Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM59112 (Hymenialdisine, 27h) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Genomics Institute of the Novartis Research Foundation | Assay Description In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk. | Chem Biol 11: 247-59 (2004) Article DOI: 10.1016/j.chembiol.2004.01.015 BindingDB Entry DOI: 10.7270/Q2FN14M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM16591 ((4Z)-4-(2-amino-5-oxo-3,5-dihydro-4H-imidazol-4-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 250 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Genomics Institute of the Novartis Research Foundation | Assay Description In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk. | Chem Biol 11: 247-59 (2004) Article DOI: 10.1016/j.chembiol.2004.01.015 BindingDB Entry DOI: 10.7270/Q2FN14M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM50256043 ((Z)-3-bromohymenialdisine | CHEMBL480350 | Hymenia...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 530 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Genomics Institute of the Novartis Research Foundation | Assay Description In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk. | Chem Biol 11: 247-59 (2004) Article DOI: 10.1016/j.chembiol.2004.01.015 BindingDB Entry DOI: 10.7270/Q2FN14M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM7491 ((4Z)-4-(2-amino-5-oxo-3,5-dihydro-4H-imidazol-4-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Genomics Institute of the Novartis Research Foundation | Assay Description In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk. | Chem Biol 11: 247-59 (2004) Article DOI: 10.1016/j.chembiol.2004.01.015 BindingDB Entry DOI: 10.7270/Q2FN14M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM59150 (Hymenialdisine, 28ae) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Genomics Institute of the Novartis Research Foundation | Assay Description In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk. | Chem Biol 11: 247-59 (2004) Article DOI: 10.1016/j.chembiol.2004.01.015 BindingDB Entry DOI: 10.7270/Q2FN14M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM59148 (Hymenialdisine, 28z) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Genomics Institute of the Novartis Research Foundation | Assay Description In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk. | Chem Biol 11: 247-59 (2004) Article DOI: 10.1016/j.chembiol.2004.01.015 BindingDB Entry DOI: 10.7270/Q2FN14M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM59149 (Hymenialdisine, 28v) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Genomics Institute of the Novartis Research Foundation | Assay Description In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk. | Chem Biol 11: 247-59 (2004) Article DOI: 10.1016/j.chembiol.2004.01.015 BindingDB Entry DOI: 10.7270/Q2FN14M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM59142 (Hymenialdisine, 28n) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Genomics Institute of the Novartis Research Foundation | Assay Description In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk. | Chem Biol 11: 247-59 (2004) Article DOI: 10.1016/j.chembiol.2004.01.015 BindingDB Entry DOI: 10.7270/Q2FN14M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM59131 (Hymenialdisine, 28g) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Genomics Institute of the Novartis Research Foundation | Assay Description In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk. | Chem Biol 11: 247-59 (2004) Article DOI: 10.1016/j.chembiol.2004.01.015 BindingDB Entry DOI: 10.7270/Q2FN14M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM59130 (Hymenialdisine, 28t) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Genomics Institute of the Novartis Research Foundation | Assay Description In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk. | Chem Biol 11: 247-59 (2004) Article DOI: 10.1016/j.chembiol.2004.01.015 BindingDB Entry DOI: 10.7270/Q2FN14M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM59102 (Hymenialdisine, 9) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Genomics Institute of the Novartis Research Foundation | Assay Description In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk. | Chem Biol 11: 247-59 (2004) Article DOI: 10.1016/j.chembiol.2004.01.015 BindingDB Entry DOI: 10.7270/Q2FN14M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM59103 (Hymenialdisine, 15) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Genomics Institute of the Novartis Research Foundation | Assay Description In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk. | Chem Biol 11: 247-59 (2004) Article DOI: 10.1016/j.chembiol.2004.01.015 BindingDB Entry DOI: 10.7270/Q2FN14M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM59104 (Hymenialdisine, 18) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Genomics Institute of the Novartis Research Foundation | Assay Description In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk. | Chem Biol 11: 247-59 (2004) Article DOI: 10.1016/j.chembiol.2004.01.015 BindingDB Entry DOI: 10.7270/Q2FN14M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM59105 (Hymenialdisine, 16) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Genomics Institute of the Novartis Research Foundation | Assay Description In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk. | Chem Biol 11: 247-59 (2004) Article DOI: 10.1016/j.chembiol.2004.01.015 BindingDB Entry DOI: 10.7270/Q2FN14M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM59106 (Hymenialdisine, 17) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Genomics Institute of the Novartis Research Foundation | Assay Description In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk. | Chem Biol 11: 247-59 (2004) Article DOI: 10.1016/j.chembiol.2004.01.015 BindingDB Entry DOI: 10.7270/Q2FN14M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM50256044 (5-(2-amino-4-oxo-1H-imidazol-5(4H)-ylidene)-2,3,4,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 800 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Genomics Institute of the Novartis Research Foundation | Assay Description In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk. | Chem Biol 11: 247-59 (2004) Article DOI: 10.1016/j.chembiol.2004.01.015 BindingDB Entry DOI: 10.7270/Q2FN14M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM59107 (Hymenialdisine, 27c) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 550 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Genomics Institute of the Novartis Research Foundation | Assay Description In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk. | Chem Biol 11: 247-59 (2004) Article DOI: 10.1016/j.chembiol.2004.01.015 BindingDB Entry DOI: 10.7270/Q2FN14M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM59108 (Hymenialdisine, 27b) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Genomics Institute of the Novartis Research Foundation | Assay Description In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk. | Chem Biol 11: 247-59 (2004) Article DOI: 10.1016/j.chembiol.2004.01.015 BindingDB Entry DOI: 10.7270/Q2FN14M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM59109 (Hymenialdisine, 27a) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Genomics Institute of the Novartis Research Foundation | Assay Description In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk. | Chem Biol 11: 247-59 (2004) Article DOI: 10.1016/j.chembiol.2004.01.015 BindingDB Entry DOI: 10.7270/Q2FN14M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM59110 (Hymenialdisine, 27e) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 890 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Genomics Institute of the Novartis Research Foundation | Assay Description In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk. | Chem Biol 11: 247-59 (2004) Article DOI: 10.1016/j.chembiol.2004.01.015 BindingDB Entry DOI: 10.7270/Q2FN14M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM59111 (Hymenialdisine, 27f) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Genomics Institute of the Novartis Research Foundation | Assay Description In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk. | Chem Biol 11: 247-59 (2004) Article DOI: 10.1016/j.chembiol.2004.01.015 BindingDB Entry DOI: 10.7270/Q2FN14M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM59113 (Hymenialdisine, 27g) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Genomics Institute of the Novartis Research Foundation | Assay Description In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk. | Chem Biol 11: 247-59 (2004) Article DOI: 10.1016/j.chembiol.2004.01.015 BindingDB Entry DOI: 10.7270/Q2FN14M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM59114 (Hymenialdisine, 27i) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Genomics Institute of the Novartis Research Foundation | Assay Description In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk. | Chem Biol 11: 247-59 (2004) Article DOI: 10.1016/j.chembiol.2004.01.015 BindingDB Entry DOI: 10.7270/Q2FN14M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM59115 (Hymenialdisine, 27j) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Genomics Institute of the Novartis Research Foundation | Assay Description In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk. | Chem Biol 11: 247-59 (2004) Article DOI: 10.1016/j.chembiol.2004.01.015 BindingDB Entry DOI: 10.7270/Q2FN14M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM59116 (Hymenialdisine, 27k) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >10 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Genomics Institute of the Novartis Research Foundation | Assay Description In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk. | Chem Biol 11: 247-59 (2004) Article DOI: 10.1016/j.chembiol.2004.01.015 BindingDB Entry DOI: 10.7270/Q2FN14M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM59117 (CHEMBL151430 | Hymenialdisine, 11b) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Genomics Institute of the Novartis Research Foundation | Assay Description In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk. | Chem Biol 11: 247-59 (2004) Article DOI: 10.1016/j.chembiol.2004.01.015 BindingDB Entry DOI: 10.7270/Q2FN14M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM50358223 (CHEMBL1922122 | US8846696, (3RS,4R)-4-{9-Isopropyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Cyclacel Limited; Cancer Research Technology Limited US Patent | Assay Description The compounds from the examples below were investigated for their CDK2/cyclin E, CDK1/cyclin B, CDK4/cyclin D1 and CDK7/cyclin H, ERK-2, and PKA inhi... | US Patent US8846696 (2014) BindingDB Entry DOI: 10.7270/Q2Z31XCT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM50358211 (CHEMBL1922212 | US8846696, (3S)-3-{9-Isopropyl-6-[...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 4.40E+3 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Cyclacel Limited; Cancer Research Technology Limited US Patent | Assay Description The compounds from the examples below were investigated for their CDK2/cyclin E, CDK1/cyclin B, CDK4/cyclin D1 and CDK7/cyclin H, ERK-2, and PKA inhi... | US Patent US8846696 (2014) BindingDB Entry DOI: 10.7270/Q2Z31XCT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM50358237 (CHEMBL1922211 | US8846696, (3RS,4S)-4-{9-Isopropyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Cyclacel Limited; Cancer Research Technology Limited US Patent | Assay Description The compounds from the examples below were investigated for their CDK2/cyclin E, CDK1/cyclin B, CDK4/cyclin D1 and CDK7/cyclin H, ERK-2, and PKA inhi... | US Patent US8846696 (2014) BindingDB Entry DOI: 10.7270/Q2Z31XCT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM50358210 (CHEMBL1922123 | US8846696, (3R)-3-{9-Isopropyl-6-[...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 6.20E+3 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Cyclacel Limited; Cancer Research Technology Limited US Patent | Assay Description The compounds from the examples below were investigated for their CDK2/cyclin E, CDK1/cyclin B, CDK4/cyclin D1 and CDK7/cyclin H, ERK-2, and PKA inhi... | US Patent US8846696 (2014) BindingDB Entry DOI: 10.7270/Q2Z31XCT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM50358212 (CHEMBL1922218 | US8846696, (2S3R)-3-{9-Isopropyl-6...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 4.90E+3 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Cyclacel Limited; Cancer Research Technology Limited US Patent | Assay Description The compounds from the examples below were investigated for their CDK2/cyclin E, CDK1/cyclin B, CDK4/cyclin D1 and CDK7/cyclin H, ERK-2, and PKA inhi... | US Patent US8846696 (2014) BindingDB Entry DOI: 10.7270/Q2Z31XCT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM50358222 (CHEMBL1922121 | US8846696, (3RS,4R)-4-{9-Isopropyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Cyclacel Limited; Cancer Research Technology Limited US Patent | Assay Description The compounds from the examples below were investigated for their CDK2/cyclin E, CDK1/cyclin B, CDK4/cyclin D1 and CDK7/cyclin H, ERK-2, and PKA inhi... | US Patent US8846696 (2014) BindingDB Entry DOI: 10.7270/Q2Z31XCT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM50358235 (CHEMBL1922209 | US8846696, (3RS,4S)-4-{9-Isopropyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Cyclacel Limited; Cancer Research Technology Limited US Patent | Assay Description The compounds from the examples below were investigated for their CDK2/cyclin E, CDK1/cyclin B, CDK4/cyclin D1 and CDK7/cyclin H, ERK-2, and PKA inhi... | US Patent US8846696 (2014) BindingDB Entry DOI: 10.7270/Q2Z31XCT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM50358221 (CHEMBL1922120 | US8846696, (3RS,4R)-4-{9-Isopropyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Cyclacel Limited; Cancer Research Technology Limited US Patent | Assay Description The compounds from the examples below were investigated for their CDK2/cyclin E, CDK1/cyclin B, CDK4/cyclin D1 and CDK7/cyclin H, ERK-2, and PKA inhi... | US Patent US8846696 (2014) BindingDB Entry DOI: 10.7270/Q2Z31XCT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM50358213 (CHEMBL1922219 | US8846696, (2R3S)-3-{9-Isopropyl-6...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Cyclacel Limited; Cancer Research Technology Limited US Patent | Assay Description The compounds from the examples below were investigated for their CDK2/cyclin E, CDK1/cyclin B, CDK4/cyclin D1 and CDK7/cyclin H, ERK-2, and PKA inhi... | US Patent US8846696 (2014) BindingDB Entry DOI: 10.7270/Q2Z31XCT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM50358236 (CHEMBL1922210 | US8846696, (3RS,4S)-4-{9-Isopropyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Cyclacel Limited; Cancer Research Technology Limited US Patent | Assay Description The compounds from the examples below were investigated for their CDK2/cyclin E, CDK1/cyclin B, CDK4/cyclin D1 and CDK7/cyclin H, ERK-2, and PKA inhi... | US Patent US8846696 (2014) BindingDB Entry DOI: 10.7270/Q2Z31XCT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM84533 (Alsterpaullone derivative, 7 | BDBM50375663) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.230 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Technische Universität Braunschweig | Assay Description Kinase activity assay using GSK-3beta, CDK1/cyclin B and CDK5/p25. | Chembiochem 6: 541-9 (2005) Article DOI: 10.1002/cbic.200400099 BindingDB Entry DOI: 10.7270/Q2FX780X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM84532 (Alsterpaullone derivative, 6) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Technische Universität Braunschweig | Assay Description Kinase activity assay using GSK-3beta, CDK1/cyclin B and CDK5/p25. | Chembiochem 6: 541-9 (2005) Article DOI: 10.1002/cbic.200400099 BindingDB Entry DOI: 10.7270/Q2FX780X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM84531 (Alsterpaullone derivative, 5) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Technische Universität Braunschweig | Assay Description Kinase activity assay using GSK-3beta, CDK1/cyclin B and CDK5/p25. | Chembiochem 6: 541-9 (2005) Article DOI: 10.1002/cbic.200400099 BindingDB Entry DOI: 10.7270/Q2FX780X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM164884 (US9067888, 34) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.88E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
AstraZeneca AB US Patent | Assay Description In vitro kinase assay analysis may be performed using standard techniques described in the art. These techniques are also used by commercial services... | US Patent US9067888 (2015) BindingDB Entry DOI: 10.7270/Q2CR5S4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM84529 (Alsterpaullone derivative, 3) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 80 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Technische Universität Braunschweig | Assay Description Kinase activity assay using GSK-3beta, CDK1/cyclin B and CDK5/p25. | Chembiochem 6: 541-9 (2005) Article DOI: 10.1002/cbic.200400099 BindingDB Entry DOI: 10.7270/Q2FX780X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM7262 (14-nitro-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | 35 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Technische Universität Braunschweig | Assay Description Kinase activity assay using GSK-3beta, CDK1/cyclin B and CDK5/p25. | Chembiochem 6: 541-9 (2005) Article DOI: 10.1002/cbic.200400099 BindingDB Entry DOI: 10.7270/Q2FX780X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM84530 (Alsterpaullone derivative, 4) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Technische Universität Braunschweig | Assay Description Kinase activity assay using GSK-3beta, CDK1/cyclin B and CDK5/p25. | Chembiochem 6: 541-9 (2005) Article DOI: 10.1002/cbic.200400099 BindingDB Entry DOI: 10.7270/Q2FX780X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM164883 (US9067888, 33) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 94 | n/a | n/a | n/a | n/a | 7.5 | n/a |
AstraZeneca AB US Patent | Assay Description In vitro kinase assay analysis may be performed using standard techniques described in the art. These techniques are also used by commercial services... | US Patent US9067888 (2015) BindingDB Entry DOI: 10.7270/Q2CR5S4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM129352 (US8802686, 10) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 82 | n/a | n/a | n/a | n/a | 8.0 | 22 |
Bayer Intellectual Property GmbH US Patent | Assay Description CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the... | US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM129350 (US8802686, 8) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 43 | n/a | n/a | n/a | n/a | 8.0 | 22 |
Bayer Intellectual Property GmbH US Patent | Assay Description CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the... | US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM129354 (US8802686, 12) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 51 | n/a | n/a | n/a | n/a | 8.0 | 22 |
Bayer Intellectual Property GmbH US Patent | Assay Description CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the... | US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM129355 (US8802686, 13) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 130 | n/a | n/a | n/a | n/a | 8.0 | 22 |
Bayer Intellectual Property GmbH US Patent | Assay Description CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the... | US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM129356 (US8802686, 14) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 740 | n/a | n/a | n/a | n/a | 8.0 | 22 |
Bayer Intellectual Property GmbH US Patent | Assay Description CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the... | US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM129357 (US8802686, 15) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 280 | n/a | n/a | n/a | n/a | 8.0 | 22 |
Bayer Intellectual Property GmbH US Patent | Assay Description CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the... | US Patent US8802686 (2014) BindingDB Entry DOI: 10.7270/Q26W98R1 | |||||||||||
More data for this Ligand-Target Pair |
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