Compile Data Set for Download or QSAR

Found 31 hits Enz. Inhib. hit(s) with all data for entry = 50041613   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50412414 (CHEMBL521203) Show SMILES CCn1ncc2c(NC3CCOCC3)c(cnc12)C(=O)NCc1ccccc1 Show InChI InChI=1S/C21H25N5O2/c1-2-26-20-17(14-24-26)19(25-16-8-10-28-11-9-16)18(13-22-20)21(27)23-12-15-6-4-3-5-7-15/h3-7,13-14,16H,2,8-12H2,1H3,(H,22,25)(H,23,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	3.16	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of human PDE4B in Sf9 cells				Bioorg Med Chem Lett 18: 4237-41 (2008) Article DOI: 10.1016/j.bmcl.2008.05.052 BindingDB Entry DOI: 10.7270/Q2ZP47B3
					More data for this Ligand-Target Pair				3D Structure (crystal)
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50412405 (CHEMBL488634) Show SMILES CCn1ncc2c(NC3CCOCC3)c(cnc12)C(=O)NCC1CCCCC1 Show InChI InChI=1S/C21H31N5O2/c1-2-26-20-17(14-24-26)19(25-16-8-10-28-11-9-16)18(13-22-20)21(27)23-12-15-6-4-3-5-7-15/h13-16H,2-12H2,1H3,(H,22,25)(H,23,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.94	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of human PDE4B in Sf9 cells				Bioorg Med Chem Lett 18: 4237-41 (2008) Article DOI: 10.1016/j.bmcl.2008.05.052 BindingDB Entry DOI: 10.7270/Q2ZP47B3
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50412394 (CHEMBL511488) Show SMILES CCOC(=O)c1cnc2n(CC)ncc2c1NC1CCCCC1 Show InChI InChI=1S/C17H24N4O2/c1-3-21-16-13(11-19-21)15(20-12-8-6-5-7-9-12)14(10-18-16)17(22)23-4-2/h10-12H,3-9H2,1-2H3,(H,18,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of human PDE4B in Sf9 cells				Bioorg Med Chem Lett 18: 4237-41 (2008) Article DOI: 10.1016/j.bmcl.2008.05.052 BindingDB Entry DOI: 10.7270/Q2ZP47B3
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50412411 (CHEMBL538659) Show SMILES CCn1ncc2c(NC3CCOCC3)c(cnc12)C(=O)Nc1ccc(F)cc1 Show InChI InChI=1S/C20H22FN5O2/c1-2-26-19-16(12-23-26)18(24-15-7-9-28-10-8-15)17(11-22-19)20(27)25-14-5-3-13(21)4-6-14/h3-6,11-12,15H,2,7-10H2,1H3,(H,22,24)(H,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12.6	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of human PDE4B in Sf9 cells				Bioorg Med Chem Lett 18: 4237-41 (2008) Article DOI: 10.1016/j.bmcl.2008.05.052 BindingDB Entry DOI: 10.7270/Q2ZP47B3
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50412393 (CHEMBL506982) Show SMILES CCOC(=O)c1cnc2n(CC)ncc2c1NC1CCOCC1 Show InChI InChI=1S/C16H22N4O3/c1-3-20-15-12(10-18-20)14(19-11-5-7-22-8-6-11)13(9-17-15)16(21)23-4-2/h9-11H,3-8H2,1-2H3,(H,17,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15.8	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of human PDE4B in Sf9 cells				Bioorg Med Chem Lett 18: 4237-41 (2008) Article DOI: 10.1016/j.bmcl.2008.05.052 BindingDB Entry DOI: 10.7270/Q2ZP47B3
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50412393 (CHEMBL506982) Show SMILES CCOC(=O)c1cnc2n(CC)ncc2c1NC1CCOCC1 Show InChI InChI=1S/C16H22N4O3/c1-3-20-15-12(10-18-20)14(19-11-5-7-22-8-6-11)13(9-17-15)16(21)23-4-2/h9-11H,3-8H2,1-2H3,(H,17,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15.8	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of human PDE4B in Sf9 cells				Bioorg Med Chem Lett 18: 4237-41 (2008) Article DOI: 10.1016/j.bmcl.2008.05.052 BindingDB Entry DOI: 10.7270/Q2ZP47B3
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50412392 (CHEMBL519588) Show SMILES CCOC(=O)c1cnc2n(CC)ncc2c1NCC(C)C Show InChI InChI=1S/C15H22N4O2/c1-5-19-14-11(9-18-19)13(16-7-10(3)4)12(8-17-14)15(20)21-6-2/h8-10H,5-7H2,1-4H3,(H,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15.8	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of human PDE4B in Sf9 cells				Bioorg Med Chem Lett 18: 4237-41 (2008) Article DOI: 10.1016/j.bmcl.2008.05.052 BindingDB Entry DOI: 10.7270/Q2ZP47B3
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50412412 (CHEMBL488290) Show SMILES CCC(CC)CNC(=O)c1cnc2n(CC)ncc2c1NC1CCOCC1 Show InChI InChI=1S/C20H31N5O2/c1-4-14(5-2)11-22-20(26)17-12-21-19-16(13-23-25(19)6-3)18(17)24-15-7-9-27-10-8-15/h12-15H,4-11H2,1-3H3,(H,21,24)(H,22,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19.9	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of human PDE4B in Sf9 cells				Bioorg Med Chem Lett 18: 4237-41 (2008) Article DOI: 10.1016/j.bmcl.2008.05.052 BindingDB Entry DOI: 10.7270/Q2ZP47B3
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50412410 (CHEMBL486443) Show SMILES CCn1ncc2c(NC3CCOCC3)c(cnc12)C(N)=O Show InChI InChI=1S/C14H19N5O2/c1-2-19-14-11(8-17-19)12(10(7-16-14)13(15)20)18-9-3-5-21-6-4-9/h7-9H,2-6H2,1H3,(H2,15,20)(H,16,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of human PDE4B in Sf9 cells				Bioorg Med Chem Lett 18: 4237-41 (2008) Article DOI: 10.1016/j.bmcl.2008.05.052 BindingDB Entry DOI: 10.7270/Q2ZP47B3
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50412413 (CHEMBL486442) Show SMILES CCn1ncc2c(NC3CCOCC3)c(cnc12)C(=O)N(C)Cc1ccccc1 Show InChI InChI=1S/C22H27N5O2/c1-3-27-21-18(14-24-27)20(25-17-9-11-29-12-10-17)19(13-23-21)22(28)26(2)15-16-7-5-4-6-8-16/h4-8,13-14,17H,3,9-12,15H2,1-2H3,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50.1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of human PDE4B in Sf9 cells				Bioorg Med Chem Lett 18: 4237-41 (2008) Article DOI: 10.1016/j.bmcl.2008.05.052 BindingDB Entry DOI: 10.7270/Q2ZP47B3
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50412408 (CHEMBL488632) Show SMILES CCn1ncc2c(NC3CCOCC3)c(cnc12)C(=O)NC1CCCC1 Show InChI InChI=1S/C19H27N5O2/c1-2-24-18-15(12-21-24)17(22-14-7-9-26-10-8-14)16(11-20-18)19(25)23-13-5-3-4-6-13/h11-14H,2-10H2,1H3,(H,20,22)(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50.1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of human PDE4B in Sf9 cells				Bioorg Med Chem Lett 18: 4237-41 (2008) Article DOI: 10.1016/j.bmcl.2008.05.052 BindingDB Entry DOI: 10.7270/Q2ZP47B3
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50412396 (CHEMBL471738) Show SMILES CCOC(=O)c1cnc2n(CC)ncc2c1NC1CCCC1 Show InChI InChI=1S/C16H22N4O2/c1-3-20-15-12(10-18-20)14(19-11-7-5-6-8-11)13(9-17-15)16(21)22-4-2/h9-11H,3-8H2,1-2H3,(H,17,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63.1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of human PDE4B in Sf9 cells				Bioorg Med Chem Lett 18: 4237-41 (2008) Article DOI: 10.1016/j.bmcl.2008.05.052 BindingDB Entry DOI: 10.7270/Q2ZP47B3
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50412402 (CHEMBL488487) Show SMILES CCCn1ncc2c(NC3CCOCC3)c(cnc12)C(=O)OCC Show InChI InChI=1S/C17H24N4O3/c1-3-7-21-16-13(11-19-21)15(20-12-5-8-23-9-6-12)14(10-18-16)17(22)24-4-2/h10-12H,3-9H2,1-2H3,(H,18,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of human PDE4B in Sf9 cells				Bioorg Med Chem Lett 18: 4237-41 (2008) Article DOI: 10.1016/j.bmcl.2008.05.052 BindingDB Entry DOI: 10.7270/Q2ZP47B3
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50412406 (CHEMBL528772) Show SMILES CCn1ncc2c(NC3CCOCC3)c(cnc12)C(=O)NC1CC1 Show InChI InChI=1S/C17H23N5O2/c1-2-22-16-13(10-19-22)15(20-12-5-7-24-8-6-12)14(9-18-16)17(23)21-11-3-4-11/h9-12H,2-8H2,1H3,(H,18,20)(H,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of human PDE4B in Sf9 cells				Bioorg Med Chem Lett 18: 4237-41 (2008) Article DOI: 10.1016/j.bmcl.2008.05.052 BindingDB Entry DOI: 10.7270/Q2ZP47B3
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50412407 (CHEMBL488633) Show SMILES CCn1ncc2c(NC3CCOCC3)c(cnc12)C(=O)NC1CCN(CC1)C(C)=O Show InChI InChI=1S/C21H30N6O3/c1-3-27-20-17(13-23-27)19(24-16-6-10-30-11-7-16)18(12-22-20)21(29)25-15-4-8-26(9-5-15)14(2)28/h12-13,15-16H,3-11H2,1-2H3,(H,22,24)(H,25,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of human PDE4B in Sf9 cells				Bioorg Med Chem Lett 18: 4237-41 (2008) Article DOI: 10.1016/j.bmcl.2008.05.052 BindingDB Entry DOI: 10.7270/Q2ZP47B3
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50412409 (CHEMBL528771) Show SMILES CCn1ncc2c(NC3CCOCC3)c(cnc12)C(=O)N1CCCC1 Show InChI InChI=1S/C18H25N5O2/c1-2-23-17-14(12-20-23)16(21-13-5-9-25-10-6-13)15(11-19-17)18(24)22-7-3-4-8-22/h11-13H,2-10H2,1H3,(H,19,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of human PDE4B in Sf9 cells				Bioorg Med Chem Lett 18: 4237-41 (2008) Article DOI: 10.1016/j.bmcl.2008.05.052 BindingDB Entry DOI: 10.7270/Q2ZP47B3
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50412398 (CHEMBL488467) Show SMILES CCOC(=O)c1cnc2n(CCO)ncc2c1NC1CCOCC1 Show InChI InChI=1S/C16H22N4O4/c1-2-24-16(22)13-9-17-15-12(10-18-20(15)5-6-21)14(13)19-11-3-7-23-8-4-11/h9-11,21H,2-8H2,1H3,(H,17,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of human PDE4B in Sf9 cells				Bioorg Med Chem Lett 18: 4237-41 (2008) Article DOI: 10.1016/j.bmcl.2008.05.052 BindingDB Entry DOI: 10.7270/Q2ZP47B3
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50412387 (CHEMBL512661) Show SMILES CCOC(=O)c1cnc2n(CC)ncc2c1Nc1ccccc1 Show InChI InChI=1S/C17H18N4O2/c1-3-21-16-13(11-19-21)15(20-12-8-6-5-7-9-12)14(10-18-16)17(22)23-4-2/h5-11H,3-4H2,1-2H3,(H,18,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of human PDE4B in Sf9 cells				Bioorg Med Chem Lett 18: 4237-41 (2008) Article DOI: 10.1016/j.bmcl.2008.05.052 BindingDB Entry DOI: 10.7270/Q2ZP47B3
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50412401 (CHEMBL530550) Show SMILES CCOC(=O)c1cnc2n(ncc2c1NC1CCOCC1)C(C)C Show InChI InChI=1S/C17H24N4O3/c1-4-24-17(22)14-9-18-16-13(10-19-21(16)11(2)3)15(14)20-12-5-7-23-8-6-12/h9-12H,4-8H2,1-3H3,(H,18,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of human PDE4B in Sf9 cells				Bioorg Med Chem Lett 18: 4237-41 (2008) Article DOI: 10.1016/j.bmcl.2008.05.052 BindingDB Entry DOI: 10.7270/Q2ZP47B3
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50098221 (4-Butylamino-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-...) Show SMILES CCCCNc1c(cnc2n(CC)ncc12)C(=O)OCC Show InChI InChI=1S/C15H22N4O2/c1-4-7-8-16-13-11-10-18-19(5-2)14(11)17-9-12(13)15(20)21-6-3/h9-10H,4-8H2,1-3H3,(H,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of human PDE4B in Sf9 cells				Bioorg Med Chem Lett 18: 4237-41 (2008) Article DOI: 10.1016/j.bmcl.2008.05.052 BindingDB Entry DOI: 10.7270/Q2ZP47B3
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50412403 (CHEMBL527645) Show SMILES CCOC(=O)c1cnc2n(C)ncc2c1NC1CCOCC1 Show InChI InChI=1S/C15H20N4O3/c1-3-22-15(20)12-8-16-14-11(9-17-19(14)2)13(12)18-10-4-6-21-7-5-10/h8-10H,3-7H2,1-2H3,(H,16,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of human PDE4B in Sf9 cells				Bioorg Med Chem Lett 18: 4237-41 (2008) Article DOI: 10.1016/j.bmcl.2008.05.052 BindingDB Entry DOI: 10.7270/Q2ZP47B3
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50412389 (CHEMBL507163) Show SMILES CCOC(=O)c1cnc2n(CC)ncc2c1N(C)C1CCOCC1 Show InChI InChI=1S/C17H24N4O3/c1-4-21-16-13(11-19-21)15(14(10-18-16)17(22)24-5-2)20(3)12-6-8-23-9-7-12/h10-12H,4-9H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of human PDE4B in Sf9 cells				Bioorg Med Chem Lett 18: 4237-41 (2008) Article DOI: 10.1016/j.bmcl.2008.05.052 BindingDB Entry DOI: 10.7270/Q2ZP47B3
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50412390 (CHEMBL488292) Show SMILES CCOC(=O)c1cnc2n(CC)ncc2c1NCc1ccc(F)cc1 Show InChI InChI=1S/C18H19FN4O2/c1-3-23-17-14(11-22-23)16(15(10-21-17)18(24)25-4-2)20-9-12-5-7-13(19)8-6-12/h5-8,10-11H,3-4,9H2,1-2H3,(H,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of human PDE4B in Sf9 cells				Bioorg Med Chem Lett 18: 4237-41 (2008) Article DOI: 10.1016/j.bmcl.2008.05.052 BindingDB Entry DOI: 10.7270/Q2ZP47B3
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50412395 (CHEMBL471739) Show SMILES CCOC(=O)c1cnc2n(CC)ncc2c1N1CCCC1 Show InChI InChI=1S/C15H20N4O2/c1-3-19-14-11(10-17-19)13(18-7-5-6-8-18)12(9-16-14)15(20)21-4-2/h9-10H,3-8H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of human PDE4B in Sf9 cells				Bioorg Med Chem Lett 18: 4237-41 (2008) Article DOI: 10.1016/j.bmcl.2008.05.052 BindingDB Entry DOI: 10.7270/Q2ZP47B3
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50412391 (CHEMBL488291) Show SMILES CCOC(=O)c1cnc2n(CC)ncc2c1Nc1ccc(OC)cc1 Show InChI InChI=1S/C18H20N4O3/c1-4-22-17-14(11-20-22)16(15(10-19-17)18(23)25-5-2)21-12-6-8-13(24-3)9-7-12/h6-11H,4-5H2,1-3H3,(H,19,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of human PDE4B in Sf9 cells				Bioorg Med Chem Lett 18: 4237-41 (2008) Article DOI: 10.1016/j.bmcl.2008.05.052 BindingDB Entry DOI: 10.7270/Q2ZP47B3
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50412404 (CHEMBL488485) Show SMILES CCOC(=O)c1cnc2[nH]ncc2c1NC1CCOCC1 Show InChI InChI=1S/C14H18N4O3/c1-2-21-14(19)11-7-15-13-10(8-16-18-13)12(11)17-9-3-5-20-6-4-9/h7-9H,2-6H2,1H3,(H2,15,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of human PDE4B in Sf9 cells				Bioorg Med Chem Lett 18: 4237-41 (2008) Article DOI: 10.1016/j.bmcl.2008.05.052 BindingDB Entry DOI: 10.7270/Q2ZP47B3
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50412388 (CHEMBL519589) Show SMILES CCOC(=O)c1cnc2n(CC)ncc2c1NC(=O)c1ccccc1 Show InChI InChI=1S/C18H18N4O3/c1-3-22-16-13(11-20-22)15(14(10-19-16)18(24)25-4-2)21-17(23)12-8-6-5-7-9-12/h5-11H,3-4H2,1-2H3,(H,19,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of human PDE4B in Sf9 cells				Bioorg Med Chem Lett 18: 4237-41 (2008) Article DOI: 10.1016/j.bmcl.2008.05.052 BindingDB Entry DOI: 10.7270/Q2ZP47B3
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50412397 (CHEMBL530551) Show SMILES CCOC(=O)c1cnc2n(ncc2c1NC1CCOCC1)-c1ccccc1 Show InChI InChI=1S/C20H22N4O3/c1-2-27-20(25)17-12-21-19-16(18(17)23-14-8-10-26-11-9-14)13-22-24(19)15-6-4-3-5-7-15/h3-7,12-14H,2,8-11H2,1H3,(H,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of human PDE4B in Sf9 cells				Bioorg Med Chem Lett 18: 4237-41 (2008) Article DOI: 10.1016/j.bmcl.2008.05.052 BindingDB Entry DOI: 10.7270/Q2ZP47B3
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50412400 (CHEMBL488465) Show SMILES CCOC(=O)c1cnc2n(Cc3ccccc3)ncc2c1NC1CCOCC1 Show InChI InChI=1S/C21H24N4O3/c1-2-28-21(26)18-12-22-20-17(19(18)24-16-8-10-27-11-9-16)13-23-25(20)14-15-6-4-3-5-7-15/h3-7,12-13,16H,2,8-11,14H2,1H3,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of human PDE4B in Sf9 cells				Bioorg Med Chem Lett 18: 4237-41 (2008) Article DOI: 10.1016/j.bmcl.2008.05.052 BindingDB Entry DOI: 10.7270/Q2ZP47B3
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50412399 (CHEMBL488466) Show SMILES CCOC(=O)CCn1ncc2c(NC3CCOCC3)c(cnc12)C(=O)OCC Show InChI InChI=1S/C19H26N4O5/c1-3-27-16(24)5-8-23-18-14(12-21-23)17(22-13-6-9-26-10-7-13)15(11-20-18)19(25)28-4-2/h11-13H,3-10H2,1-2H3,(H,20,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of human PDE4B in Sf9 cells				Bioorg Med Chem Lett 18: 4237-41 (2008) Article DOI: 10.1016/j.bmcl.2008.05.052 BindingDB Entry DOI: 10.7270/Q2ZP47B3
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50412415 (CHEMBL471928) Show SMILES CCOC(=O)c1cnc2n(CC)ncc2c1NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C17H18N4O4S/c1-3-21-16-13(11-19-21)15(14(10-18-16)17(22)25-4-2)20-26(23,24)12-8-6-5-7-9-12/h5-11H,3-4H2,1-2H3,(H,18,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of human PDE4B in Sf9 cells				Bioorg Med Chem Lett 18: 4237-41 (2008) Article DOI: 10.1016/j.bmcl.2008.05.052 BindingDB Entry DOI: 10.7270/Q2ZP47B3
					More data for this Ligand-Target Pair