Compile Data Set for Download or QSAR

Found 133 hits Enz. Inhib. hit(s) with all data for entry = 50038404   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50375996 (CHEMBL272250) Show SMILES COc1cc2nccc(Oc3ccc4c(cccc4c3)C(=O)NC3CC3)c2cc1C(N)=O Show InChI InChI=1S/C25H21N3O4/c1-31-23-13-21-19(12-20(23)24(26)29)22(9-10-27-21)32-16-7-8-17-14(11-16)3-2-4-18(17)25(30)28-15-5-6-15/h2-4,7-13,15H,5-6H2,1H3,(H2,26,29)(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.370	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of KDR				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50375999 (CHEMBL270342) Show SMILES COc1ccc2c(Oc3ccc4c(cccc4c3)C(=O)NC3CC3)ccnc2c1 Show InChI InChI=1S/C24H20N2O3/c1-28-17-7-10-21-22(14-17)25-12-11-23(21)29-18-8-9-19-15(13-18)3-2-4-20(19)24(27)26-16-5-6-16/h2-4,7-14,16H,5-6H2,1H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.450	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of KDR				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50236362 (CHEMBL429743 | N-(4-chlorophenyl)-6-(6,7-dimethoxy...) Show SMILES COc1cc2nccc(Oc3ccc4c(cccc4c3)C(=O)Nc3ccc(Cl)cc3)c2cc1OC Show InChI InChI=1S/C28H21ClN2O4/c1-33-26-15-23-24(16-27(26)34-2)30-13-12-25(23)35-20-10-11-21-17(14-20)4-3-5-22(21)28(32)31-19-8-6-18(29)7-9-19/h3-16H,1-2H3,(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	0.480	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of KDR				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair				3D Structure (crystal)
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50236856 (CHEMBL272198 | N-cyclopropyl-6-(6,7-dimethoxyquino...) Show SMILES COc1cc2nccc(Oc3ccc4c(cccc4c3)C(=O)NC3CC3)c2cc1OC Show InChI InChI=1S/C25H22N2O4/c1-29-23-13-20-21(14-24(23)30-2)26-11-10-22(20)31-17-8-9-18-15(12-17)4-3-5-19(18)25(28)27-16-6-7-16/h3-5,8-14,16H,6-7H2,1-2H3,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of KDR				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair				3D Structure (crystal)
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50376003 (CHEMBL271984) Show SMILES COc1cc2nccc(Oc3ccc4c(cccc4c3)C(N)=O)c2cc1OC Show InChI InChI=1S/C22H18N2O4/c1-26-20-11-17-18(12-21(20)27-2)24-9-8-19(17)28-14-6-7-15-13(10-14)4-3-5-16(15)22(23)25/h3-12H,1-2H3,(H2,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of KDR				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50375997 (CHEMBL272252) Show SMILES COc1ccc2c(Oc3ccc4c(cccc4c3)C(N)=O)ccnc2c1 Show InChI InChI=1S/C21H16N2O3/c1-25-14-5-8-18-19(12-14)23-10-9-20(18)26-15-6-7-16-13(11-15)3-2-4-17(16)21(22)24/h2-12H,1H3,(H2,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of KDR				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50375993 (CHEMBL259252) Show SMILES COc1cc2nccc(Oc3ccc4c(cccc4c3)C(=O)NC3CCC3)c2cc1OC Show InChI InChI=1S/C26H24N2O4/c1-30-24-14-21-22(15-25(24)31-2)27-12-11-23(21)32-18-9-10-19-16(13-18)5-3-8-20(19)26(29)28-17-6-4-7-17/h3,5,8-15,17H,4,6-7H2,1-2H3,(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of KDR				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50375995 (CHEMBL260532) Show SMILES COc1cc2nccc(Oc3ccc4c(cccc4c3)C(N)=O)c2cc1C(N)=O Show InChI InChI=1S/C22H17N3O4/c1-28-20-11-18-16(10-17(20)22(24)27)19(7-8-25-18)29-13-5-6-14-12(9-13)3-2-4-15(14)21(23)26/h2-11H,1H3,(H2,23,26)(H2,24,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of KDR				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50376009 (CHEMBL409103) Show SMILES CCCNC(=O)c1cccc2cc(Oc3ccnc4cc(OC)c(OC)cc34)ccc12 Show InChI InChI=1S/C25H24N2O4/c1-4-11-27-25(28)19-7-5-6-16-13-17(8-9-18(16)19)31-22-10-12-26-21-15-24(30-3)23(29-2)14-20(21)22/h5-10,12-15H,4,11H2,1-3H3,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of KDR				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50376000 (CHEMBL270556) Show SMILES COc1cc2ncnc(Oc3ccc4c(cccc4c3)C(N)=O)c2cc1OC Show InChI InChI=1S/C21H17N3O4/c1-26-18-9-16-17(10-19(18)27-2)23-11-24-21(16)28-13-6-7-14-12(8-13)4-3-5-15(14)20(22)25/h3-11H,1-2H3,(H2,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of KDR				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50376010 (CHEMBL269871) Show SMILES CCNC(=O)c1cccc2cc(Oc3ccnc4cc(OC)c(OC)cc34)ccc12 Show InChI InChI=1S/C24H22N2O4/c1-4-25-24(27)18-7-5-6-15-12-16(8-9-17(15)18)30-21-10-11-26-20-14-23(29-3)22(28-2)13-19(20)21/h5-14H,4H2,1-3H3,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of KDR				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50376002 (CHEMBL411284) Show SMILES COc1cc2ncnc(Oc3ccc4c(cccc4c3)C(=O)NC3CC3)c2cc1OC Show InChI InChI=1S/C24H21N3O4/c1-29-21-11-19-20(12-22(21)30-2)25-13-26-24(19)31-16-8-9-17-14(10-16)4-3-5-18(17)23(28)27-15-6-7-15/h3-5,8-13,15H,6-7H2,1-2H3,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of KDR				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50376006 (CHEMBL410840) Show SMILES COc1cc2nccc(Oc3ccc4c(cccc4c3)C(=O)NCC(F)(F)F)c2cc1OC Show InChI InChI=1S/C24H19F3N2O4/c1-31-21-11-18-19(12-22(21)32-2)28-9-8-20(18)33-15-6-7-16-14(10-15)4-3-5-17(16)23(30)29-13-24(25,26)27/h3-12H,13H2,1-2H3,(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of KDR				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50376011 (CHEMBL270754) Show SMILES CNC(=O)c1cccc2cc(Oc3ccnc4cc(OC)c(OC)cc34)ccc12 Show InChI InChI=1S/C23H20N2O4/c1-24-23(26)17-6-4-5-14-11-15(7-8-16(14)17)29-20-9-10-25-19-13-22(28-3)21(27-2)12-18(19)20/h4-13H,1-3H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of KDR				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50376004 (CHEMBL271189) Show SMILES COCCCNC(=O)c1cccc2cc(Oc3ccnc4cc(OC)c(OC)cc34)ccc12 Show InChI InChI=1S/C26H26N2O5/c1-30-13-5-11-28-26(29)20-7-4-6-17-14-18(8-9-19(17)20)33-23-10-12-27-22-16-25(32-3)24(31-2)15-21(22)23/h4,6-10,12,14-16H,5,11,13H2,1-3H3,(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of KDR				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50376008 (CHEMBL408211) Show SMILES COc1cc2nccc(Oc3ccc4c(cccc4c3)C(=O)NC(C)C)c2cc1OC Show InChI InChI=1S/C25H24N2O4/c1-15(2)27-25(28)19-7-5-6-16-12-17(8-9-18(16)19)31-22-10-11-26-21-14-24(30-4)23(29-3)13-20(21)22/h5-15H,1-4H3,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of KDR				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50376012 (CHEMBL270755) Show SMILES COc1cc2nccc(Oc3ccc4c(cccc4c3)C(=O)NCC3CC3)c2cc1OC Show InChI InChI=1S/C26H24N2O4/c1-30-24-13-21-22(14-25(24)31-2)27-11-10-23(21)32-18-8-9-19-17(12-18)4-3-5-20(19)26(29)28-15-16-6-7-16/h3-5,8-14,16H,6-7,15H2,1-2H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Aurora B				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50376012 (CHEMBL270755) Show SMILES COc1cc2nccc(Oc3ccc4c(cccc4c3)C(=O)NCC3CC3)c2cc1OC Show InChI InChI=1S/C26H24N2O4/c1-30-24-13-21-22(14-25(24)31-2)27-11-10-23(21)32-18-8-9-19-17(12-18)4-3-5-20(19)26(29)28-15-16-6-7-16/h3-5,8-14,16H,6-7,15H2,1-2H3,(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of KDR				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50376005 (CHEMBL271188) Show SMILES COCCNC(=O)c1cccc2cc(Oc3ccnc4cc(OC)c(OC)cc34)ccc12 Show InChI InChI=1S/C25H24N2O5/c1-29-12-11-27-25(28)19-6-4-5-16-13-17(7-8-18(16)19)32-22-9-10-26-21-15-24(31-3)23(30-2)14-20(21)22/h4-10,13-15H,11-12H2,1-3H3,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of KDR				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50375992 (CHEMBL428961) Show SMILES COc1cc2nccc(Oc3ccc4c(cccc4c3)C(=O)NC3(C)CC3)c2cc1OC Show InChI InChI=1S/C26H24N2O4/c1-26(10-11-26)28-25(29)19-6-4-5-16-13-17(7-8-18(16)19)32-22-9-12-27-21-15-24(31-3)23(30-2)14-20(21)22/h4-9,12-15H,10-11H2,1-3H3,(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of KDR				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50376013 (CHEMBL410903) Show SMILES COc1cc2nccc(Oc3ccc4c(cccc4c3)C(=O)NC3CCCC3)c2cc1OC Show InChI InChI=1S/C27H26N2O4/c1-31-25-15-22-23(16-26(25)32-2)28-13-12-24(22)33-19-10-11-20-17(14-19)6-5-9-21(20)27(30)29-18-7-3-4-8-18/h5-6,9-16,18H,3-4,7-8H2,1-2H3,(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of KDR				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50376006 (CHEMBL410840) Show SMILES COc1cc2nccc(Oc3ccc4c(cccc4c3)C(=O)NCC(F)(F)F)c2cc1OC Show InChI InChI=1S/C24H19F3N2O4/c1-31-21-11-18-19(12-22(21)32-2)28-9-8-20(18)33-15-6-7-16-14(10-15)4-3-5-17(16)23(30)29-13-24(25,26)27/h3-12H,13H2,1-2H3,(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Aurora B				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50236362 (CHEMBL429743 | N-(4-chlorophenyl)-6-(6,7-dimethoxy...) Show SMILES COc1cc2nccc(Oc3ccc4c(cccc4c3)C(=O)Nc3ccc(Cl)cc3)c2cc1OC Show InChI InChI=1S/C28H21ClN2O4/c1-33-26-15-23-24(16-27(26)34-2)30-13-12-25(23)35-20-10-11-21-17(14-20)4-3-5-22(21)28(32)31-19-8-6-18(29)7-9-19/h3-16H,1-2H3,(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Aurora B				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50375994 (CHEMBL260531) Show SMILES COCCNC(=O)c1cccc2cc(Oc3ccnc4cc(OC)c(cc34)C(N)=O)ccc12 Show InChI InChI=1S/C25H23N3O5/c1-31-11-10-28-25(30)18-5-3-4-15-12-16(6-7-17(15)18)33-22-8-9-27-21-14-23(32-2)20(24(26)29)13-19(21)22/h3-9,12-14H,10-11H2,1-2H3,(H2,26,29)(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of KDR				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lyn (Homo sapiens (Human))	BDBM50236856 (CHEMBL272198 | N-cyclopropyl-6-(6,7-dimethoxyquino...) Show SMILES COc1cc2nccc(Oc3ccc4c(cccc4c3)C(=O)NC3CC3)c2cc1OC Show InChI InChI=1S/C25H22N2O4/c1-29-23-13-20-21(14-24(23)30-2)26-11-10-22(20)31-17-8-9-18-15(12-17)4-3-5-19(18)25(28)27-16-6-7-16/h3-5,8-14,16H,6-7H2,1-2H3,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Lyn				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50375998 (CHEMBL272251) Show SMILES COCCNC(=O)c1cccc2cc(Oc3ccnc4cc(OC)ccc34)ccc12 Show InChI InChI=1S/C24H22N2O4/c1-28-13-12-26-24(27)20-5-3-4-16-14-18(7-8-19(16)20)30-23-10-11-25-22-15-17(29-2)6-9-21(22)23/h3-11,14-15H,12-13H2,1-2H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of KDR				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50236362 (CHEMBL429743 | N-(4-chlorophenyl)-6-(6,7-dimethoxy...) Show SMILES COc1cc2nccc(Oc3ccc4c(cccc4c3)C(=O)Nc3ccc(Cl)cc3)c2cc1OC Show InChI InChI=1S/C28H21ClN2O4/c1-33-26-15-23-24(16-27(26)34-2)30-13-12-25(23)35-20-10-11-21-17(14-20)4-3-5-22(21)28(32)31-19-8-6-18(29)7-9-19/h3-16H,1-2H3,(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Lck				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50376010 (CHEMBL269871) Show SMILES CCNC(=O)c1cccc2cc(Oc3ccnc4cc(OC)c(OC)cc34)ccc12 Show InChI InChI=1S/C24H22N2O4/c1-4-25-24(27)18-7-5-6-15-12-16(8-9-17(15)18)30-21-10-11-26-20-14-23(29-3)22(28-2)13-19(20)21/h5-14H,4H2,1-3H3,(H,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Aurora B				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50375992 (CHEMBL428961) Show SMILES COc1cc2nccc(Oc3ccc4c(cccc4c3)C(=O)NC3(C)CC3)c2cc1OC Show InChI InChI=1S/C26H24N2O4/c1-26(10-11-26)28-25(29)19-6-4-5-16-13-17(7-8-18(16)19)32-22-9-12-27-21-15-24(31-3)23(30-2)14-20(21)22/h4-9,12-15H,10-11H2,1-3H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Aurora B				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50376005 (CHEMBL271188) Show SMILES COCCNC(=O)c1cccc2cc(Oc3ccnc4cc(OC)c(OC)cc34)ccc12 Show InChI InChI=1S/C25H24N2O5/c1-29-12-11-27-25(28)19-6-4-5-16-13-17(7-8-18(16)19)32-22-9-10-26-21-15-24(31-3)23(30-2)14-20(21)22/h4-10,13-15H,11-12H2,1-3H3,(H,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human VEGFR1				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lyn (Homo sapiens (Human))	BDBM50376003 (CHEMBL271984) Show SMILES COc1cc2nccc(Oc3ccc4c(cccc4c3)C(N)=O)c2cc1OC Show InChI InChI=1S/C22H18N2O4/c1-26-20-11-17-18(12-21(20)27-2)24-9-8-19(17)28-14-6-7-15-13(10-14)4-3-5-16(15)22(23)25/h3-12H,1-2H3,(H2,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Lyn				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50376003 (CHEMBL271984) Show SMILES COc1cc2nccc(Oc3ccc4c(cccc4c3)C(N)=O)c2cc1OC Show InChI InChI=1S/C22H18N2O4/c1-26-20-11-17-18(12-21(20)27-2)24-9-8-19(17)28-14-6-7-15-13(10-14)4-3-5-16(15)22(23)25/h3-12H,1-2H3,(H2,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Abl				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50376011 (CHEMBL270754) Show SMILES CNC(=O)c1cccc2cc(Oc3ccnc4cc(OC)c(OC)cc34)ccc12 Show InChI InChI=1S/C23H20N2O4/c1-24-23(26)17-6-4-5-14-11-15(7-8-16(14)17)29-20-9-10-25-19-13-22(28-3)21(27-2)12-18(19)20/h4-13H,1-3H3,(H,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Aurora B				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50236856 (CHEMBL272198 | N-cyclopropyl-6-(6,7-dimethoxyquino...) Show SMILES COc1cc2nccc(Oc3ccc4c(cccc4c3)C(=O)NC3CC3)c2cc1OC Show InChI InChI=1S/C25H22N2O4/c1-29-23-13-20-21(14-24(23)30-2)26-11-10-22(20)31-17-8-9-18-15(12-17)4-3-5-19(18)25(28)27-16-6-7-16/h3-5,8-14,16H,6-7H2,1-2H3,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	118	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Aurora B				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50376005 (CHEMBL271188) Show SMILES COCCNC(=O)c1cccc2cc(Oc3ccnc4cc(OC)c(OC)cc34)ccc12 Show InChI InChI=1S/C25H24N2O5/c1-29-12-11-27-25(28)19-6-4-5-16-13-17(7-8-18(16)19)32-22-9-10-26-21-15-24(31-3)23(30-2)14-20(21)22/h4-10,13-15H,11-12H2,1-3H3,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Aurora B				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50375997 (CHEMBL272252) Show SMILES COc1ccc2c(Oc3ccc4c(cccc4c3)C(N)=O)ccnc2c1 Show InChI InChI=1S/C21H16N2O3/c1-25-14-5-8-18-19(12-14)23-10-9-20(18)26-15-6-7-16-13(11-15)3-2-4-17(16)21(22)24/h2-12H,1H3,(H2,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Aurora B				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50375996 (CHEMBL272250) Show SMILES COc1cc2nccc(Oc3ccc4c(cccc4c3)C(=O)NC3CC3)c2cc1C(N)=O Show InChI InChI=1S/C25H21N3O4/c1-31-23-13-21-19(12-20(23)24(26)29)22(9-10-27-21)32-16-7-8-17-14(11-16)3-2-4-18(17)25(30)28-15-5-6-15/h2-4,7-13,15H,5-6H2,1H3,(H2,26,29)(H,28,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	185	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Aurora B				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50376008 (CHEMBL408211) Show SMILES COc1cc2nccc(Oc3ccc4c(cccc4c3)C(=O)NC(C)C)c2cc1OC Show InChI InChI=1S/C25H24N2O4/c1-15(2)27-25(28)19-7-5-6-16-12-17(8-9-18(16)19)31-22-10-11-26-21-14-24(30-4)23(29-3)13-20(21)22/h5-15H,1-4H3,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Aurora B				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50376003 (CHEMBL271984) Show SMILES COc1cc2nccc(Oc3ccc4c(cccc4c3)C(N)=O)c2cc1OC Show InChI InChI=1S/C22H18N2O4/c1-26-20-11-17-18(12-21(20)27-2)24-9-8-19(17)28-14-6-7-15-13(10-14)4-3-5-16(15)22(23)25/h3-12H,1-2H3,(H2,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Aurora B				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50375994 (CHEMBL260531) Show SMILES COCCNC(=O)c1cccc2cc(Oc3ccnc4cc(OC)c(cc34)C(N)=O)ccc12 Show InChI InChI=1S/C25H23N3O5/c1-31-11-10-28-25(30)18-5-3-4-15-12-16(6-7-17(15)18)33-22-8-9-27-21-14-23(32-2)20(24(26)29)13-19(21)22/h3-9,12-14H,10-11H2,1-2H3,(H2,26,29)(H,28,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	233	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Aurora B				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lyn (Homo sapiens (Human))	BDBM50376005 (CHEMBL271188) Show SMILES COCCNC(=O)c1cccc2cc(Oc3ccnc4cc(OC)c(OC)cc34)ccc12 Show InChI InChI=1S/C25H24N2O5/c1-29-12-11-27-25(28)19-6-4-5-16-13-17(7-8-18(16)19)32-22-9-10-26-21-15-24(31-3)23(30-2)14-20(21)22/h4-10,13-15H,11-12H2,1-3H3,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	275	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Lyn				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50376003 (CHEMBL271984) Show SMILES COc1cc2nccc(Oc3ccc4c(cccc4c3)C(N)=O)c2cc1OC Show InChI InChI=1S/C22H18N2O4/c1-26-20-11-17-18(12-21(20)27-2)24-9-8-19(17)28-14-6-7-15-13(10-14)4-3-5-16(15)22(23)25/h3-12H,1-2H3,(H2,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Lck				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50376001 (CHEMBL412278) Show SMILES COCCNC(=O)c1cccc2cc(Oc3ncnc4cc(OC)c(OC)cc34)ccc12 Show InChI InChI=1S/C24H23N3O5/c1-29-10-9-25-23(28)18-6-4-5-15-11-16(7-8-17(15)18)32-24-19-12-21(30-2)22(31-3)13-20(19)26-14-27-24/h4-8,11-14H,9-10H2,1-3H3,(H,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	314	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of KDR				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50236856 (CHEMBL272198 | N-cyclopropyl-6-(6,7-dimethoxyquino...) Show SMILES COc1cc2nccc(Oc3ccc4c(cccc4c3)C(=O)NC3CC3)c2cc1OC Show InChI InChI=1S/C25H22N2O4/c1-29-23-13-20-21(14-24(23)30-2)26-11-10-22(20)31-17-8-9-18-15(12-17)4-3-5-19(18)25(28)27-16-6-7-16/h3-5,8-14,16H,6-7H2,1-2H3,(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Lck				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50376002 (CHEMBL411284) Show SMILES COc1cc2ncnc(Oc3ccc4c(cccc4c3)C(=O)NC3CC3)c2cc1OC Show InChI InChI=1S/C24H21N3O4/c1-29-21-11-19-20(12-22(21)30-2)25-13-26-24(19)31-16-8-9-17-14(10-16)4-3-5-18(17)23(28)27-15-6-7-15/h3-5,8-13,15H,6-7H2,1-2H3,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Aurora B				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50236362 (CHEMBL429743 | N-(4-chlorophenyl)-6-(6,7-dimethoxy...) Show SMILES COc1cc2nccc(Oc3ccc4c(cccc4c3)C(=O)Nc3ccc(Cl)cc3)c2cc1OC Show InChI InChI=1S/C28H21ClN2O4/c1-33-26-15-23-24(16-27(26)34-2)30-13-12-25(23)35-20-10-11-21-17(14-20)4-3-5-22(21)28(32)31-19-8-6-18(29)7-9-19/h3-16H,1-2H3,(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	371	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Aurora A				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50376001 (CHEMBL412278) Show SMILES COCCNC(=O)c1cccc2cc(Oc3ncnc4cc(OC)c(OC)cc34)ccc12 Show InChI InChI=1S/C24H23N3O5/c1-29-10-9-25-23(28)18-6-4-5-15-11-16(7-8-17(15)18)32-24-19-12-21(30-2)22(31-3)13-20(19)26-14-27-24/h4-8,11-14H,9-10H2,1-3H3,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	385	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Aurora B				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50375995 (CHEMBL260532) Show SMILES COc1cc2nccc(Oc3ccc4c(cccc4c3)C(N)=O)c2cc1C(N)=O Show InChI InChI=1S/C22H17N3O4/c1-28-20-11-18-16(10-17(20)22(24)27)19(7-8-25-18)29-13-5-6-14-12(9-13)3-2-4-15(14)21(23)26/h2-11H,1H3,(H2,23,26)(H2,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Aurora B				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Fgr (Homo sapiens (Human))	BDBM50236856 (CHEMBL272198 | N-cyclopropyl-6-(6,7-dimethoxyquino...) Show SMILES COc1cc2nccc(Oc3ccc4c(cccc4c3)C(=O)NC3CC3)c2cc1OC Show InChI InChI=1S/C25H22N2O4/c1-29-23-13-20-21(14-24(23)30-2)26-11-10-22(20)31-17-8-9-18-15(12-17)4-3-5-19(18)25(28)27-16-6-7-16/h3-5,8-14,16H,6-7H2,1-2H3,(H,27,28)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	396	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of FGR				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50375993 (CHEMBL259252) Show SMILES COc1cc2nccc(Oc3ccc4c(cccc4c3)C(=O)NC3CCC3)c2cc1OC Show InChI InChI=1S/C26H24N2O4/c1-30-24-14-21-22(15-25(24)31-2)27-12-11-23(21)32-18-9-10-19-16(13-18)5-3-8-20(19)26(29)28-17-6-4-7-17/h3,5,8-15,17H,4,6-7H2,1-2H3,(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Aurora A				J Med Chem 51: 1668-80 (2008) Article DOI: 10.1021/jm701098w BindingDB Entry DOI: 10.7270/Q2F47Q0C
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 133 total )  |  Next  |  Last  >>

Jump to: