: 10.7270/Q2W66MGR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50095993 (7-Hydroxy-2-oxo-2H-chromene-3-carbothioic acid ami...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | PubMed | 550 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yamanouchi Pharmaceutical Company Ltd. Curated by ChEMBL | Assay Description Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF) | J Med Chem 44: 540-7 (2001) BindingDB Entry DOI: 10.7270/Q2W66MGR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50096002 (3-(4-Benzo[1,3]dioxol-5-yl-thiazol-2-yl)-7-hydroxy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yamanouchi Pharmaceutical Company Ltd. Curated by ChEMBL | Assay Description Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF) | J Med Chem 44: 540-7 (2001) BindingDB Entry DOI: 10.7270/Q2W66MGR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50096007 (2-Oxo-2H-chromene-3-carboxylic acid 2-oxo-2-phenyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yamanouchi Pharmaceutical Company Ltd. Curated by ChEMBL | Assay Description Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF) | J Med Chem 44: 540-7 (2001) BindingDB Entry DOI: 10.7270/Q2W66MGR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50096006 (7-Hydroxy-3-(2-methyl-thiazol-4-yl)-chromen-2-one ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yamanouchi Pharmaceutical Company Ltd. Curated by ChEMBL | Assay Description Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF) | J Med Chem 44: 540-7 (2001) BindingDB Entry DOI: 10.7270/Q2W66MGR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50096000 (3-(2-Fluoro-4-hydroxy-phenyl)-acrylic acid anion) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | PubMed | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yamanouchi Pharmaceutical Company Ltd. Curated by ChEMBL | Assay Description Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF) | J Med Chem 44: 540-7 (2001) BindingDB Entry DOI: 10.7270/Q2W66MGR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50095994 (3-Cyano-7-hydroxycoumarin (2) | 7-Hydroxy-2-oxo-2H...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yamanouchi Pharmaceutical Company Ltd. Curated by ChEMBL | Assay Description Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF) | J Med Chem 44: 540-7 (2001) BindingDB Entry DOI: 10.7270/Q2W66MGR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50096005 (7-Hydroxy-3-(4-methyl-thiazol-2-yl)-chromen-2-one ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yamanouchi Pharmaceutical Company Ltd. Curated by ChEMBL | Assay Description Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF) | J Med Chem 44: 540-7 (2001) BindingDB Entry DOI: 10.7270/Q2W66MGR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50096008 (3-Acetyl-7-hydroxy-chromen-2-one | 3-acetyl-7-hydr...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 4.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yamanouchi Pharmaceutical Company Ltd. Curated by ChEMBL | Assay Description Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF) | J Med Chem 44: 540-7 (2001) BindingDB Entry DOI: 10.7270/Q2W66MGR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50095996 (3-(7-Hydroxy-2-oxo-2H-chromen-3-yl)-3-oxo-propioni...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | PubMed | 5.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yamanouchi Pharmaceutical Company Ltd. Curated by ChEMBL | Assay Description Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF) | J Med Chem 44: 540-7 (2001) BindingDB Entry DOI: 10.7270/Q2W66MGR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50096009 (3-(4-Dimethylamino-benzylidene)-chroman-2,4-dione ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 6.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yamanouchi Pharmaceutical Company Ltd. Curated by ChEMBL | Assay Description Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF) | J Med Chem 44: 540-7 (2001) BindingDB Entry DOI: 10.7270/Q2W66MGR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50095995 (7-HYDROXY-2-OXO-CHROMENE-3-CARBOXYLIC ACID ETHYL E...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank MMDB PDB PubMed | 7.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yamanouchi Pharmaceutical Company Ltd. Curated by ChEMBL | Assay Description Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF) | J Med Chem 44: 540-7 (2001) BindingDB Entry DOI: 10.7270/Q2W66MGR | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50095998 (CHEMBL345292 | Hexylglutathione | L-gamma-glutamyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 3.30E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Yamanouchi Pharmaceutical Company Ltd. Curated by ChEMBL | Assay Description Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF) | J Med Chem 44: 540-7 (2001) BindingDB Entry DOI: 10.7270/Q2W66MGR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50095999 (CHEMBL153339 | Hexane-1-thiol) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 1.74E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
Yamanouchi Pharmaceutical Company Ltd. Curated by ChEMBL | Assay Description Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF) | J Med Chem 44: 540-7 (2001) BindingDB Entry DOI: 10.7270/Q2W66MGR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50095998 (CHEMBL345292 | Hexylglutathione | L-gamma-glutamyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | 2.50E+6 | n/a | n/a | n/a | n/a | n/a |
Yamanouchi Pharmaceutical Company Ltd. Curated by ChEMBL | Assay Description Binding activity towards the active site of macrophage migration inhibitory factor (MIF) | J Med Chem 44: 540-7 (2001) BindingDB Entry DOI: 10.7270/Q2W66MGR | |||||||||||
More data for this Ligand-Target Pair |